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1.
J Am Board Fam Med ; 34(Suppl): S21-S25, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-33622812

RESUMO

Pharmacists' roles and training have evolved to prepare pharmacists to provide clinical patient care services as part of interdisciplinary teams in primary care settings. Especially now, amidst a global health crisis such as COVID-19, patients may become more aware of their health status and be exposed to increased medical information in the media. Additionally, some patients may have delayed routine care, which may result in exacerbations of chronic disease states. Pharmacists can help alleviate the burden on primary care providers by serving as a drug information resource for patients and staff while providing patient education on management of chronic disease states.


Assuntos
Equipe de Assistência ao Paciente/organização & administração , Educação de Pacientes como Assunto/organização & administração , Farmacêuticos/organização & administração , Atenção Primária à Saúde/organização & administração , Papel Profissional , /diagnóstico , /terapia , Doença Crônica , Humanos , Pandemias , Educação de Pacientes como Assunto/métodos , Atenção Primária à Saúde/métodos , Estados Unidos/epidemiologia
2.
Artigo em Inglês | MEDLINE | ID: mdl-33445750

RESUMO

BACKGROUND: Immunization rates among the adult population in Poland are below desired targets, urging the need to expand this service in the community. During the COVID-19 pandemic, the ultimate goals for limiting the spread of the infection are vaccines against SARS-CoV-2. Pharmaceutical companies are in a race for the fastest possible way to deliver vaccines. Community pharmacists in Poland are recognised as an accessible yet underutilised group of medical professionals. Therefore, involving pharmacists in vaccinations may have beneficial results for the healthcare system. OBJECTIVES: The objectives of this study were to assess the readiness and willingness of community pharmacists following the Pharmacist Without Borders project who had either been trained or not in providing immunization services, and to identify the factors that may support the implementation of such services in Poland. METHODS: This study was conducted among pharmacists between February and August 2020 in Poland. A survey was developed to determine their readiness to provide vaccination services in their pharmacies, to recognise any barriers to vaccinations, as well as the factors necessary to implement vaccination services in Polish pharmacies. RESULTS: A total of 1777 pharmacists participated in the study, comprising 127 (7.1%) pharmacists trained in vaccinations during the Pharmacists Without Borders project and 1650 (92.9%) pharmacists not participating in the workshops. Pharmacists participating in the workshops more often indicated that providing vaccinations in community pharmacies would improve the overall vaccination rate (p = 0.0001), and that pharmacists could play an important role in advertising and promoting vaccinations (p = 0.0001). For the pharmacists not participating in the workshops, they indicated to a much greater extent possible barriers affecting the readiness to provide vaccinations in pharmacies. They most often pointed out that vaccination services would result in a significant workload increase (p = 0.0001), that pharmacies were not adapted to immunization, and that there were not enough training courses for pharmacists (p = 0.0001). CONCLUSION: The pharmacists working in community pharmacies indicated many advantages of vaccinations in pharmacies. This study identified barriers to the introduction of vaccinations and factors necessary to implement these services in pharmacies. The pharmacists trained during the immunization programme of the Pharmacists Without Borders project showed a greater readiness to provide immunization services.


Assuntos
Serviços Comunitários de Farmácia/organização & administração , Programas de Imunização/organização & administração , Farmacêuticos/organização & administração , Adulto , Humanos , Imunização , Pandemias , Farmacêuticos/psicologia , Polônia , Papel Profissional , Vacinação
3.
Am J Med ; 134(4): 456-461, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-33472055

RESUMO

Nonoptimized medication regimens cost patients and payors in the United States more than $528 billion in additional health care expenses each year. Comprehensive medication management is a patient-centered approach to medication optimization delivered by a clinical pharmacist working with the patient, physicians, and other members of the health care team. Comprehensive medication management ensures medications are assessed for appropriateness, effectiveness, and safety given the patient's clinical status, comorbidities, and other medications, as well as the patient's ability to take the medications as intended and adhere to the regimen. This article reviews the growing body of literature demonstrating the value of comprehensive medication management in achieving the quadruple aim of health care: better care, reduced health care costs, an improved patient experience, and provider well-being.


Assuntos
Prescrições de Medicamentos/economia , Prescrições de Medicamentos/normas , Conduta do Tratamento Medicamentoso , Preparações Farmacêuticas/administração & dosagem , Preparações Farmacêuticas/economia , Humanos , Farmacêuticos/organização & administração , Estados Unidos
4.
Res Social Adm Pharm ; 17(1): 1845-1852, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33317763

RESUMO

Pharmacies have been practicing innovative infection control measures during COVID-19. This article seeks to explore the current activities undertaken across various community pharmacy settings in relation to the safety of the workplace environment for staff and patients. METHODS: An online cross-sectional survey was conducted in Australia during the COVID-19 outbreak from 1st to 30th April 2020, addressing community pharmacist's awareness and response to infection and sanitation control. RESULTS: A total of 137 pharmacists took part in the survey. Regular cleaning took place in the pharmacy, but the use of gloves while cleaning was not regularly practice (48.18%). In addition, only 46.72% of respondents reported observing script baskets being cleaned and disinfected. About one-third (37.96%) of pharmacists were aware of the two-step cleaning and disinfecting process, with only 18.98% of pharmacist practicing such cleaning procedures. More than half of surveyed pharmacists reported having difficulty keeping up with pharmacy practice and infection control guidelines during the pandemic. CONCLUSION: This study demonstrates that the majority of pharmacists are not fully aware of the proper infection control measures needed in a community pharmacy setting. Pharmacists must play a bigger role in infection control measures to ensure staff and public health safety.


Assuntos
/prevenção & controle , Serviços Comunitários de Farmácia/organização & administração , Controle de Infecções/métodos , Farmacêuticos/organização & administração , Adolescente , Adulto , Idoso , Austrália , Estudos Transversais , Desinfecção/métodos , Feminino , Humanos , Controle de Infecções/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Farmacêuticos/estatística & dados numéricos , Papel Profissional , Inquéritos e Questionários , Adulto Jovem
5.
Res Social Adm Pharm ; 17(1): 1853-1858, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33317764

RESUMO

BACKGROUND: The practical experiences of active pharmacists involved in managing critically ill patients with coronavirus disease 2019 (COVID-19) have been rarely reported. OBJECTIVE: This work aimed to share professional experiences on medication optimization and provide a feasible reference for the pharmaceutical care of critically ill patients with COVID-19. METHODS: This study was conducted in a COVID-19-designated hospital in China. A group of dedicated clinical pharmacists participated in multidisciplinary rounds to optimize the treatments for critically ill patients with COVID-19. Consensus on medication recommendations was reached by a multidisciplinary team through bi-daily discussion. Related drug, classification, cause, and adjustment content for recommendations were recorded and reviewed. RESULTS: A total of 111 medication recommendations were supplied for 22 out of 33 (56.7%) critically ill patients from 1 February 2020 to 18 March 2020, and 106 (95.5%) of these were accepted. Among these recommendations, 64 (67.7%), 32 (28.8%), and 15 (13.5%) were related to antibiotics and antifungals, antiviral agents, and other drugs, respectively. Recommendation types significantly differed for different anti-infectives (p < 0.05). For antibiotics and antifungals, treatment effectiveness accounted for 60.9% of recommendation types, with 15 (38.5%) cases related to untreated infections. For antiviral agents, adverse drug events were the most common recommendation types (84.4%), with 20 (74.1%) cases related to liver function dysfunction. Discontinuation of suspected antiviral agents (66.7%) was usually recommended after the occurrence of adverse events that may progress and bring poor outcomes. CONCLUSION: Forceful and extensive on-ward participation is recommended for clinical pharmacists in managing critically ill patients. Our experiences highlight the need for special attention toward untreated infections and adverse events related to antiviral agents.


