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1.
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem | ID: biblio-1047897

RESUMO

Objetivo: apreender experiências de pessoas idosas que participam de grupos de convivência. Método: estudo descritivo, exploratório de abordagem qualitativa realizado com doze pessoas idosas que frequentam grupos de convivência em um município no interior da Bahia. A coleta dos dados foi realizada por meio de entrevista semiestruturada, dezembro de 2017 a fevereiro de 2018. Os dados foram analisados e interpretados conforme a análise de conteúdo temática proposta por Laurence Bardin. Resultados: após a análise emergiram seis categorias: melhoria na condição de saúde; evitar a solidão, fonte de suporte social; apoio e incentivo familiar; atividades aquáticas e dança. Conclusão: O estudo mostrou que a participação de pessoas idosas em grupos de convivência se mostra necessária, devido melhorias na qualidade de vida, na autoestima, na construção de vínculos e apoio social, no qual auxilia-as em todo o processo de envelhecimento


Objective: to learn the experiences of elderly people who participate in social groups. Method: a descriptive, exploratory study with a qualitative approach carried out with twelve elderly people who attend social groups in a municipality in the interior of Bahia. The data were collected through a semi structured interview, from December 2017 to February 2018. Data were analyzed and interpreted according to the thematic content analysis proposed by Laurence Bardin. Results: seven categories emerged after the analysis: improvement in health status; avoid loneliness, source of social support; family support and encouragement; water activities and dancing. Conclusion: The study showed that the participation of elderly people in social groups is necessary due to improvements in the quality of life, self-esteem, the forging of bonds and social support that help them throughout the aging process


Objetivo: aprehender experiencias de personas mayores que participan en centros de convivencia. Método: estudio descriptivo, exploratorio de abordaje cualitativo realizado con doce personas mayores que frecuentan grupos de convivencia en un municipio en el interior de Bahía. La recolección de los datos fue realizada por medio de una entrevista semiestructurada, diciembre de 2017 a febrero de 2018. Los datos fueron analizados e interpretados según el análisis de contenido temático propuesto por Laurence Bardin. Resultados: después del análisis emergieron siete categorías: mejora en la condición de salud; evitar la soledad, fuente de soporte social; apoyo y fomento de la familia; actividades acuáticas y danza. Conclusión: el estudio mostró que la participación de personas mayores en grupos de convivencia se muestra necesaria, debido a mejoras en la calidad de vida, en la autoestima, en la construcción de vínculos y apoyo social, en el que las auxilia en todo el proceso de envejecimiento


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Qualidade de Vida , Centros Comunitários para Idosos/tendências , Envelhecimento Saudável , Pesquisa Qualitativa , Serviços de Saúde para Idosos
3.
Br J Nurs ; 28(21): 1414-1419, 2019 Nov 28.
Artigo em Inglês | MEDLINE | ID: mdl-31778329

RESUMO

Health promotion in later life can support healthy ageing and wellbeing. Nurses across the continuum of care have an important role in promoting positive health and wellbeing messages, but they must be cognisant of the need to engage in, modify and tailor health promotion for and with older adults. This article provides an overview of contemporary issues relevant to health promotion and older people, and the role and contribution of nurses.


Assuntos
Enfermagem Geriátrica , Promoção da Saúde , Papel do Profissional de Enfermagem , Idoso , Prioridades em Saúde , Envelhecimento Saudável , Humanos , Saúde Mental
4.
BMC Neurol ; 19(1): 233, 2019 Oct 14.
Artigo em Inglês | MEDLINE | ID: mdl-31607263

RESUMO

BACKGROUND: Neurodegeneration with brain iron accumulation (NBIA) is characterized by pathological iron accumulation in the subcortical nuclei and the cortex. As age-related iron accumulation studies in these structures are lacking in healthy aging, we aimed to characterize the dynamics of age-dependent iron accumulation in subcortical nuclei in healthy aging and selected NBIA cases. This is fundamental to understand the natural age-related iron deposition in the healthy brain prior to using this marker as a potential prognostic or diagnostic tool in neurodegenerative disorders. METHODS: Susceptibility-weighted imaging (SWI) scans from 81 healthy volunteers (0-79 years) and four genetically confirmed patients suffering from NBIA (2-14 years) were obtained. We scored the presence or absence of pencil lining of the motor cortex and putamen and analyzed the normalized SWI signal intensity ratio (NSIR) in five subcortical nuclei. RESULTS: In healthy subjects, an age-dependent increase of pencil lining occurred starting from the second decade of life and was present in all cases at the age of 50. In their first decade, NBIA patients showed no cortical pencil lining, but we did observe putaminal pencil lining at this stage. In healthy subjects, age and NSIR of all nuclei correlated positively and was particularly dynamic in early childhood until young adulthood in the globus pallidus, dentate nucleus and red nucleus, but not in the caudate nucleus and putamen. NBIA patients showed an increased NSIR in the globus pallidus only and not in the other subcortical nuclei compared to age-matched healthy subjects. CONCLUSIONS: Cortical pencil lining is part of healthy aging. This should be considered when assessing this as a potential marker in NBIA diagnosis and prognosis. Putaminal pencil lining has the potential to become a specific marker for some subtypes of NBIA in the first decade of life, as it was only observed in NBIA and not in age-matched healthy subjects. NSIR in the subcortical nuclei during healthy aging was shown to be dynamic, accentuating the importance of having an age-dependent baseline.


Assuntos
Encéfalo/patologia , Envelhecimento Saudável/patologia , Ferro/análise , Doenças Neurodegenerativas/patologia , Adulto , Idoso , Encéfalo/diagnóstico por imagem , Criança , Feminino , Humanos , Imagem por Ressonância Magnética/métodos , Masculino , Pessoa de Meia-Idade , Doenças Neurodegenerativas/diagnóstico por imagem , Adulto Jovem
5.
Maturitas ; 129: 6-11, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31547915

RESUMO

OBJECTIVE: To examine associations of parental ages at childbirth with healthy survival to age 90 years among older women. STUDY DESIGN: This study included a racially and ethnically diverse sub-cohort of 8,983 postmenopausal women from the larger Women's Health Initiative population, recruited during 1993-1998 and followed for up to 25 years through 2018. MAIN OUTCOME MEASURES: The outcome was categorized as: 1) healthy survival, defined as survival to age 90 without major morbidities (coronary heart disease, stroke, diabetes, cancer, or hip fracture) or mobility disability; 2) usual survival, defined as survival to age 90 without healthy aging (reference category); or 3) death before age 90. Women reported their own and their parents' birth years, and parental ages at childbirth were calculated and categorized as <25, 25-29, 30-34, or ≥35 years. RESULTS: Women were aged on average 71.3 (standard deviation 2.7; range 65-79) years at baseline. There was no significant association of maternal age at childbirth with healthy survival to age 90 or death before age 90. Women born to fathers aged ≥35 compared with 30-34 years at their births were more likely to achieve healthy than usual survival (OR, 1.15; 95% CI, 1.00-1.32). There was no association of paternal age at childbirth with death before age 90. CONCLUSIONS: Findings suggest that being born to older fathers was associated with healthy survival to age 90 among women who had survived to ages 65-79 years at study baseline. There was no association of maternal age at childbirth with healthy survival to age 90 among these older women.


Assuntos
Envelhecimento Saudável , Idade Materna , Idade Paterna , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Feminino , Nível de Saúde , Humanos , Masculino , Parto , Taxa de Sobrevida
6.
Artigo em Inglês | MEDLINE | ID: mdl-31510094

RESUMO

OBJECTIVE: This study examined the physical and social environment (facilities and activities) of Singapore's Recreational Centres (RCs) and female patrons' (>50 years) perception of the RC facilities and activities. MATERIALS AND METHODS: A total of 100 RCs were audited, and 22 face-to-face interviews were undertaken. RESULTS: Physical activity classes were the main activity offered (mean = eight classes per month), with walking (29.8%) and aerobics sessions (17.5%) being the most frequent. Nutrition classes and social activities were offered less often (mean = one class per month). The activities were well received by patrons, offering opportunities to interact while participating in physical activity and nutrition classes. However, the need for staff training, consideration of patron's abilities and the desire to engage in alternative activities were expressed. CONCLUSION: Overall, RCs' facilities and activities were well liked by the patrons but opportunities for improvements were identified. Regular reviews of facilities and activities through consultation with the RC patrons and managers are needed to ensure that the facilities and activities remain relevant and practical to the patrons. This will help to support active lifestyles and healthy eating practices among older adults residing within the community.


Assuntos
Envelhecimento Saudável , Instalações Esportivas e Recreacionais , Idoso , Exercício , Feminino , Humanos , Pessoa de Meia-Idade , Singapura
7.
Int J Equity Health ; 18(1): 140, 2019 09 05.
Artigo em Inglês | MEDLINE | ID: mdl-31488220

RESUMO

This article aims to clarify the moral underpinning of the policy framework of Healthy Ageing. It is a policy adopted by the World Health Organization designed to operate in alignment with the United Nations (UN) framework of the Sustainable Development Goals (SDGs) and the urgency given for the achievement of Universal Health Coverage (UHC). It particularly reflects on what, if anything, justifies protecting the most basic rights to health and well-being of older adults from possible policy trade-offs on the path to UHC.It argues that the dignity of older adults-under which are nested more specific ideas of self-respect, respect for autonomy, as well as the ethical priority for living well-underpins a categorical moral injunction against imposing the familiar utilitarian calculus as the default criterion for policy trade-offs across age groups. Respect for the dignity of older persons marks the moral threshold that every society ought to uphold even under conditions of relative resource scarcity.The moral constraint on permissible policy trade-offs relating to the health of older adults must reflect an understanding of older persons as active agents in the social structure of (their) well-being, not merely as passive vessels through which a good healthy life may or may not occur. We argue that there are three main domains where trade-offs are unacceptable from the moral point of view: it is impermissible (1) to prioritise key service(s) across different (vulnerable) age groups on the basis of actual or future contribution to society, (2) to prioritise across different age groups when co-prioritisation is warranted by the ethical theory, and (3), to always prioritise (by default) services that improve well-being over those that foster respect for dignity and autonomy.


Assuntos
Política de Saúde , Envelhecimento Saudável/ética , Idoso , Humanos , Pessoa de Meia-Idade , Princípios Morais , Cobertura Universal do Seguro de Saúde/organização & administração , Organização Mundial da Saúde
8.
Bull World Health Organ ; 97(8): 570-574, 2019 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-31384075

RESUMO

Problem: The measures for long-term care prevention that the Japanese government had introduced in 2006 were unsuccessful because of the failures to identify high-risk individuals and to enrol enough participants in the community prevention programme. Approach: The Japanese government shifted its primary strategy from a high-risk strategy to a community-based population strategy in 2015, by reforming the Long-term Care Insurance Act. This act is focusing on community-based care and social determinants of health. The Act and the government's plans for long-term care prevention are inspired by a social participation intervention called ikoino saron, that is gathering salons for people older than 65 years. These salons, managed by local volunteers, are held once or twice a month in communal spaces within walking distance of community members' homes and have a low participation fee. At the gatherings, older people can meet and interact with others through enjoyable, relaxing and sometimes educational programmes. Local setting: Japan has the world's largest ageing population, with 27.7% (35.2 million/126.7 million) of people older than 65 years. Relevant changes: Studies have shown that participation in the salons was associated with a halved incidence in long-term care needs and about one-third reduction in the risk of dementia onset. Evidence also suggests that financially vulnerable older adults were more likely to participate in such interventions. In 2017, 86.5% (1506/1741) of the Japanese municipalities had implemented the salons. Lessons learnt: Integrated care for long-term care prevention should consider interventions targeting the whole community in addition to high-risk individuals.


Assuntos
Serviços de Saúde Comunitária/organização & administração , Promoção da Saúde/organização & administração , Envelhecimento Saudável , Participação Social , Idoso , Idoso de 80 Anos ou mais , Demência/prevenção & controle , Feminino , Humanos , Japão/epidemiologia , Assistência de Longa Duração/organização & administração , Masculino , Determinantes Sociais da Saúde
9.
Artigo em Inglês | MEDLINE | ID: mdl-31398802

RESUMO

The context in which dependents, regardless of age, receive care affects their health. This study adapted the Home Observation for Measurement of the Environment (HOME) Inventory, originally designed for child development research, to assess the quality of stimulation and support available to elders in their habitual households in Sri Lanka. Whether the adapted domains correlated with indicators of health and well-being in ways consistent with the child development literature was then examined. Through mixed-methods research based on 248 household surveys, four focus groups, and 15 interviews, three domains emerged: Physical Environment, Variety of Stimulation, and Emotional and Verbal Responsiveness. Regression modeling revealed that a higher quality physical home environment correlated with two measures of cognitive function after adjusting for covariates, but no consistent association with two psychological well-being scales. In contrast, higher Variety of Stimulation scores correlated with better cognitive function and lower psychological distress. There was no consistent correlation between Responsiveness and selected health outcomes. Qualitative data indicate that elders are active household contributors who strive to achieve harmonious relations with coresident kin. These findings reveal notable synergies between early and late life efforts to improve cognitive and psychological health, and highlight household considerations for future healthy aging research.


Assuntos
Planejamento Ambiental/estatística & dados numéricos , Características da Família , Idoso Fragilizado/psicologia , Indicadores Básicos de Saúde , Envelhecimento Saudável , Qualidade de Vida/psicologia , Idoso , Idoso de 80 Anos ou mais , Família , Feminino , Grupos Focais , Humanos , Masculino , Sri Lanka
10.
Dement Geriatr Cogn Disord ; 47(4-6): 335-344, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31466060

RESUMO

BACKGROUND: The capacity to mitigate dementia symptomology despite the prevailing brain pathology has been attributed to cognitive reserve. OBJECTIVES: This study aimed to investigate how psychometric performance differs between individuals with a high school versus college education (surrogate measures for medium and high cognitive reserves) given the same level of brain pathology assessed using quantitative structural MRI. METHODS: We used data from the Aging Brain: Vasculature, Ischemia, and Behavior Study (ABVIB). Cognition was assessed using a neuropsychological battery that included those contained in the National Alzheimer's Coordinating Center (NACC) uniform data set. Participants with a medium and high cognitive reserve were matched by level of structural MRI changes, gender, and age. RESULTS: Matched-pair regression analyses indicated that individuals with a higher education had a significantly better performance in recognition and verbal fluency animals, working memory, and processing speed in complex tasks. Moreover, they had a better performance in interference trails compared to individuals with a high school education (medium cognitive reserve). CONCLUSIONS: Our findings suggest that, given the same level of brain pathology, individuals with a higher education (cognitive reserve) benefit from a superior performance in semantic memory and executive functioning. Differences in these cognitive domains may be key pathways explaining how individuals with a high cognitive reserve are able to diminish dementia symptomatology despite physical changes in the brain.


Assuntos
Envelhecimento/psicologia , Cognição/fisiologia , Reserva Cognitiva/fisiologia , Escolaridade , Psicometria , Idoso , Idoso de 80 Anos ou mais , Encéfalo/diagnóstico por imagem , Estudos de Coortes , Função Executiva , Feminino , Envelhecimento Saudável , Humanos , Estudos Longitudinais , Imagem por Ressonância Magnética , Masculino , Memória de Curto Prazo , Testes Neuropsicológicos , Estudos Prospectivos , Tempo de Reação
11.
Aging Clin Exp Res ; 31(10): 1351-1373, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31376119

