Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 4.024
Filtrar
1.
Am J Dent ; 33(1): 12-16, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32056409

RESUMO

PURPOSE: To evaluate the in vitro effects of commercially available charcoal dentifrices on Streptococcus mutans biofilm development and their ability to prevent enamel demineralization. METHODS: Streptococcus mutans biofilm was formed on polished bovine enamel specimens (n= 9 per treatment), and treated twice-daily for 120 seconds over the course of 5 days with: charcoal dentifrice containing fluoride (1,000 ppm F) (CF+), fluoride-free charcoal dentifrice (CF-), regular fluoride (1,100 ppm F) dentifrice (F+ ), or regular fluoride-free dentifrice (F-). Chlorhexidine (CHX, 0.12%) and deionized water (DIW) were used as positive and negative controls, respectively. Biofilms were analyzed for bacterial viability (colony-forming units, CFU). The pH of the medium was measured daily. Enamel specimens were analyzed using Vickers microhardness ( HV) and transversal microradiography (TMR). Data were analyzed using one-way ANOVA followed by post-hoc tests (α= 0.05). RESULTS: F+ showed higher pH values than CF+ and CF-, and CF- presented higher pH than CF+, showing that CF+ did not have inhibitory effects on the acidogenicity of cariogenic biofilms. CFU was significantly decreased when specimens were treated with CF+, CF- and F+, compared to specimens treated with DIW (P≤ 0.035) or F- (P≤ 0.001), respectively. However, the reduction observed was minimal (approximately 1 log). CF+ and CF- were less effective than F+ in preventing enamel demineralization as determined using HV (P= 0.041 and P= 0.003, respectively) and TMR ( P≤ 0.001). Both charcoal dentifrices (CF+, CF-) did not show relevant inhibition of S. mutans biofilm growth. Additionally, neither product prevented enamel demineralization compared to a regular fluoride-containing dentifrice. CLINICAL SIGNIFICANCE: The tested charcoal dentifrices did not exhibit anticaries potential.


Assuntos
Dentifrícios , Desmineralização do Dente , Animais , Biofilmes , Cariostáticos , Bovinos , Carvão Vegetal , Esmalte Dentário , Fluoretos , Fluoreto de Sódio , Streptococcus mutans , Remineralização Dentária
2.
Eur Arch Paediatr Dent ; 21(1): 85-93, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31134470

RESUMO

PURPOSE: To compare the effects of a fluoride dentifrice alone, versus a topical CPP-ACP crème used as a dentifrice, versus the combination of both agents (fluoride dentifrice followed by CPP-ACP crème) on early caries lesions (ECL) in primary anterior teeth of children over a 6-month period. METHODS: In this single blinded randomised clinical trial, children (n = 114, aged 4-5 years) with high caries risk and who had at least one ECL (ICDAS 2) on their primary anterior teeth were allocated to three groups. Subjects used different agents twice daily: fluoride dentifrice (500 ppm F, n = 42), CPP-ACP crème (10% w/v, n = 35), and the fluoride dentifrice followed by CPP-ACP crème (n = 37). Changes in lesions were tracked using QLF, comparing the baseline situation to 3 and 6 months of treatment. RESULTS: QLF changes consistent with mineral gain (∆F/fluorescence, lesion area) occurred in all three groups (baseline versus 3 months or 6 months, p ≤ 0.05 for all three groups). Differences between treatment groups were not statistically significant (p > 0.05). CONCLUSION: The topical CPP-ACP crème used alone gave effects similar to the fluoride dentifrice; however, the combination of the two did not give additive benefits over either agent used in isolation.


Assuntos
Cárie Dentária , Dentifrícios , Cariostáticos , Caseínas , Criança , Pré-Escolar , Fluoretos , Humanos , Minerais , Fluorescência Quantitativa Induzida por Luz , Remineralização Dentária
3.
Arq. odontol ; 56: 1-10, jan.-dez. 2020. ilus, tab
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-1052869

