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2.
Comput Intell Neurosci ; 2022: 9949875, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36199954

RESUMO

Objective: To improve the level of clinical diagnosis and treatment, reduce the incidence of complications, and provide the basis for clinicians to choose an appropriate treatment, this research explores the removal methods of the impacted denture in the esophagus by endoscopy. Methods: Based on the clinical information, treatment methods and complications of 72 patients with denture impaction in the esophagus admitted to our hospital from January 2016 to March 2021, which were divided into the group treated with painless endoscopy and the group treated with conventional endoscopy, retrospective analysis of the therapeutic effect and complications was conducted. Results: There was no statistically significant difference between the two groups in terms of denture removal rate (P > 0.05). There were statistically significant differences between the two groups in terms of operating time and incidence rates of complications during and after the procedure. The operating time of the group treated with painless endoscopy was significantly shorter than the group treated with conventional endoscopy (P < 0.05). The incidence rates of complications during and after the procedure of the group treated with painless endoscopy were significantly lower than the group treated with conventional endoscopy (P < 0.05). Conclusions: Compared with the conventional endoscopy, painless endoscopic management of denture impaction in the esophagus under general anesthesia with tracheal intubation improves the clinical efficacy and reduces the adverse reactions. Thus, it is worthy of clinical popularization and application.


Assuntos
Corpos Estranhos , Dentaduras/efeitos adversos , Endoscopia , Esôfago , Corpos Estranhos/complicações , Corpos Estranhos/diagnóstico , Humanos , Estudos Retrospectivos
3.
Shanghai Kou Qiang Yi Xue ; 31(3): 313-317, 2022 Jun.
Artigo em Chinês | MEDLINE | ID: mdl-36204964

RESUMO

PURPOSE: To analyze the clinical effect of digital impression combined with all-ceramic denture restoration on patients with dental defects. METHODS: A study was conducted on 120 patients with dental defects admitted to Dongfeng Stomatological Hospital from June 2018 to June 2020. The two groups of patients were randomly divided into digital imprinting modules and silicone rubber imprinting modules using a random number table method. There were 60 cases in each group. The silicone rubber imprint module used traditional silicone impression combined with all-ceramic denture restoration, while the digital imprint module used digital impression combined with all-ceramic denture restoration.The clinical efficacy of the two groups was observed. Gingival index (GI), periodontal index (PI) before dental restoration, during dental restoration and 6 monthes after dental restoration were compared. The adjacent surface contact conditions, occlusion and adverse reactions of the two groups were compared. SPSS 22.0 software package was used for statistical analysis. RESULTS: The two groups of patients selected grade A and grade B for the evaluation of the restoration when the restoration was completed. The number of patients who chose grade A for the digital imprint module was more than that of the silicone rubber imprint module,but there was no significant difference(P>0.05). Six months after the tooth was worn, GI and PI indexes of the two groups of patients increased. GI and PI indexes of the silicone rubber stamping module were significantly higher than those of the digital stamping module(P<0.05). When dental restoration was completed and 6 months after the tooth was replaced, the pass rate of contact between the adjacent surfaces of the imprinting module patients was significantly higher than that of the silicone rubber imprinting module(P<0.05). When dental restoration was completed, the occlusion of the digital imprinting module patients was significantly better than that of the silicone rubber imprinting module(P<0.05). Six months after wearing the denture, there was no significant difference in occlusion between the two groups of patients(P>0.05). When dental models of the two groups of patients were taken, the incidence of adverse reactions in patients with digital imprints was significantly lower than that of silicone rubber imprints(P<0.05). CONCLUSIONS: The use of digital impressions combined with all-ceramic restorations to repair patients with dental defects can effectively improve the treatment effect, improve prognostic GI and PI indexes of the patients, increase the pass rate of the adjacent surface contact and occlusion of the tooth, and reduce the process of dental restoration. The incidence of adverse reactions are minimal, with good prognostic effects. It is worthy of clinical application.


