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1.
Medicine (Baltimore) ; 99(3): e18770, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-32011467

RESUMO

Discrepancies between clinical and autopsy diagnoses range from 30% to 37%. The significance of deontological examinations remains high. In the pursuit of proper evaluation of diagnostic discrepancies, the establishment of pathogenesis, the mechanism of death, and a correct diagnosis are of particular importance.A retrospective study of deontological examinations, aimed at the detection of medical errors and carried out by the State Forensic Medicine Service during the period 1989 to 2016, was performed. The clinical and autopsy data from 1007 cases were collected in compliance with the research protocol.The number of deontological examinations tends to increase. In 60% of cases, the deceased were men. Most cases were in the age group of 50 to 59 years. Most examinations were carried out in relation to improperly provided healthcare services and the patient's death in surgery, admission, intensive care and obstetrics-gynecology departments. In 13% of cases, the diagnosis did not coincide and, in 79% of cases, the diagnoses fully coincided. In 68% of cases, the medical error was disproved.The number of deontological examinations is increasing. In most cases, clinical and autopsy diagnoses fully matched. Incorrectly clinically diagnosed intracranial injuries were the most common diagnostic mistakes. The data are similar to the results of research in other countries and would be relevant to ensuring the prevention of medical mistakes and the improvement of healthcare quality.


Assuntos
Causas de Morte , Erros de Diagnóstico/estatística & dados numéricos , Medicina Legal/métodos , Erros Médicos/estatística & dados numéricos , Qualidade da Assistência à Saúde/estatística & dados numéricos , Autopsia , Feminino , Humanos , Lituânia , Masculino , Estudos Retrospectivos
3.
Parasit Vectors ; 13(1): 2, 2020 Jan 06.
Artigo em Inglês | MEDLINE | ID: mdl-31907072

RESUMO

BACKGROUND: Birds of the family Laridae have not been intensively examined for infections with Sarcocystis spp. To date, sarcocysts of two species, S. lari and S. wobeseri, have been identified in the muscles of gulls. The aim of the present study was to evaluate the species richness of Sarcocystis in the herring gull, Larus argentatus, from Lithuania. METHODS: In the period between 2013 and 2019, leg muscles of 35 herring gulls were examined for sarcocysts of Sarcocystis spp. Sarcocystis spp. were characterised morphologically based on a light microscopy study. Four sarcocysts isolated from the muscles of each infected bird were subjected to further molecular examination. Sarcocystis species were identified by means of ITS1 sequence analysis. RESULTS: Sarcocysts were detected in 9/35 herring gulls (25.7%). Using light microscopy, one morphological type of sarcocysts was observed. Sarcocysts were microscopic, thread-like, had a smooth and thin (about 1 µm) cyst wall and were filled with banana-shaped bradyzoites. On the basis of ITS1 sequences, four Sarcocystis species, S. columbae, S. halieti, S. lari and S. wobeseri, were identified. Furthermore, it was demonstrated that a single infected herring gull could host two Sarcocystis species indistinguishable under light microscopy. CONCLUSIONS: Larus argentatus is the first bird species found to act as intermediate host of four Sarcocystis spp. According to current knowledge, five species, S. falcatula, S. calchasi, S. wobeseri, S. columbae and S. halieti can use birds belonging to different orders as intermediate hosts.


Assuntos
Doenças das Aves/parasitologia , Sarcocystis/genética , Sarcocistose/veterinária , Animais , Charadriiformes/parasitologia , DNA de Protozoário/genética , Lituânia , RNA Ribossômico 18S/genética , RNA Ribossômico 28S/genética , Sarcocystis/classificação , Sarcocystis/crescimento & desenvolvimento , Sarcocystis/isolamento & purificação , Sarcocistose/parasitologia
4.
Parasitol Res ; 119(2): 687-694, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31897793

