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1.
Acta Neurochir Suppl ; 127: 11-13, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31407056

RESUMO

In the 1960s Professor Setsuro Ebashi, a physiologist from the University of Tokyo, discovered calcium ion plays a pivotal role in muscle contraction for the first time. However, he was confounded by icy neglect of the society of physiologists. The International Conference on Physiology was held in Boston in 1962, and Dr. Ebashi and his coworker Dr. Anne Mary Weber gave a talk about calcium signal which is a key mechanism for regulating muscle contraction. Every single attendant stood against their theory and even laughed at them.


Assuntos
Contração Muscular , Vasoconstrição , Cálcio , História do Século XX , Humanos , Japão , Masculino , Pesquisa/história
2.
Zootaxa ; 4672(1): zootaxa.4672.1.1, 2019 Sep 20.
Artigo em Inglês | MEDLINE | ID: mdl-31716028

RESUMO

Pugettia quadridens (De Haan, 1837) and its closely similar congener, P. intermedia Sakai, 1938, are redescribed and illustrated and their possible infraspecific variations related to sexual, ontogenetic, and environmental differences are discussed. As a result, a new species, Pugettia ferox, which had long been believed to be a local variant of P. quadridens sensu lato in the northeast Japan, is described. Despite moderate sexual dimorphism and considerable variability related to their ontogeny, the three species can be distinguished from each other by the combination of various morphological characters including the structure of the orbital region and male first gonopods. The patterns of ontogenetic morphological and morphometric changes in the chelipeds, gonopods, and pleons are also differentiated among the three species. The updated distribution ranges of three species greatly overlap in the northeast Asian waters, although P. quadridens sensu stricto is distributed more southward than P. ferox n. sp.. Distinguishing characters between P. quadridens s.s. and P. pellucens Rathbun, 1932, and between P. intermedia and P. vulgaris Ohtsuchi, Kawamura Takeda, 2014, are revised.


Assuntos
Braquiúros , Animais , Japão , Masculino , Caracteres Sexuais
3.
Zootaxa ; 4594(1): zootaxa.4594.1.1, 2019 May 03.
Artigo em Inglês | MEDLINE | ID: mdl-31716068

RESUMO

Ponera is a widespread genus of litter and soil ants. The highest diversity of the genus is found in Asia, with Taiwan and Japan being two of the most species-rich regions. Here, we systematically review the taxonomy of the 16 Taiwanese and Japanese Ponera species, two of which are new species from Taiwan: Ponera terayamai sp. n. and P. wui sp. n. A new key for Ponera species of East Asia is presented.


Assuntos
Formigas , Animais , Ásia , Extremo Oriente , Japão , Taiwan
4.
Zootaxa ; 4590(2): zootaxa.4590.2.2, 2019 Apr 26.
Artigo em Inglês | MEDLINE | ID: mdl-31716092

RESUMO

Character state variation among species within Dendrothrips Uzel is discussed, with seven species-groups suggested based on sculpture of body and fore wing surface. Sexual dimorphism in pronotal sculpture and posteroangular setae is described in D. magnoliae. The major host plants of several species are indicated, and the wide distribution across Asia of some species emphasised. Species of Dendrothrips from China are reviewed, D. octosparsus sp. n. is described from Oleaceae, and a key presented to the ten species from China. Two species previously known only from Japan, D. magnoliae Kudô and D. latimaculatus Nonaka Okajima, are newly recorded from China along with the first description of their males. The male of D. homalii Zhang Tong is described and illustrated. The record from China of D. mendax Bhatti is considered a misidentification of D. latimaculatus. D. schmiae Kudô is synonymized with D. minowai Priesner.


Assuntos
Tisanópteros , Distribuição Animal , Animais , Ásia , China , Japão , Masculino , Caracteres Sexuais
5.
Zootaxa ; 4590(2): zootaxa.4590.2.7, 2019 Apr 26.
Artigo em Inglês | MEDLINE | ID: mdl-31716097

RESUMO

The name, Galathea keijii, was given to a Miocene fossil species of squat lobster from Japan by Karasawa (1993: 39, pl. 6, figs. 1, 2, 3, 10). In the same year, the name, Galathea keijii, was established for a living species from the Andaman Sea and Arabian Sea (Tirmizi Javed 1993: 50, fig. 22). Therefore, both names are homonymous. The description of Karasawa was published in the Bulletin of the Mizunami Fossil Museum, no. 20, which, on the inside back cover states the date of publication as December 25, 1993. The description of Tirmizi Javed was published in "Indian Ocean galatheids (Crustacea: Anomura)" by the Marine Reference Collection and Resource Centre, University of Karachi. This work was published in 1993 but the day and month of publication were not cited in the publication. In the absence of evidence to the contrary, the date of publication for "Indian Ocean galatheids (Crustacea: Anomura)" is deemed to be the last day of 1993, by application of Article 21.3.2 of the International Code of Zoological Nomenclature (ICZN 1999: 20). As such, application of Article 52 on the principle of homonymy of the International Code of Zoological Nomenclature (ICZN, 1999: 56) shows that Galathea keijii Karasawa, 1993, takes precedence over Galathea keijii Tirmizi Javed, 1993. In accordance with Article 60 on the replacement of junior homonyms (ICZN 1999: 62, 63) a new replacement name, Galathea nasimae, is here proposed for Galathea keijii Tirmizi Javed, 1993. It is dedicated to the late Dr. Nasima M. Tirmizi (Marine Reference Collection and Resource Centre, University of Karachi).


Assuntos
Anomuros , Decápodes (Crustáceos) , Animais , Fósseis , Oceano Índico , Japão
6.
Zootaxa ; 4644(1): zootaxa.4644.1.1, 2019 Jul 22.
Artigo em Inglês | MEDLINE | ID: mdl-31717036

RESUMO

Japanese species of the genus Zeugophora Kunze, 1818 (Coleoptera, Megalopodidae, Zeugophorinae) are revised. In this publication, Zeugophora annulata (Baly, 1873), Z. unifasciata (Jacoby, 1885), Z. hozumii Chûjô, 1953, Z. japonica Chûjô, 1951, Z. varipes (Jacoby, 1885), Z. chujoi Ohno, 1961, Z. flavonotata (Chûjô, 1935), and Z. gracilis unicolor Chûjô, 1958 are redescribed, with detailed illustrations of the male and female genitalia. Additionally, Z. nigricollis (Jacoby, 1885) is restored to a valid species from junior synonymy with Z. bicolor (Kraatz, 1879), and Z. cupka sp. nov., is described as a new species.


Assuntos
Besouros , Animais , Feminino , Japão , Masculino
7.
Zootaxa ; 4695(4): zootaxa.4695.4.4, 2019 Nov 11.
Artigo em Inglês | MEDLINE | ID: mdl-31719342

RESUMO

During a survey of deep-sea fauna, using a Remotely Operated Vehicle, a single specimen (21.6 mm in standard length) of Larsonella pumilus (Larson Hoese, 1980) was collected at a depth of 214 m off the coast of Okinawa Island, Japan. It represents the first record of this species from Japan. The collection site was far deeper than previous reports for this species. This suggests that the main habitat of L. pumilus is deeper than previously recognized and it may explain the paucity of records of this species. As the previously available morphological description of L. pumilus was based on only a single specimen (holotype), this new specimen is described herein. Its morphology corresponds closely to the original description of the holotype, except that faint melanophores are arranged radially around the eyes and scattered on the trunk and the fins. Mitochondrial genome sequences of L. pumilus and 19 related species demonstrate close relationships between L. pumilus and the genus Priolepis. These data also indicate that the genus Priolepis is not monophyletic.


Assuntos
Perciformes , Animais , Peixes , Ilhas , Japão , Filogenia
8.
Zootaxa ; 4686(1): zootaxa.4686.1.9, 2019 Oct 14.
Artigo em Inglês | MEDLINE | ID: mdl-31719505