Assuntos
Coroas , Porcelana Dentária , Cerâmica , Desenho Assistido por Computador , Técnica de Moldagem Odontológica , Planejamento de Prótese Dentária/métodos , Dentaduras , Humanos , Elastômeros de Silicone
4.
Int J Mol Sci ; 23(18)2022 Sep 09.
Artigo em Inglês | MEDLINE | ID: mdl-36142344

RESUMO

Polymers remain an integral part of denture fabrication materials, specifically polymethylmetacrylate (PMMA). PMMA has been extensively used, particularly in construction as a denture base material. Nonetheless, various challenges, including microbial threats in the form of candidiasis occurrence, still remain a biological challenge to denture wearers. The present article comprehensively reviews the biomodifications introduced to denture components, in particular denture base material, to improve the overall biological properties, together with physical, mechanical, structural integrity, and optical properties. In addition, fundamental information specifically to PMMA as a conventional denture base material and the causative aetiological microbial agents for biological threat to dentures are explored.


Assuntos
Polímeros , Polimetil Metacrilato , Bases de Dentadura , Dentaduras , Teste de Materiais , Polímeros/química , Polimetil Metacrilato/química , Propriedades de Superfície
5.
Chin J Dent Res ; 25(3): 215-222, 2022 Sep 14.
Artigo em Inglês | MEDLINE | ID: mdl-36102891

RESUMO

OBJECTIVE: To evaluate the accuracy of 10 intraoral scanners for single-crown and three-unit preparation models. METHODS: A maxillary partially edentulous model was fabricated. A dental cast scanner was used to obtain standard tessellation language (STL) data. Ten intraoral scanners, namely Trios 2 (TR2; 3Shape, Copenhagen, Denmark), True Definition (TD; 3M, Saint Paul, MN, USA), CEREC AC Omnicam (OM; Dentsply Sirona, Charlotte, NC, USA), Organical Scan Oral (OS; R+K, Berlin, Germany), PlanScan (PS; Planmeca, Helsinki, Finland), DWIOP (DW; Dental Wings, Montreal, Canada), Xianlin (XL; Hangzhou Xianlin, Hangzhou, China), DL-100 (DL; Guangzhou Longcheng, Guangzhou, China), Trios 3 (TR3; 3Shape) and i500 (MD; MEDIT, Seoul, South Korea) were used to obtain stereolithography data as test groups. Trueness, precision and surface accuracy were evaluated by deviation analysis using 3D image processing software. One tooth with a three-unit preparation for each test group was registered with the reference scan data, and the absolute distance from another tooth was calculated as the absolute accuracy. The data were analysed using a Mann-Whitney U test and Dunn-Bonferroni test (α = 0.05). RESULTS: The best trueness, precision and surface accuracy of scanning single crown preparation were recorded with TD (trueness 2.9 µm and precision 1.9 µm) and XL (surface accuracy 20.3 ± 2.9 µm). The best trueness, precision, surface accuracy and absolute accuracy of three-unit preparations were recorded with TD (2.6 µm), XL (1.9 µm), OM (27.1 ± 5.2 µm) and TR3 (79.2 ± 19.6 µm), respectively. There was no statistically significant difference in trueness between single- and multiple-unit preparations for any of the intraoral scanners (P > 0.05). A statistically significant difference in the surface accuracy between single and multiple preparations was found for TR2, TD, OM, DW, XL, DL and MD (P < 0.05). CONCLUSION: The trueness and precision of intraoral scanners for scanning three-unit preparations were nearly the same as those for single-crown preparations; however, with the exception of OS, PS and TR3, the surface accuracy of single-crown preparations was significantly better than that for three-unit preparations.


Assuntos
Técnica de Moldagem Odontológica , Dente , Desenho Assistido por Computador , Coroas , Dentaduras
6.
Br Dent J ; 233(2): 70, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-35869188
7.
Artigo em Inglês | MEDLINE | ID: mdl-35886697

RESUMO

OBJECTIVE: A scoping review of available advice to address eating problems experienced by people who wear dentures was conducted in accordance with the PRISMA statement. The objective was to identify and map type, volume, and content of the available eating advice. METHODS: Medline, CINAHL, and grey literature databases and Google were searched. Relevant content pertaining to study type, peer-review vs. grey literature, country of origin, advice content, and methods to evaluate effectiveness was mapped. RESULTS: Of the 4591 records identified from peer-reviewed literature, 56 full papers underwent duplicate screening, resulting in 26 papers (from Germany (n = 1), Europe (n = 1), India (n = 2), Japan (n = 7), UK (n = 6), USA (n = 6), or other (n = 3)) being included in the review. These yielded 18 different items of relevant eating advice. Of the 258 screened websites, 63 were included, yielding 30 different items of eating advice. The most-cited advice was to eat soft food and avoid hard and sticky food, cut food into bite-sized pieces, and chew on both sides of the mouth and chew slowly and thoroughly. The identified advice was not supported by reference to peer-reviewed evidence. Advice included some conflicting messages and some advice was non-compliant with authoritative nutritional advice (e.g., avoid red meat, take a vitamin supplement). CONCLUSION: There is support for providing eating advice at the time of denture provision. A broad range of advice based on clinical experience to support people who wear dentures to overcome the functional limitations exists. However, the efficacy of this advice in improving diet and eating experience has not been tested.


Assuntos
Boca Edêntula , Dentaduras , Dieta , Ingestão de Alimentos , Alimentos , Humanos , Mastigação
8.
J Mech Behav Biomed Mater ; 134: 105363, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-35850038

RESUMO

Ceramic composites based on (Ce, Y)-TZP/Al2O3 system have great potential for applications as dental implants due to their unusually great balance between good mechanical properties and resistance to hydrothermal degradation. Surface roughness plays an important role in controlling these properties, but few studies have investigated the relationship between cytocompatibility and surface roughness, at levels considered moderate and low, comparable to titanium implants. In this work, bending strength, hydrothermal degradation and biological evaluation of a ceramic composite based on (Ce,Y)-TZP/Al2O3 system were investigated as a function of surface roughness. Compacted samples were sintered at 1500 °C - 2h and then submitted to different surface treatments: Group 1 composed of samples with smooth surfaces, Group 2 and Group 3 composed of rough surfaces (grinded with 15 µm or 45 µm diamond sandpaper, respectively. Samples were characterized by X-ray diffraction, scanning electron microscopy, contact angle and optical profilometry and then subjected to hydrothermal degradation tests in autoclave (134 °C - 2 bar) using artificial saliva. The Piston-on-three-balls (P-3B) testing was used to determine flexural strength. To assess indirect cytotoxicity, samples were immersed in the culture medium for NIH-3T3 cells for 72 h. Furthermore, cell adhesion and proliferation were investigated using MG63 cells (human osteosarcoma) after 3, 7, 14, and 21 days of culture. Cytotoxicity, adhesion, and cell proliferation were examined by the Methyl Tetrazolium salt (MTS) and Alizarin Red, using a confocal laser microscope. The results indicated that the materials have high resistance to degradation. Furthermore, the (Ce,Y)-TZP/Al2O3 composites are not cytotoxic. The flexural strength of the composites was 913 ± 103 MPa in samples presenting original (smooth) surface, however, a reduction in the order of 17% was observed in samples containing rough surfaces. The rougher samples show the best cellular adhesion and proliferation, leading to the formation of a mineralized matrix after 21 days. These results clearly suggest that the new (Ce,Y)-TZP/Al2O3 brand is strong and highly biocompatible and warrants further study.


Assuntos
Cerâmica , Zircônio , Animais , Adesão Celular , Materiais Dentários , Dentaduras , Humanos , Teste de Materiais , Camundongos , Microscopia Eletrônica de Varredura , Propriedades de Superfície , Ítrio
9.
Br Dent J ; 233(1): 20-26, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-35804119

RESUMO

Dentures are an excellent treatment modality for partial and edentate patients; however, improper denture care and hygiene can result in both decreased longevity of the prosthesis and increased risk of developing dental caries, periodontal disease and oral candidosis. Previously, it has been shown that patients and dental professionals are unaware of the different materials and methods available for optimum denture care and hygiene. This article provides an overview of the key legislation and main commercially available methods for denture cleanliness and hygiene, and serves as a basis for providing tailored denture hygiene for denture wearers.


Assuntos
Cárie Dentária , Doenças Periodontais , Dentaduras , Humanos , Higiene
10.
Hypertens Res ; 45(10): 1553-1562, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-35869286