RESUMO

Wild rodents, as natural reservoir hosts carrying various species of pathogens, play an important role in the evolution and emergence of zoonotic diseases. In this study, protist parasites, namely Babesia sp., Trypanosoma sp. and Hepatozoon sp. were studied in rodent populations in Lithuania. Two hundred forty rodent specimens of seven species were analysed by a combined approach using polymerase chain reaction (PCR)-based techniques and traditional microscopic examination. The total prevalence of blood parasites reached 35% in rodent communities. The prevalence of Hepatozoon sp. reached the highest value (32%), followed by Trypanosoma sp. (5%) and Babesia sp. (3%). Myodes glareolus and Microtus agrestis were the most heavily infected rodent species. Comparison of microscopy and PCR-based methods showed that the two approaches might give different results and thus can lead to an underestimation of the actual prevalence and abundance of parasites. In our study, PCR-based assays were more sensitive and robust than traditional microscopy. However, precise molecular results for the estimation of the prevalence of Babesia sp. and Hepatozoon sp. were achieved only by using several sets of primers. To avoid inaccurate results, the improvement and detailed description of molecular and microscopy protocols are required.


Assuntos
Arvicolinae/parasitologia , Babesia/isolamento & purificação , Eucoccidiida/isolamento & purificação , Trypanosoma/isolamento & purificação , Animais , Lituânia , Microscopia , Reação em Cadeia da Polimerase
5.
PLoS One ; 15(1): e0227735, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31940412

RESUMO

The paper presents a mapping tool aiming to identify and minimise potential conflicts between onshore wind energy development and wildlife conservation in Lithuania. It merges current information on the distribution, conservation status and sensitivity of birds and bats to wind power with an integrated evaluation of wind resources (modelled wind speed), special planning status and technical perspectives of wind energy development. The paper includes assessment of the selected wildlife species which were described as sensitive to wind power (69 breeding and 43 migratory bird species and 17 bat species bats in the country). Used species level information allowed the precise identification of sensitive territories and might be used to mitigate negative wind farm effects using special measures based on species behavior. Finally, we delivered overlaps as possible conflicts among the most promising wind farm areas and the areas with high sensitivity in relation to bird and bat distribution. These overlaps point to the required attention and relevant decisions that are needed to ensure sustainable development of wind energy throughout the country. We suggest this tool for initial determination of appropriate areas for wind energy development in the country and as supplement to Environmental Impact Assessment.


Assuntos
Distribuição Animal/fisiologia , Conservação dos Recursos Naturais/métodos , Monitorização de Parâmetros Ecológicos/métodos , Desenvolvimento Sustentável , Vento , Animais , Aves/fisiologia , Quirópteros/fisiologia , Lituânia , Modelos Biológicos
6.
Waste Manag ; 102: 441-451, 2020 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-31739278

RESUMO

The objective of this work was to determine the potential of using of solid and liquid digestate, as biofertilizer and soil amendment, and to address adverse unfertile soil erosion problems after analysing areas of potential use. We found a high concentration of organic carbon in a solid fraction of the digestate, which indicates a significant potential for returning carbon to the soil. The influence of digestate fertilization on soil fertility as a function of the amount of available phosphorus (P2O5) and potassium (K2O) in the 0-40 cm layer was found to be very important. The soil fertility category was changed from "high" (200-300 mg kg-1) to "very high" (>300 mg kg-1) according P2O5, using only 170 kg ha-1 of nitrogen in solid and liquid digestate rate. Fertilization with all phases and rates of digestate tend to increase the amount of K2O. The solid digestate fertilization using the 170 kg ha-1 N rate showed a significant increase (5 times) of mineral nitrogen content in the 0-40 cm soil layer. The advantage of solid digestate as a soil improver has been highlighted because it has a positive effect on soil fertility, quality, sustainability and durability. The amount of mobile humic acids (MHA) in eroded loamy Retisol increased 1.6 times in soil 0-40 cm layer with a fertilization rate of 170 kg ha-1 and 1.5 times - of 85 kg ha-1 of solid digestate compared to the untreated. Similar trends of MHA but in lower amount were identified when liquid digestate was applied.


Assuntos
Fertilizantes , Solo , Agricultura , Lituânia , Nitrogênio , Fósforo
7.
Eur J Dent Educ ; 24(2): 227-232, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31845488

RESUMO

AIMS: Efforts to harmonise dental education in Europe have been put into action by the Association for Dental Education in Europe (ADEE). The aim of the study was to explore graduating dentists' perceptions about their professional readiness for clinical work in Finland and Lithuania. MATERIALS AND METHODS: The survey targeted fifth-year dental students at the University of Oulu and the University of Turku in Finland, and at the Lithuanian University of Health Sciences, Kaunas, Lithuania (Lithuanian and international students) in 2016-2017. The competences were evaluated in the questionnaire in 21 dental procedures based on ADEE competences by options: "I'd manage well," "I'd need more training" or "It would not quite succeed." The option "I'd manage well" was chosen in the analyses. RESULTS: Students felt that they were most competent in producing and maintaining accurate patient records (91.9%), implementing sterilisation and hygiene in dental practice (91.3%) and working with other members of dental team and health profession (90.0%). The largest differences between Finnish and Lithuanian students were in designing and adjusting occlusal splints (87.0% vs. 14.3%) and in undertaking subgingival scaling (95.7% vs. 57.1%). The biggest differences between Lithuanian and international students were in identifying (and treating) abnormal and anxiety-related patient (73.1% vs. 25.5%) and implementing tobacco cessation (65.3% vs. 31.9%). CONCLUSIONS: The graduating dental students in Finland and Lithuania manage well in most of the clinical procedures based on the ADEE competences. The students were most confident when dealing with tasks that are common in dental practice.


Assuntos
Odontólogos , Educação em Odontologia , Atitude do Pessoal de Saúde , Europa (Continente) , Finlândia , Humanos , Lituânia , Competência Profissional , Inquéritos e Questionários
8.
Int J Hyg Environ Health ; 223(1): 142-150, 2020 01.
Artigo em Inglês | MEDLINE | ID: mdl-31564508

RESUMO

AIM: The aim of this study was to determine the association between levels of residential surrounding greenness, preschool children's park use, sedentary behaviour, and mental and general health. METHODS: This cross-sectional study included 1489 4-6-year-old children - residents of Kaunas city, Lithuania. Responses to the questionnaires completed by parents were used to ascertain children's general and mental health. We estimated exposure to greenness by the normalised difference vegetation index (NDVI), and time spent in a park (i.e. park use). We used multivariate logistic regression models to explore the independent associations between health outcomes and surrounding greenness and time spent in the nearest city park, controlling for potential confounders. RESULTS: Of all the studied children, 14% had poor perceived general health, and 44.7% spent 5 or more hours per week in city parks. A significant increase in sedentary behaviour was observed in children with poor health. Every additional hour of time spent in parks was associated with decreased sedentary behaviour and a lower risk of poor health; meanwhile, lower residential greenness was associated with poorer mental and general health. Compared with NDVI-100 m > median and park use exceeding 5 h per week, lower greenness exposure and shorter park usage were associated with the risk of poor health (adjusted odds ratio 2.32 (95% CI: 1.43, 3.78) and the general risk of mental difficulties (adjusted odds ratio 1.43 (95% CI: 1.03, 2.18) in 4-6-year-old children. CONCLUSIONS: Lower residential greenness levels and less time spent in a park were associated with poorer general and mental health among 4-6-year-old children. Physical activity in green spaces is recommended as a measure to prevent poor general and mental health among children.


Assuntos
Ambiente Construído , Saúde Mental/estatística & dados numéricos , Parques Recreativos/estatística & dados numéricos , Criança , Pré-Escolar , Cidades , Exposição Ambiental/estatística & dados numéricos , Hábitos , Humanos , Lituânia , Comportamento Sedentário , Inquéritos e Questionários
9.
J Int Adv Otol ; 15(3): 447-453, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31846927

RESUMO

OBJECTIVES: This study aimed to validate the Lithuanian version of the Dizziness Handicap Inventory (DHI-L), investigate its reliability, and perform factor analysis. MATERIALS AND METHODS: A standard protocol of translation was followed for psychometric instruments. A total of 108 patients (75.9% women), mean age 51.9 years, with peripheral or central dizziness and vertigo participated in our cross-sectional study. The internal consistency was measured by Cronbach's alpha coefficient and corrected item-total correlations (CI-TCs). After a week, 65 of the recruited patients were again asked to fill out Dizziness Handicap Inventory (DHI)-L to ascertain test-retest reliability (intraclass correlation, ICC). Concurrent validation was performed using Pearson correlation between the total score and subscales of DHI-L and the eight scales of Short Form-36 Health Survey (SF-36). Finally, the factor structure of the DHI was assessed by principal component analysis (PCA). RESULTS: The Cronbach's alpha coefficient was very high (0.91). CI-TCs for DHI-L total scale ranged from 0.33 to 0.67. The correlations between DHI and SF-36 were high to weak. The ICC was excellent for the total score and its subscales. Our proposed two-factor model explained 44.5% of the variance. The first factor indicated disability in daily activities and psychological effect of handicap. The second factor comprised of items that pertained to postural instability. CONCLUSION: The DHI-L has shown good reliability and validity. Results did not support the original subscale structure of the DHI. As more studies need to be done to restructure DHI, we recommend only using the total DHI score as a measure of dizziness handicap.


Assuntos
Avaliação da Deficiência , Tontura/diagnóstico , Inquéritos e Questionários/normas , Vertigem/diagnóstico , Estudos Transversais , Análise Fatorial , Feminino , Humanos , Lituânia , Masculino , Pessoa de Meia-Idade , Psicometria , Reprodutibilidade dos Testes , Traduções
10.
Medicine (Baltimore) ; 98(46): e17220, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31725600

RESUMO

The purpose of this study was to determine the trends in consumption of antibiotics and evaluate the antibiotic prescription rates in the pediatric population in Lithuania during 2003 to 2012.A cross-sectional study. Data of systemic antibiotic use in pediatric population for outpatient treatment was derived from National Health Insurance Fund database. Consumption was expressed as WHO ATC defined daily dose (DDD)/1000 children/day and as a number of prescriptions written in the general population per year. Statistical analysis was performed using the SPSS/W 20.0 software (Statistical Product and Service Solutions for Windows).Total utilization of antibiotics (expressed in DDD units) during study period increased by 8.40% (from 5.67 to 6.19 DDD/1000 children/day) and by 5.96% expressed in prescription rate (from 585.84 to 622.97 prescriptions/1000 children/year). The most popular antibiotic group was macrolides which showed the highest increase of utilization 5.9 times (from 0.27 DDD/1000 children/day in 2003 to 1.66 DDD/1000 children/day in 2012).The most common indications for antibiotic prescribing for children in 2012 were acute bronchitis (25.6%), acute tonsillitis (21.7%) and acute pharyngitis (14.6%). Amoxicillin had the highest probability to be chosen to treat acute tonsillitis (prob. [probability] = .2875) and acute pharyngitis (prob. = .5553). Clarithromycin had the highest probability to be chosen to treat acute bronchitis (prob. = .4222).Most of the diseases treated with antibiotics were viral infections. The most commonly prescribed antibiotics were broad-spectrum. The consumption of antibiotics was evenly increasing during 2003 to 2012 period, but the distribution of separate antibiotic group remained the same.


Assuntos
Assistência Ambulatorial/tendências , Antibacterianos/uso terapêutico , Uso de Medicamentos/tendências , Vigilância da População , Padrões de Prática Médica/tendências , Criança , Estudos Transversais , Feminino , Humanos , Lituânia/epidemiologia , Masculino
11.
Zootaxa ; 4567(1): zootaxa.4567.1.5, 2019 Mar 14.
Artigo em Inglês | MEDLINE | ID: mdl-31716440

RESUMO

The egg-larvae of 890 individuals in 8 species belonging to long palped crane flies of the genus Tipula (Diptera: Tipulidae) were obtained from 17 gravid females captured in Lithuania in 2011-2012. Depending on the species, it took from four days to more than eleven weeks for the eggs to hatch. Of the four instars of larvae for crane flies, the second, third and the last instar larvae are very similar in morphology, while the first instar or egg-larva differs radically. Descriptions and illustrations of the external morphology, chaetotaxy of abdominal segments, characters of head capsules and last abdominal segments are given for the previously unknown first instar larvae of T. (Lunatipula) fascipennis, T. (Pterelachisus) irrorata, T. (P.) pabulina, T. (P.) pseudovariipennis, T. (Yamatotipula) pruinosa and poorly known T. (Beringotipula) unca, T. (L.) vernalis T. (Tipula) paludosa. The differences of the head capsule and last abdominal segment among the first instar larvae of these species are more obvious than in the last instar. Characters of the head capsule such as the shape of the teeth of the mandible, shape of the basal segment of the antenna and number of sensillae on it, shape of hypostomium, arrangement of sensory structures on the labrum and frons, all differ among egg-larvae of Tipula. Sclerotisation and the arrangement of setae on the spiracular field are unique for each studied Tipula species. This is the first study to use head capsule characters to distinguish the larvae of Tipula.


Assuntos
Dípteros , Animais , Feminino , Larva , Lituânia , Nematóceros , Óvulo
12.
Zootaxa ; 4668(2): zootaxa.4668.2.2, 2019 Sep 10.
Artigo em Inglês | MEDLINE | ID: mdl-31716626

RESUMO

This paper presents the first faunistic review of species composition and distribution of Tetratomidae and Melandryidae (Coleoptera: Tenebrionoidea) in Lithuania. An annotated checklist of the species is given. The peculiarities of some morphological structures of Dircaea australis, Phloiotrya subtilis, Orchesia fusiformis, O. micans and Zilora cf. obscura are briefly reviewed and illustrated. Information on five species of Tetratomidae and twenty-two species of Melandryidae is given, including faunistic data, prior records, general distribution, and notes on frequency, ecology and morphological peculiarities of some species. Eustrophus dermestoides (Tetratomidae), Phloiotrya rufipes, Hypulus bifasciatus and Phryganophilus ruficollis (Melandryidae) known from previous literature records are excluded from the Lithuanian fauna due to suspect data on their occurrence in the country. Phloiotrya subtilis and Orchesia fusiformis are recorded from Lithuania for the first time. The presence of Tetratoma fungorum and Abdera flexuosa in the Lithuanian fauna was confirmed by actual faunistic data, which were previously absent. Four species of Tetratomidae and 19 species of Melandryidae are confidently included in the Lithuanian fauna, corresponding to 50% of the total European fauna of both families excluding regional endemics.


Assuntos
Besouros , Animais , Ecologia , Lituânia
13.
Zootaxa ; 4661(3): zootaxa.4661.3.12, 2019 Aug 29.
Artigo em Inglês | MEDLINE | ID: mdl-31716706

RESUMO

Three species of the extinct Eocene genus Baltostigus (Mastigitae: Baltostigini) were known in Baltic amber from Poland, Lithuania and Russia. In Rovno amber, although it was relatively well-studied, only one Mastigitae genus and species was recorded, belonging to Leptochromini. We report the occurrence of Baltostigus in the area of the present day Ukraine during the Eocene, on the basis of three inclusions in Rovno amber. One specimen belongs to a newly described species, Baltostigus substriatus sp. n.; two specimens are putatively identified as Baltostigus cf. horribilis, and may represent females of this species. However, further study based on more specimens is necessary to clarify the identity of these specimens.


Assuntos
Âmbar , Besouros , Animais , Países Bálticos , Feminino , Fósseis , Lituânia , Polônia , Federação Russa , Ucrânia
14.
Zootaxa ; 4568(3): zootaxa.4568.3.2, 2019 Mar 21.
Artigo em Inglês | MEDLINE | ID: mdl-31715843

RESUMO

Gothograptid retiolitines were distinctive in being one of the very few graptolite groups to thrive through the late Wenlock extinction event that killed off most graptoloid species, and their distinctive construction may have been a factor in this success amid environmental adversity. New and rich material from two localities in Poland and five localities in Lithuania contains Gothograptus nassa, Gothograptus obtectus and four new species. The detailed morphology and reconstruction of the tubarium shows its specific features, different from other lundgreni Biozone retiolitines. The tubarium is narrow, elongated, finite, massive and compact. The thecal orifices are hidden by simple hoods or by extraordinary reticulated veils, which may cover the ventral walls. The colonies of Gothograptus species from the lundgreni Biozone are short, usually having eight pairs of thecae, whereas species from the post-lundgreni interval may reach more than 20 pairs of thecae. A common feature of Gothograptus species is the presence of singular genicular structures tightly covering thecal orifices. Reticulated hoods and veils are characteristic of species from the lundgreni Biozone. The most common such structures are nassa hoods, located on the proximal thecae in some species from the lundgreni Biozone, and on every theca of post-lundgreni species. Only Gothograptus domeyki n. sp. has no genicular processes on most thecae. Within a total of four species from the lundgreni Biozone and three species from the nassa and praedeubeli Biozones, we describe here the new species Gothograptus domeyki and Gothograptus velo from the lundgreni Biozone, Gothograptus diminutus from the parvus/nassa Biozone, and Gothograptus auriculatus from the dubius/nassa and praedeubeli biozones; G. auriculatus n. sp. is the youngest form of the genus Gothograptus. Variation within the genus Gothograptus during the post-lundgreni interval period is shown for the first time.


Assuntos
Evolução Biológica , Gastrópodes , Animais , Lituânia , Polônia
15.
Medicina (Kaunas) ; 55(10)2019 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-31581459

RESUMO

Background and objectives: Microwave thermal ablation (MWT) is one of the treatment options for kidney cancer. However, for patients over 70 years old the safety and oncological efficacy of this treatment is still controversial. The goal of this study was to compare MWT with open partial nephrectomy (OPN) and to find out whether MWT is preferable in maintaining patient renal function and reducing the risk of postoperative complications. Materials and Methods: Depending on the treatment choice, all patients were divided into two groups: an MWT group and an open kidney resection (OPN) group. Data have been retrospectively collected for 7 years, starting with January 2012 up to January 2019. A total number of 33 patients with exophytic, single small renal masses were treated with either OPN (n = 18) or MWT (n = 15). All patients had histologically proven T1 kidney cancer. MWT was performed for patients who refused to have OPN or in those cases where the collecting system, renal calyx, and great vessels were free from tumor margins of more than 1 cm. Results: In the MWT group a median (IQR) patients' age was 75 years (71-79) years, in the OPN group-71.5 (70-75) years, p = 0.005. A median (IQR) Charleston comorbidity index in the MWT group was 7.5 (5-10) and in the same way in the OPN group it was 5.22 (5-6), p = 0.005. A median (IQR) estimated glomerular filtration rate (eGFR) before surgery was higher in the MWT group 59.9 (49.5-73.8) mL/min/1.73 m2 vs. 46.2 (42.7-65.8) mL/min/1.73 m2 in the OPN group, p = 0.12. Three days following the surgery a median (IQR) eGFR was 56.45 (46.6-71.9) in MWT group mL/min/1.73 m2 vs. 43.45 (38.3-65) mL/min/1.73 m2) in the OPN group, p = 0.30. A median (IQR) of primary hemoglobin level was lower in the MWT group compared with the OPN group (134.5 (124-140) g/L vs. 125 (108-138) g/L), p = 0.41. However, after the surgery a median (IQR) lower hemoglobin level was detected in the OPN group (123.5 (111-134) g/L vs. 126 (112-135)), p = 0.53. The median (IQR) duration of the procedure in MWT group was shorter compared with the OPN group (26 (25-30) min vs. 67.5 (55-90) min), p < 0.0001. A median (IQR) hospitalization time was shorter in MWT group (3 (2-3) days vs. 89 (7-11.5) days), p < 0.0001. Pain by the visual analogue scale (VAS) scale the first day after surgery was significantly lower-median (IQR) in the MWT group was 2 (1-3) vs. 4 (3-6)), p = 0.008. Treatment failure rate was numerically higher in MWT (1/15 vs. 0/18, p = 0.56). Conclusions: Pain level on the next day after surgery, mean number of hospitalization and operation time were significantly lower in the MWT group than in the OPN group. The blood loss estimated glomerular filtration rate and oncologic data between the two groups was not statistically significant.


Assuntos
Carcinoma de Células Renais/cirurgia , Neoplasias Renais/cirurgia , Idoso , Carcinoma de Células Renais/mortalidade , Ablação por Cateter , Feminino , Taxa de Filtração Glomerular , Humanos , Neoplasias Renais/mortalidade , Lituânia , Masculino , Micro-Ondas , Nefrectomia , Duração da Cirurgia , Estudos Retrospectivos , Análise de Sobrevida , Resultado do Tratamento
16.
Artigo em Inglês | MEDLINE | ID: mdl-31618913

RESUMO

Emerging data indicates that melanoma may be linked to prostate cancer. We evaluated if the incidence of melanoma was associated with subsequent risk of prostate cancer (PC). We extracted data from the Lithuanian cancer registry from 1993 to 2012. We calculated the standardized incidence ratios (SIRs) for PC as a ratio of observed number of cancer cases in people with previous melanoma diagnosis to the expected number of cancer cases in the underlying general population. Therein, 95% confidence intervals for the SIRs were estimated assuming the number of observed cancer cases follows the Poisson distribution. Overall, 65 PCs were observed versus 52.5 expected (SIR 1.24; 95% CI: 0.97-1.58) within a period of 24 years. A significantly increased risk of PC was found in patients with melanoma diagnosis over 70 years (SIR 1.62; 95% CI: 1.11-2.39) and in two periods of diagnosis (SIRs 1.76 and 1.62 in 1993-1997 and 2009-2012, respectively). A significantly increased risk was also found five to nine years after melanoma diagnosis (SIR 1.58; 95% CI: 1.05-2.38). Further studies are needed to evaluate the relationship between melanoma and subsequent risk of prostate cancer.


Assuntos
Melanoma/epidemiologia , Neoplasias da Próstata/epidemiologia , Neoplasias Cutâneas/epidemiologia , Idoso , Humanos , Incidência , Lituânia/epidemiologia , Masculino , Pessoa de Meia-Idade , Sistema de Registros
17.
Medicina (Kaunas) ; 55(9)2019 Aug 30.
Artigo em Inglês | MEDLINE | ID: mdl-31480363

RESUMO

Background and objectives: The aim of this study was to analyze trends in testicular cancer incidence, mortality, and survival in Lithuania during the period 1998-2013. Materials and Methods: The study was based on all cases of testicular cancer reported to the Lithuanian Cancer Registry between 1998 and 2013. Age group-specific rates and standardized rates were calculated using the direct method (European standard population). The Joinpoint regression model was used to provide the annual percentage change (APC). Five-year relative survival estimates were calculated using period analysis. Relative survival was calculated as the ratio of the observed survival of cancer patients and the expected survival of the underlying general population. Results: During the study period, the age-standardized incidence rate of testicular cancer increased from 1.97 to 3.45 per 100,000, with APC of 2.97% (95% CI 0.9 to 5.1). Incidence rate of seminomas changed from 0.71 to 1.54 per 100,000, with APC of 2.61% (95% CI -0.4 to 5.7), and the incidence rate of non-seminomas increased from 0.84 to 1.83 per 100,000, with APC of 4.16% (95% CI 1.6 to 6.8). The mortality rate of testicular cancer in Lithuania during this period declined from 0.78 to 0.51 per 100,000, with APC of -2.91% (95% CI -5.5 to -0.3). Relative five-year survival ratio for the period 2009-2013 was 89.39% (95% CI 82.2 to 94.4). In our study, the overall five-year relative survival increased slightly (10.1%) from 2004-2008 to 2009-2013 (from 79.3% to 89.4%). Conclusions: A moderate increase of testicular cancer incidence has been observed in Lithuania between the years 1998 and 2013, while the mortality rate decreased. The five-year relative survival increased according to different period estimates; however, the results could have been higher if a multidisciplinary approach to diagnostics and management in the concerned centers had been implemented in Lithuania as in other countries.


Assuntos
Neoplasias Embrionárias de Células Germinativas/epidemiologia , Seminoma/epidemiologia , Neoplasias Testiculares/epidemiologia , Adolescente , Adulto , Criança , Humanos , Incidência , Lituânia/epidemiologia , Masculino , Pessoa de Meia-Idade , Neoplasias Embrionárias de Células Germinativas/mortalidade , Seminoma/mortalidade , Taxa de Sobrevida , Neoplasias Testiculares/mortalidade
18.
Mar Pollut Bull ; 149: 110546, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31543486

RESUMO

Vibrio spp. are bacteria that inhabit fresh and marine waters throughout the world and can cause severe infections in humans. This study aimed to investigate the presence of potentially pathogenic Vibrio bacteria in the coastal waters of the Lithuanian Baltic Sea and the Curonian Lagoon. The results of cultivation on TCBS media showed that total abundance of Vibrio spp. varied from 1.2 × 102 to 6 × 104 CFU L-1. Real-time PCR revealed that the V. vulnificus vvhA gene varied from 2.8 × 103 to 3.7 × 104 copies L-1, with the highest amounts in sites with average water salinity of 7.1 PSU. Both green and blue-green algae and lower salinity play a role in the growth and spread of total Vibrio spp. Although potential infection risk was low at the time of this study, regular monitoring of Vibrio spp. and infection risk assessments are recommended.


Assuntos
Água do Mar/microbiologia , Vibrio cholerae/isolamento & purificação , Vibrio vulnificus/isolamento & purificação , Praias , Cianobactérias , Monitoramento Ambiental , Humanos , Lituânia , Fitoplâncton , Reação em Cadeia da Polimerase em Tempo Real , Medição de Risco , Salinidade , Temperatura , Vibrioses/microbiologia , Vibrio cholerae/genética , Vibrio vulnificus/genética , Microbiologia da Água
19.
Artigo em Inglês | MEDLINE | ID: mdl-31540214

RESUMO

Health literacy as a set of competencies to promote and sustain health has received significant research attention, particularly in studies on adults. Improving health literacy at an early age is crucial to personal health and development, so there is a need to investigate the health literacy of school-aged children. The aims of this study were to determine the level of subjective health literacy among adolescents in Lithuania and to examine the association between health literacy, school achievement, health education in schools, and family affluence. Health literacy was assessed using a brief Health Literacy for School-Aged Children instrument on a representative sample of 2369 subjects (from the 7th to 10th grades). Overall, 12.1% of all respondents had low, 70.5% moderate, and 17.4% a high level of health literacy. School achievements were found to be a significant predictor of health literacy, as were the number of school-based health promotion events. Family affluence also predicted an increased level of health literacy. This study was the first nationally representative examination of this topic in Lithuania and it highlighted the alarming finding that less than one-fifth of adolescents had high health literacy.


Assuntos
Letramento em Saúde , Sucesso Acadêmico , Adolescente , Feminino , Humanos , Lituânia , Masculino , Serviços de Saúde Escolar , Instituições Acadêmicas , Autorrelato
20.
BMC Public Health ; 19(1): 1242, 2019 Sep 09.
Artigo em Inglês | MEDLINE | ID: mdl-31500616

RESUMO

BACKGROUND: Migraine is a primary headache disorder which affects all aspects of life. The financial burden of migraine imposed on the society might be substantial. This study aims at estimating the economic cost of migraine in Latvia and Lithuania, including both direct and indirect costs. Direct costs encompass the costs of migraine-related health care resource utilization. Indirect costs are related to productivity loss, the potential or expected earnings lost due to migraine. METHODS: Direct cost is assessed by using the prevalence method, a widely used cost-of-illness approach. The prevalence rate of migraine and the migraine-related health care resource utilization are proxied from the literature, whereas unit cost of medical services and procedures are retrieved from national databases and providers. For estimating the indirect cost of migraine, we follow the human capital approach. We quantify three components of indirect costs: reduced labour force participation, absence from work and reduced productivity while at work. The number of unemployed migraineurs, days missed from work and days lost due to impairment while at work are drawn from the literature. Unemployment rate and average income in Latvia and Lithuania are then inserted to assess indirect costs. RESULTS: We find that the mean per-person total cost of migraine is €801 annually in Latvia, and €721 in Lithuania. In both countries around 30% of total cost is direct cost; cost related to a wide array of migraine-related medical services and interventions. The total cost of migraine is €112.26 million in Latvia, corresponding to 0.42% of Latvia's GDP. The total cost of migraine is €149.62 million in Lithuania, corresponding to 0.35% of Lithuania's GDP. In both countries two thirds of total cost is related to lost workdays due to absenteeism and presenteeism. CONCLUSIONS: The financial burden of migraine imposed on the society is substantial in Latvia and Lithuania. Improvements in care for patients with migraine, such as easier access to structured headache assessment services, wider availability of various procedures and preventive medications would significantly increase direct costs. Nevertheless, this cost increase might be far outweighed by lower migraine-related productivity loss, especially as the prevalence of migraine is the highest in the most productive years of life.


Assuntos
Efeitos Psicossociais da Doença , Transtornos de Enxaqueca/economia , Adulto , Eficiência , Feminino , Custos de Cuidados de Saúde/estatística & dados numéricos , Humanos , Letônia/epidemiologia , Lituânia/epidemiologia , Masculino , Pessoa de Meia-Idade , Transtornos de Enxaqueca/epidemiologia , Prevalência
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