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1.
Psychol Aging ; 36(6): 710-717, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34516174

RESUMO

Physical fatigability, or susceptibility to physical fatigue, is strongly associated with aging, disease, and disability. Over the lifecourse, personality traits are also connected to numerous age-related vulnerabilities and resistance-yet, their longitudinal association with fatigability remains unknown. Well-functioning community-dwelling volunteers aged ≥50 (N = 995) from the Baltimore Longitudinal Study of Aging (BLSA) were assessed over an average of 2 years on personality traits (NEO-PI-R; openness, conscientiousness, extraversion, agreeableness, and neuroticism) and perceived fatigability [Borg Rating of Perceived Exertion (RPE) after a 5-min slow treadmill walk; 6 (low) to 20 (high) exertion]. Linear and multinomial logistic regression models examined cross-sectional associations [treating fatigability continuously and by RPE category: low (6-7), intermediate (8-9), and high (10+)]. Generalized estimating equations (GEE) tested longitudinal associations. All models were adjusted for demographics and comorbid conditions. In cross-sectional models, openness, ß = -.09 RPE (SE =.03); p < .01, conscientiousness, ß = -.07 (.03); p < .05, and extraversion, ß = -.10 (.03); p < .01, were negatively associated with fatigability. In parallel, lower openness, OR: .98, 95% CI [.96-1.00], conscientiousness, OR: .98, 95% CI [.96-1.00], and extraversion, OR: .97, 95% CI [.95-.99], corresponded with higher odds of having high versus low fatigability. In longitudinal models (mean follow-up time 2 ± 2 years), openness, conscientiousness, and extraversion associations remained significant and did not change over time (Trait × Year p values > .34). Together, findings suggest that personality plays a role in the perceived tolerance of fatigue in well-functioning older adults. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Assuntos
Envelhecimento/psicologia , Fadiga/psicologia , Vida Independente/psicologia , Personalidade , Idoso , Baltimore , Estudos Transversais , Feminino , Humanos , Estudos Longitudinais , Masculino
2.
Health Qual Life Outcomes ; 19(1): 179, 2021 Jul 12.
Artigo em Inglês | MEDLINE | ID: mdl-34247645

RESUMO

BACKGROUND: Fatigability has recently emerged in oncology as a concept that anchors patients' perceptions of fatigue to defined activities of specified duration and intensity. This study aimed to examine the psychometric properties of the Korean version of the Pittsburgh Fatigability Scale (K-PFS) for women with breast cancer. METHODS: This cross-sectional study involved 196 women with breast cancer recruited from a tertiary hospital in Seoul, Korea. Reliability was evaluated using Cronbach's alpha, and confirmatory factor analysis was conducted to examine the factor structure of the K-PFS. Four goodness-of-fit values were evaluated: (1) the comparative fit index (CFI), (2) the Tucker-Lewis index (TLI), (3) the root mean square error of approximation (RMSEA), and (4) the standardized root mean square residual (SRMR). RESULTS: Of the 196 survivors, 71.1% had greater physical fatigability (K-PFS Physical score ≥ 15) and 52.6% had greater mental fatigability (K-PFS Mental score ≥ 13). The Cronbach's alpha coefficient for the total K-PFS scale was 0.926, and the coefficients for the physical and mental fatigability domains were 0.870 and 0.864, respectively. In the confirmatory factor analysis for physical fatigability, the SRMR value (0.076) supported goodness of fit, but other model fit statistics did not (CFI = 0.888, TLI = 0.826, and RMSEA = 0.224). For mental fatigability, although three goodness-of-fit values were acceptable (CFI = 0.948, TLI = 0.919, and SRMR = 0.057), the RMSEA value (0.149) did not indicate good model fit. However, each item coefficient was statistically significant (> 0.5), and the K-PFS was therefore found to be valid from a theoretical perspective. CONCLUSION: This study provides meaningful information on the reliability and validity of the K-PFS instrument, which was developed to meet an important need in the context of breast cancer survivors. Additional research should examine its test-retest reliability and construct validity with performance measures.


Assuntos
Neoplasias da Mama/psicologia , Sobreviventes de Câncer/psicologia , Fadiga/psicologia , Qualidade de Vida , Inquéritos e Questionários/normas , Adulto , Neoplasias da Mama/complicações , Estudos Transversais , Análise Fatorial , Fadiga/complicações , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Psicometria/instrumentação , Reprodutibilidade dos Testes , República da Coreia
4.
Commun Biol ; 4(1): 634, 2021 06 10.
Artigo em Inglês | MEDLINE | ID: mdl-34112935

RESUMO

Fatigue is a pervasive public health and safety issue. Common fatigue countermeasures include caffeine or other chemical stimulants. These can be effective in limited circumstances but other non-pharmacological fatigue countermeasures such as non-invasive electrical neuromodulation have shown promise. It is reasonable to suspect that other types of non-invasive neuromodulation may be similarly effective or perhaps even superior. The objective of this research was to evaluate the efficacy of cervical transcutaneous vagal nerve stimulation (ctVNS) to mitigate the negative effects of fatigue on cognition and mood. Two groups (active or sham stimulation) of twenty participants in each group completed 34 h of sustained wakefulness. The ctVNS group performed significantly better on arousal, multi-tasking, and reported significantly lower fatigue ratings compared to sham for the duration of the study. CtVNS could be a powerful fatigue countermeasure tool that is easy to administer, long-lasting, and has fewer side-effects compared to common pharmacological interventions.


Assuntos
Privação do Sono/psicologia , Privação do Sono/terapia , Estimulação do Nervo Vago/métodos , Adulto , Afeto/fisiologia , Cognição/fisiologia , Fadiga/patologia , Fadiga/psicologia , Fadiga/terapia , Feminino , Humanos , Masculino , Privação do Sono/patologia , Estresse Fisiológico/fisiologia , Estimulação Elétrica Nervosa Transcutânea/métodos , Nervo Vago/metabolismo , Nervo Vago/fisiologia , Vigília/efeitos dos fármacos
5.
Am J Clin Dermatol ; 22(4): 541-554, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33954933

RESUMO

BACKGROUND: Atopic dermatitis imparts a substantial patient burden, including itch, sleep disturbance, and decreased health-related quality of life. OBJECTIVE: This analysis evaluated changes in patient-reported outcomes of disease-specific signs/symptoms and health-related quality of life in adult and adolescent patients with moderate-to-severe atopic dermatitis treated with once-daily oral abrocitinib 200-mg or 100-mg monotherapy. METHODS: Pooled data from one phase IIb (NCT02780167) and two phase III (NCT03349060, JADE MONO-1; NCT03575871, JADE MONO-2) monotherapy trials in adult and adolescent patients with moderate-to-severe atopic dermatitis were analyzed. Patient-reported outcome assessments included: global severity, itch, and multi-item measures that assess other signs and symptoms of atopic dermatitis. Additional patient-reported outcome assessments measured depression, anxiety, fatigue, disease-specific and general health-related quality of life, and work and general productivity among employed patients. RESULTS: Overall, 942 patients were included in this analysis. Improvements were observed from the first post-baseline assessment to week 12 across all patient-reported outcomes, including Patient Global Assessment (PtGA) score of 0/1 (35.5%, 19.8%, and 5.9% for 200 mg, 100 mg, and placebo, respectively), ≥ 4-point improvement in Night Time Itch Scale (NTIS; 57.0%, 42.7%, and 12.7%), change from baseline in Patient-Oriented Eczema Measure (POEM) score (- 11.4, - 8.2, and - 3.4), 1-point improvement in Pruritus and Symptoms Assessment for Atopic Dermatitis (PSAAD; 75.2%, 65.1%, and 33.5%), Hospital Anxiety and Depression Scales (HADS) anxiety (- 2.0, - 1.7, and - 1.0) and depression (- 1.7, - 1.3, and - 0.1). CONCLUSIONS: Abrocitinib monotherapy improved disease-specific signs/symptoms and health-related quality of life across multiple domains as reported by adult and adolescent patients with moderate-to-severe atopic dermatitis, complementing clinician-reported efficacy and safety outcomes. CLINICAL TRIAL REGISTRATION: NCT02780167 (registered 23 May, 2016), NCT03349060 (registered 21 November, 2017), NCT03575871 (registered 3 July, 2018).


Assuntos
Dermatite Atópica/tratamento farmacológico , Inibidores de Janus Quinases/administração & dosagem , Prurido/tratamento farmacológico , Pirimidinas/administração & dosagem , Qualidade de Vida , Sulfonamidas/administração & dosagem , Administração Oral , Adolescente , Adulto , Idoso , Ansiedade/diagnóstico , Ansiedade/psicologia , Depressão/diagnóstico , Depressão/psicologia , Dermatite Atópica/complicações , Dermatite Atópica/diagnóstico , Dermatite Atópica/psicologia , Eficiência , Fadiga/diagnóstico , Fadiga/psicologia , Feminino , Humanos , Inibidores de Janus Quinases/efeitos adversos , Masculino , Pessoa de Meia-Idade , Medidas de Resultados Relatados pelo Paciente , Prurido/complicações , Prurido/diagnóstico , Prurido/psicologia , Pirimidinas/efeitos adversos , Índice de Gravidade de Doença , Sulfonamidas/efeitos adversos , Resultado do Tratamento , Adulto Jovem
6.
Nurs Res ; 70(4): 256-265, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33935213

RESUMO

BACKGROUND: Fatigue is a common symptom in adults with inflammatory bowel disease (IBD) and is influenced by many physiological, psychological, and situational factors. However, the influencing factors of fatigue associated with IBD have not been evaluated. OBJECTIVE: This study aims to examine factors associated with fatigue during IBD and develop a parsimonious model that describes the influencing factors of fatigue. METHODS: The study was a secondary analysis of cross-sectional data obtained from IBD Partners, an online cohort of adults with the disease, including 12,053 eligible participants. Data were collected using the Patient-Reported Outcomes Measurement Information System short-form scales measuring fatigue, sleep disturbances, pain interference, anxiety, depression, and satisfaction with social roles. Physical activity was measured using a single question. Demographic and clinical variables were collected. Path analysis was computed to identify the direct and indirect effects of situational, physiological, and psychological factors on IBD-fatigue based on the middle range theory of unpleasant symptoms' conceptual framework. RESULTS: Most of the participants were White females. The data best fit a model with situational factors (physical activity and satisfaction with social roles as the mediators). The direct effect of IBD activity, age, sleep disturbances, pain interference, anxiety, and depression on IBD-fatigue was significant. Significant indirect effects were noted on IBD-fatigue from sleep disturbances, pain interference, and depression via physical activity and satisfaction with social roles. DISCUSSION: The study identified two important intervening variables from the tested model. In addition, other symptoms such as sleep, pain, anxiety, and depression are essential and also influence IBD-fatigue.


Assuntos
Ansiedade/psicologia , Depressão/psicologia , Fadiga/psicologia , Doenças Inflamatórias Intestinais/complicações , Medidas de Resultados Relatados pelo Paciente , Adulto , Estudos Transversais , Feminino , Humanos , Masculino , Dor/psicologia , Sono/fisiologia , Interação Social , Inquéritos e Questionários
7.
Nurs Clin North Am ; 56(2): 175-187, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-34023114

RESUMO

Sleep-wake disturbances are common in patients with cancer. Despite the high prevalence of altered sleep patterns in oncology settings, there remains a gap in consistent assessment of sleep, leading to an underrecognized and undertreated condition. Provider failure in addressing sleep-wake disturbances can result in chronic issues with insomnia and has a negative impact on quality of life and cancer survivorship. Often sleep-wake disturbances present in symptom "clusters" including, anxiety, depression, and fatigue, which adds to the complexity of managing sleep disorders in oncology. Aggressive management strategies for managing underlying symptom burden from disease or medications effects is a priority.


Assuntos
Transtornos do Sono-Vigília/enfermagem , Fadiga/etiologia , Fadiga/psicologia , Humanos , Neoplasias/complicações , Neoplasias/psicologia , Enfermagem Oncológica/métodos , Enfermagem Oncológica/tendências , Cuidados Paliativos/métodos , Cuidados Paliativos/psicologia , Cuidados Paliativos/normas , Prevalência
8.
Nurs Clin North Am ; 56(2): 275-286, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-34023121

RESUMO

Sleep disturbances are common after traumatic brain injury of all levels of severity, interfere with acute and long-term recovery, and can persist for years after injury. There is increasing evidence of the importance of sleep in improving brain function and recovery. Noticing and addressing sleep disturbances are important aspects of nursing care, especially for the prevention or early recognition of delirium. Nonpharmacologic interventions can improve sleep. Teaching about the importance of sleep after traumatic brain injury, promoting sleep hygiene, and multidisciplinary approaches to addressing sleep problems and improving sleep are important for recovery from traumatic brain injury.


Assuntos
Lesões Encefálicas Traumáticas/complicações , Transtornos do Sono-Vigília/etiologia , Lesões Encefálicas Traumáticas/fisiopatologia , Lesões Encefálicas Traumáticas/psicologia , Distúrbios do Sono por Sonolência Excessiva/etiologia , Distúrbios do Sono por Sonolência Excessiva/psicologia , Fadiga/etiologia , Fadiga/psicologia , Humanos , Transtornos do Sono-Vigília/fisiopatologia , Transtornos do Sono-Vigília/psicologia
9.
NeuroRehabilitation ; 48(4): 469-480, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33998551

RESUMO

BACKGROUND: Coronavirus disease 2019 (COVID-19) patients present long-lasting physical and neuropsychological impairment, which may require rehabilitation. OBJECTIVES: The current cross-sectional study characterizes post COVID-19 sequelae and persistent symptoms in patients in an outpatient rehabilitation program. METHODS: Thirty patients [16 post-ICU and 14 non-ICU; median age = 54(43.8-62) years; 19 men] presenting sequelae and/or persistent symptoms (>3 months after acute COVID-19) were selected of 41 patients referred for neurorehabilitation. Patients underwent physical, neuropsychological and respiratory evaluation and assessment of impact of fatigue and quality of life. RESULTS: The main reasons for referral to rehabilitation were: fatigue (86.6%), dyspnea (66.7%), subjective cognitive impairment (46.7%) and neurological sequelae (33.3%). Post-ICU patient presented sequelae of critical illness myopathy and polyneuropathy, stroke and encephalopathy and lower forced vital capacity compared to non-ICU patients. Cognitive impairment was found in 63.3% of patients, with a similar profile in both sub-groups. Increased physical fatigue, anxiety and depression and low quality of life were prevalent irrespective of acute COVID-19 severity. CONCLUSIONS: The variability of post COVID-19 physical and neuropsychological impairment requires a complex screening process both in ICU and non-ICU patients. The high impact of persistent symptoms on daily life activities and quality of life, regardless of acute infection severity, indicate need for rehabilitation.


Assuntos
Assistência Ambulatorial/métodos , COVID-19/reabilitação , Disfunção Cognitiva/reabilitação , Fadiga/reabilitação , Ambulatório Hospitalar , Adulto , COVID-19/complicações , COVID-19/psicologia , Disfunção Cognitiva/etiologia , Disfunção Cognitiva/psicologia , Estudos Transversais , Fadiga/etiologia , Fadiga/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Testes Neuropsicológicos , Qualidade de Vida/psicologia , SARS-CoV-2
10.
Paediatr Drugs ; 23(4): 317-329, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33997945

RESUMO

Pediatric-onset multiple sclerosis (POMS), representing approximately 5% of all MS cases, affects the central nervous system during its ongoing development. POMS is most commonly diagnosed during adolescence but can occur in younger children as well. For pediatric patients with MS, it is critical to manage the full impact of the disease and monitor for any effects on school and social functioning. Disease management includes not only disease-modifying therapies but also strategies to optimize wellbeing. We review the interventions with the highest evidence of ability to improve the disease course and quality of life in POMS. High levels of vitamin D and a diet low in saturated fat are associated with lower relapse rates. Exercise ameliorates fatigue and sleep. Behavioral strategies for sleep hygiene and mood regulation can also improve fatigue and perceived health. POMS management should be addressed holistically, including assessing overall symptom burden as well as the psychological and functional impact of the disease.


Assuntos
Afeto/fisiologia , Cognição/fisiologia , Esclerose Múltipla/psicologia , Esclerose Múltipla/terapia , Qualidade de Vida/psicologia , Adolescente , Antioxidantes/administração & dosagem , Criança , Gerenciamento Clínico , Exercício Físico/fisiologia , Exercício Físico/psicologia , Fadiga/etiologia , Fadiga/psicologia , Fadiga/terapia , Humanos , Estudos Longitudinais , Maconha Medicinal/administração & dosagem , Esclerose Múltipla/complicações , Vitamina D/administração & dosagem
12.
Holist Nurs Pract ; 35(3): 150-157, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33853099

RESUMO

This randomized controlled clinical trial was conducted to determine the effect of music therapy on fatigue, comfort and vital signs of the liver transplant patients. The study sample comprised 120 adult patients (60 in the experimental and 60 in the control group) who met the inclusion criteria and agreed to participate in the study. In the experimental group, the researcher performed music therapy. After applying music therapy once to patients for 30 minutes, their fatigue, comfort, and vital signs were evaluated. No treatment was performed in the control group. According to music therapy follow-ups after liver transplantation, mean scores of fatigue levels were lower, comfort levels were higher, and vital signs were normal, with a statistical significance in the experimental group compared with the control group in all measurements before and after music therapy (P < .001). The study should be repeated using different parameters.


Assuntos
Fadiga/terapia , Musicoterapia/normas , Conforto do Paciente/normas , Adulto , Fadiga/psicologia , Feminino , Humanos , Transplante de Fígado/métodos , Transplante de Fígado/psicologia , Masculino , Pessoa de Meia-Idade , Musicoterapia/métodos , Conforto do Paciente/estatística & dados numéricos , Complicações Pós-Operatórias/prevenção & controle , Complicações Pós-Operatórias/psicologia , Sinais Vitais/fisiologia
13.
Traffic Inj Prev ; 22(5): 378-383, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33881365

RESUMO

OBJECTIVE: Vehicle automation shifts the driver's role from active operator to passive observer at the potential cost of degrading their alertness. This study investigated the role of an in-vehicle voice-based assistant (VA; conversing about traffic/road environment) to counter the disengaging and fatiguing effects of automation. METHOD: Twenty-four participants undertook two drives- with and without VA in a partially automated vehicle. Participants were subsequently categorized into high and low participation groups (based on their proportion of vocal exchanges with VA). The effectiveness of VA was assessed based on driver alertness measured using Karolinska Sleepiness Scale (KSS), eye-based sleepiness indicators and glance behavior, NASA-TLX workload rating and time to gain motor readiness in response to take-over request and performance rating made by the drivers. RESULTS: Paired samples t-tests comparison of alertness measures across the two drives were conducted. Lower KSS rating, larger pupil diameter, higher glances (rear-mirror, roadside vehicles and signals in the drive with VA) and higher feedback ratings of VA indicated the efficiency of VA in improving driver alertness during automation. However, there was no significant difference in alertness or glance behavior between the driver groups (high and low-PR), although the time to resume steering control was significantly lower in the higher engagement group. CONCLUSION: The study successfully demonstrated the advantages of using a voice assistant (VA) to counter these effects of passive fatigue, for example, by reducing the time to gain motor-readiness following a TOR. The findings show that despite the low engagement in spoken conversation, active listening also positively influenced driver alertness and awareness during the drive in an automated vehicle.


Assuntos
Acidentes de Trânsito/psicologia , Atenção/fisiologia , Automação , Condução de Veículo/psicologia , Sonolência , Análise e Desempenho de Tarefas , Adulto , Estudos de Casos e Controles , Simulação por Computador , Fadiga/psicologia , Humanos , Masculino , Vigília
14.
Health Qual Life Outcomes ; 19(1): 135, 2021 Apr 29.
Artigo em Inglês | MEDLINE | ID: mdl-33926461

RESUMO

BACKGROUND: Fatigue negatively influences health-related quality of life. It is questionable whether fatigue is sufficiently covered by the EQ-5D. This study investigated whether fatigue is covered by the existing domains of the EQ-5D. METHODS: A Dutch general population sample completed the EQ-5D (3L and 5L version) and the Rivermead Post-Concussion Symptoms Questionnaire (RPQ), of which the fatigue item was used. Outcomes were compared between participants with and without a chronic health condition. Convergent validity was assessed, and multivariate regression analyses was used to predict the RPQ fatigue item from the EQ-5D-3L and EQ-5D-5L domains separately. RESULTS: 3027 people completed the survey, of whom 52% had ≥ 1 chronic health condition. Fatigue was reported by 48% of the participants. Fatigue was moderately correlated to the EQ-5D domains 'pain/discomfort', 'usual activities', and 'anxiety/depression' for the 3L (r = 0.379-0.426) and 5L version (r = 0.411-0.469). For the 5L, also a moderate correlation with 'mobility' (r = 0.335) was observed. The remaining correlations were weak. All EQ-5D-3L and 5L domains except for 'mobility' were significantly associated with the RPQ fatigue item (unstandardized Beta = - 0.20-0.67; p < 0.01 to p = 0.04). Comparable outcomes were found for participants with and without ≥ 1 chronic health condition. CONCLUSIONS: The extent to which fatigue is covered by the EQ-5D domains is small to moderate, with the EQ-5D-5L being slightly more sensitive to capture fatigue compared to the EQ-5D-3L. An extra fatigue item for the EQ-5D may add value, as fatigue is not fully captured by the existing domains, both in people with and without a chronic health condition.


Assuntos
Fadiga/psicologia , Qualidade de Vida , Inquéritos e Questionários/normas , Adulto , Doença Crônica/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Países Baixos , Reprodutibilidade dos Testes , Adulto Jovem
15.
J Appl Psychol ; 106(3): 330-344, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33871270

RESUMO

In response to the Coronavirus disease 2019 (COVID-19) global health pandemic, many employees transitioned to remote work, which included remote meetings. With this sudden shift, workers and the media began discussing videoconference fatigue, a potentially new phenomenon of feeling tired and exhausted attributed to a videoconference. In the present study, we examine the nature of videoconference fatigue, when this phenomenon occurs, and what videoconference characteristics are associated with fatigue using a mixed-methods approach. Thematic analysis of qualitative responses indicates that videoconference fatigue exists, often in near temporal proximity to the videoconference, and is affected by various videoconference characteristics. Quantitative data were collected each hour during five workdays from 55 employees who were working remotely because of the COVID-19 pandemic. Latent growth modeling results suggest that videoconferences at different times of the day are related to deviations in employee fatigue beyond what is expected based on typical fatigue trajectories. Results from multilevel modeling of 279 videoconference meetings indicate that turning off the microphone and having higher feelings of group belongingness are related to lower postvideoconference fatigue. Additional analyses suggest that higher levels of group belongingness are the most consistent protective factor against videoconference fatigue. Such findings have immediate practical implications for workers and organizations as they continue to navigate the still relatively new terrain of remote work. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Assuntos
COVID-19/prevenção & controle , COVID-19/psicologia , Fadiga/etiologia , Identificação Social , Isolamento Social , Teletrabalho , Comunicação por Videoconferência , Adolescente , Adulto , Fadiga/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Saúde do Trabalhador , Fatores de Proteção , Pesquisa Qualitativa , Análise de Regressão , Fatores de Risco , Adulto Jovem
16.
Anesth Analg ; 132(5): 1338-1343, 2021 05 01.
Artigo em Inglês | MEDLINE | ID: mdl-33857976

RESUMO

The negative impacts of sleep deprivation and fatigue have long been recognized. Numerous studies have documented the ill effects of impaired alertness associated with the disruption of the sleep-wake cycle; these include an increased incidence of human error-related accidents, increased morbidity and mortality, and an overall decrement in social, financial, and human productivity. While there are multiple studies on the impact of sleep deprivation and fatigue in resident physicians, far fewer have examined the effects on attending physicians, and only a handful addresses the accumulated effects of chronic sleep disturbances on acute sleep loss during a night call-shift. Moreover, the rapid and unprecedented spread of coronavirus disease 2019 (COVID-19) pandemic significantly increased the level of anxiety and stress on the physical, psychological, and the economic well-being of the entire world, with heightened effect on frontline clinicians. Additional studies are necessary to evaluate the emotional and physical toll of the pandemic in clinicians, and its impact on sleep health, general well-being, and performance.


Assuntos
COVID-19/epidemiologia , COVID-19/psicologia , Competência Clínica/normas , Privação do Sono/epidemiologia , Privação do Sono/psicologia , Tolerância ao Trabalho Programado/psicologia , COVID-19/terapia , Fadiga/epidemiologia , Fadiga/psicologia , Humanos
17.
J Sports Sci Med ; 20(1): 1-8, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-33707980

RESUMO

Volleyball is a team sport with high physical and perceptual-cognitive demand, hence, increasing the perception of physical and mental fatigue during a competition. To alleviate fatigue (physical and mental), mindfulness and music have been proposed. The aim of this study was to analyze the effect of mindfulness-based mental versus music training on mental fatigue, physical fatigue, and recovery in elite competitive female volleyball athletes using a randomized two-controlled study with follow-up. Participants were 30 elite female Brazilian volleyball athletes. Athletes were randomly assigned to the following groups: 1) mindfulness-based mental training group (MBMT); 2) music-based training group (MBT); or 3) control group (CG). Three variables were evaluated as follows: 1) recovery based on total quality recovery; 2) mental fatigue visual analog scale; and 3) physical fatigue visual analog scale. Regarding recovery, there was no difference between the MBMT, MBT, and CG groups (p > 0.05). A difference in mental fatigue was noted between MBT and CG at follow-up [F(2,26) = 5.71, p = 0.009; large]. Regarding physical fatigue, there was no difference between the MBMT, MBT, and CG groups (p > 0.05). The mindfulness intervention effectively attenuated the mental fatigue caused by competition in volleyball athletes. These results will assist coaches and staff in providing fatigue management and reinforce the applicability of mental training in sports.


Assuntos
Atletas , Fadiga/terapia , Atenção Plena/educação , Musicoterapia , Voleibol/fisiologia , Adolescente , Atletas/psicologia , Fadiga/diagnóstico , Fadiga/psicologia , Feminino , Seguimentos , Humanos , Fadiga Mental/diagnóstico , Fadiga Mental/psicologia , Fadiga Mental/terapia , Recuperação de Função Fisiológica , Sensação , Esportes de Equipe , Escala Visual Analógica , Voleibol/psicologia
19.
Breast ; 56: 103-109, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33668004

RESUMO

BACKGROUND: Low-grade inflammation has been associated with cancer related fatigue (CRF). However, most studies focused on CRF during or shortly after treatment. Longitudinal studies are rare with inconsistent results. We assessed the association of inflammatory biomarkers with total CRF and all subdomains (physical, cognitive, affective) in long-term breast cancer survivors. METHOD: Patients recruited between 2002 and 2005 provided information on CRF at first follow-up (FU1) (N = 1292) and second follow-up (FU2) (N = 1205), after a median of 6.2 years and 11.7 years, respectively. Associations of 11 inflammatory biomarkers with CRF at FU1 and at FU2 were assessed using linear regression models. Logistic regression models were used to compare patients fatigued at both time-points and those never fatigued (N = 932). RESULTS: C-reactive protein (CRP) was significantly associated with total CRF at FU1 (ß = 1.47, 95%CI = 0.62-2.31, p = 0.0007), at FU2 (ß = 1.98, 95 %CI = 0.96-2.99, p = 0.0001) and with persistent CRF (OR = 1.29, 95%CI = 1.13-1.47, p < 0.0001). IL-6 levels were associated with total CRF at FU1 (ß = 1.01, 95%CI = 0.43-1.59, p = 0.0006), but not with CRF at FU2 or persistent CRF. No association remained significant after adjustment for relevant covariates. DISCUSSION: CRP and Il-6 were associated with risk of CRF in long-term breast cancer survivors, but were not independent of other known risk factors, suggesting that currently studied inflammatory markers are not suitable to identify patients at risk of long-term CRF.


Assuntos
Neoplasias da Mama/psicologia , Sobreviventes de Câncer/psicologia , Fadiga/etiologia , Qualidade de Vida , Idoso , Biomarcadores Tumorais , Neoplasias da Mama/complicações , Proteína C-Reativa/análise , Citocinas/sangue , Fadiga/sangue , Fadiga/psicologia , Feminino , Humanos , Inflamação , Interleucina-6/sangue , Pessoa de Meia-Idade
20.
Cancer Med ; 10(8): 2531-2565, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-33749151

RESUMO

Breast cancer patients often experience symptoms that adversely affect their quality of life. It is understood that many of these symptoms tend to cluster together: while they might have different manifestations and occur during different phases of the disease trajectory, the symptoms often have a common aetiology that is a potential target for intervention. Understanding the symptom clusters associated with breast cancer might usefully inform the development of effective care plans for affected patients. The aim of this paper is to provide an updated systematic review of the known symptom clusters among breast cancer patients during and/or after cancer treatment. A search was conducted using five databases for studies reporting symptom clusters among breast cancer patients. The search yielded 32 studies for inclusion. The findings suggest that fatigue-sleep disturbance and psychological symptom cluster (including anxiety, depression, nervousness, irritability, sadness, worry) are the most commonly-reported symptom clusters among breast cancer patients. Further, the composition of symptom clusters tends to change across various stages of cancer treatment. While this review identified some commonalities, the different methodologies used to identify symptom clusters resulted in inconsistencies in symptom cluster identification. It would be useful if future studies could separately examine the symptom clusters that occur in breast cancer patients undergoing a particular treatment type, and use standardised instruments across studies to assess symptoms. The review concludes that further studies could usefully determine the biological pathways associated with various symptom clusters, which would inform the development of effective and efficient symptom management strategies.


Assuntos
Neoplasias da Mama/complicações , Depressão/psicologia , Fadiga/psicologia , Transtornos do Sono-Vigília/psicologia , Neoplasias da Mama/psicologia , Neoplasias da Mama/terapia , Depressão/etiologia , Fadiga/etiologia , Feminino , Humanos , Psicometria , Transtornos do Sono-Vigília/etiologia , Avaliação de Sintomas
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