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1.
Artigo em Inglês | MEDLINE | ID: mdl-35675253

RESUMO

The embodiment of virtual hand (VH) by the user is generally deemed to be important for virtual reality (VR) based hand rehabilitation applications, which may help to engage the user and promote motor skill relearning. In particular, it requires that the VH should produce task-dependent interaction behaviors from rigid to soft. While such a capability is inherent to humans via hand stiffness regulation and haptic interactions, yet it have not been successfully imitated by VH in existing studies. In this paper, we present a work which integrates biomimetic stiffness regulation and wearable finger force feedback in VR scenarios involving myoelectric control of VH. On one hand, the biomimetic stiffness modulation intuitively enables VH to imitate the stiffness profile of the user's hand in real time. On the other hand, the wearable finger force-feedback device elicits a natural and realistic sensation of external force on the fingertip, which provides the user a proper understanding of the environment for enhancing his/her stiffness regulation. The benefits of the proposed integrated system were evaluated with eight healthy subjects that performed two tasks with opposite stiffness requirements. The achieved performance is compared with reduced versions of the integrated system, where either biomimetic impedance control or wearable force feedback is excluded. The results suggest that the proposed integrated system enables the stiffness of VH to be adaptively regulated by the user through the perception of interaction torques and vision, resulting in task-dependent behaviors from rigid to soft for VH.


Assuntos
Tato , Dispositivos Eletrônicos Vestíveis , Biomimética , Desenho de Equipamento , Feminino , Humanos , Masculino , Interface Usuário-Computador
2.
Sensors (Basel) ; 22(11)2022 May 25.
Artigo em Inglês | MEDLINE | ID: mdl-35684614

RESUMO

Exoskeletons and exosuits have witnessed unprecedented growth in recent years, especially in the medical and industrial sectors. In order to be successfully integrated into the current society, these devices must comply with several commercialization rules and safety standards. Due to their intrinsic coupling with human limbs, one of the main challenges is to test and prove the quality of physical interaction with humans. However, the study of physical human-exoskeleton interactions (pHEI) has been poorly addressed in the literature. Understanding and identifying the technological ways to assess pHEI is necessary for the future acceptance and large-scale use of these devices. The harmonization of these evaluation processes represents a key factor in building a still missing accepted framework to inform human-device contact safety. In this review, we identify, analyze, and discuss the metrics, testing procedures, and measurement devices used to assess pHEI in the last ten years. Furthermore, we discuss the role of pHEI in safety contact evaluation. We found a very heterogeneous panorama in terms of sensors and testing methods, which are still far from considering realistic conditions and use-cases. We identified the main gaps and drawbacks of current approaches, pointing towards a number of promising research directions. This review aspires to help the wearable robotics community find agreements on interaction quality and safety assessment testing procedures.


Assuntos
Exoesqueleto Energizado , Robótica , Desenho de Equipamento , Humanos , Robótica/métodos
3.
Sci Rep ; 12(1): 10445, 2022 Jun 21.
Artigo em Inglês | MEDLINE | ID: mdl-35729240

RESUMO

The optimization work of a newly proposed 20-in. photomultiplier tube based on dynode and microchannel plates (Dynode-MCP-PMT) are conducted in this paper. Three-dimensional models are developed in CST STUDIO SUITE to systematically investigate the effects of the size and bias voltage of the two focusing electrodes, dynode and the glass envelop handle based on the Finite Integral Technique and Monte Carlo method. Results predict that the collection efficiency and the transit time spread of the optimized design are substantially improved which are 100% and 3.7 ns.


Assuntos
Desenho de Equipamento , Eletrodos , Método de Monte Carlo
4.
Biosensors (Basel) ; 12(6)2022 Jun 06.
Artigo em Inglês | MEDLINE | ID: mdl-35735540

RESUMO

Blood glucose concentration is important for metabolic homeostasis in humans and animals. Many diabetic patients need to detect blood glucose daily which burdens community hospitals and family healthcare. Optical fiber sensors are widely used in biomedical detection because of their compact structure, fast response, high sensitivity, low cost, and ease of operation. In this work, we constructed a Fabry-Perot (FP) cavity biosensor for the fast detection of glucose concentration in serum. The femtosecond laser micromachining was applied to fabricate the FP cavity by printing the fiber-tip fixed-supported bridge at the end face of the optical fiber. An additional hemisphere was printed at the center of the outer surface of the bridge to avoid multi-beam interference. The results demonstrated that the proposed biosensor had high refractive index (RI) detection sensitivity, roughly 1039 nm/RIU at a wavelength of 1590 nm, and the detection sensitivity for glucose was around 0.185 nm/ (mg/mL) at a wavelength of 1590 nm. Due to its high sensitivity, compact structure, and fast response, the FP cavity biosensor has great potential to be applied in family healthcare for glucose concentration detection of diabetic patients.


Assuntos
Tecnologia de Fibra Óptica , Interferometria , Glicemia , Desenho de Equipamento , Humanos , Refratometria
5.
Biosensors (Basel) ; 12(6)2022 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-35735562

RESUMO

The measurement of small changes in the refractive index (RI) leads to a comprehensive analysis of different biochemical substances, paving the way to non-invasive and cost-effective medical diagnosis. In recent times, the liquid biopsy for cancer detection via extracellular vesicles (EV) in the bodily fluid is becoming very popular thanks to less invasiveness and stability. In this context, here we propose a highly sensitive RI sensor based on a compact high-index-coated polymer waveguide Bragg grating with a metal under cladding. Owing to the combined effect of a metal under cladding and a high-index coating, a significant enhancement in the RI sensitivity as well as the dynamic range has been observed. The proposed sensor has been analyzed by combining finite element method (FEM) and coupled-mode theory (CMT) approaches, demonstrating a sensitivity of 408-861 nm/RIU over a broad dynamic range of 1.32-1.44, and a strong evanescent field within a 150 nm proximity to the waveguide surface compliant with EV size. The aforementioned performance makes the proposed device suitable for performing real-time and on-chip diagnoses of cancer in the early stage.


Assuntos
Técnicas Biossensoriais , Vesículas Extracelulares , Desenho de Equipamento , Polímeros , Refratometria
6.
PLoS One ; 17(6): e0268542, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35675288

RESUMO

Proper respiratory tract protection is the key factor to limiting the rate of COVID-19 spread and providing a safe environment for health care workers. Traditional N95 (FFP2) respirators are not easy to regenerate and thus create certain financial and ecological burdens; moreover, their quality may vary significantly. A solution that would overcome these disadvantages is desirable. In this study a commercially available knit polyester fleece fabric was selected as the filter material, and a total of 25 filters of different areas and thicknesses were prepared. Then, the size-resolved filtration efficiency (40-400 nm) and pressure drop were evaluated at a volumetric flow rate of 95 L/min. We showed the excellent synergistic effect of expanding the filtration area and increasing the number of filtering layers on the filtration efficiency; a filter cartridge with 8 layers of knit polyester fabric with a surface area of 900 cm2 and sized 25 × 14 × 8 cm achieved filtration efficiencies of 98% at 95 L/min and 99.5% at 30 L/min. The assembled filter kit consists of a filter cartridge (14 Pa) carried in a small backpack connected to a half mask with a total pressure drop of 84 Pa at 95 L/min. In addition, it is reusable, and the filter material can be regenerated at least ten times by simple methods, such as boiling. We have demonstrated a novel approach for creating high-quality and easy-to-breathe-through respiratory protective equipment that reduces operating costs and is a green solution because it is easy to regenerate.


Assuntos
COVID-19 , Dispositivos de Proteção Respiratória , Aerossóis , COVID-19/prevenção & controle , Desenho de Equipamento , Filtração/métodos , Humanos , Máscaras , Teste de Materiais/métodos , Poliésteres
7.
Sci Rep ; 12(1): 9433, 2022 Jun 08.
Artigo em Inglês | MEDLINE | ID: mdl-35676407

