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1.
Medicine (Baltimore) ; 100(47): e27948, 2021 Nov 24.
Artigo em Inglês | MEDLINE | ID: mdl-34964775

RESUMO

ABSTRACT: South Korean studies on coronavirus disease-2019 (COVID-19) treatment have described the use of community treatment centers (CTCs), which combine elements of the home and hospital, to isolate and treat mild COVID-19 patients. While the number of South Koreans diagnosed with COVID-19 cases has varied greatly by season, the number of confirmed cases in foreign nationals has shown no seasonality, with an average of around 25 to 30 per day. For foreign patients, accommodation arrangements and travel routes may be difficult; they may also have difficulty accessing medical care, so require careful management.We discuss our experience in operating and managing a CTC for foreign COVID-19 patients arriving in South Korea with mild symptoms. We also propose guidelines for efficient use of resources with respect to treating these patients in CTCs.We present the clinical findings of patients treated at the CTC between 7 October and 22 November 2020, and make some recommendations. We quarantined and treated foreign patients with mild symptoms of COVID-19 at the Ansan CTC. Discharge is determined based on clinical symptoms rather than polymerase chain reaction results. Medical and administrative staff use building A, while building B is used for isolating patients. Medical rounds are in the form of twice-daily video calls. Three kinds of foods with medication are served according to the patient's country of origin.In total, 315 patients were admitted to the Ansan CTC between 7 October and 22 November 2020; 145 of them were discharged from the CTC and 26 were transferred to other hospitals.To utilize medical resources efficiently during the pandemic, it is desirable to reserve CTCs exclusively for foreign patients.


Assuntos
COVID-19 , Centros Comunitários de Saúde/organização & administração , Pandemias/prevenção & controle , Isolamento de Pacientes/métodos , Transferência de Pacientes , Telemedicina/métodos , Humanos , Quarentena/métodos , República da Coreia , SARS-CoV-2
2.
PLoS One ; 16(12): e0261381, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34962952

RESUMO

The Covid-19 pandemic has brought forth a major landscape shock in the mobility sector. Due to its recentness, researchers have just started studying and understanding the implications of this crisis on mobility. We contribute by combining mobility data from various sources to bring a novel angle to understanding mobility patterns during Covid-19. The goal is to expose relations between mobility and Covid-19 variables and understand them by using our data. This is crucial information for governments to understand and address the underlying root causes of the impact.


Assuntos
COVID-19/economia , COVID-19/prevenção & controle , Marketing/estatística & dados numéricos , Pandemias/economia , Pandemias/prevenção & controle , Isolamento de Pacientes/métodos , SARS-CoV-2 , Viagem/estatística & dados numéricos , COVID-19/epidemiologia , COVID-19/mortalidade , Humanos , Países Baixos/epidemiologia
3.
Saudi Med J ; 42(10): 1095-1102, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34611004

RESUMO

OBJECTIVES: To evaluate the impact of home isolation on feelings and behaviors of children aged 6-14 years during COVID-19 pandemic in Tabuk, Saudi Arabia. METHODS: A cross-sectional study was conducted between June and August 2020 in Tabuk, Saudi Arabia. A snowball sampling was applied, parents with children aged 6-14 years participated in this survey (N=361). questionnaires were distributed electronically. RESULTS: Four out of ten children reported severe psychological impact on feelings (41.3%), while a majority of the children demonstrated mild psychological impact on behavior (74.8%). Age was associated with risk of psychological impact on behavior (OR: 7.24, 95% CI: 1.35-16.18). Being male was associated with risk of psychological impact on feelings (OR: 2.38, 95% CI: 0.67-6.43), and behavior (OR: 3.50, 95% CI: 0.42-6.00). Living in a small house or without an outside play area was associated with risk of psychological impact on feelings and behaviors. CONCLUSION: This study revealed that children experienced mild-to-severe psychological impact on behaviors and feelings during home isolation during COVID-19 pandemic. Priority should be given to boys, older age, children of low-income families, living in small houses and those without outside play areas.


