Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 2.491
Filtrar
1.
Isr Med Assoc J ; 22(1): 53-59, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31927807

RESUMO

BACKGROUND: Primary retroperitoneal neoplasms (PRN) arise from diverse retroperitoneal tissues. Soft tissue sarcomas (STS) comprise the majority and are well studied. Other non-sarcomatous PRN are very rare and less familiar. OBJECTIVES: To evaluate the clinicopathologic and radiologic features of non-sarcomatous PRN, as well as the outcome of complete tumor resection (TR). METHODS: Retrospective data were collected on consecutive patients (June 2006 to January 2015) who underwent resection of retroperitoneal lesions at our department. Final pathology of non-sarcomatous PRN was included. RESULTS: The study population included 36 patients (26% with PRN). PRN were neurogenic (17%), fat-containing (3%), and cystic (6%). The preoperative diagnosis was correct in only 28%. All patients underwent TR via laparotomy (72%) or laparoscopy (28%), for mean operative time of 120 ± 46 minutes. En bloc organ resection was performed in 11%. Complete TR was achieved in 97%. Intra-operative spillage occurred in 8%. Intra-operative, 90-day postoperative complications, and mortality rates were 11%, 36%, and 0%, respectively. The mean length of stay was 6.5 ± 5.5 days. The median overall survival was 53 ± 4.9 months. CONCLUSIONS: Familiarity with radiologic characteristics of PRN is important for appropriate management. Counter to STS, other PRN are mostly benign and have an indolent course. Radical surgery is not required, as complete TR confers good prognosis. Expectant management is reserved for small, asymptomatic, benign neoplasms.


Assuntos
Neoplasias Retroperitoneais/diagnóstico , Idoso , Feminino , Ganglioneuroma/diagnóstico , Ganglioneuroma/diagnóstico por imagem , Ganglioneuroma/patologia , Ganglioneuroma/cirurgia , Humanos , Lipoma/diagnóstico , Lipoma/diagnóstico por imagem , Lipoma/patologia , Lipoma/cirurgia , Masculino , Pessoa de Meia-Idade , Neurilemoma/diagnóstico , Neurilemoma/diagnóstico por imagem , Neurilemoma/patologia , Neurilemoma/cirurgia , Neurofibroma/diagnóstico , Neurofibroma/diagnóstico por imagem , Neurofibroma/patologia , Neurofibroma/cirurgia , Paraganglioma/diagnóstico , Paraganglioma/diagnóstico por imagem , Paraganglioma/patologia , Paraganglioma/cirurgia , Neoplasias Retroperitoneais/diagnóstico por imagem , Neoplasias Retroperitoneais/patologia , Neoplasias Retroperitoneais/cirurgia , Estudos Retrospectivos , Tomografia Computadorizada por Raios X
2.
World Neurosurg ; 133: 275-277, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31629145

RESUMO

We report a rare case of cervicothoracic intramedullary and extramedullary lipoma. Complete resection of the extramedullary lipoma and almost complete resection of the intramedullary lipoma were performed using a microscope, followed by posterior fusion and internal fixation from C4-T2 to maintain the stability of the cervicothoracic junction. Despite the high risk, it was still necessary to perform the decompression surgery and the surgical results were favorable.


Assuntos
Vértebras Cervicais/diagnóstico por imagem , Lipoma/diagnóstico por imagem , Neoplasias da Medula Espinal/diagnóstico por imagem , Vértebras Torácicas/diagnóstico por imagem , Adulto , Vértebras Cervicais/cirurgia , Humanos , Laminectomia , Lipoma/cirurgia , Imagem por Ressonância Magnética , Masculino , Neoplasias da Medula Espinal/cirurgia , Fusão Vertebral , Vértebras Torácicas/cirurgia , Resultado do Tratamento
3.
Medicine (Baltimore) ; 98(52): e18434, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31876722

RESUMO

RATIONALE: Although lipomas are the most common benign form of soft tissue tumor in the body, giant lipomas of the hand, defined as >5 cm in diameter, are extremely rare. PATIENT CONCERNS: A 49-year-old man presented with a soft and fixed lump in the left hypothenar area. The mass was not tender, but it was associated with symptoms of tingling sensation and paresthesia in the left ring and little fingers that had lasted for 4 years. DIAGNOSES: Preoperative image studies revealed an encapsulated and multilobulated mass, which measured 8 cm × 5 cm × 2 cm. Basic histologic examination identified the specimen as a lipoma and further immunohistochemical studies ruled out the possibility of malignancy. INTERVENTIONS: To enable a complete excision of the mass, the palmar digital branch of the ulnar nerve for the little finger passing through the mass was temporarily transected. After complete excision of the mass, the branch was coapted again under microscopy. OUTCOMES: Complete sensory recovery was achieved 6 months after surgery, without any sign of recurrence. LESSONS: Although giant lipomas in the hand can extend to vital components such as neurovascular structures, muscles, and tendons, meticulous en bloc resection can provide excellent results without any complications.


Assuntos
Mãos , Lipoma/diagnóstico , Neoplasias de Tecidos Moles/diagnóstico , Mãos/diagnóstico por imagem , Mãos/patologia , Mãos/cirurgia , Humanos , Lipoma/diagnóstico por imagem , Lipoma/patologia , Lipoma/cirurgia , Imagem por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Neoplasias de Tecidos Moles/diagnóstico por imagem , Neoplasias de Tecidos Moles/patologia , Neoplasias de Tecidos Moles/cirurgia , Tomografia Computadorizada por Raios X
5.
Neurocirugía (Soc. Luso-Esp. Neurocir.) ; 30(5): 250-253, sept.-oct. 2019. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-183880

RESUMO

Intradural spinal lipomas with intracranial extension are very rare and are typically diagnosed in childhood. Radical surgical excision usually causes a high rate of morbidity because of the firm adherence between the lipoma and neural tissues. In this report, we present a case of craniocervical intradural intramedullary lipoma in an adult patient. The patient underwent surgery with excision of the mass, leaving a sheet of lipoma on the tumor bed


Los lipomas espinales intradurales con extensión intracraneal son muy raros y suelen diagnosticarse en la infancia. La escisión quirúrgica radical generalmente causa una alta tasa de morbilidad debido a la adherencia firme entre el lipoma y los tejidos neurales. En este artículo, presentamos un caso de lipoma intramedular craneocervical intradural en un paciente adulto. El paciente se sometió a una cirugía con exéresis de la masa, dejando una lámina de lipoma en el lecho tumoral


Assuntos
Humanos , Masculino , Adulto , Neoplasias da Medula Espinal/diagnóstico por imagem , Neoplasias da Medula Espinal/cirurgia , Lipoma/diagnóstico por imagem , Lipoma/cirurgia , Parestesia/complicações , Tomografia , Seio Sagital Superior/diagnóstico por imagem , Seio Sagital Superior/cirurgia
6.
BMJ Case Rep ; 12(8)2019 Aug 13.
Artigo em Inglês | MEDLINE | ID: mdl-31413054

RESUMO

Surgical treatment of lipomas is typically only considered when they are painful or unsightly. We present the case of a massive hip lipoma; with this extreme case, we show that the global prolongation of life expectancy can lead to other indications of removal.


Assuntos
Nádegas , Lipoma/cirurgia , Idoso de 80 Anos ou mais , Diagnóstico Diferencial , Humanos , Lipoma/diagnóstico por imagem , Lipoma/patologia , Masculino , Tomografia Computadorizada por Raios X
8.
J Comput Assist Tomogr ; 43(5): 793-798, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31453977

RESUMO

We present 5 cases of intraosseous hibernoma, a rare benign tumor of brown fat. Our literature review reveals that the average age at presentation is 58.6 years, and 69.7% of patients are female. Lesions are most often located in the spine and pelvis. Computed tomography usually demonstrates sclerotic changes, although lesions can be lytic. Magnetic resonance imaging findings include heterogeneous T2 hyperintensity. Technetium 99m-methyl diphosphonate bone scan reveals variable radiotracer uptake, whereas 18F-labeled fluoro-2-deoxyglucose (FDG) PET-CT shows mild uptake. Intraosseous hibernoma should be considered when imaging demonstrates a fat-containing lesion in bone, especially one exhibiting FDG avidity.


Assuntos
Neoplasias Ósseas/diagnóstico por imagem , Lipoma/diagnóstico por imagem , Idoso , Neoplasias Ósseas/patologia , Diagnóstico Diferencial , Feminino , Fluordesoxiglucose F18 , Humanos , Lipoma/patologia , Imagem por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Tomografia por Emissão de Pósitrons , Compostos Radiofarmacêuticos , Medronato de Tecnécio Tc 99m , Tomografia Computadorizada por Raios X
9.
Int J Pediatr Otorhinolaryngol ; 125: 103-106, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31276891

RESUMO

A 3-year-old female presented for evaluation of progressive snoring since birth. MRI revealed a fatty-appearing mass measuring 2.4 cm × 1.5 cm x 3.0 cm arising from the predental space of C1 and extending anteriorly through the prevertebral space into the retropharyngeal space. The patient underwent endoscopic trans-oral excision of the mass using electrocautery and blunt dissection, and pathological analysis yielded a diagnosis of fibrolipoma. CT imaging twelve months post-surgery showed no recurrence, and the patient remains symptom free two years later. Very few reported cases of nasopharyngeal fibrolipomas exist, and this is the first report of 2-year clinical follow-up.


Assuntos
Fibroma/diagnóstico por imagem , Fibroma/patologia , Lipoma/diagnóstico por imagem , Lipoma/patologia , Neoplasias Nasofaríngeas/diagnóstico por imagem , Neoplasias Nasofaríngeas/patologia , Pré-Escolar , Dissecação , Eletrocoagulação , Feminino , Fibroma/cirurgia , Humanos , Lipoma/cirurgia , Imagem por Ressonância Magnética , Neoplasias Nasofaríngeas/cirurgia , Cirurgia Endoscópica por Orifício Natural , Ronco/etiologia
11.
Indian J Pathol Microbiol ; 62(3): 461-463, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31361241

RESUMO

Hibernoma is a rare, benign soft tissue tumor described in <200 case reports/case series. It is slow-growing, painless, and commonly mistaken for lipoma or liposarcoma. Histopathological diagnosis is must for confirmation. Total excision is the treatment of choice. We present a rare case of hibernoma of thigh, which was initially misdiagnosed as atypical lipomatous tumor/well-differentiated liposarcoma on imaging, which turned out to be a hibernoma on histopathological examination.


Assuntos
Tecido Adiposo Marrom , Erros de Diagnóstico , Lipoma/diagnóstico por imagem , Adulto , Biópsia , Diagnóstico Diferencial , Feminino , Humanos , Lipoma/cirurgia , Lipossarcoma/diagnóstico , Imagem por Ressonância Magnética , Coxa da Perna/patologia , Resultado do Tratamento
15.
J Avian Med Surg ; 33(1): 65-71, 2019 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-31124614

RESUMO

A 9-year-old female rose-breasted cockatoo (Eolophus roseicapilla) was presented for a humeral fracture. At presentation, the bird was severely lethargic and obese. On physical examination, an open right humeral fracture, healed left ulnar fracture, and intertarsal joint swelling were present. Results of hematologic testing and biochemical analysis revealed severe leukocytosis with heterophilia and increased creatine kinase and aspartate aminotransferase activities consistent with musculoskeletal lesions. Radiographs confirmed a right humeral fracture and showed severe polyostotic lytic and expansile lesions of the appendicular skeleton, as well as an enlarged hepatic silhouette. Surgical repair of the fracture was attempted, but the bird died during the procedure. Postmortem examination revealed severe bone deformities involving the fractured humerus, both ulnas, and the left tibiotarsus. Histologic findings were consistent with multiple intraosseous lipomas of the long bones and severe hepatic lipidosis. To our knowledge, this is the first report of multiple intraosseous lipomas in a bird.


Assuntos
Doenças das Aves/diagnóstico por imagem , Neoplasias Ósseas/veterinária , Cacatuas , Fraturas do Úmero/veterinária , Lipoma/veterinária , Animais , Doenças das Aves/patologia , Neoplasias Ósseas/diagnóstico por imagem , Neoplasias Ósseas/patologia , Cacatuas/lesões , Evolução Fatal , Feminino , Fraturas do Úmero/complicações , Lipoma/diagnóstico por imagem , Lipoma/patologia
17.
Pan Afr Med J ; 32: 27, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31143332

RESUMO

Colonic lipomas are uncommon and usually asymptomatic tumors. A 30-year-old woman with abdominal pain lasting 10 days was admitted to the surgical clinic. Her physical examination revealed sensitivity on the right upper quadrant and her bowel sounds were normal. A lesion and invagination findings in the colon were found in the ultrasound examination and CT was performed. CT scan revealed a lipoma and invagination in the colon and the patient has undergone surgery. Pathological diagnosis of the lesion was reported as submucosallipoma. In this case report, we present clinical and radiological findings of a submucosal colonic lipoma causing intussusception.


Assuntos
Neoplasias do Colo/complicações , Intussuscepção/etiologia , Lipoma/complicações , Tomografia Computadorizada por Raios X/métodos , Dor Abdominal/etiologia , Adulto , Doenças do Colo/diagnóstico por imagem , Doenças do Colo/etiologia , Neoplasias do Colo/diagnóstico por imagem , Neoplasias do Colo/cirurgia , Feminino , Humanos , Intussuscepção/diagnóstico por imagem , Lipoma/diagnóstico por imagem , Lipoma/cirurgia
18.
BMC Cancer ; 19(1): 309, 2019 Apr 03.
Artigo em Inglês | MEDLINE | ID: mdl-30943944

RESUMO

BACKGROUND: To evaluate the diagnostic value of MR imaging for the differentiation of lipomas and atypical lipomatous tumors (ALT) in comparison with histology and MDM2 amplification status. METHODS: Patients with well-differentiated lipomatous tumors (n = 113), of which 66 were diagnosed as lipoma (mean age 53 years (range, 13-82); 47% women) and 47 as atypical lipomatous tumor (ALT; mean age 60 years (range, 28-88); 64% women), were included into this study using histology and MDM2 amplification status by fluorescence in situ hybridization (FISH) as standard of reference. Preoperative MR images were retrospectively assessed by two radiologists for the following imaging features: maximum tumor diameter (mm) as well as the affected compartment (intramuscular, intermuscular or subcutaneous), septa (absent, thin (< 2 mm) or thick septa (> 2 mm) with nodular components); contrast enhancing areas within the lipomatous tumor (< 1/3 of the tumor volume, > 1/3 of the tumor volume); RESULTS: Of the 47 patients with ALT, 40 (85.1%) presented thick septa (> 2 mm) and this finding significantly increased the likelihood of ALT (OR 6.24, 95% CI 3.36-11.59; P < 0.001). The likelihood of ALT was increased if the tumor exceeded a maximum diameter of 130.0 mm (OR 2.74, 95% CI 1.82-4.11, P < 0.001). The presence of contrast enhancement in lipomatous tumors significantly increased the likelihood of ALT (Odds ratio (OR) 2.95, 95% confidence interval (CI) 2.01-4.31; P < 0.001). Of the lipomas, 21.1% were located subcutaneously, 63.6% intramuscularly and 15.2% intermuscularly. On the other hand, none of the ALTs were located subcutaneously, the majority was located intermuscularly (87.3%) and a small number of ALTs was located intramuscularly (12.7%). CONCLUSIONS: Our results suggest that using specific morphological MR imaging characteristics (maximum tumor diameter, thick septa and contrast enhancement) and the information on the localization of the lipomatous tumor, a high sensitivity and substantial specificity can be achieved for the diagnosis of lipomas and ALTs.


Assuntos
Amplificação de Genes , Lipoma/diagnóstico por imagem , Lipossarcoma/diagnóstico por imagem , Proteínas Proto-Oncogênicas c-mdm2/genética , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Diagnóstico Diferencial , Feminino , Humanos , Hibridização in Situ Fluorescente , Lipoma/genética , Lipossarcoma/genética , Imagem por Ressonância Magnética/métodos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Sensibilidade e Especificidade , Adulto Jovem
19.
Phys Med ; 60: 76-82, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31000090

RESUMO

BACKGROUND: Subcutaneous fat may have variable signal intensity on T2w images depending on the choice of imaging parameters. However, fatty components within tumors have a different degree of signal dependence on the acquisition scheme. This study examined the use of T2, T2* relaxometry and spin coupling related signal changes (Spin Coupling ratio, SCr) on two different imaging protocols as clinically relevant descriptors of benign and malignant lipomatous tumors. MATERIALS AND METHODS: 20 patients with benign lipomas or liposarcomas of variable histologic grade were examined at an 1.5 T scanner with Multi Echo Spin Echo (MESE) different echo spacing (ESP) in order to produce bright fat T2w images (ESP: 13.4 ms, 25 equidistant echoes) and dark fat images (ESP: 26.8 ms with 10 equidistant echoes). T2* relaxometry acquisition comprises 4 sets of in-opposed echoes (2.4-19.2 ms, ESP: 2.4 ms) Multi Echo Gradient Echo (MEGRE) sequence. All parametric maps were calculated on a pixel basis. RESULTS: Significant differences of SCr were found for five different types of lipomatous tumors (Pairwise t-test with Bonferroni correction): lipomas, well differentiated liposarcomas, myxoid liposarcomas, pleomorphic liposarcomas and poorly differentiated liposarcomas. SCr surpassed the classification performance of T2 and T2* relaxometry. DATA CONCLUSION: A novel biomarker based on spin coupling related signal loss, SCr, is indicative of lipomatous tumor histological grading. We concluded that T2, T2* and SCr can be used for the classification of fat containing tumors, which may be important for biopsy guidance in heterogeneous masses and treatment planning.


Assuntos
Lipoma/diagnóstico por imagem , Lipossarcoma/diagnóstico por imagem , Imagem por Ressonância Magnética/métodos , Biomarcadores Tumorais , Biópsia , Humanos , Lipoma/patologia , Lipossarcoma/patologia , Gradação de Tumores
20.
J Nucl Med Technol ; 47(2): 173-174, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31019037

RESUMO

We report a case of concurrent nodular fasciitis and incidental giant intraperitoneal lipoma diagnosed on whole-body 18F-FDG PET/CT, an imaging modality that has the advantage of being able to detect unsuspected lesions.


Assuntos
Fasciite/complicações , Fluordesoxiglucose F18 , Lipoma/complicações , Lipoma/diagnóstico por imagem , Neoplasias Peritoneais/complicações , Neoplasias Peritoneais/diagnóstico por imagem , Tomografia Computadorizada com Tomografia por Emissão de Pósitrons , Adulto , Feminino , Humanos , Achados Incidentais
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA