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1.
Braz. j. biol ; 84: e257969, 2024. tab, ilus
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1364513

RESUMO

In this study, we evaluated variation in vegetative and reproductive phenological events of four phylogenetically related plant species subjected to a seasonal environment. To this aim, we sampled 15 individuals of each plant species every fortnight for one year, between January and December of 2017. To assess when a given phenophase occurred more intensely in the population, the Fournier intensity index was used and the synchrony of individuals of the sample in a given phenological event was estimated using the activity index. The Rayleigh (Z) test was used to determine whether the phenological events have seasonal distribution. The relationship of abiotic factors (photoperiod, precipitation, relative humidity and temperature) with the intensity of phenophases was evaluated for each plant species using generalized linear models (GLMs). The phenophases of all plants showed a seasonal distribution pattern, as well as variation in synchrony of phenophases and specific sets of abiotic factors significantly influenced their phenophases. New leaves, for example, were produced throughout the seasons, with intense leaf fall in the dry season. Flowering periods, on the other hand, did not overlap. Indeed, species exhibited sequential flowering and asynchronous flowering among individuals. Our results suggest that the phenological patterns of four sympatric plant species are directly linked to climatic variables, but different abiotic factors affected different phenophases.


Neste estudo, avaliamos a variação nos eventos fenológicos vegetativos e reprodutivos de quatro espécies de plantas filogeneticamente relacionadas submetidas a um ambiente sazonal. Para isso, amostramos 15 indivíduos de cada espécie quinzenalmente, pelo período de um ano, entre janeiro e dezembro de 2017. Para avaliar quando uma determinada fenofase ocorreu de modo mais intenso na população foi utilizado o índice de intensidade de Fournier e a sincronia dos indivíduos da amostra em determinado evento fenológico foi estimada utilizando-se o índice de atividade. O teste de Rayleigh (Z) foi usado para determinar se os eventos fenológicos têm distribuição sazonal. A relação dos fatores abióticos (fotoperíodo, precipitação, temperatura e umidade relativa) com a intensidade das fenofases foi avaliada para cada espécie de planta usando modelos lineares generalizados (GLMs). As fenofases de todas as plantas apresentaram um padrão de distribuição sazonal, bem como variação na sincronia das fenofases e conjuntos específicos de fatores abióticos influenciaram significativamente suas fenofases. Folhas novas, por exemplo, foram produzidas ao longo das estações, com intensa queda de folhas na estação seca. Os períodos de floração, por outro lado, não se sobrepuseram. De fato, as espécies exibiram floração sequencial e floração assíncrona entre os indivíduos. Nossos resultados sugerem que os padrões fenológicos das quatro espécies de plantas simpátricas estão diretamente ligados às variáveis climáticas, mas diferentes fatores abióticos afetaram diferentes fenofases.


Assuntos
Plantas , Estações do Ano , Crescimento e Desenvolvimento , Meio Ambiente , Simpatria/fisiologia
2.
J Anim Sci ; 1012023 Jan 03.
Artigo em Inglês | MEDLINE | ID: mdl-36592744

RESUMO

Changes in the environment, including nutritional changes, can influence fetal and postnatal development of the offspring, which can result in differences in growth, metabolism, reproduction, and health later in life. In beef cattle research on energy and protein restriction during late gestation appears to be contradictory. Therefore, in this review, we will examine the nutrient requirements recommended for this period. We are summarizing contradictory data on effects on offspring performance with possible explanations of the reason for why the data seems contradictory. We will finish by discussing some areas that we consider important for further research to increase the knowledge on how maternal nutrition influences offspring development. In particular, suggestions are provided on the need for more accurately measuring nutrient and energy supply and use and the impact on subsequent epigenetic effects. This will improve understanding of nutritional effects during gestation on offspring performance.


The objective of this review is to summarize the current knowledge on the effect of protein and energy restriction during the last third of gestation to beef cows on growth performance of offspring, focusing principally on Bos taurus cows. We divided the review in three sections: 1) evaluating the current beef cow requirements, highlighting areas in need of a more current research, 2) demonstrating some inconsistency on growth and carcass characteristics variables due to energy and protein restriction in late gestation, and 3) offering our opinion on future research in the area.


Assuntos
Fenômenos Fisiológicos da Nutrição Materna , Nutrientes , Feminino , Gravidez , Bovinos , Animais , Feto , Reprodução , Crescimento e Desenvolvimento , Dieta/veterinária , Fenômenos Fisiológicos da Nutrição Animal , Ração Animal/análise
3.
PLoS One ; 18(1): e0279826, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36696393

RESUMO

Pollen allergy becomes an increasing problem for humans, especially in the regions, where the air pollution level increases due to the traffic and urbanization. These factors may also affect the physiological activity of plants, causing changes in pollen allergenicity. The aim of the study was to estimate the influence of air pollutants on the chemical composition of birch pollen and the secondary structures of the Bet v1 protein. The research was conducted in seven locations in Malopolska region, South of Poland of a different pollution level. We have found slight fluctuations in the values of parameters describing the photosynthetic light reactions, similar spectra of leaf reflectance and the negligible differences in the discrimination values of the δ13C carbon isotope were found. The obtained results show a minor effect of a degree of pollution on the physiological condition B. pendula specimen. On the other hand, mean Bet v1 concentration measured in pollen samples collected in Kraków was significantly higher than in less polluted places (p = .03886), while FT-Raman spectra showed the most distinct variations in the wavenumbers characteristic of proteins. Pollen collected at sites of the increased NOx and PM concentration, show the highest percentage values of potential aggregated forms and antiparallel ß-sheets in the expense of α-helix, presenting a substantial impact on chemical compounds of pollen, Bet v1 concentration and on formation of the secondary structure of proteins, what can influence their functions.


Assuntos
Poluição do Ar , Alérgenos , Humanos , Alérgenos/química , Pólen/química , Betula , Crescimento e Desenvolvimento , Antígenos de Plantas
4.
Int J Mol Sci ; 24(2)2023 Jan 12.
Artigo em Inglês | MEDLINE | ID: mdl-36675002

RESUMO

Fasciclin-like arabinogalactan proteins (FLAs) are a subclass of arabinogalactan proteins (AGPs) containing both AGP-like glycated domains and fasciclin (FAS) domains, which are involved in plant growth and development and synthesis of the cell wall. However, these proteins have not been identified or analyzed in willow, Salix, the sister genus of Populus. In this study, we performed a whole genome study of the FLA gene family of Salix suchowensis and compared it with the FLA gene family of Populus deltoides. The results showed the presence of 40 and 46 FLA genes in P. deltoides and S. suchowensis, distributed on 17 and 16 chromosomes, respectively. Four pairs of tandem repeat genes were found in willow, while poplar had no tandem repeat genes. Twelve and thirteen pairs of duplicated gene fragments were identified in poplar and willow, respectively. The multispecies phylogenetic tree showed that the FLA gene family could be divided into four groups (I-IV), with Group 1 showing significant expansion in woody plants. A gene expression analysis showed that PdeFLA19/27 in Group I of poplar was highly expressed, specifically during the secondary growth period of the stem and the rapid elongation of seed hairs. In the Group I genes of S. suchowensis, SsuFLA25/26/28 was also highly expressed during the secondary growth period, whereas increased expression of SsuFLA35 was associated with seed hair tissue. These results provide important clues about the differences in the FLA gene family during the evolution of herbs and woody plants, and suggest that the FLA gene family may play an essential role in regulating the secondary growth of woody plants. It also provides a reference for further studies on the regulation of secondary growth and seed hair development by FLA genes in poplar and willow.


Assuntos
Proteínas de Plantas , Populus , Filogenia , Proteínas de Plantas/genética , Proteínas de Plantas/metabolismo , Plantas/metabolismo , Crescimento e Desenvolvimento , Regulação da Expressão Gênica de Plantas , Populus/genética , Populus/metabolismo
5.
J Theor Biol ; 560: 111373, 2023 Mar 07.
Artigo em Inglês | MEDLINE | ID: mdl-36509139

RESUMO

A principal objective in agriculture is to maximise food production; this is particularly relevant with the added demands of an ever increasing population, coupled with the unpredictability that climate change brings. Further improvements in productivity can only be achieved with an increased understanding of plant and crop processes. In this respect, mathematical modelling of plants and crops plays an important role. In this paper we present a two-scale mathematical model of crop yield that accounts for plant growth and canopy interactions. A system of nonlinear ordinary differential equations (ODEs) is formulated to describe the growth of each individual plant, where equations are coupled via a term that describes plant competition via canopy-canopy interactions. A crop of greenhouse plants is then modelled via an agent based modelling approach in which the growth of each plant is described via our system of ODEs. The model is formulated for the African drought tolerant legume bambara groundnut (Vigna subterranea), which is currently being investigated as a food source in light of climate change and food insecurity challenges. Our model allows us to account for plant diversity and also investigate the effect of individual plant traits (e.g. plant canopy size and planting distance) on the yield of the overall crop. Informed with greenhouse data, model results show that plant positioning relative to other plants has a large impact on individual plant yield. Variation in physiological plant traits from genetic diversity and the environmental effects lead to experimentally observed variations in crop yield. These traits include plant height, plant carrying capacity, leaf accumulation rate and canopy spread. Of these traits plant height and ground cover growth rates are found to have the greatest impact on crop yield. We also consider a range of different planting arrangements (uniform grid, staggered grid, circular rings and random allocation) and find that the staggered grid leads to the greatest crop yield (6% more compared to uniform grid). Whilst formulated specifically for bambara groundnut, the generic formulation of our model means that with changes to certain parameter's, it may be extended to other crop species that form a canopy.


Assuntos
Fabaceae , Vigna , Vigna/genética , Fabaceae/genética , Modelos Teóricos , Produtos Agrícolas , Crescimento e Desenvolvimento
6.
J. Health Biol. Sci. (Online) ; 10(1): 1-9, 01/jan./2022. tab
Artigo em Português | LILACS | ID: biblio-1411663

RESUMO

Objetivo: analisar as habilidades e as práticas de profissionais de saúde da Estratégia Saúde da Família e demais áreas, educação e serviço social em municípios do nordeste brasileiro (Rio Grande do Norte, Maranhão e Piauí), precedente à formação acerca da utilização da Caderneta da Criança. Métodos: Estudo transversal que faz parte de um projeto de Formação de profissionais para o uso da Caderneta da Criança. A população do estudo foi constituída de 140 profissionais que atuam na atenção à criança, em saúde, educação e assistência social. O instrumento de coleta de dados foi formulário Google Forms, com questionário estruturado com 55 questões. A pesquisa tem Parecer Nº3554302. Resultados: observa-se que 15,71% avaliam como ruim a capacidade de conhecê-la de forma minuciosa, e apenas 45% e 3,57% como bom e excelente. Quarenta e seis por cento (46,43%) dos profissionais consideram que utilizam muito a caderneta em sua rotina, porém 24,29% dizem que não a utilizam. Apenas 0,71% sempre preenche a CC com dados relativos à aferição da pressão arterial das crianças e 6,45% sempre registram na CC as intercorrências relativas às doenças, os relatórios de internações, acidentes, as alergias e outros agravos da criança. Conclusões: o estudo aponta ser necessário que haja uma formação de profissionais das unidades de saúde, utilizando metodologias mais criativas, de forma alusiva acerca da necessidade de compreensão da CC como um documento de cidadania, com registros de todas as etapas de crescimento e desenvolvimento da criança, além do acompanhamento da vigilância das vacinas administradas.


Objective: to analyze the skills and practices of health professionals of the Family Health Strategy and other areas, education, and social service in municipalities of northeastern Brazil (Rio Grande do Norte, Maranhão, and Piauí), preceding the training on the use of the Child's Handbook. Methods: cross-sectional study that is part of a project for training professionals to use the Child's Handbook. The study population consisted of 140 professionals working in child care, health, education, and social. The data collection instrument was Google Forms form, with a structured questionnaire with 55 questions. Results: it is observed that 15.71% evaluate as bad the ability to know it thoroughly, and only 45% and 3.57% as good and excellent. Forty-six percent (46.43%) of professionals consider that they use the handbook a lot in their routine, but 24.29% say they do not use it. Only 0.71% always fill out the handbook with data related to the measurement of children's blood pressure and 6.45% always record in the handbook the complications related to diseases, reports of hospitalizations, accidents, allergies, and other injuries of the child. Conclusions: the study points to the need for training of professionals in health units, using more creative methodologies, alluding to the need to understand the child handbook as a citizenship document, with records of all stages of growth and development of the child, in addition to monitoring the surveillance of administered vaccines.


Assuntos
Desenvolvimento Infantil , Saúde da Criança , Estratégias de Saúde Nacionais , Vacinas , Cuidado da Criança , Estudo de Avaliação , Crescimento e Desenvolvimento , Capacitação Profissional
7.
Med. leg. Costa Rica ; 39(2)dic. 2022.
Artigo em Inglês | LILACS-Express | LILACS, SaludCR | ID: biblio-1405587

RESUMO

Abstract Introduction: Adolescent idiopathic scoliosis (AIS) is the most common and severe spinal deformity, which affects children and adolescents in the stage of neuromotor development and skeletal maturity of the sagittal curvatures of the spine. The literature presents several radiation-free instruments to assess and monitor the progression of scoliotic curvature angles in the AIS. However, the reliability and validity of the inclinometer at different stages of growth in relation to X-ray parameters has not been understood to date. Objective: To evaluate the reliability of the inclinometer and its validity with the X-ray exam on the sagittal parameters of the spine in the early and late growth stages of adolescents with AIS. Methods: A cross-sectional study was conducted with 39 adolescents with AIS who were divided into two groups: the initial growth phase (10-13 years) and the late growth phase (14-18 years). The evaluated sagittal parameters of the spine were the angle of the thoracic kyphosis and the angle of the lumbar lordosis, both measured by the X-ray image examination and the inclinometer. Results: The inclinometer showed excellent inter- and intra-examiner reliability for the different growth phases, early and late, with a strong association with the X-ray (gold standard; r = 0.84; p = 0.308 and r = 0.75; p = 0.517). The angle of lumbar lordosis was different between the inclinometer and X-ray instruments in the early and late stages of growth (p < 0.001), with moderate reliability and a less significant correlation with the gold standard of radiography (r = 0.38; p = 0.001 and r = 0.49; p = 0.024). Conclusion: The inclinometer showed excellent reliability and validity for the sagittal parameter of thoracic kyphosis in the early and late stages of growth. The angle of lumbar lordosis measured by inclinometer proved to be of moderate reliability and weak validity when considering the phases of skeletal growth, showing it to be an inefficient instrument for monitoring the lumbar scoliotic curvature for AIS.


Resumen Introducción: La escoliosis idiopática del adolescente (EIA) es la deformidad espinal más común y severa, que afecta a niños y adolescentes en la etapa de desarrollo neuromotor y madurez esquelética de las curvaturas sagitales de la columna. La literatura presenta varios instrumentos libres de radiación para evaluar y monitorear la progresión de los ángulos de curvatura escolióticos en el AIS. Sin embargo, hasta la fecha no se ha entendido la fiabilidad y validez del inclinómetro en diferentes etapas de crecimiento en relación con los parámetros de rayos X. Objectivo: Evaluar la confiabilidad del inclinómetro y su validez con el examen de rayos X sobre los parámetros sagitales de la columna vertebral en las etapas de crecimiento temprano y tardío de adolescentes con EIA. Materiales y métodos: Se realizó un estudio transversal con 39 adolescentes con EIA que se dividieron en dos grupos: la fase de crecimiento inicial (10-13 años) y la fase de crecimiento tardío (14-18 años). Los parámetros sagitales de la columna evaluados fueron el ángulo de la cifosis torácica y el ángulo de la lordosis lumbar, ambos medidos por el examen de imagen de rayos X y el inclinómetro. Resultados: El inclinómetro mostró una excelente confiabilidad inter e intraexaminador para las diferentes fases de crecimiento, temprana y tardía, con una fuerte asociación con la radiografía (estándar de oro; r = 0.84; p = 0.308 y r = 0.75; p = 0,517). El ángulo de lordosis lumbar fue diferente entre el inclinómetro y los instrumentos de rayos X en las etapas tempranas y tardías del crecimiento (p < 0,001), con confiabilidad moderada y una correlación menos significativa con el estándar de oro de la radiografía (r = 0,38; p = 0,001 y r = 0,49; p = 0,024). Conclusión: El inclinómetro mostró excelente confiabilidad y validez para el parámetro sagital de cifosis torácica en etapas tempranas y tardías de crecimiento. El ángulo de lordosis lumbar medido por inclinómetro demostró ser de confiabilidad moderada y validez débil al considerar las fases de crecimiento esquelético, mostrándose como un instrumento ineficiente para monitorear la curvatura escoliótica lumbar para EIA.


Assuntos
Humanos , Adolescente , Adulto , Escoliose/diagnóstico , Raios X , Crescimento e Desenvolvimento
8.
Int J Mol Sci ; 23(23)2022 Dec 05.
Artigo em Inglês | MEDLINE | ID: mdl-36499652

RESUMO

Phytochrome-interacting factors (PIFs) are transcription factors with the basic helix-loop-helix (bHLH) domain. As integration factors between different signal pathways, members of the PIF protein family regulate many aspects of plant growth and development, such as seed germination, photomorphogenesis, thermomorphogenesis, rhythm regulation, flowering response, stomatal development, and stress responses. Our previous studies have shown that the BpSPL2 gene may regulate plants' adventitious root development through PIF genes. Within the Betula platyphylla genome, we identified eight PIF (BpPIFs) genes. We analysed and named them based on a phylogenetic tree, gene structures, and conserved motifs. Synteny analysis indicated that transposition or segmental duplication events played a minor role in the expansion of BpPIFs. The comparative syntenic analysis combined with phylogenetic analysis provided a deep insight into the phylogenetic relationships of BpPIF genes, suggesting that BpPIF proteins are closer to PtPIF than to AtPIF. The analysis of cis-acting elements in promoter regions of BpPIF genes indicated that various elements were related to light, abiotic stress, and plant hormone responsiveness. In addition, we found that these promoters have the transcription factor of B. platyphylla SPL2 (BpSPL2) binding motif GTAC. Expression analysis demonstrated that BpPIF genes, especially BpPIF4, BpPIF9b, and BpPIF10, might be the potential target genes of BpSPL2 in the process of adventitious root formation. Besides providing a comprehensive understanding of the BpPIF family, we propose a hypothetical gene network regulatory model for adventitious root formation.


Assuntos
Fatores de Transcrição Hélice-Alça-Hélice Básicos , Regulação da Expressão Gênica de Plantas , Fatores de Transcrição Hélice-Alça-Hélice Básicos/genética , Fatores de Transcrição Hélice-Alça-Hélice Básicos/metabolismo , Filogenia , Fatores de Transcrição/genética , Fatores de Transcrição/metabolismo , Crescimento e Desenvolvimento , Proteínas de Plantas/genética , Proteínas de Plantas/metabolismo
9.
Sci Rep ; 12(1): 22344, 2022 12 26.
Artigo em Inglês | MEDLINE | ID: mdl-36572702

RESUMO

There are concerns that groundwater use for irrigation and for urban water supply is unsustainable in some parts of Bangladesh, particularly in the agriculturally productive northwest region. We use an integrated population - GDP - food - water model to examine water demand to 2100 in Bangladesh in development scenarios relevant to food and water security. The results indicate that irrigation water demand is projected to increase in coming decades, but later in the century it may decrease due to increasing crop yields and a falling population. The increased demand is greatest in the northwest region and, if unchecked, would increase concerns there about the unsustainable use of groundwater. The growth in demand is determined particularly by growth in crop yields, population growth and the fraction of food demand satisfied by imports. An extreme hot-dry climate change scenario has a lesser impact. This suggests that, in principle, Bangladesh can offset the impacts of climate change on irrigation water demand through its domestic policies. Urban water use currently also leads to concerns over unsustainable groundwater use. Our results suggest that urban water demand is likely to grow proportionately significantly more than irrigation water demand. Alternative sources for urban water are therefore urgently required.


Assuntos
Mudança Climática , Crescimento Demográfico , Bangladesh , Água , Modelos Teóricos , Abastecimento de Água , Crescimento e Desenvolvimento
10.
PLoS One ; 17(11): e0277284, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36374931

RESUMO

Numerous single gene mutations identified in humans and mice result in nail deformities with many similarities between the species. A spontaneous, autosomal, recessive mutation called witch nails (whnl) is described here where the distal nail matrix and nail bed undergo degenerative changes resulting in formation of an abnormal nail plate causing mice to develop long, curved nails. This mutation arose spontaneously in a colony of MRL/MpJ-Faslpr/J at The Jackson Laboratory. Homozygous mutant mice are recognizable by 8 weeks of age by their long, curved nails. The whnl mutation, mapped on Chromosome 15, is due to a 7-bp insertion identified in the 3' region of exon 9 in the Krt90 gene (formerly Riken cDNA 4732456N10Rik), and is predicted to result in a frameshift that changes serine 476 to arginine and subsequently introduces 36 novel amino acids into the protein before a premature stop codon (p. Ser476ArgfsTer36). By immunohistochemistry the normal KRT90 protein is expressed in the nail matrix and nail bed in control mice where lesions are located in mutant mice. Immunoreactivity toward equine KRT124, the ortholog of mouse KRT90, is restricted to the hoof lamellae (equine hoof wall and lamellae are homologous to the mouse nail plate and nail bed) and the mouse nail bed. Equine laminitis lesions are similar to those observed in this mutant mouse suggesting that the latter may be a useful model for hoof and nail diseases. This first spontaneous mouse mutation affecting the novel Krt90 gene provides new insight into the normal regulation of the molecular pathways of nail development.


Assuntos
Doenças da Unha , Unhas Malformadas , Animais , Camundongos , Crescimento e Desenvolvimento , Cavalos , Mutação , Doenças da Unha/genética , Unhas/química , Unhas Malformadas/genética
11.
Int J Mol Sci ; 23(19)2022 Sep 27.
Artigo em Inglês | MEDLINE | ID: mdl-36232696

RESUMO

The NMDA receptor is a Ca2+-permeant glutamate receptor which plays key roles in health and disease. Canonical NMDARs contain two GluN2 subunits, of which 2A and 2B are predominant in the forebrain. Moreover, the relative contribution of 2A vs. 2B is controlled both developmentally and in an activity-dependent manner. The GluN2 subtype influences the biophysical properties of the receptor through difference in their N-terminal extracellular domain and transmembrane regions, but they also have large cytoplasmic Carboxyl (C)-terminal domains (CTDs) which have diverged substantially during evolution. While the CTD identity does not influence NMDAR subunit specific channel properties, it determines the nature of CTD-associated signalling molecules and has been implicated in mediating the control of subunit composition (2A vs. 2B) at the synapse. Historically, much of the research into the differential function of GluN2 CTDs has been conducted in vitro by over-expressing mutant subunits, but more recently, the generation of knock-in (KI) mouse models have allowed CTD function to be probed in vivo and in ex vivo systems without heterologous expression of GluN2 mutants. In some instances, findings involving KI mice have been in disagreement with models that were proposed based on earlier approaches. This review will examine the current research with the aim of addressing these controversies and how methodology may contribute to differences between studies. We will also discuss the outstanding questions regarding the role of GluN2 CTD sequences in regulating NMDAR subunit composition, as well as their relevance to neurodegenerative disease and neurodevelopmental disorders.


Assuntos
Doenças Neurodegenerativas , Transtornos do Neurodesenvolvimento , Receptores de N-Metil-D-Aspartato , Animais , Modelos Animais de Doenças , Crescimento e Desenvolvimento/genética , Crescimento e Desenvolvimento/fisiologia , Camundongos , Doenças Neurodegenerativas/genética , Doenças Neurodegenerativas/metabolismo , Doenças Neurodegenerativas/fisiopatologia , Transtornos do Neurodesenvolvimento/genética , Transtornos do Neurodesenvolvimento/metabolismo , Transtornos do Neurodesenvolvimento/fisiopatologia , Subunidades Proteicas/genética , Subunidades Proteicas/metabolismo , Receptores de N-Metil-D-Aspartato/genética , Receptores de N-Metil-D-Aspartato/metabolismo , Transdução de Sinais , Sinapses/genética , Sinapses/metabolismo , Sinapses/fisiologia
12.
Front Public Health ; 10: 887288, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36311610

RESUMO

Indonesia's health care system relies on non-health professionals called cadres to operate child health promotion programs in the Public Health Center (Puskesmas). Despite this effort, the child malnutrition rate remains high. This study aimed to identify and develop health promotion media that can assist health cadres in promoting child health. This study was divided into three-phase. The first phase was the need assessment using focus group discussion and knowledge, attitude, and practice (KAP); the second phase is video development, which involves medical students, general practitioners, pediatricians, and health promotion experts; and the third phase was video viewing by cadres and post-viewing tests for health cadres. A comparison of pre-test and post-test participants' total scores was performed with the student's T-test. Need assessment showed that the knowledge of the cadres needs improvement and there was a need for proper educational media material that can be used by the Puskesmas. Five videos were produced, four videos were about children's nutritional intake recommendations during four different age groups and one video was about the information and invitation to come to Integrated Health Service Post (Posyandu). There was a significant improvement from pre-test total scores to post-test total scores (p < 0.001). Smartphone application-based educational videos are effective and reliable child health promotion media for Puskesmas staff and parents.


Assuntos
Smartphone , Estudantes de Medicina , Criança , Humanos , Família , Promoção da Saúde , Crescimento e Desenvolvimento
13.
Zhonghua Yu Fang Yi Xue Za Zhi ; 56(9): 1211-1217, 2022 Sep 06.
Artigo em Chinês | MEDLINE | ID: mdl-36207882

RESUMO

With the rapid dissemination of information in modern society, Chinese residents pay more attention to the scientific concept of childcare, which makes the child prevention and health care industry develop rapidly. The law of children's growth and development is extremely complex, so it is necessary to detect different biomarkers according to different growth and development evaluation angles. Human growth hormone(hGH), insulin-like growth factor-1(IGF-1), insulin-like growth factor binding protein-3(IGFBP-3), thyroid hormone, sex hormone, anti-müllerian hormone(AMH) and 25-hydroxy vitamin D(25-OH VD) are common biomarkers to monitor children's growth and development. This article aims to explain the concept and characteristics of common biomarkers of growth and development, summarize the detection methods of common biomarkers of growth and development evaluation developed in recent years, and provide a reference for children's prevention and health care to select appropriate detection biomarkers.


Assuntos
Hormônio do Crescimento Humano , Proteína 3 de Ligação a Fator de Crescimento Semelhante à Insulina , Hormônio Antimülleriano/metabolismo , Biomarcadores , Criança , Crescimento e Desenvolvimento , Hormônio do Crescimento Humano/metabolismo , Humanos , Fator de Crescimento Insulin-Like I/metabolismo , Hormônios Tireóideos , Vitamina D
14.
Zhonghua Yu Fang Yi Xue Za Zhi ; 56(9): 1226-1231, 2022 Sep 06.
Artigo em Chinês | MEDLINE | ID: mdl-36207884

RESUMO

The incidence of children's growth and development diseases such as rickets, obesity, dwarfism and precocious puberty has increased year by year recently. The occurrence and development of these diseases are often closely related to children's malnutrition and endocrine disorders. Plenty of studies have indicated that bone is not only the structural scaffold of human body, but also an important endocrine and hormone target organ. As a series of substances closely related to bone formation and bone resorption, the levels of bone metabolic markers have been confirmed to change in the course of many children's growth and development diseases. The characteristics, classification and application of bone metabolism markers in children's growth and development related diseases was summarized and commented in this article in order to provide reference for the prevention, early diagnosis and treatment effect monitoring of children's growth and development diseases.


Assuntos
Puberdade Precoce , Criança , Crescimento e Desenvolvimento , Hormônios , Humanos , Obesidade/epidemiologia
15.
Enferm. glob ; 21(68): 638-653, Oct. 2022. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-210019

RESUMO

Introducción: El cáncer pediátrico provoca un cambio radical en el entorno externo e interno del niño o adolescente afectando su desarrollo y crecimiento. Objetivo: Sintetizar los hallazgos de estudios de Enfermería que publicaron resultados en la salud física, psicológica, social e inmunitaria mediante el uso de estrategias de distracción para el cuidado. Metodología: Revisión integrativa de literatura, cualitativa de alcance descriptivo y retrospectivo fundamentada en parámetros establecidos por Whittemore y Knafl con cinco etapas. Criterios de inclusión: artículos científicos con resultados en salud física, psicológica, social e inmunitaria mediante uso de la distracción desde enfermería a población pediátrica con diagnóstico oncológico, publicados en 15 bases de datos científicas, idiomas: inglés, portugués y español, entre los años 2011-2020, con nivel de evidencia según Lobiondo Nivel I, II y III, estudios con asignación al azar, con grupo control independiente y separado, basados en evaluación critica del Instituto Joanna Briggs. Resultados: Las estrategias de distracción usadas en niños y adolescentes con diagnóstico oncológico incluyeron: ejercicio, juego, masaje, música y terapias complementarias realizadas en diferentes escenarios que obtuvieron resultados significativos en la salud física, psicológica, social e inmunitaria. Conclusiones: Con el uso de la distracción en el ámbito hospitalario o no hospitalario se logran beneficios en la salud demostrando ser intervención innovadora e importante para el cuidado de enfermería en población pediátrica oncológica. (AU)


Introduction: Pediatric cancer causes a radical change in the external and internal environment of the child or adolescent affecting their development and growth. Objective: To synthesize the findings of nursing studies that published results in physical, psychological, social and immune health through the use of distraction strategies for care. Methodology: Integrative literature review, qualitative descriptive and retrospective based on parameters established by Whittemore and Knafl with five stages. Inclusion criteria: scientific articles with results in physical, psychological, social and immune health through the use of distraction from nursing to pediatric population with oncological diagnosis, published in 15 scientific databases, languages: English, Portuguese and Spanish, between the years 2011-2020, with level of evidence according to Lobiondo Level I, II and III, randomized studies, with independent and separate control group, based on critical evaluation of the Joanna Briggs Institute. Results: The distraction strategies used in children and adolescents with oncological diagnosis included: exercise, play, massage, music and complementary therapies performed in different scenarios that obtained significant results in physical, psychological, social and immune health.Conclusions: With the use of distraction in the hospital or non-hospital setting, health benefits are achieved, proving to be an innovative and important intervention for nursing care in the pediatric oncological population. (AU)


Assuntos
Humanos , Pré-Escolar , Criança , Adolescente , História do Século XXI , Neoplasias , Cuidado da Criança , Enfermagem , Enfermagem Oncológica , Crescimento e Desenvolvimento
16.
Genes (Basel) ; 13(9)2022 09 02.
Artigo em Inglês | MEDLINE | ID: mdl-36140742

RESUMO

To explore the effect of MYOZ1 in the muscle growth and development of meat ducks, MYOZ1 single-nucleotide polymorphism loci were screened at the DNA level in the meat duck population with highest and lowest feed conversion rates. The expression of MYOZ1 was detected using reverse-transcription quantitative polymerase chain reaction. The protein expression of MYOZ1 was detected using Western blotting at the protein level. The results showed that there was a base mutation site at 30 bp and 158 bp in the fourth exon of MYOZ1, which was mutated from C to T (exon4 C30T) and from G to A (exon4 G158A), respectively. The allele frequency of the locus was significantly different between the high and low feed conversion rate groups (p < 0.01). The relative expression of MYOZ1 mRNA in breast muscle tissue of HF ducks was significantly higher than that of LF ducks (p < 0.01). The MYOZ1 protein expression of HF ducks was significantly higher than that of LF ducks (p < 0.01). In general, MYOZ1 has a positive regulatory effect on the muscle growth and development of meat ducks. The results of this study lay a certain theoretical basis for the muscle growth and development of meat ducks.


Assuntos
Patos , Carne , Animais , Patos/genética , Crescimento e Desenvolvimento , Carne/análise , Músculo Esquelético , RNA Mensageiro
17.
Int J Mol Sci ; 23(18)2022 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-36142203

RESUMO

Temperature is an important environmental factor affecting the growth and development of silkworm (Bombyx mori). To analyze the effect of intestinal microbes on silkworm in response to a high-temperature environment, this study used a combination of high throughput sequencing and biochemical assays to detect silkworm intestinal microbes treated with high temperature for 72 h. The results show that high temperature affects the intestinal microbes of silkworm and that there are sex differences, specifically, females were more sensitive. The changes in the metabolism and transport ability of silkworm intestinal tissues under high temperature are related to the intestinal microbes. High temperatures may affect the intestinal microbes of silkworms, regulating the activity of related digestive enzymes and substance transport in the intestine, thereby affecting the silkworm's digestion and absorption of nutrients, and ultimately affecting growth and development.


Assuntos
Bombyx , Animais , Bombyx/química , Feminino , Crescimento e Desenvolvimento , Intestinos , Larva , Masculino , Temperatura
18.
Comput Math Methods Med ; 2022: 5096406, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36081428

RESUMO

Adenoid hypertrophy (AH) is a common disease in otorhinolaryngology. Children with chronic snoring and hypoxia are susceptible to long-term nasal obstruction, while long-term open-mouth breathing may cause craniofacial bone development disorders and dull facial expressions, the so-called adenoid face. The purpose of this work is to analyze the influence of AH-induced airway obstruction (AO) on the growth and development of craniomaxillofacial structure and respiratory function (RF) in children. The clinical data of 56 AH children (observation group) and 42 healthy children with physical examination (control group) who visited the Hebei Eye Hospital during the same period were retrospectively analyzed. All children received acoustic rhinometry and X-ray cephalometric measurements. The upper airway structure, sleep disorder score, and A/N value of nasopharyngeal lateral X-ray images were compared between cases and controls. For AH children, sleep tests were also performed to assess their RF. X-ray cephalometric measurements of facial morphology showed obvious vertical growth, mandibular retrognathia, and enlarged mandibular angle in AH children. AH mainly affects the size of the nasopharyngeal and oropharyngeal airway. AH children presented with higher nasal airway resistance (5.11 ± 1.95 cmH2O/L min) and lower nasopharyngeal volume (NPV) (16.86 ± 3.93 cm3) than controls. Of the AH children, 45 had abnormal RF, including 4 with obstructive sleep apnea syndrome. The A/N value of nasopharyngeal lateral X-ray images was significantly higher in AH children than in controls. Besides, worse sleep quality was found in AH children. The above differences were all of statistical significance. The above indicates that AH can affect the size of the nasopharyngeal and oropharyngeal airway, change children's respiratory mode and RF, increase nasal resistance, and decrease NPV, resulting in upper respiratory tract stenosis, as well as craniomaxillofacial and oral malformations, which affects children's normal growth and development.


Assuntos
Tonsila Faríngea , Obstrução das Vias Respiratórias , Tonsila Faríngea/diagnóstico por imagem , Obstrução das Vias Respiratórias/diagnóstico por imagem , Obstrução das Vias Respiratórias/etiologia , Criança , Crescimento e Desenvolvimento , Humanos , Hipertrofia , Estudos Retrospectivos
19.
J Food Sci ; 87(10): 4429-4439, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-36102046

RESUMO

Cape gooseberry fruits are increasingly recognized due to their excellent organoleptic and functional characteristics as a food. As the cultivation of this fruit expands, it is necessary to determine the quality characteristics and evolution of the new growing zones. This study sought to characterize the growth and development of cape gooseberry fruits, Ecotype Colombia, in the Ventaquemada region (Department of Boyacá in Colombia). For the experiments, 50 plants were taken completely at random from which 20 flowers of the middle third were selected and marked considering that 50% of the flowers were open. The selected cape gooseberry plants were 9 months old from the establishment. Samples were carried out every 5-7 days to evaluate changes in different physiological and physicochemical properties of the fruits such as equatorial diameter, weight, dry matter, respiration intensity (RI), total soluble solids (SST), titratable acidity (TA), and maturity ratio (SST/TA). Logistic and modified enzyme kinetics models were fitted to represent the change in these characteristics as a function of growth time and to establish a suitable maturity index. A rapid increase in the growth and a substantive change in the properties of the fruits were observed between 36 and 45 days after anthesis (DAA) and stabilization between 60 and 65 DAA, which constitutes the stage of physiological maturity. At this stage, fruits with a polar/equatorial diameter of 2.2-2.5 cm, 14.9% TSS, 2.2% TA, and 191.7 cm3 CO2 /g/d RI were obtained. Likewise, from the adjusted models, it was possible to identify these changes, especially for the relative growth rate (RGR), color index, and maturity ratio. PRACTICAL APPLICATION: In this work, we present the characterization of some physicochemical properties of cape gooseberry throughout its development and preharvest growth. This fruit is of wide interest due to its broad nutritional properties and is known as a "superfruit." The monitoring of the changes in the quality characteristics is important because it allows producers to define an optimum maturity stage for its commercialization. We also fit suitable regression models to relate the evolution in the product as a function of time and provide prediction tools to monitor fruit development. The above can help growers better schedule their production cycles.


Assuntos
Physalis , Ribes , Frutas/química , Ecótipo , Colômbia , Antivirais/análise , Dióxido de Carbono/análise , Crescimento e Desenvolvimento
20.
Ecotoxicol Environ Saf ; 244: 114029, 2022 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-36055045

RESUMO

Cadmium (Cd) is ubiquitous in our environment and can easily bioaccumulate into the organism after passage through the respiratory and digestive tracts. Long-term exposure to Cd can result in the significant bioaccumulation in organism because of its long biological high-life (10-30 years), which exerts irreversible damages on the health of animals and humans. Although there are increased evidence of impeding the normal function of female reproduction resulted from Cd exposure, the mechanism of the negative action of Cd on the growth and development of ovarian follicle remains enigmatic. Thus, the purpose of the presented study is to summarize available literature which describing Cd-related toxicity involved in the adverse effects on the growth and development of the ovarian follicle. In conclusion, it is suggested that Cd causes damage to the folliculogenesis of mammalians, which results in the decline in the number and quality of ovulated oocytes and the failure in the fertilization. The mechanism behinds that may be linked to the interference to the production of reproductive hormones and the augment of reactive oxygen species (ROS). Furthermore, the enhanced ROS, in turn, impairs various molecules including proteins, lipids and DNA, as well as the balance of the antioxidant defense system, mitochondrial homeostasis, endoplasmic reticulum, autophagy and epigenetic modification. This review is expected to elaborate the toxic mechanism of Cd exposure to the growth and development of ovarian follicles and provide essential remediation strategies to alleviate the damage of Cd to female reproductive health.


Assuntos
Intoxicação por Cádmio , Cádmio , Animais , Antioxidantes , Cádmio/toxicidade , Feminino , Crescimento e Desenvolvimento , Hormônios , Humanos , Lipídeos , Mamíferos/metabolismo , Folículo Ovariano , Espécies Reativas de Oxigênio/metabolismo , Reprodução
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