Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 317
Filtrar
3.
Drugs Aging ; 36(3): 235-245, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30637685

RESUMO

Aging skin is subject to morphological change due to both intrinsic (skin tone, genetics, endogenous hormones) and extrinsic (chronic sun exposure, medications, exogenous pigments) factors. The broad spectrum of transformation includes both hypo- and hyperpigmentation. Although cutaneous pigmentary disorders are common in younger individuals, certain disorders are more prevalent in the geriatric population. This article reviews the epidemiology, pathophysiology, clinical appearance, treatment, and prognosis of pigmentary lesions that are predominant in the elderly.


Assuntos
Transtornos da Pigmentação/diagnóstico , Transtornos da Pigmentação/terapia , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Hiperpigmentação/diagnóstico , Hiperpigmentação/epidemiologia , Hiperpigmentação/terapia , Hipopigmentação/diagnóstico , Hipopigmentação/epidemiologia , Hipopigmentação/terapia , Masculino , Pessoa de Meia-Idade , Transtornos da Pigmentação/epidemiologia
4.
J Am Acad Dermatol ; 80(5): 1233-1250.e10, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30236514

RESUMO

Acquired hypopigmented skin changes are commonly encountered by dermatologists. Although hypopigmentation is often asymptomatic and benign, occasional serious and disabling conditions present with cutaneous hypopigmentation. A thorough history and physical examination, centered on disease distribution and morphologic findings, can aid in delineating the causes of acquired hypopigmented disorders. The second article in this 2-part continuing medical education series focuses on conditions with a hypopigmented phenotype. Early diagnosis and appropriate management of these disorders can improve a patient's quality of life, halt disease progression, and prevent irreversible disability.


Assuntos
Hipopigmentação/etiologia , Micose Fungoide/complicações , Neoplasias Cutâneas/complicações , Intoxicação por Arsênico/complicações , Dermatite/complicações , Humanos , Hipopigmentação/diagnóstico , Hipopigmentação/terapia , Leishmaniose Visceral/complicações , Hanseníase Paucibacilar/complicações , Micose Fungoide/diagnóstico , Neoplasias Cutâneas/diagnóstico , Sífilis/complicações , Tinha Versicolor/complicações , Tinha Versicolor/tratamento farmacológico
12.
Pediatr Dermatol ; 35(6): e404-e405, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30152562

RESUMO

We present a case of an otherwise healthy infant with a localized patch of phylloid hypopigmentation bordered by terminal hairs on the back. We believe that this is a unique clinical entity and propose the term "phylloid terminal hair nevus." We believe that this is a localized form of phylloid hypomelanosis that is not associated with extracutaneous abnormalities.


Assuntos
Hipopigmentação/diagnóstico , Pele/patologia , Dermoscopia , Diagnóstico Diferencial , Feminino , Humanos , Recém-Nascido , Mosaicismo , Nevo/diagnóstico
14.
BMJ Case Rep ; 20182018 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-29982187

RESUMO

Hypomelanosis of Ito is a rare neurocutaneous syndrome. Cutaneous involvement is characterised by streaks and swirls of hypopigmentation arranged in a Blaschkoid pattern. Neural involvement along with other systemic features are seen. We report a case of a 13-year-old boy who presented with the characteristic skin involvement of hypomelanosis of Ito, mental retardation, teeth abnormalities and gynaecomastia along with psoriasis.


Assuntos
Ginecomastia/complicações , Hipopigmentação/complicações , Anormalidades Dentárias/etiologia , Adolescente , Diagnóstico Diferencial , Humanos , Hipopigmentação/diagnóstico , Deficiência Intelectual/etiologia , Masculino , Psoríase/etiologia
16.
Cutis ; 101(4): 297-300, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29763479

RESUMO

Progressive macular hypomelanosis (PMH) is a skin disorder that historically has been described as having a predominantly truncal distribution. We report 4 adult cases of PMH with facial involvement. The diagnosis was made for all 4 patients after excluding other hypopigmented diseases. This report underscores the importance of considering PMH as part of the differential for hypopigmented lesions on the face.


Assuntos
Hipopigmentação/diagnóstico , Adulto , Face , Feminino , Humanos , Hipopigmentação/patologia , Masculino , Pessoa de Meia-Idade
19.
Int J Dermatol ; 57(3): 306-312, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29318586

RESUMO

BACKGROUND: Hypopigmented mycosis fungoides (hMF) is a rare subtype of mycosis fungoides. The aim of this study was to identify the clinical-epidemiological profile of our patient group and also to provide additional information about treatment responses and prognosis. METHODS: This is a cross-sectional retrospective observational study, with exploratory analysis. The outcome variables were disease progression and related death. RESULTS: Twenty patients with hMF were selected from a group of 102 patients diagnosed with MF. There was no gender difference (10 females and 10 males). Mean age at diagnosis was 43.85 years, and most patients had mixed or black skin color. The mean time between the onset of the lesions and the diagnosis was 66.75 months. Patients were equally distributed in stages IA (50%) and IB (50%). Photochemotherapy (psoralen and ultraviolet A) was the predominant therapeutic modality. The mean follow-up time was 7.25 years. In 10%, disease progression was observed. Death related to the disease occurred in one patient. CONCLUSIONS: The clinical and epidemiological profile of patients with hypopigmented MF found in our sample is in agreement with what is described in the literature, with the exception of the age at diagnosis, higher than expected. Diagnostic delay time, despite long, is also consistent with the medical literature; however, in this sample, we had two cases of disease progression, with death of one patient, despite the treatment, which is extremely important since hypopigmented MF is usually associated with good prognosis.


Assuntos
Hipopigmentação/diagnóstico , Hipopigmentação/tratamento farmacológico , Micose Fungoide/diagnóstico , Micose Fungoide/tratamento farmacológico , Adolescente , Adulto , Idade de Início , Idoso , Brasil/epidemiologia , Criança , Estudos Transversais , Diagnóstico Tardio , Progressão da Doença , Feminino , Seguimentos , Humanos , Hipopigmentação/complicações , Hipopigmentação/epidemiologia , Masculino , Pessoa de Meia-Idade , Micose Fungoide/complicações , Micose Fungoide/epidemiologia , Terapia PUVA , Estudos Retrospectivos , Taxa de Sobrevida , Adulto Jovem
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA