Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 1.184
Filtrar
1.
Acta Vet Scand ; 62(1): 48, 2020 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-32887621

RESUMO

BACKGROUND: Microbiological examination of lesions found in slaughtered animals during meat inspection is an important part of public health protection as such lesions may be due to zoonotic agents that can be transmitted by meat. Examination of inflamed lymph nodes also plays a particular important role, as lymphadenitis may reflect a more widespread infection. Such lesions in sheep are mainly caused by pyogenic bacteria but also mycobacteria are occasionally found. Meat inspection data from 2017 to 2018 from southern Poland, especially from the Malopolska region, indicate that purulent or caseous lymphadenitis involving the mediastinal and tracheobronchial lymph nodes (MTLNs) is a common finding. The primary aim of the current study was to determine the aetiology of these lesions. Furthermore, it was investigated how presence of lesions was correlated with age and grazing strategy of affected sheep. RESULTS: Post-mortem examination revealed purulent or caseous lymphadenitis in the MTLNs of 49 out of 284 animals (17.3%). Subsequent microbiological examination revealed the presence of Corynebacterium pseudotuberculosis (34.7%), Streptococcus dysgalactiae subsp. equisimilis (34.7%), Staphylococcus aureus (8.2%), Enterococcus spp. (2.0%), Trueperella pyogenes (2.0%), and ß-haemolytic strains of Escherichia coli (2.0%). Mycobacterium spp. and Rhodococcus equi were not detected. In older sheep, the probability of the presence of purulent or caseous lymphadenitis was higher than in younger, and the risk was increasing by 1.5% with each month of life. Sheep grazing locally had 4.5-times greater risk of having purulent or caseous lymphadenitis than individuals summer grazing in the mountains. CONCLUSION: The most common aetiological agents of purulent or caseous lymphadenitis in the MTLNs of sheep in the Malopolska region were C. pseudotuberculosis and S. dysgalactiae subsp. equisimilis. Particular attention during post-mortem examination should be paid to the carcasses of older sheep and sheep grazing on permanent pastures, as they seem more prone to develop purulent or caseous lymphadenitis.


Assuntos
Infecções Bacterianas/veterinária , Inspeção de Alimentos , Microbiologia de Alimentos , Linfonodos/patologia , Linfadenite/veterinária , Carne/microbiologia , Doenças dos Ovinos/epidemiologia , Matadouros , Fatores Etários , Criação de Animais Domésticos/métodos , Animais , Infecções Bacterianas/epidemiologia , Infecções Bacterianas/microbiologia , Infecções Bacterianas/patologia , Linfonodos/microbiologia , Linfadenite/epidemiologia , Linfadenite/microbiologia , Linfadenite/patologia , Polônia , Ovinos , Doenças dos Ovinos/microbiologia , Doenças dos Ovinos/patologia , Carneiro Doméstico
2.
Am J Clin Pathol ; 154(2): 215-224, 2020 07 07.
Artigo em Inglês | MEDLINE | ID: mdl-32367142

RESUMO

OBJECTIVES: Kikuchi-Fujimoto disease (KFD) and systemic lupus erythematosus (SLE) are benign entities with histologic features that raise concern about malignancy and infection. We searched for a histology-independent KFD/SLE signature relying on only immunophenotype and basic clinical characteristics. METHODS: A histology-independent KFD/SLE signature was generated using 975 excised lymph nodes with flow immunophenotyping, including 16 cases of KFD/SLE. This signature was then evaluated in 1,198 fine-needle aspiration (FNA) specimens. RESULTS: The top flow cytometry discriminant for KFD/SLE was uniform CD38+ expression on CD19+ events. Immunohistochemistry demonstrated nodules of IgD+, IgM- B cells surrounding necrotizing and activated T-cell areas. A signature combining 6 flow cytometry criteria with age and sample site had a positive predictive value of 88% for KFD/SLE, which had a prevalence of 1.6%. All 4 signature-positive FNA cases with follow-up excision were KFD/SLE. At a second institution, 4 of 5 KFD/SLE cases passed the top discriminant. CONCLUSIONS: A flow cytometry signature combined with age and biopsy site identifies KFD/SLE independent of histology, suggesting a shared immune composition and independently confirming that KFD/SLE represents a distinct entity. Unexpectedly, an IgD+CD38+ small B-cell population is a distinctive feature of KFD/SLE, suggesting a possible pathologic role for anergic/autoreactive B cells.


