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Ultrastruct Pathol ; 25(4): 321-33, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-11577778


Lipoblastoma is a relatively rare tumor that occurs in infancy and early childhood and arises from embryonic white fat. Although a benign tumor, lipoblastomas tend to recur and may resemble myxoid liposarcoma. The authors report 26 cases over a 15-year period at Texas Children's Hospital. There was a slight female predilection (14F:12M). The most common symptom was a painless mass with or without increasing size. The trunk, extremities, head and neck, retroperitoneum, inguinal canal, peritoneal cavity, and lung were the tumor sites. Most tumors were circumscribed lipoblastomas and the minority were diffuse infiltrative lipoblastomatosis. Reexcision for residual or recurrent tumor was necessary more frequently in patients with lipoblastomatosis. Histopathologic examination and ultrastructural examination revealed cellular neoplasms composed of immature adipocytes with relatively well-defined septa, frequent lipoblasts, a fine vascular network, and often a myxoid appearance resembling myxoid liposarcoma. Cytogenetics was performed in 4 cases with chromosome 8q abnormality being most common. The major concern with lipoblastoma in children is to completely excise the tumor to avoid leaving residual tumor and to prevent recurrences. Confusion with myxoid liposarcoma, well-differentiated liposarcoma, and typical lipomas may occur. Although asymptomatic, lipoblastomas may cause dysfunction of other organ systems due to mass effect. Complete surgical excision with at least 2 years of follow-up is the preferred therapy.

Neoplasias Lipomatosas/patologia , Neoplasias Lipomatosas/ultraestrutura , Fatores Etários , Criança , Pré-Escolar , Aberrações Cromossômicas/estatística & dados numéricos , Análise Citogenética , Grupos Étnicos , Feminino , Humanos , Lactente , Masculino , Microscopia Eletrônica , Metástase Neoplásica/patologia , Metástase Neoplásica/ultraestrutura , Recidiva Local de Neoplasia/epidemiologia , Neoplasias Lipomatosas/epidemiologia , Fatores Sexuais
Rev. Fac. Odontol. Bauru ; 4(3/4): 1-6, jul.-dez. 1996. ilus
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-222562


Um caso raro de lipoma intrabucal associado ao nervo mentoniano, causando sintomatologia dolorosa, assim como, uma revisäo de literatura mostrando a discutida etiopatogenia desta alteraçäo é apresentado

Humanos , Masculino , Adulto , Neoplasias Lipomatosas/diagnóstico , Neoplasias Lipomatosas/patologia , Neoplasias Lipomatosas/ultraestrutura , Adipócitos/patologia , Lipoma/diagnóstico , Lipoma/patologia , Lipoma/terapia , Lipoma/ultraestrutura , Nervo Maxilar/patologia , Neoplasias Lipomatosas/terapia