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J Oral Pathol Med ; 49(4): 285, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32301541
Univ. salud ; 22(1): 70-76, ene.-abr. 2020. tab
Artigo em Espanhol | LILACS, COLNAL | ID: biblio-1094581


Introducción: El desarrollo de las Tecnologías de la Información y la Comunicación (TIC) y su fácil acceso, hacen de ésta una alternativa educativa que contribuye a incrementar la calidad de la educación, facilitando el proceso de enseñanza-aprendizaje con medios virtuales. Las lesiones elementales son alteraciones del tejido bucal y su conocimiento es importante para realizar un adecuado diagnóstico y manejo terapéutico. Objetivo: Diseñar, implementar y evaluar una aplicación móvil para la enseñanza de lesiones elementales en cavidad bucal. Materiales y métodos: Estudio de intervención, experimental, que evaluó una herramienta educativa sobre lesiones elementales bucales, utilizando una pre-prueba, una intervención y una prueba posterior, para el grupo control se evaluó el aprendizaje a través de la lectura de un artículo. Se compararon los resultados obtenidos mediante prueba de Chi 2 con un p≤0,05. Resultados: Ambos grupos lograron un incremento en el nivel de conocimiento sobre lesiones elementales; sin embargo, quien utilizó la aplicación móvil obtuvo resultados significativamente mejores de aprendizaje (Chi 2 p=0,014). Conclusiones: Las TIC constituyen una estrategia útil para afianzar nuevos conocimientos, se comprobó que los estudiantes que emplearon la herramienta educativa incrementaron significativamente el aprendizaje en lesiones elementales de una forma agradable y amena.

Introduction: The development and widespread access to Information and Communication Technologies (ICTs) have reinforced the view of them as didactic alternatives to improve the quality of education. These technological advances have facilitated the teaching-learning process through the use of virtual media. Knowing elementary lesions in the oral cavity tissue is important for their appropriate diagnosis and therapeutic management. Objective: To design, implement and assess the use of a mobile application in the teaching of elementary lesions of the oral cavity. Materials and methods: An intervention and experimental study that evaluated a didactic tool about oral elementary lesions, applying intervention, pre and post testing. The control group learning skills were assessed through the reading of an article. We finally compared the results via Chi2 test, with p≤0.05. Results: Although both groups showed an improvement in learning levels, the group that used the mobile application achieved significantly better results in reference to learning about elementary lesions (Chi2 p=0.014). Conclusions: ICTs have become useful strategies to strengthen new knowledge. In this study, we show that students who used the educational tool improved the learning of elementary lesions, in a significant and enjoyable way.

Patologia Bucal , Boca , Efetividade , Educação em Saúde , Tecnologia da Informação , Aprendizagem
Anticancer Res ; 40(3): 1597-1604, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32132062


Background/Aim: The incidence of oropharyngeal tumours induced by human papillomaviruses (HPV) is ever increasing. Information about oral HPV prevalence and its risk factors are very important for future screening and early diagnosis of the disease. The present study aimed to assess oral HPV prevalence in healthy population and risk factors for HPV infection, since this data is scarce or even missing in Central Europe. Patients and Methods: HPV prevalence in oral rinse and HPV-specific antibodies in peripheral blood were investigated in two groups of healthy participants. Group I consisted of 294 students who reached sexual maturity after the HPV vaccine had been licensed with mean age 23.2 years, and Group II of 215 unvaccinated participants with the mean age 55.7 years. Additionally, the risk factors were evaluated. Results: In Group I, 2% of participants were positive for oral HPV DNA. A statistically significantly higher rate (8.8%) was found in Group II. The seropositivity rates for anamnestic HPV antibodies were comparable in both groups. None of the analysed risk factors was significantly associated with oral HPV positivity. Conclusion: The lower prevalence of oral HPV DNA in younger participants suggests the positive influence of vaccination against oral HPV.

Infecções por Papillomavirus/epidemiologia , Adulto , Europa (Continente) , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Infecções por Papillomavirus/virologia , Patologia Bucal , Prevalência , Fatores de Risco , Adulto Jovem
Int J Paediatr Dent ; 30(2): 209-215, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31692163


BACKGROUND: There has been no previous report of the prevalence of paediatric oral and maxillofacial pathology in a New Zealand oral pathology diagnostic service. AIM: The aim of this study was to review cases of paediatric oral pathology to determine relative frequencies of oral lesions in this age group. DESIGN: Paediatric oral pathology cases (≤15 years of age) received between 2007 and 2016 were retrieved from the electronic database of the Oral Pathology Centre, University of Otago. Data collected included diagnoses (categorised into 12 groups), age at diagnosis, and gender. The prevalence of each diagnosis was calculated in terms of percentage of all diagnoses made. Male-to-female ratio and mean age at diagnosis were also determined. RESULTS: A total of 1139 paediatric cases were identified representing 5.2% of all cases. The most common diagnostic group was salivary gland pathology (25.4%), followed by dental (24.8%) pathology. The most prevalent lesion was mucocoele (23%), followed by dental follicle (14.1%). Malignancies were rare with only two cases identified. CONCLUSION: The findings provide an insight into the prevalence of paediatric oral pathology for clinicians. Mucocoele was the most common diagnosis made, suggesting a high prevalence of soft tissue injury as a main presenting concern warranting diagnosis and management through biopsy.

Doenças da Boca , Patologia Bucal , Adolescente , Biópsia , Criança , Feminino , Humanos , Masculino , Nova Zelândia , Estudos Retrospectivos
J Investig Clin Dent ; 10(4): e12432, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31566919


AIMS: The aim of the present study was to determine the range, frequency, prevalence, and distribution of oral lesions submitted for histopathological diagnosis at the oral pathology laboratory at Kuwait University. METHODS: A retrospective analysis was conducted of all cases submitted to the oral pathology laboratory over an 18-year period. Age, sex, histopathological diagnosis, and location of the lesions were recorded. Lesions were classified into 10 diagnostic categories. RESULTS: Of the 697 biopsies examined, the average age of the patients ranged from 1 to 93 years with a mean age of 37.83 ± 16.62 (mean ± SD). The most common diagnostic category was mucosal pathologies (N = 205, 29.4%), followed by odontogenic cysts (N = 158, 22.7%) and reactive lesions (N = 97, 13.9%). The three most common histopathological diagnoses were hyperkeratosis (N = 70), dentigerous cyst (N = 48), and mucocele (N = 44). Twenty-five malignant neoplasms were diagnosed, the majority of them in males. A significant association was observed between age and the group of lesions of the oral cavity (P ≤ 0.001). CONCLUSIONS: The present study provides the first set of data from Kuwait that covers a wide range of oral lesions. Mucosal pathologies were the most frequently diagnosed lesions and the majority of diagnoses were benign.

Doenças da Boca , Patologia Bucal , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Biópsia , Criança , Pré-Escolar , Humanos , Lactente , Kuweit , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Universidades , Adulto Jovem
Oral Maxillofac Surg Clin North Am ; 31(4): 569-578, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31427192


Benign cysts and neoplasms of the maxillofacial region can vary in behavior, with some growing rapidly and resulting in destruction of surrounding structures. Despite their benign histology, many require often-morbid treatment to prevent recurrence of these lesions. Several less invasive and adjunctive medical treatments have been developed to lessen the morbidity of surgical treatment. As the molecular and genomic pathogenesis of these lesions is better understood, more directed treatments may lessen the burden for patients.

Ameloblastoma/cirurgia , Neoplasias Maxilomandibulares/cirurgia , Cistos Odontogênicos/cirurgia , Ameloblastoma/patologia , Humanos , Neoplasias Maxilomandibulares/patologia , Recidiva Local de Neoplasia , Cistos Odontogênicos/patologia , Patologia Bucal
J Oral Pathol Med ; 48(7): 509, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31183896
Poblac. salud mesoam ; 16(2): 134-154, Jan.-Jun. 2019. tab
Artigo em Espanhol | LILACS | ID: biblio-1091667


RESUMEN Objetivo: determinar la frecuencia de las diferentes lesiones de la mucosa oral en el internado clínico de la Facultad de Odontología de la Universidad de Costa Rica (UCR). Metodología: estudio retrospectivo de 263 informes de lesiones orales recuperados del archivo de biopsias de la Facultad de Odontología de la UCR del 2008 a 2015. Se evaluaron y analizaron de forma descriptiva y cualitativa información sobre el sexo, edad, localización de la lesión y diagnóstico histopatológico. Resultados: los casos de lesiones de la mucosa oral afectaron preferentemente a las mujeres (n= 144; 54.8 %), el promedio de edad fue 48.8 años (16.4 DS) y con lesiones predominantemente localizadas en lengua (n= 68; 25.9 %), encía (n=62; 23.6 %) y labio (n=61; 23.2 %). Las lesiones proliferativas no neoplásicas (n=101; 38.7 %), lesiones potencialmente malignas (n=29; 11.1 %) y lesiones epiteliales benignas y malignas (n=24; 9.1 %) fueron los grupos más prevalentes. Las cuatro lesiones más predominantes fueron la hiperplasia fibrosa, hiperplasia fibrosa inflamatoria, liquen plano e hiperqueratosis sin atipia. Conclusiones: las lesiones proliferativas no neoplásicas fueron las predominantes, siendo en forma individual la hiperplasia fibrosa la lesión más prevalente. Estos resultados pueden ser útiles para comprender la distribución de las enfermedades bucales en una muestra nacional.

ABSTRACT Objective: to determine the frequency of the different lesions of the oral mucosa in the clinical internship of the Faculty of Dentistry of the University of Costa Rica (UCR). Methodology: retrospective study of 263 reports of oral lesions recovered from the biopsies file of the Faculty of Dentistry of the UCR from 2008 to 2015. Information on sex, age, location of the lesion and histopathological diagnosis was collected and evaluated in a descriptive and qualitative manner. Results: cases of oral mucosal lesions affected women preferentially (n = 144, 54.8 %), the average age was 48.8 years (16.4 SD) and with lesions predominantly located in tongue (n = 68, 25.9%), gum (n = 62, 23.6 %) and lip (n = 61, 23.2 %). Non-neoplastic proliferative lesions (n ​​= 101, 38.7 %), potentially malignant lesions (n ​​= 29, 11.1%) and benign and malignant epithelial lesions (n ​​= 24, 9.1 %) were the most prevalent groups. The four most predominant lesions were fibrous hyperplasia, inflammatory fibrous hyperplasia, lichen planus and hyperkeratosis without atypia. Conclusions: non-neoplastic proliferative lesions were predominant, with the fibrous hyperplasia being the most prevalent lesion. These results may be useful to understand the distribution of oral diseases in a national sample.

Humanos , Patologia Bucal , Costa Rica , Doenças da Boca/epidemiologia , Mucosa Bucal
J Am Dent Assoc ; 150(6): 531-539, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31030934


BACKGROUND: Dentists play an important role in the detection and diagnosis of oral diseases, including oral cancer and its precursor lesions. There are few comprehensive reviews in the recent literature that examine the scope and trends of oral disease diagnoses by dentists. METHODS: The authors analyzed all accessions to the Toronto Oral Pathology Service at the Faculty of Dentistry at the University of Toronto in Toronto, Ontario, Canada, from 2005 through 2015 using a custom-built database. They used these data to calculate the temporal trends in the diagnoses of oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). RESULTS: A total of 63,483 biopsy specimens were submitted primarily by dentists from 2005 through 2015. From these, 2,679 cases of OED and 828 OSCC were diagnosed. The authors' results show a 3.8-fold increase in the number of epithelial dysplasias and a 1.8-fold increase in mucosal carcinomas over the study period. The rate of increase of OED and OSCC was significantly higher than the rate of increase of total oral carcinomas diagnosed in the region, the population changes, and the number of dentists in the region. CONCLUSIONS AND PRACTICAL IMPLICATIONS: Within the limitations of a study of a single large oral pathology biopsy service, the analysis of diagnoses shows that dentists are increasingly involved in the detection of oral mucosal carcinoma and precursor lesions. The dental community plays an important and increasing role in the detection of oral cancer and potentially malignant disorders. Increased awareness among oral health care and nonoral health care professionals may increase early detection of OSCC.

Carcinoma de Células Escamosas , Neoplasias Bucais , Canadá , Odontólogos , Humanos , Patologia Bucal
Peptides ; 116: 8-15, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31004688


Oral and maxillofacial skeletal muscles are critical for oral motor functions, and severe damage to these muscles by trauma or surgery may lead to persistent functional impairment. This study investigated the effects of SVVYGLR (SV) peptide, a thrombin-cleaved osteopontin-derived motif, on histopathological wound healing and functional repair after severe injury of skeletal muscles. A rat model of volumetric muscle loss bilateral masseter muscle was developed. A single dose of SV-peptide or phosphate-buffered saline (PBS) was separately injected into the injured muscle belly. Histopathological and functional analyses were performed 1-8 weeks after the treatment. Behavioral analysis during free-feeding revealed that the feeding rate markedly increased in the SV-peptide group, in contrast, the PBS group showed fewer changes after the injury. Electromyogram recordings from injured muscles demonstrated amplification of rectified burst activity over time accompanied by increased maximal amplitude and duration in the SV-peptide group, in contrast, the PBS group showed moderate changes. A lissajous figure for bilateral masseter muscle activities also revealed superior functional recovery by the SV-peptide treatment. The SV-peptide also facilitated regeneration of muscles composed of matured myofibers with a greater diameter compared to the PBS group. In addition, granulation in the earlier period and fibrosis in the later period of wound healing were significantly inhibited by the SV-peptide treatment but not by the PBS treatment. Therefore, local application of the SV-peptide could help facilitate regeneration of muscles, inhibition of fibrosis, and improvement of functional impairment of oral and maxillofacial skeletal muscles damaged by severe trauma or surgery.

Traumatismos Maxilofaciais/terapia , Oligopeptídeos/genética , Osteopontina/genética , Regeneração/efeitos dos fármacos , Animais , Diferenciação Celular/efeitos dos fármacos , Eletromiografia , Humanos , Traumatismos Maxilofaciais/genética , Músculo Esquelético/diagnóstico por imagem , Músculo Esquelético/efeitos dos fármacos , Músculo Esquelético/crescimento & desenvolvimento , Miocárdio/metabolismo , Miocárdio/patologia , Osteopontina/química , Patologia Bucal , Ratos , Regeneração/genética
J Investig Clin Dent ; 10(3): e12410, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30916486


AIM: The epidemiological features and distribution of pediatric oral and maxillofacial pathology in South Australia, Australia, is unknown. The medical and dental specialties involved in the management of oral and maxillofacial pathology is also unknown. The aim of the present study was to audit oral and maxillofacial pathology specimens submitted for diagnosis in a pediatric tertiary-referral hospital setting. METHODS: Histopathology records were retrieved from the Women's and Children's Hospital, Adelaide over a 16-year period. Age, sex, histopathological diagnosis, location of the lesion, and department involved were recorded. Lesions were classified into 12 categories. RESULTS: A total of 676 lesions involving the oral and maxillofacial region were collected from patients aged 0-18 years. The mean age was 8.71 years. Diagnosis was not significantly associated with sex (P = 0.123). A total of 97.37% of cases were benign, with connective tissue and salivary gland lesions most frequently biopsied and more frequently biopsied by medical departments. Mucoceles (19.23%) were most commonly diagnosed, followed by dentigerous cysts (5.62%). The Department of Paediatric Dentistry submitted most specimens, followed by the Department of Otolaryngology, the Australian Craniofacial Unit, and the Departments of Paediatric Surgery and Plastics. CONCLUSION: The present study provides valuable understanding into the epidemiological features of, and the specialties involved in, oral and maxillofacial histopathology in an Australian pediatric population.

Doenças da Boca , Patologia Bucal , Adolescente , Austrália , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Estudos Retrospectivos , Austrália do Sul
Dentomaxillofac Radiol ; 48(4): 20180075, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30707623


OBJECTIVES: To evaluate thermal images (TIs) by using an algorithm for optimized region of interest (ROI) and image segmentation, in order to find zones of the facial skin surface with asymmetrical temperature, and to test consistency with CT findings, to detect maxillofacial pathologies (i.e. tumours). METHODS: The following steps for the TI evaluation were applied: data acquisition/pre-processing of frontal face and mouth projection, detection of face and mouth external contour, finding face and mouth symmetry axis, calculation of differences in average and maximal temperatures between left and right face and mouth sides, image segmentation of the selected ROI, and evaluation of diagnostic accuracy by comparing the TI results with CT findings. RESULTS: In healthy subjects, the average temperature difference between left/right sides of facial and mouth ROI was negligible (0.02 ± 0.21 °C and 0.05 ± 0.19 °C, respectively; n = 23). In the presence of tumour, the average temperature difference was higher in corresponding TIs (0.47 ± 0.1 °C and 0.66 ± 0.1 °C, for facial and mouth ROI, respectively; n = 19, p < 0.05). For large tumours, thermal asymmetry in the corresponding TI is easily detected, and image segmentation is optional for finding the affected zone. For small or deeply localized tumours, segmentation of the mouth cavity of the ROI was required for the detection of hot and cold spots. CONCLUSIONS: Asymmetrical temperature zones and their location as detected from thermal images coincide well with the presence and localization of maxillofacial pathologies (i.e. tumours) established by CT. However, accurate information could often be obtained only after application of image segmentation algorithm to the selected ROI.

Neoplasias Bucais , Patologia Bucal , Tomografia Computadorizada por Raios X , Algoritmos , Humanos , Processamento de Imagem Assistida por Computador , Neoplasias Bucais/diagnóstico por imagem
Artigo em Inglês | MEDLINE | ID: mdl-30448231


OBJECTIVES: Odontogenic tumors (ODTs) are a heterogeneous group of lesions derived from elements of tooth-forming tissues. No detailed data on the incidence of odontogenic tumors in the United Kingdom have been published. The aim of this study was to retrospectively describe the range and incidence of odontogenic tumors from 1992 to 2016 in a single specialist unit and to compare this population with others. STUDY DESIGN: By using the Oral and Maxillofacial Pathology database, Sheffield (UK), we included both local and referred consultation cases. A proportion of diagnoses were reclassified in accordance with the 2017 World Health Organization classification. RESULTS: In total, 559 odontogenic tumors were diagnosed. Overall, the most common lesions were ameloblastoma (196 [33.8%]), odontoma (148 [25.5%]), and odontogenic myxoma (37 [6.3%]), but this varied between local and referral case populations, with odontomas being most common in the local population (43%). The sites affected and the gender and age of patients were similar to other Western populations. Malignant ODTs comprised 33 cases (5.7%), of which 9 (27.3%) were ameloblastic carcinoma. The majority of the malignant ODTs comprised referral cases. CONCLUSIONS: Here, we present the first detailed data on ODTs within a UK population, and the pattern of incidence from the local population is similar to other Western populations. The exceptional rarity of malignant ODTs emphasizes the need for specialist centers for their treatment to gain diagnostic experience.

Ameloblastoma , Tumores Odontogênicos , Odontoma , Ameloblastoma/diagnóstico , Ameloblastoma/epidemiologia , Ameloblastoma/terapia , Humanos , Tumores Odontogênicos/diagnóstico , Tumores Odontogênicos/epidemiologia , Tumores Odontogênicos/terapia , Odontoma/diagnóstico , Odontoma/epidemiologia , Odontoma/terapia , Patologia Bucal , Estudos Retrospectivos , Reino Unido/epidemiologia
Oral Dis ; 25(1): 142-149, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30099823


OBJECTIVES: Accurate diagnosis of salivary gland neoplasms (SGN) in many centers in Africa is limited by poor diagnostic resources and ancillary services. Hence, we have carried out a multicenter epidemiological study to understand the true burden of SGN in Nigeria. METHOD: In this descriptive cross-sectional study, we have deployed resources available to members of the African Oral Pathology Consortium (AOPRC) to examine the burden of salivary gland lesions in Nigeria, using a multicenter approach. Data from seven major tertiary health institutions in northern, western, and southern Nigeria were generated using a standardized data extraction format and analyzed using the Epi-info software (Version 7.0, Atlanta, USA). RESULT: Of the 497 cases examined across the seven centers, we observed that SGN occurred more in females than males. Overall, pleomorphic salivary adenoma (PA) was found to be the most common. PA was found to be the commonest benign SGN while adenocystic carcinoma (ADCC) was the commonest malignant SGN. Regional variations were observed for age group, diagnosis, and gender distribution. Significant statistical differences were found between males and females for malignant SGNs (p-value=0.037). CONCLUSION: We found regional variation in the pattern of distribution of SGN in Nigeria. This is the largest multicenter study of SGN in Nigeria, and our findings are robust and representative of the epidemiology of this neoplasm in Nigeria.

Neoplasias das Glândulas Salivares/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Criança , Estudos Transversais , Feminino , Geografia , Humanos , Masculino , Pessoa de Meia-Idade , Nigéria/epidemiologia , Patologia Bucal , Estudos Retrospectivos , Centros de Atenção Terciária , Adulto Jovem
Ir Med J ; 112(10): 1017, 2019 12 16.
Artigo em Inglês | MEDLINE | ID: mdl-32081194


Aim: To undertake a retrospective analysis of the use of a diagnostic pathology service, to determine the source of oral biopsies submitted for histological analysis, and to examine the range and frequencies of histologically diagnosed oral lesions in an Irish population. Methods: A retrospective analysis was carried out on all oral biopsies submitted for histological analysis to an oral and maxillofacial diagnostic pathology service from June to December 2015. Results: In total 724 oral biopsies were submitted. The majority of diagnoses were benign (80.3%) and the remaining diagnoses were made up of malignancies (6.7%) and potentially malignant disorders (PMDs), histologically characterised by epithelial dysplasia (13%). Less than 1% of biopsies were submitted from general dentists in primary care. Conclusion: This study showed that oral biopsies are not submitted from the primary care setting, but rather from hospital-based specialist units or referral-based specialist practitioners. There was a broad range of histological diagnoses, the majority of which were benign.

Odontologia Geral/estatística & dados numéricos , Doenças da Boca/diagnóstico , Patologia Bucal/estatística & dados numéricos , Padrões de Prática Odontológica/estatística & dados numéricos , Biópsia/estatística & dados numéricos , Unidade Hospitalar de Odontologia/estatística & dados numéricos , Feminino , Humanos , Masculino , Neoplasias Bucais/diagnóstico , Encaminhamento e Consulta/estatística & dados numéricos , Estudos Retrospectivos
Rev. salud pública (Córdoba) ; 23(2): 107-109, 2019.
Artigo em Inglês, Espanhol | LILACS | ID: biblio-1049391


El labio leporino con o sin paladar hendido se encuentra entre los principales defectos congénitos y afecta aproximadamente 1:700 de los recién nacidos vivos (1). Se considera que la etiología de esta patología es multifactorial, incluyendo una interacción entre factores genéticos y ambientales (2,3)

Cleft lip and/or palate (CL/P) are among the most prevalent of all birth defects in human, affecting approximately 1:700 live births(1). The etiology of CL/P is thought to be multifactorial, involving an interaction between genetic and environmental factors (2,3).

A fissura labial e / ou palatina (FL / P) está entre as mais prevalentes de todos os defeitos congênitos em humanos, afetando aproximadamente 1: 700 nascidos vivos (1). A etiologia da CL / P é considerada multifatorial, envolvendo uma interação entre fatores genéticos e ambientais (2,3)

Fenda Labial/psicologia , Patologia Bucal , Adaptação Psicológica , Causalidade , Fissura Palatina/psicologia , Ajustamento Emocional
Acta odontol. Colomb. (En linea) ; 9(2): 112-122, 2019. ilus, Tab
Artigo em Espanhol | LILACS, COLNAL | ID: biblio-1026412


El presente informe tiene como propósito reportar un caso clínico de odontoma complejo intraóseo ubicado en la zona posterior del tercer molar inferior derecho, molar que se encuentra retenido y que es parte principal de la estructura del odontoma. Un odontoma ­o hamartoma de tejido odontogénico­ es una alteración del desarrollo o malformación que presenta tejidos dentales como esmalte, dentina, cemento y pulpa. La Organización Mundial de la Salud (OMS) define los odontomas como tumores odontogénicos benignos mixtos, epiteliales y mesenquimáticos; son, por lo general, asintomáticos; su etiología no se encuentra definida ­por lo que se asocian a distintos factores­; se clasifican en compuestos y complejos ­en virtud de diferencias en la organización del tejido dentario­; y, regularmente, son diagnosticados mediante análisis radiográficos y con biopsias enviadas a patología. Al Paciente ­de sexo masculino, 45 años, hipertenso controlado­ se le realizaron radiografías panorámica y tomografía. Una vez analizados los estudios complementarios, se realizó la enucleación y la exodoncia quirúrgica los molares tercero y segundo, que resultaron afectados. Adicionalmente, se utilizó Plasma Rico en Fibrina (PRF) para rellenar la cavidad ósea. Finalmente, se realizó estudio histopatológico, donde se confirmó el diagnóstico de odontoma.

Purpose: to report a clinical case of Odontoma complex intraosseous, located in the posterior area of the lower right third molar, which is retained, the same that is forming a main part of the structure of the odontoma. The odontomas are a developmental alteration or malformation known as hamartoma of odontogenic tissue, presents dental tissues such as enamel, dentin, cement and pulp, the World Health Organization defines it as benign mixed odontogenic tumors, epithelial and mesenchymal; are classified into compounds and complexes, its difference is the organization of dental tissue, usually are asymptomatic, its etiology is not defined by what is associated with various factors, by virtue of differences in the organization of dental tissue, regularly they are diagnosed by radiographic analysis and with protests sent to pathology. The patient ­male, 45 years old, controlled hypertensive­ had panoramic radiographs and tomography. Once the complementary studies were analyzed, enucleation and surgical exodontist were performed on the third and second molars, which were affected. In addition, Plasma Rich in Fibrin (PRF) was added to fill the bone cavity. Finally, a histopathological study was performed, where the diagnosis of odontoma was confirmed.

Humanos , Odontoma , Patologia Bucal , Tomografia , Diagnóstico , Equador , Dente Serotino , Neoplasias
Shanghai Kou Qiang Yi Xue ; 28(5): 557-560, 2019 Oct.
Artigo em Chinês | MEDLINE | ID: mdl-32274493


PURPOSE: To construct clinical practice system, making up for the shortcomings in the instructional framework of oral histology and pathology, promoting the integration of theory and clinical practice, and enhancing teaching quality of long-term students of stomatology. METHODS: Laying down clinical practice plans and formulating technical operation criteria for pathological experiments, constructing a complete database and training high-level teachers, and evaluating through the following three aspects: practice assessment, teacher-student symposium and questionnaire survey. RESULTS: After completing the clinical practice, the students got the average score of 89.37. In questionnaire survey, the students generally expressed that they had a better understanding of the specialized characteristics and routine skills of the speciality, and improved their practical ability, thus stimulating their interest in self-directed learning. CONCLUSIONS: The construction and practice of clinical practice system of oral histology and pathology can effectively improve the educational objectives and teaching quality of this discipline, which will play a positive role in scientific research and future medical work of long-term students majoring in stomatology.

Medicina Bucal , Estudantes de Medicina , Humanos , Aprendizagem , Patologia Bucal , Estudantes , Inquéritos e Questionários , Ensino
Belo Horizonte; s.n; 2019. 42 p. ilus, tab.
Tese em Inglês, Português | BBO - Odontologia | ID: biblio-1016466


Este estudo investigou a frequência do cisto odontogênico calcificante (COC) submetido à análise histopatológica em diferentes regiões geográficas do Brasil. Em uma análise retrospectiva (1953-2016), arquivos de biópsias de 10 centros de Patologia Oral e Maxilofacial localizados em diferentes estados do Brasil: Goiás, Minas Gerais, Pará, Rio de Janeiro, Rio Grande do Norte, Rio Grande do Sul, Santa Catarina e São Paulo foram analisados. Dados demográficos, características clinicopatológicas, aspectos radiográficos e tipos de biópsia foram avaliados descritivamente. O teste Mann-Whitney foi utilizado para determinar a associação entre sintomas, tempo de evolução e tamanho da lesão. A significância estatística foi estabelecida como p<0,05. O diagnóstico do COC foi de acordo com a classificação da Organização Mundial de Saúde (2017). Adicionalmente, uma revisão da literatura de série de casos de COC foi realizada em quatro bases de dados eletrônicas (PubMed, Medline Ovid, Web of Science e Scopus). Dos 198.350 espécimes de biopsias exploradas, 268 casos de COC foram avaliados, representando 0,1% das lesões orais dos centros estudados. Em geral, indivíduos do sexo feminino (n=142, 54.0%), na segunda década de vida (n=76, 31.0%) com acometimento da maxila (n=141, 54.4%) foram os mais afetados. O tamanho médio das lesões dos indivíduos sintomáticos foi maior que o dos casos assintomáticos (p=0,026). A revisão da literatura apresentou maior frequência dos casos de COC na Ásia (186 casos) e na Europa (68 casos), acometendo principalmente os homens (n=247, 56.2%) na terceira década de vida. O COC é uma lesão rara. Novos dados sobre as características clinicopatológicas de 268 casos foram adicionados à literatura. Os dados referentes ao gênero e idade dos pacientes brasileiros aqui relatados são diferentes dos achados de séries de casos relatados já na literatura. Este estudo fornece informações que podem ajudar os clínicos, patologistas e cirurgiões no diagnóstico e manejo do COC.

This study investigated the frequency of calcifying odontogenic cyst (COC) submitted to histopathological analysis in different geographic regions of Brazil. In a retrospective analysis (1953-2016), biopsy files of 10 Oral and Maxillofacial Pathology centers located in different states of Brazil: Goiás, Minas Gerais, Pará, Rio de Janeiro, Rio Grande do Norte, Rio Grande do Sul, Santa Catarina and São Paulo were analyzed. Demographic data, clinicopathological characteristics, radiographic aspects and treatment were evaluated descriptively. The Mann-Whitney test was used to determine the association between symptoms, evolution time and lesion size. Statistical significance was set as p<0.05. The diagnosis of COC was according to the classification of the World Health Organization (2017). In addition, a literature review of case series was carried out in four electronic databases (PubMed, Medline Ovid, Web of Science and Scopus). Of 198,350 specimens of biopsies analyzed, 268 cases of COC were surveyed, representing 0.1% of the oral lesions at the centers studied. Overall, female patients (n=142, 54.0%) in their second decade of life (n=76, 31.0%) and the maxilla (n=141, 54.4%) were more affected. The mean lesion size of symptomatic individuals was larger than that of cases without symptoms (p=0.026). The literature review showed a higher frequency in Asia (186 cases) and Europe (68 cases), mainly affecting men (n=247, 56.2%) in the third decade of life. COC is a rare lesion. Additional data on the clinicopathological features of 268 cases have been added to the literature. Data regarding gender and age of the Brazilian patients reported herein are different with findings of case series and retrospective studies reported in the literature. This study provides information that could help clinicians, pathologists, and surgeons in the diagnosis and management of COC.

Ferimentos e Lesões , Cistos Odontogênicos/epidemiologia , Tumores Odontogênicos , Cisto Odontogênico Calcificante/epidemiologia , Diagnóstico , Arcada Osseodentária , Patologia Bucal , Relatos de Casos , Estudo Multicêntrico