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1.
Technol Cult ; 63(2): 326-348, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35531801

RESUMO

Japan's Meiji oligarchs put a premium on technologies that projected "civilization" and "modernity" and operated under the assumption that industrial technologies could be operationalized reasonably promptly. Their faith flew in the face of production experience. The case of metallurgical coke manufacturing offers an example of what happened when imported technological systems dead-ended on the fctory floor. Examining the production records of a Meiji-era chemical start-up, this article brings to focus the scope and scale of the creative labor needed to make imported technologies work on the ground. In so doing, it showcases innovative forces that formed the fabric of Japan's early industrialization as a corrective to the much-criticized but resilient notion that the country's industrial takeoff was enabled largely by technology transfer and local appropriation. By highlighting the creativity involved in designing coal inputs, this article opens new perspectives on the history of coals in East Asia.


Assuntos
Carvão Mineral , Aço , Extremo Oriente , Indústrias , Japão
2.
PLoS One ; 17(5): e0268195, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35511880

RESUMO

Moisture evolution in Central Asia including Northwest China shows less similarity with its surroundings and attracts a growing number of studies. In this study, a well-dated thick lacustrine sequence is chosen in Northwest China and detailed geochemical analysis is conducted during the Middle Miocene Climate Transition (MMCT, 14-11 Ma). The multi-proxy records (Na2O/Al2O3, CIA, Rb/Sr) revealed that chemical weathering was the strongest during 11.85-11 Ma, the coldest period in 14-11 Ma as evidenced by the global deep-sea oxygen isotope records. Accordingly, we conclude that global climate cooled during MMCT and reached the coldest during 11.85-11 Ma. Thus, the westerly circulation became the strongest during this period, which brought more water vapor to Northwest China and the chemical weathering was significantly improved. On the other hand, the significant decrease in temperature led to the marked weakening of evapotranspiration, and thus the effective humidity was relatively increased. Both aspects contribute greatly to the significant enhancement of chemical weathering in eastern Central Asia. This weathering history of the sediments in the northeastern Tibetan Plateau is of great scientific significance to understanding tectonism and climate change in Asia during MMCT.


Assuntos
Mudança Climática , Ásia , China , Extremo Oriente , Temperatura
3.
Sci Rep ; 12(1): 6932, 2022 Apr 28.
Artigo em Inglês | MEDLINE | ID: mdl-35484195

RESUMO

This national administrative investigation of Republic of Korea compared the risk of attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders(ASD) in preschool amblyopic children and identified factors that possibly mediate this association. After propensity score (PS) matching, 7762 amblyopic children and 31,030 non-amblyopic children were included. Amblyopia was associated with ADHD (aOR:1.687; 95% CI 1.444, 1.970) but not with ASD (aOR: 0.591; 95% CI 0.341, 1.026). Fine motor skill impairment was a mediating factor in association of amblyopia with ADHD, accounting for 4.2% (95% CI 1.7, 8.0). In conclusion, amblyopic children have a greater risk of ADHD, and deficits in fine motor skills mediate this association. We suggest increased attention given to fine motor skill underdevelopment in amblyopic children to prevent the development of ADHD.


Assuntos
Ambliopia , Transtorno do Deficit de Atenção com Hiperatividade , Ambliopia/epidemiologia , Transtorno do Deficit de Atenção com Hiperatividade/complicações , Transtorno do Deficit de Atenção com Hiperatividade/epidemiologia , Criança , Pré-Escolar , Estudos de Coortes , Extremo Oriente , Humanos , Destreza Motora
4.
BMJ Case Rep ; 15(4)2022 Apr 07.
Artigo em Inglês | MEDLINE | ID: mdl-35393273

RESUMO

Menkes disease (MD) is an X linked recessive multi-systemic disorder of copper metabolism, resulting from an ATP7A gene mutation. We report a male infant aged 4 months who presented with kinky hair, hypopigmented skin, epilepsy and delayed development. Magnetic resonance imaging (MRI) of brain demonstrated multiple tortuosities of intracranial vessels and brain atrophy. Investigation had showed markedly decreased serum copper and ceruloplasmin. The novel c.2172+1G>T splice-site mutation in the ATP7A gene confirmed MD. He was treated with subcutaneous administration of locally prepared copper-histidine (Cu-His). Following the therapy, hair manifestation was restored and serum ceruloplasmin was normalised 1 month later. Despite the treatment, epilepsy, neurodevelopment and osteoporosis still progressed. He died from severe respiratory tract infection at the age of 9.5 months. These findings suggest that the benefit of Cu-His in our case is limited which might be related to severe presentations and degree of ATP7A mutation.


Assuntos
Proteínas de Transporte de Cátions , Epilepsia , Síndrome dos Cabelos Torcidos , Adenosina Trifosfatases/genética , Adenosina Trifosfatases/metabolismo , Proteínas de Transporte de Cátions/genética , Ceruloplasmina/análise , Cobre , ATPases Transportadoras de Cobre/genética , ATPases Transportadoras de Cobre/metabolismo , Extremo Oriente , Histidina/análogos & derivados , Histidina/genética , Humanos , Lactente , Masculino , Síndrome dos Cabelos Torcidos/tratamento farmacológico , Síndrome dos Cabelos Torcidos/genética , Mutação , Compostos Organometálicos , Fragmentos de Peptídeos/metabolismo
5.
Environ Monit Assess ; 194(5): 358, 2022 Apr 12.
Artigo em Inglês | MEDLINE | ID: mdl-35412155

RESUMO

The aim of this research was the analysis of the effect of a dam height raise on the water quality of a tropical reservoir used for drinking water purposes in South East Asia. Analyses of iron, manganese, pH and ammonia were performed over a 5-year period from daily water sampling at the reservoir. In addition, high-frequency monitoring data of nitrate, ammonium, pH and blue-green algae were obtained using a monitoring probe. The results showed that due to the raising of the reservoir water level, previously oxic sediments became submerged, triggering an increase in iron and manganese in particular due to the establishment of reducing conditions. Manganese concentrations with values up to 4 mg L-1 are now exceeding guideline values. The analysis strongly indicated that both iron and manganese have a seasonal component with higher iron and manganese concentrations during the wet season. Over a three-year period afterwards, concentrations did not go back to pre-raise levels. The change in water quality was accompanied by a change in pH from previous values of around 5 to pH values of around 6.5. Geochemical simulations confirmed the theory that the increasing concentrations of iron and manganese are due to the dissolution of MnO2 and ferric oxyhydroxides oxidising organic matter in the process. This study showed that changes in reservoir water levels with the establishment of reducing conditions can have long-term effects on the water quality of a reservoir.


Assuntos
Manganês , Poluentes Químicos da Água , Monitoramento Ambiental , Extremo Oriente , Ferro/análise , Manganês/análise , Compostos de Manganês/análise , Óxidos/análise , Poluentes Químicos da Água/análise
6.
Sci Rep ; 12(1): 5546, 2022 04 01.
Artigo em Inglês | MEDLINE | ID: mdl-35365703

RESUMO

Ichthyopterygia is a major clade of reptiles that colonized the ocean after the end-Permian mass extinction, with the oldest fossil records found in early Spathian substage (late Olenekian, late Early Triassic) strata in the western USA. Here, we describe reptilian remains found in situ in the early Spathian Neocolumbites insignis ammonoid zone of South Primorye in the Russian Far East. Specimen NSM PV 23854 comprises fragmentary axial elements exhibiting a combination of morphological characteristics typical of Ichthyopterygia. The cylindrical centra suggest that the specimen represents a basal ichthyopterygian, and its size is comparable to that of Utatsusaurus. Specimen NSM PV 24995 is represented by a single limb bone, which is tentatively identified as an ichthyopterygian humerus. With a body length of approximately 5 m estimated from the humeral length, NSM PV 24995 represents one of the largest specimens of early Spathian marine reptiles known to date. Such size variation among the earliest ichthyopterygians might suggest an explosive diversification in size immediately after the end-Permian mass extinction. Both vertebrae and humerus specimens exhibit an extremely cancellous inner structure, suggesting a high degree of aquatic adaptation in ichthyopterygians, despite their short history of evolution in the ocean.


Assuntos
Evolução Biológica , Fósseis , Animais , Extremo Oriente , Filogenia , Répteis/anatomia & histologia
7.
Sci Rep ; 12(1): 5539, 2022 04 01.
Artigo em Inglês | MEDLINE | ID: mdl-35365707

RESUMO

Changes in the aerosol composition of sulfate (SO42-) and nitrate (NO3-) from 2012 to 2019 have been captured as a paradigm shift in the region downwind of China. Specifically, SO42- dramatically decreased and NO3- dramatically increased over downwind locations such as western Japan due to the faster reduction of SO2 emissions than NOx emissions and the almost constant trend of NH3 emissions from China. Emissions from China sharply decreased during COVID-19 lockdowns in February-March 2020, after which China's economic situation seemed to recover going into 2021. Given this substantial change in Chinese emissions, it is necessary to clarify the impact of long-range PM2.5 transport into the leeward of East Asia. In this study, ground-based aerosol compositions observed at three sites in western Japan were analysed. The concentrations of PM2.5, SO42- and NO3- decreased in 2020 (during COVID-19) compared with 2018-2019 (before COVID-19). In 2021 (after COVID-19), PM2.5 and NO3- increased and SO42- was unchanged. This suggests the returning long-range PM2.5 transport in 2021. From numerical simulations, the status of Chinese emissions during COVID-19 did not explain this returning impact in 2021. This study shows that the status of Chinese emissions in 2021 recovered to that before COVID-19.


Assuntos
Poluentes Atmosféricos , COVID-19 , Poluentes Atmosféricos/análise , COVID-19/epidemiologia , China/epidemiologia , Controle de Doenças Transmissíveis , Monitoramento Ambiental , Extremo Oriente/epidemiologia , Humanos , Pandemias , Material Particulado/análise
8.
PLoS One ; 17(4): e0264660, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35421097

RESUMO

Global changes may direct species expansion away from their current range. When such an expansion occurs, and the species colonizes a new region, it is important to monitor the habitat used by the species and utilize the information to updated management strategies. Water deer (Hydropotes inermis) is listed as Vulnerable species in IUCN Red List and is restricted to east central China and the Korean Peninsula. Since 2017, water deer has expanded its range towards northeast China and the Russian Far East. The objective of our study is to provide support for a better understanding of habitat use and provide suggestions for developing conservation strategy. We collected occurrence data in northeast China and the Russian Far East during 2017-2021. We used MaxEnt to predict habitat suitability for water deer and applied Circuitscape to determine possible dispersal routes for the species. We used seven environmental variables, viz., altitude, slope, aspect, distance to built-up area, distance to water source, distance to cropland and distance to roads for habitat suitability prediction. We chose the MaxEnt model (AICc = 2572.86) suitable for our data with the AUC value result of 0.935±0.014. There is good quality habitat for water deer in the boundary area of the Yalu and Tumen River estuaries between China, North Korea, and the Russian Far East, as well as the east and west regions of the Korean Peninsula. We identified three main suitable habitat patches, two of them located in east (NK2) and west (NK3) North Korea, and one in the newly colonized area downstream of the Tumen River along the border of China, Russia, and North Korea (TM1). Elevation, distance to cropland and water sources, and presence of wetlands were the variables that positively contributed to modelling the suitable habitats. Two possible dispersal routes were determined using the circuit theory, one was across the area from North Korea to the downstream Tumen transboundary region (Route B), and the other was across North Korea to the boundary region in China and along the tiger national park in northern China (Route A). A series of protected areas in North Korea, China, and Russia may support the dispersal of water deer. From the study on water deer dispersal, we can understand the existing ecological network in northeast Asia, which will benefit the whole landscape and biodiversity conservation. However, there are many threats present, and there is need for continued monitoring inside and outside the protected areas. Information sharing with stakeholders and carrying out local communities awareness activities are important. The establishment of a Northeast Asia landscape conservation network would help establish monitoring and conservation planning at a broad scale, and this study provides an example of the need for such a network.


Assuntos
Cervos , Animais , China , Ecossistema , Extremo Oriente , República da Coreia , Água
9.
Zootaxa ; 5100(2): 296-300, 2022 Feb 18.
Artigo em Inglês | MEDLINE | ID: mdl-35391073

RESUMO

Dendrolasiophilus subitus sp. nov. from the Russian Far East is described and illustrated. Some nomenclatural notes on the genus Dendrolasiophilus Nomura, 2010 are given.


Assuntos
Besouros , Distribuição Animal , Animais , Extremo Oriente , Federação Russa
10.
Zootaxa ; 5120(4): 573-585, 2022 Mar 29.
Artigo em Inglês | MEDLINE | ID: mdl-35391148

RESUMO

Ischnura elegans malikovae ssp. n. is described from the southern Far East of Russia (type locality: Russia, Primorskiy Kray, Pozharskiy District, Luchegorsk Town, the Luchegorsk Reservoir). Reconsideration of literature suggested it to broadly range in East Asia including Korea, Japan (Hokkaido and northernmost Honshu), north and north-east China and to be hitherto mistaken for Ischnura elegans elegans (Vander Linden, 1820) in Japan. The main difference of the new subspecies from I. e. elegans is the male paraprocts that are about 1.5 times shorter and scarcely divaricating in dorsal view and directed obliquely upward in lateral view. Ischnura elegans ebneri Schmidt, 1938 is reconsidered as the presumably Anterior Asian subspecies characterised by scarcely or not diverging male paraprocts in dorsal view, versus strongly diverging in I. e. elegans. Based on scarce information in the literature, I. elegans marquardti Schmidt, 1938 is supposed to be a junior synonym of I. elegans ordosi Bartenev, 1912 stat. rev., which is suggested to be an eastern Central Asian subspecies characterised by an incised prothoracic process in males.


Assuntos
Odonatos , Animais , Extremo Oriente , Masculino
11.
Zootaxa ; 5120(2): 151-197, 2022 Mar 25.
Artigo em Inglês | MEDLINE | ID: mdl-35391175

RESUMO

The type material of spider wasps deposited in the Federal Scientific Center of the East Asia Terrestrial Biodiversity, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russia is catalogued. In total, this includes 305 primary type specimens (31 holotypes and 274 paratypes) belonging to 62 species and 1 subspecies, described between 1962 and 2019 from Russia, Tajikistan, China, South Korea, Japan, Laos, Indonesia, and Sri Lanka. All 31 holotypes are illustrated with color photographs and black-and-white drawings. Photographs of the habitus, head, hypopygium and genitalia of three holotypes and photographs of the habitus and head of 23 holotypes are presented for the first time. References to the original description, type localities, current status, and distribution of taxa are given. Data on the labels of holotypes and paratypes with clarifications and English translations are provided.


Assuntos
Himenópteros , Vespas , Animais , Biodiversidade , Extremo Oriente , Federação Russa
12.
Environ Sci Technol ; 56(7): 4282-4294, 2022 Apr 05.
Artigo em Inglês | MEDLINE | ID: mdl-35293723

RESUMO

Low birthweight (LBW) is a worldwide public health concern, while the global burden of LBW attributable to endocrine-disrupting chemicals, such as per- and polyfluoroalkyl substances (PFAS), has not yet been evaluated. Here, we established a large dataset for the biomonitoring of seven representative congeners of PFAS by examining data from 2325 publications. Global exposure to perfluorooctanesulfonic acid (PFOS) was the highest, followed by perfluorohexanesulfonic acid (PFHxS) and perfluorooctanoic acid (PFOA). Spatiotemporal exposure to PFAS varied considerably, with daily intake estimated in the range of 0.01-1.7 ng/kg/day. Moreover, decreasing trends in PFOS, PFHxS, and PFOA exposure were noted in most regions of the world over the past two decades, but such trends were not observed for other PFAS with long carbon chains, especially in East Asia. Furthermore, we estimated that human exposure to PFOA contributed to approximately 461,635 (95% confidence interval: 57,418 to 854,645) cases per year of LBW during the past two decades, predominantly from Asian regions. Although our estimation may be constrained by uncertainties from the dose-response curve and data availability, this study has unveiled that PFAS might be a contributor to global LBW prevalence during 2000-2019, supporting continuous actions to mitigate PFAS contamination.


Assuntos
Ácidos Alcanossulfônicos , Disruptores Endócrinos , Poluentes Ambientais , Fluorcarbonetos , Ácidos Alcanossulfônicos/análise , Peso ao Nascer , Carbono , Extremo Oriente , Fluorcarbonetos/análise , Humanos
13.
Sci Rep ; 12(1): 5065, 2022 03 24.
Artigo em Inglês | MEDLINE | ID: mdl-35332171

RESUMO

The lime leaf-miner, Phyllonorycter issikii is an invasive micromoth with an unusually higher number of haplotypes in the invaded area (Europe, Western Siberia) compared to its putative native region (East Asia). The origin of the genetic diversity in the neocolonized region remains unclear. We surveyed over 15 thousand herbarium specimens of lime trees (Tilia spp.) collected across the Palearctic over a period of 252 years (1764-2016) looking for preserved larvae within the archival leaf mines. We found 203 herbarium specimens with leaf mines of Ph. issikii collected in East Asia, one of them dating back to 1830, i.e. 133 years before the description of the species. In contrast, only 22 herbarium specimens collected in the West Palearctic in the last three decades (1987-2015) carried leaf mines. DNA barcoding of archival specimens revealed 32 haplotypes out of which 23 were novel (not known from modern populations) and found exclusively in East Asia. Six haplotypes are shared between both native and invaded areas and only two were responsible for the recent invasion of the Western Palearctic. The remarkable number of newly discovered haplotypes in archival populations supports East Asia as the native region and the source area of invasion.


Assuntos
Mariposas , Animais , Código de Barras de DNA Taxonômico , Extremo Oriente , Variação Genética , Haplótipos , Mariposas/genética , Filogenia , Árvores
14.
PLoS One ; 17(3): e0265329, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35294491

RESUMO

Late Pleistocene hunter-gatherers in East Asia adopted pottery, yet the ability to reconstruct circulation, mobility, and exchange has been hampered, in part, due to problematic regional geochronology. The driving forces behind pottery adoption is unclear. The purpose of this study is to test our results of the first systematic petrographic pottery sourcing from the pre-Younger Dryas by utilizing neutron activation analysis. We examine samples from the Sankauyama I site on Tanegashima Island, southern Japan, dating to the Incipient Jomon, ca. 14,000/13,500-12,800 cal BP, with a well-defined geochronology. Our NAA results corroborate with the petrographic study suggesting that pottery was mainly produced in-situ, but some vessels were transported long distances from another island. Changing from high mobility, sedentary Incipient Jomon foragers made pottery, occasionally investing in long-distance ceramic vessel transportation and exchange likely involving ocean crossing. This may be associated with a risk-buffering strategy in the context of rising sea levels and isolation of Tanegashima.


Assuntos
Arqueologia , Cerâmica , Extremo Oriente , Japão , Análise de Ativação de Nêutrons
15.
Global Health ; 18(1): 33, 2022 03 18.
Artigo em Inglês | MEDLINE | ID: mdl-35303902

RESUMO

BACKGROUND: Weak governance over public sector pharmaceutical policy and practice limits access to essential medicines, inflates pharmaceutical prices, and wastes scarce health system resources. Pharmaceutical systems are technically complex and involve extensive interactions between the private and public sectors. For members of public sector pharmaceutical committees, relationships with the private sector can result in conflicts of interest, which may introduce commercial biases into decision-making, potentially compromising public health objectives and health system sustainability. We conducted a descriptive, qualitative study of conflict of interest policies and practices in the public pharmaceutical sector in ten countries in the World Health Organization (WHO) South-East Asia Region (SEAR) (Bangladesh, Bhutan, India, Indonesia, Maldives, Myanmar, Nepal, Sri Lanka, Thailand, and Timor-Leste) between September 2020 and March 2021. RESULTS: We identified 45 policy and regulatory documents and triangulated documentary data with 21 expert interviews. Key informants articulated very different governance priorities and conflict of interest concerns depending on the features of their country's pharmaceutical industry, market size, and national economic objectives related to the domestic pharmaceutical industry. Public sector pharmaceutical policies and regulations consistently contained provisions for pharmaceutical committee members to disclose relevant interests, but contained little detail about what should be declared, when, and how often, nor whether disclosures are evaluated and by whom. Processes for preventing or managing conflicts of interest were less well developed than those for disclosure except for a few key procurement processes. Where processes for managing conflicts of interest were specified, the dominant strategy was to recuse committee members with a conflict of interest from relevant work. Policies rarely specified that committee members should divest or otherwise be free from conflicts of interest. CONCLUSIONS: Robust processes for conflict of interest prevention and management could ensure the integrity of decision-making and build public trust in pharmaceutical processes to achieve public health objectives. Upstream approaches including supportive legislative frameworks, the creation of oversight bodies, and strengthening regulatory institutions can also contribute to building cultures of transparency, accountability, and trust.


Assuntos
Revelação , Setor Público , Conflito de Interesses , Extremo Oriente , Humanos , Preparações Farmacêuticas , Políticas , Responsabilidade Social , Organização Mundial da Saúde
16.
Sci Rep ; 12(1): 5366, 2022 03 30.
Artigo em Inglês | MEDLINE | ID: mdl-35354875

RESUMO

The East Asian countries have experienced heavy rainfalls in boreal summer 2020. Here, we investigate the dynamical processes driving the rainfall extremes in East Asia during July and August. The Indian Ocean basin warming in June can be responsible for the anticyclonic anomalies in the western North Pacific (WNP), which modulate the zonally-elongated rainfalls in East Asia during July through an atmospheric Rossby wave train. In August, the East Asian rainfall increase is also related to the anticyclonic anomalies in the subtropical WNP, although it is located further north. The north tropical Atlantic warming in June partly contributes to the subtropical WNP rainfall decrease in August through a subtropical teleconnection. Then the subtropical WNP rainfall decrease drives the local anticyclonic anomalies that cause the rainfall increase in East Asia during August. The tropical Indian Ocean anomalously warmed in June and the subtropical WNP rainfall decreased in August 2020, which played a role in modulating the WNP anticyclonic anomalies. Therefore, the record-breaking rainfall extremes in East Asia that occurred during summer 2020 can be explained by the teleconnections associated with the tropical origins among the Indian, Pacific, and Atlantic Oceans and their interbasin interactions.


Assuntos
Clima , Oceano Atlântico , Extremo Oriente , Oceano Índico , Estações do Ano
17.
Sci Rep ; 12(1): 5254, 2022 03 28.
Artigo em Inglês | MEDLINE | ID: mdl-35347200

RESUMO

The Late Triassic saw a flourish of plant-arthropod interactions. By the Late Triassic, insects had developed all distinct strategies of herbivory, notably including some of the earliest occurrences of leaf-mining. Herein we describe exceptionally well-preserved leaf-mine trace fossils on a Cladophlebis Brongniart fern pinnule from the Momonoki Formation, Mine Group, Japan (Middle Carnian), representing the oldest unequivocal leaf-mines from East Asia. The mines all display a distinctive frass trail-a continuous meandering line, which later becomes a broad band containing spheroidal particles-demonstrating larval development. Although the shapes of the frass trails are generally comparable to those of Lepidoptera or Coleoptera, they cannot be unequivocally assigned to a specific extant leaf-mining taxon. Furthermore, elemental analyses by X-ray fluorescence (XRF) reveals that the frass trail comprises phosphate coprolites. The quantitative variations in P, S, and Si between coprolites and leaf veins may reflect physiological processes (e.g., consumption, absorption, and excretion) mediated by plant chemicals. Our findings reinforce the idea that leaf-mining had become a pervasive feeding strategy of herbivorous insects by the Late Triassic.


Assuntos
Fósseis , Herbivoria , Animais , Extremo Oriente , Herbivoria/fisiologia , Insetos/fisiologia , Plantas
18.
Reprod Health ; 19(1): 70, 2022 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-35305676

RESUMO

BACKGROUND: Gynaecological cancers are among the most prevalent cancers worldwide, with profound effects on the lives of women and their families. In this critical review, we explore the impacts of these cancers on quality of life (QOL) of women in Asian countries, and highlight areas for future inquiry. METHODS: A systematic search of the literature was conducted in six electronic databases: Web of Science, Scopus, Global Health (CAB Direct), PsycINFO (Ovid), EBMR (Ovid), and Medline (Ovid). Screening resulted in the inclusion of 53 relevant articles reporting on 48 studies. RESULTS: Most studies were conducted in high and upper-middle income countries in East Asia and used quantitative approaches. Women had predominantly been diagnosed with cervical or ovarian cancer, and most had completed treatment. Four key interrelated domains emerged as most relevant in shaping QOL of women affected by gynaecological cancer: support, including identified needs, sources and forms; mental health, covering psychological distress associated with cancer, risk and protective factors, and coping strategies; sexual function and sexuality, focused on physiological, emotional and relational changes caused by gynaecological cancers and treatments, and the impacts of these on women's identities; and physical health, covering the physical conditions associated with gynaecological cancers and their impacts on women's daily activities. CONCLUSION: QOL of women affected by gynaecological cancer is shaped by their mental and physical health, support, and changes in sexual function and sexuality. The limited number of studies from lower- and middle-income countries in South and Southeast Asia highlights important knowledge gaps requiring future research.


Multiple factors shape the quality of life of women affected by gynaecological cancers in Asian countries as elsewhere. We identified 53 articles reporting on 48 studies, most conducted in high- and upper-middle income East Asian countries, with much less attention to women in lower income countries in South and Southeast Asia. Most studies used quantitative research methods to gain an understanding of the impact on women diagnosed with cervical or ovarian cancer who had completed treatment. Women's quality of life was shaped by their mental and physical health, their support needs, and the changes they experienced in sexual function and sexuality.


Assuntos
Neoplasias dos Genitais Femininos , Qualidade de Vida , Adaptação Psicológica , Extremo Oriente , Feminino , Neoplasias dos Genitais Femininos/epidemiologia , Neoplasias dos Genitais Femininos/psicologia , Humanos , Qualidade de Vida/psicologia , Sexualidade
19.
PLoS One ; 17(3): e0263237, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35358196

RESUMO

Under the background of "the Belt and Road" and "the economic corridor of China, Mongolia and Russia" initiatives, it is of great significance to study the temporal and spatial economic pattern in the Russian Federation. Based on the economic development difference index, regional economic grade index, global trend analysis tool and spatial autocorrelation model, this paper analyzes the temporal and spatial pattern evolution characteristics of Russian economic differences from 2002 to 2020. The results are as following. First, although the economic imbalance among various federal subjects has been decreasing, the economic polarization has been still severe between the prosperous developed regions and the stagnant backward regions during 2002-2020. Russia's economy shows a trend of changing from significant positive correlation in strong agglomeration space to positive correlation in weak agglomeration space, and then to random distribution. Second, there has been great differences of the economic development among various federal subjects. The economic grade of the Russian federal subjects presents a significant spatial differentiation pattern. The Russian Federation's economic resources are concentrated in the first-class federal subject (Moscow City), second-class federal subjects (Tumen Region, Moscow Region and Saint-Petersburg city) and a few third-class federal subjects (Yamalo-Nenetsky Autonomous Area, Khanty-Mansiysky Autonomous Area, Republic of Tatarstan, Krasnodar Territory, Sverdlovsk Region, etc). Third, the Russian Federation's economy presents "High Core, Low Periphery", "High West, Low East" and "High south, Low north" spatial differentiation pattern. The economic hot regions coincide with the high-class economic regions, which are mainly distributed in the contiguous areas of Ural Federal District and Volga Federal District, as well as the Moscow City, Moscow Region, Saint-Petersburg city, Krasnodar Territory and Rostov Region. The economic cold regions coincide with the low-class economic regions, which are mainly located in the Far East Federal District, the east of Siberian Federal District, the north of North West Federal District and the south of North-Caucasian Federal District. Finally, we suggest the recommendation for policy makers in Russia. And we propose the future research ideas.


Assuntos
Economia , China , Extremo Oriente , Humanos , Mongólia , Moscou , Federação Russa
20.
Mol Phylogenet Evol ; 169: 107427, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-35131422

RESUMO

Evolutionary and biogeographic processes determine species richness patterns of vascular plants between Eastern Asia (EA) and Eastern North America (ENA). However, the strikingly higher species richness of EA relative to ENA remains poorly understood from this perspective. Here, we studied the relative importance of biogeographical, evolutionary and ecological factors underlying differences in species richness between EA and ENA in Podophylloideae (Berberidaceae, Ranunculales; in total 10 spp. in EA vs. 2 spp. in ENA). Based on large-scale transcriptome data, our phylogenomic analyses strongly supported Podophylloideae and its two multi-species genera, i.e. Dysosma (EA) and Diphylleia (EA/ENA), as monophyletic groups. Sinopodophyllum hexandrum (EA) was identified as sister to the remainder of Podophylloideae. Dysosma (7 spp.) was recovered as sister to Podophyllum peltatum (ENA), forming an EA-ENA disjunct pair with a strong bias of species diversity in the EA counterpart. Our biogeographic analyses support the 'out-of-Tibet' hypothesis, suggesting that Podophylloideae started to diversify in the Himalaya-Hengduan Mountains (Mid-Miocene) and migrated eastward (since the Late Miocene) into Central-eastern China, Japan, and ENA (only P. peltatum and Diphylleia cymosa). Overall, we conclude that the striking species diversity anomaly between EA and ENA in Podophylloideae may be explained by a combination of (1) a longer period of time available to accumulate species in EA; and (2) a greater diversification rate in EA, which might have been promoted by greater physiographic and environmental heterogeneity in this region.


Assuntos
Berberidaceae , Evolução Molecular , Filogenia , Ranunculales , Berberidaceae/genética , Extremo Oriente , América do Norte , Ranunculales/genética
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