RESUMO

The relationship between masticatory performance and hypertension has seldom been studied. The association between hypertension and tooth loss with/without denture use is unclear. This cross-sectional study examined the relationship between hypertension and masticatory performance and whether the relationship between hypertension and the number of teeth varied with denture use among older Japanese adults. Hypertension was defined as a systolic or diastolic blood pressure ≥140 or ≥90 mm Hg, respectively, or the use of antihypertensive medications. Masticatory performance was assessed using a chewable gummy jelly. The number of teeth and denture use were visually assessed by a trained dental hygienist. Poisson regression analyses were carried out to estimate the prevalence ratio and 95% confidence interval (CI) of hypertension with the number of teeth (≥28, 20-27, or 0-19 teeth), quartiles of masticatory performance (Q1: highest [reference] to Q4: lowest), and tooth loss with/without denture use. Hypertension was significantly associated with masticatory performance in participants in Q3 (prevalence ratio = 1.35; 95% CI = 1.07, 1.72) and Q4 (prevalence ratio = 1.31; 95% CI = 1.01, 1.69). There was no association between tooth loss and hypertension. Compared to participants with >28 teeth, the prevalence ratios and 95% CIs of those without dentures and those with 20-27 teeth were 1.33 (95% CI = 1.06, 1.68) and 1.69 (95% CI = 1.21, 2.37), respectively, in those with 0-19 teeth. Masticatory performance was inversely associated with hypertension, and tooth loss without the use of dentures was related to hypertension. Therefore, masticatory function may be important for preventing hypertension among older adults.


Assuntos
Hipertensão , Perda de Dente , Idoso , Estudos Transversais , Dentaduras , Humanos , Hipertensão/complicações , Mastigação/fisiologia , Perda de Dente/complicações , Perda de Dente/epidemiologia
11.
Clin Implant Dent Relat Res ; 24(4): 522-531, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35679127

RESUMO

PURPOSE: This crossover study aimed to evaluate chewing efficiency and maximum bite force (BF) of conventional dentures, fixed prostheses, and milled bar overdentures (MO) used for All-on-4 implant rehabilitation of atrophied mandibular ridges. METHODS: Sixteen edentulous participants with resorbed mandibular ridges received new conventional dentures (CD, control). Four implants were inserted after 3 months in the mandible using the All-on-4 protocol and loaded immediately with acrylic prosthesis. In a crossover manner, each patient had either fixed restoration (FR, 12 occlusal units) or MO (14 occlusal units) randomly in a crossover study design. Chewing efficiency was evaluated using the mixing ability test. The hue deviation (HD) of two-colored gum was calculated after being chewed for 5, 10, 20, 30, and 50 masticatory cycles. Maximum BF was evaluated using a BF device. HD and BF were measured after using CD, FR, and MO prostheses. RESULTS: For all groups, the highest HD (i.e., the lowest chewing efficiency) was noted with 5 strokes, followed by 10, 20, 30 strokes, and the lowest HD (i.e., the highest chewing efficiency) was noted with 50 strokes. For all number of chewing strokes, CD showed the highest HD, then FR, and MO recorded the lowest HD. The highest BF was observed with MO, then FR, and the lowest BF was noted with CD. CONCLUSION: Within the limitations of this short-term investigation, both FR and MO used for All-on-4 implant rehabilitation of patients with resorbed mandibular ridges improve masticatory efficiency and maximum BFs compared to CD. However, MO was associated with significantly higher chewing efficiency and maximum BFs than fixed prosthesis.


Assuntos
Implantes Dentários , Revestimento de Dentadura , Força de Mordida , Estudos Cross-Over , Prótese Dentária Fixada por Implante , Dentaduras , Humanos , Mandíbula/cirurgia , Mastigação , Satisfação do Paciente
12.
Dent Mater J ; 41(5): 741-748, 2022 Oct 02.
Artigo em Inglês | MEDLINE | ID: mdl-35768221

RESUMO

The need for denture adhesives is increasing worldwide, but few denture-care products target denture adhesive users. Foam denture cleaners have been recently marketed to assist brush denture cleaning, but there is a lack of objective evaluation. In this study, we compared the detergency of denture adhesives using six commercial foam-denture cleaners. For removing the adhesives, most of the tested cleaners were effective in immersion experiments, and three cleaners were more effective in the denture cleaning experiment compared to control water. However, only one could effectively remove the slime that is derived from the adhesive and detergency of artificial dirt. The surface roughnesses of the denture base and the relining material revealed that prolonged immersion in some cleaners could be affected. The results suggest that different commercial foam denture cleaners have different detergency levels, and that some cleaners may affect the properties of denture materials upon long-term use.


Assuntos
Cimentos Dentários , Higienizadores de Dentadura , Adesivos , Retenção de Dentadura , Dentaduras , Propriedades de Superfície , Água
13.
Lett Appl Microbiol ; 75(2): 195-209, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35634756

RESUMO

The United Nations suggests the global population of denture wearers (an artificial device that acts as a replacement for teeth) is likely to rise significantly by the year 2050. Dentures become colonized by microbial biofilms, the composition of which is influenced by complex factors such as patient's age and health, and the nature of the denture material. Since colonization (and subsequent biofilm formation) by some micro-organisms can significantly impact the health of the denture wearer, the study of denture microbiology has long been of interest to researchers. The specific local and systemic health risks of denture plaque are different from those of dental plaque, particularly with respect to the presence of the opportunist pathogen Candida albicans and various other nonoral opportunists. Here, we reflect on advancements in our understanding of the relationship between micro-organisms, dentures, and the host, and highlight how our growing knowledge of the microbiome, biofilms, and novel antimicrobial technologies may better inform diagnosis, treatment, and prevention of denture-associated infections, thereby enhancing the quality and longevity of denture wearers.


Assuntos
Anti-Infecciosos , Microbiota , Biofilmes , Candida albicans , Dentaduras/microbiologia , Humanos
14.
JNMA J Nepal Med Assoc ; 60(248): 410-412, 2022 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-35633218

RESUMO

Clinical findings of foreign body aspiration, generally, are subtle. Scrutinous clinical suspicion is always recommended. Here, we present a rare case of an adult male, who under the influence of alcohol had aspirated a row of his artificial denture without his conscience of where his denture got missing and presented to our outpatient department with non-specific symptoms. With clinical examination and advanced diagnostics, he was successfully managed with rigid bronchoscopy. With the advancement in diagnostic techniques and our widened knowledge of the condition, utmost early detection has been possible and our case report reinforces the need for a low threshold for foreign body aspiration suspicion, especially in adults with dentures, and the use of rigid bronchoscopy as a plausible tool for the prompt management of the aspiration. Keywords: bronchoscopy; case reports; dentures; foreign bodies.


Assuntos
Broncoscopia , Corpos Estranhos , Adulto , Afeto , Dentaduras/efeitos adversos , Corpos Estranhos/diagnóstico , Corpos Estranhos/cirurgia , Humanos , Masculino , Pacientes Ambulatoriais
15.
Pol Merkur Lekarski ; 50(296): 114-117, 2022 Apr 19.
Artigo em Inglês | MEDLINE | ID: mdl-35436274

RESUMO

The issue of reuse of metal alloys in dentistry raises debatable questions about their impact on the human body. AIM: The aim of the study was the evaluation of the biocompatibility of metal structures of dentures made from cobalt-chromium and nickelchromium alloys Remanium GM 700 and Remanium CSe after repeated vacuum remelting. MATERIALS AND METHODS: Clinical study and treatment with fixed prostheses based on Remanium GM 700 and Remanium CSe were performed among 120 patients aged 25-60 years. The biocompatibility of the above-mentioned denture designs with oral tissues was studied. RESULTS: Prostheses made from Remanium GM 700 and Remanium CSe alloys are biologically indifferent, which is confirmed by the indicators of alkaline and acid phosphatase activity within the physiological norm. Regardless of the number of remelts, these alloys do not cause dysbacteriosis. The obtained results do not depend on the terms of observation, which indicates the safe use of remolten alloys for dental prosthetics. CONCLUSIONS: The investigated alloys are biocompatible and can be used for the manufacture of solid structures of dentures.


Assuntos
Ligas de Cromo , Cobalto , Ligas de Cromo/química , Dentaduras , Humanos , Teste de Materiais
16.
Photodiagnosis Photodyn Ther ; 39: 102874, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35470125

RESUMO

AIM: The present study aimed to evaluate the anticandidal effectiveness of PDT, DL, Triphala, CHX, and NE and their effects on Ra and the hardness of polyamide denture base colonized with C. Albicans. MATERIAL AND METHODS: A total of 50 thermo-injected polyamide denture resins were constructed and inoculated by the American Type Culture Collection (ATCC) of C. albicans in an in-vitro setup. The specimens were arbitrarily allocated into five groups, pre-candida count was measured then subjected to the diverse polyamide denture disinfection methodologies: Group 1: PDT, Group 2: Diode Laser, group 3: Triphala, group 4: 0.12% CHX (Control) and group 5 Neem extract. After disinfection protocol, post-candida count (CFU/ml) was assessed. Surface roughness and surface hardness of polyamide dentures were evaluated and statistical differences in the Ra and Vickers hardness was also assessed. Statistical analysis was performed for CFU/mL (log10) for exposed C. albicans by two-way ANOVA and Tukey's multiple test (p>0.05). For normality of the data, Kolmogorov Smirnov test was executed. RESULTS: The highest anti-microbial efficacy against Candida colonies was displayed by chemical control group 0.12% CHX (11.39 ± 1.8 CFU/ml). This was comparable to herbal NE (12.45 ± 2.9 CFU/ml) (p>0.05). There was no statistical difference found in the surface hardness values among the disinfected groups. Group 2: DL (1.32 ± 0.13 µm) showed the highest Ra value comparable to group 1: PDT (1.21 ± 0.22 µm) CONCLUSION: Polyamide denture base colonized with C. Albicans and disinfected with 0.12% Chlorhexidine and Neem extract demonstrated the highest antimicrobial efficacy with decreased surface roughness and no alteration in denture hardness.


Assuntos
Desinfetantes , Fotoquimioterapia , Resinas Acrílicas/farmacologia , Candida , Candida albicans , Higienizadores de Dentadura/farmacologia , Dentaduras , Desinfetantes/farmacologia , Dureza , Teste de Materiais , Nylons/farmacologia , Fotoquimioterapia/métodos , Extratos Vegetais/farmacologia , Propriedades de Superfície
17.
Pol Merkur Lekarski ; 50(295): 13-15, 2022 Feb 22.
Artigo em Inglês | MEDLINE | ID: mdl-35278291

RESUMO

Laser Doppler flowmetry is a simple, atraumatic, safe and reliable method of functional diagnosis, so this method is widely used in almost all medical disciplines that require the study of microcirculation in humans. AIM: The aim of the study was to improve the quality of orthopedic treatment of patients with complete adentia by making removable orthopedic structures according to an improved method and under the control of studying the hemodynamics of the mucous membrane of the prosthetic area. MATERIALS AND METHODS: The study of blood microcirculation in the mucous membrane of the prosthetic area was performed in 20 patients of the comparison group using prostheses made by standard methods and in 20 patients of the study group with prostheses made by advanced methods, before prosthetics and at different times after fixation of constructions: 1 day, 1 month and 1 year. RESULTS: Our results showed that the microcirculation in the control group before prosthesis significantly (p<0,001) differs from the values obtained after 1 year after use, indicating an increase in vascular perfusion. Regarding the main group - the indicators for this parameter did not differ significantly (p>0,05). The study of flaxmotion index revealed perfusion variability in the control group - from 1.09 to 1.39, but this difference is not significant (p>0,05). In the main group the difference is not significant, p>0.05. Analyzing the indicators of intravascular resistance, we saw a significant (p<0,05) difference in the control group between the initial stage of the study and the last, while in patients of the main group the indicators at the same stages did not differ significantly (p>0.05). CONCLUSIONS: Prostheses made by our improved method have a more favorable effect on the capillary circulation of the prosthetic area throughout the period of use of prostheses on the fabric of the prosthetic area.


Assuntos
Dentaduras , Hemodinâmica , Humanos , Microcirculação , Membrana Mucosa
18.
J Prosthodont ; 31(7): e53-e65, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35322481

RESUMO

PURPOSE: To assess the nutritional profile of denture wearers through a retrospective cohort study using nutritional biomarkers from matched electronic dental and health record (EDR-EHR) data. MATERIALS AND METHODS: The case group (denture wearers) included matched EDR-EHR data of patients who received removable partial, complete, and implant-supported prosthodontic treatments between January 1, 2010 and December 31, 2018, study time. The control (nondenture wearers) group did not have recorded denture treatments and included patient records within 1 year of the denture index date (first date of case patients' receiving complete or partial denture) of the matching cases. The qualified patients' EDR were matched with their EHR based on the availability of laboratory reports within 2 years of receiving the dentures (index date). Nutritional biomarkers were selected from laboratory reports for complete blood count, comprehensive and basic metabolic profile, lipid, and thyroid panels. Summary statistics were performed, and general linear mixed effect models were used to evaluate the rate of change over time (slope) of nutritional biomarkers before and after the index date. Likelihood ratio tests were performed to determine the differences between dentures and controls. RESULTS: The final cohort included 10,481 matched EDR-EHR data with 3,519 denture wearers and 6,962 controls that contained laboratory results within the study time. The denture wearers' mean age was 57 ±10 years and the control group was 56 ±10 years with 55% females in both groups. Pre-post analysis among denture wearers revealed decreased serum albumin (p = 0.002), calcium (p = 0.039), creatinine (p < 0.001) during the post-index time. Hemoglobin (Hb) was higher pre-index, and was decreasing during the time period but did not change post-index (p < 0.001). Among denture wearers, completely edentulous patients had a significant decrease in serum albumin, creatinine, blood urea nitrogen (BUN), but increased estimated glomerular filtration rate (eGFR). In partially edentulous patients, total cholesterol decreased (p = 0.018) and TSH (p = 0.004), BUN (p < 0.001) increased post-index. Patients edentulous in either upper or lower arch had decreased BUN and eGFR during post-index. Compared to controls, denture wearers showed decreased serum albumin and protein (p = 0.008), serum calcium (p = 0.001), and controls showed increased Hb (p = 0.035) during post-index. CONCLUSIONS: The study results indicate nutritional biomarker variations among denture wearers suggesting a risk for undernutrition and the potential of using selected nutritional biomarkers to monitor nutritional profile.


