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1.
Stud Health Technol Inform ; 267: 142-149, 2019 Sep 03.
Artigo em Inglês | MEDLINE | ID: mdl-31483266

RESUMO

Translational research in the medical sector is dependent on clear communication between all participants. Visualization helps to represent data from different sources in a comprehensible way across disciplines. Existing tools for clinical data management are usually monolithic and technically challenging to set up, others require a transformation into specific data models while providing mostly non-interactive visualizations or being specialized to very particular use cases. Statistical programming languages (R, Julia) on the other hand offer great flexibility in data analytics, but are harder to access for clinicians with little to no programming expertise. Our software, the Medical Data Explorer (MedEx), aims to fill this gap as light-weight, intuitive, web-based solution with simple data import routes. We couple a modern dynamic web interface with an in-memory database solution for near real-time responsiveness. MedEx provides multiple visualization options (Scatterplot, correlation heatmap, bar chart, grouped boxplot, grouped histogram, coplot) to get an easy overview on the loaded data as well as to perform pattern discovery and elementary statistics. We demonstrate the utility of MedEx, by example, on data from the cardiology research warehouse of Heidelberg University Hospital. In summary, our tool empowers clinicians to conduct their own interactive exploratory data analysis.


Assuntos
Software , Ciência de Dados , Linguagens de Programação , Interface Usuário-Computador
2.
Stud Health Technol Inform ; 264: 1882-1883, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438390

RESUMO

The multidisciplinary aspect of patient care is not yet sufficiently taken into account in hospital ward management. By gathering data from the administrative database of hospital stays and the operating theaters management software, we developed a graphical user interface to visualize and analyze the pathways of patients who underwent thoracic surgery in the Nantes University Hospital of France in 2016 and 2017.


Assuntos
Cirurgia Torácica , Bases de Dados Factuais , França , Humanos , Tempo de Internação , Software , Interface Usuário-Computador
3.
Stud Health Technol Inform ; 264: 1953-1954, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438424

RESUMO

Medical information systems and care robots are two typical examples of human computer interaction in health care. Although used in a stressful environment, effects on mental workload and acceptance are hardly evaluated. We conducted an experimental design including collaborative robotics and eye tracking in a nursing situation to test the practicability and plausibility of eye tracking as a measuring method for workload. Results showed that eye tracking is feasible if context factors are adjusted. Data reduction and classification of tasks are necessary.


Assuntos
Carga de Trabalho , Humanos , Robótica , Interface Usuário-Computador
4.
Stud Health Technol Inform ; 264: 1974-1975, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438435

RESUMO

We developed and evaluated the usability of Check-up Surgery, a surgery application from the mApp® Platform. The Usability Engineering Cycle was used as method of development. The results showed that the Check-up Surgery application had excellent usability criteria with an average of 4.63 to 4.70 by 81% of the evaluators. For all the interviewees there was statistical significance in relation to the usability criteria of the application, with pValue ≤.05.


Assuntos
Interface Usuário-Computador , Cirurgia Geral
5.
Stud Health Technol Inform ; 264: 1976-1977, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438436

RESUMO

Eye-tracking has long been used to assess usability for the public web. Recently, it is used to assess user behavior with electronic health records (EHRs). We conducted a scoping review of studies involving eye-tracking for usability of EHRs to determine the current state. Three main themes emerged: studies of usual use of systems, development of new methods, and studies of new features. Detailed user behaviors revealed by eye-tracking can contribute valuable information to redesign efforts.


Assuntos
Registros Eletrônicos de Saúde , Interface Usuário-Computador
6.
Stud Health Technol Inform ; 264: 1978-1979, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438437

RESUMO

IRIS is an automated coding software for the causes of death. It is used in many European countries for the production of death statistics. The purpose of our work was to study the usability of this software in Africa where the quality of statistics is insufficient. For this, we have developed a device consisting of two software: "collector" and "encoder" cooperating via the same database.


Assuntos
Software , Interface Usuário-Computador , África , Causas de Morte , Bases de Dados Factuais , Europa (Continente)
7.
Stud Health Technol Inform ; 264: 2005-2006, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438451

RESUMO

Family health history (FHx) is vital in early detection of genetic diseases. This research studied two different FHx collection interface and compared them based on the IBM CSUQ usability metrics. We found the conversational interface to be significantly better in terms of overall satisfaction, system usefulness, interface quality and information quality than the traditional interface.


Assuntos
Comunicação , Interface Usuário-Computador , Anamnese
8.
BMC Bioinformatics ; 20(1): 417, 2019 Aug 13.
Artigo em Inglês | MEDLINE | ID: mdl-31409281

RESUMO

BACKGROUND: The development of high throughput sequencing techniques provides us with the possibilities to obtain large data sets, which capture the effect of dynamic perturbations on cellular processes. However, because of the dynamic nature of these processes, the analysis of the results is challenging. Therefore, there is a great need for bioinformatics tools that address this problem. RESULTS: Here we present DynOVis, a network visualization tool that can capture dynamic dose-over-time effects in biological networks. DynOVis is an integrated work frame of R packages and JavaScript libraries and offers a force-directed graph network style, involving multiple network analysis methods such as degree threshold, but more importantly, it allows for node expression animations as well as a frame-by-frame view of the dynamic exposure. Valuable biological information can be highlighted on the nodes in the network, by the integration of various databases within DynOVis. This information includes pathway-to-gene associations from ConsensusPathDB, disease-to-gene associations from the Comparative Toxicogenomics databases, as well as Entrez gene ID, gene symbol, gene synonyms and gene type from the NCBI database. CONCLUSIONS: DynOVis could be a useful tool to analyse biological networks which have a dynamic nature. It can visualize the dynamic perturbations in biological networks and allows the user to investigate the changes over time. The integrated data from various online databases makes it easy to identify the biological relevance of nodes in the network. With DynOVis we offer a service that is easy to use and does not require any bioinformatics skills to visualize a network.


Assuntos
Redes Reguladoras de Genes , Interface Usuário-Computador , Acetaminofen/farmacologia , Biologia Computacional/métodos , Bases de Dados Factuais , Humanos , NF-kappa B/metabolismo , Transdução de Sinais/efeitos dos fármacos , Transdução de Sinais/genética
9.
BMC Bioinformatics ; 20(1): 418, 2019 Aug 13.
Artigo em Inglês | MEDLINE | ID: mdl-31409293

RESUMO

BACKGROUND: Standard RNAseq methods using bulk RNA and recent single-cell RNAseq methods use DNA barcodes to identify samples and cells, and the barcoded cDNAs are pooled into a library pool before high throughput sequencing. In cases of single-cell and low-input RNAseq methods, the library is further amplified by PCR after the pooling. Preparation of hundreds or more samples for a large study often requires multiple library pools. However, sometimes correlation between expression profiles among the libraries is low and batch effect biases make integration of data between library pools difficult. RESULTS: We investigated 166 technical replicates in 14 RNAseq libraries made using the STRT method. The patterns of the library biases differed by genes, and uneven library yields were associated with library biases. The former bias was corrected using the NBGLM-LBC algorithm, which we present in the current study. The latter bias could not be corrected directly, but could be solved by omitting libraries with particularly low yields. A simulation experiment suggested that the library bias correction using NBGLM-LBC requires a consistent sample layout. The NBGLM-LBC correction method was applied to an expression profile for a cohort study of childhood acute respiratory illness, and the library biases were resolved. CONCLUSIONS: The R source code for the library bias correction named NBGLM-LBC is available at https://shka.github.io/NBGLM-LBC and https://shka.bitbucket.io/NBGLM-LBC . This method is applicable to correct the library biases in various studies that use highly multiplexed sequencing-based profiling methods with a consistent sample layout with samples to be compared (e.g., "cases" and "controls") equally distributed in each library.


Assuntos
Biblioteca Gênica , Análise de Sequência de RNA/métodos , Transcriptoma , Linhagem Celular , Análise por Conglomerados , Sequenciamento de Nucleotídeos em Larga Escala , Humanos , Análise de Componente Principal , RNA/química , RNA/metabolismo , Interface Usuário-Computador
10.
BMC Evol Biol ; 19(1): 163, 2019 08 02.
Artigo em Inglês | MEDLINE | ID: mdl-31375065

RESUMO

BACKGROUND: Ancestral character states computed from the combination of phylogenetic trees with extrinsic traits are used to decipher evolutionary scenarios in various research fields such as phylogeography, epidemiology, and ecology. Despite the existence of powerful methods and software in ancestral character state inference, difficulties may arise when interpreting the outputs of such inferences. The growing complexity of data (trees, annotations), the diversity of optimization criteria for computing trees and ancestral character states, the combinatorial explosion of potential evolutionary scenarios if some ancestral characters states do not stand out clearly from others, requires the design of new methods to explore associations of phylogenetic trees with extrinsic traits, to ease the visualization and interpretation of evolutionary scenarios. RESULT: We developed PastView, a user-friendly interface that includes numerical and graphical features to help users to import and/or compute ancestral character states from discrete variables and extract ancestral scenarios as sets of successive transitions of character states from the tree root to its leaves. PastView provides summarized views such as transition maps and integrates comparative tools to highlight agreements or discrepancies between methods of ancestral annotations inference. CONCLUSION: The main contribution of PastView is to assemble known numerical and graphical methods into a multi-maps graphical user interface dedicated to the computing, searching and viewing of evolutionary scenarios based on phylogenetic trees and ancestral character states. PastView is available publicly as a standalone software on www.pastview.org .


Assuntos
Filogenia , Software , Interface Usuário-Computador , Albânia/epidemiologia , Dengue/epidemiologia , Vírus da Dengue/genética , Infecções por HIV/epidemiologia , HIV-1/genética , Humanos , Fenótipo , Filogeografia
11.
BMC Bioinformatics ; 20(1): 422, 2019 Aug 14.
Artigo em Inglês | MEDLINE | ID: mdl-31412768

RESUMO

BACKGROUND: One of the main issues in the automated protein function prediction (AFP) problem is the integration of multiple networked data sources. The UNIPred algorithm was thereby proposed to efficiently integrate -in a function-specific fashion- the protein networks by taking into account the imbalance that characterizes protein annotations, and to subsequently predict novel hypotheses about unannotated proteins. UNIPred is publicly available as R code, which might result of limited usage for non-expert users. Moreover, its application requires efforts in the acquisition and preparation of the networks to be integrated. Finally, the UNIPred source code does not handle the visualization of the resulting consensus network, whereas suitable views of the network topology are necessary to explore and interpret existing protein relationships. RESULTS: We address the aforementioned issues by proposing UNIPred-Web, a user-friendly Web tool for the application of the UNIPred algorithm to a variety of biomolecular networks, already supplied by the system, and for the visualization and exploration of protein networks. We support different organisms and different types of networks -e.g., co-expression, shared domains and physical interaction networks. Users are supported in the different phases of the process, ranging from the selection of the networks and the protein function to be predicted, to the navigation of the integrated network. The system also supports the upload of user-defined protein networks. The vertex-centric and the highly interactive approach of UNIPred-Web allow a narrow exploration of specific proteins, and an interactive analysis of large sub-networks with only a few mouse clicks. CONCLUSIONS: UNIPred-Web offers a practical and intuitive (visual) guidance to biologists interested in gaining insights into protein biomolecular functions. UNIPred-Web provides facilities for the integration of networks, and supplies a framework for the imbalance-aware protein network integration of nine organisms, the prediction of thousands of GO protein functions, and a easy-to-use graphical interface for the visual analysis, navigation and interpretation of the integrated networks and of the functional predictions.


Assuntos
Biologia Computacional/métodos , Internet , Mapas de Interação de Proteínas , Proteínas/metabolismo , Software , Algoritmos , Interface Usuário-Computador
12.
Stud Health Technol Inform ; 265: 80-85, 2019 Aug 09.
Artigo em Inglês | MEDLINE | ID: mdl-31431581

RESUMO

The usability of healthcare information technology has become a major issue in health informatics. There have been many reports of systems that have been deemed unusable by end users such as clinicians and a growing body of usability studies have been reported in the literature. The issue of how to fruitfully analyze and code usability study data in a meaningful way that can lead to optimized and more efficient systems has remained to be fully detailed. In this paper we describe our work in developing and organizing a principled video coding scheme that builds from our previous work in a couple of areas. We include video coding categories we have developed for understanding problems and issues with human-computer interaction. In addition, we integrate this coding scheme with categories we have used to characterize human cognition, such as clinical reasoning and decision making, in isolation of technology use. The resultant new scheme thus incorporates coding categories that can used to evaluate both usability issues (applying categories from human-computer interaction) and human cognition, in order to assess the impact of technology on clinical reasoning and decision making.


Assuntos
Tomada de Decisão Clínica , Informática Médica , Cognição , Computadores , Humanos , Interface Usuário-Computador
13.
Stud Health Technol Inform ; 264: 1036-1040, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438082

RESUMO

Health information exchange (HIE) is implemented in Quebec, Canada to improve the exchange and use of clinical information for decision making in the province's health care system. The objective of this mixed-method approach study was to evaluate the usage, usability, and usefulness of an electronic health record (EHR) to access and import clinical information from a centralized HIE. First, a heuristic analysis was performed of three different commercial EHRs, using end users to analyze the integration feature through think aloud protocols. Second, interviews were conducted with advanced users to describe the usefulness. Third, usage data were analyzed to describe the level of use of each data domain, per EHR and user. The results show that usefulness is high for medication data; leading to greater use of this domain, its relation to integration, and meets the needs of general practitioners. Difficulties in the implementation processes reduced the potential of this system.


Assuntos
Troca de Informação em Saúde , Registros Eletrônicos de Saúde , Quebeque , Interface Usuário-Computador
14.
Stud Health Technol Inform ; 264: 1710-1711, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438305

RESUMO

Using telemedicine to provide care is an attractive alternative for patients. However, few studies have examined the demographics of the patients using virtual care. In this paper, we investigate the demographic features of the Virtual Care (VC) users; Age, gender, roles, and preferred methods of communication are studied.


Assuntos
Comunicação , Telemedicina , Demografia , Humanos , Interface Usuário-Computador
15.
Stud Health Technol Inform ; 263: 49-63, 2019 Jul 30.
Artigo em Inglês | MEDLINE | ID: mdl-31411152

RESUMO

mHealth can offer great potential for the self-management of health conditions and facilitating health services. It is therefore imperative that the design of mHealth systems afford optimum efficacy and effectiveness. Involving end users in collaborative decision making is an essential aspect of increasing acceptance of the treatment intervention. Involving users in the design and evaluation of mHealth systems helps to enable a better understanding of the complexity of user needs and how to incorporate this information effectively into the design process. This chapter discusses how Activity Theory can help to provide a theoretical lens for a User Centred Design framework in the design of mHealth systems. A general overview of Activity Theory and User Centred Design are provided, followed by their application in mHealth. Two use cases are provided that demonstrate how Activity Theory has helped provide a broader contextual analysis to a User Centred iterative approach to system design and evaluation.


Assuntos
Autogestão , Telemedicina , Interface Usuário-Computador , Computadores , Humanos
16.
Stud Health Technol Inform ; 264: 74-78, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31437888

RESUMO

Personalized medicine implies reducing invasiveness of therapeutic procedures. Although interventional radiology proved a very interesting alternative to surgical procedures, it still raises concerns due to the irradiation dose received by the medical team (and by the patient). We propose a novel concept allowing to reduce very significantly the irradiation dose during the phases where tools inserted in the patient have to be tracked with respect to previously acquired images. This implies inserting a miniaturized X-ray detector in the tip of the tools, and reducing the dose by a "rotating collimator". We demonstrate that real-time processing of the signals allows accurate localization of the tip of the tools, with a dose reduction of at least ten times.


Assuntos
Cateterismo , Radiologia Intervencionista , Interface Usuário-Computador , Fluoroscopia , Humanos , Doses de Radiação , Radiologia Intervencionista/instrumentação
17.
Stud Health Technol Inform ; 264: 1811-1812, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438356

RESUMO

Electronic health records (EHRs) have been shown to improve safety and quality. However, usability and safety issues with EHRs have been reported. The current state of the art in usability testing is to have clinicians conduct simulated activities in a usability lab. In this poster, we describe our experience with continuous recording of real-world EHR use to improve safety and usability.


Assuntos
Registros Eletrônicos de Saúde , Interface Usuário-Computador , Gravação em Vídeo
18.
Zhongguo Yi Liao Qi Xie Za Zhi ; 43(4): 248-251, 2019 Jul 30.
Artigo em Chinês | MEDLINE | ID: mdl-31460713

RESUMO

We developed a new the musculoskeletal anatomic database software based on internet. This article presents the design objective and basic routes of the software, further present the technical plan, software functionality and service objects. This software is used to store the anatomic data of musculoskeletal system, that allows the users to enquire and do statistial analysis through the large amount of anatomic data, that guides the doctors to design operative schemes, that provides technical supports for medicine and industry fields.


Assuntos
Internet , Sistema Musculoesquelético , Software , Bases de Dados Factuais , Humanos , Interface Usuário-Computador
19.
Stud Health Technol Inform ; 264: 644-648, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438003

RESUMO

This paper describes work to assess the feasibility of using a decision support tool to help patients with chronic conditions, specifically stroke, manage their condition in collaboration with their carers and the health care professionals who are looking after them. The system contains several novel elements: the integration of data from commercial wellness sensors, electronic health records and clinical guidelines; the use of computational argumentation to track the source of data and to resolve conflicts and make recommendations; and argumentation-based dialogue to support interaction with patients. The proposed approach is implemented as an application that can run on smart devices (e.g. tablets). The users have personalised dashboards where they can visualise their health data and interact with a conversational chatbot that provides further explanations about their overall well-being.


Assuntos
Sistemas de Apoio a Decisões Clínicas , Registros Eletrônicos de Saúde , Sistemas Especialistas , Humanos , Software , Interface Usuário-Computador
20.
Stud Health Technol Inform ; 264: 649-653, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31438004

RESUMO

Usability of health information technology (HIT) remains a predominant concern - one often exacerbated by clinicians' need to access information created by many different professionals in different settings, often using very dissimilar EHRs or even different configurations of the same EHR. Because of these variations, we argue that we must no longer think of usability as anchored in one setting, one EHR, one data standard, or one type of clinician. Rather, usability must be understood as a collective and constantly evolving process. This paper seeks to address that reality by 1) substantially expanding our previously-developed conceptual matrix of the wide range of settings and interfaces comprising modern HIT and 2) presenting actual examples of EHR usability issues with similar data but very different displays or processes.


Assuntos
Sistemas de Informação em Saúde , Informática Médica , Assistência à Saúde , Registros Eletrônicos de Saúde , Interface Usuário-Computador
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