RESUMO

This work proposes a compact metasurface (MS)-integrated wideband multiple-input multiple-output (MIMO) antenna for fifth generation (5G) sub-6 GHz wireless communication systems. The perceptible novelty of the proposed MIMO system is its wide operating bandwidth, high gain, lower interelement gap, and excellent isolation within the MIMO components. The radiating patch of the antenna is truncated diagonally with a partially ground plane, and a metasurface has been employed for enhancing the antenna performance. The suggested MS integrated single antenna prototype has a miniature dimension of 0.58λ × 0.58λ × 0.02λ. The simulated and measured findings demonstrate a wideband characteristic starting from 3.11 to 7.67 GHz including a high realized gain of 8 dBi. The four-element MIMO system has been designed by rendering each single antenna orthogonally to one another while retaining compact size and wideband properties between 3.2 and 7.6 GHz. The suggested MIMO prototype has been designed and fabricated on a low loss Rogers RT5880 substrate with a miniature dimension of 1.05λ × 1.05λ × 0.02λ and its performance is evaluated using a suggested 10 × 10 array of a square enclosed circular split ring resonators within the same substrate material. The inclusion of the proposed metasurface with a backplane significantly reduces antenna backward radiation and manipulates the electromagnetic field, thus improving the bandwidth, gain and isolation of MIMO components. The suggested 4-port MIMO antenna offers a high realized gain of 8.3 dBi compared to existing MIMO antennas with an excellent average total efficiency of 82% in the 5G sub-6 GHz spectrum and is in good accordance with measured results. Furthermore, the developed MIMO antenna exhibits outstanding diversity characteristics in respect of envelope correlation coefficient (ECC) less than 0.004, diversity gain (DG) close to 10 dB (> 9.98 dB) and high isolation between MIMO components (> 15.5 dB). Therefore, the proposed MS-inspired MIMO antenna substantiates its applicability for 5G sub-6 GHz communication networks.


Assuntos
Procedimentos Cirúrgicos Refrativos , Tecnologia sem Fio , Desenho de Equipamento
8.
BMC Anesthesiol ; 22(1): 177, 2022 Jun 08.
Artigo em Inglês | MEDLINE | ID: mdl-35676618

RESUMO

BACKGROUND: Although there are at least seven manufacturers producing left-sided double-lumen tubes (DLTs), there have been few reports comparing the segments of these DLTs. In this study, we compared various segments of left-sided DLTs further. MATERIALS AND METHODS: We examined five manufacturers' left-sided DLTs: Mallinckrodt, Portex, Rüsch, Sheridan, and Daiken-medical. We conducted the following six trials or measurements, and three supplemental trials or measurements: First, we tried to pass various sizes of steel balls down each lumen in order from the smallest (3 mm) to largest (4.5 mm). If the ball passed on the first attempt, we tried just once; otherwise, we made a second attempt. Second, we measured the external diameter of tracheal and bronchial cuff using a profile projector. Third, we measured the length of the cuff and tip of the bronchial segment of the tubes using the profile projector. Fourth, we measured various lengths of the tubes. Fifth, we measured the external diameter of both lumens and the tubules for tracheal and bronchial cuff inflation. Finally, we measured various cross-sectional areas including the tracheal lumen, bronchial lumen, and tubules for cuff inflation. We also conducted three supplemental studies. First, we measured air volume in the cuff when intracuff pressure equaled 2 or 3 kPa. Second, we defined the configuration of the tracheal and bronchial cuffs. Third, we defined the presence or absence of bevels and also measured the angle of the bevels using the profile projector. RESULTS: We performed nine trials and measurements and found large disparities between each manufacturer's tubes. CONCLUSIONS: The large disparities found between the measurements of the five manufacturers' tubes may be due to different lots or changes in specifications made by each manufacturer. We found tubes exhibiting lower quality, such as deformations, and non-universal and inconsistent sizing, in the comparison of the manufacturers' tubes. Practitioners should be aware of the features and aspects of these tubes.


Assuntos
Intubação Intratraqueal , Traqueia , Brônquios , Desenho de Equipamento
9.
BMC Oral Health ; 22(1): 225, 2022 Jun 08.
Artigo em Inglês | MEDLINE | ID: mdl-35676648

RESUMO

BACKGROUND: Toothbrushes require flexibility to access all dental surfaces and remove plaque effectively, but they should also aim to prevent or limit overbrushing and consequent damage to teeth and gums. In two studies, the physical properties and cleaning performance of specialist test toothbrushes with flexible necks were compared to a reference rigid-necked toothbrush. METHODS: In Study 1, a universal testing machine (Instron E 10,000) with a specially designed setup was used to test the deflection behaviour of toothbrush head and neck. Untufted toothbrushes were fixed in a custom holder and force was applied to the head while the deflection was measured. In Study 2, one control and five test toothbrushes were assessed using a robot system to simulate the cleaning of artificial plaque from defined surfaces of artificial replicated human teeth in a model oral cavity (typodonts). RESULTS: Study 1 showed that the flexible-neck toothbrush deflected 2 to 2.5 times more than the rigid-neck reference toothbrush when same force was applied to the toothbrush head. Study 2 revealed that all five test toothbrushes showed statistically superior simulated plaque removal to the reference toothbrush. This superiority was observed for all test toothbrushes employing horizontal and rotating brushing action (all p = 0.001) but only three of the five toothbrushes when vertical brushing was employed (all p = 0.001). Cleaning efficacy of the test toothbrushes was demonstrated both interdentally and at the gumline locations. The Complete Protection toothbrush showed the most effective cleaning performance followed by the Repair and Protect and Rapid Relief toothbrushes. CONCLUSION: The addition of a flexible-neck component to the toothbrush designs helped to reduce stiffness and may allow more effective cleaning compared to rigid designs with controlled force distribution on the teeth and gums. This may help to provide plaque control at all potential risk areas in an in vitro robot model and could support good oral hygiene in-use.


Assuntos
Placa Dentária , Robótica , Placa Dentária/prevenção & controle , Índice de Placa Dentária , Desenho de Equipamento , Humanos , Testes Mecânicos , Escovação Dentária
10.
Zhongguo Yi Liao Qi Xie Za Zhi ; 46(3): 254-258, 2022 May 30.
Artigo em Chinês | MEDLINE | ID: mdl-35678431

RESUMO

The high incidence of cardiovascular diseases is a serious threat to human health, and endovascular surgery has become the standard treatment for most interventional cardiovascular diseases. The robotassisted endovascular surgery system further enhances surgeons' ability to perform minimally invasive endovascular procedures in interventional cardiology. This study presents a new robotic technique for coronary intervention from the perspective of clinical application. Aiming at clinical application scenarios, this scheme proposed an intuitive guide wire catheter mechanism design, which accurately and perfectly simulates the doctor's hand movements, realizes the positive and negative direction translation of the guide wire catheter, accurate torque control of the guide wire rotation and locking. The results of animal test showed that the R-OneTM has a high degree of dexterity, accuracy and stability,and meets the clinical needs.


Assuntos
Doenças Cardiovasculares , Procedimentos Cirúrgicos Robóticos , Robótica , Animais , Cateterismo , Desenho de Equipamento
11.
Zhongguo Yi Liao Qi Xie Za Zhi ; 46(3): 283-286, 2022 May 30.
Artigo em Chinês | MEDLINE | ID: mdl-35678437

RESUMO

An integrated digital magnetic resonance imaging spectrometer was proposed in this study. By using the FPGA chip Artix7 200T, timing control, data processing, digital frequency conversion and phase control were implemented into a single-chip, thus effectively improved timing accuracy and phase accuracy, while avoided the structural design complexity caused by multi-board connection and improved system integration and imaging quality.


Assuntos
Imageamento por Ressonância Magnética , Desenho de Equipamento
12.
Sensors (Basel) ; 22(11)2022 May 30.
Artigo em Inglês | MEDLINE | ID: mdl-35684767

RESUMO

With the remarkable advances in vertical-cavity surface-emitting lasers (VCSELs) in recent decades, VCSELs have been considered promising light sources in the field of optical wireless communications. However, off-the-shelf VCSELs still have a limited modulation bandwidth to meet the multi-Gb/s data rate requirements imposed on the next-generation wireless communication system. Recently, employing machine learning (ML) techniques as a method to tackle such issues has been intriguing for researchers in wireless communication. In this work, through a systematic analysis, it is shown that the ML technique is also very effective in VCSEL-based visible light communication. Using a commercial VCSEL and bidirectional long short-term memory (Bi-LSTM)-based ML scheme, a high-speed visible light communication (VLC) link with a data rate of 13.5 Gbps is demonstrated, which is the fastest single channel result from a cost-effective, off-the-shelf VCSEL device, to the best of the authors' knowledge.


Assuntos
Lasers , Luz , Comunicação , Desenho de Equipamento , Redes Neurais de Computação
13.
Sensors (Basel) ; 22(11)2022 May 31.
Artigo em Inglês | MEDLINE | ID: mdl-35684813

RESUMO

The article considers the potential applicability of C12880MA and C11708MA Hamamatsu microspectrometers, which are characterized by an extremely compact design, occupying a small volume of several cubic centimeters, in portable spectrometric equipment with spatial resolution for monitoring the optical properties of condensed scattering media. The development of methods for determining the reduced scattering and absorption spectral coefficients of radiation from various scattering materials and products allows us to speak about the possibility of real-time control of the volume concentration of optically active components included in them, for example, fat and water in dairy products. For this, it is necessary to provide sufficiently accurate spectra of diffusely reflected broadband light radiation at different distances between the points of radiation entrance and registration. The aim of the manuscript is to assess the possibility of using the considered microspectrometers in compact devices for optical diagnostics and control of the optical properties of condensed scattering media. The features of the connection diagram of these microspectrometers and the necessary methods for correcting the initially obtained spectral dependencies of diffusive reflection, which will be of interest to developers of spectral diagnostic equipment, are considered in detail. The need to eliminate the influence of the inhomogeneity of dark counts of a CMOS photodiode array is shown. The hardware functions of the C12880MA and C11708MA Hamammatsu microspectrometers, as well as the AvaSpec 2048L fiber-optic spectrometer, were experimentally measured and compared. Methods for correcting the nonlinearity of their reading scales and light characteristics, as well as improving their equivalent spectral resolution using digital Wiener filtering, are described. It is shown that the equivalent spectral resolution of C12880MA and C11708MA microspectrometers can be improved by about 40% when recording smooth spectra, subject to the condition that the resulting side oscillations are small. It is pointed out that in order to reduce the level of side oscillations in the corrected spectra with improved resolution, it is necessary to ensure the smoothness of the original spectra and a good signal-to-noise ratio. A conclusion is made about the possibility of using the considered microspectrometers in portable spectrometric equipment with careful consideration of their characteristics, the features of their switching circuit, and the necessary software.


Assuntos
Tecnologia de Fibra Óptica , Refratometria , Desenho de Equipamento , Espalhamento de Radiação , Análise Espectral/métodos
14.
Sensors (Basel) ; 22(11)2022 Jun 03.
Artigo em Inglês | MEDLINE | ID: mdl-35684892

RESUMO

People with visual impairment are the second largest affected category with limited access to assistive products. A complete, portable, and affordable smart assistant for helping visually impaired people to navigate indoors, outdoors, and interact with the environment is presented in this paper. The prototype of the smart assistant consists of a smart cane and a central unit; communication between user and the assistant is carried out through voice messages, making the system suitable for any user, regardless of their IT skills. The assistant is equipped with GPS, electronic compass, Wi-Fi, ultrasonic sensors, an optical sensor, and an RFID reader, to help the user navigate safely. Navigation functionalities work offline, which is especially important in areas where Internet coverage is weak or missing altogether. Physical condition monitoring, medication, shopping, and weather information, facilitate the interaction between the user and the environment, supporting daily activities. The proposed system uses different components for navigation, provides independent navigation systems for indoors and outdoors, both day and night, regardless of weather conditions. Preliminary tests provide encouraging results, indicating that the prototype has the potential to help visually impaired people to achieve a high level of independence in daily activities.


Assuntos
Equipamentos de Autoajuda , Auxiliares Sensoriais , Pessoas com Deficiência Visual , Bengala , Desenho de Equipamento , Humanos
15.
Sci Rep ; 12(1): 9571, 2022 Jun 10.
Artigo em Inglês | MEDLINE | ID: mdl-35688958

RESUMO

In recent years, wall-climbing robots have begun to replace manual work at heights to reduce economic losses and casualties caused by working at heights. This paper designs a negative pressure adsorption type wall-climbing robot and analyzes the internal fluid movement state of its negative pressure device and the force analysis of the robot when it is adsorbed and balanced. Furthermore, through the experimental prototype, the influence of wall material, robot pose, negative pressure cavity shape and sealing method on the adsorption performance of the wall-climbing robot is explored. The computational fluid dynamics simulation (CFD) simulation method and experimental results are used to verify each other, which proves the correctness of the simulation results. Based on the Kriging surrogate model, the functional relationship between the impeller blade outlet angle, the impeller inlet diameter, the number of blades as the design variables, the negative pressure as the dependent variable was established, and the genetic algorithm (GA) was used to optimize it. Compared with the original design, the optimized design results of impeller parameters have increased the negative pressure value from 3534.75 to 4491.19 Pa, an increase of 27.06%.


Assuntos
Hidrodinâmica , Robótica , Simulação por Computador , Desenho de Equipamento , Análise Espacial
16.
Anal Chem ; 94(23): 8523-8532, 2022 Jun 14.
Artigo em Inglês | MEDLINE | ID: mdl-35658120

RESUMO

Nuclear magnetic resonance (NMR) spectroscopy has played an integral role in medical and environmental metabolic research. However, smaller biological entities, such as eggs and small tissue samples, are becoming increasingly important to better understand toxicity, biological growth/development, and diseases. Unfortunately, their small sizes make them difficult to study using conventional 5 mm NMR probes due to limited sensitivity. The use of microcoil NMR holds great potential for the analysis of such samples, where the coil can be designed to match the sample size to significantly improve NMR mass sensitivity and the filling factor. Here, we compare the potential of planar and Helmholtz microcoil designs to execute complex experiments for the analysis of intact, mass-limited biological samples. The planar coil offers the advantage of an open access design, potentially allowing flow systems to be incorporated and varying sample sizes to be studied; however, its relatively inhomogeneous B1 field leads to reduced NMR performance. The Helmholtz microcoil overcomes this drawback with its symmetrical design, improving B1 homogeneity across the sample but with the caveat that the size and shape of the sample is limited to the spacing between the two parallel coils. The line shape, sensitivity, and RF performance are compared on both coils using standard samples and biological samples. This study found that the Helmholtz microcoil used here considerably outperforms the planar coil in multipulse experiments and has great potential to study complex biological samples in the 50-200 nL range.


Assuntos
Imageamento por Ressonância Magnética , Desenho de Equipamento , Espectroscopia de Ressonância Magnética/métodos
17.
G Ital Cardiol (Rome) ; 23(6): 454-460, 2022 Jun.
Artigo em Italiano | MEDLINE | ID: mdl-35674036

RESUMO

Leadless, intracardiac pacemakers are a major innovation in the management of bradyarrhythmia. Both safety and feasibility of leadless pacing have been assessed in acute settings and mid-term follow-up showing a significant reduction of pacing-related complications as compared with standard transvenous pacemakers. There are many advantages of the leadless approach including a reduction of infection risk and malfunction due to the absence of transvenous leads and the pacemaker pocket. Patients at high risk of endocarditis or pocket failure, with compromised venous access, can benefit from the leadless approach. In this review article, the relevant implant indications for leadless pacemaker and patient populations are described.


Assuntos
Endocardite , Marca-Passo Artificial , Bradicardia , Estimulação Cardíaca Artificial , Desenho de Equipamento , Humanos
18.
Opt Lett ; 47(11): 2923-2926, 2022 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-35648965

RESUMO

Reconstructive micro-spectrometers have shown great potential in many fields such as medicine, agriculture, and astronomy. However, the performance of these spectrometers is seriously limited by the spectral varieties of response pixels and anti-noise ability of reconstruction algorithms. In this work, we propose a spectral reconstruction (SR) algorithm, whose anti-noise ability is at least four times better than the current algorithms. A micro-spectrometer is realized by fabricating a large number of Fabry-Perot (FP) micro-filters onto a cheap complementary metal-oxide semiconductor (CMOS) chip for demonstration by using a very high-efficiency technology of nano-imprinting. Nano-imprint technology can complete hundreds of spectral pixels with rich spectral features at one time and with low cost. In cooperation with the SR algorithm, such a micro-spectrometer can have a spectral resolution as high as 3 nm with much lower angular sensitivity than a photonic crystal-based micro-spectrometer. It can obtain the target's spectrum from only a single shot, which has wide applications in spectral analysis etc.


