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2.
Epidemiol Health ; 41: e2019029, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31319658

RESUMO

OBJECTIVES: This study analyzed Korea National Health and Nutrition Examination Survey data from 2007 to 2017 to assess trends in the prevalence, treatment, and control of diabetes in Korean adults ≥30 years of age. METHODS: Prevalent diabetes was defined as a fasting plasma glucose level ≥126 mg/dL, self-reported use of anti-diabetic treatment (insulin or oral anti-diabetic drugs), or diabetes diagnosis by a physician. Target levels were defined as glycosylated hemoglobin <6.5% or <7.0%, blood pressure <130/80 mmHg, and total cholesterol <200 mg/dL. All survey waves were age-standardized to the 2005 Korean census population. RESULTS: Diabetes prevalence increased from 9.6% in 2007-2009 to 10.8% in 2016-2017 (p<0.001). Impaired fasting glucose prevalence significantly increased in both genders and almost every age group. Diabetes awareness and glycemic control did not show an increasing trend; however, the treatment rate and proportion of people diagnosed with diabetes achieving target blood pressure and total cholesterol levels improved from 57.2% to 63.5% (p=0.008), from 41.1% to 53.2% (p<0.001), and from 65.0% to 78.0% (p<0.001), respectively. CONCLUSIONS: From 2007 to 2017, the prevalence of diabetes increased moderately in Korea, whereas the diabetes treatment rate and the proportion of people diagnosed with diabetes achieving target blood pressure and total cholesterol levels improved. However, awareness of diabetes and glycemic control require significant improvements. A national-level action plan is required to raise awareness about diabetes and prediabetes, with the goal of improving glycemic control and minimizing the occurrence of adverse health outcomes.


Assuntos
Diabetes Mellitus/epidemiologia , Diabetes Mellitus/terapia , Adulto , Idoso , Diabetes Mellitus/prevenção & controle , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos Nutricionais , Prevalência , República da Coreia/epidemiologia
4.
Rev Saude Publica ; 53: 45, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31066823

RESUMO

OBJECTIVE: To address the implementation of the Lab for Innovation in Chronic Conditions in Santo Antonio do Monte, indicating the main challenges and lessons of a new chronic condition model. METHODS: This is an observational study based on two sources of data: 1) two cross-sectional household surveys, 2013 (2012 as reference year) and 2015 (2014 as reference year), representative for the entire population and four target groups (pregnant women; children under two years old; individuals with hypertension and diabetes); medical records of individuals who self-reported having hypertension or diabetes in the household survey of 2013. A descriptive statistics analysis was performed. RESULTS: The main findings showed that the public health system is the main provider of health services, mainly primary care, in Santo Antonio do Monte. Besides, the implementation of Lab for Innovation in Chronic Conditions showed the importance of building a Primary Health Care network in small municipalities. CONCLUSIONS: Community health agents and health managers played a fundamental role in the Primary Health Care network. The case study of Santo Antonio do Monte poses some challenges and lessons that clarify future interventions on building a Primary Health Care network that is essential to provide an adequate and longitudinal care to chronic conditions.


Assuntos
Serviços de Saúde Comunitária/normas , Diabetes Mellitus/epidemiologia , Diabetes Mellitus/prevenção & controle , Hipertensão/epidemiologia , Hipertensão/prevenção & controle , Atenção Primária à Saúde/normas , Adolescente , Adulto , Idoso , Brasil/epidemiologia , Pré-Escolar , Doença Crônica , Agentes Comunitários de Saúde , Estudos Transversais , Características da Família , Feminino , Acesso aos Serviços de Saúde/estatística & dados numéricos , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Programas Nacionais de Saúde , Gravidez , Valores de Referência , Medição de Risco , Fatores de Risco , Fatores de Tempo , Adulto Jovem
5.
S D Med ; 72(3): 131-132, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31018060

RESUMO

This article discusses the historical trauma and modern struggles of Oglala Lakota Sioux tribal members on the Pine Ridge Indian Reservation in southwestern South Dakota. In order for healthcare providers to understand why patients from this region have soaring rates of diabetes, teen pregnancies and premature death, it is important to have exposure to their culture and daily life. As part of their medical school curriculum, students at the Sanford School of Medicine take part in cultural immersion trips in order to better understand and relate to the people on the Pine Ridge Reservation. These experiences are led by local Lakota people and allow students to be exposed to the modern healthcare and government facilities, and also take part in traditional ceremonies such as drumming circles and art shows. By the end of the journey, future physicians leave with a better understanding of day-to-day Lakota life and increased empathy and understanding for their Native American counterparts.


Assuntos
Assistência à Saúde Culturalmente Competente , Diabetes Mellitus/etnologia , Diabetes Mellitus/prevenção & controle , Índios Norte-Americanos , Gravidez na Adolescência , Adolescente , Adulto , Assistência à Saúde , Feminino , Humanos , Masculino , Gravidez , Gravidez na Adolescência/etnologia , Gravidez na Adolescência/prevenção & controle , South Dakota
6.
BMC Public Health ; 19(1): 409, 2019 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-30991978

RESUMO

BACKGROUND: India accounts for more than two-third of mortality due to non-communicable diseases (NCDs) in south-east Asia. The burden is high in Karnataka, one of the largest states in southern India. There is a need for integration of disease prevention, health promotion, treatment and care within the national program at primary level. A public-private partnership initiative explored evidence gaps to inform a health system based, integrated NCD programme across care continuum with a focus on hypertension and diabetes. METHODS: The study was conducted during 2017-18 in urban parts of Mysore city, covering a population of 58,000. Mixed methods were used in the study; a population-based screening to estimate denominators for those with disease and at risk; cross-sectional surveys to understand distribution of risk factors, treatment adherence and out of pocket expenses; facility audits to assess readiness of public and private facilities; in-depth interviews and focus group discussions to understand practices, myths and perceptions in the community. Chi-square tests were used to test differences between the groups. Framework analysis approach was used for qualitative analysis. RESULTS: Twelve and 19% of the adult population had raised blood sugar and blood pressure, respectively, which increased with age, to 32 and 44% for over 50 years. 11% reported tobacco consumption; 5.5%, high alcohol consumption; 40%, inadequate physical activity and 81%, inappropriate diet consumption. These correlated strongly with elderly age and poor education. The public facilities lacked diagnostics and specialist services; care in the private sector was expensive. Qualitative data revealed fears and cultural myths that affected treatment adherence. The results informed intervention design across the NCD care continuum. CONCLUSIONS: The study provides tools and methodology to gather evidence in designing comprehensive NCD programmes in low and middle income settings. The study also provides important insights into public-private partnership driving effective NCD care at primary care level.


Assuntos
Diabetes Mellitus/prevenção & controle , Promoção da Saúde/organização & administração , Hipertensão/prevenção & controle , Doenças não Transmissíveis/prevenção & controle , Atenção Primária à Saúde/organização & administração , Adulto , Idoso , Continuidade da Assistência ao Paciente , Estudos Transversais , Assistência à Saúde/organização & administração , Diabetes Mellitus/epidemiologia , Feminino , Grupos Focais , Humanos , Hipertensão/epidemiologia , Índia , Masculino , Pessoa de Meia-Idade , Doenças não Transmissíveis/epidemiologia , Setor Privado , Avaliação de Programas e Projetos de Saúde
7.
Public Health Nurs ; 36(3): 310-320, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30868661

RESUMO

OBJECTIVE: To provide a comprehensive evaluation of a grant-funded pilot diabetes care program. Rural adult patients living with poorly controlled diabetes were targeted for care. DESIGN AND SAMPLE: Retrospective study using a purposive sample of patients at select primary care sites with a glycated hemoglobin (A1C) greater than 8%. Interventions included nurse care management, telemedicine endocrinology consults, as well as diabetes self-management education (DSME), to enhance disease management and prevention of complications. MEASURES: Pre/post labs, DSME test scores, hospital claims data, satisfaction surveys, and a focus group were evaluated. RESULTS: Fifty-nine adults, 21-76 years of age, participated. Interventions demonstrated statistically significant reduction in A1C (10.10 vs. 9.27; p value = 0.002); DSME test score improvement (76.23 vs. 96.04; p < 0.05) and reduced hospital utilization (Emergency Department use 0.86 vs. 0.40; p value = 0.04; inpatient admissions 0.09 vs. 0.02; p value = 0.02). Patients and providers indicated strong satisfaction with the program components. Less hospital utilization reduced emergency department costs by 51.4% and inpatient costs by 96%. A rural community advisory network indicated satisfaction in delivery of program activities and outcome measures. CONCLUSIONS: This rural model shows potential for improving diabetes control, access to specialty care through telemedicine, and reduction of health care utilization costs.


Assuntos
Diabetes Mellitus/prevenção & controle , Educação de Pacientes como Assunto , Atenção Primária à Saúde/organização & administração , Serviços de Saúde Rural/organização & administração , Telemedicina , Adulto , Idoso , Feminino , Hemoglobina A Glicada/análise , Hospitalização , Humanos , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Avaliação de Programas e Projetos de Saúde , Estudos Retrospectivos , População Rural/estatística & dados numéricos , Adulto Jovem
8.
Phytomedicine ; 58: 152871, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30851580

RESUMO

BACKGROUND: Salvia miltiorrhiza (SM), one of the frequently used herbs in traditional Chinese medicine (TCM), has now attracted rising interests for a possible alternative in the management of diabetes. This review is aimed to providing a comprehensive perspective of SM in phytochemical constituents, pharmacological activities against diabetes and its complications, and safety. METHODS: A comprehensive search of published literatures was conducted to locate original publications pertaining to SM and diabetes till the end of 2017 using PubMed, China National Knowledge Infrastructure, National Science and Technology Library, China Science and Technology Journal Database, and Web of Science database. The main inquiry was used for the presence of the following keywords in various combinations in the titles and abstracts: Salvia miltiorrhiza, diabetes, obesity, phytochemistry, pharmacology, and safety. About 200 research papers and reviews were consulted. RESULTS: SM exhibited anti-diabetic activities by treating macro- and micro-vascular diseases in preclinical experiments and clinical trials through an improvement of redox homeostasis and inhibition of apoptosis and inflammation via the regulation of Wnt/ß-catenin, TSP-1/TGF-ß1/STAT3, JNK/PI3K/Akt, kinin B2 receptor-Akt-GSK-3ß, AMPKß/PGC-1α/Sirt3, Akt/AMPK, TXNIP/NLRP3, TGF-ß1/NF-κB, mineralocorticoid receptor/Na+/K+-ATPase, AGEs/RAGE, Nrf2/Keap1, CaMKKß/AMPK, AMPK/ACC, IRS-1/PI3K signaling pathways, and modulation of K+-Ca2+ channels, as well as influence of VEGF, NOS, AGEs, PPAR expression and hIAPP aggregation. The antidiabetic effects of this herb may be related to its TCM characters of improving blood circulation and reliving blood stasis. The main ingredients of SM included salvianolic acids and diterpenoid tanshinones, which have been well studied in the diabetic animals. Acute and subacute toxicity studies supported the notion that SM is well tolerated. CONCLUSION: SM may offer a new strategy for prevention and treatment of diabetes and its complications that stimulates extensive research into identifying potential anti-diabetic compounds and fractions as well as exploring the underlying mechanisms of this herb. Further scientific evidences are still required from well-designed preclinical experiments and clinical trials on its anti-diabetic effects and safety.


Assuntos
Diabetes Mellitus/tratamento farmacológico , Hipoglicemiantes/farmacologia , Medicina Tradicional Chinesa , Compostos Fitoquímicos/farmacologia , Salvia miltiorrhiza/química , Diabetes Mellitus/prevenção & controle , Humanos , Plantas Medicinais
9.
Int J Equity Health ; 18(1): 38, 2019 02 28.
Artigo em Inglês | MEDLINE | ID: mdl-30819193

RESUMO

BACKGROUND: The prevalence of hypertension and diabetes are expected to increase in sub-Saharan Africa over the next decade. Some studies have documented that lifestyle factors and lack of awareness are directly influencing the control of these diseases. Yet, few studies have attempted to understand the barriers to control of these conditions in rural settings. The main objective of this study was to understand the challenges to hypertension and diabetes care in rural Uganda. METHODS: We conducted semi-structured interviews with 24 patients with hypertension and/or diabetes, 11 health care professionals (HCPs), and 12 community health workers (known as village health team members [VHTs]) in Nakaseke District, Uganda. Data were coded using NVivo software and analyzed using a thematic approach. RESULTS: The results replicated several findings from other settings, and identified some previously undocumented challenges including patients' knowledge gaps regarding the preventable aspects of HTN and DM, patients' mistrust in the Ugandan health care system rather than in individual HCPs, and skepticism from both HCPs and patients regarding a potential role for VHTs in HTN and DM management. CONCLUSIONS: In order to improve hypertension and diabetes management in this setting, we recommend taking actions to help patients to understand NCDs as preventable, for HCPs and patients to advocate together for health system reform regarding medication accessibility, and for promoting education, screening, and monitoring activities to be conducted on a community level in collaboration with village health team members.


Assuntos
Diabetes Mellitus/prevenção & controle , Acesso aos Serviços de Saúde , Hipertensão/prevenção & controle , Serviços de Saúde Rural/organização & administração , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Atitude do Pessoal de Saúde , Atitude Frente a Saúde , Agentes Comunitários de Saúde/psicologia , Agentes Comunitários de Saúde/estatística & dados numéricos , Diabetes Mellitus/epidemiologia , Feminino , Pessoal de Saúde/psicologia , Pessoal de Saúde/estatística & dados numéricos , Humanos , Hipertensão/epidemiologia , Masculino , Pessoa de Meia-Idade , Pacientes/psicologia , Pacientes/estatística & dados numéricos , Pesquisa Qualitativa , Uganda/epidemiologia , Adulto Jovem
10.
Pregnancy Hypertens ; 15: 98-107, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30825935

RESUMO

OBJECTIVES: To evaluate the feasibility and effectiveness of a postpartum lifestyle intervention after pregnancies complicated by preeclampsia, fetal growth restriction (FGR) and/or gestational diabetes mellitus (GDM) to improve maternal risk factors for future cardiometabolic disease. METHODS: Women following a complicated pregnancy were included six months postpartum in this specific pre-post controlled designed study. It has been conducted in one tertiary and three secondary care hospitals (intervention group) and one secondary care hospital (control group). The program consisted of a computer-tailored health education program combined with three individual counselling sessions during seven months. Primary outcome measures were the proportion of eligible women and weight change during the intervention. RESULTS: Two hundred and six women were willing to participate. The proportion of eligible women who complied with the intervention was 23%. Major barrier was lack of time. Adjusted weight change attributed to lifestyle intervention was -1.9 kg (95%-CI -4.3 to -0.3). Further changes were BMI (-0.9 kg/m2 (95%-CI -1.4 to -0.3)), waist-to-hip ratio (-0.04 cm/cm (95%-CI -0.06 to -0.03)), blood pressure medication use (19% (95%-CI 9% to 28%)), HOMA2-score (59 %S (95%-CI 18 to 99)) and total fat intake (-2.9 gr (95%-CI -4.6 to -1.2)). CONCLUSIONS: The results support feasibility and effectiveness of a lifestyle intervention after complicated pregnancies to improve maternal cardiometabolic risk factors. Further randomized controlled studies are needed with longer follow-up to evaluate durability. In the meantime, we suggest health care professionals to offer lifestyle interventions to women after complicated pregnancies.


Assuntos
Doenças Cardiovasculares/prevenção & controle , Diabetes Mellitus/prevenção & controle , Estilo de Vida Saudável , Período Pós-Parto , Diabetes Gestacional/terapia , Estudos de Viabilidade , Feminino , Retardo do Crescimento Fetal/terapia , Humanos , Ensaios Clínicos Controlados não Aleatórios como Assunto , Cuidado Pós-Natal/métodos , Pré-Eclâmpsia/terapia , Gravidez , Fatores de Risco
11.
Bull World Health Organ ; 97(2): 154-159, 2019 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-30728621

RESUMO

Problem: Both sugar-sweetened beverage consumption and the incidence of obesity have increased in the Philippines in recent years. Approach: A proposal to tax sugar-sweetened beverages was introduced in the House of Representatives and merged into a proposed comprehensive Tax Reform for Acceleration and Inclusion (TRAIN) Bill to increase the likelihood of acceptance. The health department and finance department recommended a policy that would maximize benefits to both public health and government revenue. To advance discussions, the health department expanded the health argument to include the country's poor performance in oral health. The approved TRAIN Law adopted the term sweetened beverage to emphasize that the tax covers both sugar and non-sugar sweetened beverages. The tax rate was set to 6.00 Philippine pesos (0.111 United States dollars) per litre of sweetened beverages. The sugar industry successfully lobbied for higher tax rates on beverages containing high-fructose corn syrup, resulting in a differential rate of 12.00 Philippine pesos per litre. Local setting: Despite a 12% value-added tax on sugar-sweetened beverages, sales had been sustained by enhanced marketing and product variants being offered in small portions. Relevant changes: One month after implementation of the tax in 1 January 2018, prices of taxable sweetened beverages had increased by 16.6 to 20.6% and sales in sari-sari (convenience) stores had declined 8.7%. Lessons learnt: The tax benefited from high-level government commitment and support, keeping policy simple reduced opportunities for tax avoidance and evasion, and taking both health and non-health considerations into account were helpful in arguing for the tax.


Assuntos
Bebidas/economia , Política de Saúde/economia , Edulcorantes/economia , Impostos , Diabetes Mellitus/prevenção & controle , Política de Saúde/legislação & jurisprudência , Promoção da Saúde/economia , Promoção da Saúde/métodos , Humanos , Obesidade/prevenção & controle , Filipinas , Avaliação de Programas e Projetos de Saúde , Açúcares/economia , Impostos/legislação & jurisprudência , Organização Mundial da Saúde
12.
Stud Health Technol Inform ; 257: 455-459, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30741239

RESUMO

In this study, a mobile cloud healthcare system was implemented to assist middle- and old-aged people with diabetes preventive healthcare. First of all, a prototype system was developed. It was a system relying on data mining computing technology and big data analytics. Besides, it was constructed under the environment architecture of VMware cloud computing. This mobile cloud healthcare system was developed via mobile devices. Its purpose was to set up a diabetes preventive healthcare service for users, and to further assess the usability of this mobile cloud care system.


Assuntos
Computação em Nuvem , Mineração de Dados , Assistência à Saúde , Diabetes Mellitus , Idoso , Diabetes Mellitus/prevenção & controle , Humanos , Pessoa de Meia-Idade
14.
Crit Care Nurs Clin North Am ; 31(1): 39-47, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30736934

RESUMO

There is a need to educate minority women on prevention and management of risk factors that lead to cardiovascular disease (CVD0. Black women have the highest prevalence of CVD. Hypertension, diabetes, overweight/obesity, smoking, and hyperlipidemia have shown some correlation to the prevalence of CVD among minorities. Therefore, implementing strategies to increase awareness, and to prevent and manage CVD risk factors is vital.


Assuntos
Afro-Americanos/estatística & dados numéricos , Doenças Cardiovasculares/epidemiologia , Grupos Minoritários , Educação de Pacientes como Assunto , Doenças Cardiovasculares/etnologia , Diabetes Mellitus/prevenção & controle , Feminino , Disparidades em Assistência à Saúde , Humanos , Hipertensão/prevenção & controle , Grupos Minoritários/estatística & dados numéricos , Obesidade/prevenção & controle , Prevalência , Fatores de Risco , Fatores Socioeconômicos
16.
Nutrients ; 11(1)2019 Jan 14.
Artigo em Inglês | MEDLINE | ID: mdl-30646548

RESUMO

Honey, a natural sweetener has been used universally as a complete food and in complementary medicine since early antiquity. Honey contains over 180 substances, including sugars mainly fructose and glucose, water and a plethora of minor constituents such as vitamins, minerals and phytochemicals. The chemical composition of honey varies depending on floral origin, environment and geographical conditions. The sugar components dominate honey composition and they are accountable for sensory and physicochemical properties in food industry. Although present in small quantities, non-sugar components are the major contributors to the health benefits of honey. Our review summarizes and discusses composition of honey, its protective effects and possible action modes on risk factors of atherosclerosis.


Assuntos
Aterosclerose/prevenção & controle , Mel/análise , Antioxidantes/análise , Diabetes Mellitus/prevenção & controle , Açúcares da Dieta/análise , Frutose/análise , Glucose/análise , Mel/efeitos adversos , Humanos , Hipertensão/prevenção & controle , Estresse Oxidativo , Fatores de Risco , Oligoelementos/análise , Vitaminas/análise
17.
Yakugaku Zasshi ; 139(1): 41-45, 2019.
Artigo em Japonês | MEDLINE | ID: mdl-30606927

RESUMO

The destruction of ß cells of pancreatic islets results in a reduced level of insulin secretion, thus resulting in the onset of diabetes. Diabetes caused by such a decrease in insulin secretion has been reported to be associated with mitochondrial dysfunction. Because of this, mitochondrial therapy would be expected to be a useful and productive strategy for the treatment of this disease. We previously reported the development of a MITO-Porter, a liposome-based nanocarrier that permits macromolecular cargos to be delivered into mitochondria via membrane fusion. In this presentation, we present our current findings on the development of a mitochondrial nanocarrier system aimed at the development of a novel method for treating and preventing diabetes. The system includes "a nanocarrier system for nucleic acids targeted to pancreatic ß cells", and "an in vivo system for the delivery of nucleic acids targeting the pancreas". In this presentation, we propose the use of a "mitochondrial nanocarrier system" as a novel method for the treatment and prevention of diabetes, and discuss the contribution of mitochondrial nanocarrier systems to innovative drug development.


Assuntos
Sistemas de Liberação de Medicamentos , Células Secretoras de Insulina , Mitocôndrias , Nanocápsulas , Ácidos Nucleicos/administração & dosagem , Animais , Diabetes Mellitus/tratamento farmacológico , Diabetes Mellitus/prevenção & controle , Humanos , Secreção de Insulina , Células Secretoras de Insulina/ultraestrutura , Camundongos
18.
J Med Food ; 22(2): 178-185, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30657431

RESUMO

Pleurotus eryngii var. ferulae (PEF) is traditionally used in the prevention and treatment of lifestyle-related diseases. In this study, we investigated the ability of PEF extract to prevent obesity and metabolic diseases and explored the underlying mechanism. Mice were fed a high-fat diet (HFD) containing PEF extract for 12 weeks, and their body weight, adipose tissue and liver weights, and lipid profiles and blood glucose levels, were monitored. Fecal triglyceride (TG) levels were also measured and olive oil-loading tests were performed. Furthermore, the effect of PEF extract on pancreatic lipase (PL) activity was examined in vitro. Treatment with PEF extract for 12 weeks resulted in a significant decrease in the HFD-induced increases in body weight, white adipose tissue weight, liver weights, and lipid profiles, and improved glucose tolerance and insulin sensitivity. To assess the mechanism underlying the effect of PEF extract on obesity and diabetes, we investigated its role in inhibiting lipid absorption. Consumption of an HFD containing PEF extract significantly increased the TG level in feces compared with the controls, suggesting inhibition of TG absorption in the digestive tract. Furthermore, PEF extract suppressed the increase in serum TG levels resulting from oral administration of a lipid emulsion to mice, confirming inhibition of TG absorption. Moreover, PEF extract inhibited PL activity in vitro. Our combined results indicate that the anti-obesity and antidiabetic effect of PEF extract in mice fed an HFD may be caused by inhibition of lipid absorption as a result of reduced PL activity.


Assuntos
Dieta Hiperlipídica/efeitos adversos , Lipase/antagonistas & inibidores , Metabolismo dos Lipídeos/efeitos dos fármacos , Obesidade/metabolismo , Pâncreas/enzimologia , Extratos Vegetais/farmacologia , Pleurotus , Tecido Adiposo Branco/metabolismo , Animais , Fármacos Antiobesidade/farmacologia , Fármacos Antiobesidade/uso terapêutico , Glicemia/metabolismo , Peso Corporal/efeitos dos fármacos , Diabetes Mellitus/metabolismo , Diabetes Mellitus/prevenção & controle , Gorduras na Dieta/administração & dosagem , Gorduras na Dieta/efeitos adversos , Gorduras na Dieta/metabolismo , Fezes , Trato Gastrointestinal/efeitos dos fármacos , Trato Gastrointestinal/metabolismo , Resistência à Insulina , Absorção Intestinal/efeitos dos fármacos , Lipídeos/administração & dosagem , Lipídeos/sangue , Fígado/efeitos dos fármacos , Masculino , Camundongos Endogâmicos C57BL , Obesidade/etiologia , Obesidade/prevenção & controle , Fitoterapia , Extratos Vegetais/uso terapêutico , Triglicerídeos/sangue , Triglicerídeos/metabolismo
19.
Diabetes Metab Syndr ; 13(1): 5-7, 2019 Jan - Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30641753

RESUMO

A panel of expert diabetologist clinicians developed consensus standards to address the quality gaps inclinic point of care testing (PoCT) especially pertaining to diabetes care and management in India. The following summarized principles were established- 1. PoCT definition, 2. Advantages and critical aspects of PoCT including guideline recommendations and accreditations, analytical factors (pre &post analytical included) and consensus reached for an ideal PoC analyzer and 3. Key recommendations on in-clinic PoCT implementation by the panel. The experts suggested next steps that included key comparative (PoCT vs NGSP accredited lab) and patient benefit studies on PoCT.


Assuntos
Biomarcadores/análise , Diabetes Mellitus/prevenção & controle , Testes Imediatos , Guias de Prática Clínica como Assunto/normas , Padrões de Prática Médica/normas , Glicemia/análise , Gerenciamento Clínico , Hemoglobina A Glicada/análise , Humanos , Prognóstico , Medição de Risco
20.
Food Chem ; 271: 362-371, 2019 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-30236688

RESUMO

The current review was aimed to summarize the nutritional values and various health benefits of fermented soy products. Several previous researches proved that soy products rich in protein can reduce the serum concentrations of total cholesterol, low-density lipoproteins (LDLs), and triglycerides if consumed instead of animal protein. Apart from these lipid-lowering effects, fermented soy products also proved to be effective in attenuating the effects of diabetes mellitus, blood pressure, cardiac disorders and cancer-related issues. The nutritional value of the fermented soy products gains much attention due to its increased levels compared to the non-fermented ones. The origin, compositions, nutritional values of different fermented soy products and health-promoting benefits of fermented soy products were systematically reviewed. Hence the in-depth analysis of the various research findings on fermented soy products, beneficial activities may help the future researchers to derive a conclusion on its beneficial effects on health.


Assuntos
Diabetes Mellitus/prevenção & controle , Valor Nutritivo , Soja , Animais , Fermentação , Humanos , Proteínas de Soja , Triglicerídeos
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