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1.
BMJ ; 366: l4915, 2019 08 27.
Artigo em Inglês | MEDLINE | ID: mdl-31455630

RESUMO

The studyA Rodger, V Cambiano, T Bruun, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet 2019;393:2428-38.This project was funded by the NIHR Research for Patient Benefit Programme (project number PB-PG-1013-32069).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000785/antiretroviral-treatment-can-reduce-the-risk-of-hiv-transmission-between-male-partners-to-zero.


Assuntos
Infecções por HIV , Minorias Sexuais e de Gênero , HIV , Humanos , Masculino , Estudos Prospectivos , Parceiros Sexuais
3.
Stud Health Technol Inform ; 264: 1347-1351, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438145

RESUMO

The goal of this study was to illustrate the translation of our extant eHealth intervention (VIP) into an mHealth app for persons living with HIV (PLWH) with HIV-Associated non-AIDS (HANA) conditions, a new clinical problem. We integrated different quantitative and qualitative methodologies from different disciplines to accomplish the task of adapting an eHealth system for a new set of clinical problems. Building off of our past development of the VIP website, we used a multi-modal, iterative user-centered design process to develop the VIP-HANA app. Our process was used to better understand the needs of a national sample of PLWH recruited online. Findings from the usability evaluation demonstrate a potentially useful and easy to use app. Integration of multi-modal methodologies from different fields to accomplish the tasks of adaptation and evaluation of a mobile app is an appealing, rigorous and useful approach.


Assuntos
Infecções por HIV , Aplicativos Móveis , Telemedicina , HIV , Humanos , Motivação
4.
Zhongguo Shi Yan Xue Ye Xue Za Zhi ; 27(4): 1287-1290, 2019 Aug.
Artigo em Chinês | MEDLINE | ID: mdl-31418394

RESUMO

OBJECTIVE: To investigate the methods for verifying and comparing performance of HIV testing methods and procedure analysis in blood station laboratories so as to meet the requirements of ISO15189 accreditation. METHODS: The performance of HIV test was verified by the automatic ELISA analyzer, the intra- and inter-assay precision was analyzed and evaluated by intra- and inter-assay repeat tests, the compliance rate was verified by the test results of the standard serum plate and the external quality assessment from the Ministry of Health in the past 2 years, the limit of detection was verified through continuous dilution of a known amount of reference serum for internal quality control, the status of the instrument was evaluated by testing one HIV-negative specimen, one HIV-negative with other positive markers, one strong HIV-positive specimen and two weak HIV-positive specimens. RESULTS: The intra- and inter-assay precisions were 5.12% and 16.81% respectively, the compliance rate of the serum plate test was 100%, the compliance of the external quality assessment results was 100%, the limits of detection for HIV was 1.42 NCU/ml, and the consistency of the detection systems was 100%. CONCLUSION: The analytical performance of the HIV test methods and procedures accords with the requirements of the reagent instructions, the comparison of the test systems meets the verification requirements.


Assuntos
HIV , Programas de Rastreamento , Ensaio de Imunoadsorção Enzimática , Controle de Qualidade , Testes Sorológicos
5.
6.
Rev. pesqui. cuid. fundam. (Online) ; 11(4): 868-872, jul.-set. 2019. tab, graf
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem | ID: biblio-1005607

RESUMO

Objetivo: Conhecer a vulnerabilidade dos adolescentes sobre o risco de contrair HIV/AIDS, vivenciada pelos adolescentes do ensino médio de uma rede pública no município de Riachão do Dantas/SE. Métodos: Pesquisa transversal, de natureza quantitativa. A amostra foi constituída por 204 adolescentes na faixa etária entre 14 e 18 anos que responderam um questionário estruturado (Ministério da Saúde/Ministério da Educação) intitulado: Eu preciso fazer o teste do HIV/AIDS? Resultados: Os resultados identificaram que 62% dos adolescentes do gênero masculino entrevistados já haviam iniciado a prática sexual enquanto que do gênero feminino, 38%. Observou-se uma vulnerabilidade considerável entre os adolescentes ao HIV; 67,6% estão em situação de vulnerabilidade, sendo que 82,9% destes adolescentes são do gênero masculino. Conclusão: Observa-se a necessidade de intensificar a atenção à saúde dos adolescentes nas escolas, oferecendo aos jovens informações sobre a prevenção dos agravos relativos à atividade sexual