Assuntos
Algoritmos , Refratometria , Desenho de Equipamento , Óptica e Fotônica , Semicondutores
19.
Int Heart J ; 63(3): 504-509, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35650152

RESUMO

Pulmonary vein (PV) isolation (PVI) by continuous, transmural and durable lesions is decisive for ensuring long-term freedom from atrial fibrillation (AF). AF ablation requires irrigated tip catheters to reduce thromboembolic complications. This precluded temperature-controlled delivery of radiofrequency (RF) energy.The aim of this study was to evaluate feasibility, acute efficacy, and safety of an irrigated, temperature-controlled ablation catheter [DiamondTemp™ (DT) Medtronic®] for PVI.Consecutive patients with AF underwent PVI using the DT catheter combined with high-power short-duration RF applications. Ablation settings were (1) a catheter tip temperature limit of 60°C, (2) a temperature-controlled power of 50 W, and (3) application duration of 10 seconds. The primary endpoint was acute isolation of PVs, reassessed after a 30-minute waiting period. Secondary endpoints included procedural parameters (defined as a catheter tip temperature of 50°C > 3 seconds, an impedance drop of 5-10 Ω) and the occurrence of serious adverse events.Fifty consecutive patients [mean age 66 ± 12 years, 38 (76%) women, 24 patients with paroxysmal AF (48%)] were included. Median procedure and left atrial dwell time was 89 [68; 107] and 63 [52; 79] minutes, respectively. Mean number of RF applications was 59 ± 20, and mean total RF duration was 14 ± 6 minutes. Acute PVI was achieved in all patients solely using DT ablation. Acute PV reconnection within the waiting period occurred in five patients; all reconnected PVs were successfully reisolated. One major complication occurred.In this study, the DT ablation system demonstrated high acute efficacy for PVI. Temperature-controlled ablation in conjunction with high-power short-duration applications might be effectively supported.


Assuntos
Fibrilação Atrial , Ablação por Cateter , Veias Pulmonares , Idoso , Fibrilação Atrial/cirurgia , Ablação por Cateter/métodos , Desenho de Equipamento , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Veias Pulmonares/cirurgia , Resultado do Tratamento
20.
Comput Intell Neurosci ; 2022: 2447263, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35665294

RESUMO

According to the characteristics and division rules of the modules, this paper divides the rotary module, the swing module, and the mobile module. In order to realize the rapid identification of modules, according to the basic principles of module design, the above modules are put into the module library established by Access. According to the modular modeling method, kinematic models are established, respectively. In order to automatically establish the kinematic model of the robot, a unified expression of modules is established. According to the unified expression of the modules, the kinematics of the reconfigurable robot is analyzed. According to the characteristics of the configuration plane, the configuration plane is divided, and the expression form of the position and attitude of the configuration plane is given. Combined with the principle of neural network and multimodal information fusion, a multimodal information fusion model based on long- and short-term memory neural network is established. Aiming at the control problem of mechanically driven reconfigurable robots, a specific long- and short-term memory neural network model is designed, and the long- and short-term memory neural network algorithm is applied to the robot control problem based on multimodal information fusion. The design of the controller and driver of each joint is the basis of the distributed control system. This paper discusses the hardware design of the joint controller and driver and the realization of the position control system and discusses the method of realizing distributed control based on the Modbus protocol of RS485 communication. Through the comprehensive experiment of the configuration, the point control and the continuous path control are carried out to verify the correctness of the theoretical analysis of the system and the reliability of the system hardware and software operation.


Assuntos
Robótica , Fenômenos Biomecânicos , Desenho de Equipamento , Redes Neurais de Computação , Reprodutibilidade dos Testes , Robótica/métodos
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