RESUMO

Healthy aging is defined as the process of developing and maintaining the functional ability that enables wellbeing in older age. Healthy aging is dependent upon intrinsic capacity, a composite of physical and mental capacities, and the environment an individual inhabits and their interactions with it. Maintenance of musculoskeletal health during aging is a key determinant of functional ability. Sarcopenia, osteoporosis and osteoarthritis, are a triad of musculoskeletal diseases of aging that are major contributors to the global burden of disease and disability worldwide. The prevention and management of these disorders is of increasing importance with pressure mounting from the aging population. In a new initiative, the Chinese Medical Association, Chinese Society of Osteoporosis and Bone Mineral Research, and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases jointly organized a symposium to discuss current practices and policies in the management of musculoskeletal aging. The meeting allowed experts from Europe and China to share their experience and recommendations for the management of these three major diseases. Discussing and analyzing similarities and differences in their practice should lead, through a mutual enrichment of knowledge, to better management of these diseases, in order to preserve intrinsic capacity and retard the age-related degradation of physical ability. In future, it is hoped that sharing of knowledge and best practice will advance global strategies to reduce the burden of musculoskeletal disease and promote healthy aging tailored to meet the individual patient's needs.


Assuntos
Doenças Musculoesqueléticas , Idoso , Envelhecimento Saudável , Humanos , Doenças Musculoesqueléticas/epidemiologia , Osteoartrite/epidemiologia , Osteoporose/epidemiologia , Sarcopenia
12.
Medicine (Baltimore) ; 98(35): e16955, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31464936

RESUMO

BACKGROUND: Frailty has become one of the biggest challenges in facilitating healthy aging. Our study aims to investigate the association between physical activity and the risk of frailty, meanwhile, conduct a dose-response to observe the relationship between physical activity volume and frailty. METHOD: We will systematically search six databases to identify cohort studies assessing the association between physical activity and risk of frailty. Risk of bias of individual study will be assessed using the Newcastle-Ottawa Scale. Data will be analyzed by using STATA V.12.0. RESULTS: The results of this study will be published in a peer-reviewed journal. CONCLUSION: We will first investigate whether specific-physical activity reduce the risk to onset frailty in healthy older adults. However, predictable heterogeneity may exist in our study because of the inconsistent definitions of frailty.


Assuntos
Exercício/fisiologia , Idoso Fragilizado , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Envelhecimento Saudável , Humanos , Vida Independente , Projetos de Pesquisa , Fatores de Risco
13.
Aging Clin Exp Res ; 31(12): 1719-1725, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31463926

RESUMO

The positive gerontological approach to aging has resulted in successive terminologies to describe the process of aging, including successful aging, active aging, healthy aging, or healthy and active aging, amongst others. Each definition proposed by geriatricians, psychologists, sociologists or public health specialists has been based on specific aspects of aging that are most important to the authors' discipline, explaining the current difficulty in determining which is the best set of criteria to determine "good aging". Two successive analyses of the measurements used in longitudinal studies from 1989 to 2018 testify to this heterogeneity in the types of questions proposed to evaluate the quality of the individual aging process. To confront this complexity, new and integrated indices have successively been proposed to quantify and qualify the survival period of aging individuals. The present paper aims to describe and compare the value of the "healthy aging index", the "modified healthy aging index", the "healthy aging score" and the "selfie aging test". Attempts to date to identify the best individual measurement of "aging well" have been interesting, and certainly show promise, but their limitations to specific populations call for more concerted effort from the scientific community to obtain worldwide validation. Another option would be to identify the best self-assessment questionnaire and include it in a mobile device, enabling longer term personal follow-up of aging functions. There is a clear lack of data of this type at present, and an urgent need to obtain such information, to enable early and targeted interventions.


Assuntos
Avaliação Geriátrica/métodos , Nível de Saúde , Envelhecimento Saudável/fisiologia , Idoso , Humanos , Estudos Longitudinais
14.
Nutrients ; 11(8)2019 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-31374892

RESUMO

Barley intake reportedly reduces the risk of cardiovascular disease, but effects on the systemic phenotypes during healthy aging have not yet been examined. Therefore, we examined the effects of barley on the lifespan; behavioral phenotypes, such as locomotor activity, and cognitive functions, and intestinal microbiome in the senescence-accelerated mouse-prone 8 (SAMP8) mouse. We prepared two mild high-fat diets by adding lard, in which the starch components of AIN-93G were replaced by rice or barley "Motchiriboshi." SAMP8 (four weeks old, male) mice were fed AIN-93G until eight weeks old, and then rice (rice group) or barley diet (rice: barley = 1:4, barley group) until death. Changes in aging-related phenotypes, object and spatial recognition, locomotor and balancing activities, and the intestinal microbiome were recorded. Moreover, plasma cholesterol levels were analyzed at 16 weeks old. Barley intake prolonged the lifespan by approximately four weeks, delayed locomotor atrophy, and reduced balancing ability and spatial recognition. Barley intake significantly increased the medium and small particle sizes of high-density lipoprotein (HDL) cholesterol, which is associated with a reduced risk of total stroke. The Bacteroidetes to Firmicutes ratio in the barley group was significantly higher than that in the rice group during aging. Thus, lifelong barley intake may have positive effects on healthy aging.


Assuntos
Ração Animal , Fenômenos Fisiológicos da Nutrição Animal , Comportamento Animal , Cognição , Envelhecimento Cognitivo/psicologia , Grão Comestível , Microbioma Gastrointestinal , Envelhecimento Saudável/psicologia , Hordeum , Fatores Etários , Animais , Biomarcadores/sangue , Glicemia/metabolismo , HDL-Colesterol/sangue , Envelhecimento Saudável/sangue , Locomoção , Longevidade , Masculino , Camundongos , Estado Nutricional , Valor Nutritivo , Equilíbrio Postural , Comportamento Espacial
15.
Genome Biol ; 20(1): 152, 2019 08 02.
Artigo em Inglês | MEDLINE | ID: mdl-31375147

RESUMO

Jacob and Speed did not identify even a single example of a '150-gene-set' that was statistically significant at classifying Alzheimer's disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings, below.


Assuntos
Doença de Alzheimer , Envelhecimento Saudável , Cognição , Nível de Saúde , Humanos , RNA
16.
Obstet Gynecol Clin North Am ; 46(3): 501-514, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31378291

RESUMO

Although American women spend approximately 30% to 40% of their lives in menopause, a state defined by the cessation of estrogen production by the ovaries, obstetricians and gynecologists in North America receive little formal education about menopausal health. Hormonal therapy has been available for more than 75 years; however, controversies surrounding its use have impacted training of care providers in all specialties. This article offers updates on care for menopausal women, focusing on symptomatology and health issues that arise related to the decline in all reproductive hormones. Lifestyle adaptations and nonmedical approaches, and nonhormonal and hormonal medications are discussed.


Assuntos
Terapia de Reposição de Estrogênios , Envelhecimento Saudável , Estilo de Vida , Menopausa/fisiologia , Adulto , Doenças Cardiovasculares , Feminino , Fogachos , Humanos , Libido , Menopausa/psicologia , Saúde Mental , Pessoa de Meia-Idade , Osteoporose Pós-Menopausa , Saúde da Mulher
17.
Rev Esc Enferm USP ; 53: e03476, 2019 Jul 29.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-31365724

RESUMO

OBJECTIVE: To understand the life experiences that favor the plenitude and transcendence of the elderly being. METHOD: Qualitative study of hermeneutical phenomenological approach. It was conducted from January 2014 to March 2017 in two social groups for seniors. Selection of participants was by intentional sampling with information saturation. Characteristics of participants: men or women aged 60 years and over. Data collection through a phenomenological interview. Study in compliance with the General Law of Health, Subject of Health Research and the Declaration of Helsinki. Analysis through the Heidegger's hermeneutic circle: Pre-understanding, understanding and interpretation. RESULTS: Units of meaning arose. Ontologically, seniors are revealed in their historicity and temporality, emphasize fear and anguish in their daily life, and fall into a feeling of nothing with the need to be authentic that is achieved through care. This understanding of the being is transcendence, and its manifestation is enlightenment. CONCLUSION: Transcendence is favored by care in the life cycle. Nursing as a science of care can promote actions that facilitate the reach of the encounter of seniors at different stages of their lives.


Assuntos
Envelhecimento/psicologia , Envelhecimento Saudável/psicologia , Acontecimentos que Mudam a Vida , Idoso , Feminino , Hermenêutica , Humanos , Entrevistas como Assunto , Masculino , Pessoa de Meia-Idade , Enfermagem/organização & administração , Pesquisa Qualitativa
18.
Eur J Epidemiol ; 34(10): 979-982, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31342230

RESUMO

At the crossroads between sciences, epidemiology brings together the social and the biological to examine social inequalities in health. The concept of biological capital represents the accumulated history of biological experiences, alongside the other forms of accumulated capital, notably cultural, economic and social. The ability to access the three other forms of individual capital and therefore position in life depends on inherited biological health/skills, epigenetic imprinting and the accumulation of embodied biological changes that make an individual more or less successful in life. We present results from analyses carried out within the Lifepath consortium, showing that the socioeconomic environment, from early life and over the lifecourse, is an important risk factor for health and partly works through its effects on biological mechanisms. We show that socially stratified pre-disease states related to ageing may be examined using biomarkers, and help underline areas and mechanisms to promote healthy ageing.


Assuntos
Disparidades nos Níveis de Saúde , Classe Social , Determinantes Sociais da Saúde , Fatores Socioeconômicos , Alostase , Biomarcadores , Envelhecimento Saudável , Humanos , Masculino
19.
Aging Clin Exp Res ; 31(11): 1689-1693, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31317518

RESUMO

Information and communication technology (ICT) within healthcare covers a range of technologies that aim to improve disease management or help modify health behaviors. We discuss clinical practice and system-related ICT challenges in Europe in relation to healthy ageing in people with non-communicable diseases (NCD). Although ICT use within healthcare is increasing, several challenges remain, including: (i) variations in ICT use within Europe; (ii) under-use of electronic health records; (iii) frequent use of single domain outcomes; (iv) shortage of clinical trials on current technologies; (v) lack of involvement of patients in ICT development; (vii) need to develop and adapt ICTs for people with cognitive or sensory impairment; and (viii) need to use longitudinal big data better. Close collaboration between key stakeholders (academia, biopharmaceutical and technology industries, healthcare, policy makers, patients, and caregivers) should foster both technological innovation and innovative models to facilitate more cost-effective approaches, ultimately leading to increased healthy ageing.


Assuntos
Assistência à Saúde/normas , Envelhecimento Saudável , Tecnologia da Informação , Europa (Continente) , Humanos , Doenças não Transmissíveis/terapia
20.
Nature ; 571(7764): 183-192, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-31292558

RESUMO

For several decades, understanding ageing and the processes that limit lifespan have challenged biologists. Thirty years ago, the biology of ageing gained unprecedented scientific credibility through the identification of gene variants that extend the lifespan of multicellular model organisms. Here we summarize the milestones that mark this scientific triumph, discuss different ageing pathways and processes, and suggest that ageing research is entering a new era that has unique medical, commercial and societal implications. We argue that this era marks an inflection point, not only in ageing research but also for all biological research that affects the human healthspan.


Assuntos
Envelhecimento/fisiologia , Pesquisa Biomédica , Envelhecimento Saudável/fisiologia , Rejuvenescimento/fisiologia , Envelhecimento/efeitos dos fármacos , Envelhecimento/genética , Relógios Circadianos , Ensaios Clínicos como Assunto , Envelhecimento Saudável/efeitos dos fármacos , Envelhecimento Saudável/genética , Humanos , Inflamação , Longevidade/efeitos dos fármacos , Longevidade/genética , Longevidade/fisiologia , Mitocôndrias/metabolismo , Estado Nutricional , Estresse Oxidativo , Transdução de Sinais
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