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1.
An Bras Dermatol ; 95(3): 386-389, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32312547

RESUMO

We report a 74-year-old male presented to an outpatient dermatology clinic in Manaus, Amazonas, with a one-year history of pruritic, keloidal lesions on his left lower extremity. Histopathology showed round structures in reticular dermis. Grocott methenamine silver stain revealed numerous round yeasts with thick double walls, occurring singly or in chains connected by tubular projections. The diagnosis was lobomycosis. Although the keloidal lesions presented by this patient are typical of lobomycosis, their linear distribution along the left lower limb is unusual.


Assuntos
Queloide/diagnóstico , Queloide/patologia , Dermatoses da Perna/diagnóstico , Dermatoses da Perna/patologia , Lobomicose/diagnóstico , Lobomicose/patologia , Idoso , Biópsia , Derme/microbiologia , Derme/patologia , Humanos , Masculino
3.
Wounds ; 31(9): E58-E560, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31730515

RESUMO

INTRODUCTION: Stasis mucinosis and obesity-associated lymphedematous mucinosis (OALM) have been described as 2 discrete diagnostic entities. CASE REPORT: A morbidly obese African American man in his late 60s presented to the emergency room with a 3-month history of swelling of both lower extremities and secondary changes suggestive of lymphedema and venous dermatitis. On physical examination, the patient had severe edema with multiple raised areas of verruciform skin changes and varicosities, diffuse induration, erythema, and scaling. He also had an open wound in his left hallux. The skin biopsy found mucinosis. A diagnosis of stasis mucinosis was rendered. He had normal thyroid function test laboratory results. CONCLUSIONS: The authors suggest stasis mucinosis and OALM represent the spectrum of euthyroid mucin depositional disease in varying clinical settings.


Assuntos
Dermatoses da Perna/patologia , Linfedema/patologia , Mucinoses/patologia , Obesidade Mórbida/fisiopatologia , Idoso , Bandagens Compressivas , Humanos , Dermatoses da Perna/etiologia , Linfedema/etiologia , Masculino , Mucinoses/etiologia , Obesidade Mórbida/complicações , Meias de Compressão , Resultado do Tratamento
8.
Eur J Dermatol ; 29(3): 281-286, 2019 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-31389787

RESUMO

BACKGROUND: Since the first description of adult blaschkitis (AB), the existence of this entity has been a matter of great debate. OBJECTIVES: To compare clinicopathological features of lichen striatus (LS) and AB cases. MATERIALS AND METHODS: We retrospectively reviewed the clinicopathological features of patients who clinically showed linear inflammatory dermatosis along Blaschko's lines based on a skin biopsy registry. RESULTS: Through a process of clinicopathological differential diagnosis, 27 cases of LS, three of AB, eight of linear lichen planus, and two of linear psoriasis were identified. Clinicopathological differences between LS and AB were mostly insignificant except for age at onset and multiple site involvement. In these cases, females were affected more frequently than males. The mean age at onset was 31.6 years, and the most common involved site was the leg. The lesions lasted approximately 8.3 months with few relapses. The most common histopathological finding was perivascular infiltration followed by peri-appendageal infiltration. CONCLUSION: Distinction between LS and AB appears to be unnecessary given their overlapping features.


Assuntos
Dermatite Seborreica/patologia , Erupções Liquenoides/epidemiologia , Erupções Liquenoides/patologia , Adulto , Idade de Início , Biópsia por Agulha , Estudos de Coortes , Dermatite Seborreica/epidemiologia , Dermatite Seborreica/fisiopatologia , Feminino , Seguimentos , Humanos , Imuno-Histoquímica , Incidência , Dermatoses da Perna/epidemiologia , Dermatoses da Perna/patologia , Dermatoses da Perna/fisiopatologia , Líquen Plano/epidemiologia , Líquen Plano/patologia , Líquen Plano/fisiopatologia , Erupções Liquenoides/fisiopatologia , Masculino , Pessoa de Meia-Idade , Recidiva , Estudos Retrospectivos , Índice de Gravidade de Doença
11.
Dermatol Online J ; 25(5)2019 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-31220901

RESUMO

We present a woman with a history of years of evolution of confluent hyperkeratotic papules and plaques with a generalized linear and reticulate pattern. Histopathological characteristics concordant with keratosis lichenoides chronica were finally evidenced after several non-specific biopsies. The cutaneous manifestations, chronicity. histopathology findings, and refractoriness to therapies are typical of this rare dermatosis.


Assuntos
Ceratose/patologia , Erupções Liquenoides/patologia , Idoso , Braço , Chile , Doença Crônica , Dermoscopia , Dermatoses Faciais/diagnóstico , Dermatoses Faciais/patologia , Feminino , Humanos , Ceratose/diagnóstico , Dermatoses da Perna/diagnóstico , Dermatoses da Perna/patologia , Erupções Liquenoides/diagnóstico
13.
Dermatol Online J ; 25(3)2019 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-30982302

RESUMO

Granuloma annulare (GA) is a fairly common inflammatory skin condition with a range of clinical subtypes. We describe an unusual case of unilateral GA confined to the thigh on a previously amputated limb. A man in his 80s with a past medical history of below-knee amputation of the left leg owing to severe leg ulcers from pyoderma gangrenosum, chronic lymphocytic leukemia, and dyslipidemia developed a slowly spreading eruption on the distal stump spreading proximally. On physical examination, he had numerous non-scaly violaceous papules and annular plaques from the stump to the lateral, medial, and anterior thigh. Histology confirmed a diagnosis of GA. The extensive, chronic lesions make this presentation of GA very unusual in that it shares features of both localized and generalized forms. Moreover, the temporal and spatial association with pyoderma gangrenosum is unique and may reflect a related inflammatory pathway.


