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1.
J Appl Oral Sci ; 28: e20190005, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31800870

RESUMO

other: Chitosan is a natural, biocompatible chelating substance with potential for dental use. This study compared the effects of final canal irrigation with chitosan and EDTA on dentin microhardness, sealer dentin tubules penetration capacity, and push-out strength. METHODOLOGY: Fifty canine roots were distributed according to the final irrigation protocol (n=10): G1- 15% EDTA with conventional irrigation; G2- 15% EDTA with Endovac; G3- 0.2% chitosan with conventional irrigation; G4- 0.2% chitosan with Endovac; and G5- without irrigation. Specimens were obturated (AH Plus) and sectioned in 3 slices per root third. The first slice was used for microhardness and sealer penetration assessments under a laser confocal microscope. The second was utilized in a push-out strength test. The third slice was discarded. Data were analyzed using 2-way ANOVA and Tukey's post hoc test (α<0.05). Failure mode was determined at x40 magnification. RESULTS: Microhardness reduction was more significant in groups G2 and G4 (p<0.05). Sealer penetration through dentin was significantly greater in group G2 (p<0.05). There was no significant difference between groups G1, G3, and G4 (p>0.05). In general, all experimental groups presented similar bond resistance (p>0.05) that significantly differed from the control (p<0.001). Mixed type failures were predominant. CONCLUSIONS: In general, 0.2% chitosan and 15% EDTA solutions act in a similar manner with regard to the variables studied. The use of Endovac potentiates the effect of these solutions.


Assuntos
Quelantes/química , Quitosana/química , Colagem Dentária/métodos , Dentina/efeitos dos fármacos , Ácido Edético/química , Irrigantes do Canal Radicular/química , Análise de Variância , Resinas Epóxi/química , Testes de Dureza , Humanos , Teste de Materiais , Microscopia Confocal , Pessoa de Meia-Idade , Valores de Referência , Reprodutibilidade dos Testes , Materiais Restauradores do Canal Radicular/química , Resistência ao Cisalhamento , Propriedades de Superfície/efeitos dos fármacos
2.
Rev. Soc. Odontol. La Plata ; 29(57): 15-19, dic. 2019. ilus, tab
Artigo em Espanhol | LILACS | ID: biblio-1050826

RESUMO

Se determinó la solubilidad en agua en ensayos in-vitro de un sellador para uso endodóntico a base de un conglomerado de trióxidos minerales (MTA), marca Endosealer® (Densell SA) de acuerdo a la norma UNE-EN ISO 6876:2012. En el ensayo de solubilidad en agua durante 24 hs se encontró pérdida de masa (3,3 %) y la presencia de sólidos en las aguas de lavado (6,4 %). Esto indica que durante el ensayo ocurre la solubilización de parte del material y la incorporación de agua, lo que no permite establecer un valor real de la solubilidad (AU)


Solubility of a commercial endodontic sealer (Endosealer® (Densell SA)) was performed according to the UNE-EN ISO 6876:2012. The results show a mass loss of 3.3 % and 6.4 % of solid in the test solution. These indicate that during the solubility test part of the material solubilizes and an actual value of solubility cannot feasible be determined (AU)


Assuntos
Materiais Restauradores do Canal Radicular/química , Solubilidade , Materiais Biocompatíveis , Técnicas In Vitro , Análise Estatística
3.
Int J Nanomedicine ; 14: 8379-8398, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31695372

RESUMO

Background: Propolis is a unique natural adhesive product collected by honeybees. It contains a diversity of bioactive compounds with reported functional properties such as antioxidants, antibacterial, antifungal, anti-inflammatory, antiviral and anticancer activity. Dental caries is a worldwide problem that caused by microbial growth usually progress from tooth enamel to the underlying pulpal tissues and root canal. This situation could be controlled by a sequence of steps to remove microorganisms and fill root canal with a suitable long-lasting root canal sealer. Unfortunately, leachable and degradation products of the currently used sealers compromised their antimicrobial activity by inflammatory modulation associated with irritation and toxicity of periapical tissues. Materials and methods: Hence, propolis was selected to be designed as a natural root canal sealer due to its amazing functional properties. Moreover, its handling properties were enhanced and potentiated by its incorporation in polymeric nanoparticles (NPs). Frist, propolis was collected, extracted and analyzed for its bioactive compounds. After that, propolis-loaded NPs of PLGA (ProE-loaded NPs) were developed and fully characterized regarding physicochemical properties, in vitro release and in vitro cytotoxicity. Then, root canal sealers were fabricated and assayed for their antimicrobial activity. Both cytotoxicity and antimicrobial activity were compared to those of a model sealer; AH Plus®. Results: The results revealed that spherical nanoscopic NPs with narrow size distribution were obtained. ProE-loaded NPs exhibited accepted entrapment efficiency (>80) and prolonged release. In vitro cytotoxicity study confirmed the safety of ProE-loaded NPs. Also, the developed sealers showed antimicrobial activity versus bacterial strains of Enterococcus faecalis and Streptococcus mutans and antifungal activity against Candida albicans. Conclusion: ProE-loaded NPs could be incorporated in and represented as a root canal sealer with prolonged release and enhanced cytocompatibility as well as antimicrobial activities.


Assuntos
Antibacterianos/farmacologia , Nanopartículas/química , Própole/farmacologia , Materiais Restauradores do Canal Radicular/farmacologia , Cimento de Óxido de Zinco e Eugenol/farmacologia , Varredura Diferencial de Calorimetria , Candida albicans/efeitos dos fármacos , Linhagem Celular , Sobrevivência Celular/efeitos dos fármacos , Liberação Controlada de Fármacos , Egito , Enterococcus faecalis/efeitos dos fármacos , Humanos , Cinética , Teste de Materiais , Testes de Sensibilidade Microbiana , Nanopartículas/ultraestrutura , Materiais Restauradores do Canal Radicular/química , Streptococcus mutans/efeitos dos fármacos
4.
Braz Oral Res ; 33: e042, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31508725

RESUMO

This study evaluated the cytotoxicity and biocompatibility of a new bioceramic endodontic sealer (i.e., Sealer Plus BC) in comparison with those of MTA Fillapex and AH Plus. L929 fibroblasts were cultured and Alamar Blue was used to evaluate cell viability of diluted extracts (1:50, 1:100, and 1:200) from each sealer at 24 h. Polyethylene tubes that were filled with material or empty (as a control) were implanted in the subcutaneous tissue of rats. The rats were killed after 7 and 30 d (n = 8), and the tubes were removed for histological analysis. Parametric data was analyzed using a one-way ANOVA test, and nonparametric data was analyzed via the Kruskal-Wallis test followed by the Dunn test (p < 0.05). A reduction in cell viability was observed in the extracts that were more diluted for Sealer Plus BC when compared to that of Control and AH Plus (p < 0.05). However, the 1:50 dilution of the Sealer Plus BC was similar to that of the Control (p > 0.05). Conversely, more diluted extracts of MTA Fillapex (1:200) and AH Plus (1:100 and 1:200) were similar to the Control (p > 0.05). Histological analysis performed at 7 d did not indicate any significant difference between tissue response for all materials, and the fibrous capsule was thick (p > 0.05). At 30 d, Sealer Plus BC was similar to the Control (p > 0.05) and MTA Fillapex and AH Plus exhibited greater inflammation than the Control (p < 0.05). The fibrous capsule was thin for the Control and for most specimens of Sealer Plus BC and AH Plus. Thus, Sealer Plus BC is biocompatible when compared to MTA Fillapex and AH Plus, and it is less cytotoxic when less-diluted extracts are used.


Assuntos
Cimentos para Ossos/química , Hidróxido de Cálcio/química , Cerâmica/química , Materiais Restauradores do Canal Radicular/química , Compostos de Alumínio/química , Animais , Materiais Biocompatíveis , Cimentos para Ossos/farmacologia , Cimentos para Ossos/toxicidade , Compostos de Cálcio/química , Hidróxido de Cálcio/farmacologia , Hidróxido de Cálcio/toxicidade , Sobrevivência Celular/efeitos dos fármacos , Células Cultivadas/efeitos dos fármacos , Combinação de Medicamentos , Resinas Epóxi/química , Fibroblastos/efeitos dos fármacos , Técnicas In Vitro , Inflamação , Masculino , Teste de Materiais , Óxidos/química , Ratos Wistar , Materiais Restauradores do Canal Radicular/toxicidade , Silicatos/química , Tela Subcutânea/patologia
5.
J Appl Oral Sci ; 27: e20180556, 2019 Sep 09.
Artigo em Inglês | MEDLINE | ID: mdl-31508791

RESUMO

OBJECTIVE: To evaluate the effect of ultrasonic and sonic activation on physicochemical properties of AH Plus, MTA Fillapex, ADSeal, GuttaFlow Bioseal, and GuttaFlow 2 sealers. METHODOLOGY: Three experimental groups were formed: no activation (NA), ultrasonic activation (UA), and sonic activation (SA). The sealers were manipulated according to the manufacturers' instructions. A 3-mL syringe was adapted to receive 1 mL of sealer. Activation was performed with a 20/.01 ultrasonic insert (20 s/1W) in the UA group. A size 35.04 sonic tip was used (20 s/10,000 cycles/min-1) in the SA group. The molds for physicochemical analysis were filled and evaluated according to ANSI/ADA specification no. 57: setting time (ST), flow (FL), dimensional change (DC), solubility (SB), and radiopacity (RD). Statistical analysis was performed by Kruskal-Wallis, one-way ANOVA, and Tukey's tests (P<0.05). RESULTS: Regarding ST, only AH Plus and GuttaFlow 2 in the NA group met the ANSI/ADA standards. All FL values were greater than 20 mm in diameter, as determined by ANSI/ADA. The tested sealers and protocols did not comply with the ANSI/ADA standards for DC. As for SB, only MTA Fillapex, regardless of the activation protocol, did not follow the ANSI/ADA standards. All of the investigated sealers, regardless of the activation protocol, presented radiographic density higher than 3 mm Al, as proposed by ANSI/ADA. CONCLUSIONS: UA and SA promoted changes in the physicochemical properties of the evaluated root canal sealers, mainly in ST and F. Thus, it is important to evaluate the physicochemical properties of endodontic sealers associated with activation techniques prior to clinical application in order to determine whether the properties follow the parameters set by ANSI/ADA, ensuring safety and quality of root canal filling.


Assuntos
Compostos de Alumínio/química , Compostos de Cálcio/química , Dimetilpolisiloxanos/química , Resinas Epóxi/química , Guta-Percha/química , Óxidos/química , Materiais Restauradores do Canal Radicular/química , Silicatos/química , Ondas Ultrassônicas , Análise de Variância , Combinação de Medicamentos , Teste de Materiais , Valores de Referência , Reprodutibilidade dos Testes , Solubilidade , Estatísticas não Paramétricas , Propriedades de Superfície , Fatores de Tempo
6.
Niger J Clin Pract ; 22(8): 1091-1098, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31417052

RESUMO

Aims: Our aim was to compare three different voxel sizes of CBCT images for the determination of residual filling material volume in root canals when compared with micro CT. Material and Methods: Forty-two root canals of 14 extracted human maxillary molar teeth were retreated by using ProFile® instruments. Images were obtained after retreatment by using ProMax 3D Max CBCT at 3 different voxel sizes (1) High resolution (0.1 mm); (2) High definition (0.15 mm); and (3) Normal resolution (0.2 mm). Two observers measured volumes of residual filling materials in exported CBCT images by means of 3D Doctor Software. Micro CT measurements were served as gold standard. Mann-Whitney U test and Wilcoxon Test were used for the comparison of CBCT and micro CT measurements. Statistical significance was set at P < 0.05. Results: No statistically differences were found between the two observers for all measurements (P > 0.05). There were no significant differences among different CBCT voxel sizes used (0.1 mm, 0.15 mm, and 0.2 mm) (P > 0.05). The Spearman correlation coefficients between CBCT at different voxel sizes significantly highly correlated with micro CT measurements for each observer (P < 0.05). Furthermore, no significant differences were found between the measurements obtained by the two observers in consideration to root canal location (P > 0.05). Conclusion: CBCT images may provide useful information in the volumetric assessment of the amount of residual filling material in root canals for retreatment procedures.


Assuntos
Cavidade Pulpar/diagnóstico por imagem , Dente Molar/diagnóstico por imagem , Dente Molar/cirurgia , Retratamento , Materiais Restauradores do Canal Radicular/química , Obturação do Canal Radicular/métodos , Tratamento do Canal Radicular/métodos , Tomografia Computadorizada de Feixe Cônico Espiral/métodos , Materiais Dentários , Humanos , Processamento de Imagem Assistida por Computador/métodos , Materiais Restauradores do Canal Radicular/uso terapêutico , Preparo de Canal Radicular/métodos , Microtomografia por Raio-X/métodos
7.
BMC Oral Health ; 19(1): 181, 2019 08 08.
Artigo em Inglês | MEDLINE | ID: mdl-31395103

RESUMO

BACKGROUND: The purpose of this experiment was to assess the push out bond strength of Polydimethylsiloxane sealers (GuttaFlow 2 and GuttaFlow Bioseal by Colte'ne/Whaledent, Altstätten, Switzerland). AH Plus (Dentsply, DeTrey, Konstanz, Germany) was used as a reference material for comparison. METHODS: Thirty root slices were prepared from the middle third of 10 mandibular premolars. Each slice was 1 ± 0.1 mm thick. Three holes, 0.8 mm wide each, were drilled on the axial side of each root slice. These holes were subjected to standardized irrigations and then dried using paper points. Finally, for each root slice, each hole was filled with exactly one of the following three root canal sealers: AH Plus, GuttaFlow 2 and GuttaFlow Bioseal. After all the holes were filled in that way, the root slices were stored on top of phosphate-buffered saline solution (pH 7.2) soaked gauze for 7 days at the temperature of 37 degrees Celsius. Then, for each root canal sealer on a root slice, the universal testing machine was used to measure the push out bond strength. The differences in push out bond strengths between the three sealer samples were assessed using the Friedman test, while the paired comparisons were assessed using Wilcoxon signed rank test with Bonferroni correction. All statistical tests were two-tailed and the significance level was set at the 5%. RESULTS: According to the Friedman test the distributions of push out bond strengths of AH Plus, GuttaFlow 2 and GuttaFlow Bioseal were different (P < 0.05). Paired comparisons indicated that AH Plus had a significantly superior push out bond strength than GuttaFlow 2 and GuttaFlow Bioseal, while the push out bond strength of GuttaFlow Bioseal was significantly stronger than that of GuttaFlow 2 (P < 0.01). CONCLUSIONS: Based on these findings, AH Plus is a better root canal sealer than GuttaFlow 2 and GuttaFlow Bioseal.


Assuntos
Colagem Dentária/métodos , Dimetilpolisiloxanos/química , Materiais Restauradores do Canal Radicular/química , Silicatos/uso terapêutico , Dentina/química , Combinação de Medicamentos , Resinas Epóxi , Guta-Percha , Humanos , Teste de Materiais , Materiais Restauradores do Canal Radicular/uso terapêutico , Irrigantes do Canal Radicular/química , Cimento de Óxido de Zinco e Eugenol
8.
J Endod ; 45(10): 1248-1252, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31447172

RESUMO

INTRODUCTION: Calcium silicate-based materials have been proposed as root canal sealers for root canal treatment. The aim of this study was to evaluate the physicochemical properties of a new calcium silicate-based sealer (Bio-C Sealer; Angelus, PR, Brazil) compared with a calcium silicate endodontic sealer (TotalFill BC Sealer; FKG Dentaire SA, La Chaux-de-Fonds, Switzerland) and an epoxy resin sealer (AH Plus; Dentsply DeTrey, Konstanz, Germany). METHODS: The setting time and flow were evaluated based on ISO 6876 standard. The pH value was evaluated after different time intervals of storage in deionized water (1, 7, 14, and 21 days). Radiopacity was evaluated by radiographic analysis in millimeters of aluminum. Solubility and volumetric change were evaluated after 30 days of immersion in distilled water. Solubility was assessed by mass loss (%), and volumetric change was evaluated by micro-computed tomographic imaging. The data were submitted to analysis of variance and Tukey statistical tests (P < .05). RESULTS: TotalFill BC Sealer and Bio-C Sealer were similar regarding radiopacity, volumetric change, and pH values (P > .05). Bio-C Sealer presented the shortest setting time and the highest flow and solubility (P < .05). AH Plus showed the highest radiopacity and the lowest flow, pH, solubility, and volumetric change (P < .05). CONCLUSIONS: Bio-C Sealer showed a short setting time, alkalinization ability, and adequate flow and radiopacity as well as low volumetric change. However, this sealer had higher solubility than the rates required by ISO 6876 standard.


Assuntos
Compostos de Cálcio , Materiais Restauradores do Canal Radicular , Silicatos , Compostos de Cálcio/química , Combinação de Medicamentos , Resinas Epóxi , Teste de Materiais , Materiais Restauradores do Canal Radicular/química , Silicatos/química
9.
J Appl Biomater Funct Mater ; 17(3): 2280800019851771, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31373255

RESUMO

BACKGROUND: The main microorganism associated with the failure of endodontic treatments is Enterococcus faecalis. Although several endodontic therapeutics have demonstrated antimicrobial activity against E. faecalis, the antimicrobial effectiveness of chitosan (CsNPs) and silver nanoparticles (AgNPs) included into conventional endodontic sealers for endodontic therapies is still unclear. AIM: The objective of this study was to evaluate the antibacterial activity increment (AAI) of endodontic sealers containing CsNPs and AgNPs as well as some chemical components against E. faecalis by direct contact assays. METHODS: CsNPs and AgNPs were synthesized by reduction and ionic gelation methods, respectively. Nanoparticles were characterized by dynamic light scattering and energy dispersive X-ray analysis. The bactericidal activity was tested on monolayers on agar plates and collagen membrane surface assays against E. faecalis. RESULTS: The size of CsNPs was 70.6±14.8 nm and zeta potential was 52.0±5.4 mV; the size of AgNPs was 54.2±8.5 nm, and zeta potential was -48.4±6.9 mV. All materials, single or combined, showed an AAI, especially when CsNPs, chlorhexidine (Chx), and the combination of CsNPs-Chx were added. However, the combination of CsNPs-Chx showed the highest (55%) AAI, followed by Chx (35.5%) and CsNPs (11.1%), respectively. There was a significant statistical difference in all comparisons (p < 0.05). Tubliseal (40%) and AH Plus (32%) sealants showed a higher AAI on E. faecalis in the monolayer test and collagen membrane assay analyzed by scanning electron microscopy. CONCLUSIONS: Tubliseal and AH plus sealers combined with nanoparticles, especially CsNPs-Chx, could be used for conventional endodontic treatments in the control of E. faecalis bacteria.


Assuntos
Antibacterianos , Quitosana , Enterococcus faecalis/crescimento & desenvolvimento , Nanopartículas Metálicas/química , Materiais Restauradores do Canal Radicular , Prata , Antibacterianos/química , Antibacterianos/farmacologia , Quitosana/química , Quitosana/farmacologia , Enterococcus faecalis/ultraestrutura , Humanos , Nanopartículas Metálicas/ultraestrutura , Microscopia Eletrônica de Varredura , Materiais Restauradores do Canal Radicular/química , Materiais Restauradores do Canal Radicular/farmacologia , Prata/química , Prata/farmacologia
10.
Gen Dent ; 67(5): 54-57, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31454324

RESUMO

This study was designed to evaluate the effect of a final rinse with 0.2% chitosan solution on the adhesion in roots filled with gutta percha and an epoxy resin based sealer. Thirty extracted human maxillary canines selected to ensure specimen standardization were used in the study. After the coronal portion of each tooth was removed, the roots were instrumented and irrigated with 1% sodium hypochlorite (NaOCl). Roots were distributed into 3 groups according to the final rinsing solution (n = 10): 0.2% chitosan, 17% ethylenediaminetetraacetic acid (EDTA), or 1% NaOCl. The canals were irrigated with 5 mL of each solution for 5 minutes and then filled with gutta percha cones and the resin based sealer. Ten roots in each group were prepared, sectioned, and submitted to push-out testing. Data were analyzed with analysis of variance and Tukey test (P < 0.05). In the push-out test, final irrigation with chitosan (mean, 0.37 [SD, 0.12] MPa) or EDTA (0.38 [0.11] MPa) resulted in significantly greater bond strength of the sealer to the root canal (P < 0.05) than did irrigation with 1% NaOCl (0.13 [0.04] MPa). The cervical third had greater bond strength than the other thirds (P < 0.05). Adhesive failure was the most frequent type in all groups. A final rinse with 0.2% chitosan or 17% EDTA resulted in greater bond strength of root fillings to the root canal than did 1% NaOCl.


Assuntos
Quitosana , Colagem Dentária , Materiais Restauradores do Canal Radicular , Quitosana/química , Cavidade Pulpar , Dentina , Resinas Epóxi , Humanos , Materiais Restauradores do Canal Radicular/química , Irrigantes do Canal Radicular , Preparo de Canal Radicular , Hipoclorito de Sódio
11.
Braz Oral Res ; 33: e057, 2019 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-31365704

RESUMO

The aim of this study was to evaluate the effect of peracetic acid (PAA) as a single irrigant on the smear layer, on the intraradicular dentinal bond strength, and on the penetrability of an epoxy-based resin sealer into the dentinal tubules. A total of 120 roots were distributed into 4 groups according to the irrigant used in root canal preparation: 1% PAA (PAA); 2.5% NaOCl followed by final irrigation with 17% EDTA and 2.5% NaOCl (NaOCl-EDTA-NaOCl); 2.5% NaOCl (NaOCl); and saline solution (SS). The smear layer was evaluated using scanning electron microscopy. The bond strength of an epoxy-based resin sealer (AH Plus) to root dentin was evaluated by the push-out test and penetrability of the sealer into dentinal tubules was observed by confocal laser microscopy. The results were analyzed by the Kruskal-Wallis and the Dunn post-test (α = 0.05). The use of 1% PAA as single root canal irrigant provided smear layer removal and improved the penetrability and bond strength of AH Plus to root dentin in a manner similar to that of the NaOCl-EDTA-NaOCl group (p > 0.05). The NaOCl and SS groups had higher values of smear layer and lower values of sealer penetrability and dentin bond strength than the PAA and NaOCl-EDTA-NaOCl groups (p < 0.05). Thus, 1% PAA has the potential to be used as a single irrigant in root canals.


Assuntos
Cavidade Pulpar/efeitos dos fármacos , Dentina/efeitos dos fármacos , Resinas Epóxi/química , Ácido Peracético/química , Materiais Restauradores do Canal Radicular/química , Irrigantes do Canal Radicular/química , Camada de Esfregaço/química , Colagem Dentária/métodos , Cavidade Pulpar/química , Dentina/química , Ácido Edético/química , Humanos , Teste de Materiais , Microscopia Confocal , Microscopia Eletrônica de Varredura , Valores de Referência , Reprodutibilidade dos Testes , Hipoclorito de Sódio/química
12.
Niger J Clin Pract ; 22(7): 926-931, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31293256

RESUMO

Background: This study was performed to evaluate the amount of apically extruded debris removed from a root canal filled with cold lateral condensation (CLC), and warm vertical compaction (WVC) techniques, using b or a phase gutta-percha with AH-Plus (Dentsply DeTrey, Konstanz, Germany) or Resilon (Resilon Research LLC, Madison, WI) with RealSeal SE (SybronEndo, Amersfoort, The Netherlands). Materials and Methods: About 100 human incisor teeth were prepared with a #25.06 NiTi rotary system and divided into five groups according to the filling material used: Group 1: CLC (gutta-percha, AH-Plus); Group 2: WVC (b phase gutta-percha, AH-Plus); Group 3: WVC (a phase gutta-percha, AH-Plus); Group 4: CLC (Resilon, RealSeal SE); and Group 5: WVC (Resilon, RealSeal SE). Extruded debris during the retreatment procedure was collected in preweighed Eppendorf tubes. The times required for retreatment were recorded. Results: The amount of debris extrusion was significantly greater with WVC than CLC in the gutta-percha and Resilon groups (P < 0.001). Using a phase gutta-percha resulted in significantly more debris extrusion than b phase gutta-percha (P < 0.001). In the WVC groups, Resilon caused significantly more debris extrusion than gutta-percha (P < 0.05). Retreatment was faster for CLC than WVC (P < 0.05). Conclusions: In the retreatment procedure, the amount of apically extruded debris and retreatment duration were dependent on the type of obturation material and technique used.


Assuntos
Cavidade Pulpar/cirurgia , Guta-Percha/química , Materiais Restauradores do Canal Radicular/química , Preparo de Canal Radicular/instrumentação , Preparo de Canal Radicular/métodos , Tratamento do Canal Radicular/instrumentação , Ligas Dentárias/química , Humanos , Níquel , Retratamento , Materiais Restauradores do Canal Radicular/efeitos adversos , Obturação do Canal Radicular/métodos , Titânio/química , Ápice Dentário/patologia
13.
Biomed Res Int ; 2019: 4676354, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31211137

RESUMO

The incorporation of nanoparticles into endodontic sealers aims at increasing antimicrobial activity of the original material. Aim. The aim of this study is to incorporate the nanostructured silver vanadate decorated with silver nanoparticles (AgVO3, at 2.5%, 5%, and 10%) into three endodontic sealers and evaluate the antibacterial activity of freshly sealers, surface topography and chemical composition, and setting time. Material and Methods. The AgVO3 was incorporated into AH Plus, Sealer 26, and Endomethasone N at concentrations 0%, 2.5%, 5%, and 10% (in mass). The antibacterial activity of freshly sealers was assessed by direct contact with Enterococcus faecalis and CFU/mL count (n=10), surface topography, and chemical composition were measured by SEM/EDS, and the setting time was measured by Gillmore needle (n=10). The Kruskal-Wallis and Dunn statistical tests were applied (α=0.05). Results. All groups of sealers evaluated inhibited E. faecalis (p>0.05). The incorporation of AgVO3 altered the atomic proportions between components of the endodontic sealers, and the percentage of silver (Ag) and vanadium (V) increased proportionally to the concentrations of AgVO3. Topography analysis showed differences in components distribution on the surface of the specimens. The sealers incorporated with AgVO3 of AH Plus presented a lower setting time than the control group (p<0.05). For Sealer 26 and Endomethasone N, the incorporation of AgVO3 increased the setting time in relation to control group (p<0.05). Conclusions. The modification of endodontic sealers by AgVO3 increased the atomic percentage of Ag and V proportionally to the concentration of the nanomaterial and changed the atomic percentage of the sealer components and setting times. It cannot be affirmed that the AgVO3 promote differences in the antimicrobial activity of freshly sealers, and further investigations of the antimicrobial activity of the set sealers should be carried out.


Assuntos
Antibacterianos , Bismuto , Hidróxido de Cálcio , Enterococcus faecalis/crescimento & desenvolvimento , Nanoestruturas/química , Materiais Restauradores do Canal Radicular , Compostos de Prata , Vanadatos , Antibacterianos/farmacologia , Bismuto/química , Bismuto/farmacologia , Hidróxido de Cálcio/química , Hidróxido de Cálcio/farmacologia , Dexametasona/química , Dexametasona/farmacologia , Combinação de Medicamentos , Formaldeído/química , Formaldeído/farmacologia , Humanos , Hidrocortisona/química , Hidrocortisona/farmacologia , Materiais Restauradores do Canal Radicular/química , Materiais Restauradores do Canal Radicular/farmacologia , Compostos de Prata/química , Compostos de Prata/farmacologia , Timol/análogos & derivados , Timol/química , Timol/farmacologia , Vanadatos/química , Vanadatos/farmacologia
14.
Braz Oral Res ; 33: e049, 2019 May 27.
Artigo em Inglês | MEDLINE | ID: mdl-31141039

RESUMO

The aim of the present study was to assess the penetration capacity of two endodontic cements, Endosequence BC Sealer and AH Plus, in artificial lateral canals. Twenty-six two-rooted, maxillary first premolars were instrumented to size 40.06 using K3 files. In each root, six lateral canals of two diameters (0.06 and 0.10 mm) were created with a working length of 2, 4, and 6 mm. The specimens were randomly divided into two groups according to the endodontic cement to be used (Endosequence BC Sealer and AH Plus) and obturated by the single-cone technique. The specimens were imaged by digital periapical radiography and scores from 0 to 4 were attributed according to the degree of penetration by sealers into the lateral canals. Data were analyzed statistically by Kruskal-Wallis and Student-Newman-Keuls tests, and a significance level of p < 0.05 was adopted. No significant difference was observed between the two endodontic cements used to fill the simulated lateral canals (p > 0.05). The diameter of lateral canals only influenced the capacity of the Endosequence BC Sealer in filling the canals, and presented greater penetration in the lateral canals of diameter 0.10 mm (p < 0.05). We concluded that the bioceramic endodontic cement Endosequence BC Sealer presented similar ability as AH Plus to fill simulated lateral canals.


Assuntos
Fosfatos de Cálcio/química , Cerâmica/química , Cavidade Pulpar/efeitos dos fármacos , Resinas Epóxi/química , Óxidos/química , Materiais Restauradores do Canal Radicular/química , Silicatos/química , Combinação de Medicamentos , Humanos , Teste de Materiais , Distribuição Aleatória , Valores de Referência , Reprodutibilidade dos Testes , Obturação do Canal Radicular/métodos , Estatísticas não Paramétricas
15.
Clin Oral Investig ; 23(12): 4417-4423, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31025194

RESUMO

OBJECTIVES: The aim of this study was to evaluate the mineral deposition, push-out bond strength, radiopacity, the degree of conversion, film thickness, flow, calcium ion release, and pH of experimental endodontic sealers containing hydroxyapatite (HAp), aflfa-ticalcium phosphate (α-TCP), or octacalcium phosphate (OCP) particles. MATERIALS AND METHODS: Fifty single straight root human premolars were instrumented and divided into five groups (n = 10). Experimental endodontic sealers were formulated by 70 wt% urethane dimethacrylate (UDMA), 15 wt% of glycerol-1,3-dimethacrylate (GDMA), 15 wt% of ethoxylated bisphenol A glycol dimethacrylate (BISEMA), camphorquinone (CQ), N,N-dihydroxyethyl-para-toluidine (DHEPT), and benzoyl-peroxide. 10 wt% of each HAp, α-TCP, or OCP were added to the resin and its properties were assessed. RESULTS: After 7 days, the degree of conversion ranged from 44.69% (GOCP) to 50.74% (Gcontrol) and no statistical difference were observed (p < 0.05). GAHplus showed the highest push-out bond strength 4.91 (± 2.38) MPa at 28 days of analysis (p < 0.05). Film thickness and pH were not statistically different (p > 0.05). Statically lower values of flow were found for GHAp, GOCP, and Gα-TCP (p < 0.05). Calcium deposition values were higher for GHAp at 28 days. CONCLUSIONS: Bond strength, degree of conversion, and film thickness of endodontic sealers with phosphates showed similar results compared with AHplus, but displayed higher amounts of Ca2+ release. CLINICAL RELEVANCE: Phosphate fillers improve the performance of endodontic sealers after 28 days of simulated body fluid.


Assuntos
Fosfatos de Cálcio , Metacrilatos , Materiais Restauradores do Canal Radicular , Fosfatos de Cálcio/química , Fosfatos de Cálcio/farmacologia , Humanos , Teste de Materiais , Metacrilatos/química , Metacrilatos/farmacologia , Materiais Restauradores do Canal Radicular/química , Materiais Restauradores do Canal Radicular/farmacologia , Obturação do Canal Radicular
16.
Braz Oral Res ; 33: e012, 2019 Feb 11.
Artigo em Inglês | MEDLINE | ID: mdl-30758409

RESUMO

The aim of this study was to investigate the mechanical performance and the fracture behavior of endocrown restorations prepared using distinct restorative materials. A total of 42 sound molars with similar crown size and shape were cut at 2 mm above the cementoenamel junction and endodontically treated. They were categorized according to the restorative material used to fabricate endocrown restorations (n=7), namely, conventional composite (Filtek™ Z350 XT), bulk fill composite (Filtek™ Bulk Fill), conventional composite modeled using resin adhesives (SBMP: Scotchbond™ Multipurpose Adhesive; or SBU: Scotchbond™ Universal Adhesive), and IPS e.max lithium disilicate (Ivoclar Vivadent; positive control). Unprepared sound teeth were used as negative control. All endocrowns were bonded using a self-adhesive cement (Rely-X™ U200). The teeth were submitted to fatigue (Byocycle) and fracture (EMIC DL500) testing. Load-to-fracture (in N) and work-of-fracture (Wf, in J/m2) values were analyzed by ANOVA (p < 0.05). The endocrowns did not fracture or de-bond upon fatigue, showing similar load-to-fracture and work-of-fracture values, regardless of the restorative material (p > 0.05). The endocrowns fabricated by combining Z350 and SBMP had the least harsh fractures, in contrast to endocrowns prepared using Z350 only, which exhibited an equilibrium between repairable and irrepairable fractures. The e.max endocrowns exhibited more aggressive failures (root fracture) than other groups, resulting in higher rates of irrepairable fractures. In conclusion, dental practitioners may satisfactorily restore severely damaged nonvital teeth using the endocrown technique. Composite endocrowns prepared using resin adhesive as modeler liquid or using bulk fill material may result in less aggressive failures, thus providing a new material perspective for endocrown restorations.


Assuntos
Resinas Compostas/química , Coroas , Restauração Dentária Permanente/métodos , Adesivos Dentinários/química , Cimentos de Resina/química , Porcelana Dentária/química , Planejamento de Prótese Dentária , Falha de Restauração Dentária , Análise do Estresse Dentário , Humanos , Teste de Materiais , Valores de Referência , Reprodutibilidade dos Testes , Materiais Restauradores do Canal Radicular/química , Fraturas dos Dentes , Dente não Vital
17.
Int Endod J ; 52(2): 250-257, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30091141

RESUMO

AIM: To compare the efficiency of M-Wire Reciproc and Reciproc Blue instruments in the removal of root filling material and in their ability to regain apical patency through micro-computed tomographic (micro-CT) analysis. METHODOLOGY: Ten anatomically matched pairs of teeth, with a single oval-shaped straight canal, were selected and scanned in a micro-CT device. The root canals were prepared with M-Wire Reciproc R25 instruments and filled with gutta-percha and AH Plus sealer. The root canals were then randomly allocated into two groups (n = 10), according to the instrument used: M-Wire Reciproc and Reciproc Blue. The canals were retreated up to instrument sizes 25 and then 40 in both groups. The surface area and volume of residual filling material were assessed using micro-CT imaging after the retreatment procedures. The time required to remove the root fillings was recorded. Data were analysed statistically using t-test with a significance level of 5%. RESULTS: No significant difference (P > 0.05) was observed between the instruments in terms of the volume of residual root filling material. Apical enlargement from size 25 to 40 significantly improved the removal of filling materials (P < 0.05). It was possible to regain apical patency in all specimens from both M-Wire Reciproc and Reciproc Blue groups. No difference was observed in the time required to perform the retreatment between the instruments. CONCLUSIONS: Both M-Wire Reciproc and Reciproc Blue instruments were effective in removing filling materials from oval-shaped straight canals. Apical patency was reestablished in all specimens.


Assuntos
Instrumentos Odontológicos , Materiais Restauradores do Canal Radicular/química , Obturação do Canal Radicular/instrumentação , Obturação do Canal Radicular/métodos , Preparo de Canal Radicular/instrumentação , Preparo de Canal Radicular/métodos , Anatomia Transversal , Ligas Dentárias/química , Cavidade Pulpar/diagnóstico por imagem , Desenho de Equipamento , Guta-Percha/química , Humanos , Incisivo/anatomia & histologia , Incisivo/diagnóstico por imagem , Incisivo/cirurgia , Mandíbula , Teste de Materiais , Níquel/química , Retratamento , Irrigantes do Canal Radicular , Hipoclorito de Sódio/química , Propriedades de Superfície , Titânio , Ápice Dentário/anatomia & histologia , Microtomografia por Raio-X/métodos
18.
Int Endod J ; 52(3): 377-384, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30193002

RESUMO

AIM: To compare the effect of furcal perforations of various sizes on the biomechanical response of mandibular first molars with or without periodontal bone loss at the furcal region via three-dimensional (3D) finite element analysis (FEA). METHODOLOGY: The 3D geometric basic model was reconstructed from the micro-computed tomographic images of an extracted mandibular first molar. Five different models were constructed from this molar in group 1 as follows: intact molar model, root filled (RCF) model and three models with furcal perforations (1, 2 and 3 mm in diameter) repaired with a calcium silicate-based cement (CSC). In group 2, a lesion simulating bone resorption at the furcal region was modelled on the models in group 1. A force of 200 N was applied to simulate normal occlusal loads. Static linear FEA was performed using the Abaqus software (Abaqus 6.14; ABAQUS Inc., Providence, RI, USA). The maximum principal stresses (Pmax ) and maximum displacement magnitude were evaluated. RESULTS: The range of Pmax values of the models in group 1, from high to low, was as follows: RCF + 3 mm perforation > RCF + 2 mm perforation > RCF + 1 mm perforation > RCF > intact model, and the range of Pmax values of the models in group 2 was as follows: RCF + 3 mm perforation + furcal lesion > RCF + 2 mm perforation + furcal lesion > RCF + 1 mm perforation + furcal lesion > RCF + furcal lesion > intact model + furcal lesion. All of the models in group 2 exhibited lower Pmax values and higher maximum displacement magnitude than their counterparts without lesions in group 1. CONCLUSIONS: The size of the furcal perforation affected the accumulation and distribution of stress within the models. Mandibular molar teeth with large furcal perforations treated with a calcium silicate-based cement may be associated with an increased risk of fracture whether or not accompanied by bone resorption.


Assuntos
Defeitos da Furca/diagnóstico por imagem , Defeitos da Furca/fisiopatologia , Dente Molar/diagnóstico por imagem , Fenômenos Biomecânicos , Compostos de Cálcio/química , Análise do Estresse Dentário , Análise de Elementos Finitos , Defeitos da Furca/terapia , Humanos , Mandíbula/diagnóstico por imagem , Materiais Restauradores do Canal Radicular/química , Silicatos/química , Software , Microtomografia por Raio-X
19.
J Prosthodont ; 28(1): e222-e228, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-28872730

RESUMO

PURPOSE: To evaluate microleakage in roots restored with fiber posts cemented using three different luting cements, to measure the volume of voids/gaps within the obturated/postcemented root canals, and to examine whether microleakage and the volume of voids/gaps were correlated. MATERIALS AND METHODS: Thirty-six extracted human mandibular incisors were decoronated, and the root canals were obturated using gutta-percha and sealer in the experimental groups (n = 30). Six roots were used as controls. A standard post space was prepared, and an identically sized fiber post was cemented in each experimental specimen using one of three luting cements (Panavia F2.0, Bifix SE, GC FujiCEM; n = 10 each). The specimens were scanned using micro-computed tomography, and the volume of voids/gaps was determined. The specimens were then subjected to a fluid filtration assay to evaluate microleakage. RESULTS: The volume of voids/gaps was significantly lower in the GC FujiCEM group, and significantly less microleakage occurred in the Bifix SE group compared with other groups (both p < 0.001). A significant correlation between the volume of voids/gaps and leakage was found only in the Panavia F2.0 group (p = 0.003; r = 0.830). No such correlation was found in the analysis of all groups combined. CONCLUSIONS: The group with the greatest volume of voids/gaps (Bifix SE) showed the least microleakage, and the group with the smallest volume of voids/gaps (GC FujiCEM) showed the most microleakage. Panavia F2.0 ranked between and exhibited significant correlation.


Assuntos
Cimentação/métodos , Cimentos Dentários/química , Infiltração Dentária , Técnica para Retentor Intrarradicular , Materiais Restauradores do Canal Radicular/química , Colagem Dentária , Infiltração Dentária/prevenção & controle , Materiais Dentários/química , Cavidade Pulpar/diagnóstico por imagem , Adesivos Dentinários/química , Vidro , Cimentos de Ionômeros de Vidro/química , Guta-Percha , Humanos , Hidroxibenzoatos , Incisivo , Teste de Materiais , Nitrofuranos , Cimentos de Resina , Obturação do Canal Radicular , Tratamento do Canal Radicular/métodos , Microtomografia por Raio-X
20.
Clin Oral Investig ; 23(1): 43-52, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29603021

RESUMO

OBJECTIVE: The objective of this study was to analyze the microstructure and crystalline structures of ProRoot MTA, Biodentine, CEM Cement, and Retro MTA when exposed to phosphate-buffered saline, butyric acid, and blood. METHODS AND MATERIALS: Mixed samples of ProRoot MTA, Biodentine, CEM Cement, and Retro MTA were exposed to either phosphate-buffered saline, butyric acid, or blood. Scanning electron microscope (SEM) and energy-dispersive X-ray spectroscopic (EDX) evaluations were conducted of specimens. X-ray diffraction (XRD) analysis was also performed for both hydrated and powder forms of evaluated calcium silicate cements. RESULTS: The peak of tricalcium silicate and dicalcium silicate detected in all hydrated cements was smaller than that seen in their unhydrated powders. The peak of calcium hydroxide (Ca(OH)2) in blood- and acid-exposed ProRoot MTA, CEM Cement, and Retro MTA specimens were smaller than that of specimens exposed to PBS. The peak of Ca(OH)2 seen in Biodentine™ specimens exposed to blood was similar to that of PBS-exposed specimens. On the other hand, those exposed to acid exhibited smaller peaks of Ca(OH)2. CONCLUSION: Exposure to blood or acidic pH decreased Ca(OH)2 crystalline formation in ProRoot MTA, CEM Cement and Retro MTA. However, a decrease in Ca(OH)2 was only seen when Biodentine™ exposed to acid. CLINICAL RELEVANCE: The formation of Ca(OH)2 which influences the biological properties of calcium silicate cements was impaired by blood and acid exposures in ProRoot MTA, CEM Cement, and Retro MTA; however, in the case of Biodentine, only exposure to acid had this detrimental effect.


Assuntos
Compostos de Cálcio/química , Cimentos Dentários/química , Silicatos/química , Sangue , Ácido Butírico , Combinação de Medicamentos , Concentração de Íons de Hidrogênio , Teste de Materiais , Microscopia Eletrônica de Varredura , Óxidos/química , Compostos de Fósforo/química , Materiais Restauradores do Canal Radicular/química , Solução Salina , Espectrometria por Raios X , Propriedades de Superfície , Difração de Raios X
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