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1.
PLoS One ; 15(10): e0239886, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33006990

RESUMO

BACKGROUND: Syndromic surveillance through web or phone-based polling has been used to track the course of infectious diseases worldwide. Our study objective was to describe the characteristics, symptoms, and self-reported testing rates of respondents in three different COVID-19 symptom surveys in Canada. METHODS: This was a cross-sectional study using three distinct Canada-wide web-based surveys, and phone polling in Ontario. All three sources contained self-reported information on COVID-19 symptoms and testing. In addition to describing respondent characteristics, we examined symptom frequency and the testing rate among the symptomatic, as well as rates of symptoms and testing across respondent groups. RESULTS: We found that over March- April 2020, 1.6% of respondents experienced a symptom on the day of their survey, 15% of Ontario households had a symptom in the previous week, and 44% of Canada-wide respondents had a symptom in the previous month. Across the three surveys, SARS-CoV-2-testing was reported in 2-9% of symptomatic responses. Women, younger and middle-aged adults (versus older adults) and Indigenous/First nations/Inuit/Métis were more likely to report at least one symptom, and visible minorities were more likely to report the combination of fever with cough or shortness of breath. INTERPRETATION: The low rate of testing among those reporting symptoms suggests significant opportunity to expand testing among community-dwelling residents of Canada. Syndromic surveillance data can supplement public health reports and provide much-needed context to gauge the adequacy of SARS-CoV-2 testing rates.


Assuntos
Técnicas de Laboratório Clínico/estatística & dados numéricos , Infecções por Coronavirus/epidemiologia , Pneumonia Viral/epidemiologia , Autorrelato/estatística & dados numéricos , Vigilância de Evento Sentinela , Adulto , Idoso , Canadá/epidemiologia , Infecções por Coronavirus/diagnóstico , Estudos Transversais , Feminino , Humanos , Internet , Masculino , Pessoa de Meia-Idade , Pandemias , Pneumonia Viral/diagnóstico , Prevalência , Telefone
2.
Psychiatr Danub ; 32(Suppl 3): 382-385, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33030458

RESUMO

INTRODUCTION: Addiction is not solely "substance dependence". Diminished control is a core defining concept of psychoactive substance addiction. Several behaviors, besides psychoactive substance ingestion, produce short-term reward that may engender diminished control over the behavior. Growing evidence suggests that behavioral addictions resemble substance addictions in many domains, including phenomenology, tolerance, comorbidity, overlapping genetic contribution, neurobiological mechanisms, and response to treatment. This similarity has given rise to the concept of non-substance or behavioral addictions, i.e., syndromes analogous to substance addiction, but with a behavioral focus. The type of excessive behaviors identified as being addictive include gambling, use of computers, playing video games, use of the internet, exercise, and shopping. Behavioral addictions have been proposed as a new class in DSM-5, but the only category included is gambling disorder. Internet gaming disorder is included in the appendix as a condition for further study. The ICD-11 included also the definition of a new disorder, gaming disorder. To present actual knowledge about behavioral addictions in childhood and adolescence. METHODS: Analysis of data in available literature in data basis and textbooks. RESULTS: Some behavioral addictions are becoming more common in children and adolescents. Dominant are gaming and gambling addiction that are also best researched. CONCLUSIONS: Behavioral addiction becomes an epidemic in children and adolescents.


Assuntos
Comportamento Aditivo/epidemiologia , Internet , Adolescente , Criança , Jogo de Azar/epidemiologia , Humanos , Pandemias , Comportamento Sexual , Jogos de Vídeo
3.
Klin Monbl Augenheilkd ; 237(10): 1172-1176, 2020 Oct.
Artigo em Inglês, Alemão | MEDLINE | ID: mdl-33059376

RESUMO

The digital media becomes more and more common in our everyday lives. So it is not surprising that technical progress is also leaving its mark on amblyopia therapy. New media and technologies can be used both in the actual amblyopia therapy or therapy monitoring. In particular in this review shutter glasses, therapy monitoring and analysis using microsensors and newer video programs for amblyopia therapy are presented and critically discussed. Currently, these cannot yet replace classic amblyopia therapy. They represent interesting options that will occupy us even more in the future.