Assuntos
Linfadenite Histiocítica Necrosante/diagnóstico , Lúpus Eritematoso Sistêmico/patologia , Linfonodos/patologia , Linfadenite/diagnóstico , Linfadenopatia/diagnóstico , Adolescente , Adulto , Criança , Pré-Escolar , Feminino , Citometria de Fluxo , Linfadenite Histiocítica Necrosante/patologia , Humanos , Imunofenotipagem , Linfadenite/patologia , Linfadenopatia/patologia , Masculino
3.
Vet Radiol Ultrasound ; 61(1): E6-E11, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29544023

RESUMO

A 2-year-old Boer doe was presented with respiratory distress and severe inspiratory dyspnea. Cervical and thoracic radiographs revealed a marked retropharyngeal soft tissue mass effect, several mineralized pharyngeal and retropharyngeal structures, and a pulmonary mass. Computed tomography (CT) revealed a severely enlarged right medial retropharyngeal lymph node, which caused laryngeal compression, leading to upper airway obstruction. Multiple cervical and thoracic lymph nodes, and the pulmonary mass had an irregular layered/laminated pattern of mineralization. Imaging findings were consistent with caseous lymphadenitis, and further confirmed with culture, necropsy, and histopathology. This is the first report of CT appearance of caseous lymphadenitis in a goat.


Assuntos
Doenças das Cabras/diagnóstico por imagem , Linfadenite/veterinária , Animais , Feminino , Doenças das Cabras/patologia , Cabras , Linfadenite/diagnóstico por imagem , Linfadenite/patologia , Radiografia/veterinária , Tomografia Computadorizada por Raios X/veterinária
5.
Am J Trop Med Hyg ; 101(5): 1066-1069, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31549614

RESUMO

Disseminated nontuberculous mycobacterial (NTM) infections usually occur in severely immunosuppressed patients. These infections may also occur in previously immunocompetent patients with acquired anti-interferon-gamma antibodies (anti-IFN-γ Abs). A previously healthy 33-year-old man presented with a 3-week history of cough and fever. Chest computed tomography showed air-space consolidation in the middle lobe of the right lung and enlargement of the supraclavicular, mediastinal, and hilar lymph nodes. Tissue samples obtained via mediastinoscopy showed granuloma formation with acid-fast bacteria; cultures from the tissue revealed Mycobacterium kansasii. Accordingly, a diagnosis of disseminated M. kansasii disease was made. The positive control tested negative in the QuantiFERON-TB Gold In-tube test, suggesting the presence of anti-IFN-γ Abs. The ELISA test for anti-IFN-γ Abs demonstrated an increased titer. Antimycobacterial drug treatments were initiated after diagnosis. His symptoms improved over 2 months, and he remains well on outpatient management. Disseminated M. kansasii disease is a very rare condition suggestive of immunosuppression. Testing for anti-IFN-γ antibodies might be important in all cases of disseminated M. kansasii disease.


Assuntos
Autoanticorpos/imunologia , Hospedeiro Imunocomprometido , Interferon gama/imunologia , Linfadenite/microbiologia , Infecções por Mycobacterium não Tuberculosas/microbiologia , Mycobacterium kansasii/isolamento & purificação , Adulto , Humanos , Linfadenite/patologia , Masculino , Infecções por Mycobacterium não Tuberculosas/diagnóstico
7.
Diagn Microbiol Infect Dis ; 95(3): 114858, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31358343

RESUMO

Seven weeks after being kicked in the face by a cow, a 34-year-old male patient developed a posttraumatic mycobacterial lymphadenitis. A rapidly growing mycobacterial isolate cultured from a surgically drained lymphadenitis pus specimen was identified as Mycobacterium smegmatis by matrix-assisted laser desorption/ionization mass spectrometry and a combination of ITS-, hsp65-, and 16S rRNA-DNA sequence analysis, but as Mycobacterium fortuitum complex using the commercial INNO-LiPA Mycobacteria v2 line probe assay. As it is unclear if the misidentification of this strain is an exception, more research is required.


