Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 4.653
Filtrar
1.
J Contemp Dent Pract ; 21(6): 657-665, 2020 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-33025935

RESUMO

AIM: The present study aimed to investigate the total number of visits required to conclude root canal treatments (RCTs) as well as the motivations associated to the choice of dentists practicing in low-income areas of Brazil. MATERIALS AND METHODS: A total of 3,103 questionnaires were electronically and individually delivered to professionals of Salvador, Sergipe, and Alagoas (Brazil). The questionnaire encompassed sociodemographic data and questions regarding the number of sessions required to conclude RCT. Also, postoperative pain, professional qualification, the use of technological resources, and time for one-visit treatment were evaluated. Data were analyzed using Chi-square and Poisson regression analyses (p < 0.05). RESULTS: A total of 326 responses were obtained with higher prevalence of specialists in the field of endodontics (36.8%). Dentists reported greater preference for rotary instrumentation (Alagoas 54.6%, Aracaju 62.1%, and Salvador 83.5%), and most of the participants reported multiple visits to treat root canals with the necrotic pulp tissue associated or not to periapical radiolucency, excluding Salvador (53.8%). Dentists who graduated in public dental schools were less likely to perform RCT of necrotic teeth with periapical lesion in one clinical appointment (p = 0.034). The single-session therapy was positively associated to continuing education attendance (p = 0.004) and to the occurrence of clinical complications (p < 0.001). Dentists who graduated in lato sensu programs were more likely to conclude RCT in less than 60 minutes (p < 0.001), although the occurrence of postoperative pain was more likely observed upon this scenario (p < 0.001). CONCLUSION: Despite the social inequalities in the analyzed area, professionals have been seeking for knowledge by means of continuing education programs and the implementation of technological resources in their clinical routine, although this fact has poorly influenced the acceleration of RCT. Clinical significances: The total number of visits to conclude endodontic treatment may be influenced by both professional and biological parameters such as the attendance to postgraduation programs and the use of technology as well as to the biological condition of the pulp and the occurrence of postoperative complications.


Assuntos
Endodontia , Tratamento do Canal Radicular , Brasil/epidemiologia , Assistência Odontológica , Necrose da Polpa Dentária , Humanos
2.
Braz Oral Res ; 34: e117, 2020 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-32901732

RESUMO

The aim of this study was to assess Brazilian endodontists' level of knowledge about the coronavirus disease (COVID-19) and examine its professional repercussions. The link to the online survey that was created for this study was shared with Brazilian endodontists through social networking applications. The questionnaire contained questions that pertained to COVID-19 and its impact on dental practice. The collected data were analyzed using t-test, chi-square analysis, and analysis of variance, and the level of significance was set at 0.05. A total of 2,135 participants responded to the questionnaire, and all five Brazilian regions were represented in the sample. A total of 98.50% of endodontists reported that dental procedures can transmit COVID-19. Complete social distancing was practiced by 96.68% of the participants, and approximately 25% knew someone who had COVID-19. Moreover, in their daily practice, 72.13% of them implemented biosecurity measures that are ineffective in preventing COVID-19. Furthermore, 91.7% of them reportedly suspended elective dental procedures. Only 55.69% of them reported that they performed only emergency procedures in their workplaces. Those who believed that COVID-19 cannot be transmitted during dental procedures were less knowledgeable about the symptoms of COVID-19 (p = 0.0095). Endodontists who believed that personal protective equipment cannot prevent contamination were more knowledgeable about the symptoms of COVID-19 than their counterparts (p = 0.0003). The participating Brazilian endodontists demonstrated adequate knowledge about the risk of contamination during dental procedures and the main symptoms of COVID-19. Only some professionals reported providing emergency dental care during the pandemic.


Assuntos
Infecções por Coronavirus/epidemiologia , Endodontistas , Conhecimentos, Atitudes e Prática em Saúde , Pneumonia Viral/epidemiologia , Betacoronavirus , Brasil , Infecções por Coronavirus/transmissão , Endodontia , Humanos , Pandemias , Pneumonia Viral/transmissão , Inquéritos e Questionários
3.
Eur J Paediatr Dent ; 21(3): 248-250, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32893661

RESUMO

Treatment of necrotic immature permanent anterior teeth with Portland cements apical plug. The long-term success of endodontic treatment depends on the quality of the apical and coronal seal. In necrotic immature teeth the treatment can be challenging for the clinician as the endodontic anatomy and the presence of bacterial infection need to be addressed with special techniques and materials in order to obtain an effective and biocompatible apical seal. Unfortunately, despite the best treatments, immature permanent teeth have a reduced resistance to fracture due to the arrest of root walls development.


Assuntos
Necrose da Polpa Dentária , Endodontia , Criança , Dentição Permanente , Humanos , Tratamento do Canal Radicular
4.
J Endod ; 46(9S): S105-S114, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32950182

RESUMO

INTRODUCTION: Regenerative endodontic therapy (RET) has gained considerable attention and wide approval. Although it is being performed routinely, the outcomes remain unpredictable, and the optimal approaches for treatment are not established. It has been shown that bacterial persistence in root canals in these cases significantly interferes with healing and root maturation. However, few objective clinical studies have evaluated the complex microflora present in the infections or the efficacy of various clinical procedures. In addition, the extent of the infection and biofilm maturation in immature teeth with necrotic pulp has been understudied. Furthermore, most models used in preclinical evaluation of these issues do not fully elucidate the complexity or variability of the clinical situation. RESULTS AND CONCLUSION: In this review, the main biological and clinical problems pertaining to RET will be discussed. Contemporary analysis of complex microbial communities will be reviewed with emphasis on how these types of analyses can provide clinically useful data. In addition, current and proposed approaches for the effective disinfection of the root canal environment without interference with stem cell viability or integrity of the dentin matrix in these cases will be explored. The future of research in this field, including better and more customizable approaches in RET, in light of recent technological advances and progress in endodontics, will be outlined.


Assuntos
Endodontia , Endodontia Regenerativa , Antibacterianos/uso terapêutico , Necrose da Polpa Dentária/tratamento farmacológico , Humanos , Regeneração , Tratamento do Canal Radicular
6.
Dental Press J Orthod ; 25(3): 20-29, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32844973

RESUMO

Endodontically treated teeth may be moved, as endodontic treatment is not a contraindication for orthodontic treatment. Apical periodontal repair begins when the periapical or pulp lesion has completely resolved. This may happen immediately after treatment if the filling material causes little or no irritation of periapical tissues, and particularly if the material is fully contained within the canal. When it leaks, a foreign body granuloma forms and persists for some months or indefinitely, depending on the composition of the filling material. Materials containing calcium hydroxide with no resin components undergo phagocytosis and disappear in some months, as macrophages gradually remove them. Materials containing resins, silicone, ionomers, zinc oxide-eugenol, bioceramics or gutta-percha remain in the site and induce the formation of foreign body granulomas. Although this does not preclude tooth movement, patients should be followed up every three months using periapical images to control the position of the material in relation to the tooth apex. "Pseudo" overfilling may be avoided if permanent filling is delayed until the time when orthodontic treatment is completed.


Assuntos
Endodontia , Ortodontia , Hidróxido de Cálcio , Tomada de Decisão Clínica , Guta-Percha , Humanos , Cimento de Óxido de Zinco e Eugenol
7.
Rev. cient. odontol ; 8(2): e015-e015, mayo-ago. 2020. ilus, tab
Artigo em Espanhol | LILACS, LIPECS | ID: biblio-1118804

RESUMO

Objetivo: Comparar la resistencia de unión a la dentina del cemento sellador tipo Grossman (Grossdent) y Apexit Plus (Ivoclar Vivadent) después de la medicación intraconducto de hidróxido de calcio Ca(OH)2 con vehículos de paramonoclorofenol alcanforado (PMCFA) y de clorhexidina al 2% (CHX). Metodología: Estudio experimental in vitro. Se seleccionó una muestra de 44 dientes humanos monorradiculares y fueron divididos en 4 grupos con medicación intraconducto (n = 9) y 2 grupos control. Los dientes fueron desinfectados y los conductos radiculares instrumentados usando una técnica híbrida. Se medicaron dos grupos con hidróxido de calcio más PMCFA y dos grupos con hidróxido de calcio más CHX 2% durante dos semanas. De cada grupo con medicación uno fue obturado con cemento sellador endodóntico Grossman y el otro con Apexit Plus, mediante la técnica de compactación lateral. Los grupos control fueron obturados solo con los dos cementos anteriormente mencionados. Se cortaron las muestras en discos de 2 mm de espesor y fueron sometidas a prueba de empuje con una máquina de ensayo universal. Resultados: El valor de la media más alta lo obtuvo el grupo medicado con Ca(OH)2 más PMCFA y obturado con Apexit Plus (m 3,742 y DE 0,808), mientras que el valor más bajo lo presentó el grupo de Ca(OH)2 más PMCFA obturado con cemento Grossman (m 1,371 y DE 0,699), presentaron diferencias significativas (p < 0,001). Conclusión: La resistencia de unión a la dentina radicular se ve influenciada por la medicación intraconducto previa a la obturación endodóntica. (AU)


Objective: Compare the dentin bond strength of Grossman ́s sealer (Grossdent) and Apexit Plus sealer (IvoclarVivadent) after intra-canal medication of calcium hydroxide Ca(OH)2 associated with vehicles of camphorated parachlorophenol (CMPC) and chlorhexidine 2% (CHX). Methodology: This was an in vitro experimental study. A sample of 44 monoradicular human teeth were disinfected and divided into 4 groups of intra-canal medication (N= 9) and 2 control groups. The teeth were disinfected and root canals were instrumented using a hybrid technique. Two groups were medicated with Ca(OH)2 and CMPC and two groups with Ca(OH)2 and CHX 2% for two weeks. One group of each medication was filled with Grossman ́s sealer and the others with Apexit Plus sealer using the lateral compaction technique. The control groups were filled only with the two sealers mentioned previously. Samples were cut into 2 mm thick discs and placed on a push test with a universal testing machine. Results: The highest value of the means was obtained by the group medicated with Ca(OH)2 in association with CMPC and filled with Apexit Plus (m 3.742; SD 0.808), while the lowest value was presented by the group of Ca(OH)2 associated with CMPC, filled with Grossman ́s sealer (m 1,371; SD 0.699). Statistical differences were considered with p<0.001. Conclusion: Root dentin bond strength is influenced by intra-canal medication prior to endodontic filling. (AU)


Assuntos
Humanos , Selantes de Fossas e Fissuras , Tratamento do Canal Radicular , Hidróxido de Cálcio/uso terapêutico , Endodontia , Epidemiologia Experimental
8.
Clin Oral Implants Res ; 31(10): 980-991, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32734630

RESUMO

OBJECTIVES: To present the characteristics and level of evidence (LOE) of clinical studies published in leading oral implantology journals during 2008-2018 and to explore whether the LOE of a study is associated with its scientific and social impact. MATERIALS AND METHODS: Clinical studies with direct relevance to the evaluation of healthcare interventions published in 2008, 2013, and 2018 in six oral implantology journals were identified via hand searches. A modified 4-level Oxford 2011 LOE tool was used to assess the LOE of all eligible studies. The citation count and Altmetric Attention Score (AAS) of each study were extracted from Web of Science and Altmetric Explorer, respectively. Thereafter, multivariable generalized estimation equation analyses were used to investigate the association between LOE, citation counts, and AAS, adjusting for potential confounding factors and clustering effects. RESULTS: A total of 763 clinical studies were included, among which the proportion of level-1, level-2, level-3, and level-4 studies was 2.4%, 30.4%, 40.2%, and 27.0%, respectively. During 2008-2018, the proportion of high LOE studies (level-1 and level-2) increased substantially from 24.6% to 43.1%, although the number of systematic reviews that only include randomized controlled trials has remained limited. According to multivariable analyses, the citation count (p = .002) and AAS (p = .005) of high LOE studies were both significantly greater than those of low LOE studies. CONCLUSIONS: During the past decade, the proportion of high LOE studies has increased substantially in the field of oral implantology. Clinical studies with higher LOE tend to have greater scientific and social impact.


Assuntos
Implantes Dentários , Endodontia , Fator de Impacto de Revistas , Publicações Periódicas como Assunto , Bibliometria
9.
Br Dent J ; 229(3): 169-175, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32811936

RESUMO

COVID-19 (also known as coronavirus) has had a profound impact on dentistry, with all elective treatment grinding to a halt initially and a slow phased return to normal services. The guidance available regarding treating dental emergencies is currently advice, analgesia and antimicrobials, where indicated in the first instance. Some patients cannot be managed successfully with this approach and require face-to-face consultation. Unless dental practices have the appropriate PPE and follow strict infection prevention and control guidance, face-to-face consultation may not be possible. If treatment is required, this is based on minimum intervention and avoidance of aerosol generating procedures (AGPs) on patients who are free of COVID-19. COVID-19-positive or suspected patients still require treatment at designated Urgent Dental Care centres.The aim of this article is to provide an insight into the COVID-19 pandemic and its implications on current emergency dental care. Commonly presenting dental conditions which require endodontic management will be discussed. Finally, an endodontic management protocol is suggested. The intention of the protocol is to describe practical techniques to minimise potential viral load and reduce risk of COVID-19 transmission when AGPs are instigated.


Assuntos
Betacoronavirus , Infecções por Coronavirus , Assistência Odontológica , Endodontia , Pandemias , Pneumonia Viral , Humanos , Traumatismos Dentários
10.
Swiss Dent J ; (7-8): 584-591, 2020 Jul 20.
Artigo em Inglês | MEDLINE | ID: mdl-32674530

RESUMO

Endodontic teaching follows common concepts in the four Swiss dental schools. The aim of this survey was to ask former Swiss dental students how they adopted these endodontic concepts in clinical practice. All the graduates of the years 2012 and 2013 (n = 196) were targeted in 2018 using an internet-based anonymous questionnaire, which was based on five initial questions. One hundred forty-one individuals (participants) filled in these questions on their work situation and referral concepts (72% response rate). Those 111 participants who performed root canal treatments themselves were the focus group. They answered an additional 11 questions. Their affinity towards performing endodontic treatments was investigated. The use of rubber dam isolation served as a surrogate to see if biological principles were respected. Furthermore, it was asked which instrumentation systems they used in daily practice, and how they perceived the impact of their superior/employer on these choices. Of the 141 survey participants 55 were men and 86 women. Thirty-eight of these (27%) reported to refer difficult endodontic cases. Individuals in the focus group had an overall positive attitude towards endodontics. There was very little variance in the responses between the four Swiss dental schools. The vast majority (86.5%) reported to use rubber dam routinely. More than half in the focus group used reciprocating systems, and only a few (22.5%) would still use the rotary system they were taught at university. There was a significantly (p < 0.05) higher perceived impact of the employer on choice of instrumenting system versus the use of rubber dam.


Assuntos
Endodontia , Padrões de Prática Odontológica , Feminino , Humanos , Masculino , Tratamento do Canal Radicular , Diques de Borracha , Estudantes , Inquéritos e Questionários
11.
Orv Hetil ; 161(30): 1260-1265, 2020 07.
Artigo em Húngaro | MEDLINE | ID: mdl-32653869

RESUMO

Surgical guides and three-dimensional (3D) planning softwares used in everyday dental implantology open new possibilities in other fields of dentistry. While using the operation microscope in endodontic microsurgery provides more precise apicectomy, there is still no consent on the exact localisation and size of the bony window to be prepared for this surgery. Our aim is to describe a new, guided endodontic microsurgery method when osteotomy and apicectomy are planned in a 3D software and performed with a trephine bur. Based on data from Cone Beam Computed Tomography, planning of the surgical guide was performed with a 3D planning software (Smart Guide, dicomLAB, Hungary) in order to define the size of the bony window, the angulation and the depth of the trephine bur during the apicectomy. After preparing a mucoperiosteal flap, with the help of the dentally supported surgical guide, the trephine bur removes the cortical bone and the apex of the root simultaniously. Following the modern microsurgical protocol, after performing the ultrasonic retrograde preparation, mineral trioxide aggregate (ProRoot MTA; Dentsply Maillefer, Ballaigues, Switzerland) is placed as a retrograde filling to close the resected area. After the uneventful healing period, a complete bony regeneration can be seen on the 1-year follow up X-ray. The patient is symptom-free. This technique is considered to be faster and more precise than the non-guided endodontic microsurgery carried out without the utilization of a trephine bur. Orv Hetil. 2020; 161(30): 1260-1265.


Assuntos
Apicectomia/métodos , Tomografia Computadorizada de Feixe Cônico/métodos , Cavidade Pulpar/cirurgia , Endodontia/métodos , Microcirurgia/métodos , Osteotomia/métodos , Impressão Tridimensional , Materiais Restauradores do Canal Radicular , Tratamento do Canal Radicular/métodos , Compostos de Alumínio , Compostos de Cálcio , Cavidade Pulpar/diagnóstico por imagem , Combinação de Medicamentos , Humanos , Hungria , Óxidos , Radiografia Dentária , Silicatos , Dente , Resultado do Tratamento , Procedimentos Cirúrgicos Ultrassônicos
12.
Stomatologija ; 21(1): 17-22, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32706342

RESUMO

The aim of this paper was to analyze the literature published in the research related to sodium hypochlorite induced injury. An internet search using search engines (Google, Researchgate and PubMed) was carried out. The keywords used for search were sodium hypochlorite, injury, cellulitis, apical extrusion, ulcer, endodontics. Full text articles of the articles were collected from the year 2007 to 2017. The data available from the clinical trials the journal articles were analyzed and presented in both tabular and descriptive patterns.


Assuntos
Endodontia , Hipoclorito de Sódio , Acidentes , Hipoclorito de Sódio/efeitos adversos
13.
J Endod ; 46(10): 1387-1402.e4, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32668310

RESUMO

INTRODUCTION: The purpose of this study was to evaluate the efficacy and safety of postoperative medications in decreasing pain after nonsurgical endodontic treatment using a network meta-analytic approach. METHODS: MEDLINE, Embase, CENTRAL, CINAHL, and Scopus were searched (until July 31, 2019). Two reviewers selected eligible randomized controlled trials and extracted and meta-analyzed data to estimate the treatment effects of pain assessed on a 0-100 scale (mean difference [MD]); 95% credible interval [CrI], and surface under the cumulative ranking curve [SUCRA]) at 6-8, 12, 24, and 48 hours postoperatively after the administration of various interventions. The Cochrane risk of bias tool was applied to eligible trials. The overall quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation approach obtained from the CINeMA Web application (University of Bern, Bern, Switzerland). RESULTS: Eight interventions among 11 studies were identified: nonsteroidal anti-inflammatory drugs (NSAIDs), NSAIDs + acetaminophen, NSAIDs + benzodiazepines, NSAIDs + opioids, corticosteroids, opioids, acetaminophen, and placebo. Compared with placebo, nonsurgical endodontic treatment pain 6-8 hours postoperatively improved with NSAIDs + acetaminophen (MD = -22; 95% CrI, -38 to -7.2; SUCRA = 73%; moderate confidence) and NSAIDs (MD = -21; 95% CrI, -34 to -7.6; SUCRA = 68%; very low confidence). At 12 and 24 hours, only NSAIDs were effective in decreasing postoperative pain. At 48 hours, no treatment resulted in significant pain reduction. Corticosteroids and opioids did not significantly decrease pain. No major safety concerns were reported. CONCLUSIONS: Very low- to moderate-quality evidence suggests that NSAIDs or NSAIDs + acetaminophen administered after nonsurgical endodontic treatment lead to a clinically relevant decrease in postoperative pain for patients with irreversible pulpitis or pulpal necrosis and are the most effective treatments available. Postoperative corticosteroids or opioids did not significantly decrease postoperative pain.


Assuntos
Acetaminofen/uso terapêutico , Anti-Inflamatórios não Esteroides/uso terapêutico , Analgésicos Opioides/uso terapêutico , Endodontia , Humanos , Metanálise em Rede , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/prevenção & controle
14.
J Endod ; 46(10): 1414-1419, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32628966

RESUMO

INTRODUCTION: The aim of the present study was to assess the number of cone-beam computed tomographic (CBCT) referral cases from a private endodontic practice during a 1-year observation period and to investigate if preoperative use of CBCT imaging has an impact on the final diagnosis and decision treatment planning. METHODS: The data of the patients who attended a private endodontic office in Athens, Greece, seeking endodontic treatment from January 2018 to December 2018 were scanned to retrieve all the cases that were further referred for CBCT evaluation. Two qualified (University of Athens) and experienced (more than 10 years of daily practicing) endodontists referred the cases for CBCT imaging. All CBCT cases were evaluated to collect information about the number of cases, the reason for referral, the diagnosis before and after CBCT interpretation, and the treatment planning decision and management of each case. Descriptive statistics were used to describe the clinical characteristics of the study sample. Logistic regression was used to estimate the odds ratios and their 95% confidence intervals. RESULTS: Of a total of 1029 patients (1269 teeth) referred for endodontic treatment, 86 patients were further referred for CBCT imaging (8.35% of the patients). A total of 104 teeth (8.2% of the teeth) were scanned. The most frequent reason for CBCT referral was surgical treatment planning. In 18 of 104 (17.3%) cases, there has been a change of the initial diagnosis after CBCT interpretation. Posterior and endodontically treated teeth without lesions presented 4.35 and 6.6 times times higher odds, respectively, of having a change in the initial diagnosis after CBCT evaluation. CONCLUSIONS: A small percentage of patients referred for endodontic treatment or retreatment are further referred by specialists for CBCT imaging. CBCT scanning was considered necessary both for all surgical treatment planning cases and the evaluation of inflammatory resorptive defects.


Assuntos
Endodontia , Endodontistas , Tomografia Computadorizada de Feixe Cônico , Grécia , Humanos , Encaminhamento e Consulta
15.
J Am Dent Assoc ; 151(8): 553, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32718476
17.
J Am Dent Assoc ; 151(8): 556-557, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32718481
19.
J Contemp Dent Pract ; 21(5): 473-474, 2020 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-32690825

RESUMO

Endodontic treatments tend to have very high successful rates in spite of the fact that they are quite an invasive, difficult procedure, especially in complex anatomies. Some complications can arise during or after a root canal procedure due to poor understanding of the anatomy and iatrogenic errors mainly during instrumentation. While some of these problems can be anticipated, many can never really be predicted.1-3 As a consequence, retreatment has become a well-defined field of knowledge and expertise in endodontics, since most complications can be solved with proper surgical or nonsurgical retreatments.4 Reinfection or persistent infections: Root canal treatment can fail due to a persistent bacterial infections or reinfections. These include inadequate shaping, cleaning, and obturation procedures, poor restorations, and exposure through a fracture. The remedies are dependent on the primary cause of the reinfection and the affected parts. Persistent infection is the major cause of short-term endodontic failures.5.


Assuntos
Endodontia , Tratamento do Canal Radicular , Retratamento
20.
J Endod ; 46(9): 1185-1194, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32590023

RESUMO

Odontogenic pain affects up to 54.9% of pregnant women1-3. This pain is often associated with pulpal and/or periapical infections that pose risks to women and their fetus. The American Dental Association in collaboration with the American College of Obstetricians and Gynecologists developed a consensus statement to affirm the importance of timely and appropriate oral health care as a critical component of a healthy pregnancy4. However, limited knowledge of endodontic procedure safety and related medication use often result in the avoidance of treatment during pregnancy. This article, a collaborative effort by specialists from endodontics, pediatric dentistry, and obstetrics, reviews the current evidence on the safety of medications commonly used in endodontics including local anesthetics, analgesics, anxiolytics, and antibiotics.


Assuntos
Endodontia , Analgésicos , Anestésicos Locais , Antibacterianos , Criança , Feminino , Humanos , Gravidez , Estados Unidos
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA