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Head Neck Pathol ; 10(4): 533-537, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27260217


A case of oral leishmaniasis without cutaneous involvement affecting the upper alveolar ridge mucosa/gingiva and the hard palate is reported in a 41-year-old Brazilian man. Microscopic examination disclosed scarce amastigotes and the definitive diagnosis was facilitated by immunohistochemical analysis. The clinical presentation of this lesion is unusual and underlies the importance of considering leishmaniasis in the differential diagnosis of oral lesions, especially in endemic areas. A literature review of the cases of mucosal leishmaniasis with exclusive primary lesions of the oral mucosa was also performed.

Leishmaniose/diagnóstico , Doenças da Boca/diagnóstico , Adulto , Humanos , Imuno-Histoquímica , Masculino , Mucosa Bucal/parasitologia , Palato Duro/parasitologia
Gerodontology ; 29(2): e1168-71, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22612832


INTRODUCTION: The term leishmaniasis comprises a group of diseases caused by different protozoan species of the genus Leishmania. There are three main clinical forms of leishmaniasis: visceral, cutaneous and mucocutaneous. Exclusive involvement of the mucosa is very rare. OBJECTIVES: To present a case of mucocutaneous leishmaniasis in an elderly patient, discuss the clinical presentation, diagnostic process and treatment emphasizing the distinctions from other granulomatous lesions. CASE REPORT: A 71-year-old male presenting with a symptomatic lesion on the hard and soft palate, which had developed over a period of 6 months was evaluated. The oral exam revealed a lesion with multiple ulcerated nodules on the hard and soft palate extending to the oropharynx. The diagnostic hypothesis was chronic infectious disease (paracoccidioidomycose, tuberculosis and leishmaniasis) or squamous cell carcinoma. Histopathological, histochemical and immunohistochemical analysis were performed. A chest x-ray revealed a normal pulmonary pattern. The Montenegro skin test was positive. The definitive diagnosis was leishmaniasis with exclusive oral manifestation and the patient was treated with liposomal amphotericin. CONCLUSIONS: Localized oral mucosa leishmaniasis is an uncommon event in an immunocompetent patient. Dentists play an important role in the diagnosis of oral leishmaniasis, which has systemic repercussions.

Leishmaniose/diagnóstico , Doenças da Boca/parasitologia , Idoso , Anfotericina B/uso terapêutico , Antiprotozoários/uso terapêutico , Carcinoma de Células Escamosas/diagnóstico , Diagnóstico Diferencial , Seguimentos , Humanos , Imuno-Histoquímica , Masculino , Doenças da Boca/microbiologia , Neoplasias Bucais/diagnóstico , Úlceras Orais/parasitologia , Palato Duro/parasitologia , Palato Mole/parasitologia , Paracoccidioidomicose/diagnóstico , Tuberculose Bucal/diagnóstico