Assuntos
Linfadenite/diagnóstico , Técnicas de Diagnóstico Molecular/métodos , Infecções por Mycobacterium não Tuberculosas/diagnóstico , Mycobacterium fortuitum/classificação , Mycobacterium fortuitum/genética , Mycobacterium smegmatis/classificação , Mycobacterium smegmatis/genética , Adulto , Animais , Bovinos , Erros de Diagnóstico , Humanos , Linfadenite/microbiologia , Linfadenite/patologia , Linfadenite/terapia , Masculino , Testes de Sensibilidade Microbiana , Técnicas de Diagnóstico Molecular/normas , Infecções por Mycobacterium não Tuberculosas/microbiologia , Infecções por Mycobacterium não Tuberculosas/patologia , Infecções por Mycobacterium não Tuberculosas/cirurgia , Mycobacterium fortuitum/química , Mycobacterium smegmatis/química , Kit de Reagentes para Diagnóstico , Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz , Resultado do Tratamento
8.
Clin Immunol ; 207: 40-42, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31301515

RESUMO

Mutations in MYD88 cause susceptibility to invasive bacterial infections through impaired signaling downstream of toll-like receptors (TLRs) and IL-1 receptors. We studied a patient presenting with neutropenia, delayed umbilical cord separation, BCG adenitis, andP. aeruginosapneumonia. Next-generation DNA sequencing identified a novel homozygous truncation mutation in MYD88 that abolishes MyD88 expression. The patient's dermal fibroblasts had severely impaired IL-6 production after stimulation with ligands for the MyD88-dependent receptors TLR2, TLR4 and IL-1R, while responses to ligands for the MyD88-independent receptors TLR3 and TNF-α were preserved. Notably, secretion of TNF-α, which is essential for BCG control, was also impaired after LPS stimulation. In this first report of BCG infection in MyD88 deficiency, data suggest that MyD88-dependent TNF-α production contributes to control of mycobacterial disease.


Assuntos
Vacina BCG/efeitos adversos , Linfadenite/patologia , Fator 88 de Diferenciação Mieloide/genética , Neutropenia/genética , Pneumonia Bacteriana/microbiologia , Cordão Umbilical/patologia , Vacina BCG/imunologia , Predisposição Genética para Doença , Humanos , Masculino , Neutropenia/patologia , Infecções por Pseudomonas/microbiologia , Pseudomonas aeruginosa
9.
Vet Rec ; 185(2): 54, 2019 07 13.
Artigo em Inglês | MEDLINE | ID: mdl-31175223

RESUMO

Alternative postmortem inspection procedures for the detection of gross abnormalities due to Caseous Lymphadenitis (CLA) of sheep and goats were compared quantitatively against the current Australian Standard (AS4696). Studies on sheep and goats in Australia during 2016 addressed data gaps regarding current prevalence, combinations of multiple lesions within affected carcases and sensitivity of inspection procedures enabling a comparison of alternative with current procedures. Using these contemporary inspection data from 54 915 sheep and 48 577 goats a desktop study estimated the effect of implementing alternative procedures of reduced palpation from eleven carcase sites to the four sites most commonly affected. Under current procedures it was estimated that 86 sheep and 34 goat carcases with CLA lesions are missed per 10,000 carcases. Under alternative procedures it is estimated that an additional 48.4 sheep and 10.5 goat carcases with CLA lesions would be missed per 10 000 carcases. Of these, 38.2 sheep and 5.6 goat per 10 000 carcases would contain CLA only in routinely discarded, non-edible tissue sites. Hence, only an additional 10.2 sheep and 4.9 goat carcases per 10 000 inspected, with CLA in edible tissue sites are estimated to be missed. These alternative procedures have now been officially implemented in the Australian domestic standard.


Assuntos
Matadouros , Infecções por Corynebacterium/veterinária , Inspeção de Alimentos/métodos , Doenças das Cabras/epidemiologia , Linfadenite/veterinária , Doenças dos Ovinos/epidemiologia , Animais , Austrália/epidemiologia , Infecções por Corynebacterium/epidemiologia , Infecções por Corynebacterium/microbiologia , Infecções por Corynebacterium/patologia , Corynebacterium pseudotuberculosis/fisiologia , Doenças das Cabras/microbiologia , Doenças das Cabras/patologia , Cabras , Linfadenite/epidemiologia , Linfadenite/microbiologia , Linfadenite/patologia , Prevalência , Sensibilidade e Especificidade , Ovinos , Doenças dos Ovinos/microbiologia , Doenças dos Ovinos/patologia
13.
BMJ Case Rep ; 12(2)2019 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-30709892

RESUMO

A 8-year-old Irish ethnicity girl presented with 3 days of fever with right-sided neck swelling which was first thought as acute tonsillitis with right-sided lymphadenitis. She was started on intravenous antibiotics. At day 7 of illness, she was diagnosed to have Kawasaki disease with clinical and biochemical evidence. Echocardiogram at day 9 of illness and subsequently CT cardiac angiogram performed revealed giant aneurysm at the right coronary artery with non-obstructing thrombus seen. The patient then commenced on clopidogrel and continued with a regular dose of aspirin. Due to the evidence of thrombus with a giant coronary aneurysm, she was also put on long-term warfarin therapy with regular monitoring of her international normalised ratio to be kept at the range of 2.0-3.0.


Assuntos
Aneurisma Coronário/etiologia , Linfadenite/etiologia , Síndrome de Linfonodos Mucocutâneos/complicações , Trombose/etiologia , Criança , Aneurisma Coronário/diagnóstico , Aneurisma Coronário/patologia , Vasos Coronários/patologia , Diagnóstico Diferencial , Feminino , Humanos , Linfonodos/patologia , Linfadenite/diagnóstico , Linfadenite/patologia , Síndrome de Linfonodos Mucocutâneos/diagnóstico , Síndrome de Linfonodos Mucocutâneos/patologia , Pescoço/patologia , Trombose/diagnóstico , Trombose/patologia , Tonsilite/diagnóstico
15.
World J Urol ; 37(4): 701-708, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30046844

RESUMO

PURPOSE: A significant proportion of patients affected by renal cell carcinoma (RCC) shows a suspicious lymph node involvement (LNI) at preoperative imaging. We sought to evaluate the effect of lymphadenopathies (cN1) on survival in surgical RCC patients with no evidence of LNI at final pathology (pN0). METHODS: 719 patients underwent either radical or partial nephrectomy and lymph node dissection at a single tertiary care referral centre between 1987 and 2015. All patients had pathologically no LNI (pN0). Outcomes of the study were cancer-specific mortality (CSM) and other-cause mortality. Multivariable competing-risks regression models assessed the impact of inflammatory lymphadenopathies (cN1pN0) on mortality rates, after adjustment for clinical and pathological confounders. RESULTS: 114 (16%) and 605 (84%) patients (16%) were cN1pN0 and cN0pN0, respectively. cN1pN0 patients were more frequently diagnosed with larger tumours (8.4 vs. 6.5 cm), higher pathological tumour stage (pT3-4 in 71 vs. 36%), higher Fuhrman grade (G3-G4 in 64 vs. 31%), more frequently with necrosis (75 vs. 44%), and distant metastases (33 vs. 10%) (all p < 0.0001). At univariable analysis, inflammatory lymphadenopathies resulted associated with worse CSM (HR 2.45; p < 0.0001). However, at multivariable analysis, inflammatory lymphadenopathies were not an independent predictor of CSM (HR 0.81; p = 0.4). The presence of metastases at diagnosis was the most important factor affecting CSM (HR 6.54; p < 0.0001). This study is limited by its retrospective nature. CONCLUSIONS: In RCC patients, inflammatory lymphadenopathies (cN1pN0) are associated with unfavourable clinical and pathological characteristics. However, the presence of inflammatory lymphadenopathies does not affect RCC-specific mortality.


Assuntos
Carcinoma de Células Renais/cirurgia , Neoplasias Renais/cirurgia , Excisão de Linfonodo , Linfadenite/patologia , Idoso , Carcinoma de Células Renais/complicações , Carcinoma de Células Renais/mortalidade , Carcinoma de Células Renais/patologia , Causas de Morte , Feminino , Humanos , Inflamação , Neoplasias Renais/complicações , Neoplasias Renais/mortalidade , Neoplasias Renais/patologia , Linfadenite/complicações , Linfadenopatia/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Mortalidade , Nefrectomia , Prognóstico
17.
Tuberk Toraks ; 66(3): 212-216, 2018 Sep.
Artigo em Turco | MEDLINE | ID: mdl-30479228

