Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 2.408
Filtrar
3.
J Assoc Physicians India ; 68(3): 14-18, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32138476

RESUMO

Aim: : Appropriate calculation of sample size and choosing the correct sampling technique are of paramount importance to produce studies that are capable of drawing clinically relevant conclusions with generalizability of results. The current study was planned with an objective to determine reporting of sample size and sampling considerations in clinical research articles published in the year 2017. Methods: One high impact factor journal and one low impact factor journal belonging to the specialities of Medicine, Surgery, Obstetrics and Gynaecology, Paediatrics and Pharmacology were selected and checked for adherence to reporting of sample size and sampling considerations. Results: A total of 264 articles were examined. These consisted of 55 interventional studies and 209 observational studies. Interventional studies showed higher reporting of sample size calculation/justification for sample size selection (29.1%) compared to observational studies (14.8%). Only 33 out of 155 articles from high impact factor journals and 14 out of 109 articles from low impact factor journals mentioned about sample size calculation or justified the sample size. In addition to this, merely 68 out of 209 observational studies mentioned about sampling considerations such as sampling technique/participant follow up/matching details. Conclusion: The reporting of sample size and sampling considerations was found to be low in both high impact factor and low impact factor journals. Though interventional studies had better reporting compared to other study designs, the reporting was still not adequate and there is an immense scope for improvement.


Assuntos
Jornalismo Médico , Publicações Periódicas como Assunto , Publicações , Criança , Humanos , Fator de Impacto de Revistas , Obstetrícia , Projetos de Pesquisa , Tamanho da Amostra
4.
PLoS One ; 15(2): e0226143, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32069305

RESUMO

In June 2017, the International Committee of Medical Journal Editors (ICMJE) announced a requirement that authors reporting the results of clinical trials to journals that follow ICMJE recommendations must include an individual participant data (IPD) sharing statement with manuscripts submitted after 01 July 2018. Additionally, all new clinical trials for which enrollment began on or after 01 January 2019 must include a data sharing statement in the trial's publicly posted registration. This study sought to understand whether IPD sharing statements of clinical trials first registered on ClinicalTrials.gov before 01 January 2019 reflected comprehension of the expectations and a willingness to share. To establish baseline characteristics for the prevalence and quality of IPD sharing statements, we examined IPD sharing statements among 2,040 clinical trials first posted on ClinicalTrials.gov between 01 January 2018 and 06 June 2018. Two independent coders further analyzed the quality of the IPD sharing statements of trials whose registration records indicated the intent to share IPD. The vast majority of trials included in this study did not indicate an intent to share IPD (n = 1,928; 94.5%). Among the trials that did commit to sharing IPD (n = 112, 5.5%), significant variability existed in the content and structure of IPD sharing statements. The results of this study suggest that successful compliance with the IPD sharing statement requirements of the ICMJE will require further clarification, enhanced education, and outreach to investigators.


Assuntos
Ensaios Clínicos como Assunto/normas , Políticas Editoriais , Jornalismo Médico/normas , Manuscritos Médicos como Assunto , Escrita Médica/normas , Revelação , Humanos , Disseminação de Informação/métodos
7.
Hist Cienc Saude Manguinhos ; 26(4): 1317-1335, 2019.
Artigo em Português | MEDLINE | ID: mdl-31800844

RESUMO

The objective of this text is to analyze how homeopathy was conveyed to the lay public in Brazil during the 1970s, an important period in the process of legitimizing this practice as a medical specialty, which occurred in 1980. The sources analyzed (composed of articles that circulated in the Jornal do Brasil and books intended for the lay public) allow the reader to distinguish different interlocutors with various expectations of homeopathy, revealing a heterogeneous universe of understandings and uses for this medical system. At the same time, the sources establish a universe of representations present in the construction of homeopathy as alternative medicine, which is noticeable in its relationship with the counterculture movements and New Era in forming a "consuming public" for homeopathy.


Assuntos
Homeopatia/história , Jornalismo Médico/história , Brasil , Terapias Complementares/história , Cultura , História do Século XX , Humanos , Jornais como Assunto/história , Publicações/história
9.
BMC Cancer ; 19(1): 998, 2019 Oct 24.
Artigo em Inglês | MEDLINE | ID: mdl-31651263

RESUMO

BACKGROUND: The low data publication rate for Food and Drug Administration (FDA)-approved drugs, and discrepancies between FDA-submitted versus published data, remain a concern. We investigated the publication statuses of sponsor-submitted clinical trials supporting recent anticancer drugs approved by the FDA, with a focus on immune checkpoint inhibitors (ICPis). METHODS: We identified all ICPis approved between 2011 and 2014, thereby obtaining 3 years of follow-up data. We assessed the clinical trials performed for each drug indication and matched each trial with publications in the literature. The primary benchmark was the publication status 2 years post-approval. We examined the association between time to publication and drug type using a multilevel Cox regression model that was adjusted for clustering within drug indications and individual covariates. RESULTS: Between 2011 and 2014, 36 anticancer drugs including 3 ICPis were newly approved by the FDA. Of 19 trials investigating the 3 ICPis, 11 (58%) were published within 2 years post-approval. We randomly selected 10 of the 33 remaining anticancer drugs; 68 of 101 trials investigating these drugs (67%) were published. Overall, the publication rate was 66% at 2 years post-approval with a median time to publication of 2.3 years. There was no significant difference in the time to trial publication between ICPis and other anticancer drugs (adjusted hazard ratio [HR], 1.1; 95% confidence interval [CI], 0.8-1.7; P = 0.55). However, findings related to non-ICPis investigated specifically in randomized phase 2 or phase 3 trials were significantly more likely to be published earlier than those related to ICPis (adjusted HR, 7.4; 95% CI, 1.8-29.5; P = 0.005). CONCLUSION: One in 3 sponsor-submitted trials of the most recently approved anticancer drugs remained unpublished 2 years post-FDA approval. We found no evidence that the drug type was associated with the time to overall trial publication.


Assuntos
Antineoplásicos/uso terapêutico , Ensaios Clínicos como Assunto , Aprovação de Drogas , Fatores Imunológicos/uso terapêutico , Jornalismo Médico , Neoplasias/tratamento farmacológico , Estudos Epidemiológicos , Seguimentos , Humanos , Modelos Logísticos , Modelos de Riscos Proporcionais , Viés de Publicação , Resultado do Tratamento , Estados Unidos
11.
PLoS One ; 14(9): e0220897, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31513581

RESUMO

Medical experts are one of the main sources used by journalists in reporting on medical science. This study aims to 1) identify problems that medical experts encounter in contacts with the media representatives, 2) elucidate their attitudes about interactions with journalists and 3) reflect on solutions that could improve the quality of medical journalism. By using in-depth interviews, focus groups and a survey directed to 600 medical experts in 21 countries, this cohort study elucidates medical experts' experiences and views on participating in popular media. A strong interest in interacting with the media was identified among the experts, where nearly one fifth of the respondents in the survey claimed that they contacted the media more than 10 times per year. Six obstacles for improving the quality of medical reporting in the media were found: deadlines, headlines, choice of topic or angle, journalist's level of medical knowledge, differences in professional culture and colleagues' opinions. The main concern among experts was that short deadlines and exaggerated headlines could harm journalistic quality. It is possible that this is partly due to ongoing changes in the media landscape with many new platforms and less control functions. Nevertheless, for several reasons many experts have great interest in interacting with the media, something that could contribute to better communication and fewer misunderstandings. Our results highlight factors like expert networks, media training for scientists and regular meetings that may facilitate communication between medical experts and medical reporters.


Assuntos
Comunicação , Meios de Comunicação de Massa , Medicina , Grupos Focais , Humanos , Intenção , Jornalismo Médico , Inquéritos e Questionários
12.
MEDICC Rev ; 21(2-3): 3, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31373577

RESUMO

Rare grand initiatives and discoveries aside, population health and its supporting science usually advance by the slow accretion and sharing of a myriad of capacities, findings and interventions across the global scientific community. In the best of cases, ordinary people benefit. But in the worst cases, science is shunted aside, ignored or twisted to fit interests that actively oppose the right to health.


Assuntos
Jornalismo Médico , Publicações Periódicas como Assunto , Saúde da População , Editoração , Ciência , Cuba , Humanos
14.
Hist Cienc Saude Manguinhos ; 26(2): 556-572, 2019 Jun 19.
Artigo em Espanhol | MEDLINE | ID: mdl-31241675

RESUMO

The goal of this article is to document early attitudes to X-rays in scientific culture in the city of Buenos Aires. Using various types of periodical sources, the text explores the different reactions to the novelty among different actors in the literary world. Newspapers and weekly magazines for the general public quickly broadcast the discovery, stressing its marvelous or prodigious nature. Meanwhile, physicians in the city took contrasting positions, ranging from mistrust to enthusiasm. Lastly, spiritualists in the city wrote numerous texts about the innovation, and reinterpreted it in accordance with their strategies for self-legitimation.


Assuntos
Atitude do Pessoal de Saúde , Jornalismo Médico/história , Opinião Pública/história , Radiografia/história , Raios X , Argentina , História do Século XIX , Humanos , Médicos/história , Espiritualismo/história
15.
Rev. Asoc. Esp. Neuropsiquiatr ; 39(135): 67-90, ene.-jun. 2019.
Artigo em Espanhol | IBECS | ID: ibc-186382

RESUMO

Se realiza un estudio sobre la introducción de la palabra "psiquiatría" en los diccionarios españoles, lo mismo convencionales que especializados en medicina, para conocer de esta forma el posible origen del término, los cambios de acepción que ha experimentado con los años o su tardía presencia en el Diccionario de la Real Academia Española. También se rastrea la presencia de este mismo vocablo en la prensa española de la segunda mitad del siglo XIX, tanto la de carácter político o cultural como la de medicina y ciencias en general. Llama la atención que, aparentemente, el término "psiquiatría" tarda en incorporarse al léxico profesional y al del público en general, pues, aunque aparece por primera vez en una revista médica en 1861, no será hasta la última década del siglo XIX cuando se haga un hueco en la literatura periodística española. Cabe destacar también la frecuencia con la que aparece el término en los textos que tratan sobre la responsabilidad civil de los enfermos mentales


This paper shows the results of a study carried out on the introduction of the word "psychiatry" in Spanish dictionaries, both in conventional ones and in those specialized in medicine. One of the goals of this work is to know the possible origin of the term, the changes of meaning that has experienced over the years and its late presence in the Dictionary of the Royal Spanish Academy. It also traces the presence of this word in the Spanish press of the second half of the nineteenth century, both in the political or cultural press and in the medical and scientific one. There is evidence that it took a long time for the term "psychiatry" to be incorporated into the professional and general vocabulary. In 1861, the word "psychiatry" appeared for the first time in a medical journal, but it was not until the last decade of the nineteenth century that it was commonly found in the Spanish journalistic literature. We would like to emphasize the frequency with which it shows up in texts about civil responsibilities of people with mental disorders


Assuntos
Humanos , História do Século XIX , Percepção Social , Psiquiatria/história , Pessoas Mentalmente Doentes/história , Jornalismo Médico/história , Formação de Conceito , História do Século XX , Responsabilidade Social , Dicionários como Assunto , 50135 , Terminologia como Assunto
17.
Rev Med Chil ; 147(2): 238-242, 2019 Feb.
Artigo em Espanhol | MEDLINE | ID: mdl-31095173

RESUMO

Young authors may benefit by some advices on how to proceed when they decide to write a manuscript and submit it to a medical journal. They should start by selecting the journal considering the topic and nature of their study, how relevant the results seem and the interest it may have in editors and readers. A reasonable choice should consider new journals that publish good papers selected after external peer review. Then they should study and follow the Instructions to Authors of the chosen journal. A strong call is given to recognize and avoid "predatory journals". Specific statements refer to Instructions to Authors and language requirements by the journal, the need to follow "ICMJE Recommendations", the correct assignment of authorship, and a strict observance of ethical regulations in biomedical and clinical research. Special mention is given to provide a good abstract, in English, either descriptive or structured depending on the nature of their study. These advices may be useful as well as a reminder to older authors on how to improve their manuscripts before submitting them to a mainstream medical journal.


Assuntos
Autoria/normas , Jornalismo Médico/normas , Editoração/normas , Manuscritos Médicos como Assunto , Editoração/ética , Redação/normas
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA