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1.
J Infect Dev Ctries ; 15(1): 58-68, 2021 Jan 31.
Artigo em Inglês | MEDLINE | ID: mdl-33571146

RESUMO

INTRODUCTION: SARS-CoV2 pandemic marks the need to pay attention to bacterial pathogens that can complicate the hospital stay of patients in the intensive care unit (ICU). ESKAPE bacteria which includes Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter cloacae are considered the most important, because of their close relationship with the development of ventilator-associated pneumonia (VAP). The aim of this work was to identify and characterize ESKAPE bacteria and to detect their possible clonal spread in medical devices, patients, and medical personnel of the ICU for COVID-19 patients of the Hospital Juarez de Mexico. METHODOLOGY: Genetic identification of ESKAPE bacteria was performed by analyzing the 16S rRNA gene. Resistance assays were performed according to the CLSI guidelines. Assembly of AdeABCRS operon and inhibition assays of pumps efflux in Acinetobacter baumannii isolates were performed. Associated gene involved in biofilm formation (icaA) was performed in isolates belonging to the Staphylococcus genus. Finally, typing by ERIC-PCR and characterization of mobile genetic element SCCmec were done. RESULTS: Heterogeneous distribution of ESKAPE and non-ESKAPE bacteria was detected in various medical devices, patients, and medical personnel. Acinetobacter baumannii and Staphylococcus aureus were the predominant ESKAPE members. The analysis of intergenic regions revealed an important clonal distribution of A. baumannii (AdeABCRS+). Genotyping of SCCmec mobile genetic elements and the icaA gene showed that there is no clonal distribution of S. aureus. CONCLUSIONS: Clonal spread of A. baumannii (AdeABCRS+) highlights the importance of adopting good practices for equipment disinfection, surfaces and management of COVID-19 patients.


Assuntos
Infecções por Acinetobacter/transmissão , Acinetobacter baumannii/isolamento & purificação , Infecção Hospitalar/prevenção & controle , Unidades de Terapia Intensiva , Acinetobacter baumannii/patogenicidade , Antibacterianos/farmacologia , Biofilmes/crescimento & desenvolvimento , Infecção Hospitalar/microbiologia , Farmacorresistência Bacteriana/genética , Equipamentos e Provisões/microbiologia , Genótipo , Humanos , Sequências Repetitivas Dispersas , México , Pneumonia Associada à Ventilação Mecânica/microbiologia
2.
BMC Public Health ; 20(1): 1561, 2020 Oct 16.
Artigo em Inglês | MEDLINE | ID: mdl-33066745

RESUMO

BACKGROUND: With many medical equipment in hospitals coming in direct contact with healthcare workers, patients, technicians, cleaners and sometimes care givers, it is important to pay close attention to their capacity in harboring potentially harmful pathogens. The goal of this study was to assess the role that medical equipment may potentially play in hospital acquired infections in four public health facilities in Uganda. METHODS: A cross-sectional study was conducted from December 2017 to January 2018 in four public health facilities in Uganda. Each piece of equipment from the neonatal department, imaging department or operating theatre were swabbed at three distinct points: a location in contact with the patient, a location in contact with the user, and a remote location unlikely to be contacted by either the patient or the user. The swabs were analyzed for bacterial growth using standard microbiological methods. Seventeen bacterial isolates were randomly selected and tested for susceptibility/resistance to common antibiotics. The data collected analyzed in STATA version 14. RESULTS: A total of 192 locations on 65 equipment were swabbed, with 60.4% of these locations testing positive (116/192). Nearly nine of ten equipment (57/65) tested positive for contamination in at least one location, and two out of three equipment (67.7%) tested positive in two or more locations. Of the 116 contaminated locations 52.6% were positive for Bacillus Species, 14.7% were positive for coagulase negative staphylococcus, 12.9% (15/116) were positive for E. coli, while all other bacterial species had a pooled prevalence of 19.8%. Interestingly, 55% of the remote locations were contaminated compared to 66% of the user contacted locations and 60% of the patient contacted locations. Further, 5/17 samples were resistant to at least three of the classes of antibiotics tested including penicillin, glycylcycline, tetracycline, trimethoprim sulfamethoxazole and urinary anti-infectives. CONCLUSION: These results provides strong support for strengthening overall disinfection/sterilization practices around medical equipment use in public health facilities in Uganda. There's also need for further research to make a direct link to the bacterial isolates identified and cases of infections recorded among patients in similar settings.


Assuntos
Infecção Hospitalar/epidemiologia , Contaminação de Equipamentos/estatística & dados numéricos , Equipamentos e Provisões/microbiologia , Hospitais Públicos , Centros de Atenção Terciária , Estudos Transversais , Humanos , Uganda/epidemiologia
3.
PLoS Pathog ; 16(1): e1008153, 2020 01.
Artigo em Inglês | MEDLINE | ID: mdl-31999804

RESUMO

Human space travel is on the verge of visiting Mars and, in the future, even more distant places in the solar system. These journeys will be also made by terrestrial microorganisms (hitchhiking on the bodies of astronauts or on scientific instruments) that, upon arrival, will come into contact with new planetary environments, despite the best measures to prevent contamination. These microorganisms could potentially adapt and grow in the new environments and subsequently recolonize and infect astronauts. An even more challenging situation would be if truly alien microorganisms will be present on these solar system bodies: What will be their pathogenic potential, and how would our immune host defenses react? It will be crucial to anticipate these situations and investigate how the immune system of humans might cope with modified terrestrial or alien microbes. We propose several scenarios that may be encountered and how to respond to these challenges.


Assuntos
Equipamentos e Provisões/microbiologia , Interações Hospedeiro-Patógeno , Sistema Imunitário/imunologia , Astronautas , Exobiologia , Meio Ambiente Extraterreno , Humanos , Voo Espacial , Astronave
5.
Food Sci Technol Int ; 26(1): 11-20, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31370696

RESUMO

Human ingestion of antimicrobial residues in dairy products is a problem of public health. In this study we evaluated antibacterial effectiveness of aqueous and ethanolic leaf extracts of Mangifera indica L. as a natural alternative for reduction of Staphylococcus spp. biofilms. Eight Staphylococcus spp. strains from cows with mastitis and the Staphylococcus aureus strain (ATCC 25923) were evaluated. High performance liquid chromatography indicated the presence of phenolic compounds in the aqueous extract. Agilent Technologies gas chromatography revealed the presence of phenolic compounds, carbohydrates, and gallic acid in ethanolic extract. The tannin contents were 2.27 ± 0.01 and 2.67 ± 0.01% for ethanolic extract and aqueous extract, respectively. Extracts were evaluated in agar diffusion test and the size of inhibition zones were compared. The ethanolic extract was the most effective, showing minimum inhibitory concentrations and minimum bactericidal concentrations between 1.8-7.5 and 15.1-45.3 mg/ml, respectively. After tannin removal, the extracts were less effective, indicating these secondary metabolites as one of the main antibacterial compounds. The ethanolic extract at 45.3 mg/ml reduced mature biofilms in teat rubber (average: 3.91 log reduction) and stainless steel (average: 3.87 log reduction) after 5 min of contact. The extracts of M. indica leaves represent natural alternatives against Staphylococcus spp. strains and the ethanolic extract shows potential as a natural sanitizer.


Assuntos
Antibacterianos/farmacologia , Biofilmes/efeitos dos fármacos , Mangifera/química , Extratos Vegetais/farmacologia , Staphylococcus/efeitos dos fármacos , Animais , Bovinos , Equipamentos e Provisões/microbiologia , Feminino , Mastite Bovina/microbiologia , Testes de Sensibilidade Microbiana , Folhas de Planta/química , Borracha , Aço Inoxidável , Infecções Estafilocócicas/microbiologia , Taninos/análise
6.
Ann Ist Super Sanita ; 55(4): 380-385, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31850866

RESUMO

Probiotics, defined as "living microorganisms that, whether ingested in useful amount, may have beneficial effects on human body", are widely used in various products for human use, such as dietary supplements, medical devices and pharmaceutical products. The European Directive on medical devices (MDs) (DDM 93/42), also includes those MDs containing live microorganisms, particularly probiotics, that may have various destinations of use, including that of assisting the therapy of several human pathologies. In this brief note we analyzed the use of probiotics in MDs and how probiotics administration could represent one of the new frontiers of scientific research on the prevention and treatment of various diseases. We'll analyze the literature on probiotics based MDs, to review their major targets in the therapy of some of the most common human pathologies: bacterial vaginosis and vaginitis, atopic dermatitis, infantile colic, obesity, type 2 diabetes, and pharyngotonsillitis.


Assuntos
Probióticos/administração & dosagem , Vaginose Bacteriana/terapia , Administração Oral , Adolescente , Adulto , Criança , Pré-Escolar , Cólica/terapia , Dermatite Atópica , Diabetes Mellitus Tipo 2/terapia , Método Duplo-Cego , Equipamentos e Provisões/microbiologia , Feminino , Humanos , Lactente , Recém-Nascido , Lactobacillus , Masculino , Obesidade/prevenção & controle , Obesidade/terapia , Faringite/terapia , Prebióticos/administração & dosagem , Prebióticos/efeitos adversos , Probióticos/efeitos adversos , Ensaios Clínicos Controlados Aleatórios como Assunto , Supositórios , Simbióticos/administração & dosagem , Simbióticos/efeitos adversos , Tonsilite/terapia , Vaginite/microbiologia , Vaginite/terapia , Vaginose Bacteriana/microbiologia
7.
Int J Mol Sci ; 20(20)2019 Oct 21.
Artigo em Inglês | MEDLINE | ID: mdl-31640211

RESUMO

Recent studies have shown that plasma can efficiently inactivate microbial pathogens such as bacteria, fungi, and viruses in addition to degrading toxins. Moreover, this technology is effective at inactivating pathogens on the surface of medical and dental devices, as well as agricultural products. The current practical applications of plasma technology range from sterilizing therapeutic medical devices to improving crop yields, as well as the area of food preservation. This review introduces recent advances and future perspectives in plasma technology, especially in applications related to disinfection and sterilization. We also introduce the latest studies, mainly focusing on the potential applications of plasma technology for the inactivation of microorganisms and the degradation of toxins.


Assuntos
Desinfecção/métodos , Plasma/fisiologia , Esterilização/métodos , Agricultura , Equipamentos e Provisões/microbiologia , Conservação de Alimentos , Humanos
8.
Artigo em Inglês | MEDLINE | ID: mdl-31548884

RESUMO

Background: We report a recurrent outbreak of postoperative infections with extended-spectrum ß-lactamase (ESBL)-producing E. cloacae complex in cardiac surgery patients, describe the outbreak investigation and highlight the infection control measures. Methods: Cases were defined as cardiac surgery patients in Ghent University Hospital who were not known preoperatively to carry ESBL-producing E. cloacae complex and who postoperatively had a positive culture for this multiresistant organism between May 2017 and January 2018. An epidemiological investigation, including a case-control study, and environmental investigation were conducted to identify the source of the outbreak. Clonal relatedness of ESBL-producing E. cloacae complex isolates collected from case patients was assessed using whole-genome sequencing-based studies. Results: Three separate outbreak episodes occurred over the course of 9 months. A total of 8, 4 and 6 patients met the case definition, respectively. All but one patients developed a clinical infection with ESBL-producing E. cloacae complex, most typically postoperative pneumonia. Overall mortality was 22% (4/18). Environmental cultures were negative, but epidemiological investigation pointed to transesophageal echocardiography (TEE) as the outbreak source. Of note, four TEE probes showed a similar pattern of damage, which very likely impeded adequate disinfection. The first and second outbreak episode were caused by the same clone, whereas a different strain was responsible for the third episode. Conclusions: Health professionals caring for cardiac surgery patients and infection control specialists should be aware of TEE as possible infection source. Caution must be exercised to prevent and detect damage of TEE probes.


Assuntos
Surtos de Doenças , Ecocardiografia Transesofagiana/instrumentação , Enterobacter cloacae/isolamento & purificação , Infecções por Enterobacteriaceae/epidemiologia , Equipamentos e Provisões/microbiologia , Complicações Pós-Operatórias/microbiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Antibacterianos/farmacologia , Procedimentos Cirúrgicos Cardíacos/efeitos adversos , Serviço Hospitalar de Cardiologia , Estudos de Casos e Controles , Enterobacter cloacae/genética , Infecções por Enterobacteriaceae/mortalidade , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Mortalidade , Complicações Pós-Operatórias/mortalidade , Recidiva , Sequenciamento Completo do Genoma , beta-Lactamases/metabolismo
9.
Nat Commun ; 10(1): 3434, 2019 07 31.
Artigo em Inglês | MEDLINE | ID: mdl-31366920

RESUMO

Bacterial contamination of biological channels, catheters or water resources is a major threat to public health, which can be amplified by the ability of bacteria to swim upstream. The mechanisms of this 'rheotaxis', the reorientation with respect to flow gradients, are still poorly understood. Here, we follow individual E. coli bacteria swimming at surfaces under shear flow using 3D Lagrangian tracking and fluorescent flagellar labelling. Three transitions are identified with increasing shear rate: Above a first critical shear rate, bacteria shift to swimming upstream. After a second threshold, we report the discovery of an oscillatory rheotaxis. Beyond a third transition, we further observe coexistence of rheotaxis along the positive and negative vorticity directions. A theoretical analysis explains these rheotaxis regimes and predicts the corresponding critical shear rates. Our results shed light on bacterial transport and reveal strategies for contamination prevention, rheotactic cell sorting, and microswimmer navigation in complex flow environments.


Assuntos
Escherichia coli/fisiologia , Hidrodinâmica , Locomoção/fisiologia , Equipamentos e Provisões/microbiologia , Fluorescência , Modelos Biológicos , Propriedades de Superfície , Movimentos da Água
10.
Int J Mol Sci ; 20(15)2019 Aug 03.
Artigo em Inglês | MEDLINE | ID: mdl-31382580

RESUMO

Present day awareness of biofilm colonization on polymeric surfaces has prompted the scientific community to develop an ever-increasing number of new materials with anti-biofilm features. However, compared to the large amount of work put into discovering potent biofilm inhibitors, only a small number of papers deal with their validation, a critical step in the translation of research into practical applications. This is due to the lack of standardized testing methods and/or of well-controlled in vivo studies that show biofilm prevention on polymeric surfaces; furthermore, there has been little correlation with the reduced incidence of material deterioration. Here an overview of the most common methods for studying biofilms and for testing the anti-biofilm properties of new surfaces is provided.


Assuntos
Bactérias/efeitos dos fármacos , Biofilmes/efeitos dos fármacos , Equipamentos e Provisões/microbiologia , Polímeros/farmacologia , Bactérias/crescimento & desenvolvimento , Bactérias/patogenicidade , Biofilmes/crescimento & desenvolvimento , Humanos , Polímeros/química , Propriedades de Superfície
11.
FEMS Microbiol Rev ; 43(6): 622-641, 2019 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-31420962

RESUMO

Staphylococcus aureus (S. aureus) is considered by the World Health Organization as a high priority pathogen for which new therapies are needed. This is particularly important for biofilm implant-associated infections once the only available treatment option implies a surgical procedure combined with antibiotic therapy. Consequently, these infections represent an economic burden for Healthcare Systems. A new strategy has emerged to tackle this problem: for small bugs, small particles. Here, we describe how nanotechnology-based systems have been studied to treat S. aureus biofilms. Their features, drawbacks and potentialities to impact the treatment of these infections are highlighted. Furthermore, we also outline biofilm models and assays required for preclinical validation of those nanosystems to smooth the process of clinical translation.


Assuntos
Antibacterianos/farmacologia , Biofilmes/efeitos dos fármacos , Nanotecnologia/métodos , Staphylococcus aureus/efeitos dos fármacos , Animais , Equipamentos e Provisões/microbiologia , Humanos , Camundongos , Testes de Sensibilidade Microbiana , Nanoestruturas , Infecções Relacionadas à Prótese/tratamento farmacológico , Infecções Estafilocócicas/tratamento farmacológico
12.
Artigo em Inglês | MEDLINE | ID: mdl-31183077

RESUMO

Background: Tablet computers are increasingly being used in hospital patient care and are often colonized with important human pathogens, while the impact of disinfection interventions remains controversial. Method: In a prospective hygiene intervention study we consecutively sampled tablet computers exclusively used in a high-resource general internal medicine tertiary care setting with high routine hygiene measures. Our aim was to examine the change in colonizing bacteria on tablet computers before and after the introduction of a mandatory twice daily tablet disinfection intervention. Microbial identification was performed by conventional culture, and the association of bacterial colonization with the intervention was investigated using logistic regression. Results: In a total of 168 samples we identified colonizing bacteria in 149 (89%) of samples. While the most commonly identified species were normal skin bacteria, Staphylococcus aureus found in 18 (11%) of samples was the most frequent potential pathogen. We did not detect any Enterococci or Enterobacteriaceae. The disinfection intervention was associated with substantially less overall bacterial colonization (odds ratio 0.16; 95%-CI 0.04-0.56), while specific colonization with Staphylococcus aureus was only slightly decreased (odds ratio 0.46; 95%-CI 0.16-1.29). Conclusion: Our results indicate that a twice daily disinfection can still substantially reduce bacterial colonization of in-hospital tablet computers used in a high-resource and high hygiene setting.


Assuntos
Bactérias/classificação , Infecção Hospitalar/prevenção & controle , Desinfecção/métodos , Equipamentos e Provisões/microbiologia , Bactérias/efeitos dos fármacos , Bactérias/isolamento & purificação , Computadores de Mão , Higiene das Mãos , Humanos , Modelos Logísticos , Estudos Prospectivos , Atenção Terciária à Saúde
13.
Molecules ; 24(12)2019 Jun 19.
Artigo em Inglês | MEDLINE | ID: mdl-31248162

RESUMO

Surgical site infections (SSIs) represent the most common nosocomial infections, and surgical sutures are optimal surfaces for bacterial adhesion and biofilm formation. Staphylococcus spp., Enterococcus spp., and Escherichia coli are the most commonly isolated microorganisms. The aim of this research was to evaluate the antibiofilm activity of a medical device (MD) containing TIAB, which is a silver-nanotech patented product. The antibacterial effect was evaluated against Staphylococcus aureus ATCC 29213, Enterococcus faecalis ATCC 29212, and E. coli ATCC 25922 by assessing the minimum inhibitory concentration (MIC) by the Alamar Blue® (AB) assay. The antibiofilm effect was determined by evaluation of the minimum biofilm inhibitory concentration (MBIC) and colony-forming unit (CFU) count. Subsequently, the MD was applied on sutures exposed to the bacterial species. The antimicrobial and antibiofilm effects were evaluated by the agar diffusion test method, confocal laser scanning microscopy (CLSM), and scanning electron microscopy (SEM). The MIC was determined for S. aureus and E. faecalis at 2 mg/mL, while the MBIC was 1.5 mg/mL for S. aureus and 1 mg/mL for E. faecalis. The formation of an inhibition zone around three different treated sutures confirmed the antimicrobial activity, while the SEM and CLSM analysis performed on the MD-treated sutures underlined the presence of a few adhesive cells, which were for the most part dead. The MD showed antimicrobial and antibiofilm activities versus S. aureus and E. faecalis, but a lower efficacy against E. coli. Surgical sutures coated with the MD have the potential to reduce SSIs as well as the risk of biofilm formation post-surgery.


Assuntos
Antibacterianos/química , Antibacterianos/farmacologia , Biofilmes/efeitos dos fármacos , Materiais Revestidos Biocompatíveis , Equipamentos e Provisões/efeitos adversos , Equipamentos e Provisões/microbiologia , Compostos de Prata/química , Infecção da Ferida Cirúrgica/etiologia , Bactérias/efeitos dos fármacos , Bactérias/ultraestrutura , Humanos , Testes de Sensibilidade Microbiana
14.
Biocontrol Sci ; 24(2): 89-96, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31204360

RESUMO

In 2017, 2 household washing machines which were used at a house in Saitama prefecture were tested for fungal flora sampling. The fungi were identified in detail via genetic analysis of the ITS region. The number of fungi which were isolated were 8.7×106~6.1×107 cfu/100cm2 and dematiaceous fungi such as Ochroconis musae, Exophiala, Cyphellophora, Knufia epidermidis were dominant. As for Knufia epidermidis, this is the first report for identification from a Japanese household. The number of isolated Cladosporium, which is common in the environment, was fewer compared with the above 4 genera. The identified fungi were Cladosporium halatolerans, which is recently being recognized as the main species of Cladosporium. In our research, we have cleaned the 2 washing machines with different bleaches. Residual fungi was detected in washing machine A, which was cleaned with an oxygen bleach. On the other hand, no fungi was detected in washing machine B, which was cleaned with a chlorine bleach.


Assuntos
Desinfecção/métodos , Equipamentos e Provisões/microbiologia , Características da Família , Fungos/classificação , Fungos/isolamento & purificação , Contagem de Colônia Microbiana , DNA Fúngico/química , DNA Fúngico/genética , DNA Espaçador Ribossômico/química , DNA Espaçador Ribossômico/genética , Japão , Filogenia , Análise de Sequência de DNA
15.
J Mater Sci Mater Med ; 30(7): 77, 2019 Jun 19.
Artigo em Inglês | MEDLINE | ID: mdl-31218489

RESUMO

Most hospitalized patients are carriers of biomedical devices. Infections associated with these devices cause great morbidity and mortality, especially in patients in intensive care units. Numerous strategies have been designed to prevent biofilm development on biodevices. However, biofilm formation is a complex process not fully clarified. In the current study, roughness and hydrophobicity of different biomaterials was analyzed to assess their influences on the biofilm formation of four leading etiological causes of healthcare-associated infections, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis and Candida albicans, using a CDC biofilm reactor. Hydrophobic materials allowed the formation of more abundant and profuse biofilms. Roughness had effect on biofilm formation, but its influence was not significant when material hydrophobicity was considered.


Assuntos
Materiais Biocompatíveis/química , Biofilmes/efeitos dos fármacos , Equipamentos e Provisões/microbiologia , Propriedades de Superfície , Aderência Bacteriana , Reatores Biológicos , Candida albicans , Contaminação de Equipamentos/prevenção & controle , Escherichia coli , Interações Hidrofóbicas e Hidrofílicas , Poliuretanos , Pseudomonas aeruginosa , Staphylococcus epidermidis
17.
Am J Infect Control ; 47S: A10-A16, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31146843

RESUMO

The complexity of medical devices has increased over the past 10 years, and outbreaks of infections due to contaminated devices have focused attention on the need to adequately clean medical devices in order to ensure the adequacy of disinfection and sterilization. There has been a paradigm shift in reprocessing of medical devices, with increased emphasis on a quality management systems approach that requires validated cleaning instructions from manufacturers and ongoing monitoring by reprocessing personnel to ensure adequacy of cleaning. This article reviews the current issues related to medical device reprocessing and summarizes the approaches used for monitoring cleaning efficacy for surgical instruments and flexible endoscopes.


Assuntos
Descontaminação/métodos , Transmissão de Doença Infecciosa/prevenção & controle , Desinfecção/métodos , Equipamentos e Provisões/microbiologia , Fômites/microbiologia , Controle de Qualidade , Humanos
18.
Am J Infect Control ; 47S: A23-A28, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31146846

RESUMO

"No-touch" decontamination devices are increasingly used as an adjunct to standard cleaning and disinfection in health care facilities. Although there is evidence that these devices are effective in reducing contamination, there are several areas of controversy regarding their use. This review addresses some of the questions frequently posed by infection prevention and environmental services personnel about decontamination devices.


Assuntos
Descontaminação/métodos , Desinfecção/métodos , Contaminação de Equipamentos , Equipamentos e Provisões/microbiologia , Instalações de Saúde , Humanos
19.
Am J Infect Control ; 47S: A39-A45, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31146849

RESUMO

There is a growing appreciation for the role of biofilm-embedded microbes in many different aspects of infection transmission. The format of biofilm includes traditional hydrated biofilm, build-up biofilm, and dry surface biofilm. The objectives of this article are to discuss how traditional biofilm differs from build-up biofilm and dry surface biofilm, and to review the evidence supporting infection transmission from biofilm that accumulates in reprocessed instruments and from dry biofilm that forms environmental reservoirs.


Assuntos
Biofilmes/crescimento & desenvolvimento , Descontaminação/métodos , Desinfecção/métodos , Microbiologia Ambiental , Equipamentos e Provisões/microbiologia , Fômites/microbiologia , Transmissão de Doença Infecciosa/prevenção & controle , Humanos
20.
Am J Infect Control ; 47S: A67-A71, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31146854

RESUMO

Technological advancements in health care can potentially have substantial benefits on efforts to improve patient care. Organizations are often hesitant to consider new devices or technologies, particularly if the new technology is expensive, not addressed in current standards, or affects multiple departments, such as the sterile processing department, operating room, and infection prevention. Organizations considering new technology should create a multidisciplinary risk assessment committee tasked with using a systematic approach to evaluate and make recommendations on new products or technologies.


Assuntos
Infecção Hospitalar/prevenção & controle , Equipamentos e Provisões/microbiologia , Instalações de Saúde , Esterilização/métodos , Esterilização/organização & administração , Humanos
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