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1.
Cutis ; 105(3): 146-147;149, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-32352431

RESUMO

Beau lines, onychomadesis, and retronychia are nail conditions with their own characteristic clinical findings. It has been hypothesized that these 3 disorders may share a common pathophysiologic mechanism of slowing and/or halting nail plate production at the nail matrix. We report the case of a 41-year-old woman who presented with concurrent Beau lines, onychomadesis, and retronychia 6 months following a diagnosis of scurvy. Simultaneous presentation of these 3 nail conditions is not commonly reported, and our case supports a shared pathophysiologic basis.


Assuntos
Doenças da Unha/etiologia , Escorbuto/complicações , Adulto , Feminino , Humanos , Doenças da Unha/diagnóstico , Escorbuto/diagnóstico
11.
Pediatrics ; 142(1)2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29950397

RESUMO

A 19-month-old girl with a history of asthma and atopic dermatitis presented to her pediatrician because of parental concerns of pallor and fatigue. On dietary history, it was discovered that she was a picky eater and consumed 26 oz of homogenous milk daily. Her physical examination was unremarkable aside from pallor, and both her height and weight plotted between the 50th and 75th percentile for age. Therefore, she was investigated for iron deficiency anemia and indeed her blood work was consistent. Despite appropriate iron supplementation and dietary milk restriction, there was no improvement in her hemoglobin or iron studies. Our expert panel examines the case and offers a differential diagnosis for a child presenting with treatment-resistant iron deficiency anemia.


Assuntos
Anemia Ferropriva/etiologia , Doença Celíaca/diagnóstico , Ferro/uso terapêutico , Escorbuto/complicações , Anemia Ferropriva/terapia , Doença Celíaca/complicações , Diagnóstico Diferencial , Dieta Livre de Glúten/métodos , Suplementos Nutricionais , Feminino , Hemoglobinas/análise , Humanos , Lactente
12.
Clin Med (Lond) ; 18(2): 180-182, 2018 03.
Artigo em Inglês | MEDLINE | ID: mdl-29626027

RESUMO

A 73-year-old man presented with bilateral leg pain and swelling, and no history of trauma or bleeding disorders. Clinical examination, biochemistry and magnetic resonance imaging of the thighs were suggestive of muscle haematomas. These progressed significantly during the admission, requiring blood transfusion. Normal vascular anatomy on computed tomography, renal and liver function, and absence of infection made a bleeding diathesis more likely. This may be caused by coagulation defects, platelet disorders and vascular fragility. An undetectable serum ascorbic acid level confirmed the clinical suspicion of scurvy, and administration of vitamin C resulted in rapid improvement. Our case provides a structured approach to the diagnosis of bleeding disorders and scurvy, a treatable and potentially fatal disease which is often forgotten.


Assuntos
Hematoma , Escorbuto , Idoso , Ácido Ascórbico/sangue , Hematoma/etiologia , Hematoma/patologia , Hematoma/fisiopatologia , Humanos , Masculino , Escorbuto/complicações , Escorbuto/diagnóstico , Escorbuto/patologia , Escorbuto/fisiopatologia
13.
BMJ Case Rep ; 20182018 Mar 30.
Artigo em Inglês | MEDLINE | ID: mdl-29602889

RESUMO

Scurvy is a nutritional disease caused by ascorbic acid deficiency and is potentially fatal. It was originally described in the 18th century by James Lind and associated with long sea voyages and insufficient citrus consumption. Its prevalence has declined markedly over the years but has still been described sporadically in certain countries. A 22-year-old woman with an anxiety disorder and anorexia nervosa, recent pregnancy and ongoing breast feeding, presented with a 10-day history of spontaneous haematomas in the lower limbs, gingivorrhagia and fatigue. The examination was remarkable for signs of minor bleeding without haemodynamic compromise, gonalgia and pale skin. Work-up studies revealed the presence of anaemia. Direct anamnesis identified a diet based solely of tea and carbohydrates due to distorted body image. With the working diagnosis of scurvy, nutritional support and oral vitamin C supplementation was initiated. Her symptoms and anaemia resolved in 30 days and the diagnosis was confirmed biochemically.


Assuntos
Anorexia Nervosa/complicações , Transtornos de Ansiedade/complicações , Aleitamento Materno , Dieta/efeitos adversos , Escorbuto/complicações , Escorbuto/diagnóstico , Adulto , Anemia/etiologia , Ácido Ascórbico/uso terapêutico , Diagnóstico Diferencial , Carboidratos da Dieta , Suplementos Nutricionais , Fadiga/etiologia , Feminino , Hemorragia Gengival/etiologia , Hematoma/etiologia , Humanos , Escorbuto/tratamento farmacológico , Chá , Adulto Jovem
14.
J Dent Child (Chic) ; 85(1): 40-42, 2018 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-29663975

RESUMO

Localized gingival enlargement associated with vitamin C deficiency (scurvy) is rarely encountered in the modern era. The purpose of this paper is to report a case of extensive inflammatory gingival enlargement in the mandibular anterior region associated with vitamin C deficiency in a 10 year-old boy. There was a significant improvement of the gingival enlargement seven days after starting oral vitamin C supplementation. Vitamin C deficiency should be included in the differential diagnosis of any gingival enlargement, especially in children.


Assuntos
Deficiência de Ácido Ascórbico/complicações , Crescimento Excessivo da Gengiva/etiologia , Escorbuto/complicações , Criança , Humanos , Masculino
15.
Int J Infect Dis ; 69: 99-102, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29425711

RESUMO

A case of scurvy in a 10-year-old boy with autism spectrum disorder is described. His clinical presentation was initially thought to be due to osteomyelitis, for which empirical antimicrobial therapy was initiated. Further invasive and ultimately unnecessary investigations were avoided when scurvy was considered in the context of a restricted diet and classic signs of vitamin C deficiency. Infectious diseases specialists should be aware of scurvy as an important mimicker of osteoarticular infections when involved in the care of patients at risk of nutritional deficiencies.


Assuntos
Transtorno do Espectro Autista/complicações , Osteomielite/diagnóstico , Escorbuto/diagnóstico , Anti-Infecciosos/uso terapêutico , Criança , Pesquisa Empírica , Humanos , Masculino , Escorbuto/complicações , Escorbuto/tratamento farmacológico
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