Assuntos
Boca Edêntula , Avaliação Nutricional , Idoso , Cálcio , Creatinina , Prótese Total , Dentaduras , Eletrônica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Albumina Sérica
19.
Artigo em Inglês | MEDLINE | ID: mdl-35270743

RESUMO

This study aimed to characterize self-reported headaches because of problems with the teeth, mouth, jaws, or dentures (HATMJD) in chronic patients with temporomandibular disorders (TMDs) in order to compare their results with those of TMD patients without such headaches and to investigate the associations of HATMJD with depression, anxiety, physical symptoms, oral behaviors, and sleep quality. We conducted a case-control study on consecutive chronic TMD patients referred to the University Medical Center of Ljubljana, Slovenia. A self-reported HATMJD was extracted from item #12 in the 49-item version of the Oral Health Impact Profile questionnaire. Axis II instruments of the Diagnostic Criteria for TMD (i.e., for screening of depression, anxiety, specific comorbid functional disorders, and oral behaviors) and the Pittsburgh Sleep Quality Index were used in this study. In total, 177 TMD patients (77.4% women; mean age: 36.3 years) participated in this study; 109 (61.6%) patients were classified as TMD patients with HATMJD. TMD patients with at least mild depressive and anxiety symptoms, with at least low somatic symptom severity, and a high number of parafunctional behaviors had more HATMJD. Parafunctional behavior and sleep quality were the most prominent predictive factors of the occurrence of HATMJD. TMD patients with HATMJD have more psychosocial dysfunction, a higher frequency of oral behaviors, and poorer sleep quality than TMD patients without such headaches.


Assuntos
Transtornos da Articulação Temporomandibular , Adulto , Estudos de Casos e Controles , Dentaduras , Feminino , Cefaleia/complicações , Cefaleia/etiologia , Humanos , Arcada Osseodentária , Masculino , Boca , Transtornos da Articulação Temporomandibular/complicações , Transtornos da Articulação Temporomandibular/epidemiologia
20.
J Oral Sci ; 64(2): 161-166, 2022 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-35321964

RESUMO

PURPOSE: This study was designed to investigate the in vitro effects of geraniol (GE) and thymoquinone (TQ) on Candida biofilms on denture acrylic and any accompanying changes in acrylic surface roughness or color. METHODS: The susceptibility of Candida species to GE and TQ was determined using the broth microdilution method and time-kill assay. A minimum biofilm eradication concentration (MBEC) assay was performed using 7-day Candida biofilms grown on denture acrylic. RESULTS: The minimum inhibitory concentration (MIC) of GE and TQ for Candida spp. was 256 and 32 µg/mL, respectively. The Candida strain complete kill rates for GE and TQ at 5-fold MIC were determined after 1 h of incubation. At 5-fold MIC, GE and TQ inhibited the preformed biofilm activity (MBEC80) of all Candida strains on denture acrylic by more than 80% after treatment for 3 h. At sub-MIC levels, GE and TQ prevented the development of C. albicans and C. tropicalis hyphae. SEM images demonstrated that GE and TQ damaged the fungal cell membrane and induced cell lysis. On the other hand, GE and TQ at 10-fold MIC did not alter the surface roughness or color of the denture acrylic. CONCLUSION: GE and TQ are interesting natural substances that could be developed as promising disinfectants for removable dentures.


Assuntos
Resinas Acrílicas , Candida , Resinas Acrílicas/farmacologia , Monoterpenos Acíclicos , Antifúngicos/farmacologia , Benzoquinonas , Biofilmes , Dentaduras/microbiologia
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