RESUMO

The thysanopteran genus Chiridurothrips Okajima is known from a single extant species, C. hisakoae Okajima, collected in Japan (ThripsWiki 2019). Occurring on dead leaves and branches of evergreen trees in the subtropical Ryukyu Islands, this species remains known from only five females (Okajima 1981, 2006; also pers. comm. 2018). Within Phlaeothripidae, Chiridurothrips is associated with the tribe Plectrothripini. Species of this sub-group feed on fungal hyphae or the break-down products of fungal attack on decaying plant material (Mound Ng 2018). They are found mainly under the bark of trees or on dead branches, and they do not seem to inhabit leaf-litter (Okajima 1981). At present, Plectrothripini comprises 60 extant species in 13 genera, with no fossils recorded. Of these species 32 are placed in the genus Plectrothrips Hood, ten in Streptothrips Priesner, and six in Chirothripoides Bagnall, whereas both Menothrips Hood and Mastigothrips Priesner each include only two species. The remaining eight species are all placed in separate monobasic genera (ThripsWiki 2019). Concerning this strongly asymmetric classification, Mound and Ng (2018) suggest that Plectrothripini might be particularly old, with the large number of monobasic genera each representing a relict lineage. An alternative possibility, however, might be an unusual instability in the genes controlling morphogenetic processes, and thus resulting in striking autapomorphies on which each one of these genera is diagnosed (Mound Ng 2018). Species associated with Plectrothripini share the following character states (Okajima 1981; Mound Tree 2017): antennae 8-segmented, segment II with the campaniform sensillum situated in the basal half, III-IV with stout sense cones, VIII slender with narrow base; head with posterior ocelli close to compound eyes; pronotum commonly with sclerotized plate eroded or reduced, prosternal basantra week or absent; legs with fore tarsal tooth large; mid and hind tibiae commonly with apical spur-like setae; macropterae with fore wings parallel-sided, usually with duplicated cilia; pelta broad at base, abdominal tergite II eroded laterally; abdominal sternites often with reticulate glandular areas. Regarding the fore wings, it seems worth mentioning that in some members of Plectrothripini the subbasal wing vein is reduced and thus the three subbasal wing setae are lacking (see Plectrothrips tenuis Okajima, Chiridurothrips [c.f. fig. 2], Chirothripoides, Lonchothrips Hood; Bhatti 1998; Okajima 1981). This short vein that is present in (almost all) other macropterous Phlaeothripidae has been interpreted as a plesiomorphic feature that resulted from the reduction of a former well-developed longitudinal first vein of ancestral Tubulifera, the Rohrthripidae (Ulitzka 2018, 2019).


Assuntos
Âmbar , Tisanópteros , Animais , República Dominicana , Feminino , Fósseis , Japão
9.
Anticancer Res ; 39(11): 6265-6271, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31704856

RESUMO

BACKGROUND/AIM: The present study aimed to examine the influence of antibiotics (AB) on the clinical outcomes of Japanese patients treated with immune check point inhibitors (ICIs) for metastatic renal cell carcinoma (RCC) patients. PATIENTS AND METHODS: A total of 31 patients with metastatic RCC treated with ICIs from November 2016 to April 2019 were retrospectively reviewed and analyzed. RESULTS: Five patients were treated with AB prior to ICIs treatment. Median progression free survival (PFS) of patients treated with AB vs. patients not treated with AB was 2.8 months and 18.4 months, respectively. The difference between PFS was statistically significant (p=0.0004). In multivariate analyses, AB use (p=0.0377) and presence of immune related adverse events (p=0.0042) were independent prognostic factors for PFS in association with ICIs therapy. CONCLUSION: The use of AB before ICIs treatment was a predictor of poor ICIs response in metastatic RCC.


Assuntos
Antibacterianos/uso terapêutico , Antineoplásicos Imunológicos/uso terapêutico , Carcinoma de Células Renais/tratamento farmacológico , Neoplasias Renais/tratamento farmacológico , Administração Oral , Adulto , Idoso , Idoso de 80 Anos ou mais , Antibacterianos/administração & dosagem , Antineoplásicos Imunológicos/efeitos adversos , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Grupo com Ancestrais do Continente Asiático , Carcinoma de Células Renais/imunologia , Carcinoma de Células Renais/secundário , Feminino , Humanos , Ipilimumab/efeitos adversos , Ipilimumab/uso terapêutico , Japão , Neoplasias Renais/imunologia , Neoplasias Renais/patologia , Masculino , Pessoa de Meia-Idade , Nivolumabe/efeitos adversos , Nivolumabe/uso terapêutico , Prognóstico , Intervalo Livre de Progressão , Estudos Retrospectivos , Resultado do Tratamento
10.
Zootaxa ; 4638(4): zootaxa.4638.4.8, 2019 Jul 18.
Artigo em Inglês | MEDLINE | ID: mdl-31712463

RESUMO

Medinodexia japonica sp. nov. is described from Japan and an adult leaf beetle, Aulacophora nigripennis Motschulsky (Coleoptera: Chrysomelidae), is recorded as its host. A piercing-type ovipositor is one of the characteristics of the genus Medinodexia Townsend, but it is also found in other blondeliine genera. To evaluate the structural differences of the piercing-type ovipositor, the female postabdominal characters were examined within Blondeliini and their phylogenetic implications are briefly discussed. Females of Medinodexia are similar to those of Medina Robineau-Desvoidy for the presence of invaginations on tergite 6 and sternite 6 of the abdomen. Medinodexia exigua Shima and M. orientalis Shima are not treated here, because they are considered to belong to an undescribed genus due to differences in the male and female postabdominal characters distinguishing them from the remaining species of Medinodexia.


Assuntos
Besouros , Dípteros , Animais , Feminino , Japão , Masculino , Filogenia
11.
Zootaxa ; 4638(2): zootaxa.4638.2.6, 2019 Jul 16.
Artigo em Inglês | MEDLINE | ID: mdl-31712478

RESUMO

A new species of the lace bug genus Physatocheila Fieber, 1844 (Hemiptera: Heteroptera: Tingidae), is described from eastern Honshu, Japan under the name of P. nigrintegerrima. A photograph of a living individual is also given. This species is found on the fruits of Hovenia dulcis Thunb. (Rhamnaceae) and is the first documented fruit-feeder of the genus. A key to the species of the genus from Japan is provided.


Assuntos
Hemípteros , Heterópteros , Distribuição Animal , Animais , Frutas , Japão
12.
Zootaxa ; 4638(1): zootaxa.4638.1.6, 2019 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-31712487

RESUMO

The systematic status of Gelechia acanthopis Meyrick, 1932 is reviewed. The general and functional morphology of the male genitalia merits a new genus in Pexicopiini, Sitotrogoides gen. nov., for G. acanthopis. The musculoskeletal apparatus of the male genitalia in Sitotrogoides is described for the first time and compared with allied genera. The taxonomic position of the genus Sitotrogoides is determined within the tribe Pexicopiini. The lack of the muscle m3 is suggested as a characteristic associating Sitotrogoides with Sitotroga and differing from all other genera in Pexicopiini. The type species of Sitotrogoides, Gelechia acanthopis Meyrick is redescribed. Our new records of Sitotrogoides acanthopis from Korea suggest its extended distribution out of Japan.


Assuntos
Lepidópteros , Mariposas , Distribuição Animal , Estruturas Animais , Animais , Genitália Masculina , Japão , Masculino , Tamanho do Órgão , República da Coreia
13.
Zootaxa ; 4629(2): zootaxa.4629.2.9, 2019 Jul 05.
Artigo em Inglês | MEDLINE | ID: mdl-31712526

RESUMO

A new genus, Stictotettix gen. nov. and two new species of Dikraneurini, S. cleyerae sp. nov. and S. morishimai sp. nov., are described and illustrated, based on the specimens from Japan. This new genus is unique in the male genital features of the aedeagal atrium. The two new species live on pentaphylacacean trees, Cleyera japonica and Eurya japonica, respectively.


Assuntos
Hemípteros , Animais , China , Japão , Masculino , Árvores
14.
Zootaxa ; 4629(1): zootaxa.4629.1.2, 2019 Jul 04.
Artigo em Inglês | MEDLINE | ID: mdl-31712531

RESUMO

Notes are provided for six microcaddisfly species (Trichoptera, Hydroptilidae) in the Japanese fauna. One is a new species, Hydroptila nago Ito sp. nov., described from southern Japan. The second and third, Hydroptila dorsoprocessuata Botosaneanu 1993, previously known from eastern Russia, and Hydroptila introspinata Zhou and Sun 2009, known from northeastern China and Korea, are recorded from Japan for the first time and redescribed. A fourth, Hydroptila parapiculata Yang and Xue 1994, is known from central and southeastern China and central Japan; the male is redescribed. By synonymizing Ugandatrichia shinshiroensis Ito et al. 2018, described from central Japan, with a Chinese species, Allotrichia rhynchophyllum Zhou et al. 2016, we record the genus Allotrichia McLachlan from Japan for the first time. For a sixth species, Stactobia distinguenda Nozaki and Botosaneanu 1996, previously known in Japan from the male only, the larva and its case are described.


Assuntos
Insetos , Distribuição Animal , Animais , China , Japão , Masculino , República da Coreia , Federação Russa
15.
Zootaxa ; 4629(1): zootaxa.4629.1.5, 2019 Jul 04.
Artigo em Inglês | MEDLINE | ID: mdl-31712534

RESUMO

Derisemias tsutsumiuchii sp. nov. and Derisemias kojimai sp. nov. are described from Japan and Taiwan, respectively. These new species are easily distinguished from the known species by positions and sizes of tufts on elytral disc and color pattern of body surface.


Assuntos
Besouros , Distribuição Animal , Animais , Japão , Jordânia , Taiwan
16.
Zootaxa ; 4629(1): zootaxa.4629.1.9, 2019 Jul 04.
Artigo em Inglês | MEDLINE | ID: mdl-31712538

RESUMO

A new species of the anthocorid genus Orius Wolff (subgenus Heterorius Wagner), O. (H.) hibiscus sp. n., is described, based on specimens recently found from the coastal area of Okinawa Island, Ryukyus, Japan. This new species, evidently most related to Orius (Heterorius) strigicollis (Poppius), was found to prefer cryptic habitat, or bract and flower bud of Hibiscus tiliaceus (L.) (Malvaceae) planted at urbanized zones in Naha City. Diagnostic characters of the new species are described, comparing with those of other Japanese members of Heterorius, based on detailed observation using a SEM. An updated checklist and revised key are provided to aid in identification of all known Japanese Orius species.


Assuntos
Hemípteros , Heterópteros , Hibiscus , Malvaceae , Animais , Flores , Japão
17.
Science ; 366(6465): 581-582, 2019 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-31672887
18.
Nihon Shokakibyo Gakkai Zasshi ; 116(11): 913-926, 2019.
Artigo em Japonês | MEDLINE | ID: mdl-31708504

RESUMO

Although chronic constipation is highly prevalent, its definition remains unclear. Therefore, the prevalence varies depending on reports, and the understanding of actual situations is unclear. Hence, we performed an internet survey on constipation among the Japanese general population to study the background factors and actual situations. Preliminary study on the awareness of constipation was conducted among 10000 people in which 9523 of them was asked if they had constipation at the time of the survey. In this population, 51.5% realized that they had constipation. Multivariate analysis showed the significant association of constipation to age, sex, and past histories or complications of diabetes, hemorrhoids, and cerebrovascular diseases. In a main research composed of 3000 general Japanese population, approximately 30.9% of the subjects reported the use of laxatives to treat constipation, and 43.8% of them were found to use irritant laxatives. Moreover, 67.5% of the subjects purchased laxatives at a pharmacy. The frequency of bowel movement less than 3 times per week was manifested in 36.3% of the subjects, and more than once per week in 21.4%. The percentage of hard (Bristol Stool Form Scale [BSFS] Type 1-2), normal (BSFS Type 3-5), and diarrhea stools (BSFS Type 6-7) was 33.1%, 60.0%, and 6.9%, respectively. The quality of life (QOL) of the subjects with hard and diarrhea stools evaluated by SF-8 was significantly lower than that of those with normal stools. Furthermore, the actual monthly cost for the therapeutic drugs used for treating constipation was less than 1000 yen in 75% of the subjects. Analysis of the IBS-QOL-J indicated that the ≥5000 yen payable group had the lowest satisfaction of defecation among the study groups. At present, many Japanese patients with constipation have not been receiving enough treatment for constipation. Therefore, appropriate medication by physicians as well as instruction to patients is required.


Assuntos
Constipação Intestinal/epidemiologia , Qualidade de Vida , Humanos , Internet , Japão/epidemiologia , Inquéritos e Questionários
19.
Kyobu Geka ; 72(10): 738-743, 2019 Sep.
Artigo em Japonês | MEDLINE | ID: mdl-31582687

RESUMO

Impella, a newly developed microaxial blood pump, has been used as a less invasive left ventricular assist device in more than 800 case in the last 18 months since its approval in Japan. Our experiences in 26 patients indicated that it improved not only cardiac output, but also cardiac function, which resulted in cardiac recovery in 16 patients. In this article technical knack and pitfalls including vascular approach and catheter manipulation during implantation, exchange, and explantation of Impella were described. Cardiovascular surgeons who know the detail of the techniques may play a crucial role in successful less invasive mechanical circulatory support for cardiogenic shock patients.


Assuntos
Coração Auxiliar , Cirurgiões , Humanos , Japão , Choque Cardiogênico , Resultado do Tratamento
20.
Kyobu Geka ; 72(10): 781-788, 2019 Sep.
Artigo em Japonês | MEDLINE | ID: mdl-31582696

RESUMO

In coronary artery bypass grafting, graft harvesting is a fundamental and important technique of cardiovascular surgeons. Young cardiovascular surgeons typically experience graft harvesting for the first time early in their training. While several methods for graft harvesting have been developed in recent years with the goal of improving graft patency and reducing surgical invasiveness, the conventional and basic procedures remain important and are performed widely in cardiovascular institutions throughout Japan. Becoming familiarized with these basic graft harvest procedures is considered extremely important and useful for young cardiovascular surgeons. In this chapter, we discuss the basic methods of harvesting grafts of the internal thoracic artery, radial artery, gastroepiploic artery, and saphenous vein.


Assuntos
Ponte de Artéria Coronária , Artéria Torácica Interna , Angiografia Coronária , Japão , Veia Safena , Grau de Desobstrução Vascular
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