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1.
Indian J Dent Res ; 31(2): 217-223, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32436900

RESUMO

Background: The early enamel lesions are reversible as it is a process involving mineral transactions between the teeth and saliva. Aim: To evaluate the efficiency of three different tooth pastes on remineralization potential of initial enamel lesions using Vickers Micro hardness Test and Scanning electron microscopy. Materials and Methods: Artificial carious lesions were prepared in human enamel with demineralizing solution. The treatment agents included were Colgate sensitive plus® toothpaste, Regenerate enamel science™ toothpaste, BioRepair® toothpaste and control as Deionized water. All the samples were subjected to treatment solutions as per the pH cycling model for 12 days to simulate the daily oral environment's acid challenge. The remineralization parameters-surface hardness and surface roughness of enamel blocks were evaluated with Vickers indenter and Scanning electron microscope respectively. Statistical Analysis: ANOVA test was used to check mean differences between the groups. Post hoc analysis was done using Tukey's post hoc test. SEM images were graded according to Bonetti et al grading criteria. Results: As per statistical analysis, maximum remineralization of enamel blocks occurred after applying Colgate Sensitive Plus® tooth paste followed by BioRepair® tooth paste and Regenerate enamel Science™ toothpaste. Least remineralization potential was shown by control group. Conclusion: Colgate sensitive plus tooth paste with Pro Argin™ formula can be regarded as a potential remineralising agent. It can be concluded as a noninvasive means of managing early enamel carious lesions.


Assuntos
Remineralização Dentária , Cremes Dentais , Cariostáticos , Esmalte Dentário , Elétrons , Fluoretos , Dureza , Humanos , Microscopia Eletrônica de Varredura
2.
Stomatologiia (Mosk) ; 99(2): 40-44, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32441074

RESUMO

The aim of the study was to assess the efficacy of parodontax complex anti-inflammatory toothpaste with fluorine for treatment of moderate catarrhal gingivitis. MATERIAL AND METHODS: Within 6 weeks a group of students was observed, which was divided into 2 subgroups depending on the activity of the carious process and with characteristic changes in crystalloscopy of the oral fluid. Clinical trials of parodontax anti-inflammatory toothpaste with fluorine were conducted. The properties declared by the manufacturer were evaluated using clinical, biochemical, laboratory studies, and criteria-based assessment of crystalloscopic features of the oral fluid. RESULTS: The study revealed a statistically significant correlation of the cleaning ability of the hygiene product and crystalloscopic properties of saliva and changes in the clinical picture of chronic catarrhal gingivitis. With the inclusion of a comprehensive anti-inflammatory toothpaste containing fluorine and natural herbal extracts, a shift in the acid-base balance of the oral fluid to the alkaline side was recorded. CONCLUSION: The improvement in the oral hygiene indices and the resolution of inflammatory processes in periodontal tissues prove the efficacy of comprehensive treatment of chronic gingivitis including parodontax toothpaste.


Assuntos
Placa Dentária , Gengivite , Índice de Placa Dentária , Fluoretos , Humanos , Índice de Higiene Oral , Cremes Dentais
3.
Stomatologiia (Mosk) ; 99(2): 45-49, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32441075

RESUMO

THE AIM OF THE STUDY: Was to assess the stability of antioxidative activity of the active compound 2-ethyl-6-methylpiridine-3-ol succinate of toothpastes of the «Mexidol dent¼ line. MATERIALS AND METHODS: The study involved toothpastes of «MEXIDOL dent¼ line: MEXIDOL dent Aktiv MEXIDOL dent Complex, MEXIDOL dent Sensitive, MEXIDOL dent Fito, MEXIDOL dent Teens, MEXIDOL dent Professional White. Features of 2-ethyl-6-methylpiridine-3-ol succinate («MEXIDOL¼) determined the choice of potentiometric titration method for the assessment of the stability of antioxidative activity. RESULTS AND CONCLUSION: The study confirmed the stability of antioxidative activity of the active compound 2-ethyl-6-methylpiridine-3-ol succinate of toothpastes of the «Mexidol dent¼ line during shelf life.


Assuntos
Picolinas , Cremes Dentais , Adolescente , Antioxidantes , Humanos , Succinatos
4.
Stomatologiia (Mosk) ; 99(2): 91-96, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32441082

RESUMO

AIM: To design an algorithm of decreasing dentin hypersensitivity in children after professional oral hygiene. METHODS AND MATERIALS: Intact teeth extracted for orthodontic reasons in children and adults were involved in the pilot study. The enamel surface was cleaned by manual instruments and then polished with polishing pastes containing sodium bicarbonate, fluoride, calcium and phosphates. The results were studied with the help of a scanning electronic microscope. 60 14-15 years schoolchildren, the residents of Krasnogorsk, a town in the Moscow region, took part in the study. All of them were diagnosed dental plaque (K03.6) and underwent professional oral hygiene by manual instruments. Then the teeth were polished with polishing toothpastes. To reduce dentin hypersensitivity after these procedures the SENSODYNE Rapid Relief toothpaste was applied. RESULTS: The pilot study showed a destructive effect of a manual instrument on the tooth enamel especially in children. The data of the scanning electronic microscope demonstrated that the manual method with the use of polishing pastes containing sodium bicarbonate, fluoride, calcium and phosphates led to a significantly lower negative effect of this manual method on the tooth enamel both in children and adults. The application of SENSODYNE Rapid Relief by children at home after professional oral hygiene led to a decrease of dentin hypersensitivity by 65, 37%. CONCLUSION: The designed algorithm of the children's follow-up procedures after professional oral hygiene includes the application of polishing pastes containing sodium bicarbonate, fluoride, calcium, phosphates and the Sensodyne Rapid Relief toothpaste at home. This helps to minimize negative consequences of manual tooth plaque removal in case of professional oral hygiene.


Assuntos
Dessensibilizantes Dentinários , Sensibilidade da Dentina , Adulto , Arginina , Carbonato de Cálcio , Criança , Método Duplo-Cego , Fluoretos , Humanos , Moscou , Higiene Bucal , Fosfatos , Projetos Piloto , Fluoreto de Sódio , Escovação Dentária , Cremes Dentais , Resultado do Tratamento
5.
J Appl Oral Sci ; 28: e20190163, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32236351

RESUMO

OBJECTIVE: This in vitro study evaluated the effect of commercial whitening dentifrices on erosive tooth wear (ETW) of bovine enamel samples, in comparison with commercial regular dentifrices. METHODOLOGY: Sixty bovine crowns were embedded in acrylic resin, polished and then had their baseline profile determined. They were randomly assigned to 5 groups (n=12/group), according to the type of commercial dentifrice to be tested: GI - Crest Anti-cavity Regular; GII - Crest 3D White; GIII - Colgate Total 12 Clean Mint; GIV - Colgate Optic White; GV - Placebo (negative control, fluoride-free dentifrice). The samples were submitted to daily erosive and abrasive challenges for 3 days. The erosive challenges were performed 3 times a day by immersing the specimens in 0.1% citric acid solution (pH 2.5) for 90 s. Each day after the first and last erosive challenges, the specimens were subjected to the abrasive challenge for 15 s, using a toothbrushing machine (Biopdi, São Carlos, SP, Brazil), soft toothbrushes and slurry (1:3 g/ml) of the tested toothpastes (1.5 N). The specimens were kept in artificial saliva between the challenges. The final profile was obtained and the ETW (µm) was calculated. Data were analyzed by Kruskal-Wallis and Dunn's tests (p<0.05). RESULTS: All dentifrices tested significantly reduced the enamel wear in comparison with the Placebo, except GIII. The median (95% CI) ETW was 1.35 (1.25-1.46)bc for GI, 1.17 (1.01-1.34)cd for GII, 1.36 (1.28-1.45)ab for GIII, 1.08 (1.04-1.14)d for GIV and 2.28 (2.18-2.39)a for GV. CONCLUSION: When dentifrices from the same manufacturer were compared, the whitening dentifrices led to similar or less wear than the regular ones.


Assuntos
Esmalte Dentário/efeitos dos fármacos , Clareadores Dentários/efeitos adversos , Erosão Dentária/induzido quimicamente , Cremes Dentais/efeitos adversos , Animais , Bovinos , Esmalte Dentário/química , Teste de Materiais , Estatísticas não Paramétricas , Propriedades de Superfície , Fatores de Tempo , Clareadores Dentários/química , Escovação Dentária/efeitos adversos , Cremes Dentais/química
6.
Stomatologiia (Mosk) ; 99(1): 7-11, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32125295

RESUMO

PURPOSE: To determine the effect of whitening toothpastes on the color of a nanocomposite material using a spectrophotometer. MATERIAL AND METHODS: The study involved 50 samples from nanocomposite restoration material which were exposed under laboratory conditions to brushing with one of 4 types of toothpastes (control with no bleaching agents, peroxide paste with carbamide, abrasive and enzyme-based pastes). Using the parameters a, b and L obtained by spectrophotometry, delta E (ΔE) value was calculated. To determine the maximum and minimum A posteriori comparisons by the Scheffe method were used to influence the delta E parameter after exposure to the pastes. Oxygen-containing paste (OZPP) had a maximum effect on the increase of the ΔE parameter, ΔE=1.03 comparing to ΔE=0.20 in control toothpaste. The isolated effect of a toothbrush resulted in a large change in the parameter ΔE, compared to the effect of a controls. However, the ΔE does not indicate the clarification of the material, but only a change in color relative to the initial measurement. As a result of spectrophotometry and statistical data processing, it was found that all pastes had a sufficient effect on the color change for the device to determine, but this change was not noticeable to the human eye.


Assuntos
Nanocompostos , Clareadores Dentários , Clareamento Dental , Humanos , Espectrofotometria , Cremes Dentais
7.
Stomatologiia (Mosk) ; 99(1): 27-32, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32125298

RESUMO

The purpose of the study is a comparative assessment of hygiene products recommended for increased sensitivity of teeth and having an anti-inflammatory effect on periodontal tissue. The study involved 40 people aged 55-65 years with hyperesthesia and chronic mild and moderate periodontitis, which were divided into 2 groups (20 people each) depending on the toothpastes used based on HAP. Over time, indicators of hygiene, sensitivity, bleeding, PMA indices and the periodontal probing depth are evaluated. The study revealed an improvement of the studied indices in both groups after two weeks of using toothpastes. Both of the studied toothpastes lead to a decrease in hyperesthesia and relief of inflammation, which makes it possible to conduct high-quality oral hygiene. However, a more significant improvement in clinical signs was observed when using paste plant components and bifidobacteria extract. Thus, in the complex therapy of inflammatory periodontal diseases accompanied by hyperesthesia, both studied pastes can be recommended for at least 14 days.


Assuntos
Doenças Periodontais , Periodontite , Idoso , Humanos , Hiperestesia , Pessoa de Meia-Idade , Higiene Bucal , Cremes Dentais
8.
J Dent Child (Chic) ; 87(1): 31-38, 2020 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-32151308

RESUMO

Purpose: To describe toothbrushing frequency/duration and toothpaste use among young children in an urban, vulnerable population in Chicago, Ill., USA.
Methods: Caregivers of children younger than three years old were recruited from university and community pediatric dental clinics. Caregivers completed a 37-item questionnaire in English or Spanish about predictors/covariates (demographics, child/caregiver oral health, access to dental care) and primary outcomes (child toothbrushng behaviors, toothpaste use). Models employed generalized logit and ordinal logistic regression.
Results: A total of 148 caregivers completed the survey. The average child age was 18.8 months (±7.4 SD). Approximately 41 percent of children brushed once a day or less, and 19 percent of caregivers did not regularly assist. Almost all children used toothpaste (96 percent), but 36 percent of caregivers did not know if it contained fluoride. Increased child brushing frequency was associated with older child age, higher caregiver brushing frequency, history of a child dental visit, and caregiver assistance (P<0.05). Children with a history of dental visits were seven times more likely to brush for 30 seconds or more, and receiving caregiver assistance was associated with brushing longer than two minutes (P <0.05).
Conclusion: Most children brushed at least once daily and nearly all of them used toothpaste. Access to dental care, parental involvement, and parental oral health were associated with favorable child toothbrushing behaviors. Toothbrushing duration, frequency, and encouraging family assistance are modifiable protective factors and opportunities for intervention.


