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1.
Am J Dermatopathol ; 44(10): 774-777, 2022 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-36122337

RESUMO

ABSTRACT: Necrotizing infundibular crystalline folliculitis (NICF) is a rare distinct entity that was introduced in 1999. It typically presents with numerous eruptive waxy papules on the forehead and/or the upper back in adults in their fifth to seventh decade of life. The pathogenesis is unknown to date, but yeast and bacterial infection of the follicular ostia seems to contribute to the development. More recently, NICF has occasionally been observed as a side effect of targeted antitumoral therapy. Histopathologically, NICF is characterized by dilated follicular ostia filled with pale filamentous and birefringent material enclosed by parakeratotic columns of the epidermis and accompanied by a mild superficial inflammatory infiltrate of the dermis. This case report is about a 58-year-old male patient presenting with multiple eruptive keratotic papules on his forehead. Histopathology revealed all classic features of NICF. The case represents a classic example of NICF and is compared with previously published cases that are comprehensively summarized in this article.


Assuntos
Exantema , Foliculite , Adulto , Dorso/patologia , Foliculite/tratamento farmacológico , Foliculite/patologia , Humanos , Masculino , Pessoa de Meia-Idade
2.
Clin Exp Dermatol ; 47(11): 2022-2024, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-35699624

RESUMO

We present a rare case of eosinophilic pustular folliculitis due to mRNA-based vaccines for COVID-19. Histology of the biopsy specimen was very interesting.


Assuntos
Vacinas contra COVID-19 , COVID-19 , Foliculite , Humanos , COVID-19/prevenção & controle , Vacinas contra COVID-19/efeitos adversos , Foliculite/induzido quimicamente , Foliculite/patologia , Vacinação , Vacinas de mRNA/efeitos adversos
3.
Am J Dermatopathol ; 44(6): 395-403, 2022 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-35583404

RESUMO

ABSTRACT: Eosinophilic pustular folliculitis of infancy is a sterile, inflammatory dermatosis that mainly affects children younger than 36 months. The underlying physiopathologic mechanism is unclear. Clinical diagnosis is challenging, and a skin biopsy may be necessary. The literature data are sometimes contradictory, and a histologic series of eosinophilic pustular folliculitis of infancy cases has not been previously published.


Assuntos
Eosinofilia , Foliculite , Dermatopatias Vesiculobolhosas , Criança , Eosinofilia/patologia , Foliculite/diagnóstico , Foliculite/patologia , Humanos , Pele/patologia , Dermatopatias Vesiculobolhosas/diagnóstico , Dermatopatias Vesiculobolhosas/patologia
4.
BMJ Case Rep ; 15(3)2022 Mar 08.
Artigo em Inglês | MEDLINE | ID: mdl-35260404

RESUMO

Squamous cell carcinoma (SCC) is uncommon in African Americans (AAs), with an incidence of approximately 0.003%. However, it is the most common skin cancer in that patient population. In AAs, SCC typically arises in sun-protected areas and mainly affects patients older than 50 years. We report a case of giant SCC in an AA man in his 40s with long-standing folliculitis decalvans on the scalp. Three previous skin biopsies were inconclusive. A wide excision was performed and the defect was reconstructed with an anterolateral thigh free flap. Histological analysis of the resected specimen revealed a well-moderately differentiated keratinising SCC with clear cell changes, severe mixed inflammation, folliculitis and dermal scar. He was discharged 2 weeks later and has been followed up closely. Four months later, the patient presents with metastatic SCC to an occipital lymph node.


Assuntos
Carcinoma de Células Escamosas , Foliculite , Neoplasias de Cabeça e Pescoço , Neoplasias Cutâneas , Alopecia , Carcinoma de Células Escamosas/complicações , Carcinoma de Células Escamosas/patologia , Carcinoma de Células Escamosas/cirurgia , Foliculite/etiologia , Foliculite/patologia , Neoplasias de Cabeça e Pescoço/complicações , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Masculino , Couro Cabeludo/patologia , Couro Cabeludo/cirurgia , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgia
5.
Bol Med Hosp Infant Mex ; 79(1): 62-68, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35086132

RESUMO

BACKGROUND: Folliculitis due to Malassezia spp. (MF), caused mainly by Malassezia furfur, is clinically characterized by an acneiform eruption expressing follicular papules and pustules, predominantly on the trunk. Diagnosis of MF requires confirmation of the presence of yeasts in the hair follicle. The treatment of choice is topical or oral with azoles. We report two cases of folliculitis due to Malassezia spp. of atypical distribution in immunosuppressed patients. CASE REPORTS: Case 1. We describe a 14-year-old male patient diagnosed with chondroid osteosarcoma who required surgical treatment and chemotherapy. He was hospitalized for fever and neutropenia, presenting a rash of papulopustular lesions on the upper and lower extremities and neck. Direct examination and biopsy were performed to conclude the diagnosis of disseminated atypical Malassezia spp. folliculitis. Case 2. We describe a 16-year-old male patient diagnosed with synovial sarcoma, treated with surgical resection and chemotherapy. During hospitalization due to fever and neutropenia, he presented with disseminated dermatosis of the head, trunk, and upper extremities, showing multiple follicular papules and pustules with erythematous base; on the trunk, there were few lesions. In the supraciliary region, he showed erythema and furfuraceous desquamation. Direct examination of a follicle showed thick-walled round yeasts compatible with MF. CONCLUSIONS: MF is a frequent entity but of low diagnostic suspicion. Immunosuppressed patients may manifest atypical clinical characteristics in non-seborrheic areas, implying diagnostic difficulty. Biopsy and direct examination are essential to corroborate the etiology in patients with immunosuppression or with a non-classical presentation.


INTRODUCCIÓN: La foliculitis por Malassezia spp., causada principalmente por Malassezia furfur, se caracteriza clínicamente por una erupción acneiforme, con pápulas y pústulas foliculares de predominio en el tronco. El diagnóstico requiere confirmar la presencia de las levaduras en el folículo piloso. El tratamiento de elección es tópico u oral con azoles. Se reportan dos casos de foliculitis por Malassezia spp. de distribución atípica en pacientes inmunosuprimidos. CASOS CLÍNICOS: Caso 1. Paciente de sexo masculino de 14 años con diagnóstico de osteosarcoma condroide que ameritó tratamiento quirúrgico y quimioterapia. Fue hospitalizado por fiebre y neutropenia, presentando una erupción con lesiones papulopustulosas en las extremidades superiores e inferiores y en el cuello. Se realizaron examen directo y biopsia para concluir el diagnóstico de foliculitis por Malassezia spp. atípica diseminada. Caso 2. Paciente de sexo masculino de 16 años con diagnóstico de sarcoma sinovial, tratado con resección quirúrgica y quimioterapia, hospitalizado por fiebre y neutropenia. Presentó dermatosis diseminada en la cabeza, el tronco y las extremidades superiores, con múltiples pápulas y pústulas foliculares con base eritematosa; en el tronco había escasas lesiones. En la región supraciliar mostró eritema y escama furfurácea. Se realizó examen directo de un folículo, que reportó levaduras redondas de pared gruesa, compatibles con foliculitis por Malassezia spp. CONCLUSIONES: La foliculitis por Malassezia spp. es una afección frecuente, pero de poca sospecha diagnóstica. En pacientes inmunosuprimidos puede manifestarse con una clínica atípica en áreas no seborreicas, lo que implica la dificultad del diagnóstico. La biopsia y el examen directo son fundamentales para corroborar la etiología en pacientes con inmunosupresión o con expresión no clásica.


Assuntos
Dermatomicoses , Foliculite , Malassezia , Neutropenia , Adolescente , Biópsia , Dermatomicoses/diagnóstico , Dermatomicoses/tratamento farmacológico , Foliculite/diagnóstico , Foliculite/tratamento farmacológico , Foliculite/patologia , Humanos , Masculino
7.
Am J Dermatopathol ; 43(12): 867-870, 2021 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-34735106

RESUMO

ABSTRACT: Necrotizing infundibular crystalline folliculitis is a rare entity, which is a distinctive clinical and histopathological entity. Eruptive yellow waxy umbilicated folliculocentric plugs clinically correspond to pale crystalline filaments embedded in an amorphous sebum-rich material. Remarkably, only the superficial infundibular ostia remain, and the distended cavity is devoid of a follicular or sebaceous gland remnant. The pathogenesis of this enigmatic event remains to be established. The emergence of necrotizing infundibular crystalline folliculitis (NICF) as a paradoxical side effect of antitumor inhibitors epidermal growth factor receptor vascular endothelial growth factor and more recently programmed death-1 represents the expression of altered molecular pathways that underpin the pathogenesis of NICF. To explore these pathways, it is necessary to explore the hierarchy of follicular stem cells, particularly the potential role of committed infundibular stem cells that play a key role in wound healing. Committed infundibular stem cells are closely linked to the sebaceous gland stem cell axis, and this has relevance in the process of homeostatic repair of sebaceous follicles in the wake of folliculitis. The unscheduled modulation of this infundibular homeostatic sebaceous repair axis by epidermal growth factor receptor vascular endothelial growth factor, and programmed death-1 may lead to an aberrant outcome with metaplasia of infundibular keratinocytes to sebocytes. In the absence of sebaceous gland differentiation, these metaplastic infundibular sebocyte cells would lead to the consumption and loss of the infundibulum as a result of holocrine sebum production. This conceptual pathogenic pathway for NICF is constructed by incorporating recent advances in the fields of follicular stem cells, wound repair, follicular homeostasis, regulatory T cells, and molecular pathways linked to the biologicals inducing NICF.


Assuntos
Foliculite/patologia , Folículo Piloso/patologia , Células-Tronco/patologia , Inibidores da Angiogênese/efeitos adversos , Antineoplásicos/efeitos adversos , Foliculite/induzido quimicamente , Folículo Piloso/efeitos dos fármacos , Humanos , Inibidores de Checkpoint Imunológico/efeitos adversos , Glândulas Sebáceas/patologia , Células-Tronco/efeitos dos fármacos , Fator A de Crescimento do Endotélio Vascular/antagonistas & inibidores
8.
J Allergy Clin Immunol ; 148(2): 473-485.e10, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-33713763

RESUMO

BACKGROUND: Neutrophilic folliculitis is an inflammatory condition of hair follicles. In some neutrophilic folliculitis, such as in patients with acne and hidradenitis suppurativa, follicular hyperkeratosis is also observed. Neutrophilic folliculitis is often induced and/or exacerbated by a high-fat diet (HFD). However, the molecular mechanisms by which an HFD affects neutrophilic folliculitis are not fully understood. OBJECTIVE: Our aim was to elucidate how an HFD promotes the development of neutrophilic folliculitis. METHODS: Mice were fed an HFD, and their skin was subjected to histologic, RNA sequencing, and imaging mass spectrometry analyses. To examine the effect of an HFD on neutrophil accumulation around the hair follicles, phorbol 12-myristate 13-acetate (PMA) was used as an irritant to the skin. RESULTS: Histologic analysis revealed follicular hyperkeratosis in the skin of HFD-fed mice. RNA sequencing analysis showed that genes related to keratinization, especially in upper hair follicular keratinocytes, were significantly upregulated in HFD-fed mice. Application of PMA to the skin induced neutrophilic folliculitis in HFD-fed mice but not in mice fed a normal diet. Accumulation of neutrophils in the skin and around hair follicles was dependent on CXCR2 signaling, and CXCL1 (a CXCR2 ligand) was produced mainly by hair follicular keratinocytes. Imaging mass spectrometry analysis revealed an increase in fatty acids in the skin of HFD-fed mice. Application of these fatty acids to the skin induced follicular hyperkeratosis and caused PMA-induced neutrophilic folliculitis even in mice fed a normal diet. CONCLUSION: An HFD can facilitate the development of neutrophilic folliculitis with the induction of hyperkeratosis of hair follicles and increased neutrophil infiltration around the hair follicles via CXCR2 signaling.


Assuntos
Dieta Hiperlipídica/efeitos adversos , Foliculite/imunologia , Folículo Piloso/imunologia , Hiperceratose Epidermolítica/imunologia , Infiltração de Neutrófilos/efeitos dos fármacos , Animais , Suscetibilidade a Doenças/induzido quimicamente , Suscetibilidade a Doenças/imunologia , Suscetibilidade a Doenças/patologia , Foliculite/induzido quimicamente , Foliculite/patologia , Folículo Piloso/patologia , Hiperceratose Epidermolítica/induzido quimicamente , Hiperceratose Epidermolítica/patologia , Inflamação/induzido quimicamente , Inflamação/imunologia , Inflamação/patologia , Masculino , Camundongos
9.
J Cutan Pathol ; 48(3): 439-450, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33617128

RESUMO

Within the literature, there is overlap in the histopathological features described in eosinophilic folliculitis associated with chronic lymphocytic leukemia (CLL), eosinophilic dermatosis of hematologic malignancy, and acneiform follicular mucinosis. These disorders are described with varying degrees of superficial and deep lymphocytic and eosinophilic inflammation demonstrating perivascular, perifollicular, and folliculocentric involvement with or without follicular mucin deposition. Given significant histopathological overlap, these diagnoses may represent a continuum on a spectrum of dermatoses. Here, we present two cases with histopathological elements that reflect components of this clinicopathological spectrum and compare our findings with previously reported cases to compare and contrast reported features. Our first case is a 71-year-old African American man with long-standing CLL who developed a pruritic erythematous papular eruption on the face and chest with biopsy revealing a dense folliculotropic lymphocytic infiltrate with conspicuous eosinophils and follicular mucinosis. Our second case is a 70-year-old Caucasian man recently diagnosed with CLL/small lymphocytic lymphoma who developed an erythematous papular rash on the neck and face with biopsy revealing superficial and deep perivascular and periadnexal lymphocytic inflammation with scattered eosinophils. Characterization of our two cases and comparison with available literature suggest that these disorders may represent a continuum of dermatoses.


Assuntos
Eosinofilia/patologia , Eosinófilos/patologia , Foliculite/patologia , Neoplasias Hematológicas/patologia , Leucemia Linfocítica Crônica de Células B/patologia , Linfoma Cutâneo de Células T/patologia , Mucinose Folicular/patologia , Dermatopatias Vesiculobolhosas/patologia , Dermatopatias/patologia , Erupções Acneiformes/patologia , Administração Tópica , Corticosteroides/administração & dosagem , Corticosteroides/uso terapêutico , Adulto , Idoso , Idoso de 80 Anos ou mais , Anti-Inflamatórios/administração & dosagem , Anti-Inflamatórios/uso terapêutico , Biópsia , Diagnóstico Diferencial , Eosinofilia/tratamento farmacológico , Foliculite/tratamento farmacológico , Neoplasias Hematológicas/complicações , Humanos , Leucemia Linfocítica Crônica de Células B/complicações , Linfoma Cutâneo de Células T/complicações , Masculino , Pessoa de Meia-Idade , Mucinose Folicular/tratamento farmacológico , Prednisona/administração & dosagem , Prednisona/uso terapêutico , Dermatopatias/tratamento farmacológico , Dermatopatias/imunologia , Dermatopatias Vesiculobolhosas/tratamento farmacológico , Resultado do Tratamento
11.
Am J Dermatopathol ; 43(4): 298-299, 2021 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-33156024

RESUMO

ABSTRACT: Patients with eosinophilic pustular folliculitis (EPF), a sterile eosinophilic infiltration of hair follicles, often present with papulopustules that tend to form annular plaques. Histopathologic examination revealed eosinophilic infiltration around the pilosebaceous units and eosinophilic microabscess formation. Although the pathogenesis of EPF is unknown, T-helper type 2 immune responses were suggested to be important based on their stimulating effect on the sebaceous glands. Here, we report the first case of EPF associated with herpes zoster, indicating that herpes zoster and EPF are correlated with T-helper type 2 immune responses.


Assuntos
Eosinofilia/patologia , Foliculite/patologia , Herpes Zoster/patologia , Herpesvirus Humano 3/patogenicidade , Dermatopatias Vesiculobolhosas/patologia , Pele/patologia , Eosinofilia/tratamento farmacológico , Eosinofilia/imunologia , Eosinofilia/virologia , Feminino , Foliculite/tratamento farmacológico , Foliculite/imunologia , Foliculite/virologia , Herpes Zoster/imunologia , Herpes Zoster/virologia , Herpesvirus Humano 3/imunologia , Antagonistas dos Receptores Histamínicos/uso terapêutico , Interações Hospedeiro-Patógeno , Humanos , Pele/efeitos dos fármacos , Pele/imunologia , Pele/virologia , Dermatopatias Vesiculobolhosas/tratamento farmacológico , Dermatopatias Vesiculobolhosas/imunologia , Dermatopatias Vesiculobolhosas/virologia , Esteroides/uso terapêutico , Células Th2/imunologia , Resultado do Tratamento , Adulto Jovem
14.
Int J Occup Environ Med ; 11(4): 210-212, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-33098405

RESUMO

Folliculitis is a common skin disease, usually benign, which causes inflammation and eventual infections of hair follicles. They may have an infectious etiology, mainly due to the bacteria Staphylococcus aureus; it also occurs due to localized irritation, such as in areas of skin friction and for long periods of immersion in water, as in athletes and workers who are continuously exposed to the aquatic environment. Herein, we report on two fishermen, from fluvial and maritime environments, who presented with chronic aseptic folliculitis associated with daily immersion of their lower extremities while exercising the profession and that regressed when there was a decrease in their contact with water.


Assuntos
Foliculite/microbiologia , Foliculite/patologia , Folículo Piloso/microbiologia , Infecções Estafilocócicas/patologia , Staphylococcus aureus/isolamento & purificação , Adulto , Água Doce , Folículo Piloso/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Infecções Estafilocócicas/microbiologia
15.
Dermatol Ther ; 33(6): e14465, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-33112028

RESUMO

Acquired perforating dermatosis (APD) is a group of a rare dermatological disorder characterized by elimination of dermal connective tissue through epidermis. We aimed to evaluate the characteristics of patients diagnosed with APD and to determine the differences in comorbidities according to subtypes of APD. A retrospective, observational, cross-sectional study was designed. Patients diagnosed with APD between January 2008 and January 2019 were reviewed. Eighty patients were included in the study. 61.2% (n = 49) of the patients were female and 38.8% (n = 31) were male with a mean age of 58.4 ± 12.5 years. 82.5% (n = 66) of the patients were diagnosed with reactive perforating collagenosis (RPC) and 17.5% (n = 14) of perforating folliculitis (PF). The most common concomitant disease was diabetes mellitus (82.5%). 5.0% of the patients had malignancy. The comorbidity rate in RPC group was higher than PF (P < .05). Topical steroid was the most frequently (90.0%) used treatment. Complete response was obtained 55.0% of patients. Exitus was observed in 23.8% (n = 19) of patients in a mean 17.6 ± 25.7 months follow-up period. APD may be associated with many diseases. Comorbidities are more frequent in RPC group. This situation warns us to evaluate patients with RPC in more detail for underlying diseases. High mortality rate related to the underlying systemic diseases suggests being careful in terms of mortality in patients diagnosed with APD.


Assuntos
Foliculite , Dermatopatias , Idoso , Estudos Transversais , Epiderme , Feminino , Foliculite/tratamento farmacológico , Foliculite/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Dermatopatias/diagnóstico , Dermatopatias/tratamento farmacológico , Dermatopatias/patologia
16.
Int J Dermatol ; 59(12): 1468-1474, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33040344

RESUMO

BACKGROUND: An association between wearing protective gear and eosinophilic folliculitis has not been reported. We aimed to investigate such during the COVID-19 pandemic. METHODS: In three outpatient clinics, we hand-reviewed records of all patients having consulted us during a Study Period (90 days) in the early phase of the pandemic. Our inclusion criteria for Study Subjects were: (i) clear clinical diagnosis, (ii) dermoscopic confirmation, (iii) differential diagnoses excluded, (iv) eosinophilia, (v) protective gear worn during sanitation services, (vi) temporal correlation, (vii) distributional correlation, (viii) physician-assessed association, and (ix) patient-assessed association. Control Periods in the same season were elected. RESULTS: Twenty-five study subjects fulfilled all inclusion criteria. The incidence was significantly higher than in the control periods (IR: 3.57, 95% CI: 1.79-7.43). Male predominance was significant (P < 0.001). Such for patients in the control periods were insignificant. Study subjects were 21.2 (95% CI: 11.0-31.4) years younger than patients in the control periods. For the study subjects, the distribution of erythematous or skin-colored folliculocentric dome-shaped papules and pustules were all compatible with body parts covered by the gear. Lesional biopsy performed on two patients revealed eosinophilic dermal infiltrates within and around the pilosebaceous units. Polarized dermoscopy revealed folliculitis with peri-/interfollicular vascular proliferation. Lesion onsets were 6.4 (SD: 2.1) days after wearing gear. Remissions were 16.7 (SD: 7.5) days after ceasing to wear gear and treatments. CONCLUSIONS: Wearing protective gear in volunteered sanitizing works could be associated with eosinophilic folliculitis. Owing to the significant temporal and distributional correlations, the association might be causal.


Assuntos
Controle de Doenças Transmissíveis/métodos , Infecções por Coronavirus/prevenção & controle , Eosinofilia/epidemiologia , Foliculite/epidemiologia , Pandemias/prevenção & controle , Equipamento de Proteção Individual/efeitos adversos , Pneumonia Viral/prevenção & controle , Dermatopatias Vesiculobolhosas/epidemiologia , Voluntários/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Betacoronavirus/patogenicidade , Biópsia , COVID-19 , Controle de Doenças Transmissíveis/instrumentação , Controle de Doenças Transmissíveis/normas , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/virologia , Dermoscopia , Diagnóstico Diferencial , Eosinofilia/diagnóstico , Eosinofilia/etiologia , Eosinofilia/patologia , Feminino , Foliculite/diagnóstico , Foliculite/etiologia , Foliculite/patologia , Folículo Piloso/diagnóstico por imagem , Folículo Piloso/patologia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Pneumonia Viral/epidemiologia , Pneumonia Viral/virologia , Estudos Retrospectivos , Fatores de Risco , SARS-CoV-2 , Saneamento , Fatores Sexuais , Dermatopatias Vesiculobolhosas/diagnóstico , Dermatopatias Vesiculobolhosas/etiologia , Dermatopatias Vesiculobolhosas/patologia , Fatores de Tempo , Adulto Jovem
19.
Dermatol Online J ; 26(5)2020 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-32621704

RESUMO

Pseudolymphomatous folliculitis is a benign entity that is included within pseudolymphomas. Because of its rapid clinical growth and suspicious histology it has to be differentiated from malignant entities. Given its low frequency, the dermatoscopic characteristics of this entity are not well-characterized and have been described only once previously. We present a middle-aged woman with a facial erythematous plaque of 6 months' evolution, with dermatoscopy in which follicular plugs on an erythematous base were appreciated. The histology showed a dense lymphocytic infiltrate with folliculotropism and follicular alteration, with numerous peripheral histiocytes positive for S100 and CD1a. The lesion partially disappeared after the biopsy, and completely after topical treatment.


Assuntos
Foliculite/patologia , Pseudolinfoma/patologia , Dermatopatias/patologia , Adulto , Dermoscopia , Diagnóstico Diferencial , Feminino , Humanos , Pessoa de Meia-Idade , Pele/patologia
20.
Am J Case Rep ; 21: e920728, 2020 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-32669532

RESUMO

BACKGROUND Obesity is one of the leading causes of preventable death worldwide. Due to its increasing incidence and the difficulty in reducing its morbidity and mortality using nonsurgical methods, the demand for bariatric surgery has risen in recent times. Sleeve gastrectomy is one of the most common types of bariatric surgery, and like any other surgery, it carries a series of risks. CASE REPORT Although complications such as gastrointestinal leaks are widely reported, there is limited literature available on cutaneous complications. Here, we report 4 cases of patients showing a peculiar skin rash 2-4 weeks following sleeve gastrectomy. We also discuss some of the mechanisms that may underlie this correlation. CONCLUSIONS There is a need for further epidemiological studies to determine the prevalence of this rash. Further studies are also needed to determine the exact etiology of this rash.


Assuntos
Dermatite/diagnóstico , Exantema/etiologia , Foliculite/diagnóstico , Gastrectomia , Complicações Pós-Operatórias , Adulto , Dermatite/patologia , Exantema/patologia , Feminino , Foliculite/patologia , Humanos , Masculino
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