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1.
Arq. bras. med. vet. zootec. (Online) ; 71(6): 1835-1838, Nov.-Dec. 2019.
Artigo em Português | LILACS, VETINDEX | ID: biblio-1055119

RESUMO

As hemorragias podem levar à morte, em caso de não interrupção e recuperação da volemia. A substituição do sangue pode ser realizada por transfusão homóloga ou autóloga. Na transfusão homóloga, o sangue é obtido de um doador, na autotransfusão ou transfusão autóloga, o sangue é coletado do próprio paciente. Objetivou-se relatar a autotransfusão em um cão como um método simples, rápido e barato, e discutir esse procedimento como uma alternativa emergencial para clínicas e hospitais que não possuem bancos de sangue ou animais doadores. Foi atendido um cão Rottweiler fêmea, 42,8kg, 10 anos de idade, com queixa principal de tumor mamário e para realização de castração. Após o procedimento, a paciente apresentou hemoperitônio, sendo encaminhada para novo procedimento cirúrgico, durante o qual se observou grande quantidade de sangue livre na cavidade abdominal. Foi realizada a autotransfusão de emergência, pela técnica das duas seringas, devido à indi1111sponibilidade de sangue ou animal doador no momento do procedimento cirúrgico emergencial, demonstrando ser uma opção eficiente, econômica, de fácil acesso e segura, por ser uma transfusão normotérmica, apresentar diminuição do risco de sobrecarga circulatória e por ser o sangue compatível, devendo ser mais explorada, pois existem poucos dados descritos na literatura.(AU)


Hemorrhages can lead to death in case of non-interruption and recovery of blood volume. Blood replacement may be performed by homologous or autologous transfusion. In homologous transfusion, blood is obtained from a donor, in autotransfusion or autologous transfusion, blood is collected from the patient himself. We aimed to report autotransfusion in a dog as a simple, quick, and inexpensive method, and discuss it as an emergency alternative for clinics and hospitals that do not have blood banks or animal donors. A female Rottweiler dog, 42.8kg, 10 years of age, was treated with a primary complaint of mammary tumor and for castration. After the procedure the patient presented hemoperitoneum, being referred to a new surgical procedure, where a large amount of free blood was observed in the abdominal cavity. The emergency autotransfusion was performed by the two syringes technique, due to the unavailability of blood or donor animal at the time of the emergency surgical procedure, proving to be an efficient, economical, easily accessible and safe option because it is a normothermic transfusion, risk of circulatory overload and blood is compatible. It should be more exploited because there are few data described in the literature.(AU)


Assuntos
Animais , Cães , Transfusão de Sangue Autóloga/veterinária , Hemoperitônio/veterinária , Hemorragia/veterinária
2.
J Vet Emerg Crit Care (San Antonio) ; 29(5): 535-541, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31423720

RESUMO

OBJECTIVE: To describe the technique and outcome of temporary abdominal packing for control of persistent hemorrhage from liver lobectomy sites in 3 dogs with hepatic neoplasia. SERIES SUMMARY: Three dogs were treated with massive transfusion for hemoperitoneum secondary to bleeding hepatic tumors. Surgical resection of the affected liver lobe(s) was performed but hemostasis could not be achieved through conventional methods. All 3 dogs demonstrated acidosis, hypothermia, and coagulopathy. Temporary abdominal packing of liver lobectomy sites was performed and hemostasis was achieved in all dogs. One dog died prior to removal of the packing. The other 2 dogs had the packing removed with no evidence of rebleeding. One dog was euthanized after removal of the packing due to acute kidney injury and the remaining dog survived to discharge. NEW OR UNIQUE INFORMATION PROVIDED: Temporary abdominal packing combined with medical management was successful in achieving hemostasis in all 3 dogs, however, 2 dogs died of complications related to multiple organ dysfunction syndrome. Temporary abdominal packing may be considered when definitive surgical hemostasis cannot be achieved or in unstable patients not able to tolerate prolonged surgical times. Further research is needed to better define efficacy, optimal patient selection, packing technique, timing of removal, and complications associated with temporary abdominal packing.


Assuntos
Doenças do Cão/cirurgia , Hemoperitônio/veterinária , Técnicas Hemostáticas/veterinária , Neoplasias Hepáticas/veterinária , Hemorragia Pós-Operatória/veterinária , Animais , Cães , Feminino , Hemoperitônio/terapia , Neoplasias Hepáticas/cirurgia , Masculino , Hemorragia Pós-Operatória/terapia
3.
J Vet Emerg Crit Care (San Antonio) ; 29(3): 239-245, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30994972

RESUMO

OBJECTIVE: To calculate a risk prediction model for hemangiosarcoma (HSA) diagnosis in dogs presenting with nontraumatic hemoabdomen. DESIGN: Retrospective multicenter observational cohort study enrolling dogs presented 2003-2016. SETTING: Five academic veterinary medical centers. ANIMALS: A total of 406 dogs with nontraumatic hemoabdomen as the presenting complaint that underwent surgical exploration or necropsy and received a histological diagnosis. Overall, 219 dogs from 3 centers provided the data for model construction, and 187 dogs from 2 centers provided the population for external validation. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The risk score was modeled on 4 predictors: bodyweight (P = 0.01), total plasma protein (P < 0.01), platelet count (P < 0.01), and thoracic radiograph findings (P = 0.02). The incidence of HSA diagnosis was 36%, 76%, and 96% in the low risk (≤40), medium risk (41-55), and high risk (>55) score groups, respectively. The risk score AUROC was 0.85 (95% CI 0.79-0.90) on the construction population, and 0.77 (95% CI 0.70-0.84) on the validation population. CONCLUSIONS: The risk of HSA diagnosis in dogs presenting with nontraumatic hemoabdomen could be predicted using a simple risk score, which could aid in identification and treatment of dogs at lower risk for this diagnosis.


Assuntos
Neoplasias Abdominais/veterinária , Doenças do Cão/diagnóstico , Hemangiossarcoma/veterinária , Índice de Gravidade de Doença , Neoplasias Abdominais/complicações , Neoplasias Abdominais/diagnóstico , Animais , Estudos de Coortes , Doenças do Cão/sangue , Cães , Feminino , Hemangiossarcoma/complicações , Hemangiossarcoma/diagnóstico , Hemoperitônio/etiologia , Hemoperitônio/veterinária , Masculino , Ontário , Reprodutibilidade dos Testes , Estudos Retrospectivos , Fatores de Risco , Estados Unidos
5.
Vet Surg ; 47(8): 1031-1038, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30246401

RESUMO

OBJECTIVE: To compare anatomic sources and underlying etiology of hemorrhage in small vs large dogs with spontaneous hemoperitoneum (SH). STUDY DESIGN: Retrospective cross-sectional study. ANIMALS: Client-owned dogs with SH at 2 academic institutions. METHODS: Medical records were reviewed for age, breed, sex, weight, and results of imaging, surgery, necropsy, cytology, and histopathology. Dogs were divided according to body weight (≤ 20 kg = small, > 20 kg = large). Confidence intervals were calculated to estimate rates of splenic and hepatic hemorrhage in small and large dog SH populations. Multivariable regression was used to compare prevalence of anatomic sources of hemorrhage and etiology in small vs large dogs. RESULTS: We identified 742 dogs with SH, including 637 in which the anatomic site of hemorrhage was investigated. Splenic hemorrhage was diagnosed in 43.2% (95% CI, 34.3-52.4) of small dogs and 61.3% (95% CI, 57.0-65.6) of large dogs. Small dogs had lower prevalence of splenic hemorrhage (prevalence ratio, 0.70; 95% CI, 0.58-0.87; P < .001) and higher prevalence of hemorrhage from liver (prevalence ratio, 1.72; 95% CI, 1.20-2.47; P = .003) or from another location such as retroperitoneal mass, kidney, or adrenal (prevalence ratio, 2.73; 95% CI, 1.66-4.47; P < .001) vs large dogs. Hemangiosarcoma was associated with splenic hemorrhage and occurred more frequently in large vs small dogs (P = .011). CONCLUSION: Small dogs had a lower rate of splenic hemorrhage and higher rates of hemorrhage from liver and other sites compared to large dogs. Etiologies other than splenic hemangiosarcoma were common, particularly among dogs weighing ≤ 20 kg. CLINICAL SIGNIFICANCE: Clinicians should perform diagnostics and consider body size before making presumptive diagnoses in dogs with SH.


Assuntos
Doenças do Cão/epidemiologia , Hemoperitônio/veterinária , Registros , Esplenopatias/veterinária , Medicina Veterinária , Animais , California/epidemiologia , Estudos Transversais , Doenças do Cão/etiologia , Doenças do Cão/patologia , Cães , Feminino , Hemoperitônio/epidemiologia , Masculino , Prevalência , Estudos Retrospectivos , Esplenopatias/epidemiologia
6.
Vet Surg ; 47(8): 1039-1045, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30242852

RESUMO

OBJECTIVE: To determine the influence of administering allogeneic blood products (ABP) on the progression of hemangiosarcoma in dogs. STUDY DESIGN: Multi-institutional, retrospective study. SAMPLE POPULATION: One hundred four dogs with hemangiosarcoma that survived until postoperative discharge from the hospital. METHODS: Medical records of dogs that had been operated on for hemoangiosarcoma were reviewed for signalment, presence of a hemoabdomen, presence of metastatic disease, and whether the dog had received chemotherapy or Yunnan Baiyao. Data that were collected were compared between dogs that received perioperative ABP and those that did not. Disease-free interval was compared between groups. The Kaplan-Meier method was used to obtain univariate descriptive statistics for time to clinical decline. A multivariable Cox regression model was used to analyze association or effect of potential predictor variables. RESULTS: The median disease-free interval (DFI) was shorter in the 67 dogs that received a blood transfusion (76 days; range, 1-836) than in the 37 dogs that did not receive a blood transfusion (120 days; range, 38-916). According to the multivariable Cox regression model, administration of blood products (P = .04) and the presence of gross metastatic disease at the time of surgery (P < .01) shortened the DFI, whereas administration of Yunnan Baiyao (P = .01) prolonged the DFI. CONCLUSION: Allogeneic blood product administration was associated with a shorter disease-free interval in this population. However, we could not demonstrate the association between blood products and shorter DFI because of confounding factors. CLINICAL SIGNIFICANCE: Dogs that receive ABP at the time of surgical therapy for hemangiosarcoma may have accelerated disease progression compared with dogs that do not receive ABP.


Assuntos
Transfusão de Sangue/veterinária , Doenças do Cão/cirurgia , Hemangiossarcoma/veterinária , Hemoperitônio/veterinária , Neoplasias Esplênicas/veterinária , Animais , China , Doenças do Cão/mortalidade , Cães , Feminino , Hemangiossarcoma/cirurgia , Hemoperitônio/cirurgia , Masculino , Complicações Pós-Operatórias/mortalidade , Estudos Retrospectivos , Neoplasias Esplênicas/cirurgia , Análise de Sobrevida
7.
J Vet Emerg Crit Care (San Antonio) ; 28(5): 476-482, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30102015

RESUMO

OBJECTIVE: To describe the clinical presentation of a dog with spontaneous hemoperitoneum associated with anaphylactic shock from Hymenoptera envenomation. CASE SUMMARY: An 8-year-old female neutered Beagle presented as an emergency for acute onset of collapse, hematemesis, and hematochezia. The dog was tachycardic, tachypneic, and hypotensive. Initial assessment revealed a hemoperitoneum with documentation of a nonclotting sanguineous peritoneal effusion with PCV 81% and total protein concentration 65 g/L (6.5 g/dL). No obvious masses were appreciated ultrasonographically during original presentation and cytology of the peritoneal effusion was unremarkable. Peripheral PCV was 67% and total plasma protein concentration was 72 g/L (7.2 g/dL). A bee stinger was located in the right upper lip after presentation and was postulated to be the inciting trigger for the abdominal hemorrhage and shock. The patient was medically stabilized and ultimately made an uneventful recovery. Abdominal ultrasound performed 3 days after discharge revealed a single 0.85 cm hyperechoic liver nodule. Follow-up evaluation at 6 and 18 months after presentation documented a normal physical examination, unremarkable thoracic radiographs, and no change in the original hyperechoic liver nodule. NEW OR UNIQUE INFORMATION PROVIDED: This report details an unusual clinical presentation of anaphylactic shock due to Hymenoptera envenomation in a dog. To the authors' knowledge, spontaneous hemoperitoneum associated with anaphylaxis and bee envenomation has not been documented in the veterinary literature.


Assuntos
Anafilaxia/veterinária , Doenças do Cão/diagnóstico , Hemoperitônio/veterinária , Himenópteros , Mordeduras e Picadas de Insetos/veterinária , Anafilaxia/complicações , Anafilaxia/diagnóstico , Animais , Diagnóstico Diferencial , Cães , Feminino , Hemoperitônio/induzido quimicamente , Hemoperitônio/complicações , Mordeduras e Picadas de Insetos/complicações , Mordeduras e Picadas de Insetos/diagnóstico
8.
Artigo em Alemão | MEDLINE | ID: mdl-29898480

RESUMO

A 2-year-old Bearded Collie was referred for suspected hemoabdomen after prescrotal castration. On presentation the dog was in stable body condition and the hematocrit was within the reference range. Abdominal ultrasound revealed a moderate amount of free corpuscular fluid; therefore the dog was prepared for laparoscopic surgery. A single port access at the umbilicus was performed and insufflation with CO2 started with a pressure of 8 mmHg. Approximately one liter of blood was removed from the abdominal cavity with a suction/irrigation tube to allow inspection of the inguinal rings. The laparoscopic approach allowed excellent visualization of the spermatic cord and testicular vessels, which were then sealed with a vessel-sealing device. After surgery, the dog recovered well and did not develop further complications. This case report shows that laparoscopy is feasible in the event of hemoabdomen after castration in dogs and can be considered as an alternative treatment method in the hands of a surgeon, well experienced in minimally invasive surgery. The experience of this case report raises the question, if hemoabdomen should be no longer considered as an absolute contraindication for laparoscopy and should be considered as a relative contraindication instead.


Assuntos
Cães/cirurgia , Hemoperitônio/veterinária , Laparoscopia/veterinária , Orquiectomia/efeitos adversos , Orquiectomia/veterinária , Animais , Hemoperitônio/etiologia , Hemoperitônio/cirurgia , Laparoscopia/efeitos adversos , Laparoscopia/métodos , Masculino
9.
Schweiz Arch Tierheilkd ; 160(5): 305-312, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29717984

RESUMO

INTRODUCTION: Tranexamic acid (TXA) is an antifibrinolytic drug that is used for uncontrolled bleeding of various origin. This retrospective study investigated the effect of tranexamic acid administration on bleeding tendency in dogs with surgically managed hemoperitoneum. Thirty dogs were treated with (TXA group) and 25 dogs without (CTR group) tranexamic acid prior to surgery. Various parameters (decrease in haematocrit, number of transfusions, shock index and changes in abdominal fluid accumulation) were used for characterization of bleeding tendency and compared between groups. Groups were similar at presentation and prior to surgery. None of the dogs undergoing rotational thromboelastography analysis showed hyperfibrinolysis prior to surgery. Overall transfusion and erythrocyte transfusion requirements as well as bleeding tendency, hospitalisation time and hospital discharge rate were similar between groups. Dogs of the TXA group received significantly more intraoperative plasma transfusions (P=0.013) and showed a higher systolic and mean arterial blood pressure (P=0.002 and 0.050) and lower shock index (P=0.028) with less dogs being in shock (P=0.012) at 24h. In summary, in this study population of dogs with surgically managed spontaneous hemoperitoneum dogs treated with tranexamic acid received more plasma transfusions intraoperatively and showed a lower shock index 24h after presentation. In dogs with surgically treated hemoabdomen tranexamic acid administration prior to surgery does not reduce red blood cell transfusion requirements or postoperative bleeding tendency.


Assuntos
Doenças do Cão/tratamento farmacológico , Doenças do Cão/cirurgia , Hemoperitônio/veterinária , Hemorragia Pós-Operatória/veterinária , Ácido Tranexâmico/farmacologia , Animais , Antifibrinolíticos/farmacologia , Pressão Sanguínea/efeitos dos fármacos , Cães , Hemoperitônio/tratamento farmacológico , Hemoperitônio/cirurgia , Hemorragia Pós-Operatória/tratamento farmacológico , Estudos Retrospectivos
10.
Can Vet J ; 57(8): 865-8, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27493287

RESUMO

A juvenile Chihuahua dog developed hemoperitoneum after routine ovariohysterectomy. She was managed with packed red blood cell and fresh frozen plasma transfusions as well as an exploratory laparotomy to verify ligature sites. No recurrence of hemorrhage occurred. Factor X deficiency was diagnosed and confirmed with repeat analysis including during times of health.


Assuntos
Doenças do Cão/etiologia , Deficiência do Fator X/veterinária , Animais , Cães , Deficiência do Fator X/etiologia , Feminino , Hemoperitônio/veterinária , Histerectomia/veterinária , Ovariectomia/veterinária , Complicações Pós-Operatórias/veterinária
11.
J Vet Emerg Crit Care (San Antonio) ; 26(6): 766-774, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27074590

RESUMO

OBJECTIVE: To describe the successful use of an autotransfusion technique utilizing 2 syringes in 4 dogs. CASE SERIES SUMMARY: All 4 dogs in this series had a hemoabdomen and subsequent hypovolemic shock. During surgery blood was collected from the abdominal cavity by the surgeon and passed to an assistant. The blood was then transferred to a second syringe for direct IV administration. The blood was passed through an inline blood filter prior to reaching the patient. Given the transfusion volume and administration time frame, 3 cases were classified as a massive transfusion. All 4 dogs survived the transfusion, were discharged within 3 days of surgery/transfusion and no complications were noted. NEW OR UNIQUE INFORMATION PROVIDED: This case series describes a relatively simple method of performing an autotransfuion in patients with hemoabdomen and hypovolemic shock.


Assuntos
Transfusão de Sangue Autóloga/veterinária , Doenças do Cão/terapia , Hemoperitônio/veterinária , Hemorragia Pós-Operatória/veterinária , Animais , Transfusão de Sangue Autóloga/instrumentação , Cães , Feminino , Hemoperitônio/terapia , Histerectomia/veterinária , Masculino , Ovariectomia/veterinária , Hemorragia Pós-Operatória/terapia , Seringas/veterinária
12.
J Vet Emerg Crit Care (San Antonio) ; 26(6): 851-857, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27074964

RESUMO

OBJECTIVE: To describe a case of hemoperitonium in a dog with Bartonellosis and peliosis hepatis (PH) lesions that resolved following antimicrobial therapy. CASE SUMMARY: A 3-year-11-month-old 22.5 kg female spayed mixed breed dog presented for progressive lethargy and vomiting. An abdominal ultrasonographic examination revealed moderate ascites, which when sampled was nonclotting hemorrhagic fluid. An exploratory laparotomy revealed a large volume of nonclotted blood in the dog's abdomen and blood-filled vesicular lesions dispersed diffusely along multiple lobes of the liver. Biopsies revealed lesions indicative of PH. Serology testing for Bartonella species was positive. Treatment with azithromycin resulted in Bartonella serology negative status and no further evidence of hemoperitonium at recheck examination 12 months after initial presentation. NEW OR UNIQUE INFORMATION PROVIDED: This is the first reported case of PH and hemoperitoneum in a Bartonella species serology positive dog wherein treatment with azithromycin resulted in serology negative status. There have been no subsequent episodes of hemoperitoneum in the 12 months since treatment.


Assuntos
Antibacterianos/uso terapêutico , Azitromicina/uso terapêutico , Infecções por Bartonella/veterinária , Doenças do Cão/diagnóstico , Hemoperitônio/veterinária , Peliose Hepática/veterinária , Animais , Antibacterianos/administração & dosagem , Azitromicina/administração & dosagem , Infecções por Bartonella/diagnóstico , Diagnóstico Diferencial , Doenças do Cão/tratamento farmacológico , Doenças do Cão/cirurgia , Cães , Feminino , Hemoperitônio/diagnóstico , Peliose Hepática/diagnóstico
13.
Artigo em Inglês | MEDLINE | ID: mdl-26220266

RESUMO

OBJECTIVE: To relate coagulation and fibrinolysis derangements to shock severity as reflected by plasma lactate concentrations in dogs with spontaneous hemoperitoneum (SHP) and determine the impact on transfusions. DESIGN: Prospective, observational, case-control study. SETTING: Three veterinary teaching hospitals. ANIMALS: Twenty-eight client-owned dogs with SHP and 28 breed- and age-matched control dogs. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Blood samples for platelet counts, coagulation, and anticoagulant assays (prothrombin time, activated partial thromboplastin time, fibrinogen, antithrombin, and protein C, thromboelastography [TEG]), fibrinolysis testing (d-dimer and TEG lysis parameters with and without the addition of 50 U/mL of tissue plasminogen activator [TEG LY30 measured with the addition of 50 U/mL of tPA to the blood sample, LY3050 and TEG LY60 measured with the addition of 50 U/mL of tPA to the blood sample, LY6050 ; LY30 and LY60]), and plasma lactate as an indicator of severity of shock were collected from SHP dogs at the time of diagnosis. SHP dogs were hypocoagulable (prolonged prothrombin time and activated partial thromboplastin time, decreased TEG maximum amplitude) and hyperfibrinolytic (increased LY3050 and TEG LY6050 ) compared to controls. The severity of hypocoagulability was related to protein C activity, while the severity of hyperfibrinolysis was related to plasma lactate concentration. Among the 18 dogs discharged from the hospital, LY3050 was significantly associated with the dose of fresh frozen plasma administered, but none of the parameters were associated with the dose of red blood cells administered. CONCLUSIONS: Dogs with SHP have evidence of hypocoagulability, protein C deficiency, and hyperfibrinolysis. Parameters of hyperfibrinolysis were related to plasma lactate concentrations and volume of plasma transfused during hospitalization. These derangements resemble those found in people with acute coagulopathy of trauma and shock, and activation of protein C may be a common feature to both syndromes.


Assuntos
Transtornos da Coagulação Sanguínea/veterinária , Doenças do Cão/patologia , Hemoperitônio/veterinária , Ácido Láctico/sangue , Proteína C/metabolismo , Animais , Estudos de Casos e Controles , Doenças do Cão/sangue , Doenças do Cão/metabolismo , Cães , Produtos de Degradação da Fibrina e do Fibrinogênio , Fibrinogênio , Hemoperitônio/sangue , Hemoperitônio/metabolismo , Tempo de Tromboplastina Parcial , Estudos Prospectivos , Tempo de Protrombina/veterinária , Choque/veterinária , Tromboelastografia/veterinária
14.
Vet Comp Oncol ; 14(3): 295-305, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25041357

RESUMO

25-hydroxyvitamin D (25(OH)D) is important in bone health as well as many diseases including cancer. Supplementation may increase responsiveness of cancer cells to chemotherapy. Serum 25(OH)D, intact parathyroid hormone (iPTH) and canine C-reactive protein (c-CRP) were measured in healthy dogs and dogs with haemoabdomen. Regression analysis determined optimal 25(OH)D concentrations. In healthy dogs (n = 282), mean iPTH concentrations correlated inversely (r(2) = 0.88, P < 0.001) to 25(OH)D concentrations. Variation in both iPTH and c-CRP plateaued at 25(OH)D concentrations of 100-120 ng mL(-1) . Haemoabdomen dogs (n = 63, 43 malignant and 20 benign) had 25(OH)D concentrations ranging from 19.4 to >150 ng mL(-1) . Relative risk of cancer increased with decreasing 25(OH)D concentrations [RR = 3.9 for 25(OH)D below 40 ng mL(-1) (P = 0.0001)]. Serum 25(OH)D concentrations in dogs vary widely, and are influenced by dietary VitD content. Serum vitD measurement can identify dogs for which supplementation may improve health and response to cancer therapy.


Assuntos
Doenças do Cão/etiologia , Hemoperitônio/veterinária , Neoplasias/veterinária , Vitamina D/análogos & derivados , Animais , Proteína C-Reativa/metabolismo , Cálcio/sangue , Estudos de Casos e Controles , Doenças do Cão/sangue , Cães , Feminino , Hemoperitônio/sangue , Masculino , Neoplasias/sangue , Hormônio Paratireóideo/sangue , Fósforo/sangue , Fatores de Risco , Vitamina D/sangue
15.
Artigo em Inglês | MEDLINE | ID: mdl-26453030

RESUMO

OBJECTIVE: To describe the use of contrast-enhanced ultrasonography (CEUS) for the detection of active renal hemorrhage in a dog with spontaneous kidney rupture resulting in hemoperitoneum. CASE SUMMARY: A 9-month-old, sexually intact male Boxer dog presented for acute collapse, abdominal pain, and tachycardia. Physical examination findings were consistent with hypovolemia and acute abdomen. B-mode ultrasonography revealed peritoneal effusion and a right kidney mass. Subsequently, a CEUS study was performed on the right kidney, which demonstrated active hemorrhage from that kidney resulting in both hemoretroperitoneum and hemoperitoneum. At exploratory surgery, ultrasonographic findings were confirmed and a right nephrectomy was performed. Histopathology demonstrated severe parenchymal alterations along with the presence of nematode larvae. Fecal and urine testing for the presence of parasitic ova were negative. Identification of the larvae was inconclusive. At 30 days postoperatively, repeat B-mode ultrasound and clinicopathologic testing was unremarkable. The dog was alive at 1 year postsurgery with no ill effects. NEW OR UNIQUE INFORMATION PROVIDED: To the authors' knowledge, this is the first report of CEUS for the detection of active hemorrhage from a kidney resulting in hemoretroperitoneum and hemoperitoneum in a dog. Although rare, the finding of nematode larvae within the renal parenchyma may have been the cause of kidney rupture. Importantly, surgical removal of the kidney was curative. Benign processes causing kidney rupture such as parasitic infestation should be considered in the working diagnosis as related to geographical location.


Assuntos
Doenças do Cão/diagnóstico por imagem , Hemoperitônio/veterinária , Hemorragia/veterinária , Nefropatias/veterinária , Abdome Agudo , Dor Abdominal , Animais , Meios de Contraste , Doenças do Cão/diagnóstico , Doenças do Cão/etiologia , Cães , Hemoperitônio/etiologia , Hemorragia/complicações , Hemorragia/diagnóstico , Hemorragia/diagnóstico por imagem , Rim/diagnóstico por imagem , Rim/patologia , Nefropatias/complicações , Nefropatias/diagnóstico , Nefropatias/diagnóstico por imagem , Masculino , Ruptura Espontânea/diagnóstico , Ruptura Espontânea/veterinária , Ultrassonografia
16.
Artigo em Inglês | MEDLINE | ID: mdl-26176976

RESUMO

OBJECTIVE: To describe the clinical features, diagnostic findings, treatment, and outcome of a dog with acute abdominal pain and hemoperitoneum secondary to a presumptive intraperitoneal (IP) snakebite. CASE SUMMARY: A 10-month-old castrated male mixed-breed dog was evaluated for suspected snake envenomation. The dog presented recumbent and tachycardic with signs of severe abdominal pain. Two cutaneous puncture wounds and hemoperitoneum were discovered during evaluation. Ultrasonographic examination revealed communication of the wounds with the peritoneal cavity. The dog was treated with supportive care, parenteral analgesia, packed red blood cell and fresh frozen plasma transfusions, crotalid antivenom, and placement of an IP catheter to provide local analgesia. The dog recovered fully and was discharged 5 days after initial presentation. NEW OR UNIQUE INFORMATION PROVIDED: To our knowledge, this is the first report of IP envenomation accompanied by hemorrhage treated with continuous IP analgesia in the veterinary literature.


Assuntos
Dor Abdominal/veterinária , Antivenenos/uso terapêutico , Doenças do Cão/etiologia , Hemoperitônio/veterinária , Mordeduras de Serpentes/veterinária , Viperidae , Dor Abdominal/etiologia , Animais , Doenças do Cão/patologia , Cães , Hemoperitônio/etiologia , Masculino , Mordeduras de Serpentes/complicações , Mordeduras de Serpentes/terapia
17.
Schweiz Arch Tierheilkd ; 157(6): 339-43, 2015 Jun.
Artigo em Alemão | MEDLINE | ID: mdl-26753349

RESUMO

This case report describes the clinical, ultrasonographic, pathological and histological findings in a two-year-old Swiss Braunvieh cow with granulosa cell tumor and metastases in the abdomen and thorax. The cow was ill and had tachycardia, coughing, increased breath sounds, positive reticular foreign body tests and a tense abdominal wall. Ultrasonography revealed a massive accumulation of hypoechoic fluid in the thorax and abdomen, and abdomino- and thoracocentesis yielded red fluid indicative of abdominal and thoracic haemorrhage. Because of a poor prognosis, the cow was euthanized and examined postmortem. Multiple nodular lesions were seen in the omentum, liver, spleen and lungs. The left ovary was grossly enlarged and nodular in appearance. Histological examination of the lesions revealed granulosa cell tumour of the left ovary and metastases in the omentum, liver, spleen and lungs.


Assuntos
Doenças dos Bovinos/etiologia , Tumor de Células da Granulosa/veterinária , Hemoperitônio/veterinária , Hemotórax/veterinária , Neoplasias Ovarianas/veterinária , Neoplasias Abdominais/secundário , Neoplasias Abdominais/veterinária , Animais , Bovinos , Doenças dos Bovinos/diagnóstico por imagem , Doenças dos Bovinos/patologia , Eutanásia Animal , Feminino , Tumor de Células da Granulosa/complicações , Tumor de Células da Granulosa/patologia , Tumor de Células da Granulosa/secundário , Hemoperitônio/diagnóstico por imagem , Hemoperitônio/etiologia , Hemoperitônio/patologia , Hemotórax/diagnóstico por imagem , Hemotórax/etiologia , Hemotórax/patologia , Neoplasias Ovarianas/complicações , Neoplasias Ovarianas/patologia , Prognóstico , Neoplasias Torácicas/secundário , Neoplasias Torácicas/veterinária , Ultrassonografia
18.
Vet Surg ; 44(3): 379-85, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25039980

RESUMO

OBJECTIVE: To investigate postoperative hemoperitoneum in a population of horses that had surgery for colic. STUDY DESIGN: Retrospective case series. ANIMALS: Horses (n = 23). METHODS: Preoperative, intraoperative, and postoperative information was obtained from medical records (1985-2012) of horses with postoperative hemoperitoneum after emergency exploratory celiotomy. Pre-existing hemoperitoneum during surgery and nonsurgical hemoperitoneum were excluded. RESULTS: Of 4520 horses that had emergency exploratory celiotomy for gastrointestinal disease, 23 horses met inclusion criteria; an incidence of 0.5%. Horse signalment approximated the colic population, although Thoroughbreds were significantly overrepresented. Hemoperitoneum was significantly associated with intestinal resection. Postoperative hemoperitoneum was recognized a mean (± SD) of 1.0 ± 0.7 days after surgery and associated with tachycardia, decreasing hematocrit, incisional drainage, or ultrasonographic identification of swirling, echogenic abdominal fluid. Primary treatments included intravenous fluid therapy (n = 23), colloid support (20), blood transfusion (13), and antifibrinolytic agents (11). Fifteen horses (65%) survived to discharge, which was associated with admission lactate and days of hospitalization. CONCLUSIONS: Postoperative hemoperitoneum is a rare complication of exploratory celiotomy in horses that should be considered when there are signs of abdominal discomfort and declining hematocrit in the early postoperative period. Prognosis is guarded because of potential sequelae of septic peritonitis and adhesion formation.