RESUMO

Objetivo: O objetivo do estudo foi avaliar o conhecimento de Graduandos da Faculdade de Odontologia da Universidade Federal de Minas Gerais (FAO-UFMG) quanto às indicações de uso de fluoretos em crianças. Métodos: Em 2015, dois grupos de estudantes foram convidados a participar do estudo: Grupo 1 (G1): 78 alunos do 1º período e Grupo 2 (G2): 72 alunos do 9º período (baseline). Em 2016, o G1 participou da reaplicação do mesmo questionário e a amostra de alunos recuperada foi de 66 graduandos (tempo 2 ­ T2). Foi realizada análise estatística dos dados usando os Testes Qui-quadrado de Pearson, Exato de Fisher e McNemar. Resultados: Comparando as respostas, houve diferenças de resposta em todas as questões entre G1 em baseline e G2 (p < 0,05). O conhecimento entre G1 no T2 e G2 foi semelhante (p > 0,05). As respostas foram diferentes entre G1 em baseline e G1 em T2 (p < 0,05), mostrando uma melhora do conhecimento para os mesmos alunos. Conclusão: No geral, pode-se dizer que ainda há uma defasagem no conhecimento, visto que muitas questões foram respondidas de maneira insatisfatória. (AU)


Aim: This study s oughtto compare the knowledge of undergraduate students from the Dental School of Universidade Federal de Minas Gerais (FOUFMG) regarding the recommendations of fluoride use for children. Methods: In 2015, two groups of students took part in the study: Group 1 (G1): 78 students from the 1stsemester and Group 2 (G2): 72 students from the last semester (baseline). In 2016, G1 answered the same questionnaire, and the sample retrieved was of 66 students (time 2). Pearson's Chi-square, Fisher's exact, and McNemar tests were used for statistical analysis. Results: Comparing the responses, the answers were different between G1 at the baseline and G2 (p < 0.05). The answers of the questionnaire were similar between G1 at time 2 and G2 at the baseline (p > 0.05). The answers were different between G1 at the baseline and G1 at time 2 (p < 0.05), illustrating an improvement in knowledge. Conclusion:In conclusion, there is still a lack of knowledge, as many questions were not properly answered by the students. (AU)


Assuntos
Estudantes de Odontologia , Criança , Odontopediatria , Conhecimento , Dentifrícios , Educação , Fluoretos/administração & dosagem , Flúor , Inquéritos e Questionários , Estudos Longitudinais , Avaliação Educacional
4.
J Contemp Dent Pract ; 20(10): 1206-1211, 2019 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-31883258

RESUMO

AIM: "Tocosh" is a potato that has undergone a process of hydraulic oxidation that enhances its antimicrobial properties so that this natural resource can be used in medical sciences. The aim of this study was to develop and evaluate the antibacterial and cytotoxic activity of a new experimental tooth based on Solanum tuberosum "Tocosh" on the cell lines 3T3 and DU145. MATERIALS AND METHODS: To evaluate the cytotoxicity, cell cultures 3T3 and DU145 were used. Cell viability was determined by the MTT assay (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) in a medium containing 10% calf serum where the cells were preincubated at a concentration of 1 × 106 cells/mL in culture medium for 3 hours at 37°C and 6.5% CO2. Then, the absorbance was measured using a microplate reader where the formazan crystals were diluted with acidic and cold isopropanol, and quantified in an ELISA reader. To evaluate the antibacterial effect, the Kirby Bauer inhibition halos method was used on strains of S. aureus (ATCC 25923), S. mutans (ATCC 25175), and S. mitis (ATCC 49456). RESULTS: Solanum tuberosum (tocosh) was not cytotoxic because it only had one CC50 at the concentration of 0.26927 mg/mL and 0.26845 mg/mL for the cell lines 3T3 and DU145, respectively. Tocosh toothpaste (TD) has an antibacterial effect against S. aureus and S. mutans. CONCLUSION: The new ecological dentifrice was not cytotoxic since it did not alter cell viability because its CC50 was only 0.268 and 0.269 µg/mL for the 3T3 and DU145 cell lines, respectively; however, it presented an optimal antimicrobial activity against the oral strains evaluated. CLINICAL SIGNIFICANCE: This research has great potential for clinical use because this new dentifrice has antimicrobial activity against different oral germs. How to cite this article: Mayta-Tovalino F, Sedano-Balbin G, Romero-Tapia P, et al. Development of New Experimental Dentifrice of Peruvian Solanum tuberosum (Tocosh) Fermented by Water Stress: Antibacterial and Cytotoxic Activity. J Contemp Dent Pract 2019;20(10):1206-1211.


Assuntos
Dentifrícios , Solanum tuberosum , Antibacterianos , Desidratação , Humanos , Testes de Sensibilidade Microbiana , Peru , Staphylococcus aureus , Cremes Dentais
5.
J Evid Based Dent Pract ; 19(4): 101349, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31843182

RESUMO

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Effect of sodium lauryl sulfate on recurrent aphthous stomatitis: A systematic review. Alli BY, Erinoso OA, Olawuyi AB. J Oral Pathol Med. 2019;48(5):358-64. SOURCE OF FUNDING: None. The authors declared no conflict of interest. TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data from double-blind randomized controlled trials.


Assuntos
Dentifrícios , Estomatite Aftosa , Método Duplo-Cego , Humanos , Dodecilsulfato de Sódio , Cremes Dentais
6.
J Clin Periodontol ; 46(12): 1205-1216, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31562774

RESUMO

AIM: To estimate gingivitis effects of a bioavailable gluconate chelated 0.454% stannous fluoride (SnF2 ) family of dentifrices in adult subjects versus positive (triclosan) and negative (NaF or MFP) controls when used ≤3 months. MATERIALS AND METHODS: A meta-analysis evaluated bioavailable gluconate chelated SnF2 dentifrices versus a negative or positive control for gingival bleeding. RESULTS: In 18 randomized controlled trials (RCTs) with 2,890 subjects assessing SnF2 paste versus a negative or positive control, the average number of bleeding sites was reduced by 51% and 31%, respectively. The average change (95% CI) in number of bleeding sites was -16.3 (-27.8, -4.9) versus the negative control and -3.6 (-5.4, -1.8) versus the positive control. Subjects with localized or generalized gingivitis had 3.7 times better odds (95% CI [2.8, 5.0]) of shifting to generally healthy using SnF2 versus a negative control and 2.8 times better odds (95% CI [2.1, 3.9]) of shifting to generally healthy using SnF2 versus a positive control. The individual study risk of bias was deemed to be low in all categories of bias. CONCLUSION: This meta-analysis demonstrates significant gingivitis benefits of bioavailable SnF2 dentifrices when used ≤3 months versus positive (triclosan) and negative (NaF or MFP) controls.


Assuntos
Dentifrícios , Gengivite , Adulto , Método Duplo-Cego , Gluconatos , Humanos , Índice Periodontal , Ensaios Clínicos Controlados Aleatórios como Assunto , Fluoreto de Sódio , Fluoretos de Estanho
7.
J Clin Pediatr Dent ; 43(5): 337-344, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31560593

RESUMO

Objective(s): The incorporation of Arginine (Arg) in NaF-containing child dentifrice might enhance its remineralizing potential, reducing fluorosis risk with significant anti-caries benefit. The study objective was to examine the remineralizing potential of arginine in child formula dentifrice (600-ppm NaF).Study Design: Primary teeth enamel specimens (n = 10) with artificial caries-like lesion were randomly divided to 4 treatment groups: A: 2% Arg-(600-ppm) NaF; B: 600-ppm NaF; C: 1100-ppm NaF; and D: deionized water subjected to 7-day pH-cycling. The mineral density (MD) of the treated specimens was assessed using micro-CT. The pre-/post-treated artificial caries-like lesion were acid-etched for enamel fluoride uptake (EFU) evaluation, Ca and P element analysis using ICP-OES, and the inorganic phosphate (PO43-) determination using colorimetric assay. Results: The percentage remineralization of the 2% Arg-NaF and 1100-ppm NaF groups was significantly higher than the 600-ppm NaF group (p<0.001). However, no significant difference in remineralization was observed between the two groups (p>0.05). The EFU, Ca/P ratio, PO43- content of the 2% Arg-NaF group were significantly higher than the 600-ppm NaF group (p<0.01); while no significant difference was found between the 2% Arg-NaF and 1100-ppm NaF groups. Conclusion: Within the limitations of the present study, incorporation of 2% arginine in 600-ppm NaF child formula dentifrice enhanced the remineralization potential of artificial enamel caries, to a level comparable to 1100-ppm NaF adult formula dentifrice.