Objective: To know the vulnerability of adolescents to the risk of contracting HIV / AIDS, experienced by high school adolescents of a public network in the municipality of Riachão do Dantas / SE. Methods: This is a cross-sectional, quantitative research. The sample consisted of 204 adolescents between the ages of 14 and 18 who answered a structured questionnaire (Ministry of Health / Ministry of Education) entitled: Do I need to be tested for HIV / AIDS? Results: The results identified that 62% of the male adolescents interviewed had already started the sexual practice while in the female gender it was 38%. There was considerable vulnerability among adolescents to HIV, 67.6% are vulnerable, and 82.9% of these adolescents are male. Conclusion: It is observed the need to intensify the attention to the health of the adolescents in the schools, offering to the young people information on the prevention of the aggravations related to the sexual activity


Objetivo: Conocer la vulnerabilidad de los adolescentes sobre el riesgo de contraer VIH / SIDA, vivida por los adolescentes de la escuela secundaria de una red pública en el municipio de Riachão do Dantas / SE. Métodos: Investigación transversal, de naturaleza cuantitativa. La muestra fue constituida por 204 adolescentes en el grupo de edad entre 14 y 18 años que respondieron un cuestionario estructurado (Ministerio de Salud / Ministerio de Educación) titulado: ¿Necesito hacer la prueba del VIH / SIDA? Resultados: Los resultados identificaron que el 62% de los adolescentes del género masculino entrevistados ya habían incitado la práctica sexual mientras que en el género femenino fue del 38%. Se observó una vulnerabilidad considerable entre los adolescentes al VIH, el 67,6% está en situación de vulnerabilidad, siendo que el 82,9% de estos adolescentes son del género masculino. Conclusión: Se observa la necesidad de intensificar la atención a la salud de los adolescentes en las escuelas, ofreciendo a los jóvenes información sobre la prevención de los agravios relativos a la actividad sexual


Assuntos
Humanos , Masculino , Feminino , Adolescente , Síndrome de Imunodeficiência Adquirida/prevenção & controle , HIV , Saúde do Adolescente , Prevenção Primária/educação , Promoção da Saúde
7.
RECIIS (Online) ; 13(2): 246-260, abr.-jun. 2019.
Artigo em Português | LILACS | ID: biblio-1005594

RESUMO

O objetivo deste artigo é destacar características e atravessamentos dos movimentos LGBTI brasileiros, da aids, do HIV e de coberturas jornalísticas da síndrome que surgiu publicamente no início dos anos 1980. Resgatamos dimensões históricas e questões atuais como desafiadoras para as ciências, a medicina, governos e militantes com o intuito de refletir sobre disputas que estiveram e estão em curso, principalmente aquelas que se relacionam com a LGBTIfobia e outras opressões sociais. A pesquisa foi realizada por meio de levantamento bibliográfico acerca das políticas do movimento LGBTI, do HIV e da aids, bem como do uso de resultados de pesquisa anteriormente realizada sobre homofobia e narrativas jornalísticas. Observou-se uma conexão complexa entre as relações engendradas no surgimento da síndrome, próxima aos primeiros passos do movimento LGBTI no Brasil, como a produção ambivalente de visibilidades, assim como a manutenção de preconceitos históricos que ainda reverberam no tecido social.


The aim of this article is to highlight the characteristics and crossings of Brazilian LGBTI, AIDS, HIV movements and of journalistic coverage of the syndrome that emerged publicly in the early 1980s. We brought up historical dimensions and current issues as challenging for the sciences, medicine, governments and militants in order to reflect on ongoing disputes, especially those that are related to LGBTIphobia and others social oppressions. The research was carried out through a bibliographical survey about policies of the LGBTI, HIV and AIDS movements, as well as the use of previously conducted research results on homophobia and journalistic narratives. It was observed a complex connection between the relations generated in the beginning of the syndrome, close to the first steps of the LGBTI movement in Brazil, as the ambivalent production of visibility, as well as the maintenance of historical prejudices that still reverberate in social world.


El objetivo de este artículo es subrayar puntos y atravesamientos de los movimientos LGBTI brasileños, del Sida, del VIH y de las coberturas periodísticas del síndrome que surgió en público en el principio de los años 1980. Rescatamos dimensiones históricas y cuestiones actuales desafiantes para las ciencias, la medicina, los gobiernos y militantes con el propósito de reflexionar sobre disputas que estuvieron y están en curso, principalmente aquellas que se relacionan con la LGBTIfobia y otras opresiones sociales. La investigación fue realizada por medio de levantamiento bibliográfico acerca de las políticas del movimiento LGBTI, del VIH y del Sida, así como del uso de resultados de investigación previamente realizada sobre homofobia y narrativas periodísticas. Se observó una conexión compleja entre las relaciones engendradas en el surgimiento del síndrome, próxima a los primeros pasos del movimiento LGBTI en Brasil, como la producción ambivalente de visibilidades, así como el mantenimiento de prejuicios históricos que aún reverberan en el tejido social.


Assuntos
Humanos , Brasil , Síndrome de Imunodeficiência Adquirida , HIV , Jornalismo , Minorias Sexuais e de Gênero , Doenças Virais Sexualmente Transmissíveis , Zidovudina , Síndrome de Imunodeficiência Adquirida/prevenção & controle , Cultura , Rede Social , Profilaxia Pré-Exposição , Opressão Social
8.
J Assoc Physicians India ; 67(4): 47-51, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31299839

RESUMO

Introduction: HIV Associated Neurocognitive Disorder (HAND) is still prevalent even in the ART (Anti-Retroviral Therapy) era. It may have some association with CD4 counts and Anti-Retroviral Therapy. The prevalence of HAND in HIV-patients, was, therefore studied in the context of ART and CD4 counts. Methods: Modified Mini Mental State Examination scores of 200 (65% males) HIV-positive patients and 200 controls were analyzed in the context of ART and CD4 counts. Results: Maximum number of participants were educated between 8th-12th class (89.5%), aged between 25-50 years (81.5%) and a higher proportion of males had a CD4 count <500 (69.2%) (p=0.007). Using 3MS, 21% patients (mean 76.24±1.51) and none of the controls were found to be neurocognitively impaired. Mean scores of patients with CD4 counts<500(82.54±5.58) were lesser in comparison to those of patients with CD4 counts>500 (p<0.001). Those with an ART duration of <48 months had a lower score in comparison to those with an ART duration of >72 months (p=0.005).Most decrease from maximum value was seen in similarities (48.3 %), second recall (36.1 %), repetition (33.4 %), copying two pentagons (28.3 %), read and obey (24.0 %), mental reversal (22.7 %) and first recall (21.3%) parameters of Modified Mini Mental State Examination. Conclusions: HAND was less prevalent in the present study in comparison to past literature. CD4 counts and ART duration had an inverse association with the degree of cognitive impairment. The parameters of Modified Mini Mental State Examination showing maximum impairment may be compiled to form a short screening questionnaire.


Assuntos
Infecções por HIV/epidemiologia , Transtornos Neurocognitivos/epidemiologia , Adulto , Idoso , Contagem de Linfócito CD4 , Feminino , HIV , Infecções por HIV/sangue , Infecções por HIV/terapia , Humanos , Índia/epidemiologia , Masculino , Testes de Estado Mental e Demência , Pessoa de Meia-Idade , Transtornos Neurocognitivos/sangue , Transtornos Neurocognitivos/tratamento farmacológico , Prevalência
9.
J Assoc Physicians India ; 67(3): 42-45, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31304705

RESUMO

Objectives: The main aim of this study was to assess vitamin D [25(OH)D]levels in an HIV infected adult population and to define HIV and antiretroviral-related factors associated with vitamin D deficiency. Methods: This observational analytical study was conducted on 475 adult patients on follow up at Apex Immunodeficiency Center of Base Hospital, Delhi Cantt. We estimated the prevalence of vitamin D insufficiency/deficiency(<30 ng/ml). Age, gender, BMI, CD4 count, plasma viral load, HBV/HCV coinfection, smoking status, time since diagnosis of HIV infection and selected liver enzymes were recorded. Antiretroviral therapy regimen was taken into account and its relationship with vitamin D levels were noted. Results: Vitamin D insufficiency/deficiency was noted in 92.63% of patients out of which 65.68 % were males. Median age of vitamin D sufficient group was slightly higher(52.11 vs 49.95). Patients with higher body mass index (BMI) had a slightly higher rates of Vitamin D insufficiency(24.2 vs 22.3). More the time interval from the date of diagnosis higher were the chances of deficiency/insufficiency. Co-infected patients with hepatitis B and C had sufficient vitamin D levels in 71.92% patients. Efavirenz(66.93%), nevirapine(79.02%), tenofovir(64.84%) and ritonavir(84.90%) containing regimens had consistently low levels of vitamin D. Abnormal liver enzymes viz alanine aminotransferase, alkaline phosphatase and gamma glutamyl transferase were associated with higher rates of deficient vitamin D levels. Conclusions: Vitamin D deficiency is very high in HIV patients on antiretroviral therapy. . Efavirenz (EFV), Nevirapine (NVP), Tenofovir (TDF) and Protease Inhibitors (PI's) were associated with high levels of deficiency/insufficiency of vitamin D levels. Vitamin D supplementation as a global strategy in all HIV positive patients on antiretroviral therapy is advocated.


Assuntos
Infecções por HIV/epidemiologia , Deficiência de Vitamina D/epidemiologia , Adulto , HIV , Humanos , Índia/epidemiologia , Masculino , Prevalência , Vitamina D
10.
J Assoc Physicians India ; 67(3): 67-70, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31304710

RESUMO

Background: Alanine aminotransferase (ALT) is commonly used to measure liver injury in resource limited settings. Elevations in ALT are predictive of increased mortality from liver disease and may be influenced by antiretroviral drugs and concomitant hepatitis B infection. Methods: A cross-sectional analysis of the prevalence and predictors of elevated ALT (defined as> 40 IU/L) on HIV patients on antiretroviral therapy (ART) was conducted. Baseline ALT levels and at two weeks, six weeks, twelve weeks, twenty four weeks and one year were recorded for 320 patients on ART. Hepatitis B surface antigen was also recorded at baseline. Results: Out of the total 320 patients, 249 were males and 71 females. A total of 252 patient records were used as controls who were not on ART. The mean ALT record before initiating ART was 30.6 IU/L. Peak rise in ALT was observed at twenty four weeks of therapy with mean ALT levels of 54.42 IU/L. Total toxicity was almost similar between the two regimes, nevirapine based being 17.62% and efavirenz based being 16.16%.Toxicty grades were lesser in Hepatitis B positive patients as compared with hepatitis B negative patients overall. Conclusions: This study concludes that elevated ALT levels are seen in patients on antiretroviral therapy and persist throughout the course of first year, though maximum levels are seen at around twenty four weeks of therapy. Total hepatotoxicity was found to be 16.89%. Longer follow up of patients is required to assess the effect of ALT elevations on morbidity and mortality of patients and a close monitoring of ALT is required in patients on ART and other hepatotoxic therapies.


Assuntos
Alanina Transaminase/metabolismo , Antirretrovirais/uso terapêutico , Infecções por HIV/metabolismo , Estudos Transversais , Feminino , HIV , Infecções por HIV/tratamento farmacológico , Infecções por HIV/epidemiologia , Humanos , Índia , Masculino
13.
Zhonghua Liu Xing Bing Xue Za Zhi ; 40(6): 638-642, 2019 Jun 10.
Artigo em Chinês | MEDLINE | ID: mdl-31238611

RESUMO

Objective: To explore the survival status and influencing factors on former plasma donors (FPD) living with HIV/AIDS after initiation of antiretroviral therapy (ART) during 2002-2017 in Henan province. Methods: A retrospective study was conducted, using data from the ART database of national comprehensive HIV/AIDS information system. The inclusion criteria on patients would include HIV/AIDS cases with current residence in Henan province, route of infection being blood-borne (plasma collection), initiation of ART between 2002 and 2017, and 15 year-olds or above. According to the time of initation on antiviral treatment, observation was carried on between January 1, 2002 and December 31, 2017. Outcome of observation was defined as death caused by AIDS or related diseases. Life Table was used to estimate the survival rate and Kaplan-Meier method was used to draw the survival curve. Log-rank test was used to compare the univariate intergroup survival rates while Cox proportional hazards regression model was used to analyze the influencing factors on survival status among deaths due to AIDS or related diseases. Excel 2010 software and SPSS 23.0 software was used for data cleaning and statistical analysis. Results: A total of 25 825 HIV/AIDS patients were enrolled in this study. During the follow-up period, the overall mortality was 3.9/100 person year (8 354/214 796.3), among all the patients. The accumulate survival rates of 1 year, 4 years, 8 years, 12 years and 16 years after the initiation of ART were 91.2%, 80.1%, 71.2%, 65.7% and 61.5%, respectively. The results from the multivariate Cox proportional hazards regression model analysis showed that male vs. female (aHR=1.46, 95%CI: 1.39-1.53); aged 45-49 years group and aged 60 and older years group of initiating ART vs. aged 15-44 years group of initiating ART respectively (aHR=1.47, 95%CI: 1.40-1.54; aHR=2.50, 95%CI: 2.22-2.81); other marital status vs. being married or under cohabitation (aHR=1.29, 95%CI: 1.21-1.36); baseline CD(4)(+)T cells counts (CD(4))<50, 50-199 and 200-349 cells/µl respectively vs. baseline CD(4)≥350 cells/µl (aHR=4.50, 95%CI: 4.14- 4.89; aHR=2.49, 95%CI: 2.31-2.69; aHR=1.44, 95%CI: 1.33-1.56); number of opportunistic infections at baseline were one case, 2-3 cases and 4-5 cases respectively vs. non opportunistic infections cases at baseline (aHR=1.17, 95%CI: 1.06-1.29; aHR=1.47, 95%CI: 1.35-1.59; aHR=1.74, 95%CI: 1.60-1.89); taking TMP-SMZ vs. not taking TMP-SMZ (aHR=0.69, 95%CI: 0.65- 0.73). Conclusions: The 16-year accumulate survival rate was 61.5% among FPD living with HIV/AIDS after initiation of ART, during 2002 to 2017 in Henan province. The risk factors for FPD death case would include: being males, aged 45 and older years at the initiation of ART, baseline CD(4)<350 cells/µl and the number of baseline opportunistic infections cases ≥1. The protective factors on FPD death appeared as: being married or cohabited as wel as on TMP-SMZ.


Assuntos
Doadores de Sangue , Infecções por HIV/tratamento farmacológico , Infecções por HIV/mortalidade , Doadores Vivos , Adulto , Idoso , Feminino , HIV , Infecções por HIV/sangue , Humanos , Masculino , Pessoa de Meia-Idade , Modelos de Riscos Proporcionais , Estudos Retrospectivos , Análise de Sobrevida , Taxa de Sobrevida
14.
Zhonghua Liu Xing Bing Xue Za Zhi ; 40(6): 654-659, 2019 Jun 10.
Artigo em Chinês | MEDLINE | ID: mdl-31238614

RESUMO

Objective: To study the prevalence and correlates of diabetes among HIV/AIDS who were on antiretroviral therapy (ART) in Dehong Dai and Jingpo autonomous prefectures (Dehong), Yunnan province. Methods: The database of HIV/AIDS receiving ART in Dehong was downloaded by using the basic information system of AIDS prevention and control in China. In this cross-sectional study, HIV/AIDS patients who were currently on ART and aged 18 years or above, were consecutively recruited, between July 2017 and June 2018, in Dehong. All the subjects underwent hemoglobin A1c (HbA1c) testing. Patient with diabetes was defined as meeting any of these indicators (HbA1c ≥6.5%, baseline FPG ≥7.0 mmol/L, FPG ≥7.0 mmol/L in the most recent visit). Both univariate and multivariate logistic regression analysis were carried on to evaluate the correlates of diabetes among the HIV/AIDS patients. Results: In total of 4 376 HIV/AIDS patients were included for analysis, with the average age as (43.7±10.1) years, proportion of males as 53.8% (2 356/4 376) and the HCV positive rate as 24.1% (1 055/4 376). The mean years was (8.9±3.8) years after the HIV diagnosis was made, and the mean duration on treatment was (6.8±2.9) years. The prevalence of diabetes was 11.4% (500/4 376). Through multivariate logistic regression analysis, data showed that the risk factors of diabetes of HIV/AIDS on ART were: aged 40 years or above, being male, HCV positive, baseline body mass index ≥24.0 kg/m(2), elevated TG ≥1.70 mmol/L in the most recent visit and baseline antiretroviral regimens under Efavirenz (EFV). Conclusions: Prevalence rate of diabetes appeared higher in HIV/AIDS patients who were on ART in Dehong. Prevention and control measures should be targeted on HIV/AIDS patients who were with risk factors of diabetes as being elderly, male, HCV positive, overweight and higher TG. Further esearch is needed to evaluate the association between the use of EFV and diabetes.


Assuntos
Terapia Antirretroviral de Alta Atividade , Diabetes Mellitus/epidemiologia , Infecções por HIV/tratamento farmacológico , Adolescente , Adulto , Idoso , China/epidemiologia , Estudos Transversais , Complicações do Diabetes/epidemiologia , HIV , Infecções por HIV/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência
17.
BMC Public Health ; 19(1): 731, 2019 Jun 11.
Artigo em Inglês | MEDLINE | ID: mdl-31185962

RESUMO

BACKGROUND: With Universal Health Coverage and Integrated People-centred Health Care, streamlined health-systems and respectful care are necessary. South Africa has made great strides in prevention of mother-to-child transmission (PMTCT) but with the great burden of HIV, a minimum of birth and 10-week HIV-PCR testing are required for the estimated 360,000 HIV-exposed infants born annually which presents many challenges including delayed results and loss to follow-up. Point-of-care (POC) HIV testing of infants addresses these challenges well and facilitates initiation of HIV-infected infants rapidly after diagnosis for best clinical outcomes. METHODS: Objectives were to determine accuracy, feasibility and acceptability of POC testing compared to standard-of-care (SOC) central-laboratory testing. HIV-exposed infants for birth PCR testing in hospital (n = 323) and follow-up at a primary health care clinic (n = 117) in Durban, South Africa were included. A baseline situational-analysis reviewed registers and phoned mothers of HIV-exposed infants prior to the intervention. An effectiveness-implementation study of the Alere™q HIV-1/2 Detect POC test (heel-prick specimen processed in 50 min) was compared with SOC with questionnaires to mothers and staff. Stata 14 was used for analysis. RESULTS: At baseline 2% of birth HIV tests were missed; only 40% of mothers could be contacted; 17% did not receive birth test result; 19% did not have a 10-week test; 39% had not received the 10-week results. There were 5(1.5%) HIV-infected and 318(98.5%) HIV-negative infants detected in hospital with all clinic babies negative. All positive infants commenced ART before discharge. Ultimately POC and SOC had perfect concordance but for 10 SOC tests researchers actively tracked-down results or repeated tests. Turn around times for SOC tests were on average 8-days (IQR 6-10 days) and for POC testing was 0-days. The POC error-rate was 9,6% with all giving a result when repeated. The majority of mothers (92%) preferred POC testing with 7% having no preference. No staff preferred SOC testing with 79% preferring POC and 21% having no preference. CONCLUSIONS: Point-of-care HIV testing for EID is accurate, feasible and acceptable, with benefits of early ART for all positive infants at birth facilities. We recommend that it be considered best practice for EID. TRIAL REGISTRATION: ISRCTN38911104 registered 9 January 2018 - retrospectively registered.


Assuntos
Infecções por HIV/diagnóstico , HIV , Implementação de Plano de Saúde , Triagem Neonatal/métodos , Sistemas Automatizados de Assistência Junto ao Leito , Diagnóstico Precoce , Feminino , Infecções por HIV/prevenção & controle , Infecções por HIV/transmissão , Humanos , Recém-Nascido , Transmissão Vertical de Doença Infecciosa/prevenção & controle , Masculino , Reação em Cadeia da Polimerase/métodos , Gravidez , Estudos Retrospectivos , África do Sul
19.
Stud Health Technol Inform ; 261: 299-302, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31156134

RESUMO

BACKGROUND: after the discovery of the antiretroviral therapy, life expectancy of HIV+ patient has become longer and this meant that he would start ageing. International literature demonstrated that the HIV+ patient is more fragile than any other person of the same age and that doesn't present the viral infection. OBJECTIVE: design, development and test of a new web-based instrument to allow the self-administration of the new questionnaire SELFY MPI created during the European project Effichronic. Materials & Methods: between June and September 2018, a group of senior 50 HIV+ patients, was involved. The questionnaire SELFY MPI enables to collect data about quality of life and cognitive functions. RESULTS: the developed web-instrument collects pseudo-anonymous data into the Liguria HIV Network database. The subsequent statistical analysis highlighted a correlation between the two outcomes of SELFY MPI and the laboratory exam's parameter TCD4+ and viral load. CONCLUSIONS: the great potentiality of this instrument is not only the support given to clinical research about the effects of HIV on chronical disease management but it can be also used as a follow-up instrument to evaluate different aspects of the geriatric patient life during the years.


Assuntos
Fragilidade , Infecções por HIV , Internet , Dados de Saúde Gerados pelo Paciente , Qualidade de Vida , Idoso , Idoso Fragilizado , HIV , Infecções por HIV/complicações , Humanos , Masculino , Inquéritos e Questionários
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