Assuntos
Cotos de Amputação/patologia , Granuloma Anular/diagnóstico , Dermatoses da Perna/diagnóstico , Leucemia Linfocítica Crônica de Células B/complicações , Pioderma Gangrenoso/diagnóstico , Idoso de 80 Anos ou mais , Granuloma Anular/complicações , Granuloma Anular/patologia , Humanos , Dermatoses da Perna/complicações , Dermatoses da Perna/patologia , Masculino , Pioderma Gangrenoso/complicações , Pioderma Gangrenoso/cirurgia
15.
Dermatol Online J ; 25(2)2019 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-30865416

RESUMO

Pretibial myxedema or thyroid dermopathy constitutes dermal deposition of mucin, primarily hyaluronic acid and chondroitin sulfate. It is a manifestation of autoimmune thyroiditis, seen more in Graves disease than in Hashimoto thyroiditis. The time delay from treatment of hyperthyroidism to appearance of localized myxedema varies from one month to 16 years (mean 5.13 years). Despite a variety of therapeutic options, failure and relapse rates are high. Therapeutic options reported in the literature include compression, topical and intralesional corticosteroids, oral pentoxifylline, octreotide, rituximab, plasmapheresis, and high-dose intravenous immunoglobulin. We share our experience in two patients who were treated with electrosurgical debulking of selected longstanding myxedematous lesions, with one positive result and one negative result.


Assuntos
Procedimentos Cirúrgicos de Citorredução/métodos , Eletrocirurgia , Dermatoses do Pé/cirurgia , Dermatoses da Perna/cirurgia , Mixedema/cirurgia , Feminino , Humanos , Dermatoses da Perna/patologia , Pessoa de Meia-Idade , Mixedema/patologia
18.
Rev Soc Bras Med Trop ; 52: e20160502, 2019 Feb 14.
Artigo em Inglês | MEDLINE | ID: mdl-30785530

RESUMO

Histoid leprosy is an uncommon form of lepromatous leprosy with distinct clinical, histopathological, immunological, and bacteriological features. This variant usually occurs in multibacillary patients who have irregular or inadequate treatment. Herein, we report a case of de novo histoid leprosy diagnosed in a patient from Cali, Colombia. In endemic areas, histoid leprosy should be in the differential diagnosis of any patient presenting with skin nodules. Early diagnosis and appropriate treatment are recommended for mitigating the impact of histoid leprosy cases, which are important reservoirs of Mycobacterium leprae.


Assuntos
Hanseníase/patologia , Adulto , Biópsia , Progressão da Doença , Pavilhão Auricular/patologia , Humanos , Dermatoses da Perna/patologia , Masculino
19.
Dermatol Online J ; 25(1)2019 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-30710900

RESUMO

Bullous lupus erythematosus is a rare clinical form of lupus. The diagnosis is challenging and involves the exclusion of other subepidermal bullous dermatoses. We present a 21-year-old woman with erythematosus, polycyclic plaques with vesiculobullae along the periphery, creating an erythema gyratum repens-like pattern on acral regions. The cutaneous biopsy, analytical, and autoimmune studies support the diagnosis of systemic lupus erythematosus. Dapsone and glucocorticosteroids were given with prompt resolution of the lesions within two weeks. To our knowledge this is the first case of bullous lupus erythematosus with this atypical acral presentation.


Assuntos
Dermatoses do Pé/diagnóstico , Dermatoses da Mão/diagnóstico , Dermatoses da Perna/diagnóstico , Lúpus Eritematoso Sistêmico/diagnóstico , Dermatopatias Vesiculobolhosas/diagnóstico , Anti-Infecciosos/uso terapêutico , Dapsona/uso terapêutico , Eritema , Feminino , Dermatoses do Pé/tratamento farmacológico , Dermatoses do Pé/etiologia , Dermatoses do Pé/patologia , Glucocorticoides/uso terapêutico , Dermatoses da Mão/tratamento farmacológico , Dermatoses da Mão/etiologia , Dermatoses da Mão/patologia , Humanos , Dermatoses da Perna/tratamento farmacológico , Dermatoses da Perna/etiologia , Dermatoses da Perna/patologia , Lúpus Eritematoso Sistêmico/complicações , Lúpus Eritematoso Sistêmico/imunologia , Lúpus Eritematoso Sistêmico/patologia , Dermatopatias Vesiculobolhosas/tratamento farmacológico , Dermatopatias Vesiculobolhosas/etiologia , Dermatopatias Vesiculobolhosas/patologia , Adulto Jovem
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