Assuntos
/terapia , Unidades de Terapia Intensiva , Farmacêuticos/organização & administração , Serviço de Farmácia Hospitalar/organização & administração , Adulto , Idoso , Idoso de 80 Anos ou mais , Antivirais/administração & dosagem , Antivirais/efeitos adversos , China , Estado Terminal , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Equipe de Assistência ao Paciente/organização & administração , Papel Profissional , Estudos Retrospectivos
6.
Res Social Adm Pharm ; 17(1): 1799-1806, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33317760

RESUMO

BACKGROUND: Since the start of the new Coronavirus (COVID-19) outbreak in December 2019, pharmacists worldwide are playing a key role adopting innovative strategies to minimize the adverse impact of the pandemic. OBJECTIVES: To identify and describe core services provided by the pharmacist during the COVID-19 pandemic. METHODS: A literature search was performed in MEDLINE, Embase, Scopus, and LILACS for studies published between December 1st, 2019 and May 20th, 2020 without language restriction. Studies that reported services provided by pharmacists during the COVID-19 pandemic were included. Two independent authors performed study selection and data extraction with a consensus process. The pharmacist's intervention identified in the included studies were described based on key domains in the DEPICT v.2. RESULTS: A total of 1189 records were identified, of which 11 studies fully met the eligibility criteria. Most of them were conducted in the United States of America (n = 4) and China (n = 4). The most common type of publication were letters (n = 4) describing the workplace of the pharmacist in hospitals (n = 8). These findings showed the different roles of pharmacists during the COVID-19 pandemic, such as disease prevention and infection control, adequate storage and drug supply, patient care and support for healthcare professionals. Pharmacists' interventions were mostly conducted for healthcare professionals and patients (n = 7), through one-to-one contact (n = 11), telephone (n = 6) or video conference (n = 5). The pharmacists' main responsibility was to provide drug information for healthcare professionals (n = 7) as well as patient counseling (n = 8). CONCLUSIONS: A reasonable number of studies that described the role of the pharmacists during the COVID-19 pandemic were found. All studies reported actions taken by pharmacists, although without providing a satisfactory description. Thus, future research with more detailed description as well as an evaluation of the impact of pharmacist intervention is needed in order to guide future actions in this and/or other pandemic.


Assuntos
/terapia , Assistência Farmacêutica/organização & administração , Farmacêuticos/organização & administração , /epidemiologia , Humanos , Papel Profissional
7.
Res Social Adm Pharm ; 17(1): 1925-1928, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33317766

RESUMO

The COVID-19 pandemic is putting enormous pressure on healthcare systems worldwide and various countries are struggling to flatten the curve to prevent their healthcare system from becoming overwhelmed. Studies have shown that people with chronic kidney disease (CKD) are at increased risk of COVID-19 infection and mortality. However, the interruption of routine care and support due to the current challenges with healthcare providers, facilities, and essential medicines due to this pandemic is adversely affecting people with CKD. This is because poor management of this disease leads to negative health outcomes. In order to maintain good health, this vulnerable group of patients rely heavily on the extended role of the community pharmacists in chronic disease management. This paper highlights the extended role of the community pharmacists in CKD management supportive care during the COVID-19 pandemic.


Assuntos
Serviços Comunitários de Farmácia/organização & administração , Farmacêuticos/organização & administração , Insuficiência Renal Crônica/terapia , Assistência à Saúde/organização & administração , Humanos , Papel Profissional , Insuficiência Renal Crônica/mortalidade
8.
Res Social Adm Pharm ; 17(1): 1929-1933, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33317767

RESUMO

The International Pharmaceutical Federation (FIP), as the global leadership body for pharmacists, pharmaceutical scientists and pharmaceutical educators, coordinated and produced as of January 2020 an international response to the COVID-19 pandemic. FIP's response included professional guidance, a programme of digital events and other resources, as well as advocacy and policy tools to support national pharmacists' associations and academic institutions, as well as individual practitioners, in their response at country level. This article describes the strategy adopted by FIP in collaboration with an international group of experts to support the valuable service that pharmacists and their teams provide to communities throughout the pandemic, and their important contribution to easing the huge strain being placed on health systems around the world.


Assuntos
/epidemiologia , Cooperação Internacional , Assistência Farmacêutica/organização & administração , Farmacêuticos/organização & administração , Assistência à Saúde/organização & administração , Humanos , Agências Internacionais , Internacionalidade , Papel Profissional
9.
Res Social Adm Pharm ; 17(1): 2002-2004, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33317768

RESUMO

BACKGROUND: Community pharmacists and their teams are easy accessible healthcare providers with an important role in primary care. As a consequence of the COVID-19 epidemic, (pharmaceutical) care and specifically communication between patients and healthcare providers is compromised. OBJECTIVE: To describe the impact of the COVID-19 epidemic on the provision of pharmaceutical care in the Netherlands. METHODS: A cross-sectional study with an online questionnaire was sent to community pharmacies in the Netherlands. The questionnaire covered the following main topics: changes in pharmacy setting and logistic procedures, communication about medication and baseline characteristics. RESULTS: Pharmacies implemented hygiene measures and minimized direct patient-provider contact, e.g. by delivering medication at home to a wider range of patients (47.0%), temporarily not conducting medication reviews (55.8%) and only performing inhalation instructions via telephone (22.3%). Only a small number of pharmacies used telepharmacy, such as video calling during patient education and counseling. A total of 76.7% of the participants expressed concerns towards the pharmaceutical care for vulnerable patients. CONCLUSIONS: Our results show considerable impact of the COVID-19 epidemic on both logistic procedures and services regarding patient education and counseling. Pharmacies should be stimulated to implement telepharmacy or remote service to optimally support patients during the COVID-19 epidemic.


Assuntos
/epidemiologia , Serviços Comunitários de Farmácia/organização & administração , Farmacêuticos/organização & administração , Adulto , Comunicação , Estudos Transversais , Feminino , Acesso aos Serviços de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Países Baixos , Educação de Pacientes como Assunto/métodos , Atenção Primária à Saúde/organização & administração , Papel Profissional , Inquéritos e Questionários , Telemedicina/organização & administração
10.
Front Public Health ; 8: 561924, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33364224

RESUMO

Severe acute respiratory syndrome caused by the novel coronavirus (SARS-CoV-2) was first reported in China in December 2019 which was later declared to be a public health emergency of international concern by the World Health Organization (WHO). This virus proved to be very contagious resulting in life-threatening respiratory intricacies posing overall public health and governance challenges. Amid the coronavirus pandemic and the unprecedented increase in healthcare demands, only inventive and adaptive practice among healthcare professionals is the need of the hour. Pharmacy services are an important mainstay in the public health and have considerable potential to combat the coronavirus disease 2019 (COVID-19) pandemic. Pharmacists working in several localities and health facilities are linked to patients either directly or indirectly. They can act swiftly in public health response such as drafting professional service guidance to pharmacists working in various healthcare facilities, ensuring effective medicine supply system, monitoring and resolving drug shortage issues, establishing and promoting remote pharmacy services, counseling the public on infection prevention basics, educating about proper use of personal protective equipment, discouraging self-medication, participating in clinical trials, small-scale manufacturing of sanitizers and disinfectants, busting the prevailing myths, and conducting drug evaluation and active surveillance. These interventions will help ease unprecedented burden on healthcare facilities during the ongoing pandemic and eventually will add value to patients and the healthcare system. The current manuscript accentuates the potential roles and activities that pharmacists can initiate in various healthcare facilities to help in relieving pressure on the overwhelmed healthcare system. The information and suggestions offered in this review could help in the restructuring of existing pharmacy services by governments, public health bodies, and policy makers in response to the COVID-19 pandemic. Moreover, this manuscript will underscore any unrealized potential among pharmacists working in various sectors including community, hospital, industry, and drug regulatory authorities.


Assuntos
/epidemiologia , Assistência à Saúde/organização & administração , Farmacêuticos/organização & administração , Papel Profissional , Saúde Pública , China , Humanos
11.
PLoS One ; 15(8): e0237338, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32797093

RESUMO

OBJECTIVE: The study was aimed to explore patient safety culture of community pharmacists working in Dessie and Gondar towns, Northern Ethiopia. METHODS: A cross-sectional study was conducted from 1st to 31st March 2018. In this cross-sectional survey, the Pharmacy Survey on Patient Safety Culture (PSOPSC), developed by the Agency for Healthcare Research and Quality (AHRQ), was used to collect data. PSOPSC is a self-administered questionnaire. The questionnaire was distributed among staffs who work in community pharmacies of Dessie and Gondar towns. All staffs available on data collection period in the pharmacy were included. The Statistical Package for Social Science (SPSS) software version 25 was used to enter and analyze the data. RESULTS: A total of 120 participants were approached and completed the questionnaire. Results from the study showed that high positive response rate was demonstrated in the domains of "Teamwork" (90.2%) followed by physical space and environment (83.1%). On the other hand, the result also identified that there is an enormous problem related to mistake communication (44.8%) and work pressure (45%). In addition, significant difference of percent positive responses were obtained across towns and staff working hours. CONCLUSIONS: The patient safety culture of community pharmacists is appreciable especially with respect to their teamwork. Besides, urgent attention should be given to areas of weakness, mainly in the domain of "mistake communication" and "staffing and work pressure".


Assuntos
Serviços Comunitários de Farmácia/organização & administração , Segurança do Paciente , Farmacêuticos/organização & administração , Gestão da Segurança/estatística & dados numéricos , Adulto , Serviços Comunitários de Farmácia/estatística & dados numéricos , Estudos Transversais , Etiópia , Feminino , Humanos , Relações Interprofissionais , Masculino , Pessoa de Meia-Idade , Admissão e Escalonamento de Pessoal/organização & administração , Admissão e Escalonamento de Pessoal/estatística & dados numéricos , Farmacêuticos/psicologia , Farmacêuticos/estatística & dados numéricos , Inquéritos e Questionários/estatística & dados numéricos , Carga de Trabalho/psicologia , Carga de Trabalho/estatística & dados numéricos , Adulto Jovem
12.
Prev Chronic Dis ; 17: E74, 2020 07 30.
Artigo em Inglês | MEDLINE | ID: mdl-32730199

RESUMO

Medically underserved patients in rural areas are more vulnerable to poor health outcomes, including the risks associated with coronavirus disease 2019 (COVID-19). Pharmacists, student pharmacists, and other health care professionals are working together to implement new, innovative ways to deliver the same standard of care during the COVID-19 pandemic to these vulnerable patients. These services include telehealth with virtual and telephone medication therapy management sessions led by ambulatory care pharmacists and student pharmacists. Pharmacists, student pharmacists, and other health care professionals should continue to adapt to these new technologies to improve health outcomes for their patients during the pandemic.


Assuntos
Betacoronavirus , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/prevenção & controle , Área Carente de Assistência Médica , Pandemias/prevenção & controle , Farmacêuticos/organização & administração , Pneumonia Viral/epidemiologia , Pneumonia Viral/prevenção & controle , População Rural , Doença Crônica , Serviços Comunitários de Farmácia , Florida , Humanos , Conduta do Tratamento Medicamentoso/organização & administração , Papel Profissional , Telemedicina
13.
Ned Tijdschr Geneeskd ; 1642020 06 04.
Artigo em Holandês | MEDLINE | ID: mdl-32608920

RESUMO

With the exception of a few medical specialties, the implementation of pharmacogenetic tests in daily practice has thus far been limited. The Royal Dutch Pharmacists Association (KNMP) has developed pharmacogenetics-based therapeutic doserecommendations for 80 medicinal product combinations on the basis of a systematic literature review. Genotyping of patients can take place on a reactive or pre-emptive basis; the advantage of pre-emptive genotyping is that it provides genetic information the moment a medicinal product is prescribed. Clinical decision support software is crucial to implement pharmacogenetics into daily practice.


Assuntos
Sistemas de Apoio a Decisões Clínicas , Prescrições de Medicamentos/normas , Farmacogenética/normas , Testes Farmacogenômicos/normas , Cálculos da Dosagem de Medicamento , Técnicas de Genotipagem , Humanos , Países Baixos , Farmacêuticos/organização & administração , Farmacogenética/métodos , Testes Farmacogenômicos/métodos , Revisões Sistemáticas como Assunto
15.
Ann Hematol ; 99(7): 1615-1625, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32483668

RESUMO

Ibrutinib treatment has been shown to increase survival in patients with B cell malignancies. Real-life data suggest a large part of discontinuations are due to toxicities, impairing ibrutinib efficacy. We aimed to assess the impact of a pharmaceutical care program on the efficacy and safety of ibrutinib. This single-center, cohort, observational study enrolled patients with B cell malignancies. Patients were either assigned to the program or to receive usual care, based on physician decision. The program was conducted by clinical pharmacists specializing in oncology and included patient education for management of toxicities, adherence monitoring, interventions to reduce drug-drug interactions, and follow-up of transition from hospital to community. Between February 2014 and May 2017, we enrolled 155 patients, including 42 (27%) who were allocated to the program group and 113 (73%) to the usual care group. The effect of the program was beneficial in terms of time to treatment failure (p = 0.0005). The 30-month progression-free and overall survivals were significantly superior in the program group (respectively p = 0.002 and p = 0.004). Grade 3 or higher adverse events occurred more frequently for patients in the usual care group (15%) than program group (8%). A pharmaceutical care program provides a personalized environment for outpatient monitoring and control of the key risks associated with oral anticancer agents. This study shows evidence that management of ibrutinib treatment by clinical pharmacists results in significant improvement in survival and better tolerance than usual care.


Assuntos
Neoplasias/tratamento farmacológico , Neoplasias/mortalidade , Assistência Farmacêutica/normas , Pirazóis/uso terapêutico , Pirimidinas/uso terapêutico , Melhoria de Qualidade , Tempo para o Tratamento/normas , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Eficiência Organizacional , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Assistência Farmacêutica/organização & administração , Assistência Farmacêutica/tendências , Farmacêuticos/organização & administração , Farmacêuticos/normas , Análise de Sobrevida , Fatores de Tempo , Tempo para o Tratamento/organização & administração , Tempo para o Tratamento/tendências , Falha de Tratamento
16.
Rev Med Suisse ; 16(697): 1210-1213, 2020 Jun 10.
Artigo em Francês | MEDLINE | ID: mdl-32520461

RESUMO

Polypharmacy is common in patients with a chronic disease. It is appropriate when both the patient and the physician discuss the goal of each prescribed medication with a motivated patient capable of managing his/her medication. It can however be inappropriate when treatment becomes too complex for the frail patient. The risk is non-adherence to therapy, which often results in an intensification of treatment due to unmet therapeutic goals. Collaboration between physicians and pharmacists is therefore essential for the educational support of patients with polypharmacy. In this article, we review the studies examining the impact of a physician-pharmacist collaboration on the medication adherence of diabetic patients with renal impairment.


Assuntos
Nefropatias Diabéticas/tratamento farmacológico , Nefropatias Diabéticas/psicologia , Adesão à Medicação , Farmacêuticos/organização & administração , Médicos/organização & administração , Humanos , Polimedicação
18.
Int J Clin Pharm ; 42(4): 1197-1206, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32524513

RESUMO

Background An infectious disease caused by a novel coronavirus (later called COVID-19) reached pandemic levels in 2020 and community pharmacists were involved in responding to this pandemic, also in Kosovo. Objectives To explore the experiences of community pharmacists in relation to provision of community pharmacy services during COVID-19 pandemic. Setting Community pharmacists in Kosovo. Methods This was a cross-sectional study where data was collected via a self-administered online questionnaire, from 264 pharmacists actively practicing in Kosovo during the pandemic. The questionnaire consisted of a combination of closed and open-ended questions, optional statements and statements on a five-point Likert scale, derived at least in part from the Transtheoretical Model. One-way analysis of variance was used to analyze differences in responses to Likert-type items whereas categorical variables were analyzed using Chi square testing. Main outcome measures Community pharmacists' perceptions on COVID-19 related preventative measures. Results A response rate of 40.6% was achieved. Sufficient and adequate COVID-19-related preventative measures were being implemented by a majority of pharmacies (n = 232; 87.9%), and over two-thirds of respondents agreed/strongly agreed that their pharmacies were sufficiently prepared with protective equipment for their personnel. Implementation of preventative measures was associated with respondents' perception that pharmacists and the pharmacy profession were valued more by patients during the pandemic and to a lesser degree, by other health professionals. Most commonly stated pros dealt with employee and patient safety, while key cons dealt with increased costs and running out of the necessary protective equipment. Key barriers to pharmacy activities were price increases by wholesalers, and patients' panic and excessive buying, whereas drivers dealt with professional obligation to assist and opportunity to prove inseparable to other health professionals. The most popular means of accessing COVID-19 related information by pharmacists was via mobile devices and information from professional organizations was considered most useful by pharmacists. Conclusions Community pharmacies actively implemented various measures as precautions to mitigate the spread of COVID-19. Our findings highlight the value of continuous provision of information by professional organizations and use of mobile devices as key means to access information by pharmacists.


Assuntos
Serviços Comunitários de Farmácia/organização & administração , Infecções por Coronavirus/prevenção & controle , Pandemias/prevenção & controle , Farmacêuticos/organização & administração , Pneumonia Viral/prevenção & controle , Telefone Celular/estatística & dados numéricos , Infecções por Coronavirus/epidemiologia , Estudos Transversais , Feminino , Humanos , Kosovo , Masculino , Pneumonia Viral/epidemiologia , Papel Profissional , Sociedades Farmacêuticas/estatística & dados numéricos , Inquéritos e Questionários
19.
J Oncol Pharm Pract ; 26(6): 1452-1460, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32525442

RESUMO

Lung cancer is a complex, genetically heterogeneous disease. It is the most common cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) represents the majority of the diagnosed lung cancer cases. Osimertinib is a new treatment option that demonstrated a superior efficacy over standard epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) or platinum-based chemotherapy. The safety and efficacy of osimertinib (a third generation EGFR-TKIs) were confirmed by well-designed clinical trials. Consequently, osimertinib was considered a first-line treatment option, particularly in patients with EGFR mutant NSCLC. It has been approved by FDA for the treatment of advance or metastatic NSCLC patients with specific EGFR-mutant NSCLC. As an active member of the multidisciplinary team, pharmacist has a promising role in assuring safe, effective and cost-effective treatment in patient with NSCLC. This review article aims to highlight the latest evidence about osimertinib use as a new treatment option in the clinical practice and to review the potential pharmacist key roles in NSCLC patient care.


Assuntos
Acrilamidas/administração & dosagem , Compostos de Anilina/administração & dosagem , Carcinoma Pulmonar de Células não Pequenas/tratamento farmacológico , Neoplasias Pulmonares/tratamento farmacológico , Receptores ErbB/antagonistas & inibidores , Humanos , Mutação , Farmacêuticos/organização & administração , Inibidores de Proteínas Quinases/uso terapêutico , Resultado do Tratamento
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