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1.
Rev Assoc Med Bras (1992) ; 66(8): 1036-1042, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32935795

RESUMO

OBJECTIVE: The association between gynecological diagnoses and their distribution across healthcare sectors benefits health promotion and the identification of topics for continued education of gynecological care. This study aimed to identify healthcare diagnoses and referral flow in climacteric women. METHODS: This is a cross-sectional study conducted at the Women's Health Clinic of the University Hospital, University of São Paulo, with a reference to gynecology and training for Residents of Family and Community Medicine, between 2017 and 2018. The medical records of 242 women whose sociodemographic and clinical information, gynecological diagnoses, and distribution of healthcare services (primary, secondary, and tertiary) had been processed were collected. Statistical analysis included the chi-square test and odds ratio. RESULTS: Smoking (OR = 2.27, 95% CI 1.05-4.89; p = 0.035) was associated with the referral of climacteric women to higher complexity services. Considering the distribution of non-oncological diagnoses in climacteric patients, the chance of women being referred to medium- and high-complexity health services presented a 2-fold increase in cases of breast diseases, a 2.35-fold increase in cases of noninflammatory disorders of the female genital tract, and a 3-fold increase in cases of inflammatory diseases of the pelvic organs. CONCLUSION: Climacteric women aged over 55 years, postmenopausal women, and smoking women were most frequently referred to medium- and high-complexity outpatient surgery.


Assuntos
Climatério , Estudos Transversais , Feminino , Humanos , Encaminhamento e Consulta , Saúde da Mulher
2.
Enferm. foco (Brasília) ; 11(1): 44-49, jun. 2020.
Artigo em Português | LILACS, BDENF - Enfermagem | ID: biblio-1102523

RESUMO

Objetivo: conhecer o que as mulheres e os homens com vínculo trabalhista ou estudantil da Universidade Federal de São João del-Rei, Campus Centro-Oeste, sabem sobre o climatério e menopausa. Metodologia: estudo de caso único, com abordagem qualitativa e fundamentada na técnica de Análise Crítica do Discurso. A pesquisa contou com 43 participantes, sendo 15 mulheres e 28 homens. Resultados: a distinção entre climatério e menopausa nem sempre é clara para os participantes, sendo desconhecidas, especialmente, pelos participantes do sexo masculino. Além disso, o climatério é um período em que as mulheres queixam-se de vários sintomas, tanto biológicos quanto psicológicos. Considerações finais: há uma defasagem no conhecimento das mulheres referente ao climatério e à menopausa. Nota-se o desconhecimento total dos homens referente ao climatério e poucos sabem o que é a menopausa. Em face ao exposto evidencia-se a necessidade de mais estudos que busquem explorar a temática menopausa/ climatério. (AU)


Objective: to know the that women and men with a labor or student bond of the Federal University of São João del-Rei, Campus Central-West, know about the climacteric and menopause. Method: a unique case study, with a qualitative approach and based on the technique of Critical Discourse Analysis. The survey counted on 43 participants, being 15 women and 28 men. Results: the distinction between the phases of female life understood by the climacteric and the menopause is not always clear to the participants, being unknown, especially, by the male participants. In addition, it is a time when women complain of various symptoms, both biological and psychological. Conclusion: there is a lag in women's knowledge regarding such periods. Men's total ignorance of the climacteric is noted, and few know what menopause is. In view of the above, it is evident the need for further studies that seek to explore the menopausal / climacteric theme. (AU)


Objetivo: conocer el desarrollo que las mujeres y los hombres con vínculo laboral o estudiantil de la Universidad Federal de San Juan del Rey, Campus Centro-Oeste, saben sobre el climaterio y la menopausia. Metodo: estudio de caso único, con abordaje cualitativo y fundamentado en la técnica de Análisis Crítico del Discurso. La encuesta contó con 43 participantes, siendo 15 mujeres y 28 hombres. Resultados: la distinción entre las fases de la vida femenina comprendidas por el climaterio y la menopausia no siempre es clara para los participantes, siendo desconocidas, especialmente, por los participantes del sexo masculino. Además, es un período en que las mujeres se quejan de varios síntomas, tanto biológicos y psicológicos. Conclusión: hay un desfase en el conocimiento de las mujeres referente a tales períodos. Se nota el desconocimiento total de los hombres referente al climaterio y pocos saben lo que es la menopausia. En vista de lo expuesto se evidencia la necesidad de más estudios que busquen explorar la temática menopausia / climaterio. (AU)


Assuntos
Mulheres , Humanos , Climatério , Menopausa , Conhecimento
3.
ABCS health sci ; 45: [1-6], 02 jun 2020. ilus, tab
Artigo em Inglês | LILACS | ID: biblio-1097551

RESUMO

INTRODUCTION: Climacteric is a period of transition between the reproductive and nonreproductive phases of the woman, due to hypoestrogenism. Some symptoms such as vasomotor and urogenital disorders and sexual dysfunctions are characteristics of this period that can interfere negatively in women´s quality of life. However, specific exercises can positively influence the improvement of these conditions. OBJECTIVE: To verify the impact of a physiotherapist supervised exercise protocol on menopausal symptoms, sexuality and quality of life of climacteric women. METHODS: A descriptive study with physiotherapeutic intervention through a specific exercise protocol. Participated in the study 18 women attended to Instituto da Mulher e Gestante, in the city of Santos (SP). RESULTS: The women underwent initial physiotherapeutic evaluation, answered the Sexuality Questionnaire Female Sexual Function Index, Kupperman Menopausal Index and SF-36 quality of life. They were then submitted to health education about climacteric period and also to a physiotherapist supervised exercise group, once a week, lasting 50 minutes, for 12 weeks. The same questionnaires were reapplied at the end of this period. CONCLUSION: The protocol of specific group exercises supervised by physiotherapist did not influence sexual function, but it was effective for better quality of life and decreased significantly climacteric symptomatology.


INTRODUÇÃO: O climatério é um período de transição entre as fases reprodutiva e não reprodutiva da mulher consequente ao hipoestrogenismo. Sintomas vasomotores, alterações do trato urogenital e disfunções sexuais são algumas condições características deste período que podem interferir negativamente na qualidade de vida. Entretanto, exercícios específicos podem influenciar positivamente na melhora dessas condições. OBJETIVO: Verificar o impacto de um protocolo de exercícios supervisionado por fisioterapeuta nos sintomas menopausais, na sexualidade e na qualidade de vida de mulheres no climatério. MÉTODOS: Estudo quase-experimental com intervenção fisioterapêutica por meio de protocolo de exercícios específicos. Participaram do estudo 18 mulheres usuárias do Instituto da Mulher e da Gestante, do município de Santos (SP). RESULTADOS: As mulheres foram submetidas à avaliação fisioterapêutica inicial, responderam aos questionários de sexualidade Female Sexual Function Index, Índice Menopausal de Kupperman e de qualidade de vida SF-36. Foram então submetidas a grupo de exercício supervisionado por fisioterapeuta, uma vez por semana, com duração de 50 minutos, por 12 semanas. Os mesmos questionários foram reaplicados ao final deste período. CONCLUSÃO: O protocolo de exercícios específicos em grupo e supervisionado por fisioterapeuta não influenciou a função sexual, mas foi eficaz para melhor qualidade de vida e enfrentamento da sintomatologia do climatério.


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Qualidade de Vida , Climatério , Sexualidade , Terapia por Exercício
4.
Arch Endocrinol Metab ; 64(3): 276-281, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32555994

RESUMO

OBJECTIVE: Climacterium is associated with elevated leptin levels and increased risk of cardiovascular disorders. Conflicting data diverge on whether high leptin levels in climacterium reflect increasing adipose mass or, at least partially, age-related hormonal changes. This study addresses this issue in women from a Brazilian state with a low human development index. SUBJECTS AND METHODS: A case-control study was conducted, enrolling 136 women from the state of Maranhão, 52 (38.2%) climacteric and 84 (61.8%) non-climacteric. Biometric, biochemical, hormonal and immunological parameters were analyzed. RESULTS: Climacteric women showed a moderately increased waist/hip ratio (0.894 versus 0.834, p < 0.05), sustained body mass index (27.46 versus 28.68, p > 0.05) increased leptin levels (9.59 versus 7.13, p < 0.05) and no evidence of metabolic syndrome. No other parameters were altered. The climacteric cohort didn't show significant body fat gains but displayed a typical age-related redistribution of adipose tissue. Even so, leptin levels were significantly elevated compared with non-climacteric women. CONCLUSIONS: Altogether, these data support the hypothesis that leptin is elevated, at least partially, as a function of age and climacterium and is not necessarily correlated with metabolic dysfunction and systemic inflammation. Further studies are needed to evaluate the impact of higher leptin levels on postmenopausal women. Arch Endocrinol Metab. 2020;64(3):276-81.


Assuntos
Adiposidade/fisiologia , Climatério/sangue , Leptina/sangue , Adulto , Fatores Etários , Idoso , Biomarcadores/sangue , Estudos de Casos e Controles , Climatério/fisiologia , Estudos de Coortes , Feminino , Humanos , Pessoa de Meia-Idade , Fatores Socioeconômicos
5.
Maturitas ; 136: 1-6, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32386660

RESUMO

OBJECTIVES: To investigate the influence and specificity of sociodemographic and psychological factors on the perception of symptoms associated with menopause. STUDY DESIGN: Data are based on a nationwide cross-sectional survey study in Germany. A representative sample of 1350 females aged 14-95 years was examined. Sociodemographic factors, perceived stress, and self-efficacy were assessed. Women were divided into three age groups (young women ≤ 44 years; perimenopausal women 45-60 years; older women ≥ 61 years), and the Menopause Rating Scale (MRS) was used over the entire life span. MAIN OUTCOME MEASURES: Total score on the Menopause Rating Scale (MRS) and hot flushes/sweating assessed via the MRS. RESULTS: The MRS total score increased with age. Both MRS total score and hot flushes were positively associated with perceived stress in all three age groups. The MRS total score was negatively associated with self-efficacy; for hot flushes, this association could be shown for perimenopausal women only. Furthermore, interaction effects between perceived stress and self-efficacy were found: in perimenopausal and older women, the association between perceived stress and the MRS total score was stronger the lower self-efficacy was. This interaction effect was not observed in younger women. No interaction effect was found in any age group for hot flushes. CONCLUSIONS: Our data indicate that self-efficacy influences the severity of symptoms measured with the MRS. Interventions aimed to reduce stress and strengthen self-efficacy could lead to a lower symptom burden in perimenopausal women.


Assuntos
Climatério/fisiologia , Climatério/psicologia , Autoeficácia , Estresse Psicológico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Alemanha , Fogachos , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários , Sudorese , Adulto Jovem
6.
Rev. enferm. UFPE on line ; 14: [1-9], 2020. ilus, tab, graf
Artigo em Português | BDENF - Enfermagem | ID: biblio-1100693

RESUMO

Objetivo: avaliar os marcadores subclínicos de doenças cardiovasculares e os hábitos alimentares em mulheres no período do climatério. Método: trata-se de um estudo quantitativo, descritivo, transversal que avaliou o estado nutricional, exames bioquímicos, espessura da camada íntima média da artéria carótida e os hábitos alimentares de 20 mulheres. Incluíram-se no estudo aquelas que apresentaram espessamento da camada arterial. Analisaram-se os dados no software SPSS versão 18.0. Resultados: observaram-se estado de sobrepeso e risco muito elevado para o desenvolvimento de doenças cardiovasculares pelo perímetro da cintura. Verificaram-se alterações no colesterol LDL e colesterol total. Conclusão: trata-se de uma população com múltiplos riscos cardiovasculares. Sugere-se que a avaliação integral do estado de saúde de mulheres nesse período seja realizada. Descritores: Climatério; Estado Nutricional; Comportamento Alimentar; Doenças das Artérias Carótida; Riscos Cardiovasculares.(AU)


Objective: to evaluate the subclinical markers of cardiovascular disease and eating habits in women during the climacteric period. Method: this is a quantitative, descriptive, cross-sectional study that assessed nutritional status, biochemical tests, thickness of the middle intima layer of the carotid artery and the eating habits of 20 women. The study included those with thickening of the arterial layer. The data were analyzed using SPSS software version 18.0. Results: there was a state of overweight and an extremely high risk for the development of cardiovascular diseases around the waist. There were changes in LDL cholesterol and total cholesterol. Conclusion: this is a population with multiple cardiovascular risks. It is suggested that the full assessment of the health status of women in this period be carried out.(AU)


Objetivo: evaluar los marcadores subclínicos de enfermedades cardiovasculares y hábitos alimentarios en mujeres durante el período climatérico. Método: se trata de un estudio cuantitativo, descriptivo, transversal que evaluó el estado nutricional, las pruebas bioquímicas, el grosor de la capa íntima media de la arteria carótida y los hábitos alimentarios de 20 mujeres. El estudio incluyó a aquellos con engrosamiento de la capa arterial. Los datos se analizaron con el software SPSS versión 18.0. Resultados: hubo un estado de sobrepeso y un riesgo muy alto de desarrollar enfermedades cardiovasculares alrededor de la cintura. Hubo cambios en el colesterol LDL y el colesterol total. Conclusión: esta es una población con múltiples riesgos cardiovasculares. Se sugiere realizar una evaluación completa del estado de salud de las mujeres en este período.(AU)


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Idoso , Mulheres , Perfil de Saúde , Climatério , Biomarcadores , Doenças Cardiovasculares , Doenças das Artérias Carótidas , Estado Nutricional , Fatores de Risco , Saúde da Mulher , Dieta , Epidemiologia Descritiva , Estudos Transversais , Assistência Integral à Saúde
7.
Nursing (Säo Paulo) ; 23(264): 3996-4001, maio.2020.
Artigo em Português | LILACS, BDENF - Enfermagem | ID: biblio-1102701

RESUMO

Este estudo objetivou descrever a influência dos sintomas climatéricos na qualidade de vida de mulheres nessa fase do ciclo reprodutivo. Trata-se de uma pesquisa descritiva, quantitativa, transversal e epidemiológica que iniciou após parecer favorável do Comitê de ética pela numeração 1.655.600. Participaram da pesquisa mulheres com idade entre 40 e 64 anos de idade usuárias de uma ESF da cidade de Montes Claros-MG que consentiram participar da pesquisa através do Termo de Consentimentos Livre e Esclarecido. O instrumento de coleta utilizado foi o questionário sociodemográfico, QSM e o Índice de Kupperman e Blatt com análise descritiva e comparativa dos dados. Nos resultados pode-se observar que a maioria das mulheres apresentou sintomas entre moderados e acentuados, totalizando 60,9% de acordo o Índice de Kupperman e Blatt, e que a maioria das participantes, 52,9%, apresentaram médias de resposta no QSM acima da média geral da população estudada, o que aponta que os sintomas vivenciados nesta fase da vida levam à alterações na sua qualidade de vida.(AU)


Assuntos
Humanos , Feminino , Climatério , Menopausa , Saúde da Mulher , Qualidade de Vida , Serviços de Saúde da Mulher
8.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 12: 311-318, jan.-dez. 2020. tab
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem | ID: biblio-1051220

RESUMO

Objetivo: Analisar a sintomatologia climatérica em mulheres com doença arterial coronariana. Métodos: Participaram quarenta (40) mulheres, clientes do Ambulatório de Cardiologia do Hospital da Universidade Federal do Maranhão. Utilizou-se a Escala de Avaliação da Menopausa. Pesquisa aprovada pelo Comitê de Ética em Pesquisa da Escola de Enfermagem de Ribeirão Preto, Universidade São Paulo sob o número 293.900. Resultados: Os sintomas mais frequentes relatados foram ansiedade, mal estar no coração, irritabilidade, problemas musculares e nas articulações. Os sintomas mais intensos foram os problemas musculares e nas articulações, ansiedade, mal estar no coração, esgotamento físico e mental. A média de escore dos sintomas psicológicos foi 23,8; nos sintomas somáticos foi 23,6 e nos sintomas urogenitais foi 9,2. Conclusão: Os sintomas climatéricos parecem ser confundidos com problemas inerentes à idade e percebidos com mais intensidade na presença de doenças, inclusive a doença arterial coronariana


Objective: to Analyze the climate symptoms in women with coronary artery disease. Methods: participated in 40 (40) women, Cardiology outpatient clinic of the Hospital of the Federal University of Maranhão. It was menopause assessment scale. Research approved by the Research Ethics Committee of the school of nursing of Ribeirão Preto, University of São Paulo under number 293.900. Results: The most frequent symptoms reported were anxiety, malaise in the heart, irritability, muscle and joint problems. The most intense symptoms were the muscle problems and joint pain, anxiety, malaise in the heart, physical and mental exhaustion. The average score of the psychological symptoms was 23.8; somatic symptoms was 23.6 and urogenital symptoms was 9.2. Conclusion: climate symptoms seem to be confused with inherent problems of age and perceived with more intensity in the presence of diseases, including coronary artery disease


Objetivo: analizar los síntomas de clima en mujeres con enfermedad arterial coronaria. Métodos: participaron en 40 (40) mujeres, clínica de consulta externa de Cardiología del Hospital de la Universidad Federal de Maranhão. Fue la escala de evaluación de la menopausia. Investigación aprobado por el Comité de ética de investigación de la escuela de enfermería de Ribeirão Preto, Universidad de São Paulo bajo número 293.900. Resultados: informaron de los síntomas más frecuentes fueron ansiedad, malestar en el corazón, irritabilidad, problemas musculares y la articulaciones. Los síntomas más intensos fueron los problemas musculares y dolor en las articulaciones, ansiedad, malestar en el corazón, agotamiento físico y mental. La puntuación media de los síntomas psicológicos fue 23,8; síntomas somáticos fue 23.6 y síntomas urogenitales 9.2. Conclusion: clima síntomas parecen ser confundidos con problemas inherentes de la edad y percibe con más intensidad en la presencia de enfermedades, incluyendo enfermedad arterial coronaria


Assuntos
Humanos , Feminino , Adulto , Pessoa de Meia-Idade , Doença da Artéria Coronariana , Climatério , Doença das Coronárias , Terapia de Reposição de Estrogênios , Fatores de Risco , Saúde da Mulher , Interacionismo Simbólico
9.
Adv Gerontol ; 32(4): 516-523, 2019.
Artigo em Russo | MEDLINE | ID: mdl-31800178

RESUMO

The aim of our study is to search diagnostic tools for early detection of prenosological melatonin deficiency in postmenopausal women and women in menopausal transition with climacteric syndrome for establishment effective personalized prevention and treatment programs. In this study 221 women were enrolled. They were divided into four groups: the 1st group - 39 women in menopausal transition with climacteric syndrome, the 2nd group - 104 menopausal women with climacteric syndrome, the 3rd group - 41 women with physiological menopause, the 4th group - 37 healthy women in reproductive-age. The study was conducted using the test for detecting melatonin deficiency, women's health questionnaire (WHQ), and morning level detection of 6-sulfatoxymelatonin in urine. A new prenosological state - perimenopausal melatonin deficiency syndrome was build on the data obtained. It is appropriate to evaluate prognosis of melatonin treatment in women with climacteric syndrome during the planning of personalized prevention and treatment programs. The assessment of prognosis is carried out with the help of the discriminant mathematical model, which is the basis of personalized management of quality of life in women with climacteric syndrome. This system is based on participatory principles.


Assuntos
Climatério , Melatonina , Medicina de Precisão , Qualidade de Vida , Adulto , Feminino , Humanos , Melatonina/deficiência , Melatonina/urina , Menopausa , Pessoa de Meia-Idade , Perimenopausa/urina , Inquéritos e Questionários , Síndrome
10.
PLoS One ; 14(12): e0225886, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31800597

RESUMO

European pears (Pyrus communis L.) require a range of cold-temperature exposure to induce ethylene biosynthesis and fruit ripening. Physiological and hormonal responses to cold temperature storage in pear have been well characterized, but the molecular underpinnings of these phenomena remain unclear. An established low-temperature conditioning model was used to induce ripening of 'D'Anjou' and 'Bartlett' pear cultivars and quantify the expression of key genes representing ripening-related metabolic pathways in comparison to non-conditioned fruit. Physiological indicators of pear ripening were recorded, and fruit peel tissue sampled in parallel, during the cold-conditioning and ripening time-course experiment to correlate gene expression to ontogeny. Two complementary approaches, Nonparametric Multi-Dimensional Scaling and efficiency-corrected 2-(ΔΔCt), were used to identify genes exhibiting the most variability in expression. Interestingly, the enhanced alternative oxidase (AOX) transcript abundance at the pre-climacteric stage in 'Bartlett' and 'D'Anjou' at the peak of the conditioning treatments suggests that AOX may play a key and a novel role in the achievement of ripening competency. There were indications that cold-sensing and signaling elements from ABA and auxin pathways modulate the S1-S2 ethylene transition in European pears, and that the S1-S2 ethylene biosynthesis transition is more pronounced in 'Bartlett' as compared to 'D'Anjou' pear. This information has implications in preventing post-harvest losses of this important crop.


Assuntos
Climatério/genética , Temperatura Baixa , Frutas/fisiologia , Proteínas Mitocondriais/genética , Oxirredutases/genética , Proteínas de Plantas/genética , Pyrus/fisiologia , Transcrição Genética
11.
PLoS One ; 14(12): e0218497, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31830047

RESUMO

This study aims to investigate the association between health conditions and overweight in climacteric women assisted by primary care professionals. It is a cross-sectional study conducted with 874 women from 40 to 65 years of age, selected by probabilistic sampling between August 2014 and August 2015. In addition to the outcome variable, overweight and obesity, other variables such as sociodemographic, reproductive, clinical, eating and behavioural factors were evaluated. Descriptive analyses of the variables investigated were performed to determine their frequency distributions. Then, bivariate analyses were performed through Poisson regression. For the multivariate analyses, hierarchical Poisson regression was used to identify factors associated with overweight and obesity in the climacteric period. The prevalence of overweight and obesity was 74%. Attending public school (PR: 1.30-95% CI 1.14-1.50), less schooling (PR: 1.11-95% CI 1.01-1.23), gout (PR: 1.18-95% CI 1.16-1.44), kidney disease (PR: 1.18-95% CI 1.05-1.32), metabolic syndrome (MS) (PR: 1.19-95% CI 1.05-1.34) and fat intake (PR: 1.12-95% CI 1.02-1.23) were considered risk factors for overweight. Having the first birth after 18 years of age (PR: 0.89-95% CI 0.82 to 0.97) was shown to be a protective factor for overweight and obesity. The presence of overweight and obesity is associated with sociodemographic, reproductive, clinical and eating habits.


Assuntos
Climatério , Obesidade/epidemiologia , Sobrepeso/epidemiologia , Adulto , Idoso , Índice de Massa Corporal , Brasil/epidemiologia , Estudos Transversais , Feminino , Humanos , Pessoa de Meia-Idade , Prevalência , Fatores de Risco
12.
Rev. Rol enferm ; 42(11/12): 728-733, nov.-dic. 2019. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-190489

RESUMO

La menopausia supone una etapa de grandes cambios para la mujer. De entre las principales complicaciones que podemos encontrar, una de ellas corresponde al Síndrome Genitourinario de la Menopausia (SGM) de alta prevalencia en la salud de la mujer climatérica y que se manifiesta mediante la atrofia vulvovaginal, sequedad, dispareunia e irritación, principalmente. Pese a su gran prevalencia, es poco consultado en las valoraciones de salud por parte de los profesionales sanitarios, y se desconocen las terapias alternativas al tratamiento estrogénico tópico como la aplicación de fórmulas con Ácido Hialurónico (AH), un polisacárido natural de la matriz extracelular de la piel que ha mostrado una mejora significativa en el alivio de los síntomas, por su alta capacidad en la retención de agua y en la regeneración de los tejidos. Este estudio supone una actualización de las terapias disponibles con AH y sus principales resultados en el control de las manifestaciones del síndrome


Menopause is a stage of great change for women. Among the main complications that we can find, one of them corresponds to the Genitourinary Syndrome of Menopause (GSM) of high prevalence in the health of the woman climacteric and that is manifested by the vulvovaginal atrophy, dryness, dyspareunia and irritation, mainly. Despite its great prevalence, it is rarely consulted in health assessments by healthcare professionals, and alternative therapies to topical estrogenic treatment such as the application of formulas with Hyaluronic Acid (HA), a natural polysaccharide of the extracellular matrix of the skin that has shown a significant improvement in symptom relief, due to its high capacity in water retention and tissue regeneration, are unknown. This study implies an update of the therapies available with HA and its main results in the control of the manifestations of the syndrome


Assuntos
Humanos , Feminino , Ácido Hialurônico/uso terapêutico , Doenças Urogenitais Femininas/tratamento farmacológico , Adjuvantes Imunológicos/uso terapêutico , Dispareunia/tratamento farmacológico , Climatério/efeitos dos fármacos , Pós-Menopausa , Síndrome , Cuidados de Enfermagem
13.
ABCS health sci ; 44(3): 203-208, 20 dez 2019. tab
Artigo em Inglês, Português | LILACS | ID: biblio-1047754

RESUMO

Durante o climatério, período em que as gônadas femininas cessam sua função, a deficiência de estrógenos, especialmente do estradiol, provoca alterações importantes na cavidade bucal, interferindo em mecanismos inflamatórios, secreção salivar, metabolismo do colágeno, entre outros. Por meio de uma revisão de literatura, esse estudo teve como objetivo, ver a influência das alterações hormonais advindas do período de climatério nos tecidos bucais, proporcionando ao cirurgião dentista informações em relação às consequências e cuidados relacionados a esta fase da vida da mulher. Nesse período, as mulheres tornam-se mais suscetíveis a alterações tais como: osteopenia e osteoporose dos maxilares, hipossalivação, doenças periodontais, entre outros. O tratamento preventivo por meio de remoção de placa, adequação do meio bucal e orientação antes e durante o climatério são os melhores meios de minimizar os problemas bucais advindos dessa fase da vida da mulher.


During the climacteric period, when female gonads cease their function, estrogen deficiency, especially estradiol, causes important changes in the oral cavity, interfering in inflammatory mechanisms, salivary secretion, collagen metabolism, among others. Through a literature review, this study aimed to see the influence of the hormonal changes from the climacteric period in the oral tissues, providing the dentist surgeon with information regarding the consequences and care related to this phase of the woman's life. In this period, women become more susceptible to changes such as: osteopenia and osteoporosis of the jaws, hyposalivation, periodontal diseases, among others. Preventive treatment through removal of plaque, adequacy of the buccal environment and orientation before and during climacteric are the best means of minimizing oral problems arising from this phase of a woman's life.


Assuntos
Humanos , Feminino , Hormônios Esteroides Gonadais , Climatério , Saúde Bucal , Estradiol , Estrogênios
14.
Rev Bras Enferm ; 72(suppl 3): 154-161, 2019 Dec.
Artigo em Inglês, Português | MEDLINE | ID: mdl-31851248

RESUMO

OBJECTIVE: to evaluate the quality of life of primary care nurses in the climacteric. METHOD: A cross-sectional descriptive-analytic study, performed with 98 female nurses, aged 40-65 years, using the WHOQOL-Bref questionnaire. RESULTS: the worst level of quality of life was observed for professionals aged 50-59 years, non-white, specialists, divorced or widowed, with children, a lower income, with another employment relationship, a weekly workload of more than 40 hours, who consumed alcoholic beverages weekly, with chronic disease, in continuous use of medications, sedentary, who did not menstruate and did not receive hormonal treatment, and who went through menopause between the ages of 43-47 years. CONCLUSION: Although the variables "physical activity" and "age" have a statistically significant association with quality of life, other variables seem to interfere in these professionals' lives, indicating the need for a more critical and deep reflection on these relations.


Assuntos
Enfermeiras e Enfermeiros/psicologia , Enfermagem de Atenção Primária/normas , Qualidade de Vida/psicologia , Adulto , Fatores Etários , Idoso , Climatério/psicologia , Grupos de Populações Continentais/estatística & dados numéricos , Estudos Transversais , Feminino , Humanos , Masculino , Menopausa/psicologia , Pessoa de Meia-Idade , Enfermagem de Atenção Primária/métodos , Enfermagem de Atenção Primária/psicologia , Inquéritos e Questionários , Carga de Trabalho/psicologia , Carga de Trabalho/normas
15.
Ann Agric Environ Med ; 26(4): 600-605, 2019 Dec 19.
Artigo em Inglês | MEDLINE | ID: mdl-31885234

RESUMO

OBJECTIVE: The aim of the study was evaluation of the relationship between severity of symptoms of climacteric syndrome, depressive disorders and sleep problems, and the self-rated work ability of peri-menopausal and post-menopausal women in non-manual employment. MATERIAL AND METHODS: The study included 287 women aged 45-60 years, employed in various institutions as non-manual workers. Work Ability Index, Greene Climacteric Scale, Beck Depression Inventory, and Athens Insomnia Scale were used. RESULTS: The examined peri-menopausal and post-menopausal women in non-manual employment obtained good work ability on the Work Ability Index. The severity of menopausal syndrome, according to the Greene Climacteric Scale, was moderate, placing the examined women between results for the general population of women and the pattern for menopausal women. Depressive disorders ranked between low mood and moderate depression. No depression was observed in 59% of the women, whereas moderate depression was observed in 39%, and severe depression in only 2%. Sleep disorders were on the border of normal range. As many as 46% of the women had no sleep problems, which was on the border of normal range in 36%. Only 19% of the examined women suffered from insomnia. Work ability correlated negatively with depression and insomnia severity, as well as with psychological and vasomotor symptoms of climacteric syndrome, but not to its somatic symptoms. CONCLUSIONS: Preventing the occurrence and treatment of menopausal symptoms, sleep and mood disorders may contribute to maintaining the work ability of women in peri- and post-menopausal age.


Assuntos
Climatério/fisiologia , Depressão/fisiopatologia , Perimenopausa/psicologia , Pós-Menopausa/psicologia , Distúrbios do Início e da Manutenção do Sono/fisiopatologia , Climatério/psicologia , Depressão/economia , Depressão/psicologia , Emprego , Feminino , Humanos , Pessoa de Meia-Idade , Perimenopausa/fisiologia , Pós-Menopausa/fisiologia , Distúrbios do Início e da Manutenção do Sono/economia , Distúrbios do Início e da Manutenção do Sono/psicologia , Avaliação da Capacidade de Trabalho
16.
BMC Psychol ; 7(1): 66, 2019 Oct 21.
Artigo em Inglês | MEDLINE | ID: mdl-31639054

RESUMO

BACKGROUND: Recent Life Changes Questionnaire (RLCQ) developed by Richard Rahe has enabled quantification of stress by analyzing life events. The overall aim of the study was to create a reliable version of the Rahe's RLCQ for measuring stress in individuals living in developing countries and assess its validity. This paper discusses criterion validation of the adapted RLCQ in urban communities in Pakistan. METHODS: This is a criterion validation study. Four urban communities of Karachi, Pakistan were selected for the study in which households were randomly chosen. Two data collectors were assigned to administer the adapted RLCQ to eligible participants after obtaining written informed consent. Following this interaction, two psychologists interviewed the same participants with a diagnostic gold standard of Mini International Neuropsychiatric Interview (MINI) which is utilized in usual practice within Pakistan to confirm the presence of stress related mental disorders such as Depression, Anxiety, Dysthymia, Suicide, Phobia, OCD, Panic Disorder, PTSD, Drug abuse and dependence, Alcohol abuse and dependence, Eating Disorders and Antisocial Personality Disorder to validate the accuracy of the adapted RLCQ. We generated the ROC curves for the adapted RLCQ with suggested cut-offs, and analyzed the sensitivity and specificity of the adapted RLCQ. RESULTS: The area under the receiver operating characteristic curve (ROC) of common mental disorders such as depression and anxiety was 0.64, where sensitivity was 66%, specificity was 56% and the corresponding cut off from the adapted RLCQ was 750. Individuals scoring ≥750 were classified as high stress and vice versa. In contrast, the area under the ROC curve for serious mental disorder and adverse outcomes such as suicide, bipolar and dysthymia was 0.75, where sensitivity was 72% and specificity was 60% at the cut off of 800 on the adapted RLCQ. Individuals scoring ≥800 were classified as high stress and vice versa. The rate of agreement between the two psychologists was 94.32% (Kappa = 0.84). CONCLUSION: The adapted and validated RLCQ characterizes common mental disorders such as depression and anxiety with moderate accuracy and severe mental disorders such as suicide, bipolar and dysthymia with high accuracy. TRIAL REGISTRATION: Clinicaltrials.gov NCT02356263 . Registered January 28, 2015. (Observational Study Only).


Assuntos
Climatério/psicologia , Transtornos Mentais/diagnóstico , Estresse Psicológico , Inquéritos e Questionários , Adulto , Ansiedade , Depressão , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Paquistão , Escalas de Graduação Psiquiátrica , Qualidade de Vida , Curva ROC , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , População Urbana
17.
Medicine (Baltimore) ; 98(37): e17039, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31517823

RESUMO

BACKGROUND: Climacteric women experience various disorders, including hot flush, depression, insomnia, arthralgia, and hand and foot numbness. Dangguijakyaksan is among the most common treatments for climacteric syndrome, and its effect on depression, insomnia, hot flush and quality of life (QOL) in climacteric women has been reported multiple times. A recent animal study found dangguijakyaksan decreased serum lipid factors and improved blood circulation in a menopausal rat model; however, these effects have not been assessed in clinical trials. This study aims to assess the clinical effects and safety of dangguijakyaksan for lower-extremity blood circulation disturbances in climacteric women. METHODS: This is a single-center, randomized, double-blinded, placebo-controlled pilot study that will be conducted at Dunsan Korean Medicine Hospital at Daejeon University. Forty-six climacteric women with lower-extremity blood circulation disturbances will be recruited and randomized (1:1) into either the dangguijakyaksan or placebo group. After 8 weeks of administration, the effects and safety of dangguijakyaksan will be assessed.The primary outcome is the visual analogue scale for lower-extremity blood circulation disturbances, and it will be assessed on visits 1, 2, and 3. The secondary outcomes, Kupperman's index and blood deficiency scoring system, will be assessed on visits 1, 2, and 3, and accelerated photoplethysmography and digital infrared thermal imaging will be performed on visits 1 and 3. Moreover, blood lipid profile, follicle-stimulating hormone, and estradiol levels will be measured at the screening visit and visit 3. Blood tests will be performed at the screening visit and visit 3 to assess the safety of dangguijakyaksan. Statistical analysis will be performed using R-3.3.3 (Another Canoe), and within-group study variable differences after drug administration will be analyzed using paired t-test or Wilcoxon signed-rank test. DISCUSSION: We expect to confirm the effects and safety of dangguijakyaksan on lower-extremity blood circulation disturbances in menopause, which would provide foundational data for planning subsequent studies.


Assuntos
Circulação Sanguínea/efeitos dos fármacos , Fármacos Cardiovasculares/uso terapêutico , Climatério , Medicamentos de Ervas Chinesas/uso terapêutico , Ensaios Clínicos Controlados Aleatórios como Assunto , Método Duplo-Cego , Feminino , Humanos , Extremidade Inferior , Pessoa de Meia-Idade , Projetos Piloto
18.
BMC Plant Biol ; 19(1): 369, 2019 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-31438855

RESUMO

BACKGROUND: Cucumis melo is a suitable study material for investigation of fruit ripening owing to its climacteric nature. Long non-coding RNAs have been linked to many important biological processes, such as fruit ripening, flowering time regulation, and abiotic stress responses in plants. However, knowledge of the regulatory roles of lncRNAs underlying the ripening process in C. melo are largely unknown. In this study the complete transcriptome of Cucumis melo L. cv. Hetao fruit at four developmental stages was sequenced and analyzed. The potential role of lncRNAs was predicted based on the function of differentially expressed target genes and correlated genes. RESULTS: In total, 3857 lncRNAs were assembled and annotated, of which 1601 were differentially expressed between developmental stages. The target genes of these lncRNAs and the regulatory relationship (cis- or trans-acting) were predicted. The target genes were enriched with GO terms for biological process, such as response to auxin stimulus and hormone biosynthetic process. Enriched KEGG pathways included plant hormone signal transduction and carotenoid biosynthesis. Co-expression network construction showed that LNC_002345 and LNC_000154, which were highly expressed, might co-regulate with mutiple genes associated with auxin signal transduction and acted in the same pathways. We identified lncRNAs (LNC_000987, LNC_000693, LNC_001323, LNC_003610, LNC_001263 and LNC_003380) that were correlated with fruit ripening and the climacteric, and may participate in the regulation of ethylene biosynthesis and metabolism and the ABA signaling pathway. A number of crucial transcription factors, such as ERFs, WRKY70, NAC56, and NAC72, may also play important roles in the regulation of fruit ripening in C. melo. CONCLUSIONS: Our results predict the regulatory functions of the lncRNAs during melon fruit development and ripening, and 142 highly expressed lncRNAs (average FPKM > 100) were identified. These lncRNAs participate in the regulation of auxin signal transduction, ethylene, sucrose biosynthesis and metabolism, the ABA signaling pathway, and transcription factors, thus regulating fruit development and ripening.


Assuntos
Cucumis melo/genética , Frutas/genética , RNA Longo não Codificante/fisiologia , RNA de Plantas/fisiologia , Mapeamento Cromossômico , Climatério , Cucumis melo/crescimento & desenvolvimento , Frutas/crescimento & desenvolvimento , Perfilação da Expressão Gênica , Genoma de Planta , Fenótipo , Reguladores de Crescimento de Planta/metabolismo , Análise de Sequência de RNA , Transdução de Sinais , Transcriptoma
19.
ScientificWorldJournal ; 2019: 1872536, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31320839

RESUMO

Background: Cardiovascular diseases are leading causes of death worldwide. Recent studies suggest that infection by some viruses, including the human papillomavirus (HPV), may increase the risk of developing atheromatous lesions on coronary arteries. However, there is a lack of data regarding the possible association between HPV infection and coronary artery disease (CAD) in women. Objective: To investigate whether HPV infection is associated with the occurrence of CAD among climacteric women. Methods: The presence of CAD and cervical HPV DNA was investigated in 52 climacteric women. Social and demographic variables and metabolic profiles were also investigated. Results: Among 27 women with CAD, 16 were positive for HPV, whereas 11 were negative. The presence of cervical HPV was strongly associated with CAD, after adjusting for demographic variables, health and sexual behaviors, comorbidities, and known cardiovascular risk factors. HPV-positive women showed a greater likelihood of having CAD (odds ratio [OR] = 3.74; 95% confidence interval [CI]: 1.16 to 11.96) as compared with HPV-negative women, particularly those infected with high-risk HPV types (OR = 4.90; 95% CI: 1.26 to 19.08). Conclusion: These results support the hypothesis that HPV infection might be associated with CAD among climacteric women, though further studies are needed to investigate the mechanisms involved.


Assuntos
Climatério , Doença da Artéria Coronariana/epidemiologia , Doença da Artéria Coronariana/etiologia , Papillomaviridae , Infecções por Papillomavirus/epidemiologia , Adulto , Fatores Etários , Idoso , Feminino , Humanos , Pessoa de Meia-Idade , Razão de Chances , Infecções por Papillomavirus/complicações , Infecções por Papillomavirus/virologia , Vigilância em Saúde Pública , Medição de Risco , Fatores de Risco , Fatores Sexuais , Fatores Socioeconômicos
20.
Rev. enferm. UFSM ; 9: [20], jul. 15, 2019.
Artigo em Português | LILACS, BDENF - Enfermagem | ID: biblio-1024670

RESUMO

Objetivo: identificar nos registros de ocorrência de uma Delegacia Especializada no Atendimento à Mulher (DEAM), as situações de violência perpetradas por parceiro íntimo em abuso de álcool contra mulheres no climatério. Método: pesquisa qualitativa descritiva, realizada na DEAM de um município do interior baiano. Para a coleta de dados, utilizou-se o sistema de notificação de ocorrências da DEAM e na análise dos dados foi empregada a análise de conteúdo. Resultados: a violência praticada por parceiro íntimo torna-se frequente com o uso abusivo de álcool, sob a forma de violência física, psicológica e sexual e na fase do climatério as agressões foram constantes. Considerações finais: ressalta-se a importância da discussão sobre violência contra as mulheres entre profissionais que atuam na atenção primária à saúde para identificar a violência, realizar atendimento integral e implementar estratégias de prevenção e redução da violência, visando à articulação com os serviços da rede de atenção.


Objective: To identify, in the records of a Women's Police Station (Delegacia Especializada no Atendimento à Mulher, DEAM), violence perpetrated by intoxicated intimate partners against women in the climacteric period. Method: A descriptive qualitative research carried out in the DEAM of a municipality in the inland of Bahia. For data collection and analysis, the DEAM's notification system was used and its content was analyzed. Results: Intimate partner violence and alcohol abuse are frequently related; it happens in the form of physical, psychological and sexual violence. During the climacteric period the aggressions were constant. Final considerations: The importance to discuss violence against women among professionals working in primary health care is highlighted to identify violence, provide integral care and implement strategies to prevent and reduce violence, in order to articulate with the services of primary health care.


Objetivo: identificar, en los registros de ocurrencia, de una Delegacia Especializada no Atendimento à Mulher (DEAM), las situaciones de violencia perpetradas por compañeros íntimos en abuso de alcohol contra mujeres en el climaterio. Método: investigación cualitativa, descriptiva, realizada en la DEAM, de un municipio del interior bahiano. Para la recolección de los datos se utilizó el sistema de notificación de ocurrencias de la DEAM y el análisis de los datos se basó en el análisis de contenido. Resultados: la violencia practicada por los compañeros íntimos ocurre frecuentemente con el uso abusivo del alcohol, por la forma de violencia física, psicológica y sexual, en la fase del climaterio las agresiones son constantes. Consideraciones finales: se resalta la importancia de la discusión sobre la violencia contra las mujeres entre profesionales, que actúan en la atención primaria a la salud, para identificar la violencia, realizar atendimiento integral e implementar estrategias de prevención y reducción de la violencia, para la articulación de los servicios de la red de atención.


Assuntos
Humanos , Climatério , Alcoolismo , Violência contra a Mulher , Violência por Parceiro Íntimo
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