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1.
Niger J Clin Pract ; 23(11): 1548-1554, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-33221780

RESUMO

Objective: The relationship between sexual functions and infertility remains controversial and there is a limited number of studies reporting the effects of infertility on sexual functions in women with polycystic ovary syndrome (PCOS). Aims: The present study aims to investigate the effects of infertility on sexual functions and depression levels in women with PCOS. Methods: A total of 150 participants who were either fertile patients with PCOS, infertile patients with PCOS, or fertile women without PCOS (control) (n = 50) were included for the study. Sociodemographic data were recorded and the Female Sexual Function Index (FSFI) and Beck Depression Inventory (BDI) were used for evaluation of subjects. Results: Body mass index (BMI) was found to be significantly higher in the PCOS plus infertility group (27.9 ± 2.9, P = 0.01) than the other groups. Total BDI score was higher and total FSFI score was significantly lower in the PCOS plus infertility group than in the other groups. The PCOS plus infertility group showed significantly lower FSFI scores than the PCOS group in terms of desire, lubrication, orgasm, satisfaction, and pain. A significant negative correlation was observed between BMI and BDI scores in the PCOS plus infertility group (r:-0.384, P = 0.04). Conclusion: Our study results show lower sexual functions in PCOS women with infertility and that infertility negatively affects sexual functions with obesity associated depression.


Assuntos
Obesidade/psicologia , Síndrome do Ovário Policístico/complicações , Qualidade de Vida , Comportamento Sexual/fisiologia , Disfunções Sexuais Fisiológicas/etiologia , Adulto , Índice de Massa Corporal , Estudos de Casos e Controles , Depressão/etiologia , Depressão/psicologia , Feminino , Humanos , Infertilidade Feminina , Libido/fisiologia , Orgasmo , Satisfação Pessoal , Síndrome do Ovário Policístico/psicologia , Comportamento Sexual/psicologia , Disfunções Sexuais Fisiológicas/psicologia , Turquia/epidemiologia
2.
Afr J AIDS Res ; 19(3): 249-262, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33119459

RESUMO

Reducing multiple and concurrent partnerships has been identified as a priority in generalised HIV epidemics, yet developing successful interventions to bring about such behaviour change has proven challenging. We offered a three-session intervention aimed to improve couple relationship quality and address HIV risk factors, particularly concurrent sexual partnerships (CSP), in a peri-urban community of Kampala, Uganda. Before launching the intervention, a different group of community members participated in eight single-gender focus group discussions (FGDs) which explored issues of couple relationship quality and satisfaction. Findings from the FGDs guided the intervention. All 162 couples invited to the intervention completed a survey pre- and post-intervention. In FGDs, women and men discussed challenges faced in their relationships, including pervasive dissatisfaction, financial constraints, deception and lack of trust, poor communication, lack of sexual satisfaction, and concurrent sexual partnerships. A difference-in-difference analysis showed no measurable impact of the intervention on relationship quality or sexual risk behaviours over a six-month follow-up among 183 individuals who participated in the intervention, although many stated in response to open-ended questions that they had experienced positive relationship changes. Qualitative findings suggest high demand for couple-focused interventions but also reveal many individual-, couple-, community- and structural-level factors which contribute to women and men seeking concurrent sexual partnerships. More intensive interventions may be needed to overcome these barriers to behaviour change and reduce HIV risk. These findings also raise questions about how to interpret divergent qualitative and quantitative data, a topic which has received little attention in the literature.


Assuntos
Infecções por HIV/prevenção & controle , Infecções por HIV/psicologia , Relações Interpessoais , Parceiros Sexuais , Adulto , Feminino , Grupos Focais , Infecções por HIV/epidemiologia , Humanos , Masculino , Fatores de Risco , Comportamento Sexual/fisiologia , Parceiros Sexuais/psicologia , População Suburbana , Uganda/epidemiologia
3.
PLoS One ; 15(9): e0238706, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32915820

RESUMO

The aim of the present study was to determine the level of morphological asymmetry among the general population of Polish youth as it correlates to sex and body type. The anthropometric characteristics of a group of 618 Polish youths (354 males aged 19.5 ± 1.2 years and 264 females aged 19.2 ± 1.2 years) were evaluated to assess their somatotypes using the Heath-Carter method. Body composition was calculated using the bioelectrical impedance method, and the absolute asymmetry index was used for comparisons between the right and left sides of the body. Significant differentiation was observed between all morphological characteristics (≤ 0.0001) and two body types (≤ 0.0001) among sexes. Females and males largely exhibited endomorphic and mesomorphic somatotypes, respectively. The findings demonstrated that dominant somatotype and sex both affect the level of fat mass asymmetry in the arms and legs. Furthermore, significant variations in the levels of asymmetry between sexes were observed in fat mass in both the arms and legs, with greater variation observed in the arms. In the case of muscle mass, no great differences were observed between men, women, or body types. This study provides new data on the morphological asymmetry of given body composition according to somatotype and sex. This study has potential medical implications, given that a large degree of inter-limb imbalance could be shown to have a negative effect on health; the findings of the present study would therefore be important for arriving at an understanding of how to prevent such imbalances, or to mitigate their negative effects.


Assuntos
Composição Corporal/fisiologia , Comportamento Sexual/fisiologia , Somatotipos/fisiologia , Adolescente , Adulto , Antropometria , Impedância Elétrica , Feminino , Humanos , Masculino , Polônia/epidemiologia , Comportamento Sexual/psicologia , Somatotipos/psicologia , Adulto Jovem
4.
Lancet Diabetes Endocrinol ; 8(8): 693-702, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32707117

RESUMO

BACKGROUND: Although clinicians often measure the serum concentration of androgens in premenopausal women presenting with sexual dysfunction, with some women given testosterone or dehydroepiandrosterone as treatment if their concentrations are low, whether androgens are determinants of sexual function in women of reproductive age is uncertain. We aimed to clarify the associations between androgens and sexual function in a community-based sample of non-health-care-seeking women. METHODS: This is a substudy of the Grollo-Ruzzene cross-sectional study, which recruited women aged 18-39 years from eastern states in Australia (QLD, NSW, VIC). After providing consent, women completed an online survey that included the Profile of Female Secual Function (PFSF) questionnaire, and those who were who were not pregnant, breastfeeding, or using systemic steroids were asked to provide a blood sample. At sampling, women were asked the dates of their last menstrual bleed. Serum androgens was measured by liquid chromatography and tandem mass spectrometry and sex hormone binding globulin (SHBG) by immunoassay. Associations between androgens and domains of sexual function, assessed by the PFSF, were examined in participants with regular menstrual cycles. After univariable linear regression (model 1), age, BMI, stage of menstrual cycle, and smoking status were added to the model (model 2), and then parity, partner status, and psychotropic medication use (model 3). FINDINGS: Of 6986 women who completed the online survey (surveys completed between Nov 11, 2016, and July 21, 2017), 3698 were eligible and 761 (20·6%) provided blood samples by Sept 30, 2017. Of those who provided a blood sample, 588 (77·3%) had regular menstrual cycles and were included in the analysis. Adjusting for age, BMI, cycle stage, smoking, parity, partner status, and psychoactive medication, sexual desire was positively associated with serum dehydroepiandrosterone (ß-coefficient 3·39, 95% CI 0·65 to 6·03) and androstenedione (4·81, 0·16 to 9·12), and negatively with SHBG (-5.74, -9.54 to -1·90), each model explaining less than 4% of the variation in desire. Testosterone (6·00, 1·29 to 10·94) and androstenedione (6·05, 0·70 to 11·51) were significantly associated with orgasm, with the final models explaining less than 1% of the variation in orgasm. Significant associations were found between androstenedione (7·32, 0·93 to 13·08) and dehydroepiandrosterone (4·44, 0·86 to 7·95) and pleasure, and between testosterone and sexual self-image 5·87 (1·27 to 10·61), with inclusion of parity, partners status, and psychotropic drug use increasing the proportion of variation explained by each model to approximately 10%. There were no statistically significant associations between 11-oxygenated steroids and any PFSF domain, or between arousal or responsiveness and any hormone. No associations were seen between 11-oxygenated steroids and any sexual domain, or between arousal or responsiveness and any hormone. INTERPRETATION: Associations between androgens and sexual function in premenopausal women are small, and their measurement offers no diagnostic use in this context. Further research to determine whether 11-ketoandrostenedione or 11-ketotestosterone are of clinical significance is warranted. FUNDING: The Grollo-Ruzzene Foundation.


Assuntos
Androgênios/sangue , Pré-Menopausa/sangue , Comportamento Sexual/fisiologia , Adolescente , Adulto , Austrália/epidemiologia , Estudos Transversais , Feminino , Humanos , Disfunções Sexuais Fisiológicas/sangue , Disfunções Sexuais Fisiológicas/diagnóstico , Disfunções Sexuais Fisiológicas/epidemiologia , Adulto Jovem
5.
Rev Lat Am Enfermagem ; 28: e3293, 2020.
Artigo em Inglês, Português, Espanhol | MEDLINE | ID: mdl-32578751

RESUMO

OBJECTIVE: to investigate female sexual function in women six months postpartum and to compare sexual function among women who had and who did not have severe maternal morbidity (SMM). METHOD: a cross-sectional study conducted with 110 women in the postpartum period, with and without SMM. Two instruments were used, one for the characterization of sociodemographic and obstetric variables and the Female Sexual Function Index (FSFI) for sexual function. Univariate, bivariate and regression model analyses were performed. RESULTS: FSFI scores showed 44.5% of female sexual dysfunction, of which 48.7% were among women who had SMM and 42.0% among those who had not. There were significant differences between age (P=0.013) and duration of pregnancy (P<0.001) between women with or without SMM. Among the cases of SMM, hypertensive disorders were the most frequent (83%). An association was obtained between some domains of the FSFI and the following variables: orgasm and self-reported skin color, satisfaction and length of relationship, and pain and SMM. CONCLUSION: white women have greater difficulty in reaching orgasm when compared to non-white women and women with more than 120 months of relationship feel more dissatisfied with sexual health than women with less time in a relationship. Women who have had some type of SMM have more dyspareunia when compared to women who have not had SMM.


Assuntos
Satisfação Pessoal , Período Pós-Parto/fisiologia , Comportamento Sexual/fisiologia , Adulto , Estudos Transversais , Feminino , Humanos , Período Pós-Parto/psicologia , Comportamento Sexual/psicologia , Saúde Sexual , Sexualidade , Fatores Socioeconômicos , Inquéritos e Questionários
6.
Proc Biol Sci ; 287(1928): 20200805, 2020 06 10.
Artigo em Inglês | MEDLINE | ID: mdl-32517615

RESUMO

Mate choice can continue after mating via chemical communication between the female reproductive system and sperm. While there is a growing appreciation that females can bias sperm use and paternity by exerting cryptic female choice for preferred males, we know surprisingly little about the mechanisms underlying these post-mating choices. In particular, whether chemical signals released from eggs (chemoattractants) allow females to exert cryptic female choice to favour sperm from specific males remains an open question, particularly in species (including humans) where adults exercise pre-mating mate choice. Here, we adapt a classic dichotomous mate choice assay to the microscopic scale to assess gamete-mediated mate choice in humans. We examined how sperm respond to follicular fluid, a source of human sperm chemoattractants, from either their partner or a non-partner female when experiencing a simultaneous or non-simultaneous choice between follicular fluids. We report robust evidence under these two distinct experimental conditions that follicular fluid from different females consistently and differentially attracts sperm from specific males. This chemoattractant-moderated choice of sperm offers eggs an avenue to exercise independent mate preference. Indeed, gamete-mediated mate choice did not reinforce pre-mating human mate choice decisions. Our results demonstrate that chemoattractants facilitate gamete-mediated mate choice in humans, which offers females the opportunity to exert cryptic female choice for sperm from specific males.


Assuntos
Óvulo , Comportamento Sexual/fisiologia , Feminino , Células Germinativas , Humanos , Masculino , Reprodução , Espermatozoides
7.
Int J Nurs Pract ; 26(3): e12855, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32510741

RESUMO

AIM: This study aimed to determine the effects of a postpartum sexual health education programme structured according to Levine's conservation model on postpartum women. METHODS: The interventional study was completed with 67 postpartum women. The intervention group was given the postpartum sexual health education programme structured according to Levine's conservation model. The control group received routine discharge training. The data were collected using a personal information form, The Index of Female Sexual Function, Arizona Sexual Experience Scale and Golombok-Rust Inventory of Sexual Satisfaction. RESULTS: It has been determined that the decrease in sexual arousal and desire is the first among postpartum sexual problems experienced by women. This study demonstrated that sexual function, sexual satisfaction and sexual response were higher in nonbreastfeeding women, women who had sexual intercourse one to three times a week and women who could talk to health care professionals on sexual matters. After the programme, the intervention group had more adequate sexual function, and they developed a strong, easy and satisfactory sexual response than the control group (p < 0.05). CONCLUSION: This programme was effective in increasing the sexual functions and satisfaction of the postpartum women. Models provide guidance to nurses for provision of care in a systematic manner.