Assuntos
COVID-19 , Pandemias , Idoso , Criança , Estudos Transversais , Humanos , Masculino , Isolamento de Pacientes , SARS-CoV-2 , Arábia Saudita/epidemiologia
4.
Acta Med Indones ; 53(3): 349-351, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34611076

RESUMO

COVID-19 is a disease reported to suppress cellular immunity. This may lead to the development of opportunistic infections, among others black fungus, or mucormycosis. On the other hand, pre-existing defect in immunity may render patients susceptible to both mucormycosis and COVID-19. Mucormycosis is a relatively rare fungal infection with rapid progression unless diagnosed promptly and treated adequately, and urgent surgical and medical intervention is lifesaving. The manifestation of mucormycosis largely depends on the presence of exposure to the pathogen and the existing risk factor of the host. As black fungus is locally invasive, the majority of cases will involve tissue damage with local destruction and contiguous spread to nearby structure. We here with present a case of black fungus complicated with COVID-19 in a man with underlying non-Hodgkin's lymphoma.


Assuntos
COVID-19 , Linfoma não Hodgkin , Mucorales/isolamento & purificação , Mucormicose , Septo Nasal/patologia , SARS-CoV-2/isolamento & purificação , Adulto , Biópsia/métodos , COVID-19/complicações , COVID-19/diagnóstico , COVID-19/fisiopatologia , COVID-19/terapia , Desbridamento/métodos , Progressão da Doença , Humanos , Linfoma não Hodgkin/complicações , Linfoma não Hodgkin/patologia , Linfoma não Hodgkin/fisiopatologia , Masculino , Mucormicose/complicações , Mucormicose/microbiologia , Mucormicose/patologia , Mucormicose/fisiopatologia , Doenças Nasais/microbiologia , Doenças Nasais/patologia , Isolamento de Pacientes/métodos , Tempo para o Tratamento , Tomografia Computadorizada por Raios X/métodos
5.
Int J Hematol ; 114(6): 709-718, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34669154

RESUMO

Polymerase chain reaction (PCR) tests cannot always detect the SARS-CoV-2 virus, possibly due to differences in sensitivity between sample types. Under these circumstances, immunochromatography may serve as an alternative method to detect anti-SARS-CoV-2 IgG antibodies that indicate a history of infection. In our analysis of patients with severe COVID-19 infection, we found that 14 of 19 serum samples were positive for IgG antibodies, whereas 6 of 10 samples from patients with asymptomatic or mild cases were negative. Two patients with immune thrombocytopenia who were treated with prednisolone experienced aggressive COVID-19-related respiratory failure and eventually died. Patients not in remission and those who received steroid-based chemotherapy had a higher risk of death, and patients with lymphoid malignancies including lymphoma and myeloma died in larger numbers than those with myeloid malignancies. A stricter cohorting strategy based on repeat PCR tests or isolation to a private room should be adopted in routine care in hematology departments to prevent viral spread to the environment.


Assuntos
COVID-19 , Infecção Hospitalar/prevenção & controle , Doenças Hematológicas/terapia , Anticorpos Antivirais/sangue , Biomarcadores/sangue , COVID-19/complicações , COVID-19/diagnóstico , COVID-19/mortalidade , COVID-19/prevenção & controle , Feminino , Doenças Hematológicas/complicações , Doenças Hematológicas/mortalidade , Humanos , Imunoensaio/métodos , Imunoglobulina G/sangue , Controle de Infecções/métodos , Japão , Masculino , Isolamento de Pacientes , Reação em Cadeia da Polimerase , Risco , SARS-CoV-2/imunologia , Índice de Gravidade de Doença , Taxa de Sobrevida
6.
J Am Psychiatr Nurses Assoc ; 27(5): 355-360, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34651520

RESUMO

INTRODUCTION: In inpatient behavioral health units, a long-standing behavioral management controversy has been whether to physically restrain or seclude patients. The rate of restraint use at the institution underperformed compared with the national average, which led to the project implementation. AIMS: This quality improvement project's objective was to decrease restraint and seclusion use, improve quality of care, and decrease cost through implementation of recovery model principles. METHOD: Implementation started in October 2019 on a 14-bed inpatient medical/geriatric psychiatric unit with 38 psychiatric RNs at a large academic medical center. The project was a pre-post implementation design with interventions consisting of staff education, RN language observation, and orientation toolkit development. Changes in staff knowledge were measured by Recovery Knowledge Inventory surveys at baseline, 1 week posteducation, and 4 months posteducation. Restraint and seclusion use data were analyzed 3 months preimplementation and 3 months postimplementation. RESULTS: Staff knowledge of the recovery model increased from baseline to 1 week postimplementation in all four survey domains (range = 6% to 9% improvement). While improvements were maintained in two survey domains, two domains of staff knowledge showed slight declines (1% to 2% decline in scores) 4 months postintervention. Restraint use decreased 73.1% and seclusion use decreased 16.3% from pre to postintervention. CONCLUSION: Implementation of recovery model principles can decrease restraint and seclusion episodes, which increases quality and decreases cost to the organization.


Assuntos
Transtornos Mentais , Melhoria de Qualidade , Idoso , Hospitais Psiquiátricos , Humanos , Pacientes Internados , Isolamento de Pacientes , Restrição Física
7.
Arch Psychiatr Nurs ; 35(5): 491-498, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34561064

RESUMO

INTRODUCTION: Seclusion still occurs on mental health wards, despite absence of therapeutic efficacy and high risks of adverse patient effects. Literature on the effect of nursing teams, and the role of psychological characteristics in particular, on frequency of seclusion is scarce. AIM: To explore the influence of demographic, professional or psychological, nursing team-level, and shift characteristics on the frequency of use of seclusion. METHODS: Prospective two-year follow-up study. RESULTS: We found that the probability of seclusion was lower when nursing teams with at least 75% males were on duty, compared to female only teams, odds ratio (OR = 0.283; 95% CrI 0.046-0.811). We observed a trend indicating that teams scoring higher on the openness personality dimension secluded less, (OR = 0.636; 95% CrI 0.292-1.156). DISCUSSION: Higher proportions of male nurses in teams on duty were associated with lower likelihood of seclusion. We found an indication that teams with a higher mean openness personality trait tended to seclude less. These findings, if causal, could serve as an incentive to reflect on staff mix if circumstances demand better prevention of seclusion.


Assuntos
Transtornos Mentais , Recursos Humanos de Enfermagem , Feminino , Seguimentos , Humanos , Masculino , Transtornos Mentais/terapia , Saúde Mental , Isolamento de Pacientes , Estudos Prospectivos , Restrição Física
9.
J Infect Dev Ctries ; 15(8): 1074-1079, 2021 08 31.
Artigo em Inglês | MEDLINE | ID: mdl-34516413

RESUMO

INTRODUCTION: Public life in China is gradually returning to normal with strong measures in coronavirus 2019 (COVID-19) control. Because of the long-term effects of COVID-19, medical institutions had to make timely adjustments to control policies and priorities to balance between COVID-19 prevention and daily medical services. METHODOLOGY: The framework for infection prevention and control in the inpatient department was effectively organized at both hospital and department levels. A series of prevention and control strategies was implemented under this leadership: application of rigorous risk assessment and triage before admission through a query list; classifying patients into three risk levels and providing corresponding medical treatment and emergency handling; establishing new ward visiting criteria for visitors; designing procedures for PPE and stockpile management; executing specialized disinfection and medical waste policies. RESULTS: Till June 2020, the bed occupancy had recovered from 20.0% to 88.1%. In total, 13045 patients were received in our hospital, of which 54 and 127 patients were identified as high-risk and medium-risk, respectively, and 2 patients in the high-risk group were eventually laboratory-confirmed with COVID-19. No hospital-acquired infection of COVID-19 has been observed since the emergency appeared. CONCLUSIONS: The strategies ensured early detection and targeted prevention of COVID-19 following the COVID-19 pandemic, which improved the recovery of medical services after the pandemic.


Assuntos
COVID-19/prevenção & controle , Infecção Hospitalar/prevenção & controle , Hospitais/estatística & dados numéricos , Controle de Infecções/métodos , COVID-19/epidemiologia , China/epidemiologia , Infecção Hospitalar/epidemiologia , Infecção Hospitalar/virologia , Hospitalização/estatística & dados numéricos , Hospitais/normas , Humanos , Controle de Infecções/instrumentação , Pacientes Internados/estatística & dados numéricos , Isolamento de Pacientes/métodos , Equipamento de Proteção Individual , Medição de Risco , Triagem
10.
Medicine (Baltimore) ; 100(30): e26720, 2021 Jul 30.
Artigo em Inglês | MEDLINE | ID: mdl-34397706

RESUMO

ABSTRACT: Isolation of confirmed or suspected coronavirus disease 2019 (COVID-19) cases is essential but, as symptoms of COVID-19 are non-specific and test results not immediately available, case identification at admission remains challenging. To inform optimization of triage algorithms, patient flow and patient care, we analyzed characteristics of patients admitted to an isolation ward, both severe acute respiratory syndrome coronavirus 2019 (SARS-CoV-2) positive patients and patients in which initial suspicion was not confirmed after appropriate testing.Data from patients with confirmed or suspected COVID-19 treated in an isolation unit were analyzed retrospectively. Symptoms, comorbidities and clinical findings were analyzed descriptively and associations between patient characteristics and final SARS-CoV-2 status were assessed using univariate regression.Eighty three patients (49 SARS-CoV-2 negative and 34 positive) were included in the final analysis. Of initially suspected COVID-19 cases, 59% proved to be SARS-CoV-2-negative. These patients had more comorbidities (Charlson Comorbidity Index median 5(interquartile range [IQR] 2.5, 7) vs 2.7(IQR 1, 4)), and higher proportion of active malignancy than patients with confirmed COVID-19 (47% vs 15%; P = .004), while immunosuppression was frequent in both patient groups (20% vs 21%; P = .984). Of SARS-CoV-2 negative patients, 31% were diagnosed with non-infectious diseases.A high proportion of patients (59%) triaged to the isolation unit were tested negative for SARS-CoV-2. Of these, many suffered from active malignancy (47%) and were immunosuppressed (20%). Non-infectious diseases were diagnosed in 31%, highlighting the need for appropriate patient flow, timely expert medical care including evaluation for differential diagnostics while providing isolation and ruling out of COVID-19 in these patients with complex underlying diseases.


Assuntos
Teste para COVID-19/métodos , COVID-19/terapia , Isolamento de Pacientes , Idoso , Idoso de 80 Anos ou mais , Viés , COVID-19/diagnóstico , COVID-19/patologia , COVID-19/prevenção & controle , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
11.
Nursing ; 51(8): 56-60, 2021 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-34347756

RESUMO

ABSTRACT: During the COVID-19 pandemic, visitor limitations were implemented in hospitals and long-term-care facilities to prevent transmission of the virus from patients to family members. It is unknown how the context of visitor limitations due to COVID-19 influenced the state of emotions and experiences in family members unable to physically visit their loved ones in person during hospitalization. This article details a study of the perceptions of family members related to being isolated from patients who are hospitalized with confirmed positive COVID-19.


Assuntos
COVID-19/terapia , Família/psicologia , Hospitalização , Isolamento de Pacientes , Ansiedade , COVID-19/virologia , Medo , Feminino , Humanos , Masculino , SARS-CoV-2/isolamento & purificação , Incerteza
12.
Afr J Prim Health Care Fam Med ; 13(1): e1-e10, 2021 Jul 12.
Artigo em Inglês | MEDLINE | ID: mdl-34342477

RESUMO

BACKGROUND: The coronavirus disease 2019 (COVID-19) is an emerging respiratory illness. The World Health Organization declared it a public health emergency of international concern on 30 January 2020 and called for collaborative efforts, such as contact tracing and promoting the public awareness about COVID-19, and recommended prevention and control measures. AIM: The aim of this study was to assess the effect of telephone counselling on the knowledge, attitude and practices (KAPs) of contacts of COVID-19 confirmed cases towards COVID-19 epidemiology and infection prevention and control measures. SETTING: Ten areas in Sharkia Governorate, Egypt divided into six rural and four urban areas. METHODS: A non-randomised controlled trial was conducted in Sharkia Governorate, Egypt, from 26 March 2020 to 12 April 2020 on 208 contacts of confirmed COVID-19 cases, divided equally into two groups: an experiment group that was exposed to telephone counselling by the researchers and a control group that was exposed to routine surveillance by local health authority. A semi-structured questionnaire was used to assess the KAP of both groups towards COVID-19 before and after intervention. RESULTS: After intervention the percent of contacts who achieved good knowledge, positive attitudes and better practice scores in the experimental group was 91.3%, 57.8% and 71.2%, respectively, compared with 13.5%, 7.8% and 16.3%, respectively, in the control group. Male gender and working group were significantly associated with bad practice score. Furthermore, there was a statistically significant positive correlation between differences in knowledge, attitudes and practices of the experimental group before and after the intervention. CONCLUSION: This study proved the effectiveness of telephone counselling in improving COVID-19-related KAP scores of contacts of confirmed COVID-19 cases.


Assuntos
COVID-19/diagnóstico , Busca de Comunicante , Aconselhamento , Conhecimentos, Atitudes e Prática em Saúde , Telefone/estatística & dados numéricos , Adolescente , Adulto , Idoso , COVID-19/psicologia , Estudos Transversais , Egito , Educação em Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Isolamento de Pacientes , População Rural , SARS-CoV-2 , Inquéritos e Questionários , População Urbana , Adulto Jovem
14.
J Occup Environ Hyg ; 18(9): 430-435, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34383620

RESUMO

Personal protective equipment used by healthcare workers to mitigate disease transmission risks while caring for patients with high-consequence infectious diseases can impair normal body cooling mechanisms and exacerbate physiological strain. Symptoms of heat strain (e.g., cognitive impairment, confusion, muscle cramping) are especially harmful in the high-risk environment of high-consequence infectious disease care. In this pilot study, the core body temperatures of healthcare workers were assessed using an ingestible, wireless-transmission thermometer while performing patient care tasks common to a high-level isolation unit setting in powered air purifying respirator (PAPR)-level. The objective was to determine the potential for occupational health hazard due to heat stress in an environmentally controlled unit. Maximum core temperatures of the six participants ranged from 37.4 °C (99.3 °F) to 39.9 °C (103.8°F) during the 4-hr shift; core temperatures of half (n = 3) of the participants exceeded 38.5 °C (101.3 °F), the upper core temperature limit. Future investigations are needed to identify other heat stress risks both in and outside of controlled units. The ongoing COVID-19 pandemic offers unique opportunities for field-based research on risks of heat stress related to personal protective equipment in healthcare workers that can lead to both short- and long-term innovations in this field.


Assuntos
Temperatura Corporal/fisiologia , COVID-19/epidemiologia , Transtornos de Estresse por Calor/etiologia , Isolamento de Pacientes , Equipamento de Proteção Individual/efeitos adversos , Adulto , Índice de Massa Corporal , Feminino , Pessoal de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Saúde do Trabalhador , Pandemias , Projetos Piloto , SARS-CoV-2
15.
BMC Psychiatry ; 21(1): 419, 2021 08 21.
Artigo em Inglês | MEDLINE | ID: mdl-34419009

RESUMO

BACKGROUND: Epidemiological studies have demonstrated considerable differences in the use of coercive measures among psychiatric hospitals; however, the underlying reasons for these differences are largely unclear. We investigated to what extent these differences could be explained by institutional factors. METHODS: Four psychiatric hospitals with identical responsibilities within the mental health care system, but with different inpatient care organizations, participated in this prospective observational study. We included all patients admitted over a period of 24 months who were affected by mechanical restraint, seclusion, or compulsory medication. In addition to the patterns of coercive measures, we investigated the effect of each hospital on the frequency of compulsory medication and the cumulative duration of mechanical restraint and seclusion, using multivariate binary logistic regression. To compare the two outcomes between hospitals, odds ratios (OR) with corresponding 95% confidence intervals (CI) were calculated. RESULTS: Altogether, coercive measures were applied in 1542 cases, corresponding to an overall prevalence of 8%. The frequency and patterns of the modalities of coercive measures were different between hospitals, and the differences could be at least partially related to institutional characteristics. For the two hospitals that had no permanently locked wards, certain findings were particularly noticeable. In one of these hospitals, the probability of receiving compulsory medication was significantly higher compared with the other institutions (OR 1.9, CI 1.1-3.0 for patients < 65 years; OR 8.0, CI 3.1-20.7 for patients ≥65 years); in the other hospital, in patients younger than 65 years, the cumulative duration of restraint and seclusion was significantly longer compared with the other institutions (OR 2.6, CI 1.7-3.9). CONCLUSIONS: The findings are compatible with the hypothesis that more open settings are associated with a more extensive use of coercion. However, due to numerous influencing factors, these results should be interpreted with caution. In view of the relevance of this issue, further research is needed for a deeper understanding of the reasons underlying the differences among hospitals.


Assuntos
Hospitais Psiquiátricos , Transtornos Mentais , Coerção , Humanos , Transtornos Mentais/epidemiologia , Transtornos Mentais/terapia , Isolamento de Pacientes , Restrição Física
18.
Appl Health Econ Health Policy ; 19(5): 709-719, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34312818

RESUMO

INTRODUCTION: Isolation of COVID-19 patients is a vital strategy for preventing the spread of the virus. Isolation without any incentive or compensation for the patients cannot be effective. We sought to find the monetary value of the willingness to accept (WTA) being isolated for COVID-19 in Iran. METHODS: In this discrete choice experiment, scenarios were designed by reviewing the literature and semi-structural interviews. Fourteen choice sets with two scenarios were included in an internet-based questionnaire that was sent to the Telegram Social Network. A total of 617 individuals completed the questionnaire. A random-effects logistic regression model was used for the main analysis. RESULTS: The average monetary value of a WTA 7 days of isolation was US$51.71 (95% confidence interval [CI] 43.09-60.33). The WTA for one day of isolation was US$1.48 (95% CI 1.11-1.85) for unemployed groups, US$1.49 (95% CI 1.18-1.79) for office employees and US$1.36 (95% CI 0.73-2.01) for manual workers. The WTA was 0.44 (95% CI 0.35-0.53) US$ for low-income groups, US$0.68 (95% CI 0.52-0.84) for middle-income groups and US$0.77 (95% CI 0.35-1.18) for high-income groups. CONCLUSIONS: Our findings suggested that financial preferences for being isolated vary widely across individuals within different socioeconomic groups. Policymakers should consider these differences when designing effective intervention to increase compliance with the isolation protocols during infectious disease outbreaks.


Assuntos
COVID-19 , Isolamento de Pacientes/economia , COVID-19/economia , COVID-19/prevenção & controle , Surtos de Doenças/economia , Surtos de Doenças/prevenção & controle , Humanos , Irã (Geográfico)/epidemiologia , Inquéritos e Questionários
19.
Elife ; 102021 07 27.
Artigo em Inglês | MEDLINE | ID: mdl-34311842

RESUMO

Since the start of the COVID-19 pandemic, two mainstream guidelines for defining when to end the isolation of SARS-CoV-2-infected individuals have been in use: the one-size-fits-all approach (i.e. patients are isolated for a fixed number of days) and the personalized approach (i.e. based on repeated testing of isolated patients). We use a mathematical framework to model within-host viral dynamics and test different criteria for ending isolation. By considering a fixed time of 10 days since symptom onset as the criterion for ending isolation, we estimated that the risk of releasing an individual who is still infectious is low (0-6.6%). However, this policy entails lengthy unnecessary isolations (4.8-8.3 days). In contrast, by using a personalized strategy, similar low risks can be reached with shorter prolonged isolations. The obtained findings provide a scientific rationale for policies on ending the isolation of SARS-CoV-2-infected individuals.


Assuntos
COVID-19/epidemiologia , COVID-19/virologia , Isolamento de Pacientes , Guias de Prática Clínica como Assunto , Quarentena , SARS-CoV-2 , COVID-19/diagnóstico , COVID-19/transmissão , Humanos , Modelos Teóricos , Técnicas de Diagnóstico Molecular , Pandemias , Isolamento de Pacientes/métodos , Isolamento de Pacientes/normas , Medicina de Precisão/métodos , Quarentena/métodos , Quarentena/normas , SARS-CoV-2/fisiologia , Carga Viral
20.
PLoS One ; 16(7): e0254012, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34264966

RESUMO

BACKGROUND: In response to the spread of the coronavirus disease 2019 (COVID-19), plenty of control measures were proposed. To assess the impact of current control measures on the number of new case indices 14 countries with the highest confirmed cases, highest mortality rate, and having a close relationship with the outbreak's origin; were selected and analyzed. METHODS: In the study, we analyzed the impact of five control measures, including centralized isolation of all confirmed cases, closure of schools, closure of public areas, closure of cities, and closure of borders of the 14 targeted countries according to their timing; by comparing its absolute effect average, its absolute effect cumulative, and its relative effect average. RESULTS: Our analysis determined that early centralized isolation of all confirmed cases was represented as a core intervention in significantly disrupting the pandemic's spread. This strategy helped in successfully controlling the early stage of the outbreak when the total number of cases were under 100, without the requirement of the closure of cities and public areas, which would impose a negative impact on the society and its economy. However, when the number of cases increased with the apparition of new clusters, coordination between centralized isolation and non-pharmaceutical interventions facilitated control of the crisis efficiently. CONCLUSION: Early centralized isolation of all confirmed cases should be implemented at the time of the first detected infectious case.


Assuntos
COVID-19/prevenção & controle , Isolamento de Pacientes/estatística & dados numéricos , Quarentena/estatística & dados numéricos , COVID-19/transmissão , Notificação de Doenças/estatística & dados numéricos , Transmissão de Doença Infecciosa/estatística & dados numéricos , Humanos , Modelos Estatísticos
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