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1.
Indian J Public Health ; 64(Supplement): S117-S124, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32496240

RESUMO

Digital health interventions are globally playing a significant role to combat coronavirus disease 2019 (COVID-19), which is an infectious disease caused by Severe Acute Respiratory Syndrome coronavirus 2. Here, we present a very brief overview of the multifaceted digital interventions, globally, and in India, for maintaining health and health-care delivery, in the context of the Covid-19 pandemic.


Assuntos
Infecções por Coronavirus/epidemiologia , Sistemas de Informação/organização & administração , Aplicativos Móveis , Pneumonia Viral/epidemiologia , Inteligência Artificial , Betacoronavirus , Confidencialidade , Infecções por Coronavirus/prevenção & controle , Infecções por Coronavirus/terapia , Diagnóstico Precoce , Educação em Saúde/métodos , Humanos , Internet das Coisas/organização & administração , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Pneumonia Viral/terapia , Prevenção Primária/organização & administração , Design de Software , Telemedicina/métodos , Telemedicina/organização & administração , Dispositivos Eletrônicos Vestíveis
2.
Einstein (Sao Paulo) ; 18: eAO5023, 2020.
Artigo em Inglês, Português | MEDLINE | ID: mdl-31994606

RESUMO

OBJECTIVE: To adapt an antibiotic dose adjustment software initially developed in English, to Portuguese and to the Brazilian context. METHODS: This was an observational, descriptive study in which the Delphi method was used to establish consensus among specialists from different health areas, with questions addressing the visual and operational aspects of the software. In a second stage, a pilot experimental study was performed with the random comparison of patients for evaluation and adaptation of the software in the real environment of an intensive care unit, where it was compared between patients who used the standardized dose of piperacillin/tazobactam, and those who used an individualized dose adjusted through the software Individually Designed and Optimized Dosing Strategies. RESULTS: Twelve professionals participated in the first round, whose suggestions were forwarded to the software developer for adjustments, and subsequently submitted to the second round. Eight specialists participated in the second round. Indexes of 80% and 90% of concordance were obtained between the judges, characterizing uniformity in the suggestions. Thus, there was modification in the layout of the software for linguistic and cultural adequacy, minimizing errors of understanding and contradictions. In the second stage, 21 patients were included, and there were no differences between doses of piperacillin in the standard dose and adjusted dose Groups. CONCLUSION: The adapted version of the software is safe and reliable for its use in Brazil.


Assuntos
Anti-Infecciosos/administração & dosagem , Linguística/normas , Piperacilina/administração & dosagem , Design de Software , Tazobactam/administração & dosagem , Idoso , Idoso de 80 Anos ou mais , Antropometria , Brasil , Comparação Transcultural , Técnica Delfos , Feminino , Humanos , Unidades de Terapia Intensiva , Masculino , Pessoa de Meia-Idade , Padrões de Referência , Reprodutibilidade dos Testes , Estatísticas não Paramétricas , Inquéritos e Questionários
3.
Nucleic Acids Res ; 48(D1): D971-D976, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31584086

RESUMO

As the largest ethnic group in the world, the Han Chinese population is nonetheless underrepresented in global efforts to catalogue the genomic variability of natural populations. Here, we developed the PGG.Han, a population genome database to serve as the central repository for the genomic data of the Han Chinese Genome Initiative (Phase I). In its current version, the PGG.Han archives whole-genome sequences or high-density genome-wide single-nucleotide variants (SNVs) of 114 783 Han Chinese individuals (a.k.a. the Han100K), representing geographical sub-populations covering 33 of the 34 administrative divisions of China, as well as Singapore. The PGG.Han provides: (i) an interactive interface for visualization of the fine-scale genetic structure of the Han Chinese population; (ii) genome-wide allele frequencies of hierarchical sub-populations; (iii) ancestry inference for individual samples and controlling population stratification based on nested ancestry informative markers (AIMs) panels; (iv) population-structure-aware shared control data for genotype-phenotype association studies (e.g. GWASs) and (v) a Han-Chinese-specific reference panel for genotype imputation. Computational tools are implemented into the PGG.Han, and an online user-friendly interface is provided for data analysis and results visualization. The PGG.Han database is freely accessible via http://www.pgghan.org or https://www.hanchinesegenomes.org.


Assuntos
Grupo com Ancestrais do Continente Asiático/genética , Bases de Dados Genéticas , Genética Populacional , Genoma Humano , Genômica , China , Grupos Étnicos/genética , Genômica/métodos , Humanos , Software , Design de Software , Navegador
4.
Nucleic Acids Res ; 48(D1): D45-D50, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31724722

RESUMO

The Bioinformation and DDBJ Center (https://www.ddbj.nig.ac.jp) in the National Institute of Genetics (NIG) maintains a primary nucleotide sequence database as a member of the International Nucleotide Sequence Database Collaboration (INSDC) in partnership with the US National Center for Biotechnology Information and the European Bioinformatics Institute. The NIG operates the NIG supercomputer as a computational basis for the construction of DDBJ databases and as a large-scale computational resource for Japanese biologists and medical researchers. In order to accommodate the rapidly growing amount of deoxyribonucleic acid (DNA) nucleotide sequence data, NIG replaced its supercomputer system, which is designed for big data analysis of genome data, in early 2019. The new system is equipped with 30 PB of DNA data archiving storage; large-scale parallel distributed file systems (13.8 PB in total) and 1.1 PFLOPS computation nodes and graphics processing units (GPUs). Moreover, as a starting point of developing multi-cloud infrastructure of bioinformatics, we have also installed an automatic file transfer system that allows users to prevent data lock-in and to achieve cost/performance balance by exploiting the most suitable environment from among the supercomputer and public clouds for different workloads.


Assuntos
Biologia Computacional/métodos , Bases de Dados de Ácidos Nucleicos , Genômica/métodos , Software , Navegador , Japão , Design de Software
5.
Nucleic Acids Res ; 48(D1): D1145-D1152, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31686107

RESUMO

The ProteomeXchange (PX) consortium of proteomics resources (http://www.proteomexchange.org) has standardized data submission and dissemination of mass spectrometry proteomics data worldwide since 2012. In this paper, we describe the main developments since the previous update manuscript was published in Nucleic Acids Research in 2017. Since then, in addition to the four PX existing members at the time (PRIDE, PeptideAtlas including the PASSEL resource, MassIVE and jPOST), two new resources have joined PX: iProX (China) and Panorama Public (USA). We first describe the updated submission guidelines, now expanded to include six members. Next, with current data submission statistics, we demonstrate that the proteomics field is now actively embracing public open data policies. At the end of June 2019, more than 14 100 datasets had been submitted to PX resources since 2012, and from those, more than 9 500 in just the last three years. In parallel, an unprecedented increase of data re-use activities in the field, including 'big data' approaches, is enabling novel research and new data resources. At last, we also outline some of our future plans for the coming years.


Assuntos
Biologia Computacional/métodos , Bases de Dados de Proteínas , Proteômica/métodos , Big Data , Mineração de Dados , Software , Design de Software , Navegador
6.
Nucleic Acids Res ; 48(D1): D992-D1005, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31680154

RESUMO

The volume of biological, chemical and functional data deposited in the public domain is growing rapidly, thanks to next generation sequencing and highly-automated screening technologies. These datasets represent invaluable resources for drug discovery, particularly for less studied neglected disease pathogens. To leverage these datasets, smart and intensive data integration is required to guide computational inferences across diverse organisms. The TDR Targets chemogenomics resource integrates genomic data from human pathogens and model organisms along with information on bioactive compounds and their annotated activities. This report highlights the latest updates on the available data and functionality in TDR Targets 6. Based on chemogenomic network models providing links between inhibitors and targets, the database now incorporates network-driven target prioritizations, and novel visualizations of network subgraphs displaying chemical- and target-similarity neighborhoods along with associated target-compound bioactivity links. Available data can be browsed and queried through a new user interface, that allow users to perform prioritizations of protein targets and chemical inhibitors. As such, TDR Targets now facilitates the investigation of drug repurposing against pathogen targets, which can potentially help in identifying candidate targets for bioactive compounds with previously unknown targets. TDR Targets is available at https://tdrtargets.org.


Assuntos
Quimioinformática/métodos , Biologia Computacional/métodos , Bases de Dados Factuais , Descoberta de Drogas/métodos , Genômica/métodos , Software , Reposicionamento de Medicamentos , Genoma , Humanos , Ferramenta de Busca , Design de Software , Interface Usuário-Computador
7.
Nucleic Acids Res ; 48(D1): D1022-D1030, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31680168

RESUMO

Assessing the causal tissues of human traits and diseases is important for better interpreting trait-associated genetic variants, understanding disease etiology, and improving treatment strategies. Here, we present a reference database for trait-associated tissue specificity based on genome-wide association study (GWAS) results, named Tissue-Specific Enrichment Analysis DataBase (TSEA-DB, available at https://bioinfo.uth.edu/TSEADB/). We collected GWAS summary statistics data for a wide range of human traits and diseases followed by rigorous quality control. The current version of TSEA-DB includes 4423 data sets from the UK Biobank (UKBB) and 596 from other resources (GWAS Catalog and literature mining), totaling 5019 unique GWAS data sets and 15 770 trait-associated gene sets. TSEA-DB aims to provide reference tissue(s) enriched with the genes from GWAS. To this end, we systematically performed a tissue-specific enrichment analysis using our recently developed tool deTS and gene expression profiles from two reference tissue panels: the GTEx panel (47 tissues) and the ENCODE panel (44 tissues). The comprehensive trait-tissue association results can be easily accessed, searched, visualized, analyzed, and compared across the studies and traits through our web site. TSEA-DB represents one of the many timely and comprehensive approaches in exploring human trait-tissue association.


Assuntos
Bases de Dados Genéticas , Estudo de Associação Genômica Ampla , Herança Multifatorial , Locos de Características Quantitativas , Característica Quantitativa Herdável , Perfilação da Expressão Gênica/métodos , Predisposição Genética para Doença , Estudo de Associação Genômica Ampla/métodos , Humanos , Especificidade de Órgãos/genética , Software , Design de Software , Navegador
8.
Nucleic Acids Res ; 48(D1): D1051-D1056, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31602484

RESUMO

VDJbase is a publicly available database that offers easy searching of data describing the complete sets of gene sequences (genotypes and haplotypes) inferred from adaptive immune receptor repertoire sequencing datasets. VDJbase is designed to act as a resource that will allow the scientific community to explore the genetic variability of the immunoglobulin (Ig) and T cell receptor (TR) gene loci. It can also assist in the investigation of Ig- and TR-related genetic predispositions to diseases. Our database includes web-based query and online tools to assist in visualization and analysis of the genotype and haplotype data. It enables users to detect those alleles and genes that are significantly over-represented in a particular population, in terms of genotype, haplotype and gene expression. The database website can be freely accessed at https://www.vdjbase.org/, and no login is required. The data and code use creative common licenses and are freely downloadable from https://bitbucket.org/account/user/yaarilab/projects/GPHP.


Assuntos
Biologia Computacional/métodos , Bases de Dados Genéticas , Genótipo , Haplótipos , Receptores Imunológicos/genética , Recombinação V(D)J , Humanos , Anotação de Sequência Molecular , Receptores de Antígenos de Linfócitos B/genética , Receptores de Antígenos de Linfócitos T/genética , Software , Design de Software , Navegador , Fluxo de Trabalho
9.
Nucleic Acids Res ; 48(D1): D51-D57, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31665430

RESUMO

Enhancers are a class of cis-regulatory elements that can increase gene transcription by forming loops in intergenic regions, introns and exons. Enhancers, as well as their associated target genes, and transcription factors (TFs) that bind to them, are highly associated with human disease and biological processes. Although some enhancer databases have been published, most only focus on enhancers identified by high-throughput experimental techniques. Therefore, it is highly desirable to construct a comprehensive resource of manually curated enhancers and their related information based on low-throughput experimental evidences. Here, we established a comprehensive manually-curated enhancer database for human and mouse, which provides a resource for experimentally supported enhancers, and to annotate the detailed information of enhancers. The current release of ENdb documents 737 experimentally validated enhancers and their related information, including 384 target genes, 263 TFs, 110 diseases and 153 functions in human and mouse. Moreover, the enhancer-related information was supported by experimental evidences, such as RNAi, in vitro knockdown, western blotting, qRT-PCR, luciferase reporter assay, chromatin conformation capture (3C) and chromosome conformation capture-on-chip (4C) assays. ENdb provides a user-friendly interface to query, browse and visualize the detailed information of enhancers. The database is available at http://www.licpathway.net/ENdb.


Assuntos
Biologia Computacional/métodos , Bases de Dados Genéticas , Elementos Facilitadores Genéticos , Genômica/métodos , Animais , Humanos , Camundongos , Software , Design de Software , Interface Usuário-Computador , Navegador
10.
Nucleic Acids Res ; 48(D1): D933-D940, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31612961

RESUMO

The GWAS Central resource provides a toolkit for integrative access and visualization of a uniquely extensive collection of genome-wide association study data, while ensuring safe open access to prevent research participant identification. GWAS Central is the world's most comprehensive openly accessible repository of summary-level GWAS association information, providing over 70 million P-values for over 3800 studies investigating over 1400 unique phenotypes. The database content comprises direct submissions received from GWAS authors and consortia, in addition to actively gathered data sets from various public sources. GWAS data are discoverable from the perspective of genetic markers, genes, genome regions or phenotypes, via graphical visualizations and detailed downloadable data reports. Tested genetic markers and relevant genomic features can be visually interrogated across up to sixteen multiple association data sets in a single view using the integrated genome browser. The semantic standardization of phenotype descriptions with Medical Subject Headings and the Human Phenotype Ontology allows the precise identification of genetic variants associated with diseases, phenotypes and traits of interest. Harmonization of the phenotype descriptions used across several GWAS-related resources has extended the phenotype search capabilities to enable cross-database study discovery using a range of ontologies. GWAS Central is updated regularly and available at https://www.gwascentral.org.


Assuntos
Biologia Computacional/métodos , Bases de Dados Genéticas , Estudo de Associação Genômica Ampla , Genômica , Genótipo , Fenótipo , Software , Ontologia Genética , Estudo de Associação Genômica Ampla/métodos , Genômica/métodos , Design de Software , Interface Usuário-Computador , Navegador
11.
Nucleic Acids Res ; 48(D1): D1085-D1092, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31624841

RESUMO

To date, large amounts of genomic and phenotypic data have been accumulated in the fields of crop genetics and genomic research, and the data are increasing very quickly. However, the bottleneck to using big data in breeding is integrating the data and developing tools for revealing the relationship between genotypes and phenotypes. Here, we report a rice sub-database of an integrated omics knowledgebase (MBKbase-rice, www.mbkbase.org/rice), which integrates rice germplasm information, multiple reference genomes with a united set of gene loci, population sequencing data, phenotypic data, known alleles and gene expression data. In addition to basic data search functions, MBKbase provides advanced web tools for genotype searches at the population level and for visually displaying the relationship between genotypes and phenotypes. Furthermore, the database also provides online tools for comparing two samples by their genotypes and finding target germplasms by genotype or phenotype information, as well as for analyzing the user submitted SNP or sequence data to find important alleles in the germplasm. A soybean sub-database is planned for release in 3 months and wheat and maize will be added in 1-2 years. The data and tools integrated in MBKbase will facilitate research in crop functional genomics and molecular breeding.


Assuntos
Biologia Computacional/métodos , Bases de Dados Genéticas , Genômica/métodos , Oryza/genética , Melhoramento Vegetal , Genes de Plantas , Genoma de Planta , Genótipo , Software , Design de Software , Interface Usuário-Computador , Navegador
12.
J Thorac Cardiovasc Surg ; 159(3): 1130-1138, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-31606178

RESUMO

OBJECTIVE: Use of 3-dimensional computed tomography for preoperative and intraoperative simulation has been introduced in the field of thoracic surgery. However, 3-dimensional computed tomography provides only static simulation, which is a significant limitation of surgical simulation. Dynamic simulation, reflecting the intraoperative deformation of the lung, has not been developed. The aim of this study was to develop a novel simulation system that generates dynamic images based on patient-specific computed tomography data. METHODS: We developed an original software, the Resection Process Map, for anatomic pulmonary resection. The Resection Process Map semi-automatically generates virtual dynamic images based on patient-specific computed tomography data. We retrospectively evaluated its accuracy in 18 representative cases by comparing the virtual dynamic images with the actual surgical images. RESULTS: In this study, 9 patients who underwent lobectomy and 9 patients who underwent segmentectomy were included. For each case, a virtual dynamic image was successfully generated semi-automatically by the Resection Process Map. The Resection Process Map accurately delineated 98.6% of vessel branches and all the bronchi. The median time required to obtain the images was 121.3 seconds. CONCLUSIONS: We successfully developed a novel dynamic simulation system, the Resection Process Map, for anatomic pulmonary resection.


Assuntos
Imageamento Tridimensional , Pulmão/cirurgia , Modelagem Computacional Específica para o Paciente , Pneumonectomia/métodos , Interpretação de Imagem Radiográfica Assistida por Computador , Cirurgia Assistida por Computador , Tomografia Computadorizada por Raios X , Idoso , Feminino , Humanos , Pulmão/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Retrospectivos , Design de Software , Fatores de Tempo
13.
Nucleic Acids Res ; 48(D1): D111-D117, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31617563

RESUMO

LnCeVar (http://www.bio-bigdata.net/LnCeVar/) is a comprehensive database that aims to provide genomic variations that disturb lncRNA-associated competing endogenous RNA (ceRNA) network regulation curated from the published literature and high-throughput data sets. LnCeVar curated 119 501 variation-ceRNA events from thousands of samples and cell lines, including: (i) more than 2000 experimentally supported circulating, drug-resistant and prognosis-related lncRNA biomarkers; (ii) 11 418 somatic mutation-ceRNA events from TCGA and COSMIC; (iii) 112 674 CNV-ceRNA events from TCGA; (iv) 67 066 SNP-ceRNA events from the 1000 Genomes Project. LnCeVar provides a user-friendly searching and browsing interface. In addition, as an important supplement of the database, several flexible tools have been developed to aid retrieval and analysis of the data. The LnCeVar-BLAST interface is a convenient way for users to search ceRNAs by interesting sequences. LnCeVar-Function is a tool for performing functional enrichment analysis. LnCeVar-Hallmark identifies dysregulated cancer hallmarks of variation-ceRNA events. LnCeVar-Survival performs COX regression analyses and produces survival curves for variation-ceRNA events. LnCeVar-Network identifies and creates a visualization of dysregulated variation-ceRNA networks. Collectively, LnCeVar will serve as an important resource for investigating the functions and mechanisms of personalized genomic variations that disturb ceRNA network regulation in human diseases.


Assuntos
Bases de Dados Genéticas , Variação Genética , Genômica/métodos , Interferência de RNA , RNA/genética , Software , Biomarcadores , Regulação da Expressão Gênica , Redes Reguladoras de Genes , Sequenciamento de Nucleotídeos em Larga Escala , Design de Software , Interface Usuário-Computador , Navegador
14.
Nucleic Acids Res ; 48(D1): D956-D963, 2020 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-31410488

RESUMO

Numerous studies indicate that non-coding RNAs (ncRNAs) have critical functions across biological processes, and single-nucleotide polymorphisms (SNPs) could contribute to diseases or traits through influencing ncRNA expression. However, the associations between SNPs and ncRNA expression are largely unknown. Therefore, genome-wide expression quantitative trait loci (eQTL) analysis to assess the effects of SNPs on ncRNA expression, especially in multiple cancer types, will help to understand how risk alleles contribute toward tumorigenesis and cancer development. Using genotype data and expression profiles of ncRNAs of >8700 samples from The Cancer Genome Atlas (TCGA), we developed a computational pipeline to systematically identify ncRNA-related eQTLs (ncRNA-eQTLs) across 33 cancer types. We identified a total of 6 133 278 and 721 122 eQTL-ncRNA pairs in cis-eQTL and trans-eQTL analyses, respectively. Further survival analyses identified 8312 eQTLs associated with patient survival times. Furthermore, we linked ncRNA-eQTLs to genome-wide association study (GWAS) data and found 262 332 ncRNA-eQTLs overlapping with known disease- and trait-associated loci. Finally, a user-friendly database, ncRNA-eQTL (http://ibi.hzau.edu.cn/ncRNA-eQTL), was developed for free searching, browsing and downloading of all ncRNA-eQTLs. We anticipate that such an integrative and comprehensive resource will improve our understanding of the mechanistic basis of human complex phenotypic variation, especially for ncRNA- and cancer-related studies.


Assuntos
Biologia Computacional/métodos , Bases de Dados Genéticas , Neoplasias/genética , Locos de Características Quantitativas , RNA não Traduzido , Alelos , Perfilação da Expressão Gênica/métodos , Regulação Neoplásica da Expressão Gênica , Predisposição Genética para Doença , Estudo de Associação Genômica Ampla/métodos , Genótipo , Humanos , Polimorfismo de Nucleotídeo Único , Software , Design de Software , Interface Usuário-Computador , Navegador
15.
J Forensic Nurs ; 16(1): 36-46, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31299671

RESUMO

INTRODUCTION: Corrections agencies are exploring ways to securely and cost-effectively increase access to high-quality, evidence-based educational programs for personnel. Technology-based instructional tools hold strong potential for continuing education. The Institute for Healthcare Improvement's Framework for Going to Full Scale was employed to guide a systematic approach. PURPOSE: The purpose of this article is to outline and describe the design and development of a media-rich interactive computer-based learning product, Enhancing Care for Aged and Dying in Prison, which addresses geriatric and end-of-life care issues in corrections. METHOD: Through an iterative process, the research team developed the computer-based educational program that included program and module-specific objectives in alignment with goals and priorities of the end users, detailed evidence-based content that was engaging and visually appealing, and assessments aimed at testing the user's knowledge. RESULTS: The Enhancing Care for Aged and Dying in Prison contains six modules, created under the careful guidance of the research team and the two advisory boards. Contents, including images and testimonials, were selected purposefully and strategically. Module objectives were developed in alignment with the goals and priorities of each module, and assessments tested user knowledge level pre/post module exposure. Completion of the training product advances the research and development necessary to further the goal of full-scale dissemination of the computer-based education. DISCUSSION/CONCLUSIONS: The goal of this program is to enhance care and improve quality of life for aged and dying inmates. Evidence-based training products are critical in preparing not only forensic nurses who work in corrections but also the broader group of correctional personnel in how to better meet the care needs of incarcerated persons.


Assuntos
Instrução por Computador , Geriatria/educação , Prisioneiros , Design de Software , Assistência Terminal , Idoso , Humanos , Desenvolvimento de Programas , Interface Usuário-Computador
16.
J Infect Public Health ; 13(4): 491-496, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31831397

RESUMO

OBJECTIVE: The objective is to understand the role of information management systems in the public health perspective of primary care units more accurately. METHODS: A public health information management system for primary medical units, which is based on electronic health records, virtual private network technology, real-time data storage, and other technologies, is designed on the premise of economical and straightforward operation. Besides, Xinhua Community Health Service Center Around the Wulong Street, Longsha District, Qiqihar City is selected as the experimental unit of the public health information management system, and the work efficiency of the system in the public health perspective of the primary medical unit is evaluated after 12 months of system operation. RESULTS: The public health information management system of primary medical units has following comprehensive management functions: health record management, child health, maternal health, health of the elderly, health of patients with chronic diseases, health of severe psychiatric patients, health education, infectious diseases and public emergencies, health events, health supervision, and management information. In addition, after 12 months of information management system operates in the grassroots units, the results show that patients and doctors have a very high satisfaction rate with the system. The system not only cultivates the excellent health and disease prevention awareness of residents but also improves the efficiency of primary care institutions, as well as reducing the number of patients seeking medical cares. CONCLUSION: The public health information management system of primary health care units based on medical and health information design is rich in functions with prominent work efficiency, which significantly improves the public health of grass-roots medical units. The research is useful and significant for follow-up studies on public health care systems.


Assuntos
Gestão da Informação em Saúde , Sistemas de Informação Administrativa , Atenção Primária à Saúde , Administração em Saúde Pública , Registros Eletrônicos de Saúde , Gestão da Informação em Saúde/métodos , Humanos , Atenção Primária à Saúde/métodos , Administração em Saúde Pública/métodos , Design de Software
19.
Am J Clin Pathol ; 153(1): 94-98, 2020 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-31433839

RESUMO

OBJECTIVES: Thyroid and rheumatologic autoimmune testing are areas where evidence-based guidance from specialty organizations and Choosing Wisely support utilizing screening tests for autoimmune and thyroid disorders prior to more specialized testing. Adjustment of the orderable options in the electronic health record (EHR) can influence ordering patterns without requiring manual review or additional effort by the clinician. METHODS: The menu was adjusted to reflect recommendations from Choosing Wisely to favor screening tests that automatically reflex to specialized testing on primary care providers' preference lists. Effectiveness was evaluated by reviewing total orders for individual tests. RESULTS: Shifts in ordering from individual screening tests (antinuclear antibody and thyrotropin) to ones that reflexed to specialized testing were observed in parallel with significant reductions in the corresponding specialized testing. CONCLUSIONS: Optimization of the EHR laboratory ordering menu can be used to shift ordering patterns toward Choosing Wisely recommendations.


Assuntos
Registros Eletrônicos de Saúde , Sistemas de Registro de Ordens Médicas , Padrões de Prática Médica/estatística & dados numéricos , Design de Software , Algoritmos , Anticorpos Antinucleares/análise , Humanos , New Jersey , Reflexo , Centros de Atenção Terciária , Tireotropina/análise
20.
Rev. cuba. inform. méd ; 11(2)jul.-dic. 2019.
Artigo em Espanhol | LILACS, CUMED | ID: biblio-1093330

RESUMO

El Instituto de Medicina Tropical Pedro Kouri (IPK) es una institución con un alto nivel científico, que desarrolla una formación docente de excelencia en doctorados, maestrías, residencias y otros entrenamientos relacionados con las enfermedades tropicales, su diagnóstico y tratamiento. La biblioteca, referencia en esta rama de la medicina, posee un fondo documental que se encuentra desactualizado, los documentos que forman parte de su colección son ediciones antiguas. Se hace necesario establecer una estrategia para la actualización y gestión de la información. Se realizó una búsqueda de información en internet para tener una visión sobre las herramientas y software utilizados para el desarrollo de bibliotecas digitales. Entre las herramientas consultadas y probadas se seleccionó el gestor de biblioteca de libros electrónicos Calibre por ser el software libre que más se adecuaba a nuestras necesidades. Se gestionó, reajustó y organizó la literatura en formato digital con el objetivo de establecer una estrategia para la actualización de la información, con la finalidad de satisfacer las necesidades de los usuarios(AU)


The IPK is an institution with a high scientific level, which develops teaching of excellence in doctorates, masters, residences and other trainings related to tropical diseases, their diagnosis and treatment. The library, a reference in this branch of medicine, has a documentary collection that is outdated, the documents that are part of its collection are old editions. It is necessary to establish a strategy for updating and managing information. An information search was carried out on the internet to have a vision on the tools and software used for the development of digital libraries. Among the tools consulted and tested, the Caliber e-book library manager was selected as the free software that best suited our needs. The literature was managed, readjusted and organized in digital format with the aim of establishing a strategy for updating information, in order to meet the needs of users(AU)


Assuntos
Design de Software , Software , Doenças Transmissíveis/diagnóstico , Doenças Transmissíveis/tratamento farmacológico , Automação de Bibliotecas/normas , Serviços de Biblioteca , Estudos Prospectivos
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