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1.
Food Chem ; 336: 127706, 2021 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-32768907

RESUMO

This research was aimed to investigate the formation of protein-bound Nε-carboxymethyllysine (CML) and Nε-carboxyethyllysine (CEL) in ground pork at 121 °C (5-30 min) as affected by sugars (1-9% w/w, glucose, fructose, lactose, and sucrose).The addition of reducing sugar significantly (P < 0.05) increased the levels of CML and CEL in heat treated pork samples. Even adding 1% of glucose in pork could lead to 3.8 and 4.0 times increase in the formation rate constant (zero-order) of CML and CEL, respectively. In a typical commercial sterilization process (121 °C, 30 min), adding glucose, fructose or lactose in pork resulted in an average increase of 224-581%, 26-276%, and 8-189% CML, and 217-720%, 213%-15.8 times, and 20-150% CEL, respectively, depending on the sugar concentration. Sucrose did not promote the formation of CML and CEL in pork during heating.


Assuntos
Lisina/análogos & derivados , Carne de Porco , Esterilização/métodos , Açúcares/química , Animais , Indústria de Processamento de Alimentos/métodos , Produtos Finais de Glicação Avançada/química , Lisina/química , Carne de Porco/análise
2.
Texto & contexto enferm ; 29: e20190047, Jan.-Dec. 2020. graf
Artigo em Inglês | LILACS, BDENF - Enfermagem | ID: biblio-1101975

RESUMO

ABSTRACT Objective: to present the development of interactive media to compose an organizational platform addressing technical procedures performed in Material and Sterilization Centers. Method: lapplied research regarding technological production conducted in the Instituto Nacional de Referências em Atendimento Clínico-Cirúrgico a Crianças, Adolescentes e Mulheres, Rio de Janeiro, RJ, Brazil. Procedures were organized into five stages carried out between March and August 2017: bibliographical review; selection of technical procedures and routines; establishing outlets to produce media with resources for photography and filming production,including animation; MSC collaborators reviewed and assessed the material; and the support device by which media (audio and video) would be freely accessed by collaborators was selected. Results: 60 interactive videos were developed using the procedures adopted in routine practices, based on Collegiate and Normative Resolutions and the institution's quality parameters. Conclusion: establishing interactive outlets was an innovative solution to a lack of financial resources, optimizing resources used in training, procedures and routine activities linked to the context of Material and Sterilization Centers.


RESUMEN Objetivo: presentar el proceso de producción de medios de comunicación interactivos para componer una plataforma organizacional sobre procedimientos técnicos en un Centro de Material y Esterilización. Método: investigación aplicada de producción tecnológica realizada en el Instituto Nacional de Referências em Atendimento Clínico-Cirúrgico a Crianças, Adolescentes e Mulheres, en Rio de Janeiro (Brasil). Los procedimientos para alcanzar los objetivos fueron organizados en cinco etapas, desarrolladas en el período de marzo a agosto de 2017: levantamiento de material bibliográfico; selección de los procedimientos y rutinas técnicas; creación de las salidas para producción de los medios de comunicación con recursos para producción de fotografías y películas, considerando la creación de animaciones de las imágenes; revisión y evaluación de la producción por colaboradores de los equipos del Centro de Material y Esterilización; selección del dispositivo de soporte, en el cual los medios de comunicación (audio y vídeo) quedaron disponibles para consulta de los colaboradores, para libre acceso en el sector. Resultados: fueron creados 60 vídeos interactivos, a partir de procedimientos adoptados en rutinas prácticas, basadas en Resoluciones Colegiadas y normativas, vinculadas con la temática y con la calidad de la institución. Conclusión: la creación de las salidas interactivas solucionó, de forma innovadora, la falta y el gasto financiero, además de optimizar los recursos utilizados en entrenamientos, procedimientos y actividades de rutina vinculados con la realidad del Centro de Material y Esterilización.


RESUMO Objetivo: apresentar o processo de produção de mídias interativas para compor uma plataforma organizacional sobre procedimentos técnicos em Centro de Material e Esterilização. Método: pesquisa aplicada de produção tecnológica realizada no Instituto Nacional de Referências em Atendimento Clínico-Cirúrgico a Crianças, Adolescentes e Mulheres, Rio de Janeiro (Brasil). Procedimentos para alcance dos objetivos foram organizados em cinco etapas, desenvolvidas no período de março a agosto de 2017: levantamento de material bibliográfico; escolha dos procedimentos e rotinas técnicas; criação das saídas para produção das mídias com recursos para produção de fotografias e filmagens, tendo em vista criação de animações das imagens; revisão e avaliação da produção por colaboradores das equipes do Centro de Material e Esterilização; escolha do dispositivo de suporte no qual as mídias (em áudio e vídeo) foram disponibilizadas para consulta dos colaboradores para livre acesso no setor. Resultados: foram criados 60 vídeos interativos, a partir de procedimentos adotados em rotinas práticas, baseados em Resoluções Colegiadas e normativas ligadas à temática e à qualidade da instituição. Conclusão: a criação das saídas interativas solucionou, de forma inovadora, a carência e o dispêndio financeiro, além de otimizar os recursos utilizados em treinamentos, procedimentos e atividades de rotina ligadas à realidade do Centro de Material e Esterilização.


Assuntos
Organização e Administração , Enfermagem , Informática em Enfermagem , Tecnologia da Informação , Recursos Audiovisuais , Esterilização , Recursos Financeiros em Saúde
3.
Zhejiang Da Xue Xue Bao Yi Xue Ban ; 49(5): 603-608, 2020 Oct 25.
Artigo em Chinês | MEDLINE | ID: mdl-33210487

RESUMO

OBJECTIVE: To establish reuse process of positive pressure powered air-filter protective hoods during coronavirus disease 2019 (COVID-19) epidemic. METHODS: The procedure of pretreatment, storage, recovery, cleaning, disinfection and sterilization process of positive pressure powered air-filter protective hoods, which were used in the treatment of COVID-19 infection patients was established in Central Sterile Supply Department of the hospital. The cleaning and disinfection effects of the protective hoods after treatment were examined by magnifying glass method, residual protein detection method, real-time PCR, and agar pour plate method. RESULTS: Twenty five used protective hoods underwent totally 135 times of washing, disinfecting and sterilizing procedures. After washing, all the protein residue tests and COVID-19 nucleic acid tests showed negative results. After sterilizing, all the protective hoods met sterility requirement. All the tested protective hoods were undamaged after reprocessing. CONCLUSIONS: The established reuse procedures for used positive pressure powered air-filter protective hoods are safe.


Assuntos
Filtros de Ar , Infecções por Coronavirus , Desinfecção , Reutilização de Equipamento , Pandemias , Pneumonia Viral , Esterilização , Filtros de Ar/normas , Filtros de Ar/virologia , Betacoronavirus , Infecções por Coronavirus/prevenção & controle , Desinfecção/normas , Reutilização de Equipamento/normas , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Esterilização/normas
4.
Zhejiang Da Xue Xue Bao Yi Xue Ban ; 49(5): 609-613, 2020 Oct 25.
Artigo em Chinês | MEDLINE | ID: mdl-33210488

RESUMO

OBJECTIVE: To compare three sterilizing methods for reusable medical goggles. METHODS: A total of 180 medical goggles of the same brand and same model were randomly divided into three groups. In group A the goggles were first soaked with 2000 mg/L chlorine-containing disinfectant and then cleaned manually; goggles in other two groups were sterilized using pre-programmed automatic spray cleaning and disinfection machine, the disinfection program was set to 90 ℃ for 5 min in group B and 70 ℃ for 30 min in group C. The quality of the sterilization was monitored by visual inspection with luminous magnifying glass and residual protein detection assay. User satisfaction on cleanliness of medical goggles, clarity of mirror surface and suitability of elastic bands was investigated with questionnaire survey. RESULTS: The qualification rates verified by visual inspection were 82.4%, 84.6%and 98.3%in group A, B and C, respectively, the qualification rate in group C was significantly higher than those in group B and group C (all P<0.05). The qualification rates verified by residual protein detection assay were 96.7%, 100.0%and 100.0%in group A, B and C, respectively (P>0.05). A total of 54 questionnaires were submitted for the survey. The satisfaction rates were 100.0%, 90.7%and 94.4% for cleanliness of medical goggles, clarity of mirror surface and suitability of elastic bands, respectively. CONCLUSIONS: Machinery sterilization set 70 ℃ for 30 min has better cleaning and sterilizing effects for reusable medical goggles.


Assuntos
Dispositivos de Proteção dos Olhos , Esterilização , Dispositivos de Proteção dos Olhos/normas , Esterilização/métodos , Inquéritos e Questionários
7.
Artigo em Inglês | MEDLINE | ID: mdl-33050590

RESUMO

In addition to looking for effective drugs and a vaccine, which are necessary to save and protect human health, it is also important to limit, or at least to slow, the spread of coronavirus. One important element in this action is the use of individual protective devices such as filtering facepiece masks. Currently, masks that use a mechanical filter, such as a HEPA (High Efficiency Particulate Air) filter, are often used. In some countries that do not have a well-developed healthcare system or in exceptional situations, there is a real and pressing need to restore filters for reuse. This article presents technical details for a very simple device for sterilization, including of HEPA polymer filters. The results of biological and microscopic tests confirming the effectiveness of the sterilization performed in the device are presented. The compact and portable design of the device also allows its use to disinfect other small surfaces, for example a small fragment of a floor, table, or bed.


Assuntos
Microbiologia do Ar , Infecção Hospitalar/prevenção & controle , Filtração , Máscaras , Esterilização/métodos , Raios Ultravioleta , Humanos
8.
Rev. SOBECC ; 25(3): 171-178, 30-09-2020.
Artigo em Português | LILACS | ID: biblio-1122816

RESUMO

Objetivo: Identificar, na literatura científica, as atividades do enfermeiro que atua no centro de material e esterilização. Método: Trata-se de revisão integrativa da literatura, com busca nas bases de dados Scopus, Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs), Scientific Electronic Library Online (SciELO), PubMed e Biblioteca Virtual em Saúde (BVS). Os descritores utilizados foram esterilização/sterilization, competência profissional/professional competence e central supply hospital associados às palavras-chave enfermeiro/nurse e central sterile supply. Encontraram-se 1.330 artigos, dos quais 11 foram selecionados para compor a amostra. Resultados: Evidenciaram-se pontos centrais referentes ao trabalho do enfermeiro, como gerenciamento do setor e desenvolvimento de atividades educativas, além dos desafios enfrentados, como não reconhecimento e desvalorização, falta de preparo e de educação permanente, riscos ocupacionais, carga horária de trabalho excessiva, má remuneração e desgastes físico e mental. Conclusão: Foi possível contextualizar e compreender as atividades e os principais desafios delas decorrentes no desenvolvimento do trabalho do enfermeiro no centro de material e esterilização, contribuindo, dessa forma, para a divulgação, o reconhecimento e a reflexão a respeito da referida temática.


Objective: To identify in the scientific literature the activities of nurses who work in the sterile processing department. Method: This is an integrative literature review performed by searching the databases Scopus, Latin American and Caribbean Health Sciences Literature (LILACS), Scientific Electronic Library Online (SciELO), PubMed, and Virtual Health Library (VHL). The descriptors used were esterilização/sterilization, competência profissional/professional competence, and central supply hospital associated with the keywords enfermeiro/nurse and central sterile supply. We found 1,330 articles and selected 11 of them to compose the sample. Results: Key aspects related to nurses' work stood out, such as sector management and development of educational activities, as well as the challenges faced by these professionals, including nonrecognition and underappreciation, lack of preparation and continuing education, occupational risks, excessive workload, low wages, and physical and mental exhaustion. Conclusion: We could contextualize and understand the activities and their main resulting challenges related to the development of nurses' work in the sterile processing department, thus contributing to the dissemination, recognition, and reflection on this theme.


Objetivo: Identificar, en la literatura científica, las actividades de enfermeros que trabajan en el Centro de Material y Esterilización. Método: Esta es una revisión de literatura integradora, que busca en las bases de datos SCOPUS, Literatura Latinoamericana y del Caribe en Ciencias de la Salud (LILACS); Biblioteca científica en línea electrónica (SCIELO), PubMed y biblioteca virtual de la salud (BVS). Los descriptores utilizados fueron esterilización/sterilization, competencia profesional/professional competence, asociados a las palabras clave enfermeiro/nurse y centro de suministros estériles/central sterile supply. Se encontraron 1.330 artículos, de los cuales 11 fueron seleccionados para componer la muestra. Resultados: se evidenciaron puntos centrales relacionados con el trabajo de la enfermera, como la gestión del sector y el desarrollo de actividades educativas, además de los desafíos enfrentados, como la falta de reconocimiento y apreciación, la falta de preparación y educación permanente, los riesgos laborales, la carga de trabajo excesiva, mal pago y agotamiento físico y mental. Conclusión: fue posible contextualizar y comprender las actividades y los principales desafíos derivados de ellas en el desarrollo del trabajo de la enfermera en el centro de materiales, contribuyendo así a la difusión, reconocimiento y reflexión sobre este tema.


Assuntos
Humanos , Esterilização , Enfermagem , Enfermeiras e Enfermeiros , Competência Profissional , Saúde , Hospitais
9.
Crit Rev Food Sci Nutr ; 60(16): 2676-2690, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32876477

RESUMO

In recent years, applications of cold plasma treatments have shown high efficiency in sterilization of fresh fruit and vegetables. With encouraging results, development of this technique focuses on influences of cold plasma on the quality attributes of these fresh produce. More studies found that the quality attributes are maintained in an acceptable range or can even be improved under certain plasma treatment conditions. This review provides an overview of the multiple effects of cold plasma on the fresh produce, in terms of physical, chemical and physiological aspects. Besides, the possible mechanisms of how plasma influences these quality attributes is elaborated, which is useful for further modification and improvement of the plasma technology, so that quality enhancement and shelf life extension can be achieved. Future trends in the development of cold plasma technology are also presented. Cold plasma treatment is a potential technology for treating fresh fruit and vegetables to enhance their quality and extend their shelf life. However, knowledge of the effects of cold plasma on the quality changes of fresh fruit and vegetables is still limited. Therefore, there is a need for future studies to understand the mechanisms of plasma effects on controlling the interactions between plasma and food products in order to realize the early adoption of the technology to the food industry.


Assuntos
Conservação de Alimentos , Frutas , Gases em Plasma , Verduras , Frutas/química , Frutas/fisiologia , Esterilização , Verduras/química , Verduras/fisiologia
10.
Chemosphere ; 254: 126831, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32957272

RESUMO

The problem of bacterial antibiotic resistance has attracted considerable research attention, and the effects of water treatment on antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) are being increasingly investigated. As an indispensable part of the water treatment process, disinfection plays an important role in controlling antibiotic resistance. At present, there were many studies on the effects of conventional and new sterilization methods on ARB and ARGs. However, there is a lack of literature relating to the limitations of conventional methods and analysis of new techniques. Therefore, this review focuses on analyzing the deficiencies of conventional disinfection and the development of new methods for antibiotic resistance control to guide future research. Firstly, we analyzed the effects and drawbacks of conventional disinfection methods, such as chlorine (Cl), ultraviolet (UV) and ozone on antibiotic resistance control. Secondly, we discuss the research progress and shortcomings of new sterilization methods in antibiotic resistance. Finally, we propose suggestions for future research directions. There is an urgent need for new effective and low-cost sterilization methods. Disinfection via UV and chlorine in combination, UV/chlorine showed greater potential for controlling ARGs.


Assuntos
Desinfecção/métodos , Esterilização/métodos , Purificação da Água/métodos , Cloro/farmacologia , Desinfecção/tendências , Farmacorresistência Bacteriana/genética , Esterilização/tendências , Raios Ultravioleta
11.
PLoS Negl Trop Dis ; 14(8): e0008669, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32866146

RESUMO

Exposure of adult mosquitoes to pyriproxyfen (PPF), an analog of insect juvenile hormone (JH), has shown promise to effectively sterilize female mosquitoes. However, the underlying mechanisms of the PPF-induced decrease in mosquito fecundity are largely unknown. We performed a comprehensive study to dissect the mode of PPF action in Aedes aegypti mosquitoes. Exposure to PPF prompted the overgrowth of primary follicles in sugar-fed Ae. aegypti females but blocked the development of primary follicles at Christopher's Stage III after blood feeding. Secondary follicles were precociously activated in PPF-treated mosquitoes. Moreover, PPF substantially altered the expression of many genes that are essential for mosquito physiology and oocyte development in the fat body and ovary. In particular, many metabolic genes were differentially expressed in response to PPF treatment, thereby affecting the mobilization and utilization of energy reserves. Furthermore, PPF treatment on the previtellogenic female adults considerably modified mosquito responses to JH and 20-hydroxyecdysone (20E), two major hormones that govern mosquito reproduction. Krüppel homolog 1, a JH-inducible transcriptional regulator, showed consistently elevated expression after PPF exposure. Conversely, PPF upregulated the expression of several key players of the 20E regulatory cascades, including HR3 and E75A, in the previtellogenic stage. After blood-feeding, the expression of these 20E response genes was significantly weaker in PPF-treated mosquitoes than the solvent-treated control groups. RNAi-mediated knockdown of the Methoprene-tolerant (Met) protein, the JH receptor, partially rescued the impaired follicular development after PPF exposure and substantially increased the hatching of the eggs produced by PPF-treated female mosquitoes. Thus, the results suggested that PPF relied on Met to exert its sterilizing effects on female mosquitoes. In summary, this study finds that PPF exposure disturbs normal hormonal responses and metabolism in Ae. aegypti, shedding light on the molecular targets and the downstream signaling pathways activated by PPF.


Assuntos
Aedes/efeitos dos fármacos , Culicidae/efeitos dos fármacos , Inseticidas/farmacologia , Metoprene/metabolismo , Esterilização , Animais , Ecdisterona/farmacologia , Corpo Adiposo/crescimento & desenvolvimento , Feminino , Glicogênio/metabolismo , Proteínas de Insetos/genética , Hormônios Juvenis/farmacologia , Ovário/crescimento & desenvolvimento , Piridinas , Interferência de RNA , Triglicerídeos/metabolismo
12.
AAPS PharmSciTech ; 21(7): 247, 2020 Aug 30.
Artigo em Inglês | MEDLINE | ID: mdl-32862255

RESUMO

Norepinephrine is a potent α-sympathomimetic drug which plays an important role in the acute treatment of hypotension and shock. Commercially available norepinephrine solutions contain sodium metabisulfite (Na2S2O5) as an antioxidant. However, prefilled cyclic olefin polymer syringes are not compatible with sodium metabisulfite. The aim of this study was to develop a new formulation of 0.1-mg/mL norepinephrine solution without sodium metabisulfite which is chemically stable and sterile and can be stored in prefilled polymer syringes. Formulation studies were performed with 0.1-mg/mL norepinephrine solution with 0, 0.05, or 0.1% ascorbic acid added as antioxidant. The syringes were filled under nitrogen gassing, stored at 20 ± 5°C, and protected from daylight. Based on the formulation test results, the final formulation was defined and stability testing at 20 ± 5°C was performed measuring norepinephrine concentration, pH, clarity, color of the solution, subvisible particles, and sterility at time intervals up to 12 months. The norepinephrine concentrations at t = 22 weeks were 100.4%, 95.4%, and 92.2% for the formulations with no ascorbic acid and with 0.05% and 0.10% ascorbic acid, respectively. Three batches for the stability study were produced containing norepinephrine, sodium edetate, sodium chloride, and water for injections filled under nitrogen gassing and stored at 20 ± 5°C. Norepinephrine concentrations were respectively 98.8%, 98.6%, and 99.3% for batches 1, 2, and 3 at t = 12 months. It can be concluded that norepinephrine (0.1 mg/mL) solution without metabisulfite is stable for at least 12 months at room temperature when protected from daylight.


Assuntos
Alcenos/química , Antioxidantes/química , Norepinefrina/química , Esterilização/métodos , Seringas , Alcenos/análise , Antioxidantes/análise , Estabilidade de Medicamentos , Armazenamento de Medicamentos/métodos , Armazenamento de Medicamentos/normas , Injeções , Norepinefrina/análise , Soluções Farmacêuticas/análise , Soluções Farmacêuticas/química , Seringas/normas
13.
Artigo em Inglês | MEDLINE | ID: mdl-32784414

RESUMO

SARS-CoV-2, and several other microorganisms, may be present in nasopharyngeal and salivary secretions in patients treated in dental practices, so an appropriate clinical behavior is required in order to avoid the dangerous spread of infections. COVID-19 could also be spread when patients touches a contaminated surface with infected droplets and then touch their nose, mouth, or eyes. It is time to consider a dental practice quite similar to a hospital surgery room, where particular attention should be addressed to problems related to the spreading of infections due to air and surface contamination. The effectiveness of conventional cleaning and disinfection procedures may be limited by several factors; first of all, human operator dependence seems to be the weak aspect of all procedures. The improvement of these conventional methods requires the modification of human behavior, which is difficult to achieve and sustain. As alternative sterilization methods, there are some that do not depend on the operator, because they are based on devices that perform the entire procedure on their own, with minimal human intervention. In conclusion, continued efforts to improve the traditional manual disinfection of surfaces are needed, so dentists should consider combining the use of proper disinfectants and no-touch decontamination technologies to improve sterilization procedures.


Assuntos
Infecções por Coronavirus/epidemiologia , Consultórios Odontológicos/métodos , Pneumonia Viral/epidemiologia , Esterilização/métodos , Betacoronavirus , Consultórios Odontológicos/normas , Desinfecção/métodos , Desinfecção/normas , Fidelidade a Diretrizes , Humanos , Pandemias , Guias de Prática Clínica como Assunto , Esterilização/normas
14.
PLoS One ; 15(8): e0235948, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32785216

RESUMO

INTRODUCTION: Surgical site infection is one of the most severe complications of surgical treatments. However, the optimal procedure to prevent such infections remains uninvestigated. Ultraviolet radiation C (UVC) with a short wavelength has a high bactericidal effect; however, it is cytotoxic. Nonetheless, given that UVC with a wavelength of 222 nm reaches only the stratum corneum, it does not affect the skin cells. This study aimed to investigate the safety of 222-nm UVC irradiation and to examine its skin sterilization effect in healthy volunteers. METHODS: This trial was conducted on 20 healthy volunteers. The back of the subject was irradiated with 222-nm UVC at 50-500 mJ/cm2, and the induced erythema (redness of skin) was evaluated. Subsequently, the back was irradiated with a maximum amount of UVC not causing erythema, and the skin swabs before and after the irradiation were cultured. The number of colonies formed after 24 hours was measured. In addition, cyclobutene pyrimidine dimer (CPD) as an indicator of DNA damage was measured using skin tissues of the nonirradiated and irradiated regions. RESULTS: All subjects experienced no erythema at all doses. The back of the subject was irradiated at 500 mJ/cm2, and the number of bacterial colonies in the skin swab culture was significantly decreased by 222-nm UVC irradiation. The CPD amount produced in the irradiated region was slightly but significantly higher than that of the non-irradiated region. CONCLUSION: A 222-nm UVC at 500 mJ/cm2 was a safe irradiation dose and possessed bactericidal effects. In the future, 222-nm UVC irradiation is expected to contribute to the prevention of perioperative infection.


Assuntos
Dano ao DNA/efeitos da radiação , Microbiota/efeitos da radiação , Pele/efeitos da radiação , Esterilização/métodos , Raios Ultravioleta/efeitos adversos , Adulto , Dorso , Biópsia , Contagem de Colônia Microbiana , Eritema/diagnóstico , Eritema/etiologia , Voluntários Saudáveis , Humanos , Masculino , Dímeros de Pirimidina/análise , Dímeros de Pirimidina/efeitos da radiação , Pele/microbiologia , Infecção da Ferida Cirúrgica/microbiologia , Infecção da Ferida Cirúrgica/prevenção & controle , Resultado do Tratamento
15.
Pediatr Neurol ; 111: 87, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32861581
16.
Dermatol Online J ; 26(5)2020 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-32621711

RESUMO

Vertical surgical sites or those on reclining patients often present a challenge when establishing and securing a sterile field. The drape or towel most proximal to the physician is often vertically oriented. The forces of gravity and movements of surgery can shift or detach this vertical drape. Sterile clamps are not always available or are needed for securing other instruments. We present a method to secure this vulnerable drape using a central fenestrated adherent drape.


Assuntos
Procedimentos Cirúrgicos Dermatológicos/instrumentação , Equipamentos Cirúrgicos , Humanos , Esterilização
17.
Dig Endosc ; 32(7): 1105-1110, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32702176

RESUMO

Endoscopy is widely used as a clinical diagnosis and treatment method for certain hepatobiliary and pancreatic diseases. However, due to the distinctive epidemiological characteristics of severe acute respiratory syndrome coronavirus 2, the virus causing coronavirus disease-2019 (COVID-19), healthcare providers are exposed to the patient's respiratory and gastrointestinal fluids, rendering endoscopy a high risk for transmitting a nosocomial infection. This article introduces preventive measures for endoscopic treatment enacted in our medical center during COVID-19, including the adjustment of indications, the application of endoscope protective equipment, the design and application of endoscopic masks and splash-proof films, and novel recommendations for bedside endoscope pre-sterilization.


Assuntos
Infecções por Coronavirus/prevenção & controle , Infecção Hospitalar/prevenção & controle , Transmissão de Doença Infecciosa/prevenção & controle , Endoscópios/normas , Endoscopia Gastrointestinal/normas , Controle de Infecções/normas , Máscaras , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Microbiologia do Ar , Betacoronavirus , China/epidemiologia , Infecções por Coronavirus/epidemiologia , Contaminação de Equipamentos/prevenção & controle , Unidades Hospitalares/normas , Humanos , Pneumonia Viral/epidemiologia , Esterilização
18.
BMJ Open ; 10(7): e039120, 2020 07 07.
Artigo em Inglês | MEDLINE | ID: mdl-32641368

RESUMO

OBJECTIVE: To develop and test a new reusable, sterilisable N95 filtering facepiece respirator (FFR)-comparable face mask, known as the Injection Molded Autoclavable, Scalable, Conformable (iMASC) system, given the dire need for personal protective equipment within healthcare settings during the COVID-19 pandemic. DESIGN: Single-arm feasibility study. SETTING: Emergency department and outpatient oncology clinic. PARTICIPANTS: Healthcare workers who have previously undergone N95 fit testing. INTERVENTIONS: Fit testing of new iMASC system. PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcome is success of fit testing using an Occupational Safety and Health Administration (OSHA)-approved testing method, and secondary outcomes are user experience with fit, breathability and filter replacement. RESULTS: Twenty-four subjects were recruited to undergo fit testing, and the average age of subjects was 41 years (range of 21-65 years) with an average body mass index of 26.5 kg/m2. The breakdown of participants by profession was 46% nurses (n=11), 21% attending physicians (n=5), 21% resident physicians (n=5) and 12% technicians (n=3). Of these participants, four did not perform the fit testing due to the inability to detect saccharin solution on premask placement sensitivity test, lack of time and inability to place mask over hair. All participants (n=20) who performed the fit test were successfully fitted for the iMASC system using an OSHA-approved testing method. User experience with the iMASC system, as evaluated using a Likert scale with a score of 1 indicating excellent and a score of 5 indicating very poor, demonstrated an average fit score of 1.75, breathability of 1.6, and ease of replacing the filter on the mask was scored on average as 2.05. CONCLUSIONS: The iMASC system was shown to successfully fit multiple different face sizes and shapes using an OSHA-approved testing method. These data support further certification testing needed for use in the healthcare setting.


Assuntos
Infecções por Coronavirus/prevenção & controle , Desenho de Equipamento , Transmissão de Doença Infecciosa do Paciente para o Profissional/prevenção & controle , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Dispositivos de Proteção Respiratória , Elastômeros de Silicone , Adulto , Idoso , Pessoal Técnico de Saúde , Betacoronavirus , Infecções por Coronavirus/transmissão , Reutilização de Equipamento , Estudos de Viabilidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Enfermeiras e Enfermeiros , Médicos , Pneumonia Viral/transmissão , Estudos Prospectivos , Esterilização , Adulto Jovem
19.
Zhongguo Yi Liao Qi Xie Za Zhi ; 44(3): 236-241, 2020 Mar 08.
Artigo em Chinês | MEDLINE | ID: mdl-32621432

RESUMO

Traditional medical device sterilization processes are mature, but there are constraints when using on medical devices by new materials. With increasing environmental concerns, using of ethylene oxide sterilization has been limited by global environmental protection administrations. Exploring new sterilization methods for medical devices is urgently needed. This paper reviews the supercritical carbon dioxide sterilization technology by arranging the exploratory work of industry researchers. In the paper, we introduce the theory of supercritical carbon dioxide sterilization technology, microbial inactivation ability, material influence research and sterilization equipment. Then we discuss the concerns and possibilities of the technology applied to the medical device industry basing on the good manufacturing practices.


Assuntos
Esterilização , Dióxido de Carbono
20.
Acta Odontol Latinoam ; 33(1): 45-49, 2020 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-32621599

RESUMO

The gutta-percha cones used in endodontic treatment are produced in aseptic conditions and their composition includes zinc oxide, which is responsible for antibacterial activity. However, there is the possibility of microbial contamination by manipulation, aerosol or during storage. Although several chemical agents have been tested for their decontamination, there is no consensus on the best disinfection protocol to be used. The aim of this study was to evaluate the decontamination of gutta-percha cones contaminated with the bacteria Enterococcus faecalis, by using chlorhexidine digluconate (CHX) and sodium hypochlorite (NaClO) at different concentrations for short exposure times. For this purpose, gutta-percha cones (size 40) were selected at random from a sealed box and immersed for 1 min in a microbial suspension. Then they were immersed in specific Petri dishes for different groups containing: CHX 2%, NaClO 1% or NaClO 2.5% for 30 s or 1 min, and subsequently placed in tubes containing BHI broth. After incubating the tubes for 48 h, it was observed that 1% and 2.5% NaClO and 2% CHX were effective for decontaminating the cones at those exposure time intervals. Microbial growth was detected in one of the replicates of the group with CHX applied for 30 s. To prevent the possibility of failures at this stage, the exposure time of gutta-percha cones to the decontaminating agent should not be reduced.


Assuntos
Clorexidina/análogos & derivados , Descontaminação/métodos , Desinfetantes de Equipamento Odontológico/farmacologia , Enterococcus faecalis/efeitos dos fármacos , Guta-Percha , Irrigantes do Canal Radicular/farmacologia , Hipoclorito de Sódio/farmacologia , Esterilização/métodos , Anti-Infecciosos Locais , Clorexidina/farmacologia , Desinfetantes de Equipamento Odontológico/administração & dosagem , Enterococcus faecalis/isolamento & purificação , Contaminação de Equipamentos/prevenção & controle , Humanos , Materiais Restauradores do Canal Radicular , Irrigantes do Canal Radicular/administração & dosagem , Hipoclorito de Sódio/administração & dosagem
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