Assuntos
Educação em Saúde/normas , Cuidado Pós-Natal , Saúde Sexual/educação , Adulto , Feminino , Educação em Saúde/organização & administração , Humanos , Satisfação Pessoal , Gravidez , Comportamento Sexual/fisiologia , Adulto Jovem
8.
Arch Sex Behav ; 49(5): 1517-1532, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32504234

RESUMO

Sexual concordance-the agreement between physiological (genital) and psychological (emotional) sexual arousal-is, on average, substantially lower in women than men. Following social role theory, the gender difference in sexual concordance may manifest because women and men are responding in a way that accommodates gender norms. We examined genital and self-reported sexual arousal in 47 women and 50 men using a condition known to discourage conformity to gender norms (i.e., a bogus pipeline paradigm). Participants reported their feelings of sexual arousal during a sexually explicit film, while their genital arousal (penile circumference, vaginal vasocongestion), heart rate (HR), and galvanic skin (GS) responses were recorded. Half of the participants were instructed that their self-reported sexual arousal was being monitored for veracity using their HR and GS responses (bogus pipeline condition; BPC); the remaining participants were told that these responses were recorded for a comprehensive record of sexual response (typical testing condition; TTC). Using multi-level modeling, we found that only women's sexual concordance was affected by testing condition; women in the BPC exhibited significantly higher sexual concordance than those in the TTC. Thus, we provide the first evidence that the gender difference in sexual concordance may at least partially result from social factors.


Assuntos
Nível de Alerta/fisiologia , Frequência Cardíaca/fisiologia , Comportamento Sexual/fisiologia , Adolescente , Adulto , Feminino , Humanos , Masculino , Autorrelato , Adulto Jovem
9.
Cardiovasc Intervent Radiol ; 43(8): 1202-1207, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32494835

RESUMO

INTRODUCTION: The effect of prostate artery embolization (PAE) on male sexual function is currently the subject of debate in the literature. The main purpose of this study was to define changes in all domains of sexual activity after PAE, using the international index of erectile function score (IIEF-15). METHODS: A single-center retrospective study was conducted on 129 patients (mean age of 65.5 ± 7 years), who underwent PAE from February 2014 to January 2017 for symptomatic benign prostatic hyperplasia (BPH). Fifty consecutive patients fulfilling the inclusion criteria were evaluated before and after PAE follow-up using the IIEF-15, IPSS, prostate volume (PV) and cardiovascular risk factor and BPH drugs. The IIEF-15 domains analyzed were: erectile function (EF) ejaculation and orgasm (Ej/O), sexual desire (SD), intercourse satisfaction (IS) and overall satisfaction (OS). A paired sample t test or Wilcoxon signed-rank test was used to compare IIEF-15 between baseline and follow-up. RESULTS: The study showed nonsignificant change in IIEF-15 total score (58.0 ± 13.8 SD; p = 0.71) and the five domains (EF 24.5 ± 7.0 SD, p = 0.82; EJ/O 8.2 ± 2.3 SD, p = 0.50; SD 7.2 ± 2.7 SD, p = 0.57; IS 10.3 ± 3.0 SD, p = 0.77; OS 8.2 ± 2.7 SD; p = 0.11) after PAE. We also found a significant improvement in IPSS score after PAE. CONCLUSION: Based on the IIEF-15 questionnaire, PAE was showed to allow good urinary symptoms results and no deterioration in sexual function.


Assuntos
Embolização Terapêutica/métodos , Disfunção Erétil/prevenção & controle , Sintomas do Trato Urinário Inferior/etiologia , Sintomas do Trato Urinário Inferior/terapia , Hiperplasia Prostática/complicações , Hiperplasia Prostática/terapia , Idoso , Idoso de 80 Anos ou mais , Humanos , Masculino , Pessoa de Meia-Idade , Próstata/irrigação sanguínea , Estudos Retrospectivos , Comportamento Sexual/fisiologia , Inquéritos e Questionários , Resultado do Tratamento
10.
Clín. investig. ginecol. obstet. (Ed. impr.) ; 47(2): 40-50, abr.-jun. 2020. graf, tab
Artigo em Espanhol | IBECS | ID: ibc-193717

RESUMO

OBJETIVO: El posible impacto de la histerectomía sobre la función sexual genera ansiedad a las mujeres. Los estudios han mostrado controversia. Dada la frecuencia de esta intervención, nuestro objetivo es saber si la función sexual cambia tras la misma. MATERIAL Y MÉTODOS: Comparamos la función sexual antes de la histerectomía, a los 3 meses tras la misma y a los 9 meses, de las 299 mujeres a las que se les programa dicha intervención entre el 1 de noviembre de 2012 y el 31 de noviembre de 2014 en el Complejo Hospitalario Universitario de Albacete. Finalmente forman parte de nuestro estudio 166 mujeres. Se estudia la función sexual con el Cuestionario de Función Sexual de la Mujer (FSM ®). RESULTADOS: Encontramos que, tras la histerectomía, la función sexual de la mujer mejora en algunos aspectos y no cambia en otros. Las menores de 55 años presentan mejoría en el Deseo, en la Excitación y en la Frecuencia de la actividad sexual, y disminución de Problemas con la penetración vaginal; todo esto es ya manifiesto a los 3 meses de la intervención, sin cambios posteriores. La Ansiedad anticipatoria también mejora entre el tercer y noveno mes. Observamos tendencia a la mejoría en el dominio de Capacidad para disfrutar de su vida sexual en general. En mayores de 55 años solo encontramos aumento en la Frecuencia de actividad sexual a los 9 meses de la cirugía. CONCLUSIONES: Tras la histerectomía, la función sexual de la mujer mejora o no cambia. La mejoría se encuentra principalmente en menores de 55 años


OBJECTIVE: Women may experience anxiety because of the possible effects of hysterectomy on sexual function, but studies have shown conflicting results on this topic. Given the frequency of this procedure, the aim of this study is to determine whether sexual function changes after hysterectomy. MATERIAL AND METHODS: A comparison was made of sexual function before hysterectomy to sexual function at 3 and 9 months after the procedure in 299 women who underwent hysterectomy between 1 November 2012 and 30 November 2014, at the Hospital and University Complex of Albacete, Spain. A total of 166 women were finally included in the study. Sexual function was studied using the Women's Sexual Function Questionnaire (Cuestionario de Función Sexual de la Mujer, FSM ®). RESULTS: It was found that some aspects of female sexual function improved after hysterectomy, whereas others did not change. Those younger than 55 years old experience improvements in sexual desire, excitement, and frequency of sexual activity, and had a decrease in problems with vaginal penetration. These changes were all evident 3 months post-intervention, and no changes occurred thereafter. Anticipatory anxiety also improved between the third and ninth month. An upward trend was observed in the general enjoyment of sex life. In those older than 55 years, an increase was only found in the frequency of sexual activity at 9 months post-operation. CONCLUSIONS: After hysterectomy, female sexual function either improves or remains unchanged. Improvement is primarily found in women younger than 55 years old


Assuntos
Humanos , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Histerectomia/métodos , Histerectomia/psicologia , Sexualidade/psicologia , Comportamento Sexual/psicologia , Comportamento Sexual/fisiologia , Inquéritos e Questionários , Estudos Prospectivos , Estudos Longitudinais
12.
Arch Sex Behav ; 49(7): 2421-2429, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32356085

RESUMO

Mostly heterosexual men describe themselves as slightly bisexual, with predominant sexual attraction to women but occasional attraction to men. After "completely heterosexual," "mostly heterosexual" is the most common male sexual orientation, by self-report. However, self-reported bisexual feelings among men can diverge from patterns of genital arousal, an objective measure of sexual interest with high validity. We compared 49 mostly heterosexual and 50 completely heterosexual men's patterns of genital and subjective sexual arousal to male and female erotic stimuli. In addition, we compared these groups on relevant self-report measures pertaining to sexual feelings, identity, and behavior. Results supported increased bisexual arousal with respect to self-report and genital arousal pattern among the mostly heterosexual men, compared with the completely heterosexual men. Furthermore, mostly heterosexual men reported more childhood gender nonconformity, greater male sex partners, and less self-reported disgust or aversion to sex acts with men. "Mostly heterosexual" appears to be a gradation of male sexual orientation associated with unique genital arousal patterns, among other correlates.


Assuntos
Nível de Alerta/fisiologia , Bissexualidade/psicologia , Heterossexualidade/fisiologia , Comportamento Sexual/fisiologia , Afeto , Humanos , Masculino , Autorrelato
13.
Arch Sex Behav ; 49(7): 2469-2479, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32356086

RESUMO

Gender nonconformity (femininity in males, masculinity in females) is more common in non-heterosexual (bisexual and homosexual) than heterosexual individuals. In the past research (Watts, Holmes, Raines, Orbell, & Rieger, 2018b), identical twins discordant for sexual orientation were perceived more similar in their gender nonconformity than unrelated heterosexual and non-heterosexual people. Yet, these perceptions were based on photographs, which do not contain all aspects of gender nonconformity, such as movement and sound. This could have led to an underestimation of observable difference within twin pairs. We examined evaluations of video recordings from adult identical twins with discordant sexual orientations (eight male pairs, 11 female pairs). These twins were a small subset of those who participated in Watts et al. (2018b). Non-heterosexual twins were rated as significantly more gender nonconforming than their heterosexual co-twins, but only when males and females were combined. Their difference was smaller than the analogous difference between identical twins who were concordant heterosexual (three male pairs, three female pairs) and, unrelated to them, identical twins who were concordant non-heterosexual (six male pairs, two female pairs). These patterns were partially confirmed with twins' self-reported gender nonconformity. Shared influences possibly made twins from discordant pairs somewhat similar in their gender nonconformity, even if non-shared factors differentiated their sexual orientations.


Assuntos
Comportamento Sexual/fisiologia , Adulto , Feminino , Humanos , Masculino , Gêmeos Monozigóticos , Gravação em Vídeo
14.
J Womens Health (Larchmt) ; 29(7): 1017-1020, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32397852

RESUMO

Background: The impact of nipple sensation and its relationship to sexual function have often been neglected in medical literature. However, several recent studies report the importance of the nipple/areola complex (NAC) in sexual arousal and overall function. The nipple is composed of smooth muscle that can be erected via adrenergic nerves. In two complementary studies, we demonstrate that stimulation of the alpha-1 adrenergic receptor in the NAC with topical adrenergic agents can initiate erection of the nipple, increase NAC sensitivity, and improve sexual function. Materials and Methods: Thirteen breast surgery patients with nipple sensitivity loss were recruited to an unblinded study of topical phenylephrine hydrochloride. Sensitivity to pressure was measured before and after the application of the intervention to the NAC. In a second pilot study, 35 women completed a double-blinded placebo-controlled trial of a novel formulation, RJ101, containing a norepinephrine releasing agent. The intervention or placebo was applied to the NAC 30 minutes before sexual activity over the 4-week trial period. The arousal, lubrication, and orgasm domains of the female sexual function index (FSFI) were used to measure sexual function. Results: The application of phenylephrine hydrochloride was shown to increase nipple sensitivity to pressure by an average of 20% in our cohort of 13 breast augmentation patients. In addition, it was shown that intermittent application of the alpha-1 agonist for 8 weeks increased basal NAC sensitivity. In the follow-up pilot study, we demonstrate that stimulation of the NAC with RJ101 produced statistically significant increases versus placebo in the lubrication and orgasm domains of the FSFI, p = 0.0226 and p = 0.0269, respectively. Conclusion: For the first time, we demonstrate that the application of a topical alpha-1 adrenergic receptor agonist or a norepinephrine-releasing agent increases the sensitivity of the NAC and subsequently significantly improves sexual function.


Assuntos
Antagonistas de Receptores Adrenérgicos alfa 1/administração & dosagem , Mastectomia/efeitos adversos , Mamilos/efeitos dos fármacos , Orgasmo/efeitos dos fármacos , Transtornos das Sensações/etiologia , Comportamento Sexual/fisiologia , Disfunções Sexuais Fisiológicas/terapia , Administração Tópica , Antagonistas de Receptores Adrenérgicos alfa 1/uso terapêutico , Adulto , Feminino , Humanos , Mamoplastia/efeitos adversos , Mamilos/fisiologia , Satisfação do Paciente , Pressão , Transtornos das Sensações/fisiopatologia , Disfunções Sexuais Fisiológicas/fisiopatologia , Adulto Jovem
15.
BMC Infect Dis ; 20(1): 299, 2020 Apr 22.
Artigo em Inglês | MEDLINE | ID: mdl-32321442

RESUMO

BACKGROUND: Sexualized drug use (SDU) refers to use of any psychoactive substance before/during sexual intercourse. Chemsex is a subset of SDU, which is defined as the use of some specific psychoactive substances (methamphetamine, mephedrone, γ-hydroxybutyrate, ketamine and cocaine) before/during sexual intercourse. SDU and chemsex are prevalent among gay, bisexual and other men who have sex with men (GBMSM). This study investigated uptake and willingness to use pre-exposure prophylaxis (PrEP) among a sample of GBMSM in Hong Kong with experience of SDU in the past year. METHODS: A total of 600 GBMSM were recruited by convenient sampling through outreaching in gay venues, online recruitment and peer referral. Participants completed a cross-sectional anonymous telephone interview. This study was based on a subsample of 580 GBMSM self-reported as HIV negative/unknown sero-status. RESULTS: Of the participants, 82 (14.1%) and 37 (6.4%) had experience of SDU and chemsex in the past year. The prevalence of PrEP uptake was 4.0% among all participants and 14.6% among those with experience of SDU in the past year. Among GBMSM with experience of SDU in the past year who were not on PrEP (n = 70), 67.1% were willing to use daily oral PrEP in the next 6 months. Multivariate logistic regression models showed that positive attitudes toward PrEP (AOR: 2.37, 95%CI: 1.47, 3.82), perceived support from significant others to use PrEP (AOR: 9.67, 95%CI: 2.95, 31.71), and perceived behavioral control of using PrEP (AOR: 19.68, 95%CI: 5.44, 71.26) were significantly associated with higher willingness to use PrEP. CONCLUSION: GBMSM with experience of recent SDU are potentially good candidates of PrEP implementation. This group of GBMSM reported high prevalence of uptake and willingness to use PrEP. Perceptions related to PrEP based on the Theory of Planned Behavior were significantly associated with willingness to use PrEP.


Assuntos
Homossexualidade Masculina/estatística & dados numéricos , Participação do Paciente/estatística & dados numéricos , Profilaxia Pré-Exposição/métodos , Psicotrópicos/uso terapêutico , Minorias Sexuais e de Gênero/estatística & dados numéricos , Doenças Sexualmente Transmissíveis/prevenção & controle , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Volição , Adolescente , Adulto , Atitude Frente a Saúde , Bissexualidade/psicologia , Bissexualidade/estatística & dados numéricos , China/epidemiologia , Estudos Transversais , Infecções por HIV/epidemiologia , Infecções por HIV/prevenção & controle , Conhecimentos, Atitudes e Prática em Saúde , Homossexualidade Masculina/psicologia , Hong Kong/epidemiologia , Humanos , Entrevistas como Assunto , Masculino , Pessoa de Meia-Idade , Profilaxia Pré-Exposição/estatística & dados numéricos , Prevalência , Comportamento Sexual/fisiologia , Comportamento Sexual/estatística & dados numéricos , Minorias Sexuais e de Gênero/psicologia , Doenças Sexualmente Transmissíveis/epidemiologia , Inquéritos e Questionários , Volição/fisiologia , Adulto Jovem
16.
PLoS One ; 15(3): e0230838, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32231386

RESUMO

A growing body of evidence suggests that men may perceive women's bodily odour to be more attractive during the high-fertility ovulatory phase than during other phases in the menstrual cycle. In particular, women's bodily odour may influence important aspects of male mating behaviour, but the precise nature of this phenomena remains to be elucidated. Twenty-six men and five women participated in the study. Each woman wore a cotton T-shirt during the night for 3 days during the ovulatory phase, after which the regions of the T-shirt that had been in contact with the woman's chest, armpits, and back, were cut out of the garment. We evaluated the changes in testosterone and cortisol levels in the saliva of men who smelled these cloth pieces. The odour emitted from the backs of women in the ovulatory phase was found to increase testosterone secretion in men, whereas the odour emitted from the chests of women in the ovulatory phase reduced cortisol secretion in men. These results suggest that the odour of specific body parts of women modulate unconscious physiological reactions in men.


Assuntos
Hidrocortisona/metabolismo , Odorantes , Ovulação/metabolismo , Testosterona/metabolismo , Feminino , Humanos , Masculino , Ciclo Menstrual/metabolismo , Comportamento Sexual/efeitos dos fármacos , Comportamento Sexual/fisiologia , Adulto Jovem
17.
Pediatrics ; 145(5)2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-32341182

RESUMO

Pediatricians are encouraged to address male adolescent sexual and reproductive health on a regular basis, including taking a sexual history, discussing healthy sexuality, performing an appropriate physical examination, providing patient-centered and age-appropriate anticipatory guidance, and administering appropriate vaccinations. These services can be provided to male adolescent patients in a confidential and culturally appropriate manner, can promote healthy sexual relationships and responsibility, can and involve parents in age-appropriate discussions about sexual health.


Assuntos
Comportamento do Adolescente/psicologia , Saúde Reprodutiva/tendências , Comportamento Sexual/psicologia , Saúde Sexual/tendências , Adolescente , Comportamento do Adolescente/fisiologia , Aconselhamento/métodos , Aconselhamento/tendências , Humanos , Masculino , Comportamento Sexual/fisiologia
18.
Rev. int. med. cienc. act. fis. deporte ; 20(77): 133-153, mar. 2020. tab
Artigo em Espanhol | IBECS | ID: ibc-194773

RESUMO

El deseo sexual es un estado de motivación que puede inducir a la actividad sexual. La actividad física está relacionada con el bienestar en social y sexual. El objetivo del presente estudio fue analizar el deseo sexual en relación con la actividad física y su impacto en la excitación e inhibición sexual en una población de jóvenes adultos. La muestra estuvo conformada por 485 participantes (327 mujeres y 158 hombres), entre 18 y 35 años. Este estudio requirió el cumplimiento de un cuestionario sociodemográfico, Inventario de Deseo Sexual (diádico y solitario), Cuestionario de Actividad Física (IPAQ) y Escalas de Inhibición y Excitación Sexual (SES-SIS). Los principales resultados mostraron relación entre el deseo y la actividad física con la excitación y la inhibición sexual, concluyendo que niveles de actividad medios y altos contribuyen de forma positiva en la sexualidad. Futuras investigaciones podrían proponer el ejercicio como intervención en problemas de deseo


Sexual desire is a state of motivation that can induce to participate in sexual activity. Physical activity is related to the well-being in both social and sexual relationships. The aim of this study was to analyze sexual desire in relation to physical activity and its impact on sexual excitation and inhibition in a population of young adults. The total sample consisted of 485 participants (327 women and 158 men), aged between 18 and 35 years. This study required the fulfillment of a sociodemographic questionnaire, the Sexual Desire Inventory (dyadic and solitary), the Physical Activity Questionnaire (IPAQ) and the Sexual Inhibition and Sexual Excitation Scales (SES-SIS). The main results showed that there is a relationship between desire and physical activity with excitement and sexual inhibition, concluding that medium and high activity levels contribute positively in people's sexual behavior. Future research could propose exercise as an intervention in problems of desire


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Adulto , Sexualidade/psicologia , Atividade Motora/fisiologia , Esportes/psicologia , Comportamento Sexual/psicologia , Sexualidade/fisiologia , Comportamento Sexual/fisiologia , Imagem Corporal/psicologia , Inquéritos e Questionários
19.
Mult Scler Relat Disord ; 37: 101440, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-32173004

RESUMO

OBJECTIVE: We aimed to determine the association between gender identity and sexual orientation on health care utilization in persons with multiple sclerosis (MS), as well as satisfaction with their doctor and comfort discussing sexual health with their doctor. METHODS: We surveyed participants from the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry regarding their gender identity and sexual orientation in 2017. Participants also reported their sociodemographic characteristics, disability status, health behaviors and health care utilization, including whether any hospitalizations or emergency room (ER) visits occurred or any disease-modifying therapy (DMT) was used within the last six months. We compared the likelihood of hospitalizations, ER visits and DMT use between (i) cisgender and transgender participants; and (ii) heterosexual, homosexual, and "other sexual orientation" participants using multivariable logistic regression models adjusting for potential confounding factors. RESULTS: Of the 5,604 eligible responders, 1168 (20.8%) reported their sex at birth as male and 4436 reported their sex at birth as female (79.2%). Twenty-five (0.45%) participants identified as transgender and 260 (4.6%) as non-heterosexual individuals. As compared to participants who reported their sexual orientation as heterosexual, non-heterosexual participants were younger, with an earlier age at MS symptom onset, more likely to have a post-secondary education, and more likely to be single. The frequency of any ER visits, any hospital admissions, and DMT use did not differ according to gender identity did not differ according to gender identity or sexual orientation. As compared to cisgender participants, transgender participants reported less comfort (p < 0.042) discussing sexual health with their doctor; findings were similar for non-heterosexual participants as compared to heterosexual participants. Participants reporting other sexual orientation also reported lower satisfaction (p < 0.039) with their doctor than other participants. CONCLUSION: Gender identity and sexual orientation were not associated with differences in healthcare utilization in persons with MS. However, health care experiences and satisfaction with care may be altered by gender identity and sexual orientation.


Assuntos
Identidade de Gênero , Esclerose Múltipla/genética , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Comportamento Sexual/fisiologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação Pessoal , Pessoas Transgênero/psicologia
20.
Dig Dis Sci ; 65(3): 800-817, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-32030625

RESUMO

Recent studies have raised interest in the possibility that dysbiosis of the gut microbiome (i.e., the communities of bacteria residing in the intestine) in HIV-infected patients could contribute to chronic immune activation, and, thus, to elevated mortality and increased risk of inflammation-related clinical diseases (e.g., stroke, cardiovascular disease, cancer, long-bone fractures, and renal dysfunction) found even in those on effective antiretroviral therapy. Yet, to date, a consistent pattern of HIV-associated dysbiosis has not been identified. What is becoming clear, however, is that status as a man who has sex with men (MSM) may profoundly impact the structure of the gut microbiota, and that this factor likely confounded many HIV-related intestinal microbiome studies. However, what factor associated with MSM status drives these gut microbiota-related changes is unclear, and what impact, if any, these changes may have on the health of MSM is unknown. In this review, we outline available data on changes in the structure of the gut microbiome in HIV, based on studies that controlled for MSM status. We then examine what is known regarding the gut microbiota in MSM, and consider possible implications for research and the health of this population. Lastly, we discuss knowledge gaps and needed future studies.


Assuntos
Disbiose/microbiologia , Microbioma Gastrointestinal/fisiologia , Infecções por HIV/microbiologia , Homossexualidade Masculina , Comportamento Sexual/fisiologia , Disbiose/epidemiologia , Feminino , Infecções por HIV/epidemiologia , Humanos , Masculino
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