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1.
Ned Tijdschr Tandheelkd ; 128(7-8): 359-364, 2021 Jul.
Artigo em Holandês | MEDLINE | ID: mdl-34242381

RESUMO

Children are born with healthy mouths. The goal of primary prevention is to maintain this healthy situation. Starting primary prevention as early as possible, preferably at the moment of eruption of the primary teeth, is recommended. Estimating the caries risk, for example, with the help of a system such as the NOCTP method, is an important tool for deciding the check-up interval, bitewing interval and other care interventions. Prevention is always key. Active lesions may require another treatment, too, in addition to prevention. Inactive lesions as well as cleansable cavitated lesions do not require invasive treatment. Non-cleansable cavitated lesions are candidates for invasive treatment such as slicing as part of a non-restorative caries treatment (NRCT), Hall crowns or conventional restorations. The child's well-being is always the most important factor in choosing the right treatment.


Assuntos
Suscetibilidade à Cárie Dentária , Cárie Dentária , Criança , Coroas , Cárie Dentária/prevenção & controle , Humanos , Dente Decíduo
2.
Ned Tijdschr Tandheelkd ; 128(7-8): 365-370, 2021 Jul.
Artigo em Holandês | MEDLINE | ID: mdl-34242382

RESUMO

Minimally invasive dentistry is being used increasingly often, especially in paediatric dentistry. It involves replacing traditional 'drilling and filling' with treatment modalities that are tissue-saving and minimally burdensome to the patient. One of these techniques for treating carious dentine lesions is the Hall technique. A stainless-steel crown is cemented onto the primary molar without the use of anaesthesia or any form of preparation. The molar is 'sealed' under the crown and this stops the carious process in the cavity. Usually, the procedure requires 2 sessions. The Hall technique is well tolerated by children and provides the primary molar with a durable restoration. Together with this technique, the patient is also guided in an individual prevention process. The survival rates of Hall crowns are very high.


Assuntos
Cárie Dentária , Aço Inoxidável , Criança , Coroas , Cárie Dentária/terapia , Restauração Dentária Permanente , Humanos , Dente Molar , Dente Decíduo
3.
Ned Tijdschr Tandheelkd ; 128(7-8): 371-380, 2021 Jul.
Artigo em Holandês | MEDLINE | ID: mdl-34242383

RESUMO

The new KIMO guidelines 'Oral Health Care for Children' approach caries as a behavioural related disease and unequivocally assign priority to causal caries treatment, emphasising lifestyle and behavioural changes. The 5-step concept of non-restorative caries treatment (NRCT) is recommended as treatment of choice for cavitated dentine lesions in primary dentition. Communicative aspects of NRCT are supported by limited technical interventions, for the purpose of effective oral care. A balance between aetiological and symptomatic treatment is sought for each child individually, in close cooperation with the parents. Technical aspects per tooth range from limited interventions like making cavities accessible for brushing, applying fluoride varnish or SDF, covering the cavity with a layer of glass ionomer cement to emergency treatment like ART restoration or the Hall technique, in cases of necessity. Lifestyle changes lead to sustainable treatment results and enhance the quality of life of the child or young person.


Assuntos
Cárie Dentária , Qualidade de Vida , Adolescente , Criança , Cárie Dentária/terapia , Fluoretos , Cimentos de Ionômeros de Vidro , Humanos , Dente Decíduo
4.
Eur J Paediatr Dent ; 22(2): 139-143, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34238005

RESUMO

AIM: The present systematic review aims to summarise the relevant randomised clinical trials and estimate the efficacy of interceptive orthodontic intervention, in particular if an interceptive treatment with rapid maxillary expansion could be successful in managing of palatally displaced canines (PDCs). MATERIALS AND METHODS: A search strategy was developed on electronic databases including Medline, Web of Science, Scopus and Cochrane Collaboration Trial from 1925 to 2019. Two reviewers independently reviewed the sources deciding for a full reading according to the inclusion and exclusion criteria. Methodological quality criteria were applied to the selected articles. RESULTS: Three randomised clinical trials (RCTs) and one prospective longitudinal study were included in the systematic review. Generally, the intervention groups showed a higher incidence of successful eruption of PDCs (45.1% - 65.7%) compared with the control groups (13.1% - 13.6%). CONCLUSIONS: Based on the literature published, authors reached a reasonable conclusion that rapid maxillary expansion can facilitate the eruption of PDCs. Authors suggest to associate maxillary expansion with deciduous canine extraction or prevention of mesial movement of the upper first molars.


Assuntos
Técnica de Expansão Palatina , Erupção Ectópica de Dente , Dente Canino/diagnóstico por imagem , Humanos , Ortodontia Interceptora , Erupção Ectópica de Dente/diagnóstico por imagem , Erupção Ectópica de Dente/terapia , Extração Dentária , Dente Decíduo
5.
J Contemp Dent Pract ; 22(4): 388-393, 2021 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-34267008

RESUMO

AIM: This study aims to describe dental treatment provided to healthy and medically compromised patients treated under general anesthesia (GA) over a four-year period. MATERIALS AND METHODS: A total of 97 patients who received dental treatment under GA at the Saint Joseph University, Lebanon, from 2016 to 2019 were included in the study. The study population was analyzed according to the patient's age, medical status, and type of treatment done accordingly. RESULTS: The mean age of the patients was 9.15 ± 8.84 years. About 58.8% were aged below 6 years (primary dentition) and 48.5% had medical problems. Dental procedures performed were mostly extractions (4.00 ± 4.15 per patient) followed by resin composite restorations (3.66 ± 3.02 per patient). The mean number of pulpotomies per patient (p <0.001) and stainless steel crowns (p <0.001) were significantly higher in primary dentition, whereas in permanent dentition, the mean number of endodontic treatments per patient (p = 0.016) was significantly larger. Also, there was a significant difference between the type of treatment done on healthy and medically compromised patients (p <0.001). CONCLUSION: Better emphasis on oral health education and preventive strategies for children and special need patients is essential. CLINICAL SIGNIFICANCE: Dental GA is a reliable treatment for young uncooperative children and medically compromised patients. A multidisciplinary treatment plan must be conducted to ensure optimal oral healthcare and avoid unnecessary extractions.


Assuntos
Anestesia Dentária , Cárie Dentária , Adolescente , Idoso , Anestesia Geral , Criança , Pré-Escolar , Assistência Odontológica , Cárie Dentária/epidemiologia , Humanos , Lactente , Líbano , Estudos Retrospectivos , Dente Decíduo
6.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi ; 35(6): 761-768, 2021 Jun 15.
Artigo em Chinês | MEDLINE | ID: mdl-34142505

RESUMO

Objective: To investigate the effects of hypoxia inducible factor 1α (HIF-1α) overexpression on the differentiation of stem cells derived from human exfoliated deciduous teeth (SHED) into vascular endothelial cells. Methods: SHED was isolated from the retained primary teeth donated by healthy children by using collagenase digestion method. The third generation cells were identified by flow cytometry and alizarin red and alkaline phosphatase (ALP) staining after osteogenic differentiation culture. The SHED were divided into blank control group (SHED without any treatment), empty group (SHED infected with empty lentivirus), HIF-1α overexpression group (SHED infected with HIF-1α overexpression lentivirus), Wnt inhibitor group (SHED interfered by IWR-1), and combination group (HIF-1α overexpressed SHED interfered by IWR-1). Real-time fluorescence quantitative PCR (qRT-PCR) and Western blot were used to analyze the expressions of HIF-1α mRNA and protein in the SHED of blank control group, empty group, and HIF-1α overexpression group. Then the SHED in 5 groups were induced differentiation into vascular endothelial cells for 14 days. The expressions of cell surface marker molecule [von Willebrand factor (vWF) and CD31] were detected by flow cytometry. The mRNA expressions of vascular cell adhesion protein 1 (VCAM-1), KDR (Kinase-inserted domain containing receptor), and VE-cadherin (VE) were analyzed by qRT-PCR. The protein expressions of phosphate-glycogen synthasc kinase 3ß (p-GSK3ß) and ß-catenin were analyzed by Western blot. The tube forming ability of induced cells was detected by Matrigel tube forming experiment. The ability of endothelial cells to phagocytic lipid after differentiation was detected by DiI-labeled acetylated low density lipoprotein (DiI-Ac-LDL) phagocytosis. Results: After identification, the cells were SHED. After lentivirus transfection, compared with the blank control group and the empty group, the expressions of HIF-1α mRNA and protein in the HIF-1α overexpression group increased significantly ( P<0.05). Compared with the blank control group and the empty group, the expressions of VCAM-1, KDR, and VE mRNA, the percentages of vWF positive cells and CD31 positive cells, and the relative expression of ß-catenin protein were significantly higher ( P<0.05), the relative expression of p-GSK3ß protein was significantly lower ( P<0.05), the number of tubules formed and the ability to phagocytic lipids significantly increased ( P<0.05) in the HIF-1α overexpression group; while the indicators in the Wnt inhibitor group were opposite to those in the HIF-1α overexpression group ( P<0.05). Compared with the HIF-1α overexpression group, the expressions of VCAM-1, KDR, and VE mRNA, the percentages of vWF positive cells and CD31 positive cells, and the relative expression of ß-catenin protein were significantly lower ( P<0.05), the relative expression of p-GSK3ß protein was significantly higher, and the number of tubules formed and the ability of phagocytosis of lipids significantly reduced, showing significant differences between groups ( P<0.05). Conclusion: Overexpression of HIF-1α can promote SHED to differentiate into vascular endothelial cells by activating Wnt/ß-catenin signaling pathway.


Assuntos
Células Endoteliais , Subunidade alfa do Fator 1 Induzível por Hipóxia , Osteogênese , Diferenciação Celular , Criança , Humanos , Hipóxia , Subunidade alfa do Fator 1 Induzível por Hipóxia/genética , Células-Tronco , Dente Decíduo
7.
Cell Prolif ; 54(7): e13074, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34101281

RESUMO

OBJECTIVES: Pulp regeneration brings big challenges for clinicians, and vascularization is considered as its determining factor. We previously accomplished pulp regeneration with autologous stem cells from deciduous teeth (SHED) aggregates implantation in teenager patients, however, the underlying mechanism needs to be clarified for regenerating pulp in adults. Serving as an important effector of mesenchymal stem cells (MSCs), exosomes have been reported to promote angiogenesis and tissue regeneration effectively. Here, we aimed to investigate the role of SHED aggregate-derived exosomes (SA-Exo) in the angiogenesis of pulp regeneration. MATERIALS AND METHODS: We extracted exosomes from SHED aggregates and utilized them in the pulp regeneration animal model. The pro-angiogenetic effects of SA-Exo on SHED and human umbilical vein endothelial cells (HUVECs) were evaluated. The related mechanisms were further investigated. RESULTS: We firstly found that SA-Exo significantly improved pulp tissue regeneration and angiogenesis in vivo. Next, we found that SA-Exo promoted SHED endothelial differentiation and enhanced the angiogenic ability of HUVECs, as indicated by the in vitro tube formation assay. Mechanistically, miR-26a, which is enriched in SA-Exo, improved angiogenesis both in SHED and HUVECs via regulating TGF-ß/SMAD2/3 signalling. CONCLUSIONS: In summary, these data reveal that SA-Exo shuttled miR-26a promotes angiogenesis via TGF-ß/SMAD2/3 signalling contributing to SHED aggregate-based pulp tissue regeneration. These novel insights into SA-Exo may facilitate the development of new strategies for pulp regeneration.


Assuntos
Polpa Dentária/fisiologia , Exossomos/metabolismo , MicroRNAs/metabolismo , Neovascularização Fisiológica , Transdução de Sinais , Compostos de Anilina/farmacologia , Antagomirs/metabolismo , Compostos de Benzilideno/farmacologia , Diferenciação Celular/efeitos dos fármacos , Exossomos/transplante , Células Endoteliais da Veia Umbilical Humana , Humanos , MicroRNAs/antagonistas & inibidores , MicroRNAs/genética , Neovascularização Fisiológica/efeitos dos fármacos , Regeneração/efeitos dos fármacos , Transdução de Sinais/efeitos dos fármacos , Proteína Smad2/metabolismo , Proteína Smad3/metabolismo , Células-Tronco/citologia , Células-Tronco/metabolismo , Dente Decíduo/citologia , Fator de Crescimento Transformador beta/metabolismo
8.
Shanghai Kou Qiang Yi Xue ; 30(2): 177-181, 2021 Apr.
Artigo em Chinês | MEDLINE | ID: mdl-34109358

