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1.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 55(5): 289-295, 2020 May 09.
Artigo em Chinês | MEDLINE | ID: mdl-32392969

RESUMO

Dental erosion is a progressive loss and damage of tooth hard tissues caused by contacting acidic substances. It is an occupational disease for workers who make acidic products such as acids, vinegar, etc. In the past decades, a rising of prevalence rate of dental erosion, especially in the youth groups, along with the change of dietary habits and the increased consumption of sweet and acidic diets, has attracted public's attention. This article reviews and analyzes the literature on the prevalence, etiology, prevention and treatment of dental erosion, so as to provide guidance for early diagnosis and treatment of dental erosion and support for making occupational disease prevention strategies.


Assuntos
Erosão Dentária/diagnóstico , Erosão Dentária/etiologia , Erosão Dentária/prevenção & controle , Ácidos/efeitos adversos , Dieta , Humanos
2.
Braz Oral Res ; 33: e114, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31800865

RESUMO

This in vitro study aimed to evaluate the effect of different toothpastes on dental enamel subjected to an erosive cycle with and without exposure to cigarette smoke. Bovine enamel specimens were randomly allocated into 12 groups (n = 12). For the in vitro simulation of smoking, half the groups underwent an exposure cycle of 20 cigarettes per day for 5 days. Subsequently, all groups were subjected to a 5-day erosion cycle intercalating demineralization (1 min; 1% citric acid; pH = 3.5) and treatment with toothpaste slurries (2 min) of NaF, SnF2, F/Sn/Chitosan, F/CaSiO3/Na3PO4, and F/bioactive glass. The control group was immersed in distilled water. Surface microhardness (SMH) was measured initially, after exposure to smoke, and after the erosive cycle, and %SMH was calculated. At the end of the experimental cycle, surface roughness, profilometry, and atomic force microscopy (AFM) were performed. SMH increased after exposure to cigarette smoke (p < 0.05). After the erosive cycle, there were no differences between the presence and absence of cigarette smoke exposure in SMH and roughness (p > 0.05). Besides increasing enamel SMH, cigarette smoke did not prevent enamel loss after the erosion cycle (p < 0.05). In profilometry, roughness and surface loss had the lowest values in the groups treated with SnF2 and F/Sn/Chitosan (p < 0.05). AFM showed lower mineral loss with F/CaSiO3/Na3PO4 and F/Sn/Chitosan. For all groups, except F/CaSiO3/Na3PO4, cigarette smoke resulted in higher enamel wear. F/Sn/Chitosan showed the best results against erosion.


Assuntos
Fumar Cigarros/efeitos adversos , Esmalte Dentário/efeitos dos fármacos , Erosão Dentária/etiologia , Erosão Dentária/prevenção & controle , Cremes Dentais/uso terapêutico , Animais , Compostos de Cálcio/uso terapêutico , Cariostáticos/uso terapêutico , Bovinos , Quitosana/uso terapêutico , Testes de Dureza , Humanos , Microscopia de Força Atômica , Valores de Referência , Reprodutibilidade dos Testes , Saliva/química , Silicatos/uso terapêutico , Propriedades de Superfície/efeitos dos fármacos , Fatores de Tempo , Fluoretos de Estanho/uso terapêutico , Desmineralização do Dente/induzido quimicamente , Desmineralização do Dente/prevenção & controle , Água/química
3.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 54(7): 450-455, 2019 Jul 09.
Artigo em Chinês | MEDLINE | ID: mdl-31288324

RESUMO

Objective: To investigate the preventive effect of resin infiltration and adhesive on early erosive enamel wear. Methods: Orthodontic reduction premolars collected from Central Laboratory of Nanjing Stomatological Hospital, Medical School of Nanjing University were used to prepare 70 specimens. Forty samples were divided into eight groups (n=5) and treated with different conditions (pH=1.6, 2.4, 3.2 or 4.0 hydrochloric acid solution, etching time was 30 or 60 s), and the conditions for obtaining early erosive enamel samples were selected. Based on this procedure, thirty early erosive enamel samples were made and divided into three groups: control group, resin infiltration group, and adhesive group. And the treatment of 30 days acid abrasion cycle was carried out. Confocal microscopy was used to measure the thickness changes of enamel or material before and after cycle. Results: Early erosive enamel samples was obtained when pH was 4.0 and etching time was 60 s. After 30 days cycle, the wear of enamel was (29.71±6.72) µm in control group, (5.60±2.24) µm in resin infiltration group and (2.89±1.03) µm in adhesive group. In infiltration group and adhesive group, lower enamel was not affected by the cycle, and the material loss ratios of the infiltration resin group and adhesive group were 0.41±0.14 and 0.29±0.13, respectively. The ratio of material loss was not significantly different (P>0.05). But infiltration group lost (12.95±2.22) µm of enamel during the application of the material. Conclusions: Resin infiltration and adhesive have the same short-term protective effect against early erosive enamel wear. Adhesive has less damage to enamel and better effect.


Assuntos
Adesivos , Resinas Compostas , Esmalte Dentário , Ácido Clorídrico , Erosão Dentária , Adesivos/farmacologia , Dente Pré-Molar , Resinas Compostas/farmacologia , Esmalte Dentário/efeitos dos fármacos , Humanos , Ácido Clorídrico/farmacologia , Erosão Dentária/induzido quimicamente , Erosão Dentária/prevenção & controle
4.
Clin Oral Investig ; 23(12): 4455-4463, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30997568

RESUMO

OBJECTIVES: This single-centre, randomised, crossover study used a short-term in situ dental erosion remineralisation model to explore the remineralisation of acid-softened enamel in the 4-h period immediately following brushing with an anti-erosion, dentin hypersensitivity test dentifrice containing 1150 ppm fluoride (as sodium fluoride [NaF]) or a placebo dentifrice with no fluoride. MATERIALS AND METHODS: Fifty participants wearing a palatal appliance holding surface-softened bovine enamel specimens brushed their natural teeth with their assigned dentifrice. Specimens were removed at 5-, 10-, 15-, 30-, 60-, 120- and 240-min post brushing. Enamel remineralisation effect was evaluated at each timepoint by percent surface microhardness recovery (%SMHR) and enamel fluoride uptake (EFU). After a second in vitro erosive challenge, the percent relative erosion resistance (%RER) was calculated. RESULTS: Statistically significant differences in %SMHR were observed for the test dentifrice compared with the placebo dentifrice from the 60-min timepoint onwards (all p < 0.02; mean difference of 8.66 [95% CI 3.46, 13.87] at 60 min). At each specimen removal time, %RER and EFU were statistically significantly higher for the test dentifrice compared with the placebo dentifrice (p < 0.0001 for all). No treatment-related or serious adverse events were reported. CONCLUSIONS: The NaF-containing anti-erosion, dentin hypersensitivity dentifrice improved remineralisation of acid-softened enamel starting at 60 min of intra-oral exposure. It also improved enamel erosion resistance and fluoride uptake as early as 5 min after exposure to fluoridated dentifrice slurry. CLINICAL RELEVANCE: Brushing with a NaF-containing dentifrice can rapidly improve remineralisation, enamel erosion resistance and fluoride uptake.


Assuntos
Dentifrícios/farmacologia , Fluoretos/farmacologia , Erosão Dentária/prevenção & controle , Remineralização Dentária/métodos , Adolescente , Adulto , Idoso , Animais , Cariostáticos , Bovinos , Estudos Cross-Over , Esmalte Dentário , Feminino , Dureza , Humanos , Masculino , Pessoa de Meia-Idade , Fluoreto de Sódio , Resultado do Tratamento
5.
Compend Contin Educ Dent ; 40(2): 80-86; quiz 87, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30767547

RESUMO

Dental erosion is a multifactorial condition associated with chemical, biological, and behavioral factors whereby a non-bacterial chemical process leads to an irreversible loss of dental structure. Consequences of this erosive process include painful sensitivity, susceptibility to further erosion, mechanical wear, changes in occlusion, exposure of dental pulp, and poor esthetics. Substantial evidence has revealed new insights to diagnosing early stages of dental erosion and enabling novel preventive approaches to control its progression. In the context of outpatient medical/dental practice, clinicians often encounter patients with progressive dental erosion. This article summarizes published research in this area of dentistry to suggest guidelines that are clinically oriented but scientifically fundamental. It is aimed at helping clinicians effectively integrate this information into their professional evaluations of dental erosion with regard to diagnosis, risk factors, clinical signs, assessment, and clinical preventive strategies and treatment. Clinicians should address patient diet habits, educate patients on prevalence data, and inform them regarding potential acidic interactions, such as medically induced acidic conditions, that may ultimately lead to tooth destruction. Prevention of dental erosion, including the recognition of initial erosive lesions and the implementation of the early intervention, involves the clinical expertise of both the dentist and physician.


Assuntos
Erosão Dentária/prevenção & controle , Dentifrícios , Dieta , Progressão da Doença , Estética Dentária , Fluoretos Tópicos/administração & dosagem , Estilo de Vida Saudável , Humanos , Educação de Pacientes como Assunto , Encaminhamento e Consulta , Fatores de Risco , Erosão Dentária/complicações , Erosão Dentária/diagnóstico , Erosão Dentária/terapia
6.
Pesqui. bras. odontopediatria clín. integr ; 19(1): 4785, 01 Fevereiro 2019. tab
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-998223

RESUMO

Objective: To evaluate in situ the effect of toothpastes containing casein phosphopeptide - amorphous calcium phosphate (CPP-ACP) and casein phosphopeptide-amorphous calcium phosphate associated to fluoride (CPP-ACPF) on initial erosion prevention. Material and Methods: Bovine enamel blocks (n = 192) were randomly assigned into 4 phases according to the baseline surface hardness: GI: CPP-ACP Paste (MI Paste™), GII: CPP-ACPF Paste (MI Paste Plus™), GIII: Fluoridated paste and GIV: Placebo Paste. In each of the 4 crossover phases, twelve volunteers wore intraoral palatal appliances containing 4 enamel blocks for 2 hours, then the tested treatments were applied intraorally (3 min) and the appliance was maintained in the mouth for another 3 hours. After, the appliances were removed and immersed in hydrochloric acid (0.01 M, pH 2.3) for 30 seconds to promote erosive demineralization. The final surface hardness was evaluated and percentage of surface hardness loss was calculated. The data were analyzed by ANOVA and Tukey's test (α = 5%). Results: The application of CPP-ACP paste, independent of fluoride content, resulted in significant lower enamel hardness loss (GI: 9.26% ±3.48 and GII: 9.14% ±1.73) compared to NaF (GIII: 15.5% ± 3.94) and placebo (GIV: 16.7% ± 4.07) pastes, which did not show difference between them. Conclusion: The CPP-ACP pastes were able to reduce initial erosive demineralization in relation to fluoride and placebo pastes. Nevertheless the formulation of CPP-ACP with fluoride did not provide an additional benefit.


Assuntos
Erosão Dentária/prevenção & controle , Cremes Dentais , Fluoreto de Cálcio/administração & dosagem , Desmineralização do Dente/diagnóstico , Brasil , Método Duplo-Cego , Análise de Variância , Estatísticas não Paramétricas
7.
Arch Oral Biol ; 99: 156-160, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30690411

RESUMO

OBJECTIVE: To evaluate the effect of Er,Cr:YSGG laser associated or not with acidulated phosphate fluoride (APF) on the control of enamel erosion progression. DESIGN: Enamel slabs (4 mm × 4 mm × 2 mm) from bovine incisors were flattened, polished, and received a tape on their test surfaces, leaving a 4 mm × 1 mm area exposed. Specimens were eroded (10 min in 1% citric acid solution) and randomly assigned into 8 experimental groups (n = 10): Control (no treatment); F (APF gel, 1.23% F, pH 3.6-3.9); Er,Cr:YSGG laser irradiation (P1: 0.25 W, 20 Hz, 2.8 J/cm2, 56 W/cm2); Er,Cr:YSGG laser irradiation (P2: 0.50 W, 20 Hz, 5.7 J/cm2, 1136 W/cm2); Er,Cr:YSGG laser irradiation (P3: 0.75 W, 20 Hz, 8.5 J/cm2, 1704 W/cm2); F + Laser P1; F + Laser P2; F + Laser P3. Specimens were then subjected to erosive cycling (5 min immersion in 0.3% citric acid solution, followed by immersion in artificial saliva for 60 min; 4×/day for 5 days). At the end of cycling, surface loss (SL, in µm) was determined with optical profilometry. Selected specimens were further evaluated by environmental scanning electron microscopy (n = 3). Data were analyzed using Kruskal-Wallis and Tukey tests (α = 0.05). RESULTS: Group F + Laser P2 had the lowest SL value, differing significantly from the control; however, with no significant difference from the other groups. All groups, except F + Laser P2, showed no significant difference in SL when compared with the control. An irregular and rough surface, suggestive of a melting action of laser, was observed on enamel in Laser P2 and F + Laser P2 groups. CONCLUSIONS: Association of the Er,Cr:YSGG laser in parameter 2 with fluoride was the only treatment capable of controlling the progression of enamel erosion.


Assuntos
Esmalte Dentário/efeitos dos fármacos , Esmalte Dentário/efeitos da radiação , Fluoretos/uso terapêutico , Lasers de Estado Sólido/uso terapêutico , Erosão Dentária/radioterapia , Erosão Dentária/terapia , Animais , Bovinos , Ácido Cítrico/efeitos adversos , Esmalte Dentário/patologia , Progressão da Doença , Incisivo , Microscopia Eletrônica de Varredura , Saliva Artificial , Propriedades de Superfície , Erosão Dentária/patologia , Erosão Dentária/prevenção & controle , Remineralização Dentária
8.
Clin Oral Investig ; 23(10): 3713-3720, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30623309

RESUMO

OBJECTIVES: The aim of this study was to investigate the effect of a dentifrice that contains calcium silicate, sodium phosphate, and fluoride on erosive-abrasive enamel wear. MATERIAL AND METHODS: This randomized, single-blind in situ/ex vivo study was conducted with four crossover phases of 5 days (one group tested per phase). Bovine enamel blocks (n = 256) were allocated to 16 volunteers and 8 groups. The groups under study were test dentifrice, with calcium silicate, sodium phosphate, and 1450 ppm sodium monofluorophosphate; tin dentifrice, with 3500 ppm stannous chloride, 700 ppm amine fluoride, and 700 ppm sodium fluoride; conventional dentifrice, with 1450 ppm sodium monofluorophosphate; and control (deionized water). Half of the enamel blocks were subjected to erosion and the other half to erosion plus abrasion. The daily extraoral protocol consisted in four citric acid exposures (2 min) and two applications of dentifrice slurry on all blocks for 30 s; after, half of the blocks were brushed for 15 s. The response variable was enamel loss. Data were analyzed by two-way ANOVA and Fisher's test (p < 0.05). RESULTS: For erosion, the test dentifrice promoted less enamel loss than water (4.7 ± 3.1 and 5.8 ± 2.5 µm, respectively, p < 0.05), and did not differ from tin (4.8 ± 2.5 µm) and conventional (4.8 ± 1.4 µm) dentifrices (p > 0.05). However, the test dentifrice (7.7 ± 3.8 µm) promoted higher wear after erosive plus abrasive procedures than tin (5.4 ± 1.5 µm) and conventional (6.2 ± 1.7 µm, p < 0.05) dentifrices, and did not differ from water (6.9 ± 2.0 µm). CONCLUSIONS: The investigated dentifrice reduced enamel loss against acid challenge but had no effect against acid and brushing challenge. CLINICAL RELEVANCE: Little is known regarding the preventive effect of dentifrices indicated for dental erosion. The tested anti-erosive dentifrice was unable to protect enamel when erosion was associated to toothbrushing abrasion.


Assuntos
Compostos de Cálcio/química , Dentifrícios/química , Fosfatos/química , Silicatos/química , Fluoreto de Sódio/química , Erosão Dentária/prevenção & controle , Animais , Bovinos , Estudos Cross-Over , Esmalte Dentário , Humanos , Método Simples-Cego , Escovação Dentária
9.
Lasers Med Sci ; 34(3): 449-455, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30215185

RESUMO

To evaluate the effect of Er,Cr:YSGG laser, associated with fluoride application, on the prevention/control of dentin erosion. Dentin slabs were embedded in acrylic resin, flattened, and polished. Half of the specimens were previously eroded (10 min immersion in 1% citric acid solution) and half were kept sound. The specimens (n = 10 each substrate) were randomly allocated into the experimental groups, according to the following treatments: control (no treatment); APF gel (1.23% F, 1 min); Er,Cr:YSGG laser irradiation (P1: 0.25 W, 20 Hz, 2.8 J/cm2, tip S75, beam diameter of 750 µm, 1 mm away from the surface); Er,Cr:YSGG laser irradiation (P2: 0.50 W, 20 Hz, 5.7 J/cm2, tip S75, beam diameter of 750 µm, 1 mm away from the surface); APF gel + Er,Cr:YSGG laser P1 and; APF gel + Er,Cr:YSGG laser P2. Afterwards, the specimens underwent an erosion-remineralization cycling, consisting of a 5-min immersion into 0.3% citric acid, followed by 60-min exposure to artificial saliva. This procedure was repeated 4×/day, for 5 days. Surface loss (SL, in µm) was determined by optical profilometry. Specimens from each group were analyzed by environmental scanning electron microscopy (n = 3). Data were statistically analyzed (α = 0.05). For the eroded specimens, APF gel presented the lowest SL, being different from the control. For the sound specimens, none of the groups differed from the control, except for Er,Cr:YSGG laser P2, which presented the highest SL. When substrates were compared, only the eroded specimens of the control and APF + Er,Cr:YSGG laser P1 Groups showed higher SL. Selective structure removal was observed for the laser-treated groups. None of the Er,Cr:YSGG laser parameters were effective in the prevention/control dentin erosion. The laser was also unable to enhance the protection of fluoride against dentin erosion.


Assuntos
Fluoreto de Fosfato Acidulado/uso terapêutico , Dentina/efeitos dos fármacos , Progressão da Doença , Lasers de Estado Sólido/uso terapêutico , Erosão Dentária/tratamento farmacológico , Erosão Dentária/prevenção & controle , Animais , Bovinos , Dentina/ultraestrutura , Microscopia Eletrônica de Varredura
10.
Int J Dent Hyg ; 17(1): 85-92, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30216663

RESUMO

OBJECTIVES: The aim of this study was to learn more about levels of knowledge relating to erosive tooth wear and about the most desirable way of disseminating dental information among young adults. METHODS: The research was a cross-sectional study of 331 young adults (20-25 years old) attending 25 dental care practices. Participants were asked to fill out a questionnaire with questions about their background, knowledge relating to erosive tooth wear and the preferred way of acquiring information about erosive tooth wear. RESULTS: The results showed that there are gaps in the knowledge of young adults about erosive tooth wear. The knowledge score depended on educational level and dental information received in the past. The preferred way of acquiring information was chairside information from an oral health care professional complemented by tailored information in writing. CONCLUSION: There is a lack of knowledge among young adults about erosive tooth wear. They prefer to receive information from the oral health care professionals accompanied by tailored information in writing. Further research should focus on developing this tailored information in line with the advice given by the oral health care professional.


Assuntos
Conhecimento , Erosão Dentária/etiologia , Erosão Dentária/psicologia , Desgaste dos Dentes/etiologia , Desgaste dos Dentes/psicologia , Adulto , Pessoal Técnico de Saúde , Informação de Saúde ao Consumidor , Estudos Transversais , Assistência Odontológica , Escolaridade , Feminino , Humanos , Masculino , Educação de Pacientes como Assunto/métodos , Inquéritos e Questionários , Erosão Dentária/prevenção & controle , Desgaste dos Dentes/prevenção & controle , Adulto Jovem
11.
Caries Res ; 53(1): 1-9, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-29874648

RESUMO

This study investigated the effect of surfactants associated with sodium fluoride (NaF) on enamel erosion prevention, using an erosion-remineralization in vitro model. Sodium lauryl sulfate (SLS), polysorbate 20 (P20), and cocoamidopropyl betaine (CAPB) were tested, at concentrations of 1.0 and 1.5%, and associated or not with NaF (275 ppm). The control groups were distilled water and the NaF solution. Bovine enamel samples (n = 12) were prepared and submitted to a 5-day cycling model: acid challenge (0.3% citric acid, pH 2.6, 4×/day), human saliva (2 h, 4×/day), and the treatment solutions (2 min, 2×/day). The protective potential of the agents against initial erosion was assessed by microhardness and the surface loss by profilometry. Enamel surface wettability was determined by goniometry, protein adsorption was measured by spectroscopy (FTIR), and the KOH-soluble fluoride was quantified. Goniometry showed that SLS and CAPB increased enamel wettability. No differences were found among the surfactants regarding protein adsorption. Microhardness showed that SLS reduced NaF protection. P20 (1 and 1.5%) and CAPB 1.5% presented a protective effect, but lower than the NaF solution. Profilometry showed that CAPB protected enamel, but no agent associated with NaF promoted a higher protection than the NaF solution alone. KOH-soluble fluoride analysis showed that all surfactants reduced the fluoride adsorption on the enamel surface. Therefore, the surfactants tested (except for P20) changed the enamel surface energy. The SLS decreased the protective potential of NaF on initial erosion, but no tested agent interfered with the protective effect of NaF on enamel erosive wear.


Assuntos
Betaína/análogos & derivados , Cariostáticos/farmacologia , Esmalte Dentário/patologia , Polissorbatos/farmacologia , Dodecilsulfato de Sódio/farmacologia , Fluoreto de Sódio/farmacologia , Tensoativos/farmacologia , Erosão Dentária/prevenção & controle , Adsorção/efeitos dos fármacos , Análise de Variância , Animais , Betaína/química , Betaína/farmacologia , Bovinos , Ácido Cítrico/efeitos adversos , Esmalte Dentário/efeitos dos fármacos , Dureza , Polissorbatos/química , Saliva/fisiologia , Dodecilsulfato de Sódio/química , Tensoativos/química , Erosão Dentária/induzido quimicamente , Molhabilidade/efeitos dos fármacos , Espectroscopia por Absorção de Raios X
12.
Lasers Med Sci ; 34(5): 893-900, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30374705

RESUMO

This in vitro study evaluated the influence of the Er,Cr:YSGG laser, associated or not to desensitizing agents, in the prevention of acid erosion in bovine root dentin. Eighty dentin specimens were selected and divided into eight groups (n = 10): G1: negative control; G2: positive control (5% fluoride varnish-FV); G3: Er,Cr:YSGG laser; G4: FV + laser; G5: 3% potassium oxalate; G6: 3% potassium oxalate + laser; G7: biphasic calcium silicate/phosphate gel (gel); G8: gel + laser. Laser parameters: 0.5 W, 6.25 J/cm2 at 1-mm distance. The erosive drink used was a cola soft-drink (pH = 2.42 at 4 °C), lasting 5 min, twice a day, with 6-h intervals between the challenges, during 14 days. Kolmogorov-Smirnov and Levene's tests were satisfied. The surface roughness data were submitted to ANOVA and Tukey post hoc tests. For the wear profile, Kruskal-Wallis and Dunn post hoc tests were used. Afterwards, the Spearman correlation test was performed. All statistical tests assumed a significance level of 5% (α = 0.05). G1 presented the highest surface roughness value after the erosive challenge (3.586 µm2 ± 0.205 µm2) and the G7 presented the lowest surface roughness value after the erosive challenge (1.071 µm2 ± 0.180 µm2). For the lost volume, G4 presented the lowest percentage (9.7% ± 0.9%), while G1 had the highest percentage (41.8% ± 2.5%), both with p < 0.05. There was a weak correlation between the response variables (ρ = 0.33). All groups presented lower values of surface roughness and loss of volume when compared to the negative control group. For the surface roughness, the biphasic calcium silicate/phosphate gel presented the best result. For volume loss, the 5% fluoride varnish + Er,Cr:YSGG laser showed the best results compared to the other groups.


Assuntos
Ácidos/efeitos adversos , Dessensibilizantes Dentinários/farmacologia , Dentina/efeitos da radiação , Lasers de Estado Sólido , Erosão Dentária/prevenção & controle , Raiz Dentária/efeitos da radiação , Animais , Bovinos , Dentina/efeitos dos fármacos , Estatísticas não Paramétricas , Propriedades de Superfície , Raiz Dentária/efeitos dos fármacos
13.
Clin Oral Investig ; 23(5): 2103-2112, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30267277

RESUMO

OBJECTIVES: The aim of this double-blind, randomized in situ study was to evaluate the erosion-preventive effect of a specific set of CO2 laser parameters, associated or not with fluoride. METHODS: Two hundred forty bovine enamel blocks were prepared for individual palatal appliances (n = 6 samples/appliance). The study had four phases of 5 days each, with ten volunteers and the following treatments: CO2 laser irradiation (L), fluoride treatment (F), combined fluoride and laser treatment (FL), and no treatment, control (C). Laser irradiation was performed at 0.3 J/cm2 (5 µs/226 Hz/10.6 µm) and the fluoride gel contained AmF/NaF (12'500 ppm F-/pH = 4.8-6). For erosive demineralization, the appliances were immersed extra-orally in citric acid (0.05 M/20 min/pH = 2.3) twice daily. Analysis of enamel surface loss was done using a 3D-laser profilometer on 3 days. Additionally, fluoride uptake was quantified and scanning electron microscopies were done. Data were analyzed with repeated measures ANOVA and post hoc pairwise comparisons (α = 0.05). RESULTS: At all analyzing days, both laser groups caused the lowest means of enamel loss, which were also statistically significant lower than C (p < 0.05). At day 5, FL means ± SD (33.6 ± 12.6 µm) were even significantly lower than all other groups (C 67.8 ± 15.4 µm; F 57.5 ± 20.3 µm; L 46.8 ± 14.5 µm). Significantly increased enamel fluoride uptake was observed for both fluoride-containing groups (p < 0.05) at day 1. CONCLUSION: Compared to the control, the CO2 laser irradiation with a specific set of laser parameters (0.3 J/cm2/5 µs/226 Hz) either alone or in combination with a fluoride gel (AmF/NaF) could significantly decrease enamel erosive loss up to 5 days in situ. CLINICAL RELEVANCE: Combined CO2 laser-fluoride treatment has a significant anti-erosive effect.


Assuntos
Dióxido de Carbono , Esmalte Dentário/efeitos da radiação , Erosão Dentária/prevenção & controle , Adulto , Animais , Bovinos , Método Duplo-Cego , Feminino , Humanos , Masculino , Fluoreto de Sódio/uso terapêutico
14.
Clin Oral Investig ; 23(5): 2365-2370, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30302612

RESUMO

OBJECTIVE: Devising effective measures for the prevention of hydrochloric acid (HCl)-induced erosion is of great significance. This is even more important in dentine, in which products have limited diffusion. Therefore, agents that can bind to proteins forming an acid-resistant gel-like coat, such as sucralfate, may stand out as a promising alternative. This study investigated the protective effect of sucralfate suspensions against HCl-induced dental erosion. MATERIALS AND METHODS: In the first experiment, hydroxyapatite (HAp) crystals were pre-treated with a commercial sucralfate suspension (CoSS, pH 5.9), a stannous-containing sodium fluoride solution (NaF/SnCl2 pH 4.5), two prepared sucralfate suspensions (PrSS, pH 5.9 and 4.5), or deionized water (DI, control). HAp dissolution was measured using a pH-stat system. In a subsequent experiment, embedded/polished enamel and root dentine slabs were allocated into five groups to be treated with one of the tested substances prior to and during erosion-remineralization cycles (HCl-2 min + artificial saliva 60 min, two times per day, 5 days). Surface loss was assessed profilometrically. Data were analyzed by ANOVA and Tukey's tests. RESULTS: HAp dissolution was as follows: NaF/SnCl2 < CoSS < PrSS/pH 4.5, while PrSS/pH 5.9 = DI and both did not differ from CoSS and PrSS/pH 4.5. In enamel, surface loss did not differ between CoSS and PrSS/pH 4.5, with both having lower surface loss than PrSS/pH 5.9 and DI and NaF/SnCl2 differing only from DI. In root dentine, surface loss was as follows: CoSS < PrSS/pH 5.9 < (NaF/SnCl2 = DI), while PrSS/pH 4.5 = CoSS = PrSS/pH 5.9. CONCLUSION: Sucralfate suspension provided anti-erosive protection to HCl-induced erosion. CLINICAL RELEVANCE: Sucralfate may protect teeth against erosion caused by gastric acid.


Assuntos
Ácido Clorídrico/efeitos adversos , Sucralfato/farmacologia , Erosão Dentária/prevenção & controle , Animais , Bovinos , Esmalte Dentário/efeitos dos fármacos , Dentina/efeitos dos fármacos , Durapatita , Fluoretos , Fluoreto de Sódio , Erosão Dentária/induzido quimicamente
15.
Clin Oral Investig ; 23(1): 273-284, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29721706

RESUMO

AIM: To evaluate the erosive preventive effect of toothpastes in permanent (PT) and deciduous teeth (dt). DESIGN: Enamel samples were divided into five groups (n = 20): G1: placebo toothpaste; G2: NaF toothpaste; G3: AmF-NaF-SnCl2 anti-erosion toothpaste; G4: SnF2-toothpaste; and G5: NaF anti-erosion toothpaste for children. The samples were exposed to five erosion-abrasion cycles (artificial saliva incubation; 3 min in 1% citric acid; 2 min in slurry, toothbrush abrasion, 50 strokes, 200 g). Surface microhardness (SMH), surface specular reflection intensity (SRI), and cumulative surface loss (CSL) were measured. Comparisons among toothpastes were evaluated using Kruskal-Wallis tests and comparisons between PT and dt were evaluated using Wilcoxon's rank sum test. RESULTS: G1 exhibited significantly lower SMH values in PT than the other toothpastes (p < 0.05), with no significant differences among the others groups. In dt, G1 and G4 exhibited significantly different values than the other groups (p < 0.05). G4 exhibited lower values of SRI in both types of teeth. Deciduous teeth presented significantly higher SRI than PT (p < 0.05), except for G3. Deciduous teeth generally presented higher CSL than PT, except for G3. CONCLUSIONS: Deciduous teeth were more prone to mineral loss than permanent teeth. G5 exhibited better efficacy for both teeth, while G3 exhibited a better preventive effect only for deciduous teeth. CLINICAL RELEVANCE: Erosive tooth wear prevalence in children is growing and deciduous teeth are more susceptible than permanent teeth. Considering this, it is important to know the preventive effect of different toothpastes in an initial erosion-abrasion model.


Assuntos
Erosão Dentária/prevenção & controle , Cremes Dentais/farmacologia , Dente Pré-Molar , Ácido Cítrico , Dentição Permanente , Dureza , Humanos , Técnicas In Vitro , Dente Molar , Saliva Artificial , Fluoreto de Sódio/farmacologia , Propriedades de Superfície , Compostos de Estanho/farmacologia , Dente Decíduo , Escovação Dentária
16.
Lasers Med Sci ; 34(6): 1089-1097, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30415288

RESUMO

The purpose of this in vitro study was to evaluate the effect of a clinical preventive treatment using Er,Cr:YSGG laser irradiation on bovine enamel susceptibility after erosive challenge. Twelve sound bovine incisors were used and twenty-four enamel specimens were prepared in total. Two experimental groups (n = 12) were assigned as follows: Group 1 was the control group and in Group 2, the enamel specimens were irradiated with an Er,Cr:YSGG (2780 nm) laser system for 20 s, with average output power of 0.25 W, pulse repetition rate at 20 Hz without water or air flow and the pulse duration was fixed at 140 µsec. The tip diameter was 600 µm, the tip to tissue distance was 1 mm, the speed of handpiece movement was 2 mm/s, the power density was 88.34 W/cm2, and the fluence was 31.25 J/cm2. The specimens were submitted to erosive challenge using a common soft drink. Surface microhardness changes, surface roughness changes, and surface loss were evaluated after erosive challenge. The data were statistically analyzed using one-way ANOVA and Tukey's post-hoc test at a level of significance a = 0.05. Er,Cr:YSGG laser-treated enamel exhibited significantly less decrease in surface microhardness and significant less surface loss compared to control enamel after the erosive challenge (p < 0.05). The experimental groups did not show significant differences in surface roughness increase after the erosive challenge (p > 0.05). Er,Cr:YSGG laser treatment may be promising for the limitation of enamel erosive tooth wear induced by excessive consumption of soft drinks. Clinical studies are needed to clarify whether this protective effect is clinically significant.


Assuntos
Esmalte Dentário/efeitos da radiação , Lasers de Estado Sólido/uso terapêutico , Erosão Dentária/prevenção & controle , Erosão Dentária/cirurgia , Animais , Bovinos , Esmalte Dentário/ultraestrutura , Dureza , Incisivo/efeitos da radiação , Espectrometria por Raios X
17.
J Dent Educ ; 82(12): 1296-1304, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30504467

RESUMO

Dental erosion (DE) is a well-accepted multifactorial form of tooth wear involving acids. Due to its irreversible nature, recognizing the early signs is important to develop appropriate preventive strategies. However, its place in dental curricula remains unclear. Consensus has not been established regarding the integration of erosive tooth wear into core cariology curricula in North America. The extent to which DE is taught is questionable since etiology, risk assessment, and management are not all the same as for dental caries. The aim of this study was to survey U.S. and Canadian dental schools regarding their teaching of DE. Email invitations were sent to deans, chairs, and selected faculty members at all 76 U.S. and Canadian dental schools in 2016, asking them to either respond or forward the survey-link provided to the appropriate person in their school. Responses from the same school were combined for analysis. Respondents from 59 schools (77.6% response rate) responded to the survey, and all of them confirmed the inclusion of DE in their curricula. However, only 15.3% of respondents identified correctly all the clinical signs of DE. Although management through behavioral intervention was prioritized, diet analysis was often not a clinical requirement, and 45.8% of respondents did not teach any type of tooth wear index for monitoring. This study concluded that DE has a place in dental curricula, but whether this topic is adequately covered is questionable. There is a need to establish clearer topics and requirements emphasizing the diagnosis and management of DE, potentially in cariology curricula.


Assuntos
Educação em Odontologia/estatística & dados numéricos , Faculdades de Odontologia/estatística & dados numéricos , Erosão Dentária , Canadá , Currículo , Humanos , Inquéritos e Questionários , Erosão Dentária/diagnóstico , Erosão Dentária/etiologia , Erosão Dentária/prevenção & controle , Estados Unidos
18.
Microsc Res Tech ; 81(12): 1456-1466, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30295365

RESUMO

This study evaluated the antierosive effect applying a modified acidulated phosphate fluoride (APF) gel containing nano-hydroxyapatite (nHAp) on the enamel surface before erosion. After polishing, the exposed flat enamel surfaces (n = 7/group) from bovine incisors were treated with artificial saliva (S - negative control), orange juice (ERO), APF gel (positive control) and APF_nHAp gel. All samples were subjected to six cycles of demineralization (orange juice, pH ~ 3.5, 10 min) followed by remineralization (saliva, 37°C, 1 hr). The enamel surface morphology, topography, and inorganic composition were analyzed using scanning electron microscopy, roughness testing, and micro energy-dispersive X-ray fluorescence spectrometry, respectively. The mean (standard deviation) roughness values (Ra, µm) were S, 0.13 (0.05); ERO, 0.25 (0.07); APF, 0.22 (0.08); and APF_nHAp, 0.17 (0.04). Ra values were significantly higher after ERO (p < .01) and APF (p < .05) treatments than after S. The enamel surface morphology was altered by the treatments, except for the S specimens. The mineral content of the enamel showed a clear trend with Ca and P reduction in the order of APF < S < APF_nHAp < ERO and APF < S < ERO < APF_nHAp, respectively. We can conclude that APF gel increased mineral concentration on the enamel. Moreover, the APF_nHAp material modified the composition and morphology of the enamel surface.


Assuntos
Fluoreto de Fosfato Acidulado/administração & dosagem , Esmalte Dentário/efeitos dos fármacos , Durapatita/administração & dosagem , Erosão Dentária/prevenção & controle , Fluoreto de Fosfato Acidulado/química , Animais , Bovinos , Esmalte Dentário/metabolismo , Esmalte Dentário/ultraestrutura , Durapatita/química , Géis/administração & dosagem , Géis/química , Humanos , Microscopia Eletrônica de Varredura , Minerais/metabolismo , Desmineralização do Dente/metabolismo , Desmineralização do Dente/prevenção & controle , Erosão Dentária/metabolismo
19.
Arch Oral Biol ; 95: 68-73, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30064032

RESUMO

OBJECTIVE: Palm oil has demonstrated preventive potential against initial erosive demineralization in vitro. This in situ study evaluated the effect of palm oil alone or associated with stannous-containing (Sn) solution on preventing enamel loss from an erosive/abrasive challenge. DESIGN: This single-blind, randomized, crossover in situ/ex vivo study was developed in four phases (one per group of five days) with sixteen volunteers. Enamel blocks (n = 256) were allocated to groups according to the treatment: Palm oil; Palm oil plus Sn solution; Sn solution - positive control; and Deionized water - negative control. Half of the enamel blocks of each group was subjected to erosion and the other half to erosion + abrasion. The daily ex vivo protocol consisted of four citric acid immersions (2 min). Before the first and third acid exposure, the blocks were treated with the test solutions (1 drop/block) for 1 min followed by acid immersion and abrasive challenge (toothpaste was applied on all blocks and half were brushed for 15 s/block). Enamel loss was quantified profilometrically and data were analyzed by two-way ANOVA and Tukey's test (p < 0.05). RESULTS: A significant difference was found for type of treatment (p < 0.001); wear condition (p = 0.38) and the treatment x condition interaction (p = 0.33) was non-significant. Palm oil associated or not to Sn solution significantly reduced enamel wear in comparison with the negative control but did not differ from the positive control (p > 0.05). CONCLUSIONS: Palm oil was able to prevent enamel loss under erosive and erosive + abrasive challenges in a similar extend to stannous-containing commercial solution.


Assuntos
Óleo de Palmeira/farmacologia , Fluoretos de Estanho/farmacologia , Abrasão Dentária/prevenção & controle , Erosão Dentária/prevenção & controle , Adolescente , Adulto , Animais , Bovinos , Estudos Cross-Over , Feminino , Humanos , Técnicas In Vitro , Masculino , Método Simples-Cego
20.
Sci Rep ; 8(1): 10936, 2018 Jul 19.
Artigo em Inglês | MEDLINE | ID: mdl-30026515

RESUMO

The aim was to investigate if honey causes erosion and if salivary pellicle modified with honey, or its components, or the by-product propolis has a protective effect against dental erosion and adhesion of early bacterial colonizers. The tested substances were: 3 types of honey, methylglyoxal (MGO), hydrogen peroxide, propolis. First in the erosion experiment, 120 human enamel specimens were covered with salivary pellicle and modified with the substances. Then they were eroded with 1% citric acid, pH 3.6 for 2 min, before surface hardness was measured. In the microbiological assay, the enamel specimens (n = 126) covered with modified salivary pellicle were contaminated with bacterial suspensions. The antimicrobial activity of each substance and their effect on early bacterial colonizer adhesion and biofilm formation were determined. Despite a low pH, honey did not cause erosion. On the other hand, pellicle modification with the tested solutions did not protect the enamel from erosion. Microbiologically, the 3 honeys inhibited species-specific growth of oral bacteria. Propolis decreased initial attachment of Streptococcus gordonii, while one honey inhibited demineralization of enamel by biofilm. In conclusion, pellicle modification with honey, or its components, or propolis did neither protect against erosion nor promote it. Propolis presented some bacterial adhesion inhibition.


Assuntos
Aderência Bacteriana/efeitos dos fármacos , Mel/análise , Própole/farmacologia , Erosão Dentária/induzido quimicamente , Bactérias/efeitos dos fármacos , Bactérias/crescimento & desenvolvimento , Ácido Cítrico/efeitos adversos , Esmalte Dentário/efeitos dos fármacos , Humanos , Concentração de Íons de Hidrogênio , Modelos Biológicos , Propriedades de Superfície , Erosão Dentária/microbiologia , Erosão Dentária/prevenção & controle
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