Assuntos
Cólica/veterinária , Gastroenteropatias/veterinária , Hemoperitônio/veterinária , Doenças dos Cavalos/cirurgia , Laparoscopia/veterinária , Complicações Pós-Operatórias/veterinária , Animais , Cólica/cirurgia , Tratamento de Emergência/veterinária , Feminino , Gastroenteropatias/cirurgia , Hemoperitônio/etiologia , Hemoperitônio/terapia , Cavalos , Laparoscopia/efeitos adversos , Tempo de Internação , Masculino , Complicações Pós-Operatórias/terapia , Estudos Retrospectivos
19.
J Vet Diagn Invest ; 27(1): 112-6, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25525145

RESUMO

Five horses originating from 4 different California race tracks were submitted to the California Animal Health and Food Safety Laboratory for necropsy and diagnostic workup. The 5 horses had a history of sudden collapse and death during exercise. In all of them, massive hemoperitoneum and hemorrhages in other cavities or organs were observed. The liver from these 5 animals and from 27 horses that had been euthanized due to catastrophic leg injuries (controls) were subjected to a rodenticide anticoagulant screen. Traces of brodifacoum, diphacinone, or bromadiolone were detected in the 5 horses with massive bleeding (5/5), and no traces of rodenticides were detected in control horses (0/27). Other frequent causes of massive hemorrhages in horses were ruled out in 4 of the cases; one of the horses had a pelvic fracture. Although only traces of anticoagulants were found in the livers of these horses and the role of these substances in the massive bleeding remains uncertain, it is speculated that exercise-related increases in blood pressure may have reduced the threshold for toxicity of these anticoagulants.


Assuntos
Anticoagulantes/toxicidade , Hemorragia/veterinária , Doenças dos Cavalos/induzido quimicamente , Condicionamento Físico Animal , Rodenticidas/toxicidade , 4-Hidroxicumarinas/toxicidade , Animais , California , Hemoperitônio/induzido quimicamente , Hemoperitônio/veterinária , Hemorragia/induzido quimicamente , Cavalos , Fígado/química , Masculino , Fenindiona/análogos & derivados , Fenindiona/toxicidade
20.
J Am Anim Hosp Assoc ; 50(3): 159-66, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24659726

RESUMO

Treatment for hemorrhagic shock secondary to a spontaneous hemoperitoneum includes restoration of IV volume and surgical control of hemorrhage. This study was designed to determine if limited fluid volume resuscitation (LFVR) with hypertonic saline (HS) and hyperoncotic fluids (hydroxyethylstarch [HES]) results in more rapid cardiovascular stabilization in dogs with spontaneous hemoperitoneum versus conventional resuscitation (CR) with large volume resuscitation. Eighteen client-owned dogs presenting in hemorrhagic shock with a spontaneous hemoperitoneum were enrolled. Dogs were randomized to be fluid resuscitated with up to 90 mL/kg of an isotonic crystalloid (CR group) or up to 8 mL/kg of 7.2% Na chloride (i.e., HS) combined with up to 10 mL/kg of 6% HES. Measurements of vital signs, lactate, packed cell volume (PCV), total solids (TS), and blood pressure were made at standard time points. The primary end point was time to stabilization of hemodynamic parameters (measured in min). Dogs in the LFVR group achieved hemodynamic stabilization significantly faster (20 min; range, 10-25 min) than those in the CR group (35 min; range, 15-50 min; P = .027). Future studies are warranted to further investigate potential benefits associated with LFVR in dogs with spontaneous hemoperitoneum.


Assuntos
Doenças do Cão/terapia , Hemoperitônio/veterinária , Ressuscitação/veterinária , Choque Hemorrágico/veterinária , Animais , Pressão Sanguínea , Cães , Hidratação/métodos , Hemoperitônio/terapia , Derivados de Hidroxietil Amido/administração & dosagem , Projetos Piloto , Ressuscitação/métodos , Solução Salina Hipertônica/administração & dosagem , Choque Hemorrágico/terapia , Resultado do Tratamento
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