Assuntos
Ambliopia , Ambliopia/diagnóstico , Ambliopia/terapia , Óculos , Humanos , Internet , Rotação , Privação Sensorial
4.
J Med Internet Res ; 22(10): e21299, 2020 10 06.
Artigo em Inglês | MEDLINE | ID: mdl-33001828

RESUMO

BACKGROUND: A large number of web-based COVID-19 symptom checkers and chatbots have been developed; however, anecdotal evidence suggests that their conclusions are highly variable. To our knowledge, no study has evaluated the accuracy of COVID-19 symptom checkers in a statistically rigorous manner. OBJECTIVE: The aim of this study is to evaluate and compare the diagnostic accuracies of web-based COVID-19 symptom checkers. METHODS: We identified 10 web-based COVID-19 symptom checkers, all of which were included in the study. We evaluated the COVID-19 symptom checkers by assessing 50 COVID-19 case reports alongside 410 non-COVID-19 control cases. A bootstrapping method was used to counter the unbalanced sample sizes and obtain confidence intervals (CIs). Results are reported as sensitivity, specificity, F1 score, and Matthews correlation coefficient (MCC). RESULTS: The classification task between COVID-19-positive and COVID-19-negative for "high risk" cases among the 460 test cases yielded (sorted by F1 score): Symptoma (F1=0.92, MCC=0.85), Infermedica (F1=0.80, MCC=0.61), US Centers for Disease Control and Prevention (CDC) (F1=0.71, MCC=0.30), Babylon (F1=0.70, MCC=0.29), Cleveland Clinic (F1=0.40, MCC=0.07), Providence (F1=0.40, MCC=0.05), Apple (F1=0.29, MCC=-0.10), Docyet (F1=0.27, MCC=0.29), Ada (F1=0.24, MCC=0.27) and Your.MD (F1=0.24, MCC=0.27). For "high risk" and "medium risk" combined the performance was: Symptoma (F1=0.91, MCC=0.83) Infermedica (F1=0.80, MCC=0.61), Cleveland Clinic (F1=0.76, MCC=0.47), Providence (F1=0.75, MCC=0.45), Your.MD (F1=0.72, MCC=0.33), CDC (F1=0.71, MCC=0.30), Babylon (F1=0.70, MCC=0.29), Apple (F1=0.70, MCC=0.25), Ada (F1=0.42, MCC=0.03), and Docyet (F1=0.27, MCC=0.29). CONCLUSIONS: We found that the number of correctly assessed COVID-19 and control cases varies considerably between symptom checkers, with different symptom checkers showing different strengths with respect to sensitivity and specificity. A good balance between sensitivity and specificity was only achieved by two symptom checkers.


Assuntos
Infecções por Coronavirus/diagnóstico , Infecções por Coronavirus/epidemiologia , Autoavaliação Diagnóstica , Internet , Pneumonia Viral/diagnóstico , Pneumonia Viral/epidemiologia , Avaliação de Sintomas/instrumentação , Adolescente , Adulto , Algoritmos , Betacoronavirus , Centers for Disease Control and Prevention, U.S. , Técnicas de Laboratório Clínico , Coleta de Dados , Humanos , Pessoa de Meia-Idade , Pandemias , Valor Preditivo dos Testes , Informática em Saúde Pública , Reprodutibilidade dos Testes , Autorrelato , Sensibilidade e Especificidade , Estados Unidos , Adulto Jovem
5.
Psychiatr Danub ; 32(Suppl 2): 269-272, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32970646

RESUMO

INTRODUCTION: Bullying is an aggressive, intentional act carried out by a group or an individual repeatedly and over time against a victim who cannot easily defend himself or herself. However, with the advent of electronic communication via the internet and mobile phones has led to appearence of a new form of violence, i.e. cyberbullying. Cyberbullying is define as "willful and repeated harm inflicted through computer, cell phones and other electronic device". The aim of this paper is to point to the growing problem of cyberbullying. METHODS: Review the research and theoretical literature. RESULTS: Bullying through the Internet tends to occur at a later age, around 14 years, when children spend more time on their mobile phones and social networking sites. Estimates indicate that between 15% and 35% of young people have been victims of cyberbullying and between 10% and 20% of individuals admit to having cyberbullied others. Perpetrators of cyberbullying have a degree of anonymity not possible in traditional bullying, and the potential exposure and embarrassment of the victim is on a larger scale. It is possible to victimize a peer within their own home or elsewhere at any time of day or night, and should they remove themselves from the site, the messages often accumulate. Victims of bullying often have mental health problems, including depressive symptomatology, self-harm and suicidal behaviors. CONCLUSIONS: This presents new challenges for individuals, families, schools, professionals, researchers, and policy makers.


Assuntos
Cyberbullying/estatística & dados numéricos , Vítimas de Crime/psicologia , Vítimas de Crime/estatística & dados numéricos , Humanos , Internet , Ideação Suicida
6.
Am J Orthod Dentofacial Orthop ; 158(4): 612-620, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32988569

RESUMO

INTRODUCTION: The evaluation of online information regarding orthodontic temporary anchorage devices (TADs) is lacking despite the increase in their use by orthodontists. This cross-sectional study aimed to investigate the quality of information regarding TADs available on the Internet to the general public. METHODS: Two search terms ("orthodontic temporary anchorage device" and "orthodontic miniscrew") were entered separately into a total of 5 search engines. The DISCERN instrument, Journal of the American Medical Association (JAMA) benchmarks, and Health on the Net Foundation Code of Conduct were used to evaluate the quality of information contained within Web sites that satisfied the inclusion and/or exclusion criteria. Web site readability was assessed via the Simple Measure of Gobbledygook and Flesch Reading Ease Score tools. Descriptive statistical analyses and Cohen's kappa intrarater reliability tests were performed. RESULTS: Thirty-one Web sites were evaluated. Most were authored by orthodontists (77.4%) and originated from the U.S. (38.7%). The mean (standard deviation [SD]) DISCERN score was 41.87 (8.45) out of 80, with a range of 27-57. Intrarater reliability testing for DISCERN scores was excellent (0.84). Four Web sites achieved all 4 JAMA benchmarks, and 2 achieved none. Referencing of content sources throughout the Web sites scored least via DISCERN (mean 1.49 out of 5 per Web site [SD, 0.77]) and JAMA (19.35% of Web sites). One Web site contained the Health on the Net Foundation Code of Conduct seal. The mean (SD) Simple Measure of Gobbledygook score was 8.75 (1.25), with a range of 6.5-11.3. The mean (SD) Flesch Reading Ease Score was 59.81 (7.17), with a range of 47.6-73.8. CONCLUSIONS: The quality of information related to TADs on the Internet is moderate. The usefulness of the information may be further reduced because it was beyond the readability of the average member of the general public. Web site authors should consider the use of additional expertise, quality of information tools, and readability formulas to ensure high-quality and easily readable content.


Assuntos
Informação de Saúde ao Consumidor , Estudos Transversais , Internet , Reprodutibilidade dos Testes , Ferramenta de Busca , Estados Unidos
7.
J Pastoral Care Counsel ; 74(3): 212-213, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32967544

RESUMO

In this article, the author from Rochester General Hospital reflects on COVID impact: "Communication has sometimes suffered cold and automated relationship outcomes but there are oases in this dessert." Personal signals in a public world are humanizing artifacts in a new sterile and hypercontrolled virtual reality.


Assuntos
Telefone Celular , Infecções por Coronavirus/epidemiologia , Internet , Relações Interpessoais , Assistência Religiosa , Pneumonia Viral/epidemiologia , Betacoronavirus , Humanos , Pandemias
8.
J Nepal Health Res Counc ; 18(2): 316-319, 2020 Sep 08.
Artigo em Inglês | MEDLINE | ID: mdl-32969401

RESUMO

Online learning has been in a rising trend across the world due to increasing technology in education. Corona Virus Disease 2019 (COVID-19) pandemic enforced all the academic institutions to start online classes for the students. But the students' readiness for the adoption of online learning remains unknown. Hence, this study aimed to assess the readiness of online classes among students. Descriptive cross-sectional web based survey was carried out among 704 students who have enrolled in various streams of Bachelor level programs in Chitwan Medical College. The finding of this study revealed that 87.1% of students from various faculties were ready for online classes during COVID pandemic and 88.8% had internet facility in their home setting. Furthermore, this study found that readiness for online classes was significantly higher among female than male students (89.7% vs.83.5%, p=0.016) and students who had internet accessibility in their residence than those who did not have it (83.8% vs.34.2%, p=<0.001) but there was no significant association between readiness for online classes with academic programs (p=0.062) and years (p=0.905). Therefore, online learning can be considered as a viable alternative method in the academic institutions for the students. Keywords: COVID-19 Pandemic; online classes; readiness; students.


Assuntos
Infecções por Coronavirus/epidemiologia , Educação a Distância/métodos , Educação de Graduação em Medicina/métodos , Internet , Pneumonia Viral/epidemiologia , Estudantes de Medicina/psicologia , Betacoronavirus , Estudos Transversais , Feminino , Humanos , Masculino , Nepal/epidemiologia , Pandemias , Inquéritos e Questionários , Adulto Jovem
9.
J Headache Pain ; 21(1): 115, 2020 Sep 24.
Artigo em Inglês | MEDLINE | ID: mdl-32972360

RESUMO

BACKGROUND: Since the declaration COVID-19 as a pandemic, healthcare systems around the world have faced a huge challenge in managing patients with chronic diseases. Patients with migraine were specifically vulnerable to inadequate medical care. We aimed to investigate the "real-world" impact of COVID-19 pandemic on migraine patients, and to identify risk factors for poor outcome. METHODS: We administered an online, self-reported survey that included demographic, migraine-related, COVID-19-specific and overall psychosocial variables between July 15 and July 30, 2020. We recruited a sample of patients with migraine from headache clinic registry and via social media to complete an anonymous survey. Outcomes included demographic variables, change in migraine frequency and severity during the lockdown period, communication with treating physician, compliance to migraine treatment, difficulty in getting medications, medication overuse, symptoms of anxiety and/or depression, sleep and eating habits disturbance, screen time exposure, work during pandemic, use of traditional medicine, effect of Botox injection cancellation, and overall worries and concerns during pandemic. RESULTS: A total of 1018 patients completed the survey. Of the respondents, 859 (84.3%) were females; 733 (71.9%) were aged 20 to 40 years, 630 (61.8%) were married, and 466 (45.7%) reported working during the pandemic. In comparison to pre-pandemic period, 607 respondents (59.6%) reported increase in migraine frequency, 163 (16%) reported decrease in frequency, and 105 (10.3%) transformed to chronic migraine. Severity was reported to increase by 653 (64.1%) respondents. The majority of respondents; 626 (61.5%) did not communicate with their neurologists, 477 (46.9%) reported compliance to treatment, and 597 (58.7%) reported overuse of analgesics. Botox injections cancellation had a negative impact on 150 respondents (66.1%) from those receiving it. Forty-one respondents (4%) were infected with COVID-19; 26 (63.4%) reported worsening of their headaches amid infection period. Sleep disturbance was reported by 794 (78.1%) of respondents, and 809 (79.5%) reported having symptoms of anxiety and/or depression. CONCLUSIONS AND RELEVANCE: COVID-19 pandemic had an overall negative impact on patients with migraine. Several risk factors for poor outcome were identified. Long-term strategies should be validated and implemented to deliver quality care for patients with migraine, with emphasis on psychosocial well-being.


Assuntos
Infecções por Coronavirus/epidemiologia , Transtornos de Enxaqueca/fisiopatologia , Pneumonia Viral/epidemiologia , Uso Excessivo de Medicamentos Prescritos/estatística & dados numéricos , Adulto , Analgésicos/uso terapêutico , Ansiedade/psicologia , Betacoronavirus , Toxinas Botulínicas Tipo A/uso terapêutico , Comunicação , Depressão/psicologia , Feminino , Acesso aos Serviços de Saúde , Humanos , Internet , Kuweit/epidemiologia , Masculino , Pessoa de Meia-Idade , Transtornos de Enxaqueca/tratamento farmacológico , Transtornos de Enxaqueca/prevenção & controle , Transtornos de Enxaqueca/psicologia , Fármacos Neuromusculares/uso terapêutico , Pandemias , Relações Médico-Paciente , Fatores de Risco , Sono , Distúrbios do Início e da Manutenção do Sono/fisiopatologia , Distúrbios do Início e da Manutenção do Sono/psicologia , Inquéritos e Questionários , Adulto Jovem
12.
F1000Res ; 9: 570, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32884676

