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1.
Zhonghua Yan Ke Za Zhi ; 56(12): 914-919, 2020 Dec 11.
Artigo em Chinês | MEDLINE | ID: mdl-33342117

RESUMO

Objective: To summarize the clinical and fundus imaging features of purified protein derivative and T-spot positive tubercular serpiginous-like choroiditis (PTP-SLC) patients. Methods: This retrospective study consecutively enrolled 13 PTP-SLC patients (21 eyes) in Beijing Tongren Hospital from November 2015 to November 2017. There were 8 males and 5 females with an average age of (45.2±12.1) years. Medical history and results of systemic and ophthalmological examinations, such us fundus autofluorescence photography, optical coherence tomography (OCT), fluorescein fundus angiography (FFA) and indocyanine green angiography, were evaluated. Results: Eight patients had binocular disease with an average interval time of (8.4±7.9) years. The average visual acuity of all patients was 0.3, and 4 patients had a clear history of exposure to tuberculosis. The active lesions in the PTP-SLC patients were homogeneous and creamish-yellow with unclear boundaries. Fundus autofluorescence showed an ill-defined, diffuse hyperautofluorescent zone. OCT showed punctate hyperreflexes between the choroidal stroma, destruction of the outer retinal structure with intraretinal edema and discrete vitreal hyper-reflective spots. FFA showed hypofluorescence in the active lesion at early stage and diffuse hyperfluorescence with leakage. Indocyanine green angiography showed persistent hypofluorescence. Conclusions: PTP-SLC fundus lesions are mainly manifested as homogeneous creamish-yellow lesions with unclear boundaries and high in autofluorescence. The involvement of the choroid and the outer layer of the retina can be observed on OCT. FFA can find more retinal vascular inflammatory changes. It is difficult to distinguish PTP-SLC from serpiginous choroiditis simply based on clinical and epidemiological characteristics. The pathogenic examination of tuberculosis is still the key to differential diagnosis (Chin J Ophthalmol, 2020, 56: 914-919).


Assuntos
Corioidite , Síndromes do Ponto Branco , Adulto , Corioidite/diagnóstico por imagem , Feminino , Angiofluoresceinografia , Fundo de Olho , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Tomografia de Coerência Óptica
4.
Am J Ophthalmol ; 218: 279-287, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32621891

RESUMO

PURPOSE: This study evaluated the risk and risk factors for exudative retinal detachment (ERD) in ocular inflammatory diseases. DESIGN: Retrospective cohort study. METHODS: Patients with noninfectious ocular inflammation had been followed longitudinally between 1978 and 2007 at 4 US subspecialty uveitis centers. The main outcome measurements were occurrences of ERD and predictive factors. RESULTS: A total of 176 of 14,612 eyes with ocular inflammation presented with ERD. Among uveitis cases, Vogt-Koyanagi-Harada syndrome (VKH) (odds ratio [OR] = 109), undifferentiated choroiditis (OR = 9.18), sympathetic ophthalmia (OR = 8.43), primary or secondary panuveitis (OR = 7.09), multifocal choroiditis with panuveitis (OR = 4.51), and "other" forms of posterior uveitis (OR = 16.9) were associated with a higher prevalence of ERD. Among the 9,209 uveitic or scleritic eyes initially free of ERD and followed, 137 incident ERD cases were observed over 28,949 eye-years at risk (incidence rate = 0.47% [0.40%-0.56%/eye-year]). VKH (HR = 13.2), sympathetic ophthalmia (HR = 5.82), undifferentiated choroiditis (HR = 6.03), primary or secondary panuveitis (HR = 4.21), and rheumatoid arthritis (HR = 3.30) were significantly associated with incident ERD. A significant dose-response relationship with the prevalence and incidence of ERD were observed for AC cells and vitreous cell activity. African Americans had significantly higher prevalence and incidence of ERD. CONCLUSIONS: Other ocular inflammatory conditions in addition to VKH syndrome and posterior scleritis were associated with increased risk of ERD, indicating that ERD does not necessarily dictate a diagnosis of VKH or posterior scleritis. In addition, the relationship between ERD and inflammatory severity factors implies that inflammation is a key predictive factor associated with developing ERD and requires early and vigorous control.