Assuntos
Escovação Dentária , Cremes Dentais , Chicago , Criança , Pré-Escolar , Fluoretos , Humanos , Saúde Bucal
9.
Oral Health Prev Dent ; 18(1): 53-59, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32051971

RESUMO

PURPOSE: To investigate dental enamel wear caused by erosion and abrasion while using a combination of anti-erosive toothbrush/-paste. MATERIALS AND METHODS: A total of 60 enamel specimens from bovine incisors were randomly assigned into five groups of 12 specimens each (G1-5, n = 12): (G1) control group (no treatment), (G2) standard medium toothbrush Paro M43 and standard toothpaste Elmex Caries Protection, (G3) standard medium toothbrush Paro M43 and anti-erosive toothpaste Elmex Protection Erosion, (G4) anti-erosive toothbrush Elmex Erosion Soft and standard toothpaste Elmex Caries Protection, (G5) anti-erosive toothbrush Elmex Erosion Soft and anti-erosive toothpaste Elmex Protection Erosion. Initially, surface baseline profiles were recorded using profilometry. In a total of 60 cycles, all specimens were exposed to hydrochloric acid (pH = 3) for 1 min, rinsed with tap water to stop the erosive attack and brushed according to the specific protocol of each group (15 brushing strokes per run). Enamel loss was determined by comparing the surface profiles before and after 60 cycles and the results were statistically analysed using analysis of variance (ANOVA). RESULTS: The significantly highest loss of enamel was observed in the control group G1(1.4 ± 0.20 µm) (p < 0.001). G2 turned out to be the most abrasive toothbrush/-paste combination (1.12 ± 0.15 µm), G3 the least invasive (0.40 ± 0.04 µm) (p < 0.001, respectively). CONCLUSION: All combinations of the investigated toothbrushes/-pastes reduce erosive/abrasive enamel wear. However, the highest reduction was observed for the combination of anti-erosive toothpaste and standard toothbrush (G3).


Assuntos
Abrasão Dentária , Erosão Dentária , Animais , Bovinos , Esmalte Dentário , Escovação Dentária , Cremes Dentais
10.
J Oral Sci ; 62(1): 103-106, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31996511

RESUMO

This study aims to evaluate the effect of mouth rinses on the color, microhardness, and surface roughness of tooth enamel. Sixty dental blocks were collected from human third molars and divided in five groups (n = 12): the control group (CG) without immersion in mouth rinse, Listerine Zero, Colgate Plax Fresh Mint, Listerine Whitening, and Colgate Luminous White. The groups were subjected to initial color analysis; the microhardness and roughness of the enamel surfaces were evaluated. Next, the samples were subjected to immersion in mouth rinses or brushing with conventional fluoride toothpaste (CG) according to the manufacturer's instructions; after a 12-week treatment, the color, microhardness, and roughness were once again assessed and compared with the initial analysis. Data were tabulated and analyzed through a two-way analysis of variance (ANOVA) (color and roughness) followed by Tukey's test. Microhardness was analyzed through the Kruskal-Wallis test followed by Dunn's test; the level of significance was 5%. All groups immersed in mouth rinses had a higher level of microhardness loss than CG; additionally, all groups showed changes in the enamel surface. Enamel surface loss was observed using a roughness test, and the mouth rinses promoted a higher level of color changes than CG. Given the results, it can be concluded that the mouth rinses led to significant changes in tooth enamel.


Assuntos
Clareamento Dental , Dente , Esmalte Dentário , Humanos , Antissépticos Bucais , Cremes Dentais
11.
Monogr Oral Sci ; 28: 32-47, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31940644

RESUMO

Microelements are essential components of the diet. This chapter describes the effect of several such elements: zinc, copper, iron, tin, and iodine, on oral health. As part of normal diets, these elements have limited associations with specific oral conditions. This is partly because of their presence at relatively low concentrations and partly because they are most often present as mixtures where the effect of any one element is confounded by others. Deficiencies in microelements can cause health problems. Hence supplements, often containing one or more microelements, are prescribed to combat such conditions. All these ions exhibit antibacterial properties. Such effects are invariably small at the concentrations found in conventional foods and drinks. However, at higher concentrations, these ions can inhibit acid production by plaque bacteria involved in dental caries. Of more importance, zinc and tin have potentially significant effects on the de- and remineralisation processes involved in dental caries. Indeed, both elements have been included in oral hygiene products such as toothpastes for many years. Zinc, in particular, has demonstrated not only the ability to reduce dissolution rates of enamel and hydroxyapatite but also to inhibit calculus formation. Tin can also markedly reduce the dissolution rates. Both Cu and Fe have demonstrated anti-caries effects in animal models, whilst Fe-containing drinks have been shown to reduce enamel erosion in situ. The broad spectrum antibacterial properties of iodine have been promoted for its potential use against both early childhood caries and chronic periodontitis. However, more convincing clinical research is required to validate efficacy.


Assuntos
Cárie Dentária , Placa Dentária , Animais , Esmalte Dentário , Cremes Dentais , Zinco
12.
Arch Oral Biol ; 110: 104619, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31805483

RESUMO

OBJECTIVE: The aim of this study was to evaluate the morphological and chemical effect of in-office and at-home desensitising agents containing sodium fluoride (NaF) on eroded root dentine in vitro. METHODS: Fifty bovine dentine samples were pre-eroded and randomised into five groups (n = 10): G1 (Control) - milli-Q water; G2 - fluoride varnish containing NaF 22,500 ppm; G3 - desensitising cream containing NaF 9,000 ppm associated with 20% nanohydroxyapatite; G4 - toothpaste with NaF 5,000 ppm associated to tricalcium phosphate; G5 - toothpaste containing NaF 900 ppm and casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF). The specimens were submitted to erosive challenge for three days. The analyses were performed using non-contact profilometry for volumetric (Sa) and linear roughness (Ra) followed by scanning electron microscopy (SEM) and Energy Dispersive X-ray Spectrometry (EDS). The data were analysed by Kruskal-Wallis and Wilcoxon tests (α = 0.05). RESULTS: There was a significant reduction of Ra and Sa for the eroded samples from the G2 and G5 (p < 0.05) after an erosive challenge. The dentine surface topography pattern showed partially or totally occluded dentinal tubules after treatments, except in the control group. The control, G4 and G3 groups showed a reduction in the dentine inorganic content percentage of Ca (Calcium) and P (Phosphorus) minerals. CONCLUSION: The fluoride varnish and CPP-ACPF toothpaste were able to prevent morphological changes and were the only materials that showed the Ca and P content increased after treatment. These materials may be promising alternatives in the clinical control of dentin erosion.


Assuntos
Dentina , Fluoreto de Sódio , Erosão Dentária , Raiz Dentária , Animais , Bovinos , Dentina/efeitos dos fármacos , Fluoretos , Fluoreto de Sódio/farmacologia , Erosão Dentária/tratamento farmacológico , Raiz Dentária/efeitos dos fármacos , Cremes Dentais
13.
Arch Oral Biol ; 109: 104549, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31541844

RESUMO

OBJECTIVE: This in vitro study aimed to evaluate different periods of exposure to clarified human saliva for the ability to protect enamel against erosive tooth wear. METHODS: For this purpose, sixty specimens (4 × 4 × 1.5 mm) were prepared from third human molars. For all groups, the period before abrasion was performed by remineralisation with human saliva (except in G1). The specimens were randomly divided into six groups (n = 10) according to the different remineralisation times of exposure to clarified human saliva: no exposure to saliva (G1) and 30 min (G2), 60 min (G3), 90 min (G4), 120 min (G5), and 240 min (G6) of exposure to human saliva. A 5-day cycling was performed with 5 min of erosion (1% citric acid; pH 2.3), 4x/day. After the first and last erosive episodes, the abrasion challenge was performed with slurry of fluoride toothpaste (1450 ppm F-, as sodium monofluorophosphate) plus human saliva (1:3), with an electric toothbrush (15 s, with a total of 120 s of slurry immersion). Surface loss (SL) was determined using an optical profilometer (n = 10) and for qualitative analysis, environmental scanning electron microscopy (ESEM) was performed (n = 3). The SL data were statistically analysed by one-way analysis of variance (α = 0.05). RESULTS: No significant differences were detected among the groups for SL (p > 0.05), and ESEM showed similar aspects of eroded enamel. CONCLUSIONS: The period of in vitro exposure to clarified human saliva was not able to protect against enamel erosion.


Assuntos
Esmalte Dentário/patologia , Saliva/química , Abrasão Dentária , Erosão Dentária , Humanos , Distribuição Aleatória , Escovação Dentária/instrumentação , Cremes Dentais
14.
Arch Oral Biol ; 109: 104580, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31593890

RESUMO

OBJECTIVES: This study evaluated the erosive tooth wear promoted by commercial whitening toothpastes on eroded dentin in vitro. DESIGN: Ninety bovine roots were embedded, polished and subjected to the baseline profile analysis. The samples were protected in 2/3 of the dentin surface and were randomly assigned to 6 groups (n = 15/group): Oral-B 3D White; Close-up Diamond Attraction Power White; Sorriso Xtreme White 4D; Colgate Luminous White; Crest and erosion only. All samples were submitted to erosive pH cycles (4 × 90 s in 0.1% citric acid, pH 2.5, per day) and abrasive challenges (2 × 15 s, per day) for 7 days. The samples were subjected to abrasion, using toothbrushing machine, soft toothbrushes and slurries of the tested toothpastes (1.5 N, 1:3 water). Between the challenges, the samples were immersed in artificial saliva. The final profile was overlaid to the baseline profile for the calculation of the erosive dentin wear (µm). The data were subjected to Kruskal-Wallis/Dunn tests (p < 0.05). RESULTS: Colgate Luminous White (4.7 µm) and Sorriso Xtreme White 4D (4.0 µm) promoted the highest wear, similarly to Oral-B 3D White (2.3 µm). Oral-B 3D White promoted similar wear compared to Crest (1.1 µm) and Close-up Diamond Attraction Power White (1.2 µm); however, it induced significant higher dentin wear compared to erosion only (1.0 µm). Close-up Diamond Attraction Power White and Crest did not increase the erosive wear compared to erosion only. CONCLUSION: Some whitening toothpastes increase the wear of eroded dentin, which should be considered by the dentist when prescribing them to patient with root exposure.


Assuntos
Dentina , Abrasão Dentária , Erosão Dentária , Cremes Dentais/efeitos adversos , Animais , Bovinos , Distribuição Aleatória , Escovação Dentária
15.
Braz Oral Res ; 33: e114, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31800865

RESUMO

This in vitro study aimed to evaluate the effect of different toothpastes on dental enamel subjected to an erosive cycle with and without exposure to cigarette smoke. Bovine enamel specimens were randomly allocated into 12 groups (n = 12). For the in vitro simulation of smoking, half the groups underwent an exposure cycle of 20 cigarettes per day for 5 days. Subsequently, all groups were subjected to a 5-day erosion cycle intercalating demineralization (1 min; 1% citric acid; pH = 3.5) and treatment with toothpaste slurries (2 min) of NaF, SnF2, F/Sn/Chitosan, F/CaSiO3/Na3PO4, and F/bioactive glass. The control group was immersed in distilled water. Surface microhardness (SMH) was measured initially, after exposure to smoke, and after the erosive cycle, and %SMH was calculated. At the end of the experimental cycle, surface roughness, profilometry, and atomic force microscopy (AFM) were performed. SMH increased after exposure to cigarette smoke (p < 0.05). After the erosive cycle, there were no differences between the presence and absence of cigarette smoke exposure in SMH and roughness (p > 0.05). Besides increasing enamel SMH, cigarette smoke did not prevent enamel loss after the erosion cycle (p < 0.05). In profilometry, roughness and surface loss had the lowest values in the groups treated with SnF2 and F/Sn/Chitosan (p < 0.05). AFM showed lower mineral loss with F/CaSiO3/Na3PO4 and F/Sn/Chitosan. For all groups, except F/CaSiO3/Na3PO4, cigarette smoke resulted in higher enamel wear. F/Sn/Chitosan showed the best results against erosion.


Assuntos
Fumar Cigarros/efeitos adversos , Esmalte Dentário/efeitos dos fármacos , Erosão Dentária/etiologia , Erosão Dentária/prevenção & controle , Cremes Dentais/uso terapêutico , Animais , Compostos de Cálcio/uso terapêutico , Cariostáticos/uso terapêutico , Bovinos , Quitosana/uso terapêutico , Testes de Dureza , Humanos , Microscopia de Força Atômica , Valores de Referência , Reprodutibilidade dos Testes , Saliva/química , Silicatos/uso terapêutico , Propriedades de Superfície/efeitos dos fármacos , Fatores de Tempo , Fluoretos de Estanho/uso terapêutico , Desmineralização do Dente/induzido quimicamente , Desmineralização do Dente/prevenção & controle , Água/química
16.
J Contemp Dent Pract ; 20(10): 1206-1211, 2019 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-31883258

RESUMO

AIM: "Tocosh" is a potato that has undergone a process of hydraulic oxidation that enhances its antimicrobial properties so that this natural resource can be used in medical sciences. The aim of this study was to develop and evaluate the antibacterial and cytotoxic activity of a new experimental tooth based on Solanum tuberosum "Tocosh" on the cell lines 3T3 and DU145. MATERIALS AND METHODS: To evaluate the cytotoxicity, cell cultures 3T3 and DU145 were used. Cell viability was determined by the MTT assay (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) in a medium containing 10% calf serum where the cells were preincubated at a concentration of 1 × 106 cells/mL in culture medium for 3 hours at 37°C and 6.5% CO2. Then, the absorbance was measured using a microplate reader where the formazan crystals were diluted with acidic and cold isopropanol, and quantified in an ELISA reader. To evaluate the antibacterial effect, the Kirby Bauer inhibition halos method was used on strains of S. aureus (ATCC 25923), S. mutans (ATCC 25175), and S. mitis (ATCC 49456). RESULTS: Solanum tuberosum (tocosh) was not cytotoxic because it only had one CC50 at the concentration of 0.26927 mg/mL and 0.26845 mg/mL for the cell lines 3T3 and DU145, respectively. Tocosh toothpaste (TD) has an antibacterial effect against S. aureus and S. mutans. CONCLUSION: The new ecological dentifrice was not cytotoxic since it did not alter cell viability because its CC50 was only 0.268 and 0.269 µg/mL for the 3T3 and DU145 cell lines, respectively; however, it presented an optimal antimicrobial activity against the oral strains evaluated. CLINICAL SIGNIFICANCE: This research has great potential for clinical use because this new dentifrice has antimicrobial activity against different oral germs. How to cite this article: Mayta-Tovalino F, Sedano-Balbin G, Romero-Tapia P, et al. Development of New Experimental Dentifrice of Peruvian Solanum tuberosum (Tocosh) Fermented by Water Stress: Antibacterial and Cytotoxic Activity. J Contemp Dent Pract 2019;20(10):1206-1211.


Assuntos
Dentifrícios , Solanum tuberosum , Antibacterianos , Desidratação , Humanos , Testes de Sensibilidade Microbiana , Peru , Staphylococcus aureus , Cremes Dentais
17.
Rev. cuba. estomatol ; 56(4): e1825, oct.-dez. 2019. tab
Artigo em Espanhol | LILACS | ID: biblio-1093247

RESUMO

RESUMEN Introducción: Durante la gestación, algunos cambios fisiológicos en la mujer propician un incremento de la placa dental y de la microbiota cariogénica. Esta condición unida a una modificación de la dieta y a una inadecuada higiene bucal condicionarían desfavorablemente la salud oral tanto de la madre como del bebé. Objetivo: Determinar el efecto antibacteriano de una pasta dental con xilitol sobre el recuento de Streptococcus mutans en saliva de gestantes. Métodos: Ensayo clínico, a doble ciego, que se realizó en el Centro de Salud "José Olaya" (Chiclayo Perú), en enero de 2017. Se trabajó con una población muestral de 50 gestantes en el segundo trimestre que cumplieron con los criterios establecidos. Se crearon dos grupos: 25 gestantes usaron dentífrico con 10 por ciento de xilitol y 25 gestantes usaron dentífrico sin xilitol. Se les tomó y proceso microbiológicamente una muestra de saliva antes del inicio del estudio y 14 días después del uso de las respectivas pastas. Se realizó el recuento de unidades formadoras de colonias de Streptococcus mutans en saliva con una confiabilidad altamente significativa mediante el coeficiente de correlación intraclase, calibración intra e interexaminador (1,000 y 0,999, respectivamente). El análisis de los datos se realizó mediante la prueba U de Mann-Whitney, considerando un nivel de significancia del 5 por ciento. Resultados: No se encontró diferencia significativa entre las gestantes que emplearon pasta dental con xilitol en comparación con las que utilizaron pasta dental sin xilitol (p= 0,062). Conclusiones: El efecto antibacteriano de la pasta dental comercial con xilitol es similar a una pasta dental sin xilitol sobre el recuento de Streptococcus mutans en saliva de gestantes(AU)


ABSTRACT Introduction: Some physiological changes occur in women during pregnancy which cause an increase in dental plaque and cariogenic microbiota. This situation, alongside a modification in the diet and inadequate oral hygiene, negatively affect the oral health of both the mother and the baby. Objective: Determine the antibacterial effect of a toothpaste with xylitol on the count of Streptococcus mutans in pregnant women's saliva. Methods: A double-blind clinical trial was conducted in José Olaya Health Center (Chiclayo, Peru) in January 2017. The sample population was 50 women in the second trimester of pregnancy who met the established inclusion criteria. Two groups were formed: 25 pregnant women used a toothpaste with 10 percent xylitol and the other 25 used a toothpaste without xylitol. A saliva sample was taken and processed microbiologically before the start of the study and 14 days after use of the two toothpastes. A count was performed of colony-forming units for Streptococcus mutans in saliva with highly significant reliability, using the intraclass correlation coefficient, and intra- and inter-rater calibration (1.000 and 0.999, respectively). Data analysis was based on the Mann-Whitney U Test, with a significance level of 5 percent. Results: No significant difference was found between the pregnant women who used the toothpaste with xylitol and those who used the toothpaste without xylitol (p= 0.062). Conclusions: The antibacterial effect of the commercial toothpaste with xylitol is similar to that of a toothpaste without xylitol in terms of the Streptococcus mutans count in pregnant women's saliva(AU)


Assuntos
Humanos , Feminino , Gravidez , Streptococcus mutans/citologia , Cremes Dentais/administração & dosagem , Placa Dentária/epidemiologia , Antibacterianos/uso terapêutico
18.
J Evid Based Dent Pract ; 19(4): 101337, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31843175

RESUMO

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Effect of desensitizing toothpastes on dentine hypersensitivity: A systematic review and meta-analysis. Hu M-L, Zheng G, Zhang Y-D, Yan X, Li X-C, Lin H. J Dent (2018)75:12-21. SOURCE OF FUNDING: The authors reported that this research did not receive any specific funding from the public, commercial, or not-for-profit sectors. TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data.


Assuntos
Dessensibilizantes Dentinários , Sensibilidade da Dentina , Fosfatos de Cálcio , Dentina , Fluoretos , Humanos , Estrôncio , Cremes Dentais
19.
J Evid Based Dent Pract ; 19(4): 101349, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31843182

RESUMO

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Effect of sodium lauryl sulfate on recurrent aphthous stomatitis: A systematic review. Alli BY, Erinoso OA, Olawuyi AB. J Oral Pathol Med. 2019;48(5):358-64. SOURCE OF FUNDING: None. The authors declared no conflict of interest. TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data from double-blind randomized controlled trials.


Assuntos
Dentifrícios , Estomatite Aftosa , Método Duplo-Cego , Humanos , Dodecilsulfato de Sódio , Cremes Dentais
20.
Am J Dent ; 32(5): 245-250, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31675193

RESUMO

PURPOSE: To compare the efficacy of toothpaste containing surface pre-reacted glass-ionomer (S-PRG) filler particles to that of conventional sodium fluoride (NaF) toothpaste for the prevention of dentin demineralization and biofilm regrowth. METHODS: Bovine root dentin specimens and glass coverslips were used as biofilm growth substrates. To establish biofilms, glass and dentin specimens were incubated for 72 hours in 0.2% sucrose McBain medium inoculated with stimulated saliva from a single donor. Specimens then received a single 5-minute treatment with S-PRG toothpaste, fluoride toothpaste, or sterilized deionized water and were incubated in McBain medium for 120 hours to allow biofilm regrowth. Output parameters during regrowth (72-192 hours) were pH of spent medium, colony-forming unit (CFU) counts of biofilms, and dentin mineral profiles, integrated mineral loss (IML: vol% × µm), and lesion depth (Ld). Treatment group differences were tested by one-way ANOVA followed by Tukey's multiple range test (P< 0.05). RESULTS: At 144 hours, medium pH was significantly higher in the S-PRG-treated dentin group than in the NaF-treated dentin group. In addition, at 192 hours, the CFU count, IML, and Ld were lower in the S-PRG-treated dentin group than in the NaF-treated dentin group. There were significant differences of pH among dentin groups at 72 hours. Treatment with S-PRG toothpaste markedly inhibited dentin demineralization compared to that with NaF toothpaste. CLINICAL SIGNIFICANCE: Toothpaste containing multiple ions-releasing filler suppressed bacterial viability and inhibited dentin demineralization.


Assuntos
Desmineralização do Dente , Cremes Dentais , Animais , Biofilmes , Bovinos , Dentina , Fluoretos
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