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1.
Ned Tijdschr Geneeskd ; 1642020 11 05.
Artigo em Holandês | MEDLINE | ID: mdl-33331733

RESUMO

Because of COVID-19 outbreak people wash more often their hands and use more often and longer disposable gloves. The natural skin barrier function is damaged by washing hand or using disinfectants, because of this allergic and irritative hand eczema develops. Allergic hand eczema can be caused by materials which people work with, and by ingredients of creme and soap, but also by wearing gloves. To prevent hand eczema, good protection of the hands is essential. It is very important to have knowledge about different gloves to inform (health) worker about wearing gloves in the proper way.


Assuntos
Eczema , Luvas Protetoras , Desinfecção das Mãos/métodos , Higienizadores de Mão/efeitos adversos , Prevenção Primária/métodos , Sabões/efeitos adversos , /epidemiologia , Eczema/etiologia , Eczema/prevenção & controle , Luvas Protetoras/efeitos adversos , Luvas Protetoras/classificação , Mãos , Humanos , Inquéritos e Questionários
2.
Clin Dermatol ; 38(4): 477-483, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32972606

RESUMO

Biotinidase deficiency is a rare hereditary metabolic disease. Only a few cases have been reported in China, almost all of which have been in the pediatric population. We report a case of a girl with characteristic skin and hair findings with a negative family history, although her grandparents were consanguineous. The metabolites in the proband's blood and urine increased prominently, and the percentage of biotinase was 1.168%, much lower than normal. Genotyping identified two heterozygous mutations, which were C.1457T>A (p.L486Q) and C.1491dupT (p.L498Ffs*13) in the BTD gene. The diagnosis of biotinidase deficiency was established. No relevant reports about the missense mutation at the mutation site C.1457T>A (p.L486Q) of the BTD gene have been retrieved. Biotin replacement therapy was administered in the dose of 20 mg/d. The dermatitis subsided after 1 month, and the hair color was almost normal after 3 months. This reminds dermatologists to include biotinidase deficiency in their clinical differential when faced with children's intractable dermatitis, yellow hair, and alopecia.


Assuntos
Alopecia/etiologia , Biotina/administração & dosagem , Biotina/metabolismo , Deficiência de Biotinidase/complicações , Deficiência de Biotinidase/diagnóstico , Deficiência de Biotinidase/genética , Biotinidase/genética , Eczema/etiologia , Cor de Cabelo , Deficiência de Biotinidase/tratamento farmacológico , Criança , Feminino , Heterozigoto , Humanos , Mutação , Resultado do Tratamento
5.
Medicine (Baltimore) ; 99(21): e20327, 2020 May 22.
Artigo em Inglês | MEDLINE | ID: mdl-32481318

RESUMO

BACKGROUND: Eczema is a relapsing and persistent inflammatory skin disease affecting about one-fifth of children worldwide. As in other developed countries, the prevalence of this chronic disease in Hong Kong is approximately 30%. Moreover, the number of local cases reported has been on a rising trend since 1995. Eczema frequently starts in early infancy. A total of 45% of all cases begin within the first six months of life, 60% during the first year and 85% before the age of 5. The pathophysiology of eczema is multi-factorial and is a complex inter-relationship between skin barrier, genetic predisposition, immunologic development, microbiome, environment, nutrition, and pharmacological and psychological factors. OBJECTIVE: To characterize the longitudinal changes of gut microbial profile in early childhood and to examine the association between gut microbiome diversity, environmental factors and the development of eczema in early childhood. METHOD: We will conduct a longitudinal cohort study that follows 1250 Hong Kong Chinese infants for 2 years and assess the gut microbiome and other potential environmental factors in the aetiology of eczema. Parents will be asked to provide demographic data, their infant birth data, allergy condition, diet, environmental conditions as well as the data on maternal stress. Stool specimen will be collected for gut microbiome diversity analysis. We will examine newborn infants at enrollment, at 4 months, 1 year and 2 years after birth. EXPECTED RESULTS: This study will evaluate the association between gut microbiome, environmental factors and the development of eczema in Chinese infants. Findings from this study may be used to develop a predictive path model to guide effective health promotion, disease prevention and management.


Assuntos
Eczema/etiologia , Microbioma Gastrointestinal/fisiologia , Pré-Escolar , Eczema/epidemiologia , Eczema/microbiologia , Feminino , Seguimentos , Hong Kong/epidemiologia , Humanos , Incidência , Lactente , Recém-Nascido , Masculino , Estudos Prospectivos , Fatores de Tempo
6.
BMC Infect Dis ; 20(1): 312, 2020 Apr 28.
Artigo em Inglês | MEDLINE | ID: mdl-32345218

RESUMO

BACKGROUND: While there is increasing knowledge about the gut microbiome, the factors influencing and the significance of the gut resistome are still not well understood. Infant gut commensals risk transferring multidrug-resistant antibiotic resistance genes (ARGs) to pathogenic bacteria. The rapid spread of multidrug-resistant pathogenic bacteria is a worldwide public health concern. Better understanding of the naïve infant gut resistome may build the evidence base for antimicrobial stewardship in both humans and in the food industry. Given the high carriage rate of extended spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in Asia, we aimed to evaluate community prevalence, dynamics, and longitudinal changes in antibiotic resistance gene (ARG) profiles and prevalence of ESBL-producing E. coli and K. pneumoniae in the intestinal microbiome of infants participating in the Growing Up in Singapore Towards Healthy Outcomes (GUSTO) study, a longitudinal cohort study of pregnant women and their infants. METHODS: We analysed ARGs in the first year of life among 75 infants at risk of eczema who had stool samples collected at multiple timepoints using metagenomics. RESULTS: The mean number of ARGs per infant increased with age. The most common ARGs identified confer resistance to aminoglycoside, beta-lactam, macrolide and tetracycline antibiotics; all infants harboured these antibiotic resistance genes at some point in the first year of life. Few ARGs persisted throughout the first year of life. Beta-lactam resistant Escherichia coli and Klebsiella pneumoniae were detected in 4 (5.3%) and 32 (42.7%) of subjects respectively. CONCLUSION: In this longitudinal cohort study of infants living in a region with high endemic antibacterial resistance, we demonstrate that majority of the infants harboured several antibiotic resistance genes in their gut and showed that the infant gut resistome is diverse and dynamic over the first year of life.


Assuntos
Antibacterianos/farmacologia , Farmacorresistência Bacteriana/genética , Eczema/diagnóstico , Microbioma Gastrointestinal/efeitos dos fármacos , Aminoglicosídeos/farmacologia , Proteínas de Bactérias/genética , Proteínas de Bactérias/metabolismo , Eczema/etiologia , Escherichia coli/efeitos dos fármacos , Escherichia coli/enzimologia , Escherichia coli/isolamento & purificação , Fezes/microbiologia , Feminino , Humanos , Lactente , Recém-Nascido , Klebsiella pneumoniae/efeitos dos fármacos , Klebsiella pneumoniae/enzimologia , Klebsiella pneumoniae/isolamento & purificação , Estudos Longitudinais , Masculino , Risco , beta-Lactamases/genética , beta-Lactamases/metabolismo , beta-Lactamas/farmacologia
7.
PLoS One ; 15(4): e0231784, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32298373

RESUMO

BACKGROUND: Night shift work surrounding pregnancy may contribute to the risk of developing atopic diseases in offspring due to alterations in the prenatal environment, from stress. OBJECTIVE: To examine the association of maternal night shift work surrounding pregnancy and offspring risk of developing atopic diseases from childhood to adolescence. METHODS: We examined the association between night shift work before and during pregnancy among 4,044 mothers in the Nurses' Health Study II (NHSII) and atopic dermatitis, asthma and hay fever risk in 4,813 of their offspring enrolled in the Growing Up Today Study (GUTS). Mothers reported whether GUTS participants had ever been diagnosed with atopic dermatitis, asthma or hay fever in the GUTS Mothers' questionnaire. Generalized estimating equation regression models were used to estimate multivariable adjusted odds ratios (OR) and 95% confidence intervals (CIs). RESULTS: There were no significant associations between pre-conception maternal night shift work and risk of atopic dermatitis, asthma or hay fever in their offspring. Among 545 mothers with information on night shift work during pregnancy, shift work also was not associated with atopic dermatitis, asthma or hay fever in the offspring. Stratified analyses by history of parental atopy and maternal chronotype showed some statistically significant findings, but they were inconsistent and no significant interaction was seen with increasing duration of night shift work. CONCLUSION: In this study, night shift work before and during pregnancy did not increase offspring risk of developing atopic dermatitis, asthma or hay fever.


Assuntos
Asma/epidemiologia , Dermatite Atópica/epidemiologia , Efeitos Tardios da Exposição Pré-Natal , Rinite Alérgica Sazonal/epidemiologia , Jornada de Trabalho em Turnos/efeitos adversos , Adulto , Criança , Estudos de Coortes , Eczema/etiologia , Estudos Epidemiológicos , Feminino , Humanos , Masculino , Mães , Razão de Chances , Gravidez , Fatores de Risco , Jornada de Trabalho em Turnos/estatística & dados numéricos , Inquéritos e Questionários
10.
Ann Dermatol Venereol ; 147(2): 131-134, 2020 Feb.
Artigo em Francês | MEDLINE | ID: mdl-31973905

RESUMO

BACKGROUND: Severe combined immunodeficiency (SCID) is a the most severe form of primary immunodeficiency and is highly heterogeneous. We report an atypical form of SCID revealed by exfoliative erythroderma. PATIENTS AND METHODS: A 3-month-old boy, born to consanguineous parents, was admitted to the dermatology department with exfoliative erythroderma associated with eczematous patches and alopecia of the scalp, eyelashes, and eyebrows, but with no lymphadenopathy or hepatosplenomegaly. He displayed chronic diarrhea and recurrent infection since birth. A complete blood count showed marked leukocytosis with eosinophilia and lymphocytosis. These clinical and biological findings improved partly with topical steroids. The patient no longer had erythroderma and showed regrowth of hair, eyelashes and eyebrows. The subsequent CBC showed less marked eosinophilia with mild lymphopenia and no leukocytosis. Immunoglobulin levels were undetectable. Primary immunodeficiency was discussed. Immunological investigations concluded on a diagnosis of T-B-NK+ SCID. Mutation analysis revealed a homozygous c.1338C>G (pCys446Trp) mutation in the RAG2 gene. Hematopoietic stem cell transplantation is planned in the near future. CONCLUSION: This case illustrates atypical T-B-NK+ SCID revealed by severe exfoliative erythroderma in a 3-month-old boy with RAG2 gene mutation. Neonatal erythroderma must be considered a warning sign of primary immunodeficiency requiring immediate immunological phenotyping as well as genetic testing for a definitive diagnosis.


Assuntos
Dermatite Esfoliativa/etiologia , Imunodeficiência Combinada Severa/complicações , Alopecia/etiologia , Alopecia/patologia , Doença Crônica , Consanguinidade , Proteínas de Ligação a DNA/genética , Dermatite Esfoliativa/patologia , Diarreia/etiologia , Eczema/etiologia , Eczema/patologia , Transplante de Células-Tronco Hematopoéticas , Humanos , Lactente , Masculino , Proteínas Nucleares/genética , Fotografação , Imunodeficiência Combinada Severa/genética , Imunodeficiência Combinada Severa/terapia
11.
Medicine (Baltimore) ; 98(45): e17914, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31702670

RESUMO

There are very few reports of eczema and other prosthetic-related allergic skin complications following arthroplasty. We aimed to assess the risk of eczema after joint replacement.We performed a retrospective population-based cohort study in 2024 joint replacement patients using the Longitudinal Health Insurance Database. For comparison, 8096 controls were selected, with 4 control subjects for each joint replacement patient matched for age, sex, and index year, to assess eczema risk. We examined 14-year cumulative eczema incidence associated with age, sex, immunity, disease history, and joint replacement location.Eczema rates in the joint replacement patients were 38% higher than in the control group (57.90 vs 41.84 per 1000 person-years, respectively). Compared with the control group, joint replacement patients showed a 1.35-fold increased risk of eczema according to the multivariable Cox model (95% Confidence interval [CI] = 1.23-1.49). Knee replacement patients had higher eczema risk compared with the control group (Hazard ratio [HR] = 1.45, 95% CI = 1.33-1.70). Stratified by study period, the joint replacement cohort had a higher eczema risk after the 3-month follow-up.Our study revealed that joint arthroplasty increased risk of eczema in this 14-year follow-up study, and this was not related to personal atopic history or gender.


Assuntos
Artroplastia de Substituição/efeitos adversos , Eczema/epidemiologia , Prótese Articular/efeitos adversos , Idoso , Artroplastia de Substituição/estatística & dados numéricos , Estudos de Casos e Controles , Comorbidade , Dermatite Alérgica de Contato/epidemiologia , Eczema/etiologia , Feminino , Humanos , Incidência , Estudos Longitudinais , Masculino , Metais/efeitos adversos , Pessoa de Meia-Idade , Modelos de Riscos Proporcionais , Estudos Retrospectivos , Fatores de Risco
12.
Int J Circumpolar Health ; 78(1): 1682421, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31638483

RESUMO

Persistent Organic Pollutants (POPs) are environmental chemicals bio-accumulating through the food chain. POPs can affect the foetal development of the immune, the neural and the reproductive system. POPs are endocrine disruptors and shown to interfere with child vaccination responses. Our hypothesis is that POPs interfere with the immune system increasing the risk of asthma, allergy and eczema. In a pilot cross-sectional study, we sent 120 questionnaires to Inuit mothers to elucidate the relation between smoking during pregnancy and the risk of child asthma, allergy and eczema, and the possible modifying effect of breastfeeding. Fifty-one mothers responded. We found that the risk of getting allergy among the offspring was higher when the mother had been smoking during pregnancy and the child being breastfed <12 months (OR = 5.67, 95% CI: 0.754; 42.58, p = 0.092). Furthermore, we found that children with eczema were predisposed of having asthma (OR = 19.6, 95% CI: 2.19; 176, p = 0.008), also allergy when breastfed >12 months (OR = 17.0, 95% CI: 1.02; 283, p = 0.048). Abbreviation: ACCEPT (Adaptation to Climate Change, Environmental Pollution, and Dietary Transition).


Assuntos
Asma/etiologia , Dieta/efeitos adversos , Eczema/etiologia , Hipersensibilidade/etiologia , Inuítes/estatística & dados numéricos , Estilo de Vida , Efeitos Tardios da Exposição Pré-Natal/epidemiologia , Asma/epidemiologia , Aleitamento Materno/efeitos adversos , Aleitamento Materno/estatística & dados numéricos , Pré-Escolar , Dieta/estatística & dados numéricos , Eczema/epidemiologia , Feminino , Groenlândia/epidemiologia , Humanos , Hipersensibilidade/epidemiologia , Gravidez , Efeitos Tardios da Exposição Pré-Natal/etiologia , Fatores de Risco , Fumar/efeitos adversos , Inquéritos e Questionários
14.
Immunol Allergy Clin North Am ; 39(4): 521-533, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31563186

RESUMO

Eczema is a chronic, relapsing, and remitting disease that can affect patients from infancy through adulthood. Severity of eczema ranges from mild to severe and can be plagued with recurrent flares. These flares can be difficult to treat and may require use of different strategies to address the issue. In this article, the author addresses different therapeutic options that can be used in those patients with difficult-to-treat eczema.


Assuntos
Eczema/diagnóstico , Eczema/etiologia , Eczema/terapia , Animais , Terapia Combinada , Testes Diagnósticos de Rotina , Gerenciamento Clínico , Eczema/prevenção & controle , Humanos , Avaliação de Resultados em Cuidados de Saúde , Avaliação de Sintomas
15.
BMJ Open ; 9(9): e033013, 2019 09 26.
Artigo em Inglês | MEDLINE | ID: mdl-31558464

RESUMO

INTRODUCTION: In the UK, about a quarter of women give birth by caesarean section (CS) and are offered prophylactic broad-spectrum antibiotics to reduce the risk of maternal postpartum infection. In 2011, national guidance was changed from recommending antibiotics after the umbilical cord was cut to giving antibiotics prior to skin incision based on evidence that earlier administration reduces maternal infectious morbidity. Although antibiotics cross the placenta, there are no known short-term harms to the baby. This study aims to address the research gap on longer term impact of these antibiotics on child health. METHODS AND ANALYSIS: A controlled interrupted time series study will use anonymised mother-baby linked routine electronic health records for children born during 2006-2018 recorded in UK primary care (The Health Improvement Network, THIN and Clinical Practice Research Datalink, CPRD) and secondary care (Hospital Episode Statistics, HES) databases. The primary outcomes of interest are asthma and eczema, two common allergy-related diseases in childhood. In-utero exposure to antibiotics immediately prior to CS will be compared with no exposure when given after cord clamping. The risk of outcomes in children delivered by CS will also be compared with a control cohort delivered vaginally to account for time effects. We will use all available data from THIN, CPRD and HES with estimated power of 80% and 90% to detect relative increase in risk of asthma of 16% and 18%, respectively at the 5% significance level. ETHICS AND DISSEMINATION: Ethical approval has been obtained from the University of Birmingham Ethical Review Committee with scientific approvals obtained from the independent scientific advisory committees from the Medicines and Healthcare products Regulatory Agency for CPRD and the data provider, IQVIA for THIN. The results will be published in peer-reviewed journals, presented at national and international conferences and disseminated to stakeholders.


Assuntos
Antibacterianos/farmacologia , Antibioticoprofilaxia/métodos , Cesárea/efeitos adversos , Saúde da Criança , Complicações Infecciosas na Gravidez/prevenção & controle , Infecção da Ferida Cirúrgica/prevenção & controle , Cordão Umbilical , Antibacterianos/efeitos adversos , Antibacterianos/uso terapêutico , Antibioticoprofilaxia/efeitos adversos , Asma/etiologia , Asma/prevenção & controle , Criança , Constrição , Bases de Dados Factuais , Eczema/etiologia , Eczema/prevenção & controle , Registros Eletrônicos de Saúde , Feminino , Humanos , Recém-Nascido , Análise de Séries Temporais Interrompida , Saúde Materna , Parto , Placenta , Gravidez , Projetos de Pesquisa , Infecção da Ferida Cirúrgica/etiologia , Reino Unido
17.
BMC Pediatr ; 19(1): 239, 2019 07 17.
Artigo em Inglês | MEDLINE | ID: mdl-31315604

RESUMO

BACKGROUND: Few prospective birth cohort studies are available on the effects of prenatal and early-life exposures on food allergy and eczema among Chinese children. The aim of this study was to evaluate the influence of prenatal and early-life exposures on food allergy and eczema during the first year of life in a prospective birth cohort study. METHODS: This study was based on a prospective, observational birth cohort of 976 mother-child pairs in three Streets in Changsha, China from January to December 2015. Data on prenatal, early-life exposures and allergic outcomes were obtained from questionnaires collected at birth, and 1, 3, 6, 8, and 12 months of age. Multivariate logistic regression models were performed to estimate the effects of prenatal and early-life exposures on food allergy and eczema. RESULTS: Common risk factors for food allergy and eczema in infancy were parental history of allergy, while moderate eggs consumption (3-4 times/week) during pregnancy was protective for both of them compared with low consumption (≤ 2 times/week). Factors only associated with food allergy were maternal aquatic products consumption during pregnancy, number of older siblings and age of solid food introduction, whereas factors only associated with eczema were maternal milk or milk products consumption during pregnancy, maternal antibiotic exposure during pregnancy, season of birth and antibiotic exposure through medication during the first year of life. CONCLUSION: Our study suggests that factors associated with food allergy and eczema are multifaceted, which involving hereditary, environmental and nutritional exposures. Furthermore, differential factors influence the development of food allergy and eczema in infants.


Assuntos
Eczema/etiologia , Exposição Ambiental , Hipersensibilidade Alimentar/etiologia , Efeitos Tardios da Exposição Pré-Natal , Adulto , Alérgenos/efeitos adversos , China/epidemiologia , Parto Obstétrico , Dieta , Eczema/epidemiologia , Ovos/efeitos adversos , Feminino , Hipersensibilidade Alimentar/epidemiologia , Humanos , Lactente , Alimentos Infantis , Recém-Nascido , Masculino , Idade Materna , Hipersensibilidade a Leite/epidemiologia , Hipersensibilidade a Leite/etiologia , Gravidez , Estudos Prospectivos , Fatores de Risco , Alimentos Marinhos/efeitos adversos , Irmãos , Adulto Jovem
18.
Indoor Air ; 29(5): 748-760, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31295372

RESUMO

We surveyed 40 010 three- to six-year-old children in seven Chinese cities (Beijing, Taiyuan, Urumqi, Shanghai, Nanjing, Changsha, and Chongqing) during 2010-2012 so as to investigate possible links between home renovation and childhood eczema. Their parents responded to questions on home renovation and childhood eczema. Multivariate and two-level (city-child) logistic regression analyses yielding odds ratios with 95% confidence intervals were performed. Sensitivity analyses stratifying data for region, climate, and income level were also performed. The prevalences of childhood eczema in children with different floor and wall covering materials were significantly different and were significantly higher with home renovation during early lifetime. Exposure to synthetic materials significantly increased the risk of childhood eczema by 20%-25%. The risks (AOR, 95% CI) of current eczema among children in families with solid wood flooring and oil paint wall covering were 1.25 (1.04-1.49) and 1.35 (1.14-1.60), respectively. Home renovation during pregnancy was related to children's lifetime and current eczema.


Assuntos
Poluição do Ar em Ambientes Fechados/efeitos adversos , Materiais de Construção/efeitos adversos , Eczema/epidemiologia , Eczema/etiologia , Adulto , Criança , Pré-Escolar , China/epidemiologia , Cidades , Estudos Transversais , Exposição Ambiental , Feminino , Pisos e Cobertura de Pisos , Habitação , Humanos , Modelos Logísticos , Masculino , Pintura/efeitos adversos , Gravidez , Efeitos Tardios da Exposição Pré-Natal/etiologia , Prevalência , Fatores de Risco , Inquéritos e Questionários
19.
Environ Int ; 130: 104910, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31226554

RESUMO

The main aim was to study associations between asthma, allergic rhinitis and eczema among adults across China and dampness and mold at home. Young adults (N = 40,279) in eight cities in China answered a questionnaire in 2010-2012 (response rate 75.0%). Data on asthma, allergic rhinitis, eczema and the home environment was assessed by the questionnaire. Climate data was obtained from China Meteorological Administration and the website of Weather Underground. Health associations were analyzed by two-level logistic regression models, adjusting for covariates. Totally 1.6% had asthma, 6.6% allergic rhinitis and 2.2% eczema. Mold odor was associated with asthma (OR = 1.90) and allergic rhinitis (OR = 1.25-1.44). Window pane condensation in winter was associated with asthma (OR = 1.39), allergic rhinitis (OR = 1.26-1.58) and eczema (OR = 1.36-1.77). Presence of mold spots or damp stains was related to asthma (OR = 1.58-2.49), allergic rhinitis (OR = 1.35-1.76) and eczema (OR = 1.47-1.70). Water damage was related to asthma (OR = 1.69-1.82), allergic rhinitis (OR = 1.40-1.45) and eczema (OR = 1.44-1.96). Damp bed clothing was related to asthma (OR = 1.23), allergic rhinitis (OR = 1.23) and eczema (OR = 1.35). A higher dampness score was associated with increased odds ratios for diseases. Those living in older buildings had more asthma (OR = 1.39-1.76) and allergic rhinitis (OR = 1.16-1.21). Those living in suburban or rural areas had less asthma, allergic rhinitis and eczema as compared to those living in urban areas (OR values from 0.24 to 0.66). Stronger health associations with dampness and mold were found in southern China and in newer buildings (constructed after 2005). In conclusion, dampness and mold at home can be risk factors for asthma, allergic rhinitis and eczema among adults in China. Living in older buildings can be risk factors for asthma or allergic rhinitis while living in less urbanized areas can be protective.


Assuntos
Asma/epidemiologia , Eczema/epidemiologia , Fungos/isolamento & purificação , Umidade , Pais , Rinite Alérgica/epidemiologia , Adulto , Poluição do Ar em Ambientes Fechados/análise , Asma/etiologia , China/epidemiologia , Eczema/etiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Rinite Alérgica/etiologia , Fatores de Risco , Adulto Jovem
20.
Disaster Med Public Health Prep ; 13(5-6): 905-911, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31156072

RESUMO

OBJECTIVE: We aimed to investigate the association between types of housing and allergic symptoms at 3-4 years following the Great East Japan Earthquake. METHODS: Our study was based on the ToMMo Child Health Study conducted in 2014 and 2015, a cross-sectional survey of public school children in Miyagi Prefecture, Japan. Of the 46 648 invited schoolchildren in the 2nd to 8th grades, 9884 were included. Presence of eczema, wheezing, and mental health symptoms was defined with questionnaires. To calculate odds ratios (ORs) and 95% CIs for the associations between types of housing and eczema or respiratory symptoms, we fitted generalized linear mixed models, included a random effect for municipality of residence, and adjusted for sex, school grade, survey year, and mental health symptoms. RESULTS: Prefabricated temporary housing was significantly associated with eczema symptoms (OR, 1.46; 95% CI, 1.06-2.02). Even after adjusting for the presence of mental health symptoms, our analysis produced similar results (OR, 1.42; 95% CI, 1.03-1.96). Conversely, it was not significantly associated with respiratory symptoms (OR, 0.97; 95% CI, 0.61-1.54). CONCLUSIONS: Children living in prefabricated temporary housing had a higher prevalence of eczema symptoms; however, prevalence of respiratory symptoms was not significantly higher.


Assuntos
Eczema/etiologia , Habitação/classificação , Pneumopatias/etiologia , Adolescente , Criança , Estudos Transversais , Terremotos , Eczema/epidemiologia , Feminino , Acidente Nuclear de Fukushima , Nível de Saúde , Habitação/estatística & dados numéricos , Humanos , Japão/epidemiologia , Pneumopatias/epidemiologia , Masculino , Razão de Chances , Prevalência , Instituições Acadêmicas/organização & administração , Instituições Acadêmicas/estatística & dados numéricos , Inquéritos e Questionários
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