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1.
PLoS One ; 15(12): e0243970, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33315932

RESUMO

Assessing chronic pain is a challenge given its subjective dimension. In humans, resting state electroencephalography (EEG) is a promising tool although the results of various studies are contradictory. Spontaneous chronic pain is understudied in animals but could be of the highest interest for a comparative study. Riding horses show a very high prevalence of back disorders thought to be associated with chronic pain. Moreover, horses with known back problems show cognitive alterations, such as a lower attentional engagement. Therefore, we hypothesized that the individual EEG power profiles resting state (i.e. quiet standing) of different horses could reflect the state of their back, that we measured using static sEMG, a tool first promoted to assess lower back pain in human patients. Results show that 1) EEG profiles are highly stable at the intra-individual level, 2) horses with elevated back tension showed resting state EEG profiles characterized by more fast (beta and gamma) and less slow (theta and alpha) waves. The proportion of theta waves was particularly negatively correlated with muscular tension along the spine. Moreover, elevated back tension was positively correlated with the frequency of stereotypic behaviours (an "addictive- like" repetitive behavior) performed by the horses in their stall. Resting state quantitative EEG appears therefore as a very promising tool that may allow to assess individual subjective chronic pain experience, beyond more objective measures of tension. These results open new lines of research for a multi-species comparative approach and might reveal very important in the context of animal welfare.


Assuntos
Dor Crônica/fisiopatologia , Disfunção Cognitiva/fisiopatologia , Eletroencefalografia , Coluna Vertebral/fisiopatologia , Bem-Estar do Animal , Animais , Atenção/fisiologia , Dor Crônica/complicações , Dor Crônica/diagnóstico por imagem , Dor Crônica/veterinária , Disfunção Cognitiva/complicações , Disfunção Cognitiva/diagnóstico por imagem , Feminino , Cavalos/fisiologia , Masculino , Coluna Vertebral/diagnóstico por imagem
2.
Medicine (Baltimore) ; 99(43): e22443, 2020 Oct 23.
Artigo em Inglês | MEDLINE | ID: mdl-33120739

RESUMO

The objectives of this study were to describe the prevalence and characteristics of radiographic lesions of the hands, and calcifications of the spine on computer tomography scans (CT-scans), and to investigate the relationships between radiographic and CT-scan abnormalities and clinical features in a population of patients with systemic sclerosis (SSc).Subjects underwent X-ray examination of the hands, and thoracic or thoraco-abdominal and pelvic CT scan or lumbar CT scan in the year. Structural lesions on hand X ray was scored and spinal calcifications were evaluated in the anterior, intracanal and posterior segments. Intra and inter-reliability was tested for radiography and CT- scan. Prognostic factors considered were interstitial pulmonary lesions on the CT scan, pulmonary arterial hypertension (PAH) and death.This study involved 77 SSc patients, 58 (75%) with limited cutaneous SSc (lcSSc) and 19 (25%) with diffuse SSc (dSSc). The prevalences of radiographic lesions of the hand were 28.6% for periarticular calcifications and 26% for calcinosis. On CT scan, 64 (83%) patients exhibited at least 1 calcification. Spine calcifications were depicted in 80.5%, 27.3%, and 35.1% at the anterior, intracanal and posterior segments respectively. Calcifications were mainly localized on thoracic spine. Inter reader reliabilities were good for hands and moderate for spine respectively. Spine calcifications and periarticular calcifications in the hands were associated (P = .012). Calcinosis in the hands was related to PAH (P = .02). Posterior calcification segment and foraminal calcifications were associated with interstitial lung disease (ILD) (P = .029) and death (P = .001).More than 80% of systemic sclerosis patients presented spine calcifications. A significant association between hands and spinal calcifications were confirmed and some localization in the posterior segment considered as a bad prognostic factor.


Assuntos
Calcinose/diagnóstico por imagem , Ossos da Mão/diagnóstico por imagem , Escleroderma Sistêmico/complicações , Doenças da Coluna Vertebral/diagnóstico por imagem , Coluna Vertebral/diagnóstico por imagem , Fatores Etários , Feminino , Humanos , Hipertensão Pulmonar/complicações , Doenças Pulmonares Intersticiais/complicações , Masculino , Pessoa de Meia-Idade , Prognóstico , Radiografia , Reprodutibilidade dos Testes , Estudos Retrospectivos , Escleroderma Sistêmico/mortalidade , Tomografia Computadorizada por Raios X
3.
Artigo em Inglês | MEDLINE | ID: mdl-33027392

RESUMO

Tuberculosis of the skull or calvarial tuberculosis (CTB) is rare. The literature until 2019 reported less than 60 cases of CTB in childhood. The authors describe two patients with CTB associated with other manifestations of TB, such as: spine and rib injuries, peripheral adenopathy, hepatic and splenic involvement who improved with chemotherapy. The patients were a four-year-old and an eight-year-old child, whose diagnoses were confirmed by histopathological, bacteriological or molecular investigation. Both were not infected with the human immunodeficiency virus (HIV) and did not need orthopedic treatment.


Assuntos
Crânio/diagnóstico por imagem , Teste Tuberculínico/métodos , Tuberculose/diagnóstico , Antituberculosos/uso terapêutico , Criança , Pré-Escolar , Humanos , Coluna Vertebral/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Tuberculose/tratamento farmacológico
4.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 2039-2042, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018405

RESUMO

Scoliosis is a 3D spinal deformation where the spine takes a lateral curvature, which generates an angle in a coronal plane. For periodic detection of scoliosis, safe and economic imaging modality is needed as continuous exposure to radiative imaging may cause cancer. 3D ultrasound imaging is a cost-effective and radiation-free imaging modality which gives volume projection image. Identification of mid-spine line using manual, semi-automatic and automatic methods have been published. Still, there are some difficulties like variations in human measurement, slow processing of data associated with them. In this paper, we propose an unsupervised ground truth generation and automatic spine curvature segmentation using U- Net. This approach of the application of Convolutional Neural Network on ultrasound spine image, to perform automatic detection of scoliosis, is a novel one.


Assuntos
Imageamento Tridimensional , Escoliose , Humanos , Redes Neurais de Computação , Escoliose/diagnóstico por imagem , Coluna Vertebral/diagnóstico por imagem , Ultrassonografia
5.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 2096-2100, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018419

RESUMO

X-ray imaging is currently the gold standard for the assessment of spinal deformities. The purpose of this study is to evaluate a freehand 3D ultrasound system for volumetric reconstruction of the spine. A setup consisting of an ultrasound scanner with a linear transducer, an electromagnetic measuring system and a workstation was used. We conducted 64 acquisitions of US images of 8 adults in a natural standing position, and we tested three setups: 1) Subjects are constrained to be close to a wall, 2) Subjects are unconstrained, and 3) Subjects are constrained to performing fast and slow acquisitions. The spinous processes were manually selected from the volume reconstruction from tracked ultrasound images to generate a 3D point-based model depicting the centerline of the spine. The results suggested that a freehand 3D ultrasound system can be suitable for representing the spine. Volumetric reconstructions can be computed and landmarking can be performed to model the surface of the spine in the 3D space. These reconstructions promise to generate computer-based descriptors to analyze the shape of the spine in the 3D space.Clinical Relevance- We provide clinicians with a protocol that could be integrated in clinical setups for the assessment and monitoring of AIS, based on US image acquisitions, which constitutes a radiation-free technology.


Assuntos
Imageamento Tridimensional , Coluna Vertebral , Adulto , Fenômenos Eletromagnéticos , Humanos , Radiografia , Coluna Vertebral/diagnóstico por imagem , Ultrassonografia
6.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 2101-2104, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018420

RESUMO

Ultrasound (US) imaging technique has been applied to measure the proxy Cobb angle and spinous process angle (SPA) for spinal curvatures of scoliosis. However manual measurement of ultrasound images is time consuming and greatly relying on the experience of raters. The objectives of this work are to develop an automatic measurement method to assess SPA of spine curves and to evaluate the accuracy and reliability of the method. The spinous process curves were identified and fitted on US images, and the automatically measured SPA were compared with the results from US manual and radiographic measurements. It illustrates that the US-auto measurement of SPA presents higher correlation and smaller difference with clinical standard radiographic results than the US-manual measurement.


Assuntos
Escoliose , Curvaturas da Coluna Vertebral , Humanos , Reprodutibilidade dos Testes , Escoliose/diagnóstico por imagem , Coluna Vertebral/diagnóstico por imagem , Ultrassonografia
7.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 2105-2108, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018421

RESUMO

The 3D ultrasound reconstruction technology has led to a rapid development of ultrasound spine imaging in recent decades. However, the current imaging apparatus is bulky and not portable. The objective of this study is to develop a new compact and wireless system to offer the real-time visualized spine images during data acquisition. A portable and WI-FI based ultrasound scanner and a compact EM tracking system were assembled to acquire ultrasound transverse frames with location information which could be reconstructed into 3D spine image volume in real-time. The validation was implemented on the 2D coronal images of vertebra phantoms, and the in vivo data acquisition and reconstruction were demonstrated on volunteers. The result showed that the new system could provide reconstructed spine images in real time and the average errors of the reconstructed images were about 1mm (approximate to image pixel size).


Assuntos
Algoritmos , Coluna Vertebral , Humanos , Imageamento Tridimensional , Projetos Piloto , Coluna Vertebral/diagnóstico por imagem , Ultrassonografia
8.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 4030-4033, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018883

RESUMO

Spine Curvature Disorder (SCD) is a medical condition that affects the shape of the spine. Methods of monitoring SCDs involve visual inspection followed by X-rays and measurements. Once a patient is diagnosed with SCD and treatment or therapy is implemented, progress is tracked by exposing the patient to multiple periodic X-rays to determine the spine responses to treatments or therapies. Multiple exposures to X-rays is not desirable and is also costly. Therefore, we propose a new method for detecting and monitoring SCD and present our initial research results. We are implementing a non-invasive method that can detect and monitor the spinal postures of SCD. Magnets are placed on a shirt a grid form then a sensor system would be placed on the chest of the body. An on-body magnetic sensor records the sensor data values to determine if the upper body posture is straight or is curved which in turn can assist in detecting if the spine is deformed. We present our initial results on magnetic sensor testing and preliminary results using wearable sensors and a garment integrated magnetic shirt.


Assuntos
Postura , Dispositivos Eletrônicos Vestíveis , Vestuário , Humanos , Fenômenos Magnéticos , Coluna Vertebral/diagnóstico por imagem
9.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 1633-1636, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018308

RESUMO

Most deep learning based vertebral segmentation methods require laborious manual labelling tasks. We aim to establish an unsupervised deep learning pipeline for vertebral segmentation of MR images. We integrate the sub-optimal segmentation results produced by a rule-based method with a unique voting mechanism to provide supervision in the training process for the deep learning model. Preliminary validation shows a high segmentation accuracy achieved by our method without relying on any manual labelling.The clinical relevance of this study is that it provides an efficient vertebral segmentation method with high accuracy. Potential applications are in automated pathology detection and vertebral 3D reconstructions for biomechanical simulations and 3D printing, facilitating clinical decision making, surgical planning and tissue engineering.


Assuntos
Aprendizado Profundo , Imagem por Ressonância Magnética , Impressão Tridimensional , Coluna Vertebral/diagnóstico por imagem
11.
S Afr Med J ; 110(8): 767-776, 2020 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-32880305

RESUMO

Spinal deformities are common in people with cerebral palsy (CP), and there is a concern of an increase during the adult ageing period. There is especially a worry about the increase of scoliosis, thoracic hyperkyphosis, lumbar hyperlordosis, spondylolysis and spondylolisthesis incidence, though supporting literature is lacking. Therefore, the aim of this narrative review is to provide a scientific overview of how spinal curvatures should be measured, what the norm values are and the incidence in people with CP, as well as a description of the risk factors and the treatment regimens for these spinal abnormalities. This review can be used as a guideline relevant for a range of clinicians, including orthopaedic and neurosurgeons, radiologists, physiotherapists, and biokineticists, as well as academics.


Assuntos
Paralisia Cerebral/complicações , Doenças da Coluna Vertebral/complicações , Humanos , Incidência , Radiografia , Fatores de Risco , Doenças da Coluna Vertebral/diagnóstico , Doenças da Coluna Vertebral/terapia , Coluna Vertebral/diagnóstico por imagem
13.
PLoS One ; 15(9): e0239534, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32966306

RESUMO

In vivo micro-CT has already been used to monitor microstructural changes of bone in mice of different ages and in models of age-related diseases such as osteoporosis. However, as aging is accompanied by frailty and subsequent increased sensitivity to external stimuli such as handling and anesthesia, the extent to which longitudinal imaging can be applied in aging studies remains unclear. Consequently, the potential of monitoring individual mice during the entire aging process-from healthy to frail status-has not yet been exploited. In this study, we assessed the effects of long-term in vivo micro-CT imaging-consisting of 11 imaging sessions over 20 weeks-on hallmarks of aging both on a local (i.e., static and dynamic bone morphometry) and systemic (i.e., frailty index (FI) and body weight) level at various stages of the aging process. Furthermore, using a premature aging model (PolgA(D257A/D257A)), we assessed whether these effects differ between genotypes. The 6th caudal vertebrae of 4 groups of mice (PolgA(D257A/D257A) and PolgA(+/+)) were monitored by in vivo micro-CT every 2 weeks. One group was subjected to 11 scans between weeks 20 and 40 of age, whereas the other groups were subjected to 5 scans between weeks 26-34, 32-40 and 40-46, respectively. The long-term monitoring approach showed small but significant changes in the static bone morphometric parameters compared to the other groups. However, no interaction effect between groups and genotype was found, suggesting that PolgA mutation does not render bone more or less susceptible to long-term micro-CT imaging. The differences between groups observed in the static morphometric parameters were less pronounced in the dynamic morphometric parameters. Moreover, the body weight and FI were not affected by more frequent imaging sessions. Finally, we observed that longitudinal designs including baseline measurements at young adult age are more powerful at detecting effects of in vivo micro-CT imaging on hallmarks of aging than cross-sectional comparisons between multiple groups of aged mice subjected to fewer imaging sessions.


Assuntos
Senilidade Prematura/diagnóstico por imagem , Doenças Ósseas Metabólicas/diagnóstico por imagem , Fragilidade/diagnóstico por imagem , Fatores Etários , Senilidade Prematura/genética , Animais , Doenças Ósseas Metabólicas/genética , Polimerase do DNA Mitocondrial/genética , Modelos Animais de Doenças , Feminino , Fragilidade/genética , Genótipo , Camundongos , Camundongos Mutantes , Proteínas Mutantes/genética , Mutação , Coluna Vertebral/diagnóstico por imagem , Microtomografia por Raio-X
14.
Clinics (Sao Paulo) ; 75: e1824, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32935824

RESUMO

OBJECTIVES: The recent advancements in spine fixation aid in the treatment of complex spinal pathologies. Both the iliac screw (IS) and the S2-alar-iliac (S2AI) screw provide adequate stability in the fixation of complex lumbosacral spine pathologies, leading to a significant increased rate of using these techniques in the daily practice of the spine surgeons. This study aims to analyze, describe, and compare the insertion and positioning parameters of the S2AI screw and IS techniques in children without spinal deformities. METHODS: An observational retrospective study was conducted at a university hospital in 2018, with 25 computed tomography (CT) images selected continuously. Mann-Whitney-Shapiro-Wilk tests were performed. The reliability of the data was assessed using the intraclass correlation. The data were stratified by age group only for Pearson's correlation analysis. RESULTS: The mean age was 11.7 years (4.5 SD). The mean IS length was 106.63 mm (4.59 SD). The mean length of the S2AI screw was 104.13 mm (4.22 SD). The mean skin distance from the IS entry point was 28.13 mm (4.27 SD) and that for the S2AI screw was 39.96 mm (4.54 SD). CONCLUSIONS: Through CT, the S2AI screw trajectory was observed to have a greater bone thickness and skin distance than the IS. There was a linear correlation between age and screw length for both techniques. A similar relationship was observed between skin distance and age for the S2AI screw technique. In children, the S2AI screw technique presents advantages such as greater cutaneous coverage and implant thickness than the IS technique.


Assuntos
Parafusos Ósseos , Fixação Interna de Fraturas/instrumentação , Sacro , Fusão Vertebral/métodos , Coluna Vertebral/diagnóstico por imagem , Criança , Humanos , Reprodutibilidade dos Testes , Estudos Retrospectivos , Fusão Vertebral/instrumentação , Coluna Vertebral/cirurgia , Tomografia Computadorizada por Raios X , Resultado do Tratamento
15.
Orthopade ; 49(10): 849-859, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32944784

RESUMO

The field of musculoskeletal diagnostics and personalized medicine has undergone a revolutionary transformation due to a deeper understanding of skeletal biomechanics and due to technological advancements. Analogous to this transformation, our understanding of spinopelvic conditions has experienced a paradigm shift in terms of both static and dynamic changes in spinopelvic pathologies and enabled a more accurate delineation of the drivers of disability. The purpose of this review is to describe the standard and state of the art of preoperative diagnostic and planning methods for common spinopelvic pathologies and to discuss both the added clinical value and limitations. The rationale is to accelerate the accurate and timely diagnosis and as well as the efficient and safe preoperative workflow.


Assuntos
Pelve/diagnóstico por imagem , Coluna Vertebral/diagnóstico por imagem , Humanos , Pelve/patologia , Período Pré-Operatório , Coluna Vertebral/patologia
16.
Arch Osteoporos ; 15(1): 142, 2020 09 12.
Artigo em Inglês | MEDLINE | ID: mdl-32918631

RESUMO

T-score discordance between hip and spine is a common problem in the diagnosis of osteoporosis based on dual-energy X-ray absorptiometry. Not much information on the prevalence and risk factors of this problem is available in Malaysia. Our study found that factors like age, height, physical activity and menopausal status should be taken into account in the diagnosis of osteoporosis. INTRODUCTION AND OBJECTIVE: T-score discordance between hip and spine is a common problem in bone mineral density assessment. A difference ≥ 1 standard deviation (SD) (regardless of diagnostic class) is considered minor, and a difference more than one diagnostic class is considered major discordance. This study aimed to determine the prevalence and factors of hip and spine T-score discordance in a population aged ≥ 40 years in Klang Valley, Malaysia. SUBJECTS AND METHODS: In this cross-sectional study, subjects answered a demographic questionnaire and underwent body composition and bone health assessment using dual-energy X-ray absorptiometry. Chi-square and binary logistic regression analysis were used to assess the prevalence of T-score discordance among the subjects. RESULTS: A total of 786 Malaysians (382 men, 404 women) subjects were recruited. The prevalence of minor and major discordance was 30.3% and 2.3%, respectively. Overall, factors related to T-score discordance were advanced age, decreased height, and being physically active. Sub-analysis showed that decreased height and being physically active predicted T-score discordance in men, being menopausal and Indian (vs Chinese) were predictors in women. CONCLUSIONS: T-score discordance between hip and spine is common among Malaysian middle-aged and elderly population. Diagnosis of osteopenia/osteoporosis should be based on the T-score of more than one skeletal site as per the current recommendations.


Assuntos
Absorciometria de Fóton/métodos , Densidade Óssea/fisiologia , Osteoporose/diagnóstico , Coluna Vertebral/diagnóstico por imagem , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Humanos , Malásia/epidemiologia , Masculino , Pessoa de Meia-Idade , Osteoporose/epidemiologia , Prevalência
17.
Eur. j. anat ; 24(5): 439-448, sept. 2020. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-195281

RESUMO

The aim of this study is to describe the anatomical alterations in complementary tests (MRI and EMG) in patients with cervicobrachialgia according to sex and age. Retrospective study of 184 patients with cervicobrachialgia who underwent cervical MRI and EMG. The variables analyzed were gender, age, elements of spondylosis (osteophytes, arthropathy, spondylolisthesis and canal stenosis), the type of disc disease (protrusion and herniated disc) and curvature in the sagittal plane. The EMG was used to evaluate the neurogenic findings in the muscles dependent on the spinal roots of C4 to C8-T1.Average age was 53.65±11.96 years. The patients were evaluated for the presence of osteophytes (n = 111), arthropathy (n = 76), spondylolisthesis (n = 15) and stenosis of the spinal canal (n = 35). The highest incidences were osteophytes in C5-C6 (n = 108), protrusions in C5-C6 (n = 58), herniated disc in C5-C6 (n=18) and neurogenic findings in C7 (n = 130). The rectification of cervical lordosis appeared in 124 patients.S pondylosis increases with age. Disc herniations, disc protrusions and motor radiculopathy are more frequent in the 5th to 6th years of life. In patients with cervicobrachialgia, the sagittal rectification is more common than the normal lordosis


No disponible


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Espondilose/diagnóstico por imagem , Coluna Vertebral/anatomia & histologia , Coluna Vertebral/diagnóstico por imagem , Coluna Vertebral/patologia , Estudos Retrospectivos , Radiculopatia/diagnóstico por imagem
18.
Br J Radiol ; 93(1114): 20200565, 2020 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-32783630

RESUMO

OBJECTIVES: To investigate via computer simulation, an optimised tube voltage (kVp) range for caesium iodide (CsI)-based digital radiography (DR) of the abdomen, pelvis and lumbar spine. METHODS: Software capable of simulating abdomen, pelvis and spine radiographs was used. Five evaluators graded clinical image criteria in images of 20 patients at tube voltages ranging from 60 to 120 kVp in 10 kVp increments. These criteria were scored blindly against the same patient reconstructed at a specific reference kVp. Linear mixed effects analysis was used to evaluate image scores for each criterion and test for statistical significance. RESULTS: Score was dependent on tube voltage and image criteria; both were statistically significant. All criteria for all anatomies scored very poorly at 60 kVp. Scores for abdomen, pelvis and spine imaging peaked at 70, 70 and 100 kVp, respectively, but other kVp values were not significantly poorer. CONCLUSIONS: Results indicate optimum tube voltages of 70 kVp for abdomen and pelvis (with an optimum range 70-120 kVp), and 100 kVp (optimum range 80-120 kVp) for lumbar spine. ADVANCES IN KNOWLEDGE: There are no recommendations for optimised tube voltage parameters for DR abdomen, pelvis or lumbar spine imaging. This study has investigated and recommended an optimal tube voltage range.


Assuntos
Abdome/diagnóstico por imagem , Pelve/diagnóstico por imagem , Intensificação de Imagem Radiográfica/métodos , Coluna Vertebral/diagnóstico por imagem , Algoritmos , Césio , Simulação por Computador , Humanos , Iodetos , Imagens de Fantasmas , Interpretação de Imagem Radiográfica Assistida por Computador , Software
19.
BMJ Case Rep ; 13(8)2020 Aug 11.
Artigo em Inglês | MEDLINE | ID: mdl-32784242

RESUMO

A 60-year-old man presented to hospital with bilateral lower limb weakness, urinary retention and constipation. He had been diagnosed with COVID-19 10 days prior. Clinical examination revealed global weakness, increased tone, hyperreflexia and patchy paresthesia in his lower limbs bilaterally. Preliminary blood tests performed revealed a mildly elevated C reactive protein and erythrocyte sedimentation rate but was otherwise unremarkable. MRI scan of his whole spine demonstrated hyperintense T2 signal centrally from T7 to T10, suggestive of acute transverse myelitis. A lumbar puncture showed elevated protein count but normal glucose and white blood cell count. Serological testing for other viruses was negative. His neurological symptoms improved significantly after treatment with intravenous methylprednisone. This case highlights a potential neurological complication of COVID-19 infection.


Assuntos
Betacoronavirus , Infecções por Coronavirus/complicações , Mielite Transversa/diagnóstico por imagem , Mielite Transversa/etiologia , Pneumonia Viral/complicações , Doença Aguda , Diagnóstico Diferencial , Glucocorticoides/uso terapêutico , Humanos , Imagem por Ressonância Magnética/métodos , Masculino , Metilprednisolona/uso terapêutico , Pessoa de Meia-Idade , Mielite Transversa/tratamento farmacológico , Pandemias , Coluna Vertebral/diagnóstico por imagem
20.
Arch Osteoporos ; 15(1): 132, 2020 08 18.
Artigo em Inglês | MEDLINE | ID: mdl-32812073

RESUMO

The osteoporosis self-assessment tool was more accurate than hand grip strength, gait speed, and calf circumference in predicting osteoporosis in women. Hand grip strength was more accurate than the osteoporosis self-assessment tool, gait speed, and calf circumference in predicting osteoporosis in men. PURPOSE: The osteoporosis self-assessment tool, functional assessment, and anthropometric measurement are different techniques to identify those at risk of osteoporosis. This study aimed to compare the performance of these techniques in predicting osteoporosis. METHODS: In this cross-sectional, hospital-based study including 1109 participants, the bone mineral density of the spine and hips was evaluated using the dual-energy X-ray absorptiometry. The Osteoporosis Self-Assessment Tool was used as a simple clinical risk assessment tool to screen for osteoporosis. Gait speed and hand grip strength were used as functional assessments to predict osteoporosis. Calf circumference was used as an anthropometric measurement to predict osteoporosis risk. RESULTS: In women, the Osteoporosis Self-Assessment Tool was better than hand grip strength, gait speed, and calf circumference in predicting osteoporosis. In contrast, in men, hand grip strength was better than the Osteoporosis Self-Assessment Tool, gait speed, and calf circumference. CONCLUSION: The application of simple, cost-effective techniques for the identification of osteoporosis risk will be beneficial for both screening and patient care when dual-energy X-ray absorptiometry is not available. We suggest that the Osteoporosis Self-Assessment Tool can be used to identify the risk of osteoporosis in women and hand grip strength measurement can be used for men.


Assuntos
Absorciometria de Fóton/métodos , Antropometria , Densidade Óssea/fisiologia , Força da Mão , Programas de Rastreamento/métodos , Osteoporose/diagnóstico por imagem , Medição de Risco/métodos , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Autoavaliação Diagnóstica , Feminino , Marcha/fisiologia , Quadril/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Autoavaliação , Coluna Vertebral/diagnóstico por imagem , Velocidade de Caminhada
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