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1.
Rev. Asoc. Méd. Argent ; 132(3): 10-13, sept. 2019. graf
Artigo em Espanhol | LILACS | ID: biblio-1026856

RESUMO

El cigarrillo electrónico introduce un fuerte debate en el mercado con respecto a su intencionalidad de uso. El objetivo del presente trabajo es describir el grado de interés del término "cigarrillo electrónico" y la intencionalidad de su búsqueda en la Web en la Argentina. La herramienta que utilizamos fue el software libre de Google Trends. Las búsquedas en internet por parte de los usuarios estarían relacionadas con el consumo y no con la cesación. La vigilancia de consultas en la Web puede ser una herramienta innovadora en el control del tabaco, especialmente respecto de los dispositivos electrónicos administradores de nicotina.


The electronic cigarette introduces a strong debate in the market regarding its intentionality of use. The objective of the present work is to describe the degree of interest of the term "electronic cigarette" and the intentionality of its search in the Web in Argentina. The tool that we used was the free software of Google Trends. Internet searches by users would be related to the consumption and not with the cessation. The monitoring of web queries can be an innovative tool in tobacco control, especially in respect to the nicotine delivery system.


Assuntos
Humanos , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Fumar , Sistemas Eletrônicos de Liberação de Nicotina , Argentina , Ferramenta de Busca/tendências , Ferramenta de Busca/estatística & dados numéricos , Terminologia como Assunto
2.
Vet Clin North Am Exot Anim Pract ; 22(3): 539-548, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31395330

RESUMO

In recent years, there has been a dramatic change in how information can be disseminated in the scientific world. This is especially true for health care in general, and exotic pet practice hardly makes an exception. From the constant growth of online repositories that archives scholarly articles such as PubMed, to the creation of hashtags specific for health care that can be followed by millions of persons, we need to understand that communication is changing and that the proper use of modern technologies may result in an unprecedented era for knowledge retrieval and dissemination.


Assuntos
Animais Exóticos , Disseminação de Informação/métodos , Medicina Veterinária/métodos , Animais , Bases de Dados Bibliográficas , MEDLINE , Revisão por Pares , PubMed , Ferramenta de Busca , Mídias Sociais
3.
Stud Health Technol Inform ; 264: 1408-1412, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438158

RESUMO

To improve user experience, many health IT systems provide personalization options allowing end users to tailor the software to their needs and preferences. However, few studies have investigated if healthcare professionals actually make full use of this feature. As an initial step towards understanding end users' software personalization behavior in healthcare, we conducted a pilot study to examine how clinicians, staff, and researchers customized a search engine designed to facilitate information retrieval from electronic health records. The results show that a majority of the end users (82.4%) did not make an effort to modify the system's default settings. Among those who did, they more often changed its 'look-and-feel' than its functionality offerings. We conclude that future research is warranted to study the rationale underlying healthcare professionals' software personalization decisions both to optimize user experience and to avoid building complex and costly personalization options that are unused or underutilized.


Assuntos
Registros Eletrônicos de Saúde , Ferramenta de Busca , Humanos , Armazenamento e Recuperação da Informação , Projetos Piloto , Software
4.
Stud Health Technol Inform ; 264: 1439-1440, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438170

RESUMO

Clinical terms are noisy descriptions typed by healthcare professionals in Spanish language in the electronic health record system (EHR). Thus, an evaluation of terminology search engine that extends SNOMED CT and an approach that uses historical data of clinical terms is described. We show how to measure precision and recall using historical search data, and we show how the performance of the search engine can be improved significantly using the technology available in the search engine.


Assuntos
Registros Eletrônicos de Saúde , Ferramenta de Busca , Linguagem , Systematized Nomenclature of Medicine
5.
Stud Health Technol Inform ; 264: 1550-1551, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438226

RESUMO

We report on the pilot evaluation of an experimental query-based search functionality that enables phrase-level query rewriting in an unsupervised way. It is intended for supporting search in clinical text. Qualitative evaluation is done by three clinicans using a prototype search tool. They report that they find the tested search functionality to be beneficial for making query-based searching in clinical text more efficient.


Assuntos
Processamento de Linguagem Natural , Ferramenta de Busca , Redação
6.
Stud Health Technol Inform ; 264: 1564-1565, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438233

RESUMO

ICD-10 (International Classification of Diseases 10th revision) is a classification code for diseases, signs and symptoms, abnormal findings, complaints, social circumstances, and external causes of injury or diseases. This paper describes an automatic information retrieval approach to map free-text disease descriptions to ICD-10 codes. We use the Hospital Italiano de Buenos Aires (HIBA) terminology data mapped to ICD-10 codes as indexed data to find an appropriate ICD-10 code using search engine similarity metrics.


Assuntos
Armazenamento e Recuperação da Informação , Classificação Internacional de Doenças , Processamento Eletrônico de Dados , Ferramenta de Busca
7.
Facial Plast Surg ; 35(4): 387-392, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31412380

RESUMO

A growing number of patients are seeking answers for their health concerns online. This study assesses the reliability, quality, and readability of online materials patients have access to through the Internet and evaluates the social media presence of information providers. An online search was conducted for facial rejuvenation by utilizing three ubiquitously used web search engines: Google, Bing, and Yahoo. The first 25 result pages were collected from each search engine, and exclusionary criteria were applied to exclude online stores and advertisements. Website reliability and quality were assessed via the DISCERN method. Readability was measured through six measurements: Flesch-Kincaid Grade Level (FKGL), Gunning Fox score, SMOG index, Coleman Liau index, and automated readability index. Social media presence and profile followers on Facebook, Twitter, and Instagram were determined to gauge social media presence. Exclusionary criteria yielded 41 unique websites, with the majority of websites authored by physicians (54%) followed by professional organizations (19%). The DISCERN method demonstrated that journal websites yielded the highest overall quality (4.00) and physician websites yielded the lowest (2.72). Readability analysis demonstrated that online forums proved the most challenging to read, and encyclopedia articles were the least challenging. Physician websites maintained the highest social media presence (95%) followed by professional organizations (75%). However, professional organizations had more social media followers in comparison to physician websites. Physician websites and professional organizations overwhelmingly command social media presence compared to other information providers and provide information with serious deficits in reliability and quality. A strong majority of online information also surpasses the health care literacy of patients. This poses a serious concern for physicians who need to provide and guide patients to high quality and reliable information.


Assuntos
Compreensão , Informação de Saúde ao Consumidor , Internet , Rejuvenescimento , Humanos , Leitura , Reprodutibilidade dos Testes , Ferramenta de Busca
8.
Nat Methods ; 16(8): 703-706, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31363206

RESUMO

Proteins can be phosphorylated at neighboring sites resulting in different functional states, and studying the regulation of these sites has been challenging. Here we present Thesaurus, a search engine that detects and quantifies phosphopeptide positional isomers from parallel reaction monitoring and data-independent acquisition mass spectrometry experiments. We apply Thesaurus to analyze phosphorylation events in the PI3K/AKT signaling pathway and show neighboring sites with distinct regulation.


Assuntos
Fosfopeptídeos/análise , Fosfoproteínas/análise , Proteoma/análise , Ferramenta de Busca/métodos , Células HeLa , Humanos , Proteínas Substratos do Receptor de Insulina/metabolismo , Isomerismo , Células MCF-7 , Fosfatidilinositol 3-Quinases/metabolismo , Fosforilação , Proteínas Proto-Oncogênicas c-akt/metabolismo , Transdução de Sinais , Espectrometria de Massas em Tandem
9.
BMC Bioinformatics ; 20(1): 429, 2019 Aug 16.
Artigo em Inglês | MEDLINE | ID: mdl-31419935

RESUMO

BACKGROUND: Diagnosis and treatment decisions in cancer increasingly depend on a detailed analysis of the mutational status of a patient's genome. This analysis relies on previously published information regarding the association of variations to disease progression and possible interventions. Clinicians to a large degree use biomedical search engines to obtain such information; however, the vast majority of scientific publications focus on basic science and have no direct clinical impact. We develop the Variant-Information Search Tool (VIST), a search engine designed for the targeted search of clinically relevant publications given an oncological mutation profile. RESULTS: VIST indexes all PubMed abstracts and content from ClinicalTrials.gov. It applies advanced text mining to identify mentions of genes, variants and drugs and uses machine learning based scoring to judge the clinical relevance of indexed abstracts. Its functionality is available through a fast and intuitive web interface. We perform several evaluations, showing that VIST's ranking is superior to that of PubMed or a pure vector space model with regard to the clinical relevance of a document's content. CONCLUSION: Different user groups search repositories of scientific publications with different intentions. This diversity is not adequately reflected in the standard search engines, often leading to poor performance in specialized settings. We develop a search engine for the specific case of finding documents that are clinically relevant in the course of cancer treatment. We believe that the architecture of our engine, heavily relying on machine learning algorithms, can also act as a blueprint for search engines in other, equally specific domains. VIST is freely available at https://vist.informatik.hu-berlin.de/.


Assuntos
Neoplasias/patologia , Medicina de Precisão , Ferramenta de Busca , Algoritmos , Bases de Dados como Assunto , Documentação , Humanos , Internet , Interface Usuário-Computador
10.
J Laryngol Otol ; 133(7): 610-614, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31280728

RESUMO

OBJECTIVE: Many people seek health information from internet sources. Understanding this behaviour can help inform healthcare delivery. This study aimed to review Google Trends as a method for investigating internet-based information-seeking behaviour related to throat cancer in terms of quantity, content and thematic analysis. METHOD: Data was collected using Google Trends. Normalised data was created using the search terms 'throat cancer', 'cancer', 'HPV', 'laryngeal cancer' and 'head and neck cancer'. The search data was used to analyse the temporal and geographical interest pattern of these terms from 2004 to 2015. RESULTS: Three important peaks in searches for 'throat cancer' were identified. The first and greatest increase in interest was in September 2010, and there were also peaks in June 2013 and in October 2011. CONCLUSION: Internet-search analysis can provide an insight into the information-seeking behaviour of the public. Mass media can hugely affect this information-seeking behaviour. Possessing tools to investigate and understand information-seeking behaviour may be used to improve healthcare delivery.


Assuntos
Comportamento de Busca de Informação , Neoplasias Faríngeas , Ferramenta de Busca/tendências , Feminino , Humanos , Educação de Pacientes como Assunto
11.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 41(3): 388-395, 2019 Jun 30.
Artigo em Chinês | MEDLINE | ID: mdl-31282335

RESUMO

Objective To investigate the demand for scientific information among cervical cancer patients and to evaluate the quality of the relevant information available for these patients.Methods The demand for medical science information among patients with cervical cancer was investigated via questionnaire.The Discernn scoring system was used to score the cervical cancer science articles retrieved by Baidu and Sogou.A model was established to analyse the reading difficulty of these articles.Results Nearly half(53.6%)of the respondents searched for online science information at least weekly.The main target readings were the etiology and risk factors of diseases,symptoms,treatment options,adverse reactions of treatments,and prognosis.Most respondents(96.4%)thought that the network science information was reliable.Of the 104 search results included in the sample bank,13(12.5%)met the inclusion criteria,91(87.5%)were not selected,including 32 duplicates(30.8%),6 non-text webpages(5.8%),18 short texts(less than 300 Chinese characters)(17.3%),7 advertisements(6.7%),3 news articles(2.9%),22 forum posts(21.2%),and 3 academic articles(2.9%).According to the Discern scoring system,the reliability(r=0.728, P<0.001),the quality of treatment-related information(r=0.431, P<0.001),and the overall scores(r=0.559,P<0.001)of the enrolled 13 publications were consistent,as evaluated by two professional physicians.The mean overall score was 3.A lower score(less than 3)in the reliability assessment was due to the source of the content,generation methods,sponsors,citations,and the undefined parts.During the evaluation of treatment information,the average score was below 3 for each item.Analysis of the reading difficulty showed that,among these 13 articles,4 were at postgraduate thesis level(level 5),4 at undergraduate thesis level(level 4),0 at high school textbook level(level 3),and 8 was higher than middle school level(≥level 3).Eight articles(61.5%)were suitable for readers with an education background of higher middle school and only 5 articles(38.5%)were suitable for readers with an education background of middle school or lower(≤ level 2).Conclusions The vast majority of patients with cervical cancer search for clinical information through the Internet and trust their reliability.Chinese search engines have lower detection rates for high-quality medical science articles.The currently available high-quality medical science articles are small in number and difficult to read.More physicians are urged to write easy-to-read high-quality articles for these patients.


Assuntos
Necessidades e Demandas de Serviços de Saúde , Comportamento de Busca de Informação , Neoplasias do Colo do Útero , Feminino , Humanos , Internet , Reprodutibilidade dos Testes , Ferramenta de Busca , Inquéritos e Questionários
12.
Med Oral Patol Oral Cir Bucal ; 24(4): e461-e467, 2019 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-31246939

RESUMO

BACKGROUND: To assess the readability and quality of web-based information available for patients about oral lichen planus (OLP). MATERIAL AND METHODS: Three major search engines (Google, Bing and Yahoo!) were used to identify websites of particular interest to the study using the search term 'oral lichen planus'. The first 100 sites of each search engine were considered for the study. The quality of the contents was evaluated using the DISCERN instrument. The Flesch-Kinkaid Reading Grade Level (FKRGL) and the Flesh Reading Ease Score (FRES) were used to assess readability. The presence of the Health on the Net (HON) seal was also evaluated. RESULTS: Following the application of the study's exclusion criteria, only 28 websites were compiled for further analysis. The median of the DISCERN instrument was 3 [2-3] which means serious or potentially important shortcoming in the quality of the information. Readability indexes pointed to a high reading difficulty (FRES: 48.14±11.22; FKRGL:11.13±2.90). CONCLUSIONS: The information provided by the Internet to the general public regarding OLP has major deficits in terms of quality, and at the same time is difficult for a comprehensive reading. Further studies are warranted to test well-produced patient-centered information on OLP.


Assuntos
Compreensão , Líquen Plano Bucal , Humanos , Internet , Assistência Centrada no Paciente , Ferramenta de Busca
13.
Endocr Pract ; 25(10): 1003-1011, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31170373

RESUMO

Objective: This study evaluated online thyroid cancer patient information quality. This is essential, given increasing patient use of online health information. Methods: A total of 100 thyroid cancer websites, representing those patients find first, were identified using Google and two meta-search engines. Content accuracy and patient-evaluable quality markers, including attribution, currency, structure, and content comprehensiveness and readability, were assessed with a previously validated standardized rating tool, developed using design-based methods. Accuracy was defined compared to standard, peer-reviewed medical resources, UpToDate and the National Comprehensive Cancer Network. Responses to general and personal "patient" questions were evaluated for promptness and accuracy. Results: Of 100 websites, only 26% stated authorship, and 56% cited sources. Seventy-four percent had dates of creation or last update, with only half of those dates occurring within the past 2 years. Websites most often discussed the definition (94%), diagnosis (92%), and treatment (94%) of thyroid cancer, but diagnosis and treatment were also most frequently incomplete or inaccurate: diagnosis information was complete and accurate 50% of the time, and treatment 47%. Only 2% of websites were comprehensible without high school education. Of 83 websites contacted with "patient" questions, 50 replied, 48 within 1 week. Conclusion: Thyroid cancer information is widely available online, but quality varies. Sites often lack markers for patients to assess quality, and content may be difficult to understand. Information is frequently incomplete, particularly on topics important to patients, such as diagnosis and treatment. Educational resource developers may fill these gaps, and healthcare providers can direct thyroid cancer patients to reliable online resources. Abbreviation: NCCN = National Comprehensive Cancer Network.


Assuntos
Neoplasias da Glândula Tireoide , Compreensão , Humanos , Internet , Ferramenta de Busca
14.
Diagn. tratamento ; 24(2): [59-63], abr - jun 2019. tab, fig
Artigo em Português | LILACS | ID: biblio-1015338

RESUMO

Introdução: Com o crescimento contínuo das informações disponíveis na área da saúde, é fundamental que o profissional da saúde desenvolva habilidades e competências para realizar buscas de evidências cientificas. Objetivo: Apresentar as principais bases da área da saúde e os mecanismos de busca específicos para cada uma delas. Métodos: Estudo descritivo desenvolvido na Disciplina de Medicina Baseada em Evidências da Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp). Resultados: Este estudo apresentou os quatro passos do processo de busca em uma base de dados científica da área da saúde: (1) identificação da pergunta estruturada por meio dos acrônimos PICO/PECO, (2) escolha da base de dados (3) escolha e uso dos descritores em saúde apropriados para cada base (DeCS/MeSH/EMTREE) e (4) escolha e uso dos operadores booleanos (AND/OR/AND NOT). Conclusão: O processo de elaboração de uma estratégia de busca para bases de dados da área da saúde pode ser estruturado em quatro passos iniciais, que vão da identificação da pergunta estruturada ao uso dos operadores booleanos. Apropriar-se destes passos é fundamental para conseguir elaborar uma estratégia de busca adequada, capaz de recuperar os estudos de interesse e que abordem realmente a pergunta proposta.


Assuntos
Epidemiologia Descritiva , Bases de Dados Bibliográficas , Medicina Baseada em Evidências , Medical Subject Headings , Metodologia , Ferramenta de Busca
15.
PLoS Comput Biol ; 15(5): e1007022, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-31091224

RESUMO

Chemicals interact with genes in the process of disease development and treatment. Although much biomedical research has been performed to understand relationships among genes, chemicals, and diseases, which have been reported in biomedical articles in Medline, there are few studies that extract disease-gene-chemical relationships from biomedical literature at a PubMed scale. In this study, we propose a deep learning model based on bidirectional long short-term memory to identify the evidence sentences of relationships among genes, chemicals, and diseases from Medline abstracts. Then, we develop the search engine DigChem to enable disease-gene-chemical relationship searches for 35,124 genes, 56,382 chemicals, and 5,675 diseases. We show that the identified relationships are reliable by comparing them with manual curation and existing databases. DigChem is available at http://gcancer.org/digchem.


Assuntos
Distúrbios Induzidos Quimicamente/etiologia , Distúrbios Induzidos Quimicamente/genética , Doença/etiologia , Doença/genética , Ferramenta de Busca , Biologia Computacional , Mineração de Dados , Bases de Dados Factuais , Bases de Dados Genéticas , Aprendizado Profundo , Feminino , Humanos , MEDLINE , Masculino , PubMed
16.
Cyberpsychol Behav Soc Netw ; 22(6): 373-380, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31112038

RESUMO

Celebrity suicides that are reported heavily in the media may increase risk for others' suicidal behavior. This study examined whether Internet search volumes for suicide-related terms changed after three celebrity suicide deaths (Robin Williams, Chester Bennington, and Alexander McQueen) and three celebrities who died by means other than suicide (David Bowie, Azzedine Alaia, and Paul Walker). Suicide search terms included suicide, how to suicide, commit suicide, depression, hanging, and suicide prevention. Observed suicide search volumes in the United States were collected from Google Trends for the 10 weeks before and the 2 weeks following each celebrity's death. Predicted search volumes for the 14 days postdeath were forecasted from the predeath search volumes and predicted search volumes were then compared to the true, observed search volumes. Search volumes for suicide terms significantly increased following Robin Williams' suicide death. Some of the terms increased in search volume following Chester Bennington's and Alexander McQueen's suicide deaths, but not significantly. Most search volumes for nonsuicide celebrity deaths did not change following their deaths. Celebrity suicide deaths can lead to significant, national increases in Internet search volumes for suicide-related terms for celebrities of high prominence. Results highlight the critical importance of reporting suicide deaths in the media responsibly.


Assuntos
Pessoas Famosas , Internet/estatística & dados numéricos , Ferramenta de Busca/estatística & dados numéricos , Suicídio/psicologia , Navegador/estatística & dados numéricos , Depressão/psicologia , Feminino , Humanos , Masculino , Ideação Suicida
19.
BMC Bioinformatics ; 20(1): 255, 2019 May 17.
Artigo em Inglês | MEDLINE | ID: mdl-31101000

RESUMO

BACKGROUND: The Bioinformatics Resource Manager (BRM) is a web-based tool developed to facilitate identifier conversion and data integration for Homo sapiens (human), Mus musculus (mouse), Rattus norvegicus (rat), Danio rerio (zebrafish), and Macaca mulatta (macaque), as well as perform orthologous conversions among the supported species. In addition to providing a robust means of identifier conversion, BRM also incorporates a suite of microRNA (miRNA)-target databases upon which to query target genes or to perform reverse target lookups using gene identifiers. RESULTS: BRM has the capability to perform cross-species identifier lookups across common identifier types, directly integrate datasets across platform or species by performing identifier retrievals in the background, and retrieve miRNA targets from multiple databases simultaneously and integrate the resulting gene targets with experimental mRNA data. Here we use workflows provided in BRM to integrate RNA sequencing data across species to identify common biomarkers of exposure after treatment of human lung cells and zebrafish to benzo[a]pyrene (BAP). We further use the miRNA Target workflow to experimentally determine the role of miRNAs as regulators of BAP toxicity and identify the predicted functional consequences of miRNA-target regulation in our system. The output from BRM can easily and directly be uploaded to freely available visualization tools for further analysis. From these examples, we were able to identify an important role for several miRNAs as potential regulators of BAP toxicity in human lung cells associated with cell migration, cell communication, cell junction assembly and regulation of cell death. CONCLUSIONS: Overall, BRM provides bioinformatics tools to assist biologists having minimal programming skills with analysis and integration of high-content omics' data from various transcriptomic and proteomic platforms. BRM workflows were developed in Java and other open-source technologies and are served publicly using Apache Tomcat at https://cbb.pnnl.gov/brm/ .


Assuntos
Biologia Computacional/métodos , Genômica/métodos , Internet , MicroRNAs/genética , Biologia de Sistemas/métodos , Animais , Sequência de Bases , Humanos , Macaca mulatta , Camundongos , MicroRNAs/metabolismo , Proteômica , RNA Mensageiro/genética , Ratos , Ferramenta de Busca , Análise de Sequência de RNA , Especificidade da Espécie , Peixe-Zebra/genética
20.
Methods Mol Biol ; 1933: 397-414, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30945200

RESUMO

Experimentally validated plant lncRNAs have been shown to regulate important agronomic traits such as phosphate starvation response, flowering time, and interaction with symbiotic organisms, making them of great interest in plant biology and in breeding. We developed a pipeline to annotate lncRNAs and applied it to 37 plant species and 6 algae, resulting in the annotation of more than 120,000 lncRNAs. To facilitate the study of lncRNAs for the plant research community, the information gathered is organized in the Green Non-Coding Database (GreeNC, http://greenc.sciencedesigners.com/) . This chapter contains a detailed explanation of the content of GreeNC and how to access both programmatically and with a web browser.


Assuntos
Arabidopsis/genética , Biologia Computacional/métodos , Bases de Dados de Ácidos Nucleicos , Genoma de Planta , Anotação de Sequência Molecular , RNA Longo não Codificante/genética , RNA de Plantas/genética , Sequenciamento de Nucleotídeos em Larga Escala/métodos , Ferramenta de Busca , Análise de Sequência de RNA/métodos
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