Assuntos
Corioidite/epidemiologia , Oftalmia Simpática/epidemiologia , Descolamento Retiniano/epidemiologia , Uveíte Posterior/epidemiologia , Síndrome Uveomeningoencefálica/epidemiologia , Adulto , Exsudatos e Transudatos , Feminino , Angiofluoresceinografia , Humanos , Incidência , Inflamação/epidemiologia , Masculino , Pessoa de Meia-Idade , Prevalência , Descolamento Retiniano/diagnóstico , Estudos Retrospectivos , Medição de Risco , Fatores de Risco , Acuidade Visual/fisiologia
5.
J Fr Ophtalmol ; 43(3): 243-255, 2020 Mar.
Artigo em Francês | MEDLINE | ID: mdl-32007311

RESUMO

Placoid pigment epitheliopathy and serpiginous choroiditis are among the white dot retinal syndromes and possess similarities that can cause confusion between these two diseases. However, they are very different in terms of their progression and prognosis, which requires a diagnosis of certainty in order to better manage the patients with the diseases and identify potentially serious progressive complications. The clinical presentation, results of testing, differential diagnoses and treatment of these two pathologies are discussed in this article.


Assuntos
Epitélio Pigmentado Ocular/patologia , Doenças Retinianas , Síndromes do Ponto Branco , Corioidite/diagnóstico , Corioidite/patologia , Corioidite/terapia , Diagnóstico Diferencial , Progressão da Doença , Humanos , Transtornos da Pigmentação/diagnóstico , Transtornos da Pigmentação/patologia , Transtornos da Pigmentação/terapia , Prognóstico , Doenças Retinianas/diagnóstico , Doenças Retinianas/patologia , Doenças Retinianas/terapia , Síndromes do Ponto Branco/diagnóstico , Síndromes do Ponto Branco/terapia
6.
Rev Iberoam Micol ; 36(3): 155-159, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31676212

RESUMO

BACKGROUND: Ocular involvement in AIDS patients is a common event mainly caused by inflammation or infection. Despite the high prevalence rate of cryptococcosis in these individuals, ocular features have been occasionally described. CASE REPORT: A 20-year-old Brazilian female with HIV infection recently diagnosed was admitted with a respiratory profile presumptively diagnosed as Pneumocystis jirovecii pneumonia; an ophthalmologic exam suggested choroiditis by this agent as well. She was complaining of headaches and blurred vision which led to cryptococcal meningitis diagnosis by a CSF positive India ink stain and Cryptococcus neoformans positive culture. Despite therapy based on amphotericin B plus fluconazole, her clinical state progressively worsened and the patient died one week later. At necropsy, disseminated cryptococcal infection was evidenced in several organs including eyes, which presented bilateral chorioretinitis. CONCLUSIONS: Cryptococcal ocular involvement in AIDS patients has been occasionally proved among the cases already reported. Thus, the post mortem exam is still pivotal to improve the quality of the clinical diagnosis, especially in limited-resource settings.


Assuntos
Infecções Oportunistas Relacionadas com a AIDS/complicações , Corioidite/microbiologia , Criptococose/complicações , Cryptococcus neoformans , Evolução Fatal , Feminino , Humanos , Adulto Jovem
7.
Medicine (Baltimore) ; 98(47): e18152, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31764858

RESUMO

RATIONALE: Proliferation of retinal pigment epithelium (RPE) is typically observed in limited ocular disorders, in connection with the local mechanism of RPE proliferation-mediated wound repair. Bilateral and diffuse type RPE proliferation is considered to be associated with paraneoplastic syndromes, such as a bilateral diffuse uveal melanocytic proliferation. However, other reported diseases that induce bilateral diffuse RPE proliferation are quite rare, especially for patients who are considered to have a non-malignant status. PATIENT CONCERNS: The bilateral eyes of a 47-year-old woman with bilateral ocular inflammation, presented united multiple small to medium white retinal lesions during the disease progress. DIAGNOSES: Optical coherence tomography showed scattered serous retinal detachments, choroidal folds, choroidal thickening and diffuse RPE proliferation. As autofluorescence and angiography showed a "giraffe pattern", bilateral diffuse uveal melanocytic proliferation was suspected. However, systemic investigations identified no malignancy. In consideration of the above findings, choroidal inflammation was thought to be the major cause of this condition. INTERVENTIONS: The patient was administered intensive systemic steroids. Over the next 2 months, the amount of steroid was tapered off. OUTCOMES: After administration, the bilateral diffuse RPE proliferation settled down. During the 2-year follow-up, there was no recurrence of ocular inflammation and diffuse RPE proliferation, or any other malignancy found. LESSONS: This finding demonstrates that bilateral diffuse RPE proliferation can be generated as a secondary phenomenon of choroidal inflammation in patients with a non-malignant status.


Assuntos
Corioidite/complicações , Doenças Retinianas/etiologia , Doenças Retinianas/patologia , Epitélio Pigmentado da Retina/patologia , Proliferação de Células , Feminino , Humanos , Pessoa de Meia-Idade
8.
Ophthalmologe ; 116(12): 1235-1256, 2019 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-31748943

RESUMO

The white dot syndromes include a group of diseases which are characterized by multiple yellowish-white foci in the outer retina, retinal pigment epithelium, and choroid. For clinicians and researchers alike they present significant diagnostic and therapeutic challenges. White dot syndromes include primary inflammatory choriocapillaropathies, such as acute posterior multifocal placoid pigment epitheliopathy (APMPPE)/acute multifocal ischemic choriocapillaropathy (AMIC), multiple evanescent white dot syndrome (MEWDS)/acute idiopathic blind spot enlargement (AIBSE), multifocal choroiditis (MFC), punctate inner choroidopathy (PIC), serpiginous choroiditis (SC), acute zonal occult outer retinopathy (AZOOR), and acute macular neuroretinopathy (AMN). Among the primary stromal choroiditis is birdshot retinochoroidopathy (BSRC); however, the pathogenesis of these disorders is largely unknown. Immunological reactions to previous viral infections with a genetic disposition seem to be a common denominator.


Assuntos
Doenças da Coroide , Corioidite , Doenças Retinianas , Síndromes do Ponto Branco , Doença Aguda , Doenças da Coroide/diagnóstico , Doenças da Coroide/terapia , Corioidite/diagnóstico , Corioidite/terapia , Angiofluoresceinografia , Humanos , Doenças Retinianas/diagnóstico , Doenças Retinianas/terapia , Síndromes do Ponto Branco/diagnóstico , Síndromes do Ponto Branco/terapia
9.
Rev. iberoam. micol ; 36(3): 155-159, jul.-sept. 2019. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-191406

RESUMO

Background: Ocular involvement in AIDS patients is a common event mainly caused by inflammation or infection. Despite the high prevalence rate of cryptococcosis in these individuals, ocular features have been occasionally described. Case report: A 20-year-old Brazilian female with HIV infection recently diagnosed was admitted with a respiratory profile presumptively diagnosed as Pneumocystis jirovecii pneumonia; an ophthalmologic exam suggested choroiditis by this agent as well. She was complaining of headaches and blurred vision which led to cryptococcal meningitis diagnosis by a CSF positive India ink stain and Cryptococcus neoformans positive culture. Despite therapy based on amphotericin B plus fluconazole, her clinical state progressively worsened and the patient died one week later. At necropsy, disseminated cryptococcal infection was evidenced in several organs including eyes, which presented bilateral chorioretinitis. Conclusions: Cryptococcal ocular involvement in AIDS patients has been occasionally proved among the cases already reported. Thus, the post mortem exam is still pivotal to improve the quality of the clinical diagnosis, especially in limited-resource settingsl


Antecedentes: La afectación ocular en pacientes con sida es una circunstancia común provocada principalmente por procesos inflamatorios o infecciosos. A pesar de la alta prevalencia de criptococosis en estos individuos, los hallazgos oculares solo se describen ocasionalmente. Caso clínico: Una mujer brasileña de 20 años, diagnosticada poco tiempo antes de infección por el VIH, fue hospitalizada por dificultad respiratoria con el presunto diagnóstico de neumonía por Pneumocystis jirovecii; el examen oftalmológico sugirió también la existencia de coroiditis por el mismo agente etiológico. Las quejas de la paciente por cefalea y visión borrosa orientaron el diagnóstico hacia la criptococosis meníngea, confirmada por el examen directo y el crecimiento de Cryptococcus neoformans en el cultivo del líquido cefalorraquídeo. A pesar de haber comenzado un tratamiento con anfotericina B y fluconazol, el estado clínico empeoró progresivamente y la paciente falleció una semana después. La necropsia mostró criptococosis diseminada en varios órganos, incluidos los ojos, que presentaban coriorretinitis bilateral. Conclusiones: La criptococosis ocular en pacientes con VIH se ha descrito ocasionalmente en los casos publicados. Por este motivo, la necropsia todavía es fundamental para mejorar la calidad del diagnóstico clínico de esa enfermedad, especialmente en regiones con recursos limitados


Assuntos
Humanos , Feminino , Adulto Jovem , Infecções por HIV/complicações , Corioidite/microbiologia , Fungemia/diagnóstico , Criptococose/complicações , Cryptococcus neoformans/isolamento & purificação , Pneumonia/microbiologia , Meningite Criptocócica/complicações , Coriorretinite/microbiologia , Infecções Oportunistas Relacionadas com a AIDS/diagnóstico , Cryptococcus neoformans/patogenicidade , Diagnóstico Diferencial , Endoftalmite/microbiologia , Técnicas de Genotipagem/métodos , Evolução Fatal
10.
Indian J Ophthalmol ; 67(8): 1362-1365, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31332144

RESUMO

A 47-year-old female presented with optic disc oedema, peripapillary subretinal fluid and scattered areas of choroiditis. Her ultrasound B-scan showed sclerochoroidal thickening with widening of sub-Tenon space. Subsequent investigations revealed a positive Mantoux test and high-resolution computed tomography of the chest was suggestive of pulmonary involvement. She responded well to antitubercular treatment and systemic corticosteroid. A review of the literature was conducted to identify additional reports on similar cases and discussed. A high index of suspicion and appropriate laboratory work-up can aid in the diagnosis of tuberculous posterior scleritis.


Assuntos
Infecções Oculares Bacterianas/diagnóstico , Esclerite/diagnóstico , Tuberculose Ocular/diagnóstico , Antituberculosos/uso terapêutico , Corioidite/diagnóstico , Corioidite/tratamento farmacológico , Corioidite/microbiologia , Corantes/administração & dosagem , Infecções Oculares Bacterianas/tratamento farmacológico , Infecções Oculares Bacterianas/microbiologia , Feminino , Angiofluoresceinografia , Glucocorticoides/uso terapêutico , Humanos , Verde de Indocianina/administração & dosagem , Pessoa de Meia-Idade , Papiledema/diagnóstico , Papiledema/tratamento farmacológico , Papiledema/microbiologia , Esclerite/tratamento farmacológico , Esclerite/microbiologia , Líquido Sub-Retiniano , Tuberculose Ocular/tratamento farmacológico , Tuberculose Ocular/microbiologia , Tuberculose Pulmonar/diagnóstico , Tuberculose Pulmonar/tratamento farmacológico , Acuidade Visual
11.
Optom Vis Sci ; 96(8): 620-624, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31318798

RESUMO

SIGNIFICANCE: Serpiginous choroiditis is a rare yet visually debilitating condition. To date, there is no established consensus on treatment protocol. This article presents a case report of macular serpiginous choroiditis and reviews supporting data for immunosuppressive treatment plans. PURPOSE: The purpose of this study was to examine a case of atypical serpiginous choroiditis with emphasis on diagnostic testing and treatment options. CASE REPORT: A 62-year-old man presented with new, bilateral, yellow chorioretinal placoid lesions within the posterior pole. Optical coherence tomography revealed focal hyperreflective retinal pigment epithelium lesions with disruption of outer retinal layers. Fundus fluorescein angiography demonstrated stable hyperfluorescent lesions with the absence of fluid leakage. Further testing ruled out possible systemic correlation. CONCLUSIONS: Macular serpiginous choroiditis is infrequently encountered; however, various differentials must be considered before making the diagnosis. Optical coherence tomography and fundus fluorescein angiography serve as useful tools in aiding the diagnosis. Treatment of serpiginous choroiditis must be initiated with caution given the high risk of adverse effects.


Assuntos
Corioidite/diagnóstico , Corioide/irrigação sanguínea , Corioide/patologia , Angiofluoresceinografia/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Tomografia de Coerência Óptica
12.
Indian J Ophthalmol ; 67(7): 1210-1212, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-31238469

RESUMO

Tuberculous optic neuropathy that includes papillitis, neuroretinitis, and optic nerve tubercle is a rare presentation of ocular tuberculosis. Though contagious spread from choroid following the hematogenous dissemination of the bacilli has been implicated in the optic nerve involvement, unlike neuroretinitis, optic nerve and choroidal involvement are usually considered as two separate clinical entities. We report a case of optic nerve involvement in a 33-year-old male who had concurrent choroidal involvement at present and also in the past. A strong history of contact with patients of pulmonary tuberculosis, positive tuberculin skin test, interferon gamma release assay, and high-resolution computed tomography helped us to clinch the diagnosis. Patients responded to systemic corticosteroid therapy and anti-tuberculosis treatment. Choroidal involvement in a case of inflammatory optic neuropathy should arise suspicion of tuberculous etiology.


Assuntos
Corioidite/complicações , Infecções Oculares Bacterianas/complicações , Disco Óptico/patologia , Doenças do Nervo Óptico/etiologia , Tuberculose Ocular/complicações , Adulto , Corioidite/diagnóstico , Infecções Oculares Bacterianas/diagnóstico , Angiofluoresceinografia , Fundo de Olho , Humanos , Masculino , Doenças do Nervo Óptico/diagnóstico , Tuberculose Ocular/diagnóstico , Acuidade Visual
14.
Vestn Oftalmol ; 135(2): 108-112, 2019.
Artigo em Russo | MEDLINE | ID: mdl-31215541

RESUMO

The article describes a difficult case of differential diagnosis of local choroiditis developed after influenza (flu) vaccination in a patient with bronchial asthma who receives systemic steroid therapy.


Assuntos
Corioidite , Influenza Humana , Angiofluoresceinografia , Humanos , Vacinação , Acuidade Visual
15.
BMC Ophthalmol ; 19(1): 95, 2019 Apr 24.
Artigo em Inglês | MEDLINE | ID: mdl-31014297

RESUMO

BACKGROUND: The optimal treatment of serpiginous choroiditis is not established. While recent reports indicate the efficacy of adalimumab, there is limited evidence. We present a case of serpiginous choroiditis refractory to steroids, immunosuppressants, and adalimumab. CASE PRESENTATION: An 18-year-old woman presented with severe vision loss in both eyes. A fundus examination revealed a foveal grayish-white lesion, and optical coherence tomography revealed outer retinal damage. She was diagnosed with serpiginous choroiditis and treated with steroid pulse therapy, but the disease progressed continuously. The addition of sub-Tenon's injection of triamcinolone and oral cyclosporine did not change the disease course. We also administered subcutaneous injections of adalimumab, but even with the intensive treatment, the retinal lesions and subsequent atrophy progressed. Her right and left visual acuity declined from 20/22 to 20/66 and 20/200, respectively, during the 9 months of follow-up. CONCLUSION: Here, we report a case of serpiginous choroiditis refractory to corticosteroids, immunosuppressants, and adalimumab. Further studies are needed to establish the optimal treatment for such cases.


Assuntos
Adalimumab/uso terapêutico , Anti-Inflamatórios/uso terapêutico , Corioidite/tratamento farmacológico , Doença Aguda , Adolescente , Feminino , Humanos , Imunossupressores/uso terapêutico , Esteroides/uso terapêutico , Falha de Tratamento
16.
Klin Monbl Augenheilkd ; 236(4): 492-510, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30891715

RESUMO

The purpose of this work was to give a comprehensive and updated review on two primary stromal choroiditis entities, Vogt-Koyanagi-Harada disease (VKH) and birdshot retinochoroiditis (BRC). Their appraisal has become much more precise thanks to new investigational methods, such as indocyanine green angiography (ICGA) and enhanced depth imaging optical coherence tomography (EDI-OCT), which give substantially improved imaging access to the choroid. In this review, we focus on the crucial changes brought by this progress in the understanding, diagnosis, and management of these disorders. Application of these methods makes it possible to reach an early diagnosis, therefore allowing early treatment, which has led to a profound improvement in outcomes when compared to previous management.


Assuntos
Corioidite , Síndrome Uveomeningoencefálica , Corioide , Corioidite/diagnóstico , Angiofluoresceinografia , Humanos , Tomografia de Coerência Óptica , Síndrome Uveomeningoencefálica/diagnóstico
17.
J Fr Ophtalmol ; 42(3): 303-321, 2019 Mar.
Artigo em Francês | MEDLINE | ID: mdl-30850198

RESUMO

Sarcoidosis is a systemic granulomatosis characterized by the formation of epithelioid and giant cell granulomas without caseous necrosis. To make the diagnosis, it is necessary to prove systemic granulomatosis involving at least two organs; but in practice, a combination of clinical, paraclinical and histologic findings is used. It affects predominantly women with a bimodal age distribution: 25-29years and 65-69years. The most commonly affected organs are the mediastinal lymphatic system, lungs, skin and eyes. Ophthalmological involvement is present in 20 to 50% of cases. The typical ocular presentation is that of granulomatous uveitis associated with venous retinal vasculitis and lesions of peripheral multifocal choroiditis. This ophthalmological presentation, although very evocative, is not always associated with systemic disease. The diagnosis of ocular sarcoidosis is then presumed in the absence of histological evidence. Algorithms combining ophthalmological and systemic signs have been proposed in cases of isolated uveitis. They make it possible to establish the diagnosis of ocular sarcoidosis with various levels of probability. The absence of significant granulomas on a systemic level during primary ocular involvement remains the main hypothesis to explain these diagnostic difficulties. Treatment is well described, as the uveitis of sarcoidosis is most often steroid responsive. In the case of corticosteroid-dependent uveitis, the first-line immunosuppressant remains methotrexate. The use of anti-tumor necrosis factor-alpha is an interesting alternative in patients whose ocular sarcoidosis is refractory to conventional immunosuppressants.


Assuntos
Sarcoidose , Adulto , Distribuição por Idade , Idoso , Corioidite/diagnóstico , Corioidite/epidemiologia , Diagnóstico Diferencial , Técnicas de Diagnóstico Oftalmológico , Endoftalmite/diagnóstico , Endoftalmite/epidemiologia , Granuloma/diagnóstico , Granuloma/epidemiologia , Humanos , Coroidite Multifocal , Vasculite Retiniana/diagnóstico , Vasculite Retiniana/epidemiologia , Sarcoidose/diagnóstico , Sarcoidose/epidemiologia , Sarcoidose/patologia , Uveíte/diagnóstico , Uveíte/epidemiologia
18.
Indian J Ophthalmol ; 67(3): 325-333, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30777946

RESUMO

Serpiginous choroiditis (SC) is an asymmetrically bilateral inflammation of the choroid that leads to loss of choriocapillaris atrophy or loss of overlying retinal pigment epithelium. Over the last few decades, SC has passed through a long evolution of nomenclature, etiologies and morphological variations. Initially diagnosed in patients with tuberculosis and syphilis, SC was predominantly considered as autoimmune process. With the advancement of molecular diagnosis, a new aspect of infectious subtypes of SC has emerged out. The terminologies such as serpiginous-like choroiditis (SLC) and multifocal serpiginoid choroiditis are now used to denote the subtypes of SC which are associated with infectious etiologies especially tuberculosis. In a country endemic for tuberculosis such as India, it is very important to differentiate between classic SC and SLC before initiating aggressive immunomodulatory therapy. Also, management of paradoxical worsening of the clinical condition with antitubercular treatment is another challenge in SLC and ophthalmologists should be aware of such situations. With advent of newer imaging modalities, monitoring the patient with choroiditis and identification of complications such as choroidal neovascular membrane have become much easier. This article aims to review the existing literature on SC with a special emphasis on management of SC and SLC.


Assuntos
Corioide/patologia , Corioidite/diagnóstico , Angiofluoresceinografia/métodos , Epitélio Pigmentado da Retina/patologia , Tomografia de Coerência Óptica/métodos , Diagnóstico Diferencial , Fundo de Olho , Humanos , Coroidite Multifocal
19.
Indian J Ophthalmol ; 67(3): 333-334, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30777947

Assuntos
Corioidite , Humanos
20.
BMC Ophthalmol ; 19(1): 39, 2019 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-30709392

RESUMO

BACKGROUND: Multifocal choroiditis (MFC) is multi-inflammatory lesions that occur in the retinal pigment epithelium (RPE) and the choriocapillaris. Optical examinations are the major diagnostic methods to diagnose the disease. OBJECTIVE: To examine patients with different types of MFC by multiple imageological methods. To summarize the imageology features of different types of MFC to make a medical examination guideline for clinician practices. METHOD: All of the patients who included in the study received examinations of fundus color photography, infrared fundus photography, fundus auto fluorescence (FAF), fluorescein fundus angiography (FFA), and optical coherence tomography (OCT), respectively. Finally, imageology features of different types of multifocal choroiditis were summarized. RESULTS: A total of 51 eyes from 28 patients with diagnosed MFC were included in the study. These patients consisted of 10 males and 18 females aged from 31 to 49 (mean age: 41.5 ± 0.8). 23 patients had MFC on both eye whilst 5 had monocular disease. The MFC lesions were classified as active inflammatory lesions, inactive inflammatory lesions, inflammatory lesions secondary active choroidal neovascularization (CNV) and inflammatory lesions secondary inactive CNV according to literature reports and comprehensive fundus imaging examinations. CONCLUSION: Examinations via fundus color photography, infrared fundus photography, FAF, FFA and OCT indicate typical imageological signals of different types of MFC. These imageology tests can greatly assist the clinicians to identify the MFC and provide proper therapies.


Assuntos
Corioidite/diagnóstico por imagem , Técnicas de Diagnóstico Oftalmológico , Adulto , Neovascularização de Coroide/complicações , Feminino , Angiofluoresceinografia/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Coroidite Multifocal , Fotografação/métodos , Epitélio Pigmentado da Retina/patologia , Estudos Retrospectivos , Tomografia de Coerência Óptica/métodos , Adulto Jovem
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