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1.
J Matern Fetal Neonatal Med ; 31(13): 1703-1708, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28521546

RESUMO

BACKGROUND AND OBJECTIVE: Striae are linear depressions of the skin and causes psychological and sexual problems in person. Different methods are used to prevent and treat them but there is no definitive method. We compared the effect of Aloe vera gel and sweet almond oil on striae gravidarum. MATERIALS AND METHODS: In this double-blind clinical trial, 160 nulliparous women were enrolled and randomly divided into three case groups and one control group. The four groups were given 700 g Aloe vera, sweet almond oil, and base cream to use topically on the abdominal skin and forth group don't receive any medication as control group in five steps, they were examined study's variables (itching, erythema, and spread of striae) using statistical tests in SPSS. RESULT: The findings showed that Aloe vera and sweet almond oil creams are more effective than the base cream and the control group to decrease itching and erythema and to prevent the spread of striae on the surface of abdomen (p < .05); however, all three creams had a similar effect on the diameter and the number of striae (p > .05). CONCLUSIONS: Aloe vera and sweet almond oil creams reduce the itching of striae and prevent their progression.


Assuntos
Óleos Vegetais/administração & dosagem , Preparações de Plantas/administração & dosagem , Complicações na Gravidez/tratamento farmacológico , Estrias de Distensão/tratamento farmacológico , Administração Tópica , Adulto , Método Duplo-Cego , Eritema/classificação , Eritema/tratamento farmacológico , Feminino , Géis , Humanos , Gravidez , Prurido/classificação , Prurido/tratamento farmacológico , Adulto Jovem
3.
J Cosmet Laser Ther ; 18(5): 296-300, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26980669

RESUMO

BACKGROUND: The VISIA Red images were developed to document and measure facial skin erythema, but diffuse erythema cannot be fully segmented by the VISIA system due to the automatic thresholding segmentation method. Moreover, topical area analysis is not available in the system. MATERIALS AND METHODS: Erythema severity degrees of 20 simulated Red images were designated 1-20 with 1-20 inflammatory lesions for each, respectively. The RGB channel mean values of each simulated image were acquired by ImageJ and relative intensity of red values calculated. RESULTS: The relative intensity of red values positively correlate to erythema severity with a coefficient of 0.999345 (p < 0.001). We also proposed a method for calibration when pustules were present in the erythema area. The method was proved by mathematical reasoning and verified by certified dermatologists. CONCLUSION: We demonstrated a simple and more precise method to quantify and compare facial skin erythema by analyzing the RGB channel values of the VISIA Red images. Our method brings convenience for erythema evaluation in dermatological studies.


Assuntos
Colorimetria/instrumentação , Eritema/classificação , Face , Aumento da Imagem/métodos , Humanos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Índice de Gravidade de Doença , Pigmentação da Pele
6.
Actas Dermosifiliogr ; 105(8): 780-8, 2014 Oct.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-24996228

RESUMO

BACKGROUND: Phototesting is a technique that assesses the skin's sensitivity to UV radiation by determining the smallest dose of radiation capable of inducing erythema (minimal erythema dose [MED]) and anomalous responses to UV-A radiation. No phototesting protocol guidelines have been published to date. METHODOLOGY: This was a multicenter prospective cohort study in which 232 healthy volunteers were recruited at 9 hospitals. Phototests were carried out with solar simulators or fluorescent broadband UV-B lamps. Each individual received a total of 5 or 6 incremental doses of erythemal radiation and 4 doses of UV-A radiation. The results were read at 24hours. RESULTS: At hospitals where solar simulators were used, the mean (SD) MED values were 23 (8), 28 (4), 35 (4), and 51 (6) mJ/cm(2) for skin phototypes i to iv, respectively. At hospitals where broadband UV-B lamps were used, these values were 28 (5), 32 (3), and 34 (5) mJ/cm(2) for phototypes ii to iv, respectively. MED values lower than 7, 19, 27, and 38 mJ/cm(2) obtained with solar simulators were considered to indicate a pathologic response for phototypes I to IV, respectively. MED values lower than 18, 24, and 24mJ/cm(2) obtained with broadband UV-B lamps were considered to indicate a pathologic response for phototypes ii to iv, respectively. No anomalous responses were observed at UV-A radiation doses of up to 20J/cm(2). CONCLUSIONS: Results were homogeneous across centers, making it possible to standardize diagnostic phototesting for the various skin phototypes and establish threshold doses that define anomalous responses to UV radiation.


Assuntos
Eritema/classificação , Eritema/etiologia , Pele/efeitos da radiação , Raios Ultravioleta , Adulto , Idoso , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Testes Cutâneos , Luz Solar , Adulto Jovem
7.
J Headache Pain ; 15: 18, 2014 Mar 26.
Artigo em Inglês | MEDLINE | ID: mdl-24670221

RESUMO

Erythermalgia is a rare cutaneous disorder characterized by attacking of erythema, pain and increased temperature, which primarily involves the extremities and may infrequently extend to the neck, face, ears and even the scrotum. We reported an 18-year-old woman who presented with 3 years history of sole involvement of attacking erythema, pain and warmth over her face and ears without any other associations. The frequency and severity of the flares progressed gradually during the course. Cutaneous examination revealed erythema, increased temperature and tenderness on the face and ears during the flare. The symptoms could be relieved rapidly by cooling. Dermatoscope showed that vessels inside the erythema were more dilated during the episode than after application of ice. The lesion is considered a rare variant of erythermalgia with sole involvement of face and ears. The symptoms had mild response to oral antihistamines, topical steroids and tacrolimus, but had excellent response to the combinative therapy of aspirin and paroxetins.


Assuntos
Orelha/patologia , Eritema/diagnóstico , Eritromelalgia/diagnóstico , Face/patologia , Dor/diagnóstico , Adolescente , Temperatura Corporal , Eritema/classificação , Eritema/complicações , Eritromelalgia/classificação , Eritromelalgia/complicações , Feminino , Humanos , Dor/classificação , Dor/complicações , Síndrome
8.
Eur J Pediatr ; 173(2): 181-6, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23955516

RESUMO

UNLABELLED: The objectives of this study were (1) to devise a nasal trauma score for preterm infants receiving non-invasive respiratory support, (2) to compare the incidence of nasal trauma in preterm infants <32 weeks gestation randomised to either nasal continuous positive airway pressure (NCPAP) or heated humidified high-Flow nasal cannulae (HHHFNC), in the first 7 days post-extubation and (3) to assess the effect of two different nasal dressings in those assigned to NCPAP. We randomly assigned preterm ventilated infants to receive Vapotherm® HHHFNC or NCPAP post-extubation. Infants receiving HHHFNC were treated with Sticky Whiskers® and infants receiving NCPAP received either Sticky Whiskers® or Cannualaide® nasal dressings. Bedside nursing staff scored six sites on each infant's nose for erythema, bleeding or ulceration. Scores were recorded three times daily for the first 7 days post-extubation. The sum of these 21 scores was used as the summary measure of nasal trauma. The mean nasal trauma score for infants assigned HHHFNC was 2.8 (SD 5.7) compared to 11.7 for NCPAP (SD 10.4), p < 0.001. There was no difference in mean trauma score between infants on NCPAP assigned Sticky Whiskers® 14.4 (SD 12.5) or Cannualaide® 9.5 (SD 7.3), p = 0.06. CONCLUSION: HHHFNC resulted in significantly less nasal trauma in the first 7 days post-extubation than NCPAP and was most significant in infants <28 weeks of gestation. The use of protective dressings was not associated with decreased nasal trauma for infants on NCPAP.


Assuntos
Extubação/efeitos adversos , Extubação/instrumentação , Cateteres/efeitos adversos , Pressão Positiva Contínua nas Vias Aéreas/efeitos adversos , Pressão Positiva Contínua nas Vias Aéreas/instrumentação , Doenças do Prematuro/terapia , Nariz/lesões , Insuficiência Respiratória/terapia , Bandagens , Epistaxe/classificação , Epistaxe/etiologia , Desenho de Equipamento , Eritema/classificação , Eritema/etiologia , Feminino , Humanos , Recém-Nascido , Masculino , Índices de Gravidade do Trauma , Úlcera/classificação , Úlcera/etiologia
9.
Skin Res Technol ; 20(1): 8-13, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23711094

RESUMO

BACKGROUND: Facial erythema is a common but morbid condition caused by several inflammatory disorders. Since most of the current severity indexes lack objectivity and global assessment, the computer-aided image analysis (CAIA) has been suggested. OBJECTIVE: The purpose of this study is to compare the validity and efficacy of novel CAIA erythema index - erythema dose (ED) with two other CAIA indexes. METHODS: For mild, moderated and severe erytherotelangiectatic rosacea patients, their photographs of right cheek were assessed with red-blue difference index in image (RBI), a*, and ED. For each index, the differences between severity groups were analyzed. The correlations between the three indexes were evaluated. To evaluate the capability of differentiating the pathologic erythema from the red component of the normal skin, each index was calculated at both the erythema and normal area. RESULTS: The a* and ED significantly changed according to the severity, while the RBI did not. The ED was different between both mild-moderate and moderate-severe, while the a* only between mild-moderate. There was a strong positive correlation between a* and ED. The difference between erythema and normal skin was more prominent in ED than in a*. CONCLUSION: We confirmed that the ED is well correlated with both subjective assessment, as well as the other CAIA index a*. The ED has the advantage of specifically visualizing and analyzing the pathologic erythema.


Assuntos
Eritema/classificação , Eritema/diagnóstico , Dermatoses Faciais/classificação , Dermatoses Faciais/diagnóstico , Interpretação de Imagem Assistida por Computador/métodos , Fotografação/métodos , Índice de Gravidade de Doença , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Reconhecimento Automatizado de Padrão/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
10.
J Forensic Leg Med ; 20(6): 724-31, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23910870

RESUMO

INTRODUCTION: Inconsistencies abound in the current forensic literature regarding the definition, and as a result, the significance of female genital injury after sexual intercourse. These definitions are based on variables related to the anatomic locations that are examined, the actual physical findings types, and the methods used to detect the findings. PURPOSE: To derive and perform initial clinimetric analyses on a simple instrument that defines, and based on severity, quantifies external genital injury after sexual intercourse. The scale utilizes standard injury definitions and a standardized examination method. METHODS: After empirical investigation, it was determined that the application of the tool would require the use of magnification and toluidine blue in order to have the sensitivity to detect the majority of injuries that occur after sexual intercourse. Separate matrices were constructed based on anatomic locations and injury types from data collected from sexual assault genital injury examination forms. Principal Components Analyses were applied. A clinical model was constructed from the resultant variables, utilizing operational definitions and forming a template for the instrument. RESULTS: A twelve-factor instrument measuring five variables along five "types" of severity and two "classes" of severity ensued. The resultant instrument was tested for internal consistency and differential validity. Very good internal consistency was attained (Cronbach's Coefficient α = 0.8). In a pilot study, the scale was able to distinguish a cohort of sexual assault patients from one of consensual intercourse subjects based on type and class of injury (p < 0.0001). CONCLUSION: The findings presented demonstrate that while employing a standardized examination method, the Genital Injury Severity Scale has utility in defining and measuring external genital injury after sexual intercourse.


Assuntos
Coito , Exame Ginecológico , Escala de Gravidade do Ferimento , Vagina/lesões , Vulva/lesões , Corantes , Colposcopia , Equimose/classificação , Edema/classificação , Eritema/classificação , Feminino , Medicina Legal , Humanos , Lacerações/classificação , Análise de Componente Principal , Estupro , Cloreto de Tolônio
11.
Skin Res Technol ; 19(1): e157-66, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22672837

RESUMO

BACKGROUND/PURPOSE: This study aimed to develop a method for the assessment of allergic dermatitis by using the long-wavelength near-infrared spectrum (more than 1000 nm) to detect intracutaneous allergic type-specific elements. Such a method was realized by establishing a spectral classifier for the spectra of type I and type IV allergic dermatitis reactions. METHODS: Near-infrared spectral images of histamine-induced cutaneous reaction (type I) and contact hypersensitivity erythema elicited by squaric acid dibutylester (SADBE; type IV) were obtained, and the absorption spectra of normal and inflamed skin were extracted from these spectral images. A spectral classifier was established from these training datasets, and it was then applied to two test cases, red flare by methyl nicotinate (normal) and metal allergy (type IV). RESULTS: The spectral classifier established by canonical discriminant analysis (CDA) achieved very accurate detection (normal: 87.67%, type I: 87.00%, type IV: 98.5%). Furthermore, the test cases were also correctly classified: the red flare induced by methyl nicotinate was categorized as normal skin and the metal allergy was categorized as a type IV allergic reaction. CONCLUSIONS: These results suggest a possible application of near-infrared spectral imaging to the assessment of allergic dermatitis.


Assuntos
Dermatite Alérgica de Contato/patologia , Eritema/patologia , Espectroscopia de Luz Próxima ao Infravermelho/métodos , Adulto , Bases de Dados Factuais , Dermatite Alérgica de Contato/classificação , Análise Discriminante , Eritema/induzido quimicamente , Eritema/classificação , Histamina/efeitos adversos , Agonistas dos Receptores Histamínicos/efeitos adversos , Humanos , Injeções Intradérmicas , Masculino , Metais/efeitos adversos , Ácidos Nicotínicos/efeitos adversos , Oxiemoglobinas/metabolismo , Testes do Emplastro , Espectroscopia de Luz Próxima ao Infravermelho/instrumentação , Urticária/classificação , Urticária/patologia , Água/metabolismo , Adulto Jovem
12.
J Burn Care Res ; 34(3): e187-94, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23237819

RESUMO

Color measurements are an essential part of scar evaluation. Thus, vascularization (erythema) and pigmentation (melanin) are common outcome parameters in scar research. The aim of this study was to investigate the clinimetric properties and clinical feasibility of the Mexameter, Colorimeter, and the DSM II ColorMeter for objective measurements on skin and scars. Fifty scars with a mean age of 6 years (2 months to 53 years) were included. Reliability was tested using the single-measure interobserver intraclass correlation coefficient. Validity was determined by measuring the Pearson correlation with the Fitzpatrick skin type classification (for skin) and the Patient and Observer Scar Assessment Scale (for scar tissue). All three instruments provided reliable readings (intraclass correlation coefficient ≥ 0.83; confidence interval: 0.71-0.90) on normal skin and scar tissue. Parameters with the highest correlations with the Fitzpatrick classification were melanin (Mexameter), 0.72; ITA (Colorimeter), -0.74; and melanin (DSM II), 0.70. On scars, the highest correlations with the Patient and Observer Scar Assessment Scale vascularization scores were the following: erythema (Mexameter), 0.59; LAB2 (Colorimeter), 0.69; and erythema (DSM II), 0.66. For hyperpigmentation, the highest correlations were melanin (Mexameter), 0.75; ITA (Colorimeter), -0.80; and melanin (DSM II), 0.83. This study shows that all three instruments can provide reliable color data on skin and scars with a single measurement. The authors also demonstrated that they can assist in objective skin type classification. For scar assessment, the most valid parameters in each instrument were identified.


Assuntos
Cicatriz/classificação , Cor , Pigmentação da Pele , Adolescente , Adulto , Criança , Colorimetria , Eritema/classificação , Estudos de Viabilidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes
13.
G Ital Dermatol Venereol ; 147(1): 123-6, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22370577

RESUMO

"Reactive erythemas" is an umbrella term grouping several different conditions, all of which have in common the fact of being stereotypical inflammatory clinical patterns of the skin in response to disparate infectious, immune, or toxic factors. Typically, such eruptions are symmetrical or disseminated. The here reported cases are different. An elderly man underwent recurrent infections of an epidermoid cyst, accompanied by a typical erythema annulare centrifugum near the infectious focus. His grandson, aged ten months, presented with an infectious conjunctivitis, during the resolution of which two small annular lesions, compatible with annular erythema of infancy, appeared on the face. A man aged 42, respectively son and father of the two former patients, presented with an erythema multiforme target lesion proximally to an infected wound. There were no detectable predisposing factors in all cases. Familial cases of reactive erythemas have been reported. However, such limited distributions have not yet been described.


Assuntos
Eritema/patologia , Adulto , Idoso , Eritema/classificação , Eritema/genética , Humanos , Lactente , Masculino
15.
Photochem Photobiol ; 87(2): 483-6, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21366601

RESUMO

The standard erythema action spectrum provides an internationally accepted representation of the erythema-inducing effectiveness of wavelengths in the UV part of the spectrum. The action spectrum forms the basis of the UV index used for public health information, defines the standard erythema dose unit and the minimum erythema dose and is the default response spectrum aspired to by a range of UV radiometer manufacturers. However, there are several versions of this erythema action spectrum in use, and only one of them has been endorsed as a standard. While the differences in erythemally weighted radiation incurred by choice of action spectrum will be no more than a few percent, this uncertainty is unnecessary. Here we detail the differences in the different versions of erythema action spectra, illustrate the resulting effects in quantifying UV doses and encourage readers to use only the standard version of the action spectrum in the future.


Assuntos
Eritema , Pele/patologia , Pele/efeitos da radiação , Raios Ultravioleta , Eritema/classificação , Humanos
16.
J Dtsch Dermatol Ges ; 9(1): 48-9, 2011 Jan.
Artigo em Inglês, Alemão | MEDLINE | ID: mdl-20408937

RESUMO

Blaschkitis is an acquired, rare dermatitis that follows the lines of Blaschko. Many consider blaschkitis as a variant of lichen striatus, although authors felt that it is a separate entity. A 2½-year-old girl presented with multiple grouped papules along the lines of Blaschko on her trunk. The main differences to lichen striatus are illustrated. Our case supports the hypothesis that blaschkitis is an entity of its own.


Assuntos
Eritema/diagnóstico , Eritema/tratamento farmacológico , Erupções Liquenoides/diagnóstico , Erupções Liquenoides/tratamento farmacológico , Óxido de Zinco/uso terapêutico , Pré-Escolar , Fármacos Dermatológicos/uso terapêutico , Diagnóstico Diferencial , Eritema/classificação , Feminino , Humanos , Erupções Liquenoides/classificação , Resultado do Tratamento
17.
Actas Dermosifiliogr ; 101(6): 473-84, 2010 Jul.
Artigo em Espanhol | MEDLINE | ID: mdl-20738966

RESUMO

Many skin diseases appear as annular lesions. Some are more typical of adults or older children, whereas others usually appear in young children. Annular or figurate erythema of infancy comprises a group of dermatoses in which the primary lesion adopts an annular, oval circinate, or polycyclic pattern. Similarities in clinical presentation, age at onset, and duration of lesions mean that these conditions are difficult to diagnose; sometimes, they can only be identified by subtle differences in their clinicopathologic features. Clinical pictures enable us to distinguish one member of this group of diseases from another and also to differentiate them from other annular eruptions. For ease of description, we classify annular erythema of infancy into 2 types: conditions with a known etiology and conditions with characteristic reaction patterns but uncertain etiology.


Assuntos
Eritema/patologia , Algoritmos , Criança , Eritema/classificação , Humanos
19.
Dermatol Surg ; 36(4): 475-82, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20236297

RESUMO

BACKGROUND: Patients with facial atopic dermatitis (AD) experience psychological and social distress. OBJECTIVE: To evaluate the safety and the efficacy of intense pulsed light (IPL) treatment in patients with facial AD. MATERIALS AND METHODS: Eleven patients (9 men, 2 women; aged 14-39) with mild to moderate refractory facial AD were included in this study. In three separate sessions at 2-week intervals, the whole face was exposed to an IPL device using a 590-nm cut-off filter. Objective clinical response was examined using the Eczema Severity Score (ESS), a polarization color imaging system, and two dermatologists' evaluations. Data on quality of life were evaluated using the Dermatology Life Quality Index (DLQI). RESULTS: The ESS in 11 patients with facial AD was significantly lower 4 weeks after the third treatment (p=.005). Scaling (p=.003); edema, induration, and papules (p=.011); erythema (p=.009), and lichenification (p=.008) improved significantly. The erythema scale, examined using the polarization color imaging system, also decreased significantly (p=.04). No patients showed any noticeable side effects. Mean DLQI score improved significantly after the completion of therapy (from baseline to 4 weeks after the last IPL treatment; p=.005). CONCLUSION: IPL treatment could be used as an adjunct modality for the treatment of refractory facial AD with minimal side effects.


Assuntos
Dermatite Atópica/complicações , Eczema/terapia , Eritema/terapia , Fototerapia , Adolescente , Adulto , Técnicas Cosméticas , Eczema/classificação , Eczema/etiologia , Eritema/classificação , Eritema/etiologia , Face , Feminino , Seguimentos , Humanos , Masculino , Medição da Dor , Satisfação do Paciente , Qualidade de Vida , Resultado do Tratamento , Adulto Jovem
20.
Actas dermo-sifiliogr. (Ed. impr.) ; 100(supl.2): 88-109, dic. 2009. lus
Artigo em Espanhol | IBECS | ID: ibc-78821

RESUMO

La denominación de eritemas figurados comprende una serie de afecciones que se caracterizan por eritema, con o sin descamación, que adoptan formas anulares, de arcos de círculo o policíclicas, y que se extienden de forma centrífuga. La mayoría de estos cuadros son reacciones a factores desconocidos–inmunitarios, infecciosos, tumorales u otros– tienen un curso crónico, evolucionan por brotes y son recidivantes. A veces desaparecen si se erradica la causa, pero en general no hay tratamientos específicos. Pueden aparecer en cualquier momento de la vida; algunos son más frecuentes en los adultos y otros sólo en la infancia (AU)


The term erythema figuratum is used to refer to erythematous lesions—with or without desquamation—that spread centrifugally in annular, arcuate, or polycyclic forms. Most of these conditions are reactions to unknown factors (immune, infectious, tumoral, and other processes), follow a chronic course with exacerbations and remissions, and are recurrent. They may disappear if the underlying cause is eradicated, but in general there are no specific treatments. They may appear at any time in life; some are more common in adults whereas others only present during childhood (AU)


Assuntos
Humanos , Eritema/classificação , Sinais e Sintomas , Eritema/diagnóstico , Eritema/terapia , Diagnóstico Diferencial
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