RESUMO

PURPOSE: To investigate the difference of parent's cognition of children's space loss and its influencing factors, to provide reference for children's oral health education, in order to reduce the incidence of malocclusion. METHODS: A self-designed questionnaire was used to investigate the basic information and related problems of 36 parents whose children received space loss treatment. SPSS 22.0 software package was used for statistical analysis. RESULTS: Parents paid more attention to the common oral problems of their children, the awareness of oral prevention and health care were weak, the attention to treatment was higher than that of prevention. The attitude of parents to the cognition and targeted treatment of malocclusion caused by space loss was low(27.78%), which was significantly different from that of caries (75.00%) and premature loss of deciduous teeth (63.89%). The total cognition of space loss was 61.11%. The cognitive degree of parents with different characteristics was different: the cognitive degree of parents over 50 years old was lower(14.29%), the cognitive degree of parents with higher education was higher(82.35%), there was no significant difference in cognitive degree among different gender, occupation and family monthly income groups. Parents paid more attention to the basic oral health of their children, most of the interval time between this visit and the last visit was 3 months(63.89%). The main purpose of the visit was caries or tooth pain caused by caries(63.89%). Most of parents did not know the harmful effect of space loss(72.22%). There were more parents who did not know the necessity of treatment to space loss(58.33%). Parents mainly learned the treatment to space loss through the doctor's education during dental visits(72.22%). The number of active visits were less when space loss occured(22.22%), and most of parents were recommended by dentist when they came to the clinics(72.22%). Most parents were able to accept the dentists' advice on the treatment of space loss(77.78%). CONCLUSIONS: It is necessary to strengthen the propaganda, coverage and depth of oral health education care, strengthen the awareness of oral preventive health care, especially for the parents with special personality on the importance of space loss, to prevent primary teeth caries and premature loss of primary teeth, avoid the loss of dental space, make the complete primary dentition to form a normal permanent dentition.


Assuntos
Cárie Dentária , Criança , Cognição , Cárie Dentária/epidemiologia , Humanos , Pessoa de Meia-Idade , Saúde Bucal , Pais , Inquéritos e Questionários , Dente Decíduo
9.
Braz Oral Res ; 35: e059, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34076186

RESUMO

This study aimed to verify, through a longitudinal follow-up, the pre-, peri- and postnatal factors associated with the eruption of deciduous teeth. The study was nested in a Birth Cohort Study conducted in Pelotas, a Southern Brazilian city. Mothers were followed prenatally and their children were followed-up perinatally, at 3 and 12 months of age. The outcome was the number of teeth at 12 months, and exploratory variables included maternal habits and characteristics, anthropometric measures of children and mothers, and socioeconomic and demographic information. Data were collected through interviews with the mother and children's clinical exam. Poisson regression models were used for the analysis. Participants included 4,014 children with a mean number of erupted teeth at 12 months of 5.50. After adjustments, a lower mean number of teeth was observed in children from non-white mothers, early preterm children, and shorter children at birth and at 12 months. A higher number of teeth was observed for mothers with excessive weight gain during pregnancy, mothers who smoked during pregnancy, weightier children at birth and at 12 months, and for children with larger heads at birth and at 12 months. Our findings suggest that maternal and children characteristics influenced primary tooth eruption.


Assuntos
Erupção Dentária , Dente Decíduo , Brasil/epidemiologia , Criança , Estudos de Coortes , Feminino , Humanos , Recém-Nascido , Mães , Gravidez
10.
Niger J Clin Pract ; 24(6): 919-924, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34121742

RESUMO

Background: Although the demand for esthetic filling of primary teeth with resin composite is increasing, there is no enough data on the adhesive performance of composite restorations in primary teeth. Despite the improvements in resin composites, interfacial gap is still a disadvantage as it may cause marginal staining, secondary caries, and restoration failure. Previous studies have validated the efficiency of optical coherence tomography (OCT) in the evaluation of adhesive interface in permanent teeth, but not in primary teeth. Aims: The aim of this study was to assess microleakage upon composite restorations in primary teeth using cross-polarization OCT (CP-OCT). Methodology: Cylindrical class-V cavities were prepared in extracted human primary second molars and divided into four groups randomly. In groups 1 and 2, cavities were restored using Tetric N-Universal adhesive in the self-etch mode followed by IPS Impress Direct Composite and Ceram.x One Universal composite, respectively. In groups 3 and 4, one-step self-etch Prime and Bond Elect adhesive was used followed by ID composite and CX composite in groups 3 and 4, respectively. The specimens were then immersed in a contrasting solution followed by interfacial microleakage examination under CP-OCT. The recorded images were analyzed to quantify the mean gap percentages. Results: All tested groups showed variable degree of interfacial microleakage under composite restorations. Two-way ANOVA showed the composite factor was significantly influencing the results, unlike the adhesive. Group 1 and 2 had the lowest and highest mean gap percentage, respectively, which were significantly different from the other groups. Groups 3 and 4 were not significantly different. Conclusion: Based on the current finding, a polymeric restorative system from the same manufacturer reduces the risk of interfacial microleakage in primary teeth.


Assuntos
Resinas Compostas , Tomografia de Coerência Óptica , Restauração Dentária Permanente , Humanos , Dente Molar/diagnóstico por imagem , Cimentos de Resina , Dente Decíduo
11.
Pediatr Dent ; 43(3): 205-210, 2021 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-34172114

RESUMO

Purpose: Diet is a well-established, modifiable factor influencing dental caries risk. However, evidence regarding its association with distinct clinical patterns of dental caries is lacking. The purpose of this study was to identify the association of child nutrition patterns with two distinct clinical presentations (subtypes) of childhood dental caries. Methods: The study sample comprised 120 children who were patients of a private pediatric dental practice: 30 ages one to three years (mean equals 2.2 years) with anterior carious lesions; 30 ages four to 12 years (mean equals six years) with posterior-only carious lesions; and 60 age-, gender-, and payment method-matched caries-free controls. Participants underwent dental examinations, and their guardians completed a 17-item nutrition frequency questionnaire. A latent profile analysis was used to define distinct dietary patterns and, subsequently, test their association with dental caries subtypes. Results: Dietary patterns were differentiated by consumption frequencies of water and cariogenic solid, soft, and liquid food items; a diet cluster characterized by frequent consumption of fruit juice, cereal bars, and daily vitamins was more common (P<0.05) among one- to three-year-old patients with anterior carious lesions compared to matched caries-free controls. Conclusions: These results affirm the key role of dietary patterns in childhood oral health and demonstrate the influence of fermentable carbohydrates on specific clinical subtypes of caries.


Assuntos
Cárie Dentária , Criança , Pré-Escolar , Dieta , Humanos , Lactente , Saúde Bucal , Dente Decíduo
12.
BMC Oral Health ; 21(1): 323, 2021 06 27.
Artigo em Inglês | MEDLINE | ID: mdl-34176466

RESUMO

BACKGROUND: Hypophosphatasia (HPP), a skeletal disease characterized by hypomineralization of bone and teeth, is caused by an ALPL gene mutation that leads to low activity of the tissue non-specific alkaline phosphatase enzyme. Although enzyme replacement therapy (ERT) was recently introduced for affected patients, no known studies have been reported regarding its dental effects related to permanent teeth and jaw bones. In the present study, we examined the dental effects of ERT in a case of childhood-type hypophosphatasia, including panoramic radiography findings used to estimate the dental age of permanent teeth and mandibular bone density. Furthermore, the effects of that therapy on the periodontal condition of the patient were evaluated by comparing periodontal pocket depth before and after initiation. CASE PRESENTATION: An 11-year-1-month-old boy was referred to our clinic for consultation regarding oral management. Two primary incisors had spontaneously exfoliated at 1 year 8 months old and he had been diagnosed with childhood-type HPP at the age of 2 years 2 months. Obvious symptoms were localized in the dental region at the time of diagnosis, though later extended to other parts of the body such as bone pain. ERT was started at 11 years 7 months of age, after which bone pain disappeared, and motor functions and activities of daily living improved. We estimated dental age based on tooth development stage. The age gap between chronological and dental ages was expanded before treatment, and then showed a constant decrease after ERT initiation and finally disappeared. The index for mandibular bone density (mandibular cortical width / length from mesial buccal cusp to apex of first molar) was increased after ERT initiation. Furthermore, the periodontal condition for all teeth except those exfoliated was stable after starting therapy. CONCLUSIONS: ERT resulted in improved tooth and mandibular bone mineralization, with notably good effects on teeth under formation. Acceleration of mineralization of roots associated with erupting teeth leads to stabilization of the periodontal condition. We concluded that ERT contributed to the improved dental condition seen in this patient.


Assuntos
Hipofosfatasia , Atividades Cotidianas , Fosfatase Alcalina , Calcificação Fisiológica , Pré-Escolar , Terapia de Reposição de Enzimas , Humanos , Hipofosfatasia/tratamento farmacológico , Hipofosfatasia/genética , Lactente , Masculino , Dente Decíduo
13.
Pediatr Dent ; 43(3): 170-177, 2021 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-34172109

RESUMO

Purpose: To systematically review the literature to compare the bond strength of universal adhesives with etch-and-rinse and self-etch systems to primary teeth. Methods: The search was carried out in PubMed® /MEDLINE, Scopus® , LILACS, Embase® , and Web of Science™ databases with no restrictions. Two reviewers independently selected the studies, extracted the data, and assessed the risk of bias. Direct comparisons among universal adhesive in etch-and-rinse (UER) and self-etch (USE) modes and etch-and-rinse (ER) and self-etch (SE) systems were performed considering different substrates (sound enamel and dentin, and carious dentin) through meta-analyses of random effects. A mixed treatment comparisons meta-analysis was also performed comparing the bond strength of all adhesive approaches on sound dentin. Results: From 3,276 potentially eligible studies, 18 were selected for full-text analysis, and eight were included in the systematic review. All studies included in the meta-analyses evaluated a mild universal adhesive (Scotchbond™ Universal). In direct comparisons, there was no difference between USE and SE to sound enamel (mean difference [MD] equals 5.22; 95 percent confidence interval [95% CI] equals -9.09 to 19.52). In carious dentin, the results favored only ER over USE (MD equals -3.88; 95% CI equals -7.40 to -0.37). In sound dentin, the bond strength values of UER were higher than ER (MD equals 5.50; 95% CI equals 4.03 to 6.96). The rank probability showed that the best treatment on sound dentin was UER. Conclusion: Pooled in vitro data suggest that a mild universal adhesive system can substitute the etch-and-rinse and self-etch systems for restoring primary teeth.


Assuntos
Colagem Dentária , Adesivos Dentinários , Cimentos Dentários , Dentina , Humanos , Teste de Materiais , Metanálise em Rede , Cimentos de Resina , Dente Decíduo
14.
Braz Oral Res ; 35: e078, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34161415

RESUMO

This study aimed to assess the discriminant validity of the Caries Assessment Spectrum and Treatment (CAST) at different thresholds, compared with the Decayed, Missing, and Filled Teeth Index (dmf) instrument, to discriminate caries risk factors. A cross-sectional study was conducted including children aged 2-5 years from preschools in Southern Brazil. Parents answered a questionnaire, and children were clinically examined using the CAST instrument and, in the following weeks, using the dmf index. Two caries thresholds were adopted for CAST: caries in dentin (CAST4-7/CAST2,4-8) and enamel caries (CAST3-7/CAST2-8). Poisson regression was used in the analysis (p < 0.05). A total of 200 children were included. The prevalence of caries was 47.0% with dmf, 42.5% with CAST4-7, and 77.5% with CAST3-7. When the outcome was caries prevalence, CAST4-7 discriminated between sexes, household crowding, and dental pain, and CAST3-7 discriminated age and family income, while the dmf was associated with dental pain. When experience of caries was the outcome, all the criteria discriminated between sexes, age, family income, household overcrowding, visible dental plaque, and dental pain, while dmf and CAST2-8 also discriminated maternal schooling. The CAST discriminated caries risk factors similar to the dmf index when caries experience was the outcome. When prevalence was considered, CAST was able to discriminate for more individual characteristics than dmf.


Assuntos
Aglomeração , Cárie Dentária , Brasil/epidemiologia , Criança , Pré-Escolar , Estudos Transversais , Índice CPO , Cárie Dentária/epidemiologia , Características da Família , Humanos , Prevalência , Dente Decíduo
15.
J Clin Pediatr Dent ; 45(3): 186-192, 2021 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-34192754

RESUMO

OBJECTIVE: To compare the shear bond strength (SBS) after thermocycling of four universal adhesives applied in self-etch mode on dentin and etch-and-rinse mode on enamel. STUDY DESIGN: Flat 144 buccal or lingual dentin and enamel surfaces from 72 non-carious primary molars were prepared. Samples were segregated into 12 groups (n=12): Adper Single Bond 2 etch-and-rinse (SB_T) and Clearfil SE Bond self-etch (SE_S) applied to enamel and dentin served as controls. Scotch Bond Universal Adhesive (SBU), Clearfil S3 Bond Universal Adhesive (SEU), Tetric N-Bond Universal Adhesive (TEN), and All Bond Universal (BIS) were applied in etch-and-rinse mode to enamel and in self-etch mode to dentin. They were thermocycled for 5000 cycles. SBS testing and the evaluation of fracture mode were performed. RESULTS: SB_T showed statistically higher SBS than other adhesive groups using etch-and-rinse mode on enamel. SE_S and BIS had statistically higher SBS than other adhesive groups using self-etch mode on dentin. Mixed failure was the most common failure mode in each group. CONCLUSION: The universal adhesives did not show higher SBS than SB_T when using etch-and-rinse on enamel. All universal adhesives showed higher SBS than SB_T and had SBS similar to SE_S, except SBU when using self-etch mode on dentin.


Assuntos
Colagem Dentária , Adesivos Dentinários , Esmalte Dentário , Dentina , Humanos , Teste de Materiais , Cimentos de Resina , Resistência ao Cisalhamento , Dente Decíduo
16.
J Clin Pediatr Dent ; 45(3): 147-151, 2021 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-34192758

RESUMO

Premature loss of primary molars often leads to loss of arch circumference in the primary and mixed dentition. It can lead to malpositioning and even impaction of permanent tooth, if not prevented. Space maintainers in preventive orthodontics, are imperative in maintaining arch integrity. Band and loop space maintainers are indicated whenever there is premature loss of primary molar. The conventional band and loop space maintainer is most routinely fabricated, but poses certain limitations. Three-dimensional (3D) printing in digital dentistry is one of the major developments in dentistry. It replicates the dental cast in the most accurate forms. This allows for supreme precision and minimal human errors. Besides decreasing the laboratory procedures, it has the least chance of failure or breakage. The current case report discusses 3D printing technology for the fabrication of band and loop space maintainer, which can revolutionize preventive orthodontics for children.


Assuntos
Dente Molar , Dente Decíduo , Criança , Dentição Mista , Humanos , Ortodontia Preventiva , Impressão Tridimensional , Mantenedor de Espaço em Ortodontia
17.
J Clin Pediatr Dent ; 45(3): 171-176, 2021 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-34192760

RESUMO

The purpose of this study was to determine and compare the shear force (N) required to fracture or dislodge an all-ceramic zirconia-based crown using different luting cement with those of polycarbonate crown and strip crown for the primary anterior teeth in vitro. STUDY DESIGN: Four groups of esthetic restoration for primary anterior teeth were tested for fracture strength: 1) Fifteen all-ceramic zirconia-based crowns cemented with glass ionomer cement, 2) Fifteen all-ceramic zirconia-based crowns bonded with a self-adhesive resin cement, 3) Fifteen polycarbonate crowns cemented with a polymer reinforced zinc-oxide eugenol and 4) Fifteen resin strip crowns. All restorations were placed and cemented on reproductions of dies in an independent laboratory at Delhi, India. All samples underwent loading until fracture or dislodgement with the Universal Testing Machine. The force in Newton (N) required to produce failure was recorded for each sample and the type of failures was also noted and characterized. One-way analysis of variance (ANOVA) test and the Tukey and Scheffe's post hoc comparisons were used for statistical analyses. RESULTS: In this invitro study, results were measured in Newtons (N). Group 1 (410.9±79.5 N) and Group 2 (420.5±57.8 N) had higher fracture strength than Group 3 (330.3±85.6 N) and Group 4 (268.4±28.2 N). These differences were statistically significant at P≤.05 among the sample groups. No significant difference was found between groups 1 and 2 (P = 0.984) nor between groups 3 and 4 (P =0.104). Among type of failures, majority of restoration fractures for zirconia-based crowns and resin strip crowns were due to cohesive failures and polycarbonate crowns had predominantly mixed failures. CONCLUSIONS: Under the limitations of this in vitro study, it could be concluded that all-ceramic zirconia-based crowns attained the highest fracture strength among all restorative samples tested regardless of the type of luting agent employed (P<.01). Cohesive failures were commonly observed in the zirconia crowns and resin strip crowns, whereas polycarbonate crowns revealed predominately mixed failures.


Assuntos
Estética Dentária , Resistência à Flexão , Coroas , Falha de Restauração Dentária , Análise do Estresse Dentário , Humanos , Índia , Teste de Materiais , Cimentos de Resina , Dente Decíduo , Zircônio
18.
Rev. cuba. inform. méd ; 13(1): e456, ene.-jun. 2021.
Artigo em Espanhol | LILACS, CUMED | ID: biblio-1251723

RESUMO

Cuando Gregor Mendel descubrió las leyes de la herencia, la primera acogida fue la incomprensión. Más de treinta años después, la reacción fue dividida: algunos comenzaron a aplicar su enfoque hasta lograr gigantescos avances en los estudios genéticos durante toda la primera mitad del siglo XX, otros proclamaron a la genética como una pseudociencia. La cabeza visible de esta segunda tendencia fue el ingeniero agrónomo soviético Trofim Denísovich Lysenko (1898-1976), quien afirmaba que los seres vivos podían ser modificados únicamente por el ambiente, sin tener en cuenta su herencia genética. El gran perdedor de aquella polémica fue Lysenko, y con él, la ciencia soviética, y todo lo que ello pudo implicar para el desarrollo de la medicina y la agricultura de aquel gran país. A partir de 1952 los avances de la genética y la biología molecular han marchado a pasos agigantados, y nuestro país no se ha quedado atrás: las vacunas cubanas son resultado de la aplicación de la biotecnología al combate contra el horrendo flagelo de la Covid-19. Crucial en ese avance fue el éxito del proyecto del genoma humano, cuando se lograron descifrar 3200 millones de pares de bases de ADN que contienen unos 20,500 genes. Con la culminación del proyecto del genoma humano en 2003, y en concordancia con las ideas prevalecientes entre los biólogos de aquel momento, se anticipaba que los novedosos métodos genómicos permitirían encontrar las causas y sugerir el tratamiento para las enfermedades crónicas responsables de la mayor parte de la mortalidad entre los seres humanos. Como resultado, se impulsaron estudios de asociación a escala genómica (genome-wide association studies, GWAS). Sin embargo, los resultados de tales estudios fueron bastante modestos. Así, en gemelos se encontró que las bases genéticas comunes podían explicar solamente el 8 por ciento...(AU)


Assuntos
Humanos , Dente Decíduo , Expossoma , Genética , Biologia Molecular
19.
Spectrochim Acta A Mol Biomol Spectrosc ; 260: 119966, 2021 Nov 05.
Artigo em Inglês | MEDLINE | ID: mdl-34052763

RESUMO

Teeth are characterized by a specific chemical composition and microstructure, which are related to their nature, permanent and deciduous, and to the sides, lingual and vestibular. Deeper knowledge in this topic could be useful in clinical practice to develop new strategies in restorative dentistry and in the choice of materials with the best performances. In this study, Raman MicroSpectroscopy (RMS), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Spectrometry (EDS), and Vickers MicroHardness (VMH) were exploited to: (1) identify the microstructure and the chemical/elemental composition of permanent and deciduous human teeth, also characterizing their lingual and vestibular sides, and (2) validate a new multidisciplinary analytical approach, for obtaining multiple information on calcified tissues. All applied techniques evidenced differences between permanent and deciduous teeth both in the lingual and vestibular sides. In particular, scanning electron micrographs identified areas with an irregular appearance in the vestibular and lingual sides, which presented also different VMH values. Moreover, RMS and EDS displayed a different chemical/elemental composition in outer and inner enamel and dentin, in terms of Mineral/Matrix, Crystallinity, Carbonates/phosphates, and concentrations by weight (%) of calcium, phosphorous, carbon, magnesium, and sodium. A good linear correlation was found between RMS spectral profiles and EDS and VMH measurements, suggesting that RMS may be considered a useful and non-destructive diagnostic tool for obtaining multiple information on calcified tissues.


Assuntos
Fósforo , Dente Decíduo , Humanos , Microscopia Eletrônica de Varredura , Minerais , Espectrometria por Raios X
20.
J Evid Based Dent Pract ; 21(1): 101495, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-34051951

RESUMO

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: A systematic review and meta-analysis of randomized clinical trials comparing rotary canal instrumentation techniques with manual instrumentation techniques in primary teeth. Manchanda S, Sardana D, Yiu CKY. Int Endod J. 2020;53(3):333-353. SOURCE OF FUNDING: Information not available. TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data.


Assuntos
Preparo de Canal Radicular , Dente Decíduo , Assistência Odontológica , Humanos
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