RESUMO

The 2019-2020 global pandemic has been caused by a disease called coronavirus disease 2019 (COVID-19). This disease has been caused by the Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2). By April 30 2020, the World Health Organization reported 3,096,626 cases and 217,896 deaths, which implies an exponential growth for infection and deaths worldwide. Currently, there are various computer-based approaches that present COVID-19 data through different types of charts, which is very useful to recognise its behavior and trends. Nevertheless, such approaches do not allow for observation of any projection regarding confirmed cases and deaths, which would be useful to understand the trends of COVID-19. In this work, we have designed and developed an online dashboard that presents actual information about COVID-19. Furthermore, based on this information, we have designed a mathematical model in order to make projections about the evolution of cases and deaths worldwide and by country.


Assuntos
Infecções por Coronavirus/mortalidade , Análise de Dados , Pneumonia Viral/mortalidade , Software , Betacoronavirus , Humanos , Internet , Modelos Teóricos , Pandemias
13.
Psychiatr Danub ; 32(Suppl 1): 79-82, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32890368

RESUMO

In the last decades internet has transformed our way to communicate, relate and work. Probably it has already changed also the way of thinking, perceiving ourselves and reality. The increasing web-based social networking services is a striking feature of modern human society. Internet represents the real, extraordinary novelty of the third millennium and a large part of humanity is already online. Therefore, it can be postulated that the mind on the Internet will produce events and changes that we cannot ignore.


Assuntos
Internet , Mídias Sociais , Rede Social , Humanos
14.
Rev Lat Am Enfermagem ; 28: e3361, 2020 Sep 07.
Artigo em Inglês, Espanhol, Português | MEDLINE | ID: mdl-32901773

RESUMO

OBJECTIVE: amidst the greatest health crisis in history triggered by COVID-19, this documental study was intended to understand the meanings individuals who have lost loved ones in this context assign to the phenomenon of suppressed funeral rituals. METHOD: based on the theory of grief, the corpus of this study was composed of documents published in digital media containing personal writings and reports of experiences freely and easily available to the public. Two researchers with expertise in the field used inductive thematic analysis to interpret data. RESULTS: the experiences shared in the reports reflect the suffering experienced by the sudden death of a significant person, which is amplified by the absence or impediment to performing familial farewell rituals. The suppression or abbreviation of funeral rituals is a traumatic experience because family members are prevented from fulfilling their last homage to the loved one who has suddenly passed away, causing feelings of disbelief and indignation. CONCLUSION: alternatives and new ways to celebrate passage rituals in emergencies of strong social commotion such as a pandemic are needed to provide support and comfort to family members, friends, and relatives. These rituals help survivors to overcome the critical moment, decreasing the risk of developing complicated grief.


Assuntos
Luto , Infecções por Coronavirus/psicologia , Rituais Fúnebres , Pneumonia Viral/psicologia , Betacoronavirus , Humanos , Internet , Pandemias
15.
S Afr Med J ; 110(6): 532-536, 2020 May 29.
Artigo em Inglês | MEDLINE | ID: mdl-32880567

RESUMO

BACKGROUND: Institutions are increasingly using technology to augment the class learning experience of medical students. Especially in Africa, local content is key to allow insights and knowledge to emerge and build transformative capacity for students and patients. There is currently no peer-reviewed video content produced by students with the aim of providing education on orthopaedic topics for medical students and patients in this region. OBJECTIVES: To evaluate the demographic and geographical viewership as well as video-specific statistics of orthopaedic teaching videos for medical students on a YouTube channel, with the expressed aim of informing future content production. METHODS: Videos were produced by South African (SA) medical students as a problem-based collaborative project. Student-owned smartphones and various types of free video editing software were used to produce these videos, which were then assessed by a group of orthopaedic specialists and uploaded onto a YouTube channel (UCTeach). The analytical reports of this channel generated by Google and YouTube were analysed regarding watch time per day (minutes), average view duration (minutes), most watched videos, top geographies, age and gender. RESULTS: A total of 83 videos were uploaded to the UCTeach Ortho channel during a 2-year period, with a total watch time of 857 062 minutes and 337 983 views. The majority of viewers were between the ages of 18 and 34 years (85%). India had the most views (n=69 089), followed by the USA (n=66 257) and SA (n=21 882). Most of the videos were watched on mobile phones (n=183 299) and computers (n=128 228). The most watched video, produced in April 2016, was on physiological and pathological gait, with 51 314 views. CONCLUSIONS: Our study provides proof of concept for a new educational material creation and dissemination strategy. A low-cost local collaborative orthopaedic video project by medical students for medical students can lead to high view counts and watch time on YouTube. It is accessible to audiences in low-, middle- and high-income countries. The students' educational videos also reached a global audience consistently over a 3-year period.


Assuntos
Educação de Graduação em Medicina/métodos , Internet , Ortopedia/educação , Gravação em Vídeo , África Austral , Avaliação Educacional , Feminino , Humanos , Masculino , Adulto Jovem
17.
JCO Clin Cancer Inform ; 4: 794-798, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32897736

RESUMO

PURPOSE: COVID-19 is a rapidly emerging worldwide pandemic that has drastically changed health care across the United States. Oncology patients are especially vulnerable. Novel point-of-care resources may be useful to rapidly disseminate peer-reviewed information from oncology experts nationwide. We describe our initial experience with distributing this information through a private, curated, virtual collaboration question-and-answer (Q&A) platform for oncologists. METHODS: The Q&A database was queried for a 2-month period from March 12 to May 12, 2020. We collected the total number of views and unique viewers for the questions. We classified the questions according to their emphasis (practice management, clinical management, both) and disease type across radiation oncology, medical oncology, gynecologic oncology, and pediatric oncology. RESULTS: Seventy-nine questions were approved, 67 of which were answered and generated 49,494 views with 5,148 unique viewers. Most discussions covered clinical management, with breast cancer being the most active disease site. Ten questions covered pediatric oncology and gynecologic oncology. Forty-seven percent of the 11,010 users of the platform visited the website during the 2-month period. CONCLUSION: Discussions on the Q&A platform reached a substantial number of oncologists throughout the nation and may help oncologists to modify their treatment in real time with the rapidly evolving COVID-19 pandemic.


Assuntos
Infecções por Coronavirus , Prova Pericial , Disseminação de Informação , Oncologia , Neoplasias/terapia , Pandemias , Pneumonia Viral , Administração da Prática Médica , Betacoronavirus , Humanos , Internet , Oncologistas , Sistemas Automatizados de Assistência Junto ao Leito
18.
J Med Internet Res ; 22(9): e22181, 2020 09 21.
Artigo em Inglês | MEDLINE | ID: mdl-32924951

RESUMO

BACKGROUND: Real-time global mental health surveillance is urgently needed for tracking the long-term impact of the COVID-19 pandemic. OBJECTIVE: This study aimed to use Google Trends data to investigate the impact of the pandemic on global mental health by analyzing three keywords indicative of mental distress: "insomnia," "depression," and "suicide." METHODS: We examined increases in search queries for 19 countries. Significant increases were defined as the actual daily search value (from March 20 to April 19, 2020) being higher than the 95% CIs of the forecast from the 3-month baseline via ARIMA (autoregressive integrated moving average) modeling. We examined the correlation between increases in COVID-19-related deaths and the number of days with significant increases in search volumes for insomnia, depression, and suicide across multiple nations. RESULTS: The countries with the greatest increases in searches for insomnia were Iran, Spain, the United States, and Italy; these countries exhibited a significant increase in insomnia searches on more than 10 of the 31 days observed. The number of COVID-19-related deaths was positively correlated to the number of days with an increase in searches for insomnia in the 19 countries (ρ=0.64, P=.003). By contrast, there was no significant correlation between the number of deaths and increases in searches for depression (ρ=-0.12, P=.63) or suicide (ρ=-0.07, P=.79). CONCLUSIONS: Our analysis suggests that insomnia could be a part of routine mental health screening during the COVID-19 pandemic.


Assuntos
Infecções por Coronavirus/epidemiologia , Saúde Global/estatística & dados numéricos , Internacionalidade , Internet/estatística & dados numéricos , Saúde Mental/estatística & dados numéricos , Pandemias , Pneumonia Viral/epidemiologia , Ferramenta de Busca/estatística & dados numéricos , Distúrbios do Início e da Manutenção do Sono/epidemiologia , Betacoronavirus , Depressão/epidemiologia , Humanos , Estudos Longitudinais , Suicídio/estatística & dados numéricos
19.
BMC Med Res Methodol ; 20(1): 235, 2020 09 21.
Artigo em Inglês | MEDLINE | ID: mdl-32958001

RESUMO

BACKGROUND: Data analysis and visualization is an essential tool for exploring and communicating findings in medical research, especially in epidemiological surveillance. RESULTS: Data on COVID-19 diagnosed cases and mortality, from January 1st, 2020, onwards is collected automatically from the European Centre for Disease Prevention and Control (ECDC). We have developed a Shiny application for data visualization and analysis of several indicators to follow the SARS-CoV-2 epidemic using ECDC data. A country-specific tool for basic epidemiological surveillance, in an interactive and user-friendly manner. The available analyses cover time trends and projections, attack rate, population fatality rate, case fatality rate, and basic reproduction number. CONCLUSIONS: The COVID19-World online web application systematically produces daily updated country-specific data visualization and analysis of the SARS-CoV-2 epidemic worldwide. The application may help for a better understanding of the SARS-CoV-2 epidemic worldwide.


Assuntos
Betacoronavirus/isolamento & purificação , Biologia Computacional/estatística & dados numéricos , Infecções por Coronavirus/epidemiologia , Visualização de Dados , Pandemias , Pneumonia Viral/epidemiologia , Algoritmos , Betacoronavirus/fisiologia , Biologia Computacional/métodos , Infecções por Coronavirus/transmissão , Infecções por Coronavirus/virologia , Europa (Continente)/epidemiologia , Saúde Global/estatística & dados numéricos , Humanos , Incidência , Internet , Pneumonia Viral/transmissão , Pneumonia Viral/virologia , Vigilância da População/métodos
20.
PLoS One ; 15(9): e0239695, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32970753

RESUMO

Wuhan, China was the epicenter of the 2019 coronavirus outbreak. As a designated hospital for COVID-19, Wuhan Pulmonary Hospital has received over 700 COVID-19 patients. With the COVID-19 becoming a pandemic all over the world, we aim to share our epidemiological and clinical findings with the global community. We studied 340 confirmed COVID-19 patients with clear clinical outcomes from Wuhan Pulmonary Hospital, including 310 discharged cases and 30 death cases. We analyzed their demographic, epidemiological, clinical and laboratory data and implemented our findings into an interactive, free access web application to evaluate COVID-19 patient's severity level. Our results show that baseline T cell subsets results differed significantly between the discharged cases and the death cases in Mann Whitney U test: Total T cells (p < 0.001), Helper T cells (p <0.001), Suppressor T cells (p <0.001), and TH/TSC (Helper/Suppressor ratio, p<0.001). Multivariate logistic regression model with death or discharge as the outcome resulted in the following significant predictors: age (OR 1.05, 95% CI, 1.00 to 1.10), underlying disease status (OR 3.42, 95% CI, 1.30 to 9.95), Helper T cells on the log scale (OR 0.22, 95% CI, 0.12 to 0.40), and TH/TSC on the log scale (OR 4.80, 95% CI, 2.12 to 11.86). The AUC for the logistic regression model is 0.90 (95% CI, 0.84 to 0.95), suggesting the model has a very good predictive power. Our findings suggest that while age and underlying diseases are known risk factors for poor prognosis, patients with a less damaged immune system at the time of hospitalization had higher chance of recovery. Close monitoring of the T cell subsets might provide valuable information of the patient's condition change during the treatment process. Our web visualization application can be used as a supplementary tool for the evaluation.


Assuntos
Infecções por Coronavirus/diagnóstico , Infecções por Coronavirus/mortalidade , Pneumonia Viral/diagnóstico , Pneumonia Viral/mortalidade , Índice de Gravidade de Doença , Subpopulações de Linfócitos T/citologia , Adulto , Idoso , Betacoronavirus , China , Humanos , Internet , Modelos Logísticos , Pessoa de Meia-Idade , Pandemias , Alta do Paciente , Fatores de Risco , Centros de Atenção Terciária
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