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1.
Braz. j. oral sci ; 20: e219280, jan.-dez. 2021. ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1254266

RESUMO

Aim: To evaluate the effect of manual (M), electric (E) and ultrasonic (US) toothbrushes on the removal of oral biofilm and control of gingivitis. Also, the roughness and tooth wear production were evaluated in vitro. Methods: For the in vitro analyses, thirty bovine dentin specimens were submitted to a 3-month brushing simulation (9 minutes) with the three types of toothbrushes (n = 10). Subsequently, a randomized controlled clinical trial was performed with 36 patients divided into 3 groups according to the toothbrushes used (n = 12). Gingival index, visible plaque index and the volume of crevicular fluid were evaluated at baseline and 3 months after the beginning of the toothbrush use. Furthermore, the performance of the biofilm removal per brushing cycle of 1 and 3 minutes with each toothbrush was made monthly until the end of the experiment. Results: The US group had the highest dentin wear. Clinically, the US group had a lower plaque index at 3 months than the M group. The M group also showed less biofilm removal efficiency from the second month of follow-up and more worn bristles at the end of the 3 month period than the E and US groups. Conclusion: The ultrasonic, electric and manual toothbrushes showed no differences in gingivitis control in the present study. The ultrasonic and electric toothbrushes had a more significant effect on biofilm removal than a manual toothbrush, but the ultrasonic toothbrush promoted greater dentin tissue wear


Assuntos
Humanos , Masculino , Feminino , Higiene Bucal , Escovação Dentária , Gengivite
2.
Am J Orthod Dentofacial Orthop ; 160(5): 648-658, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34752255

RESUMO

INTRODUCTION: The aim of this single-blinded, parallel-group, randomized clinical trial was to compare the efficacy of electric 3-dimensional (3D) toothbrushes and manual toothbrushes in removing plaque and reducing gingival inflammation in orthodontic patients. METHODS: Eighty adolescents with fixed orthodontic appliances in both arches were randomized at a 1:1 ratio, with an equal number of both sexes, in this examiner blinded, parallel clinical trial. Eligibility criteria included subjects aged between 12 and 16 years, good general health, nonextraction orthodontic treatment, and plaque-induced gingivitis, excluding patients with active caries or periodontitis, tooth agenesis, syndromes, disabilities, and craniofacial deformities, ≥2 cervical and/or proximal fillings, dental prostheses or dental implants, and subjects smoking or using antibiotics or medication predisposing to gingival enlargement. Patients were assigned to use either an electric 3D orthodontic toothbrush (Oral-B Pro-1000 with Oral-B Ortho head; Procter & Gamble, Cincinnati, Ohio) or a manual toothbrush (Oral-B Orthodontic brush; Procter & Gamble) and instructed to brush twice daily for 2 minutes. The main outcomes were: (1) plaque removal, assessed with the Modified Silness and Löe plaque index and the Modified Full Mouth Plaque Score, and (2) gingival inflammation reduction, assessed with the Modified Silness and Löe Gingival Index and the Modified Simplified Gingival Index. Measurements were taken at baseline, 1, 2, and 3 months. Randomization was achieved with 2 random sequences, one for each brush, written and sealed in opaque numbered envelopes. Blinding was possible for outcome assessment only. RESULTS: Considerable variability was observed among patients in the values of all dependent variables. There was no difference between interventions over time for any of the outcomes, and the main effects for treatment and time were also not statistically significant. For Modified Silness and Löe plaque index, the interaction was 0.001 (95% confidence interval, -0.011 to 0.013; P = 0.89). CONCLUSIONS: No difference in plaque removal efficacy and gingival inflammation reduction was found between the electric 3D and manual toothbrushes in adolescents with fixed orthodontic appliances. Therefore, orthodontists should focus on enhancing their patients' dental awareness and oral hygiene, along with professional prophylaxis and other oral hygiene aids, independently of the brush used. REGISTRATION: This trial was registered at ClinicalTrials.gov (Identifier: NCT02699931). PROTOCOL: The protocol was not published before trial commencement. FUNDING: Electric and manual toothbrushes and toothpastes for all participants were provided by Procter & Gamble (Oral-B). Miscellaneous costs were covered by the participating departments.


Assuntos
Gengivite , Saúde Bucal , Escovação Dentária , Adolescente , Criança , Índice de Placa Dentária , Desenho de Equipamento , Feminino , Gengivite/etiologia , Gengivite/prevenção & controle , Humanos , Masculino , Aparelhos Ortodônticos/efeitos adversos , Aparelhos Ortodônticos Fixos/efeitos adversos , Método Simples-Cego , Escovação Dentária/instrumentação , Escovação Dentária/métodos
3.
Int J Syst Evol Microbiol ; 71(10)2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34751644

RESUMO

A Gram-negative bacterium, designated strain Marseille-Q3452T, was isolated from subgingival dental plaque of a subject suffering from dental plaque biofilm-induced gingivitis on an intact periodontium in Marseille, France. The strain was characterized by 16S rRNA and atpA gene sequence analysis and by conventional phenotypic and chemotaxonomic testing. The average nucleotide identity (ANI) and core genome phylogeny were determined using whole-genome sequences. Although strain Marseille-Q3452T showed 99.72 % 16S rRNA gene sequence similarity with Campylobacter showae strain ATCC 51146T, atpA and ANI analyses revealed divergence between the two strains. The two species could also be distinguished phenotypically on the basis of the absence of flagella and nitrate reduction. On the basis of the results from phenotypic, chemotaxonomic, genomic and phylogenetic analyses and data, we concluded that strain Marseille-Q3452T represents a novel species of the genus Campylobacter, for which the name Campylobacter massiliensis sp. nov. is proposed (=CSUR Q3452=CECT 30263).


Assuntos
Campylobacter , Gengivite , Técnicas de Tipagem Bacteriana , Composição de Bases , Campylobacter/genética , DNA Bacteriano/genética , Ácidos Graxos/química , Humanos , Filogenia , RNA Ribossômico 16S/genética , Análise de Sequência de DNA
4.
Int J Syst Evol Microbiol ; 71(10)2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34612809

RESUMO

A Gram-stain-negative bacterium, designated strain Marseille-Q3039T, was isolated from subgingival dental plaque of a woman with gingivitis in Marseille, France. Strain Marseille-Q3039T was found to be an anaerobic, motile and spore-forming crescent-shaped bacterium that grew at 25-41.5 °C (optimum, 37 °C), pH 5.5-8.5 (optimum, pH 7.5) and salinity of 5.0 g l-1 NaCl. The results of 16S rRNA gene sequence analysis revealed that strain Marseille-Q3039T was closely related to Selenomonas infelix ATCC 43532T (98.42 % similarity), Selenomonas dianae ATCC 43527T (97.25 %) and Centipedia periodontii DSM 2778T (97.19 %). The orthologous average nucleotide identity and digital DNA-DNA hybridization relatedness between strain Q3039T and its closest phylogenetic neighbours were respectively 84.57 and 28.2 % for S. infelix ATCC 43532T and 83.93 and 27.2 % for C. periodontii DSM 2778T. The major fatty acids were identified as C13 : 0 (27.7 %), C15 : 0 (24.4 %) and specific C13 : 0 3-OH (12.3 %). Genome sequencing revealed a genome size of 2 351 779 bp and a G+C content of 57.2 mol%. On the basis of the results from phenotypic, chemotaxonomic, genomic and phylogenetic analyses and data, we concluded that strain Marseille-Q3039T represents a novel species of the genus Selenomonas, for which the name Selenomonas timonae sp. nov. is proposed (=CSUR Q3039=CECT 30128).


Assuntos
Gengivite , Selenomonas , Técnicas de Tipagem Bacteriana , Composição de Bases , DNA Bacteriano/genética , Ácidos Graxos/química , Humanos , Filogenia , RNA Ribossômico 16S/genética , Análise de Sequência de DNA
5.
Compend Contin Educ Dent ; 42(9): e1-e4, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34606293

RESUMO

The objective of this study was to compare the antigingivitis and antiplaque efficacy of an oral hygiene system versus a control regimen. This was a single-center, randomized, examiner-blind, two-treatment, 12-week parallel group study in adults with evidence of gingivitis and plaque. Eligible subjects were stratified by baseline gingivitis and plaque scores, number of bleeding sites, and tobacco use and randomized to one of two treatment groups: (1) oral hygiene system (test group) involving a novel smart-connected Oral-B® iO oscillating-rotating (O-R) electric toothbrush, 0.454 percent stabilized stannous fluoride (SnF2) dentifrice, 0.07 percent cetylpyridinium chloride (CPC) rinse, and floss, or (2) control regimen involving a manual toothbrush and 0.243 percent sodium fluoride dentifrice. Gingivitis (modified gingival index, gingival bleeding index) and plaque (Rustogi modification of the navy plaque index) were assessed at Baseline, Week 1, and Week 12.


Assuntos
Placa Dentária , Dentifrícios , Gengivite , Adulto , Placa Dentária/prevenção & controle , Índice de Placa Dentária , Desenho de Equipamento , Gengivite/prevenção & controle , Humanos , Higiene Bucal , Método Simples-Cego , Escovação Dentária
6.
Ned Tijdschr Tandheelkd ; 128(10): 475-478, 2021 Oct.
Artigo em Holandês | MEDLINE | ID: mdl-34709001

RESUMO

For patients with fixed orthodontic appliances, adequate daily dental plaque removal is more difficult. As a result, dental plaque accumulates more quickly and gingivitis and white spots develop more often. In non-orthodontic patients, electric toothbrushing is more effective in dental plaque removal than a manual toothbrush. This structured literature review shows that there is limited evidence that electric toothbrushes are more effective in plaque removal than a manual toothbrush in patients with fixed orthodontic appliances.


Assuntos
Placa Dentária , Gengivite , Placa Dentária/prevenção & controle , Índice de Placa Dentária , Gengivite/etiologia , Humanos , Aparelhos Ortodônticos , Aparelhos Ortodônticos Fixos , Índice Periodontal , Método Simples-Cego , Escovação Dentária
7.
Artigo em Inglês | MEDLINE | ID: mdl-34682572

RESUMO

Essential oil (EO)-based mouthwashes have been used for oral health maintenance due to their antimicrobial and anti-inflammatory properties. The aim was to review clinical trials that assessed the role of EO-based mouthwashes in controlling gingivitis in patients undergoing fixed orthodontic treatment (OT). The Patients, Interventions, Control and Outcome (PICO) format was based on the following: (a) P: Patients undergoing fixed OT (b) Intervention: EO-based mouth-wash; Control: Mouthwashes that did not contain EOs or no mouthwash (d) Outcome: Control of gingivitis measured by clinical indices. Databases were searched manually and electronically up to and including May 2021 using different medical subject subheadings. Data screening and extraction were performed. The risk of bias within randomized controlled trials was assessed using the revised Cochrane Collaboration's risk of bias tool (RoB 2). The Risk of Bias In Non-randomized Studies-of Interventions (ROBINS-I) tool was used for non-randomized controlled trials. Disagreements related to literature search and RoB evaluations were resolved via discussion. Six clinical studies were included. Four studies showed that Listerine® is effective in controlling gingivitis in patients undergoing fixed OT. One study reported that the use of 5% Fructus mume mouthwash resulted in a significant reduction in gingival bleeding. Two mouthwashes that contained 1% Matricaria chamomilla L. and 0.5% Zingiber officinale were also found to be efficient in controlling gingival bleeding. Four, one and one studies had a low, moderate and high RoB, respectively. In conclusion, EO-based mouthwashes seem to be effective for the management of gingivitis among patients undergoing fixed OT. Further well-designed and power-adjusted clinical trials are needed.


Assuntos
Gengivite , Óleos Voláteis , Antibacterianos , Hemorragia Gengival , Gengivite/prevenção & controle , Humanos , Antissépticos Bucais/uso terapêutico , Óleos Voláteis/uso terapêutico
8.
Oral Health Prev Dent ; 19(1): 565-572, 2021 Jan 07.
Artigo em Inglês | MEDLINE | ID: mdl-34673848

RESUMO

PURPOSE: This study aimed to investigate whether treatment of gingivitis in pregnant women affects pregnancy outcomes. MATERIALS AND METHODS: This was a systematic review and meta-analysis of clinical trials using PRISMA guidelines to appraise the treatment of gingivitis on pregnancy outcomes, including preterm birth (less than 37 weeks), low birth weight (less than 2,500 g), gestational age and birth weight. Pooled odds ratios (OR), mean difference, and 95% confidence intervals (CI) were calculated using the random effect model. A search was conducted in databases including Medline, Pubmed, Web of Science, Google Scholar and Embase without restrictions regarding language or date of publication. RESULTS: Three clinical trials comprising 1,031 participants were included in this review. Treatment of gingivitis during pregnancy was associated with a decreased risk of preterm birth (OR = 0.44, 95% CI [0.20-0.98], P = 0.045) and higher birth weight (weighted mean difference (WMD) =105.36 g, 95% CI [36.72-174.01], P = 0.003). Gestational age at birth in the treatment group (WMD = 0.31 weeks, 95% CI [-0.02-0.64], P = 0.64) as well as likelihood of low birth weight (OR = 0.92, 95% CI [0.38-2.21], P = 0.851) did not reach statistical significance. CONCLUSION: The results of this meta-analysis indicate that treatment of gingivitis in pregnancy may improve pregnancy outcomes including increased infants birth weight and reduced preterm births. Future trials are warranted to validate the true effect size of gingivitis treatment on pregnancy outcomes.


Assuntos
Gengivite , Nascimento Prematuro , Feminino , Idade Gestacional , Gengivite/terapia , Humanos , Recém-Nascido de Baixo Peso , Recém-Nascido , Gravidez , Resultado da Gravidez
9.
PLoS One ; 16(10): e0258109, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34618843

RESUMO

PURPOSE: Previous studies have found that Epstein-Barr virus (EBV) is associated with periodontitis, though some controversy remains. This meta-analysis aimed to clarify and update the relationship between EBV and periodontitis as well as clinical parameters. METHODS: A comprehensive search was conducted in the PubMed and Scopus databases in December 2020. Original data were extracted according to defined inclusion and exclusion criteria. Outcomes were analyzed, including overall odds ratios (ORs) and 95% confidence intervals (CIs). A random-effects model was used, and publication bias was assessed by Egger's and Begg's tests. Sensitivity analysis was used to evaluate the stability of the outcome. RESULTS: Twenty-six studies were included in the present meta-analysis, involving 1354 periodontitis patients and 819 healthy controls. The included studies mostly showed high quality. The overall quantitative synthesis for the association between EBV and periodontitis was an increased odds ratio when subgingival EBV was detected OR = 7.069, 95% CI = 4.197-11.905, P<0.001). The results of subgroup analysis suggested that the association of EBV with periodontitis was significant in Asian, European, and American populations (P<0.001; P = 0.04; P = 0.003, respectively) but not in African populations (P = 0.29). Subgroup analysis by sample type showed that subgingival plaque (SgP), tissue and gingival crevicular fluid GCF were useful for EBV detection (P<0.001). EBV detection amplification methods included nested PCR, multiplex PCR and PCR (P<0.001; P = 0.05, P<0.001, respectively), but EBV detection by real-time PCR and loop-mediated isothermal amplification presented no significant result (P = 0.06; P = 0.3, respectively). For the clinical parameters of periodontitis, pocket depth (PD) and bleeding of probing (BOP) percentages were higher in the EBV-positive sites than in the EBV-negative sites (MD 0.47 [0.08, 0.85], P = 0.02; MD 19.45 [4.47, 34.43], P = 0.01). CONCLUSIONS: A high frequency of EBV detection is associated with an increased risk of periodontitis. The EBV association was particularly significant in all populations except in African populations. Subgigival plaque (SgP), tissue and GCF were not significantly different useful material for detecting EBV in periodontitis. Nested PCR and multiplex PCR are reliable methods for this purpose. In the presence of EBV, PD and BOP are reliable clinical parameters for gingival inflammation. However, some caution in such interpretation is justified due to heterogeneity among studies. A suggested extension could assess the parallel influence of other human herpesviruses.


Assuntos
Infecções por Vírus Epstein-Barr/genética , Gengivite/epidemiologia , Herpesvirus Humano 4/patogenicidade , Periodontite/epidemiologia , Adulto , Citomegalovirus/isolamento & purificação , Citomegalovirus/patogenicidade , DNA Viral/genética , Infecções por Vírus Epstein-Barr/complicações , Infecções por Vírus Epstein-Barr/epidemiologia , Infecções por Vírus Epstein-Barr/virologia , Feminino , Líquido do Sulco Gengival/virologia , Gengivite/genética , Gengivite/patologia , Gengivite/virologia , Herpesvirus Humano 4/genética , Humanos , Masculino , Pessoa de Meia-Idade , Técnicas de Diagnóstico Molecular , Técnicas de Amplificação de Ácido Nucleico , Periodontite/genética , Periodontite/patologia , Periodontite/virologia
10.
BMC Oral Health ; 21(1): 441, 2021 09 12.
Artigo em Inglês | MEDLINE | ID: mdl-34511098

RESUMO

BACKGROUND: This examiner-blind, stratified, parallel study aimed to evaluate the anti-gingivitis efficacy of a non-aqueous (anhydrous) 0.454% w/w stannous fluoride toothpaste ('Test') versus a sodium monofluorophosphate toothpaste ('Control') in people with clinically-confirmed mild-moderate gingivitis. Plaque-induced gingivitis can progress to irreversible periodontitis if left untreated. This can be controlled by an effective oral hygiene regimen such as one including toothbrushing with a toothpaste containing the chemotherapeutic agent stannous fluoride. Long-term studies over 4-12 weeks have shown the efficacy of stannous fluoride; however, shorter term studies are needed to examine if the effects on measures of gingivitis and plaque control occur sooner. METHODS: Eligible participants were randomised to 3 weeks' twice-daily brushing (for 1 min) with Test or Control toothpastes. The primary efficacy variable was between-treatment difference in Bleeding Index (BI) at 3 weeks; secondary variables were between-treatment differences in number of bleeding sites, modified Gingival Index (MGI), and Turesky modification of the Quigley-Hein Plaque Index (TPI) at Weeks 2 and 3. RESULTS: A statistically significant (p < 0.0001) lower BI score was reported for Test (n = 65) versus Control (n = 65) groups at Week 2 (mean difference: - 0.07 [95% CI - 0.9, - 0.05]; 32.7% difference) and Week 3 (mean difference: - 0.06 [95% CI - 0.8, - 0.04]; 29.2% difference). The Test group also demonstrated statistically significant lower (all p < 0.0001 versus Control) number of bleeding sites (Weeks 2/3 mean difference [95% CI]: - 10.04 [- 12.3, - 7.5]/ - 8.2 [- 11.1, - 5.3] sites; 33.0%/29.3% difference); MGI score (Weeks 2/3 mean difference [95% CI]: - 0.09 [- 0.13, - 0.06]/ - 0.10 [- 0.14, - 0.06]; 4.3%/4.7% difference); overall TPI score (Weeks 2/3 mean difference [95% CI]: - 0.45 [- 0.55, - 0.35/ - 0.42 [- 0.53, - 0.30] difference; 16.0%/15.1% difference) and interproximal TPI score (Weeks 2/3 mean difference [95% CI]: - 0.42 [- 0.52, - 0.30]/ - 0.41 [- 0.52, - 0.29]; 14.6%/14.1% difference). Both toothpastes were generally well tolerated. CONCLUSION: Three weeks' twice-daily brushing with the 0.454% w/w stannous fluoride Test toothpaste compared to the Control toothpaste led to statistically significant lower gingival bleeding, gingival inflammation and plaque levels in adults with mild-moderate gingivitis. These results indicate that plaque and gingivitis-reducing benefits of 0.454% w/w stannous fluoride may be seen from 2 weeks' use. Trial registration ClinicalTrials.gov Identifier: NCT04050722; 08/08/2019.


Assuntos
Placa Dentária , Gengivite , Adulto , Placa Dentária/prevenção & controle , Índice de Placa Dentária , Método Duplo-Cego , Gengivite/tratamento farmacológico , Gengivite/prevenção & controle , Humanos , Fluoretos de Estanho/uso terapêutico , Cremes Dentais/uso terapêutico
11.
BMC Oral Health ; 21(1): 452, 2021 09 17.
Artigo em Inglês | MEDLINE | ID: mdl-34535102

RESUMO

BACKGROUND: Chronic erosive gingivitis, also called desquamative gingivitis, defines a clinical picture that can be generated by several inflammatory and immune diseases. Pathology is therefore essential for the differential diagnosis. However, when the gingival lesion is initial, exclusive or predominant, selecting the biopsy site and protocol may be problematic due to tissue fragility. Especially since there are few studies on the subject, the aim of our study was to assess the protocol, diagnostic relevance and tolerance of an original protocol using interdental papilla biopsy. METHODS: We conducted a retrospective bicentric study, from October 2011 to July 2019, including all patients with a chronic erosive gingivitis who had received, for diagnostic purposes, a interdental papilla biopsy. RESULTS: The contribution levels for the two hospital departments were 94.7% and 97.1%, respectively. No postoperative complication was recorded in the short or long term. CONCLUSION: The interdental papilla biopsy protocol is perfectly adapted to the anatomopathological examinations required to establish differential diagnosis of chronic erosive gingivitis. This surgical protocol is simple to perform, non iatrogenic with a very good tolerance and and accessible to all clinicians. It is highly efficient with an excellent contribution level. ClinicalTrials NCT04293718 (March 3, 2020). Health Data Hub N° F20201109083211 (November 9, 2020).


Assuntos
Gengiva , Gengivite , Biópsia , Diagnóstico Diferencial , Gengivite/diagnóstico , Humanos , Estudos Retrospectivos
12.
Evid Based Dent ; 22(3): 91-93, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-34561655

RESUMO

Aim This study evaluates the available clinical evidence with regards to the effectiveness of mechanical oral hygiene devices in patients who are in periodontal maintenance.Data sources A structured online search was conducted in PubMed/Medline, Cochrane Central Register of Controlled Trials (CENTRAL) and Embase. All the databases were explored from initiation to October 2019. Reference lists of all the included studies were hand-searched as well.Study selection Randomised clinical trials or controlled clinical trials were included in this systematic review if the participants were adult patients (≥18 years) in the maintenance phase of treatment with no systemic disorder. The scope of included studies was to assess the effects of manual toothbrushes (MTBs) and powered toothbrushes (PTBs) or interdental brushes (IDBs) on dental plaque removal and other parameters of periodontitis and gingivitis. These parameters were as follows: plaque index score (PI), bleeding on probing, clinical attachment level (CAL), gingival index (GI), probing pocket depth (PPD), gingival index (GI) and gingival recession (REC).Data extraction and synthesis The Cochrane Handbook for Systematic Reviews of Interventions (2011) and the recommendations for strengthening the reporting of systematic reviews and meta-analyses (PRISMA) were both applied to extract data (with regards to population, intervention, comparison and outcomes) in this systematic review. A network meta-analysis (NMA) was performed to compare (either directly or indirectly) the studies that shared (at least) a common treatment. Treatments were then ranked using frequentist weighted least squares method. This was done based on the standardised mean difference of end plaque scores for each oral hygiene device. Finally, the authors provided a clinical significance assessment of study results using distribution-based methods.Results In the 16 included trials, 17 comparisons were selected to be assessed. In comparisons between PTBs and MTBs, 80% of them found no difference with respect to improving clinical parameters (four out of five). When adjunctive effect of an oral irrigator (OI) in addition to regular hygiene was evaluated, 66% (two out of three) of comparisons showed a positive significant effect on the GI, bleeding index scores and PPD in favour of using an OI. In 50% of comparisons (two out of four) concerning PI reduction, IDBs showed significantly better results than dental floss. This finding was endorsed by the authors' clinical significance assessment. Indirect results of the NMA ranked the cylindrical and conical IDBs as the best oral hygiene devices (compared to MTBs) in removing interdental plaque.Conclusions Considering the dearth of evidence that met the inclusion criteria for each oral hygiene device and the low certainty of the resultant findings, no definite conclusion could be drawn to recommend any device as the best option to use in periodontal maintenance patients. Yet, according to indirect evidence, it was found that IDBs, as adjuvants to tooth brushing, could significantly improve PI reduction compared with merely using MTBs.


Assuntos
Placa Dentária , Gengivite , Adulto , Placa Dentária/prevenção & controle , Índice de Placa Dentária , Gengivite/prevenção & controle , Humanos , Higiene Bucal , Escovação Dentária
13.
Evid Based Dent ; 22(3): 98-99, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-34561658

RESUMO

Data sources PubMed, CENTRAL, Scopus and Cochrane electronic databases were used as the data sources for the systematic review. All randomised control trials that reviewed antiseptics published up to and including 26 February 2019 were included. A manual search of reference lists of the selected studies was conducted, including information from previous systematic reviews conducted by the same authors.Study selection Two trained and calibrated reviewers screened titles and abstracts that investigated the efficacy of adjuncts to mechanical plaque control, in systematically healthy patients aged 18 years or older with dental plaque biofilm-induced gingivitis, in an intact periodontium (GP) or in patients previously treated for periodontitis with gingival inflammation (PP_GI). Studies with at least one test group and a control group were included, where changes from baseline up to six months in gingival or bleeding indices was the primary outcome.Data extraction and synthesis Data was extracted by three reviewers and reported outcomes extracted at baseline, six months and the longest to follow-up visit. Meta-analysis was conducted for six-month data on antiseptics investigating gingival indices, bleeding indices and plaque indices. Studies were compared via mean treatment effect, calculated for baseline to six months, and analysed using weighted mean differences (WMD) or standardised mean differences (SMD). Statistical heterogeneity was assessed using Cochran's Q and I squared statistic. Study-specific estimates were pooled using the random-effect model and meta-regression analysis performed. Sensitivity analysis was performed to assess the contribution of each study to the evidence and Begg's rank correlation test utilised to assess publication bias.Results Following screening of 1,101 articles, 70 were included in quantitative synthesis. Adjuncts yielded statistically significant reductions in gingival index, plaque index and plaque. Meta-regression analysis showed use of mouth rinses resulted in greater reductions in plaque when compared with dentifrices, whereas antiseptic agents were similarly effective in reducing gingivitis in plaque in patients with GP and PP_GI.Conclusions Based on the present evidence, adjunctive antiseptics in mouth rinses and dentifrices demonstrate statistically significant reductions in gingival, bleeding and plaque indices, when used in adjunct to mechanical plaque control. Clinical significance must be interpreted with caution due to the heterogeneity among studies included and significant publication bias.


Assuntos
Anti-Infecciosos Locais , Placa Dentária , Gengivite , Placa Dentária/prevenção & controle , Índice de Placa Dentária , Gengivite/prevenção & controle , Humanos , Antissépticos Bucais/uso terapêutico
14.
J Evid Based Dent Pract ; 21(3): 101575, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34479675

RESUMO

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Grender J, Adam R, Zou Y. The effects of oscillating-rotating electric toothbrushes on plaque and gingival health: A meta-analysis. Am J Dent. 2020 Feb;33(1):3-11. PMID: 32,056,408. SOURCE OF FUNDING: Industry (Procter & Gamble Company). TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data.


Assuntos
Gengivite , Escovação Dentária , Adulto , Índice de Placa Dentária , Desenho de Equipamento , Gengivite/prevenção & controle , Humanos , Índice Periodontal , Método Simples-Cego
15.
Artigo em Inglês | MEDLINE | ID: mdl-34501683

RESUMO

Desquamative gingivitis (DG) denotes a heterogeneous immune-mediated disease for which early diagnosis represents a great challenge. The main aim of this study is to validate diagnostic concordance between specific Optical Coherence Tomography (OTC) patterns for DG related to oral Lichen Planus (OLP), Pemphigus Vulgaris (PV), and Mucous Membrane Pemphigoid (MMP) and definitive histological diagnosis. Forty-three patients with suspected immune-mediated DGs, were progressively recruited. Before biopsy, an OCT preliminary evaluation was performed using specific pre-determined OCT diagnostic patterns (i.e., morphology and localization of blisters, status of the basal membrane, epithelial thickness, presence/absence of acantholytic cells into blister and/or inflammatory infiltrate) related to OLP, PV and MMP. After histological confirmation, OCT and histological diagnoses were compared. Using pre-determined patterns, OCT diagnoses of DGs were: 22 (51%) OLP, of which 11 (26%) were with the bullous variant, 4 (9%) PV and 6 (14%) MMP. The same diagnoses were found by histological investigations (with the main OCT discriminatory potential for the bullous variant of OLP). The concordance between the two diagnostic methods was confirmed by the Fisher exact test (p-value < 0.01). These specific OCT patterns show a diagnostic reliability in 100% of the cases investigated, suggesting their accuracy to support the complex diagnosis and management of immune-mediated DGs.


Assuntos
Gengivite , Penfigoide Mucomembranoso Benigno , Pênfigo , Humanos , Reprodutibilidade dos Testes , Tomografia de Coerência Óptica
16.
Int J Dent Hyg ; 19(4): 382-397, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34529340

RESUMO

OBJECTIVES: To evaluate the efficacy of the Triple bristles three-sided sonic powered toothbrush in plaque removal and its impact on tooth shade and gingival health, and to compare this with a conventional manual toothbrush. METHODS: Fifty two participants (26 males and 26 females; mean age [SD] = 22.48 [1.52], SE = 0.210, 95% CI = 22.06-22.90) were recruited into this controlled within-subject, randomized, two-treatment, 1-month crossover and examiner-blinded observational study between October 2020 and January 2021 in the School of Dentistry, University of Jordan. Within each participant, the upper and lower jaws were randomized to receive a brushing protocol either with the Triple bristles three-sided sonic brush or with a soft manual standard toothbrush with flat trimmed bristles. Tooth shades were recorded for upper and lower anterior and premolar teeth. The Turesky-Modified Quigley-Hein Plaque Index (TMQHPI) and bleeding on probing (BOP) were evaluated at study baseline, 1 week and 1 month after applying the brushing protocol. RESULTS: Both tested brushes were associated with significant reduction in plaque scores and BOP (p < 0.05). The Triple bristles brush was more effective in reduction in plaque and BOP in the lower jaw and among females than the manual brush (p < 0.05). CONCLUSIONS: The Triple bristles brush was more superior for reduction in plaque and probing on bleeding in the lower jaw and among females.


Assuntos
Placa Dentária , Gengivite , Placa Dentária/prevenção & controle , Desenho de Equipamento , Feminino , Humanos , Masculino , Método Simples-Cego , Escovação Dentária
17.
Int J Mol Sci ; 22(17)2021 Aug 26.
Artigo em Inglês | MEDLINE | ID: mdl-34502159

RESUMO

Down syndrome (DS) is a genetic disorder associated with early-onset periodontitis and other periodontal diseases (PDs). The present work aimed to systematically review the scientific literature reporting studies in vivo on oral microbiota features in subjects with DS and related periodontal health and to highlight any correlation and difference with subjects not affected by DS, with and without PDs. PubMed, Web of Science, Scopus and Cochrane were searched for relevant studies in May 2021. The participants were subjects affected by Down syndrome (DS) with and without periodontal diseases; the study compared subjects with periodontal diseases but not affected by DS, and DS without periodontal diseases; the outcomes were the differences in oral microbiota/periodontopathogen bacterial composition among subjects considered; the study design was a systematic review. Study quality was assessed with risk of bias in non-randomized studies of interventions (ROBINS-I). Of the 954 references retrieved, 26 studies were considered. The conclusions from the qualitative assessment of the papers revealed an increasing knowledge over the last years of the microbiota associated with DS and their periodontal diseases, in comparison with healthy subjects and subjects with other kinds of mental disabilities. Few data have emerged on the mycobiome and virobiome of DS, hence, further investigations are still necessary.


Assuntos
Síndrome de Down/complicações , Microbiota , Boca/microbiologia , Doenças Periodontais/complicações , Biofilmes , Placa Dentária/microbiologia , Gengivite/etiologia , Humanos
18.
Chin J Dent Res ; 24(3): 167-175, 2021 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-34491011

RESUMO

OBJECTIVE: To analyse the subgingival microbiota of Stage I/II periodontitis, gingivitis with different degrees of severity, and periodontal health in subjects in a Chinese young adult population. METHODS: Subgingival plaque samples were collected from 15 Stage I/II periodontitis patients, 38 gingivitis patients and 15 periodontally healthy individuals, all aged from 18 to 21 years. Gingivitis patients were divided into two subgroups according to the Bleeding Index (BI) of their sampled teeth: gingivitis with above median BI (G-HBI) and below median BI (G-LBI). The subgingival plaque samples were collected from teeth 16, 26, 36, 46, 11 and 31 according to FDI notation. The V3-V4 region of the 16S rRNA gene of all the samples was sequenced and analysed. RESULTS: The Stage I/II periodontitis, gingivitis and periodontal health groups showed distinct subgingival microbiota profiles. When the gingivitis patients were stratified into two subgroups, the community structure of G-HBI showed no significant difference from early-stage periodontitis, but differed from G-LBI and the healthy group. Most periodontitis-related taxa were most abundant in Stage I/II periodontitis, followed by G-HBI, G-LBI and the periodontally healthy group. Porphyromonas gingivalis, Filifactor alocis, Tannerella forsythia, Saccharibacteria TM7 G-5 356, Lachnospiraceae G-8 500, Peptostreptococcaceae spp. and Syntrophomonadaceae VIIIG-1 435 were associated with Stage I/II periodontitis. Porphyromonas 275, Leptotrichia 417 and Saccharibacteria TM7 G-2 350 were associated with gingivitis. Porphyromonas gingivalis was significantly more abundant in G-HBI than in G-LBI. CONCLUSION: Within the limitations of this preliminary study, gingivitis and early-stage periodontitis were associated with an increased degree of dysbiosis in the subgingival microbiota in a Chinese young adult population.


Assuntos
Gengivite , Periodontite , China , Clostridiales , Nível de Saúde , Humanos , Porphyromonas gingivalis/genética , RNA Ribossômico 16S/genética
19.
Georgian Med News ; (316-317): 70-73, 2021.
Artigo em Russo | MEDLINE | ID: mdl-34511448

RESUMO

Objective - to study the effect of braces on the dentoalveolar system and the occurrence of changes in the body as a whole. The study involved 25 patients, 15 women and 10 men aged 20 to 45 years, with an anomaly of occlusion of the dentition in the transversal and sagittal plane, crowded position of the teeth of the upper and lower dentition. All patients were treated orthodontically on the MBT prescription bracket system made of high-quality steel grade 17-4. In patients, the bracket system was fixed to the light (double) curing adhesive ENLIGHT by ORMCO. All patients signed an informed consent form. Orthodontic braces are used to treat dental anomalies. Increased microbial contamination (poor hygiene) due to the appearance of additional retention points for plaque, trauma to the oral mucosa with parts of orthodontic devices, invagination and infringement of the gingival papilla by moving teeth are the main factors in the development of gingivitis, periodontitis and cheilitis during treatment with a bracket system. As a result of the study, it was revealed that the proteins of non-specific immunity sIgA and lysozyme were studied in the mixed saliva of patients with a fixed metal bracket system. It was found that in 40% of patients after 3 months. after treatment, local immunodeficiency develops, which requires antibacterial therapy and professional oral hygiene in these terms. In conclusion, it is noted that braces have both positive and negative effects on the dental system and the body as a whole, so when planning orthodontic treatment, patients with initially reduced local immunity of the oral cavity should be included in the risk group.


Assuntos
Gengivite , Braquetes Ortodônticos , Periodontite , Feminino , Humanos , Masculino , Saliva
20.
Sci Rep ; 11(1): 17775, 2021 09 07.
Artigo em Inglês | MEDLINE | ID: mdl-34493783

RESUMO

Macropod progressive periodontal disease (MPPD) is a necrotizing, polymicrobial, inflammatory disease commonly diagnosed in captive macropods. MPPD is characterized by gingivitis associated with dental plaque formation, which progresses to periodontitis and then to osteomyelitis of the mandible or maxilla. However, the underlying microbial causes of this disease remain poorly understood. In this study, we collected 27 oral plaque samples and associated clinical records from 22 captive Macropodidae and Potoroidae individuals that were undergoing clinical examination at Adelaide and Monarto Zoos in South Australia (15 healthy, 7 gingivitis and 5 periodontitis-osteomyelitis samples). The V3-V4 region of the 16S ribosomal RNA gene was sequenced using an Illumina Miseq to explore links between MPPD and oral bacteria in these animals. Compositional differences were detected between the microbiota of periodontitis-osteomyelitis cases compared to healthy samples (p-value with Bonferroni correction < 0.01), as well as gingivitis cases compared to healthy samples (p-value with Bonferroni correction < 0.05) using Permutational Multivariate Analysis of Variance (PERMANOVA). An overabundance of Porphyromonas, Fusobacterium, and Bacteroides taxa was also identified in animals with MPPD compared to healthy individuals using linear discriminant analysis effect size (LEfSe; p = < 0.05). An increased abundance of Desulfomicrobium also was detected in MPPD samples (LEfSe; p < 0.05), which could potentially reflect differences in disease progression. This is the first microbiota analysis of MPPD in captive macropods, and these results support a polymicrobial pathogenesis of MPPD, suggesting that the microbial interactions underpinning MPPD may be more complex than previously documented.


Assuntos
Bacteroides/isolamento & purificação , Placa Dentária/veterinária , Fusobacterium/isolamento & purificação , Gengivite/veterinária , Macropodidae/microbiologia , Microbiota , Periodontite/veterinária , Porphyromonas/isolamento & purificação , Potoroidae/microbiologia , Animais , Animais de Zoológico/microbiologia , Biodiversidade , Coinfecção , Placa Dentária/microbiologia , Progressão da Doença , Gengivite/microbiologia , Doenças Mandibulares/microbiologia , Doenças Mandibulares/veterinária , Doenças Maxilares/microbiologia , Doenças Maxilares/veterinária , Osteomielite/microbiologia , Osteomielite/veterinária , Periodontite/microbiologia , Austrália do Sul
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