RESUMO

Introduction: Granulomatous lung disease (GLD) is caused by a wide range of conditions and it is challenge for pulmonologist. A detailed history of exposures is fundamental in GDL and has been found pivotal to reach a precise diagnosis. Materials and Methods: Between September 2014 and December 2016, the distribution of patients diagnosed with granulomatous lymphadenitis in the mediastinal/hilar lymph nodes by endobronchial ultrasound (EBUS) or mediastinoscopy was analyzed. To be listed as 'confident', a diagnosis of sarcoidosis required compatible histological, radiological and clinical findings in conjunction with negative cultures. Infectious entities listed as 'confident' had either microorganisms in tissue section, positive culture, positive serology or positive antigen detection in a consistent clinical pathological setting. Result: Granulomatous lymphadenitis was detected in 110 patients. The included 110 cases consisted of 70.9% women and median age of 53 (range 44-61) years. The final diagnosis of the patients was accepted to be sarcoidosis in 79 (71.8%), sarcoid like granulomas in 7 (6.4%), tuberculosis in 4 (3.6%), silicosis in 4 (3.6%), drug-associated granuloma in 2 (1.8%), hypersensitivity pneumonitis in 1 (0.9%), Chron disease in 1 (0.9%), unspecified in 12 (10.9%). Three patients were classified as tuberculosis based on culture. Conclusions: In this study, we found that the most common cause of granulomatous lymphadenitis was sarcoidosis. Contrary to expectations, the number of patients diagnosed with tuberculosis was very low.


Assuntos
Granuloma/patologia , Linfadenite/patologia , Mediastino/patologia , Adulto , Feminino , Granuloma/complicações , Granuloma/diagnóstico por imagem , Humanos , Linfonodos/patologia , Linfadenite/complicações , Linfadenite/diagnóstico por imagem , Masculino , Mediastino/diagnóstico por imagem , Pessoa de Meia-Idade , Ultrassonografia
18.
J Med Case Rep ; 12(1): 299, 2018 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-30318016

RESUMO

BACKGROUND: Lymphadenopathy is not an uncommon presentation of adult onset Still's disease: it is present in up to two thirds of patients with adult onset Still's disease. The characteristic appearance of lymphadenopathy is described as intense, paracortical immunoblastic hyperplasia. Changes in light microscopy may resemble lymphoma, but immunohistochemistry reveals a benign polyclonal B cell hyperplasia. CASE PRESENTATION: We describe a 67-year-old Sri Lankan woman who manifested relapsing prolonged fever, raised inflammatory markers, arthralgia, myalgia, transient skin rash, and cervical lymphadenopathy histologically characterized by noncaseating granulomatous adenitis with central suppuration. Due to the fact of high prevalence of tuberculosis in the region, an extensive diagnostic evaluation was done to exclude the possibility of extrapulmonary tuberculosis; unsuccessful therapeutic trials of complete antituberculosis regime reliably excluded the possibility of tuberculosis and strengthened the diagnostic validity. Disease flares were characterized by systemic inflammatory response syndrome with immediate clinical and laboratory response to corticosteroids. After systematic diagnostic workup which ruled out possible malignant, rheumatic, or autoimmune diseases and infections previously described as causes of granulomatous adenitis, our patient was diagnosed as having adult onset Still's disease based on Yamaguchi criteria. She required a trial of indomethacin followed by methylprednisolone pulse therapy and long-term maintenance steroid therapy without steroid-sparing immunosuppressive agents or biological disease-modifying antirheumatic drugs. She achieved full disease remission in 3 months. Reevaluation after 6 months and 1 year did not reveal residual disease activity. CONCLUSIONS: To the best of our knowledge this is the first report of suppurative noncaseating granulomatous lymphadenitis attributed to adult onset Still's disease among Asian or South Asian ethnicities and it is also rarely reported among Europeans and North Americans. It is an extremely challenging situation to diagnose Still's disease with granulomatous lymphadenitis where tuberculosis is highly prevalent. This case highlights the importance of consideration of adult onset Still's disease as a potential diagnosis in a compatible clinical context in the presence of noncaseating granulomatous adenitis and indicates that one should not be misled into a diagnosis of tuberculosis by the fact of the high prevalence of tuberculosis, however, the exclusion of other diagnoses is a prerequisite.


Assuntos
Granuloma/complicações , Granuloma/patologia , Linfadenite/complicações , Linfadenite/patologia , Doença de Still de Início Tardio/complicações , Tuberculose , Idoso , Anti-Inflamatórios/uso terapêutico , Anti-Inflamatórios não Esteroides/uso terapêutico , Diagnóstico Diferencial , Feminino , Granuloma/tratamento farmacológico , Humanos , Indometacina/uso terapêutico , Linfadenite/tratamento farmacológico , Metilprednisolona/uso terapêutico , Supuração
19.
Tuberk Toraks ; 66(2): 109-114, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30246653

RESUMO

Introduction: Endobronchial ultrasonography (EBUS) is an endoscopic method that aids needle aspiration to see the bronchial wall and adjacent tissues with an ultrasound probe. Pulmonary arteries are rarely present between the bronchus wall and the tissue. In this case, it was necessary to make a selection between invasive processes and transbronchial needle aspiration (TBNA) through the pulmonary artery. There are few case reports about the safety of TBNA through the pulmonary artery. We aimed to present the results of EBUS guided TBNA through the pulmonary arteries. Materials and Methods: The data on four cases (three men) in whom EBUS guided TBNA was performed through the pulmonary artery between August 2010 and December 2015 were reviewed retrospectively. Procedures were conducted under local anesthesia and conscious sedation. For TBNA, 22-gauge needles were used. Cases were monitored for 24 hour after the procedures. Antibiotic prophylaxis and onsite cytopathology were not used. Result: All lesions existed were on the left hilar localization. Two of the diagnosed cases were carcinoma and one was the granulomatous lymphadenitis. We were not able to diagnose the last case. No complication was observed in any cases during the procedure. Conclusions: EBUS guided TBNA through the pulmonary arteries at left hilar lesions is safe. The rate of diagnoses from the tissues obtained is high. No special preparation is needed for the cases have no the pulmonary hypertension.


Assuntos
Brônquios/diagnóstico por imagem , Broncoscopia/métodos , Aspiração por Agulha Fina Guiada por Ultrassom Endoscópico/métodos , Linfonodos/patologia , Linfadenite/patologia , Artéria Pulmonar/diagnóstico por imagem , Adulto , Idoso , Brônquios/irrigação sanguínea , Feminino , Humanos , Masculino , Mediastino , Pessoa de Meia-Idade , Estudos Retrospectivos
20.
J Laryngol Otol ; 132(9): 827-831, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30180912

RESUMO

BACKGROUND: Although melioidosis in the head and neck region is uncommon, it is a potentially life-threatening infection. Thus, early diagnosis and proper management are very important. OBJECTIVES: To report the clinical presentation and management of melioidosis in the head and neck. METHOD: A retrospective study was conducted from 1 January 2013 to 31 October 2016 in Mukdahan Hospital, Thailand. Case records of patients who had presented with culture-positive melioidosis were analysed. RESULTS: Medical records of 49 patients (23 males and 26 females) were analysed. Patients ranged in age from 1 to 75 years. Clinical presentations included 22 parotid abscesses, 16 neck abscesses and 11 suppurative lymphadenitis cases. Only 35 patients (71 per cent) had high indirect haemagglutination assay titres of ≥ 1:160 (95 per cent confidence interval = 45.35-88.28). Almost half of the patients received intravenous ceftazidime and subsequently oral co-trimoxazole. Oral antibiotic regimens were prescribed for mild localised melioidosis. Overall, 95.65 per cent of patients were in remission and no relapses were observed (95 per cent confidence interval = 85.47-98.80). CONCLUSION: Careful clinical correlation and proper investigation are required to establish an early diagnosis of melioidosis and to initiate appropriate treatment.


Assuntos
Abscesso/microbiologia , Cabeça/microbiologia , Linfadenite/microbiologia , Melioidose/microbiologia , Pescoço/microbiologia , Abscesso/diagnóstico , Abscesso/tratamento farmacológico , Abscesso/patologia , Administração Intravenosa , Administração Oral , Adolescente , Adulto , Idoso , Antibacterianos/uso terapêutico , Burkholderia pseudomallei/isolamento & purificação , Ceftazidima/administração & dosagem , Ceftazidima/uso terapêutico , Criança , Pré-Escolar , Diagnóstico Precoce , Feminino , Cabeça/patologia , Humanos , Lactente , Linfadenite/diagnóstico , Linfadenite/tratamento farmacológico , Linfadenite/patologia , Masculino , Melioidose/diagnóstico , Melioidose/tratamento farmacológico , Melioidose/patologia , Pessoa de Meia-Idade , Pescoço/patologia , Estudos Retrospectivos , Tailândia/epidemiologia , Combinação Trimetoprima e Sulfametoxazol/administração & dosagem , Combinação Trimetoprima e Sulfametoxazol/uso terapêutico , Adulto Jovem
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...