Assuntos
Dentifrícios , Adulto , Cariostáticos , Criança , Esmalte Dentário , Fluoretos , Humanos , Fluoreto de Sódio , Remineralização Dentária
8.
Med. oral patol. oral cir. bucal (Internet) ; 24(5): e621-e629, sept. 2019. tab
Artigo em Inglês | IBECS | ID: ibc-185680

RESUMO

Background: This study aimed to analyze the efficacy of an anti-calculus mouth rinse and its possible adverse effects on the mucosa and teeth. Material and Methods: This randomized double-blind placebo-controlled clinical trial included 40 patients with treated and managed periodontal disease, all with a history of rapid calculus formation. Patients used a pyrophos-phate-based test mouth rinse (B) or a placebo (A). A range of parameters were measured for: saliva (saliva flow, pH and chemical composition); calculus (Volpe-Manhold [V-M] index, weight, and volume); adverse effects on mucosa and teeth; and the patients’ subjective perceptive of mouth rinse efficacy. Results: the test mouth rinse B produced reductions in urea, uric acid, and phosphorous, calcium, saliva flow, and increases in pH. V-M index and calculus weight decreased after using the test mouth rinse. Calculus volume decreased with both mouth rinses. No changes to the mucosa or teeth were observed. Patients perceived that the test mouth rinse was more effective


No disponible


Assuntos
Humanos , Dentifrícios , Antissépticos Bucais , Cálculos Dentários , Difosfatos , Método Duplo-Cego
9.
Int J Nanomedicine ; 14: 5243-5256, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31409987

RESUMO

Background: Dentin hypersensitivity is a common negative oral condition that can be treated with dentifrice containing hydroxyapatite (HA). The study evaluated the effect of nano-HA dentifrice on plugging the dentinal tubules for an anti-sensitivity reaction compared to a dentifrice containing common-sized particles. Also, the adsorption capacity of different particle sizes of HA mixed in a dentifrice and which is the optimal particle size was considered. Methods: Fourty premolar dentine discs and fourty molar dentine discs were randomly divided into 4 groups: distilled water group, ordinary dentifrice group and 80, 300 nm HA dentifrice group. Each dentin disc was brushed with a dentifrice twice daily at 7600 rpm under 100 g force for 2 mins for 7 consecutive days and divided into two parts, half of the dentin disc was detected by the scanning electron microscope (SEM) and energy dispersive spectrometer (EDS), the other half was brushed with distilled water and observed by SEM. One milliliter dentifrice solution (80 nm HA dentifrice, 300 nm HA dentifrice, ordinary dentifrice) was added to 50 ml potassium dichromate solution for 1, 14, and 28 d. The residual Chromium (Cr6+) concentration in the supernatant was measured by the diphenylcarbon phthalocyanine hydrazine method. The elemental constitution in the precipitate was detected by EDS. The Kruskal-Wallis test was used to analyze surface mineralization and different plugging rates of dentinal tubules. The absorption capacity of dentifrices were also evaluated by the Kruskal-Wallis test. Results: The plugging rate in the HA dentifrice group was higher than that in the ordinary dentifrice group, and the 80 nm HA dentifrice group showed the best result. The atomic percentages of Ca and P of 80 nm dentifrice group on the surface of dentinal tubules were the highest. The 80 nm HA dentifrice group showed the best adsorption and stable effect of Cr6+, followed by the 300 nm HA dentifrice group. The 300 nm HA dentifrice and the ordinary dentifrice showed desorption phenomenon. Conclusions: The dentifrice containing HA, especially the 80 nm HA dentifrice, exerts good dentinal tubule occlusion and surface mineralization effect. This dentifrice was also a good adsorbent of Cr6+.


Assuntos
Cromo/isolamento & purificação , Dentifrícios/farmacologia , Dentina/efeitos dos fármacos , Durapatita/farmacologia , Tamanho da Partícula , Adsorção , Cálcio/análise , Humanos , Fósforo/análise , Espectrometria por Raios X , Água
10.
Med Oral Patol Oral Cir Bucal ; 24(5): e621-e629, 2019 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-31433396

RESUMO

BACKGROUND: This study aimed to analyze the efficacy of an anti-calculus mouth rinse and its possible adverse effects on the mucosa and teeth. MATERIAL AND METHODS: This randomized double-blind placebo-controlled clinical trial included 40 patients with treated and managed periodontal disease, all with a history of rapid calculus formation. Patients used a pyrophosphate-based test mouth rinse (B) or a placebo (A). A range of parameters were measured for: saliva (saliva flow, pH and chemical composition); calculus (Volpe-Manhold [V-M] index, weight, and volume); adverse effects on mucosa and teeth; and the patients' subjective perceptive of mouth rinse efficacy. RESULTS: the test mouth rinse B produced reductions in urea, uric acid, and phosphorous, calcium, saliva flow, and increases in pH. V-M index and calculus weight decreased after using the test mouth rinse. Calculus volume decreased with both mouth rinses. No changes to the mucosa or teeth were observed. Patients perceived that the test mouth rinse was more effective. CONCLUSIONS: The test/B and placebo mouth rinses both modified certain parameters in saliva composition, particularly reductions in urea, uric acid, and phosphorous. Calcium tended to increase after using the test-B mouth rinse. The results did not demonstrate the anticalculus efficacy of the pyrophosphate-based mouth rinse or positive effects on saliva flow or composition. This field requires further research, as no product has been developed that prevents calculus formation completely.


Assuntos
Dentifrícios , Antissépticos Bucais , Cálculos Dentários , Difosfatos , Método Duplo-Cego , Humanos
11.
Am J Dent ; 32(3): 133-137, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31295394

RESUMO

PURPOSE: To evaluate the ability of an arginine-containing dentifrice to occlude dentin tubules. METHODS: Dentin discs were divided equally into premolar and molar groups, which were then utilized in three treatment groups: a blank control group (distilled water treatment), a negative control group (common dentifrice with calcium carbonate) and an experimental group [dentifrice with 8% (w/w) arginine]. Each dentin disk was brushed with the dentifrice twice daily for 7 consecutive days. After this period, each disc was separated into two equal halves. One half was used for scanning electron microscopy (SEM) and energy-dispersive spectrometer (EDS) examinations, while the other half was brushed with distilled water twice daily for another 7 days prior to SEM observation. RESULTS: The plugging rate in the arginine dentifrice group was significantly higher and more sustainable than in the negative control group. The surface deposition of calcium and phosphorus on the dentin discs in the arginine dentifrice group was also significantly higher. CLINICAL SIGNIFICANCE: This study provided evidence that using arginine as an active ingredient in dentifrice can improve its ability to occlude dentin tubules, thus supporting future efforts to improve dentin hypersensitivity.


Assuntos
Dentifrícios , Dessensibilizantes Dentinários , Arginina , Dentina , Cremes Dentais
12.
Am J Dent ; 32(3): 138-142, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31295395

RESUMO

PURPOSE: To compare the enamel protection efficacy of a stabilized stannous fluoride dentifrice to a triclosan-containing sodium fluoride dentifrice using a 10-day in situ erosion model, in accordance with the American Dental Association Seal of Acceptance guidelines for enamel erosion control. METHODS: In this single-center, double-blind, randomized, supervised-usage, two-treatment, four-period, crossover study, healthy adult subjects were randomized to a treatment sequence involving the following products: a 0.454% stannous fluoride (1,100 ppm F) dentifrice (Procter & Gamble) and a control dentifrice containing 0.243% sodium fluoride (1,100 ppm F) and 0.3% triclosan (Colgate-Palmolive). Each study period consisted of 10 treatment days. Subjects wore an intra-oral appliance fitted with two polished human enamel samples for 6 hours per treatment day. While wearing the appliance, subjects swished with their assigned dentifrice slurry for 60 seconds twice daily and with 250 ml orange juice over a 10-minute period four times daily. After 10 days, enamel specimens were removed and measured for surface loss using contact profilometry. RESULTS: 36 subjects were enrolled and 33 completed the study (mean age = 41.8 years). The stannous fluoride dentifrice demonstrated 90.3% less enamel loss than the NaF/triclosan dentifrice (P < 0.001) at Day 10, with median enamel loss of 0.279 µm and 2.877 µm, respectively. Both products were well tolerated. CLINICAL SIGNIFICANCE: The stannous fluoride dentifrice provided significantly greater protection against dental erosion relative to the NaF/triclosan dentifrice.


Assuntos
Esmalte Dentário , Dentifrícios , Fluoretos de Estanho , Adulto , Estudos Cross-Over , Dentifrícios/uso terapêutico , Método Duplo-Cego , Humanos , Fosfatos , Fluoretos de Estanho/uso terapêutico , Estados Unidos
13.
AAPS PharmSciTech ; 20(6): 248, 2019 Jul 08.
Artigo em Inglês | MEDLINE | ID: mdl-31286298

RESUMO

Anti-caries activity of fluoride ions is due to the protection against demineralization and the enhancement of remineralization of tooth enamel. Dentifrices available on the market contain sodium fluoride, sodium monofluorophosphate, stannous fluoride, and amine fluoride as source of these ions. A new compound working both as fluoride ion source and as abrasive was projected. Hybrids based on F- ions intercalated between the lamellae of hydrotalcite-like compounds (HTlc-F), namely MgAl-HTlc-F and ZnAl-HTlc-F, were prepared and characterized. Then, three different percentages (2, 3, and 4%) of both HTlc-F compounds were assayed. After the rheological characterization, the dentifrices containing 3 and 4% of MgAl-HTlc-F and ZnAl-HTlc-F, respectively, resulted to be the most suitable ones. Two novel in vitro methods, "rotary toothbrush method" and "manual brushing method," were developed and used in order to study the F- ions release from the prepared dentifrices. The obtained results showed that the dentifrice containing ZnAl-HTlc-F (4%) was the most effective in releasing fluoride ions. The "rotary toothbrush method" resulted to be the most suitable as the simulation of the brushing movements is standardizable and reproducible.


Assuntos
Hidróxido de Alumínio/química , Dentifrícios/química , Fluoretos/química , Hidróxido de Magnésio/química , Fosfatos/química , Remineralização Dentária , Esmalte Dentário , Técnicas In Vitro
14.
Med. oral patol. oral cir. bucal (Internet) ; 24(4): e452-e460, jul. 2019. graf, tab, ilus
Artigo em Inglês | IBECS | ID: ibc-185658

RESUMO

Background: The aim of this systematic review was to summarise the clinical information available about oral mucosal peeling (OMP) and to explore its aetiopathogenic association with dentifrices and mouthwashes. Material and Methods: PICOS outline: Population: subjects diagnosed clinically and/or pathologically. Intervention: exposition to oral hygiene products. Comparisons: patients using products at different concentrations. Out-comes: clinicopathological outcomes (primary) and oral epithelial desquamation (secondary) after use. Study de-sign: any. Exclusion criteria: reports on secondary or unpublished data, in vitro studies. Data were independently extracted by two reviewers. Results: Fifteen reports were selected from 410 identified. Descriptive studies mainly showed low bias risk, ex-perimental studies mostly an "unclear risk". Dentifrices or mouthwashes were linked to OMP, with an unknown origin in 5 subjects. Sodium lauryl-sulphate (SLS) was behind this disorder in 21 subjects, tartar-control dentifrices in 2, and flavouring agents in 1 case. Desquamation extension was linked to SLS concentration. Most cases were painless, leaving normal mucosa after desquamation. Tartar-control dentifrices caused ulcerations more frequently. Conclusions: OMP management should consider differential diagnosis with oral desquamative lesions, particularly desquamative gingivitis, with a guided clinical interview together with pathological confirmation while discouraging the use of the product responsible for OMP


No disponible


Assuntos
Humanos , Placa Dentária , Dentifrícios , Mucosa Bucal , Antissépticos Bucais , Dodecilsulfato de Sódio
15.
BMC Oral Health ; 19(1): 119, 2019 06 18.
Artigo em Inglês | MEDLINE | ID: mdl-31215467

RESUMO

OBJECTIVES: Bioactive glasses which degrade in aqueous solutions may release bioactive ions such as fluoride (F-) and support fluoride bioavailability in saliva. We investigated how these effects would be apparent in an in vivo experimental trial after toothbrushing in comparison with sodium fluoride and amine fluoride. MATERIAL AND METHODS: In this single-center, randomized, parallel in vivo trial with a three strata block design, where healthy subjects were randomly assigned into three groups. Each group brushed their teeth either with fluoridated bioactive glass containing dentifrice, with a sodium fluoride (NaF) containing dentifrice or with amine fluoride (AmF) containing toothpaste. Saliva was collected time intervals before, immediately after, 30, 60 and 120 min after toothbrushing. Fluoride concentration was determined in supernatant saliva and salivary sediment using a fluoride ion selective electrode. The data were evaluated statistically using non-parametric tests. RESULTS: The increase of bioactive fluoride in supernatant saliva was higher after application of NaF or AmF compared to fluoridated bioactive glass. In salivary sediment bioavailability of fluoride lasted longer after application of fluoridated bioactive glass. CONCLUSIONS: Toothbrushing with the fluoride containing bioactive glass dentifrices had positive effects on the fluoride bioavailability within two hours. Fluoride containing bioactive glass represent a new area for investigation in caries prophylaxis. The bioactive potential impact on the tooth remineralization should be examined further. TRIAL REGISTRATION: DRKS00016038 .


Assuntos
Cariostáticos/análise , Cárie Dentária/prevenção & controle , Dentifrícios/química , Fluoretos/análise , Saliva/química , Fluoreto de Sódio/química , Escovação Dentária , Aminas , Disponibilidade Biológica , Humanos , Saliva/metabolismo , Fatores de Tempo
16.
J Oral Sci ; 61(2): 276-283, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31217376

RESUMO

The purpose of this study was to examine the effect of desensitizing dentifrices containing stannous fluoride (SnF2) on dentinal tubule occlusion. Two experimental dentifrices with the same ingredients but different SnF2 concentrations (Group II, 0.4% w/w; Group III, 0.454% w/w) were used; distilled water was used in the control group (Group I). Third molars were collected from Japanese and American dental patients. The crowns were removed and sectioned to obtain dentin discs, which were further cut into quarters. Thirty-six specimens each from Japanese and American patients were divided into three sets (n = 12 each) and assigned to each of the three treatment groups. The specimens were brushed for 10 s twice per day for 4 days. After treatment, the discs were observed by scanning electron microscopy, and the extent of dentinal tubule occlusion in the images was expressed on a five-point categorical scale. Group II and III specimens from Japanese and American patients showed greater dentinal tube occlusion than those from Group I, but the differences were not statistically significant. The present results suggest that both SnF2 concentrations mitigate dentin hypersensitivity, regardless of patient ethnicity.


Assuntos
Dentifrícios , Sensibilidade da Dentina , Dentina , Humanos , Microscopia Eletrônica de Varredura , Fluoreto de Sódio , Fluoretos de Estanho
17.
Artigo em Inglês | MEDLINE | ID: mdl-31242669

RESUMO

Plaque accumulation and white spot lesions are common adverse effects of fixed orthodontic appliance use. This study compared the effects between enzyme-containing and conventional dentifrices on orthodontic patients. This double-blind randomized controlled trial included 42 orthodontic patients (25 women and 17 men: 22.7 ± 4.2 years) from Taipei Medical University Hospital between 2017 and 2018. The patients were randomly divided into three groups and assigned to dentifrice use during the first 3 months of the orthodontic treatment: group 1 used dentifrices containing enzymes including amyloglucosidase and glucose oxidase, group 2 used dentifrices containing 1450 ppm fluoride, and group 3 used natural dentifrices containing no chemical agent. White spot lesion index (WSL), gingival bleeding index (GBI), and visible plaque index (VPI) were recorded and analyzed. WSL, GBI, and VPI values exhibited no significant difference among the three groups. WSL increased significantly in group 3, GBI decreased significantly in all groups, and VPI decreased significantly in groups 1 and 2. No significant difference was observed between the use of enzyme-containing and conventional dentifrices after fixed orthodontic appliance placement.


Assuntos
Dentifrícios/uso terapêutico , Fluoretos/uso terapêutico , Glucana 1,4-alfa-Glucosidase/uso terapêutico , Glucose Oxidase/uso terapêutico , Adolescente , Adulto , Índice de Placa Dentária , Método Duplo-Cego , Feminino , Gengivite , Humanos , Masculino , Saúde Bucal , Aparelhos Ortodônticos , Índice Periodontal , Adulto Jovem
18.
Med Oral Patol Oral Cir Bucal ; 24(4): e452-e460, 2019 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-31246938

RESUMO

BACKGROUND: The aim of this systematic review was to summarise the clinical information available about oral mucosal peeling (OMP) and to explore its aetiopathogenic association with dentifrices and mouthwashes. MATERIAL AND METHODS: PICOS outline. Population, subjects diagnosed clinically and/or pathologically. Intervention, exposition to oral hygiene products. Comparisons, patients using products at different concentrations. Outcomes, clinicopathological outcomes (primary) and oral epithelial desquamation (secondary) after use. Study design, any. Exclusion criteria, reports on secondary or unpublished data, in vitro studies. Data were independently extracted by two reviewers. RESULTS: Fifteen reports were selected from 410 identified. Descriptive studies mainly showed low bias risk, experimental studies mostly an "unclear risk". Dentifrices or mouthwashes were linked to OMP, with an unknown origin in 5 subjects. Sodium lauryl-sulphate (SLS) was behind this disorder in 21 subjects, tartar-control dentifrices in 2, and flavouring agents in 1 case. Desquamation extension was linked to SLS concentration. Most cases were painless, leaving normal mucosa after desquamation. Tartar-control dentifrices caused ulcerations more frequently. CONCLUSIONS: OMP management should consider differential diagnosis with oral desquamative lesions, particularly desquamative gingivitis, with a guided clinical interview together with pathological confirmation while discouraging the use of the product responsible for OMP.


Assuntos
Placa Dentária , Dentifrícios , Humanos , Mucosa Bucal , Antissépticos Bucais , Dodecilsulfato de Sódio
19.
J Dent ; 86: 110-117, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-31176788

RESUMO

OBJECTIVE: Self-administered non-invasive therapies with high-fluoride dentifrices are an attractive alternative to traditional restorative management of root carious lesions (RCLs), but the available evidence is still scarce, particularly in community-dwelling elders. The aim of this randomized controlled trial (RCT) was to compare the effectiveness of toothbrushing with 5,000 ppm versus 1,450 ppm fluoridated dentifrice (F- dentifrice) on preventing and arresting RCLs, in community-dwelling elders. METHODS: A two years double-blinded RCT was carried out with 345 independently-living older adults, with at least one tooth with RCL. Participants were instructed to brush twice per day with either high-fluoride (5,000 ppm F) or the control dentifrice (1,450 ppm F). Incidence of new and arrested existing RCLs was recorded at two years and compared with the baseline data. Linear mixed regression model with repeated measures were used to test differences between groups (p < 0.05). RESULTS: The percentage of teeth with active lesions varied significantly at two years, but in opposite directions for both groups. While the control group significantly increased the mean percentage of RCLs activity from baseline to two years, from 24.32% to 40.52%, the intervention decreased the percentage of activity from 29.74% to 3.72%. The incidence of RCL was 93.5% and 35.2% in participants of the 1,450 ppm and 5,000 ppm in the F- dentifrice groups, respectively, with a relative risk (RR) of 0.10 [CI: 0.05 - 0.19]. CONCLUSION: Non-invasive treatment with 5,000 ppm F dentifrice is more effective than conventional dentifrices in preventing and arresting RCLs in community dwelling elders. ClinicalTrials.gov NCT02647203. CLINICAL SIGNIFICANCE: RCLs can be effectively prevented and arrested with the use of 5,000 ppm F dentifrice. Oral health programs directed to community-dwelling older adults might benefit from the inclusion of high fluoride dentifrice in their portfolio.


Assuntos
Cárie Dentária , Dentifrícios , Fluoretos , Cárie Radicular , Idoso , Cariostáticos , Humanos , Vida Independente , Fluoreto de Sódio
20.
ScientificWorldJournal ; 2019: 1636209, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31186619

RESUMO

Context: The comparison of fluoride levels in saliva and plaque following the use of conventional, 2800 and 5000 ppm dentifrices for different time intervals up to 24 hours has not been explored. Aim: The aim of the present study was to assess salivary and plaque fluoride levels at different time intervals following the use of high fluoride dentifrices. Study Design: This randomised control trial was conducted on sixty adolescents between the age group of 16 and 18 years divided into three groups A, B, and C. Intervention: Subjects were asked to brush the occlusal surfaces of posterior teeth with one of the dentifrices for 2 min. Unstimulated whole saliva and plaque samples were collected at different time intervals. Fluoride levels were determined using SPADNS method. Data was collected and statistically analyzed using SPSS 20 Inc. by mixed repeated measure ANOVA. Results: A significant difference in fluoride levels was observed at different time intervals in both saliva (p=0.048) and plaque (p=0.03). The variance was low with time and concentration of the dentifrice used in saliva, whereas the magnitude of treatment was large for time (>0.25) but small for (<0.09) concentration in plaque. Conclusion: A significant difference in fluoride levels was observed at different time intervals in both saliva and plaque among the three groups. There was a positive correlation between fluoride levels in saliva and plaque. Both high fluoride dentifrices were effective in maintaining higher intraoral fluoride levels up to 12 hours and 5000 ppm up to 24 hours compared to conventional dentifrice.


Assuntos
Placa Dentária/química , Dentifrícios/análise , Dentifrícios/química , Fluoretos/análise , Saliva/química , Adolescente , Feminino , Humanos , Masculino , Fatores de Tempo , Escovação Dentária , Cremes Dentais
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA