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1.
Braz. j. oral sci ; 21: e224977, jan.-dez. 2022. ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1354723

RESUMO

Aim: This study aims to evaluate the clinical assessment results of periimplant soft tissue with morse taper (internal abutment connection). Methods: The study was conducted using a rapid review by searching the articles from PubMed NCBI and Cochrane by using keywords. All articles were selected by the year, duplication, title, abstract, full-text, and finally, all selected articles were processed for final review. Following clinical parameters were included; Periimplant Probing Pocket Depth (PPD), Plaque Score (PS), modified Plaque Index (mPI), Mucosal Thickness (MTh), Gingival Height (GH), periimplant mucosal zenith, Pink Esthetic Score (PES), Bleeding On Probing (BOP), Sulcus Bleeding Index (SBI), and modified Gingival Index (mGI). Results: 9 selected articles were obtained from the initial literature searching count of 70 articles. The overall samples included 326 morse taper implants. Based on the evaluation, 3 out of 4 articles reported pocket depth < 4 mm, no bleeding was reported in 2 out of 4 articles. 4 out of 4 articles reported low plaque accumulation, low soft tissue recession was reported in 3 out of 3 articles, and 4 out of 4 articles reported acceptable PES values. Conclusion: The evaluations indicate that the morse taper (internal abutment connection) has favorable assessment results based on various clinical parameters


Assuntos
Implantes Dentários , Dente Suporte , Lesões dos Tecidos Moles , Projeto do Implante Dentário-Pivô , Gengiva , Mucosa Bucal
2.
Braz. j. oral sci ; 21: e226427, jan.-dez. 2022. ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1393274

RESUMO

Aim: This study aimed to investigate whether non-ionizing radiation emitted by smartphones is likely to cause genotoxic effects on oral epithelial cells. Methods: Thirty adults were distributed into two groups according to the mobile phone brand used, namely Samsung (Samsung, Seoul, South Korea) and Apple (Apple, California, USA). The material was collected with gentle swabbing of the right and left buccal mucosa using a cervical brush, then the micronucleus test was performed. Results: The Mann-Whitney test with a 5% significance level did not reveal statistically significant differences in micronuclei frequency between the exposed and non-exposed sides (p=0.251). The different brands do not seem to cause risks of inducing genetic damage because there were no statistically significant differences between them (p=0.47). Conclusion: Therefore, our results suggest no correlations of micronuclei frequency in the exposed buccal cells of mobile phone users at the exposure standard levels observed


Assuntos
Humanos , Masculino , Feminino , Adulto , Radiação não Ionizante/efeitos adversos , Ondas de Rádio , Testes para Micronúcleos , Células Epiteliais , Smartphone , Mucosa Bucal , Testes de Mutagenicidade
3.
Rev. Odontol. Araçatuba (Impr.) ; 43(3): 33-39, set.-dez. 2022. tab
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-1381093

RESUMO

O presente estudo aborda os protocolos odontológicos instituídos na Unidade de Terapia Intensiva COVID de um Hospital do Extremo Sul Catarinense. A cavidade oral, considerada uma abertura para a entrada de microrganismos, possui características favoráveis ao seu crescimento, com temperatura e umidade ideais para sua sobrevivência em longo prazo. A odontologia, por manipular diretamente mucosa oral, fica exposta e vulnerável ao contágio do COVID-19, assim como a equipe multiprofissional que manipula o paciente nas diversas áreas de atenção à saúde, no ambiente hospitalar. A COVID-19 é uma infecção respiratória aguda causada pelo coronavírus SARS-CoV-2, potencialmente grave, de elevada transmissibilidade e de distribuição global. A maioria das pessoas (cerca de 80%) se recupera da doença sem precisar de tratamento hospitalar. Uma em cada seis pessoas infectadas por COVID-19 fica gravemente doente e desenvolve dificuldade de respirar. As pessoas idosas e as que têm outras condições de saúde, como pressão alta, problemas cardíacos e do pulmão, diabetes ou câncer, têm maior risco de ficarem gravemente doentes. No entanto, qualquer pessoa pode pegar a COVID-19 e ficar gravemente doente. Constatou-se que a aplicação de protocolos odontológicos na Unidade de Terapia Intensiva apresenta uma série de vantagens em relação à prevenção da contaminação dos profissionais de saúde, à manutenção da saúde bucal do paciente, aos benefícios gerais para a saúde, à prevenção e ao tratamento de infecções oportunistas, que podem reduzir o tempo de internação do paciente, pois infecção generalizada e pneumonia são doenças nosocomiais também causadas por distúrbios na microbiota oral. Os resultados mostraram que não há cirurgiões dentistas atuando na Unidade de Terapia Intensiva, os protocolos não são específicos para área de odontologia e os equipamentos de proteção individuais são utilizados, porém, não em todos atendimentos(AU)


The present study addresses the dental protocols established in the COVID Intensive Care Unit of a Hospital in Extremo Sul Santa Catarina. The oral cavity, considered an opening for the entry of microorganisms, has characteristics favorable to its growth, with ideal temperature and humidity for its long-term survival. Dentistry, by directly manipulating the oral mucosa, is exposed and vulnerable to COVID-19 contagion, as well as the multidisciplinary team that handles the patient in the different areas of health care, in the hospital environment. COVID-19 is a potentially serious acute respiratory infection caused by the SARS-CoV-2 coronavirus, with high transmissibility and global distribution. Most people (about 80%) recover from the disease without needing hospital treatment. One in six people infected with COVID-19 becomes seriously ill and develops difficulty breathing. Elderly people and those with other health conditions, such as high blood pressure, heart and lung problems, diabetes or cancer, are at increased risk of becoming seriously ill. However, anyone can take COVID-19 and become seriously ill. It was found that the application of dental protocols in the Intensive Care Unit has a number of advantages in relation to the prevention of contamination of health professionals, the maintenance of the patient's oral health, the general benefits for health, prevention and treatment of opportunistic infections, which can reduce the patient's hospital stay, as generalized infection and pneumonia are nosocomial diseases also caused by disorders in the oral microbiota. The results showed that there are no dentists working in the Intensive Care Unit, the protocols are not specific to the field of dentistry and individual protective equipment is used, however, not in all cases(AU)


Assuntos
Odontólogos , COVID-19 , Unidades de Terapia Intensiva , Equipe de Assistência ao Paciente , Saúde Bucal , Transmissão de Doença Infecciosa , Tempo de Internação , Mucosa Bucal
4.
Artigo em Inglês | MEDLINE | ID: mdl-36360656

RESUMO

The purpose of this article was to evaluate reported oral and mucosal complaints among seniors residing in institutionalized 24-h care of the Municipal Center for Older and Dependent People (MHCOD) and the 3-month rehabilitation program of the Daily Medical Care House (DMCH). We evaluated the feasibility of using the dental mirror slidding test to assess dry mouth of seniors. Patients underwent a questionnaire, and clinical examination. The Visual Analogue Scale (VAS) was used to assess pain, Fox's questionnaire and Challacombe's scale with Clinical Oral Dryness Score to assess dryness of the mouth, dental mirror slidding test to assess buccal mucosal resistance. Dryness, mucosal burning, impaired taste, food intake are symptoms associated with seniors, and their frequency does not depend on the type of care. The incidence of mucosal burning (Mdn = 4.0, IQR = 4.75, p = 0.032) and difficulty in using dental prosthetics (Mdn = 3.0, IQR = 4.00, p = 0.010) increase with the length of stay at MHCOD. Seniors are at risk of side effects of polypharmacy, which cause dryness (p = 0.036), complaints of lack of saliva (p = 0.009) and taste disorders (p = 0.041. Seniors with higher levels of dry mouth are more likely to exhibit mucosal burning (p = 0.026) and difficulty in taking food (p = 0.037). The implementation of the dental mirror slidding test in the scope of the primary care of geriatric examination should be discussed.


Assuntos
Xerostomia , Humanos , Idoso , Saliva , Mucosa Bucal , Inquéritos e Questionários
5.
Zhonghua Wai Ke Za Zhi ; 60(11): 981-986, 2022 Nov 01.
Artigo em Chinês | MEDLINE | ID: mdl-36323579

RESUMO

Urethroplasty is an important method to treat male urethral stricture. Nowadays, urethroplasty mainly includes two types: anastomotic urethroplasty and substitution urethroplasty. Anastomotic urethroplasty mainly includes primary anastomosis urethroplasty and non-transecting anastomotic urethroplasty. Substitution of urethroplasty mainly includes staged urethroplasty and one-stage urethroplasty. Substitution materials always are chosen by pedicle skin flap and free mucosal graft. Anastomosis urethroplasty has shown good results in short bulbar urethral stricture and posterior urethral stricture after pelvic fracture. Among them, non-transecting anastomosis urethroplasty has become a new surgical method for iatrogenic, single, short or non-occluded stenosis. At present, the one-stage substitution urethroplasty is the most widely used. However, there are still many complicated cases that must be solved by staged urethroplasty. Pedicle skin flap and oral mucosa are widely used as substitutes at present. How to select the best surgical procedure and substitute materials individually would be the problem worthy of attention in the future. Accumulating more long-term follow-up data is helpful for objective comparison of various surgical procedures and grafts.


Assuntos
Estreitamento Uretral , Procedimentos Cirúrgicos Urológicos Masculinos , Humanos , Masculino , Mucosa Bucal/transplante , Retalhos Cirúrgicos , Estreitamento Uretral/cirurgia , Procedimentos Cirúrgicos Urológicos Masculinos/métodos , Resultado do Tratamento
6.
Front Immunol ; 13: 1020768, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36389753

RESUMO

The oral mucosa is a membranous structure comprising epithelial and connective tissue that covers the oral cavity. The oral mucosa is the first immune barrier to protect the body against pathogens for systemic protection. It is frequently exposed to mechanical abrasion, chemical erosion, and pathogenic invasion, resulting in oral mucosal lesions, particularly inflammatory diseases. Epithelial-mesenchymal transition (EMT) is a crucial biological process in the pathogenesis of oral mucosal disorders, which are classified into three types (types 1, 2, and 3) based on their physiological consequences. Among these, type-2 EMT is crucial in wound repair, organ fibrosis, and tissue regeneration. It causes infectious and dis-infectious immunological diseases, such as oral lichen planus (OLP), oral leukoplakia, oral submucosal fibrosis, and other precancerous lesions. However, the mechanism and cognition between type-2 EMT and oral mucosal inflammatory disorders remain unknown. This review first provides a comprehensive evaluation of type-2 EMT in chronically inflammatory oral mucosal disorders. The aim is to lay a foundation for future research and suggest potential treatments.


Assuntos
Líquen Plano Bucal , Doenças da Boca , Lesões Pré-Cancerosas , Humanos , Transição Epitelial-Mesenquimal , Doenças da Boca/patologia , Líquen Plano Bucal/patologia , Mucosa Bucal/patologia
7.
Front Immunol ; 13: 1009742, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36389752

RESUMO

Oral inflammatory diseases, including oral lichen planus (OLP) and recurrent aphthous ulcer (RAU), seriously affect the patient's quality of life. Due to the lack of ideal disease models, it is difficult to determine whether novel immunotherapy strategies are effective in treating oral inflammatory diseases. Here, we show that the deficiency of Foxp3 or IL-2 caused oral mucosa inflammation in mice, proving that Treg cells are important in maintaining the immune homeostasis in the oral mucosa. Then we determined that adoptive transfer of CD4+CD25-CD45Rbhigh T cells could induce oral inflammation in Rag1 -/- mice, and co-transfer of Treg cells together with CD4+CD25-CD45Rbhigh T cells could suppress the development of oral inflammation in this mouse model. Our study showed that adoptive transfer of CD4+CD25-CD45Rbhigh T cells into Rag1 -/- mice could be a novel disease model of oral inflammation. Our data provides direct evidence that Treg cell therapy is effective in suppressing oral mucosa inflammation in mice. Therefore, Treg cell therapy may be a promising novel strategy to treat oral inflammatory diseases.


Assuntos
Mucosa Bucal , Linfócitos T Reguladores , Camundongos , Animais , Fatores de Transcrição Forkhead/genética , Qualidade de Vida , Inflamação/terapia , Proteínas de Homeodomínio/genética
8.
BMC Oral Health ; 22(1): 514, 2022 Nov 19.
Artigo em Inglês | MEDLINE | ID: mdl-36402984

RESUMO

BACKGROUND: Erosion is one of the most common and basic lesions of oral mucosal diseases. Long-term refractory oral erosions, induced by autoimmune blistering diseases, infectious diseases, malignant diseases, and some rare conditions, may substantially reduce the quality of life of patients or even constitute a life-threatening condition, resulting in a clinical dilemma regarding the accurate diagnosis and precise management of these diseases. As a special type of malignant lymphoma, most lesions of follicular lymphoma (FL) in the oral mucosa present as masses or swelling of the oral mucosa, while emerging novel presentations lead to intractable diagnoses. Hence, diagnostic algorithms for such diseases are clinically required.  CASE PRESENTATION: A 55-year-old female patient presented to the clinic with long-lasting oral mucosal erosions and proliferative lesions. Blood tests, pathological examinations of oral lesions including haematoxylin-eosin (HE) staining, and direct immunofluorescence precluded all of the potential diagnoses described previously. Unexpectedly, positron emission tomography/computed tomography (PET/CT) and abdominal CT of the patient revealed a dense mass in the retroperitoneal area, and the final diagnosis of the retroperitoneal mass was FL. After three courses of chemotherapy conducted by the haematologist, the erosion and proliferative lesions in the patient's oral mucosa had significantly improved. HE and immunohistochemical staining results of intraoral lesions also confirmed it as oral FL. The successful diagnosis of FL in this case is of great clinical significance, as the oral and abdominal FL were treated in a timely manner to avoid unfavourable outcomes. CONCLUSIONS: To the best of our knowledge, this is the first case of FL that exhibited widespread erosions interspersed with proliferative lesions. Clinicians should be aware of oral FL or seek systemic factors in the presence of similar refractory oral erosions when treatment is non-responsive and the diagnosis is intractable.


Assuntos
Linfoma Folicular , Doenças da Boca , Humanos , Feminino , Pessoa de Meia-Idade , Linfoma Folicular/diagnóstico , Linfoma Folicular/tratamento farmacológico , Linfoma Folicular/patologia , Mucosa Bucal/patologia , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Qualidade de Vida , Doenças da Boca/diagnóstico , Doenças da Boca/terapia
9.
Nutrients ; 14(21)2022 Nov 04.
Artigo em Inglês | MEDLINE | ID: mdl-36364938

RESUMO

Fatty acids exert a range of different biological activities that could be relevant in the development of atopic dermatitis (AD). This study investigated the association of glycerophospholipid fatty acids (GPL-FA) with AD, and their interactions with single nucleotide polymorphisms (SNP) of the FADS1-3 gene cluster. Among 390 infants of the Indonesian ISADI study, GPL-FA were measured in umbilical plasma (P-0y) and in buccal cells at birth (B-0y), and again in buccal cells at AD onset or one year (B-1y). Prospective and cross-sectional associations with AD were assessed by logistic regression. Interactions of GPL-FA with 14 SNP were tested assuming an additive model. AD was diagnosed in 15.4% of participants. In B-1y, C18:2n-6 was inversely associated with AD; and positive associations were observed for C18:1n-9, C20:4n-6, C22:6n-3 and C20:4n-6/C18:2n-6. There were no prospective associations with AD, however, a significant interaction between the SNP rs174449 and B-0y C14:0 (myristic acid) was observed. This study indicates that Indonesian infants with AD have increased rates of endogenous long-chain polyunsaturated fatty acid production, as well as higher C18:1n-9 levels. GPL-FA measured at birth do not predict later AD incidence; however, genotype interactions reveal novel effects of myristic acid, which are modified by a FADS3 variant.


Assuntos
Dermatite Atópica , Lactente , Recém-Nascido , Humanos , Dermatite Atópica/genética , Estudos Transversais , Ácido Mirístico , Indonésia/epidemiologia , Mucosa Bucal , Ácidos Graxos , Glicerofosfolipídeos , Ácidos Graxos Dessaturases/genética
10.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 40(6): 721-726, 2022 Dec 01.
Artigo em Inglês, Chinês | MEDLINE | ID: mdl-36416327

RESUMO

Radiation-induced oral mucositis is an oral mucosal injury caused by radiation ionizing radiation, which often manifests as oral mucosal congestion, erosion, and ulcers. Radiation-induced oral mucositis manifesting as vascular proliferative changes in the oral mucosa has not been reported. We report a case of oral mucosal atypical vascular proliferation after radiotherapy for a malignant maxillofacial tumor. We discussed the mechanism and treatment of aty-pical vascular proliferation in the oral mucosa secondary to radiotherapy, including diagnosis, treatment, and previous literature.


Assuntos
Neoplasias , Lesões por Radiação , Estomatite , Humanos , Estomatite/etiologia , Estomatite/patologia , Estomatite/terapia , Mucosa Bucal , Neoplasias/complicações , Proliferação de Células
11.
Malawi Med J ; 34(3): 204-205, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-36406096

RESUMO

Angina bullosa haemorrhgica is a relatively uncommon condition characterized by blood-filled subepithelial lesions in the oral mucosa that is idiopathic and not caused by a systemic disease or a hemostatic abnormality. Middle-aged and elderly patients are usually affected and lesions heal spontaneously without scarring. A rapidly expanding hemorrhagic blister in the oropharynx can induce upper airway obstruction, so recognizing the lesion as soon as possible is essential. Because of its rarity, we wanted to highlight a 42-year-old male patient who presented with hemorrhagic bullae associated with insignificant local trauma in the oral mucosa and to emphasize that Angina bullosa haemorrhagica is a rare but recognizable lesion that clinicians should be aware of.


Assuntos
Vesícula , Mucosa Bucal , Pessoa de Meia-Idade , Idoso , Masculino , Humanos , Adulto , Mucosa Bucal/lesões , Mucosa Bucal/patologia , Vesícula/etiologia , Vesícula/patologia
12.
Georgian Med News ; (328-329): 127-132, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36318856

RESUMO

The impact of SARS-CoV-2 (severe acute respiratory syndrome-related coronavirus-2) on the entire human body causes irreversible changes in all organs and systems. Complications in the form of chronic diseases require the treatment of clinicians in various fields of medicine. Dentists are faced with diseases of the oral mucosa in apparently healthy patients who are not predisposed to them but have undergone COVID-19. Purpose of the study - to assess the impact of the coronavirus infection (COVID-19) on the course of diseases of the oral mucosa. We examined 51 patients aged 20 to 75 who had undergone COVID-19 with various diseases of the oral mucosa. The study used clinical and laboratory methods. The features of the clinical course of certain diseases of the oral mucosa were revealed, the dynamics of the local immune defense of the oral cavity in the post-covid period was determined.


Assuntos
COVID-19 , SARS-CoV-2 , Humanos , Mucosa Bucal
13.
Genes (Basel) ; 13(10)2022 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-36292660

RESUMO

Each year approximately 1 million total hip replacements are performed worldwide. The most common indications to choose this procedure are rest pain and pain after activity as well as functional limitations influencing daily activities. Experimental pain is highly variable by individuals, which is partly due to genetics. The aim of the study was to investigate a possible association of the catechol-O-methyltransferase (COMT) and µ-opioid receptor (OPRM1) genotypes with pain perception in patients undergoing total hip replacement and total knee replacement taking into account aspects such as age, sex and diabetes. The study included 207 patients (119 females, 88 males, median age 65 years, range 33-77) that qualified for surgical treatment (total hip replacement and knee arthroplasty) due to osteoarthritis. Pain sensitivity measurement was performed using a standard algometer. The genomic DNA was extracted from the buccal cells.. Single locus analysis was conducted using a general linear model. In the study group, we did not find statistically significant genetic associations between variants of COMT and OPRM1 and pain thresholds/pain tolerance. The analysis of subjective pain perception using the visual analog scale did not show any relationship between the OPRM1 rs1799971A&gt;G variant and COMT rs4680, rs4633, rs4818 and rs6269.


Assuntos
Artroplastia do Joelho , Osteoartrite , Masculino , Feminino , Humanos , Adulto , Pessoa de Meia-Idade , Idoso , Catecol O-Metiltransferase/genética , Mucosa Bucal , Polimorfismo de Nucleotídeo Único , Percepção da Dor , Dor/genética , Receptores Opioides mu/genética
14.
Sci Rep ; 12(1): 17527, 2022 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-36266464

RESUMO

Oral mucositis (OM) is a complex acute cytotoxicity of antineoplastic treatment that affects 40-85% of patients undergoing hematopoietic stem-cell transplantation. OM is associated with prolonged hospitalization, increased extensive pharmacotherapy, need for parenteral nutrition, and elevated treatment costs. As OM onset relates to the mucosal microenvironment status, with a particular role for microbiota-driven inflammation, we aimed to investigate whether the oral mucosa microbiota was associated with the clinical course of OM in patients undergoing allogeneic hematopoietic stem-cell transplantation. We collected oral mucosa samples from 30 patients and analyzed the oral mucosa microbiota by 16S rRNA sequencing. A total of 13 patients (43%) developed ulcerative OM. We observed that specific taxa were associated with oral mucositis grade and time to oral mucositis healing. Porphyromonas relative abundance at preconditioning was positively correlated with ulcerative OM grade (Spearman ρ = 0.61, P = 0.028) and higher Lactobacillus relative abundance at ulcerative OM onset was associated with shortened ulcerative OM duration (P = 0.032). Additionally, we generated a machine-learning-based bacterial signature that uses pre-treatment microbial profiles to predict whether a patient will develop OM during treatment. Our findings suggest that further research should focus on host-microbiome interactions to better prevent and treat OM.


Assuntos
Transplante de Células-Tronco Hematopoéticas , Microbiota , Estomatite Aftosa , Estomatite , Humanos , RNA Ribossômico 16S/genética , Estomatite/microbiologia , Transplante de Células-Tronco Hematopoéticas/efeitos adversos , Mucosa Bucal/microbiologia
15.
Stomatologiia (Mosk) ; 101(5): 68-72, 2022.
Artigo em Russo | MEDLINE | ID: mdl-36268924

RESUMO

A clinical example of the manifestation of vulgar pemphigus on the oral mucosa in the form of a single mildly painful erosion at the border of the soft and hard palate with extensive erosive lesions that existed in the patient for a long time is presented. The detection of a false positive reaction to syphilis led to an increase in the time of diagnosis. Only the appointment of a repeated full examination of the patient in accordance with clinical standards (cytological analysis, histological examination and indirect immunofluorescence method) allowed to establish the correct diagnosis, prescribe adequate therapy to the patient in a hospital setting and get a positive result.


Assuntos
Pênfigo , Humanos , Mucosa Bucal/patologia , Pênfigo/diagnóstico , Pênfigo/tratamento farmacológico , Pênfigo/patologia
16.
Front Immunol ; 13: 1001970, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36263026

RESUMO

Oral lichen planus (OLP) is an inflammatory disease of the oral mucosa. Clinically, two main subsets are described, namely non-erosive and erosive OLP. While non-erosive OLP is usually responsive to local therapies, erosive OLP is often refractory also to systemic therapies and extremely reduces the quality of life of the patients. Furthermore, in some erosive OLP cases different autoantibodies have been detected, including anti-desmoglein 1 and 3 autoantibodies, and anti-bullous pemphigoid 180 and 230 autoantibodies. However, their potential role is still not clear. In this paper, we reviewed the literature about the detection of autoantibodies against desmoglein 1 and 3, the main target antigens of pemphigus vulgaris, in patient with OLP, summarizing the more recent insights on this topic.


Assuntos
Líquen Plano Bucal , Pênfigo , Humanos , Líquen Plano Bucal/diagnóstico , Qualidade de Vida , Mucosa Bucal , Autoanticorpos , Pênfigo/diagnóstico , Pênfigo/tratamento farmacológico
18.
Microsc Res Tech ; 85(12): 3793-3803, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36260813

RESUMO

The study aimed to explore the ultrastructure of the donkeys' palatine tonsils. Palatine tonsils of five male donkeys (5 years old) were investigated macroscopically and microscopically. The tonsils appeared as a dome shape with slight elevation and a circular opening on the surface of the oropharynx. The central tonsillar crypt appeared on the medial side of the palate-pharyngeal folds and the floor of the oropharynx. The external surface of the palatine tonsil had different sizes of mucosal folds, some grooves directed to drainage at the tonsillar opening, and the tonsil crypt opening was a crescentic or irregular oval shape. The outer surface was covered by stratified squamous epithelium and modified to be reticular epithelium invaded by lymphocytes in the crypt called lympho-epithelium. The tonsil crypt had aggregated lymphoid nodules, and the cryptal epithelium has surrounded by diffused lymphocytes and hassles corpuscles-like structures. The lymphocytes infiltrated into different layers of the cryptal epithelium and transformed into reticular or lympho-epithelium. The organized lymphoid nodules were primary and secondary, and the secondary ones had a light germinal center. The interfollicular area had many high endothelial venules and blood capillaries. The endothelial venules were lined by simple cuboidal epithelium and had lymphocytes. The blood capillaries had red blood cells and neutrophils. The tonsil was surrounded incompletely by a connective tissue capsule with mucous glands under that capsule. In conclusion, the epithelial lymphocyte infiltration, crypt epithelium, lymphoid nodules, and intra-follicular area of the donkey's palatine tonsils indicate the humoral and cell-mediated immunological process.


Assuntos
Equidae , Tonsila Palatina , Animais , Masculino , Tonsila Palatina/ultraestrutura , Microscopia Eletrônica de Transmissão , Epitélio/ultraestrutura , Mucosa Bucal , Microscopia Eletrônica de Varredura
19.
J Craniofac Surg ; 33(8): e869-e871, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36184761

RESUMO

At present, the most effective and common strategy to mobilize the maxilla is to use Rowe disimpaction forceps. But because of the directed forces on the hard palate, the mucosa of the hard palate will have to receive an ineluctable mechanical injury. Therefore, we introduce a novel forceps (Patent No. 202110966069.X China), which can accurately and steadily clamp the maxilla on the premise of protecting the hard palate mucosa from loss of palatal vascularity and pressure necrosis, and then thoroughly mobilize the maxilla. Complaints and mucosal damage were not observed in the initial 3 patients.


Assuntos
Maxila , Osteotomia de Le Fort , Humanos , Maxila/cirurgia , Palato Duro/cirurgia , Mucosa Bucal , Instrumentos Cirúrgicos
20.
Rev. esp. patol ; 55(4): 236-239, Oct-Dic. 2022. ilus
Artigo em Espanhol | IBECS | ID: ibc-210611

RESUMO

La paracoccidioidomicosis es una enfermedad crónica, sistémica y progresiva, identificada como la segunda micosis más común en Suramérica. Aproximadamente 10millones de habitantes latinoamericanos están infectados. Se encuentra con mayor frecuencia el compromiso pulmonar en hombres adultos agricultores. La paracoccidioidomicosis oral es la segunda forma más frecuente de evolución crónica. Presentamos el caso atípico de una paciente de mediana edad, inmunocompetente, con compromiso de la mucosa oral por infección con paracoccidio y una revisión breve acerca de la infección por paracoccidio en la cavidad oral.(AU)


Paracoccidioidomycosis is a progressive, chronic, systemic disease which is the second most common form of mycosis in South America, affecting approximately 10million people in this region. It occurs most commonly in adult male farmers and mainly affects the lungs. Oral paracoccidioidomycosis is the second most frequent chronic presentation. We report the case of an immunocompetent female patient whose oral mucosae was infected with paracoccidium and discuss oral paracoccidium.(AU)


Assuntos
Humanos , Feminino , Adulto , Paracoccidioidomicose/diagnóstico por imagem , Paracoccidioidomicose/etiologia , Patologia Bucal , Úlceras Orais , Mucosa Bucal , Pacientes Internados , Exame Físico , Biópsia , Pneumopatias Fúngicas , Patologia , Serviço Hospitalar de Patologia
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