Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 878
Filtrar
1.
Rev Assoc Med Bras (1992) ; 66(7): 1002-1008, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32844928

RESUMO

The increase in bilirubin levels in newborns can cause toxic effects on the auditory system, which can lead to hearing loss. This review aimed to verify the impact of hyperbilirubinemia in the hearing of newborns, relating audiological findings to serum levels of bilirubin. A literature review was conducted during October 2017, using the terms "hyperbilirubinemia", "jaundice", "infant", "newborn" and "hearing loss", on databases CAPES journals, MEDLINE and BIREME (SciELO, BBO). 827 studies were identified and 59 were selected for full-text reading, resulting in the selection of seven articles that met the inclusion criteria and were considered relevant to the sample of this study. All the reviewed studies performed brainstem auditory evoked potential as the main test for audiological evaluation. Changes in the audiological findings of neonates with hyperbilirubinemia were observed in all studies. There was no consensus on the serum bilirubin levels that may cause auditory changes; however, the relationship between hearing disorders and blood levels of bilirubin was positive. We identify the need to establish reference values for bilirubin levels considered critical for the occurrence of hearing disorders as well as the audiological follow-up of neonates with hyperbilirubinemia.


Assuntos
Perda Auditiva , Hiperbilirrubinemia , Audiometria , Bilirrubina , Potenciais Evocados Auditivos do Tronco Encefálico , Perda Auditiva/complicações , Humanos , Hiperbilirrubinemia/complicações , Recém-Nascido
3.
PLoS One ; 15(8): e0237152, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32745118

RESUMO

The population of older adults that have Dual Sensory Loss (DSL) is increasing, yet most research to date has focused on single sensory impairment and is inconclusive as to whether DSL is associated with worse impact on health and well-being over single sensory loss. The primary aim of this study was to characterize the health and functioning of community-dwelling older adults with DSL who were receiving sensory rehabilitation, using an understudied assessment: the interRAI Community Health Assessment (CHA). The secondary aim was to investigate whether older adults with DSL had worse health-related outcomes than their peers with only vision loss (VL) or only hearing loss (HL). We report and compare the interRAI CHA results in a sample of 200 older adults (61+ years of age) who had DSL, VL or HL. Overall, all sensory impairment groups showed high functioning in the areas of cognition, communication, activities of daily living, depression, and psycho-social well-being. DSL was not always associated with worse outcomes compared to a single sensory loss. Rather, the results varied depending on the tasks assessed, as well as which groups were compared. Our findings highlight that despite the negative impact of sensory losses, community-dwelling older adults receiving sensory rehabilitation services tend to have overall good health and a high level of independence. These results also show that DSL is not always associated with worse outcomes compared to a single sensory loss. Further research is needed to better characterize older adults with DSL who have more severe sensory and cognitive difficulties than those in our sample, and among those who are not receiving rehabilitation services.


Assuntos
Atividades Cotidianas , Cegueira/reabilitação , Perda Auditiva/reabilitação , Qualidade de Vida , Idoso , Idoso de 80 Anos ou mais , Cegueira/complicações , Cegueira/fisiopatologia , Cognição , Comunicação , Feminino , Perda Auditiva/complicações , Perda Auditiva/fisiopatologia , Humanos , Vida Independente , Masculino , Pessoa de Meia-Idade , Reabilitação Neurológica/métodos
4.
PLoS One ; 15(6): e0231563, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32589635

RESUMO

BACKGROUND: The aim of this study was to assess the association between anxiety and depression with physical and sensory functional difficulties, among adults living in five low and middle-income countries (LMICs). METHODS AND FINDINGS: A secondary data analysis was undertaken using population-based disability survey data from five LMICs, including two national surveys (Guatemala, Maldives) and 3 regional/district surveys (Nepal, India, Cameroon). 19,337 participants were sampled in total (range 1,617-7,604 in individual studies). Anxiety, depression, and physical and sensory functional difficulties were assessed using the Washington Group Extended Question Set on Functioning. Age-sex adjusted logistic regression analyses were undertaken to assess the association of anxiety and depression with hearing, visual or mobility functional difficulties. The findings demonstrated an increased adjusted odds of severe depression and severe anxiety among adults with mobility, hearing and visual functional difficulties in all settings (with ORs ranging from 2.0 to 14.2) except for in relation to hearing loss in India, the Maldives and Cameroon, where no clear association was found. For all settings and types of functional difficulties, there was a stronger association with severe anxiety and depression than with moderate. Both India and Cameroon had higher reported prevalences of physical and sensory functional difficulties compared with Nepal and Guatemala, and weaker associations with anxiety and depression. CONCLUSION: People with physical and sensory functional difficulties are more likely to report experiencing depression and anxiety. This evidence supports the need for ensuring a good awareness of mental health among those working with individuals with physical and sensory functional difficulties in LMICs. This implies that these practitioners must have the skills to identify anxiety and depression. Furthermore, mental health services must be available and accessible to patients with these conditions, which will likely require further programmatic scale-up in these LMIC settings.


Assuntos
Ansiedade/patologia , Depressão/patologia , Perda Auditiva/patologia , Transtornos da Visão/patologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Ansiedade/complicações , Ansiedade/epidemiologia , Depressão/complicações , Depressão/epidemiologia , Países em Desenvolvimento , Feminino , Perda Auditiva/complicações , Perda Auditiva/epidemiologia , Humanos , Índia/epidemiologia , Modelos Logísticos , Masculino , Saúde Mental , Pessoa de Meia-Idade , Prevalência , Índice de Gravidade de Doença , Inquéritos e Questionários , Transtornos da Visão/complicações , Transtornos da Visão/epidemiologia , Adulto Jovem
5.
Gerontology ; 66(4): 351-361, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32512565

RESUMO

BACKGROUND: Vision loss and hearing loss are common in later life and are associated with cognitive impairment and neuropsychiatric symptoms. There is a need to better understand how individual characteristics, such as poor sensory functioning, are linked with familial well-being. OBJECTIVES: The aim of this study was to investigate whether, among persons with neuropsychiatric symptoms, age-related sensory loss is related to increased emotional distress reported by their family and friends. METHODS: The sample comprised 537 participant-informant dyads from the Personality and Total Health through Life (PATH) study, a community-based cohort. Participants were aged between 72 and 79 years (56% men), and all were reported to exhibit at least 1 neuropsychiatric symptom. Informants were participants' spouse (50%), child (35%), friend (7%), or other relatives (7%). Neuropsychiatric symptom-related distress of friends and family was assessed with the distress subscale of the Neuropsychiatric Inventory (NPI). Sensory functioning in participants was assessed by visual acuity and self-reported hearing difficulties. Ordinal logistic regression analyses estimated the association between sensory problems and NPI distress. RESULTS: In models adjusted for informant dyadic relationship and socio-demographics, both lower visual acuity (B = 0.23, SE = 0.10) and self-reported hearing difficulty (B = 0.15, SE = 0.06) were associated with increased levels of distress. The increased informant distress associated with poor visual acuity was attenuated after adjusting for neurocognitive disorder and health conditions (p = 0.069). A significant interaction between vision and hearing remained after multivariable adjustment (χ2(1) = 6.73, p = 0.010). CONCLUSIONS: Friends and family of persons with poor visual acuity and perceived hearing difficulties report elevated levels of neuropsychiatric symptom-related distress relative to friends and family of persons with poor sensory functioning in only 1 sensory domain or unimpaired levels of vision and hearing. These findings provide evidence of the third-party effects of sensory loss in the context of neuropsychiatric symptoms, and in particular show how dual sensory loss can confer additional challenges over and above the effects of a single sensory loss.


Assuntos
Disfunção Cognitiva/complicações , Família/psicologia , Amigos/psicologia , Perda Auditiva/complicações , Transtornos da Visão/complicações , Idoso , Austrália , Estudos de Coortes , Feminino , Humanos , Vida Independente , Masculino , Testes Neuropsicológicos , Angústia Psicológica , Autorrelato , Acuidade Visual
6.
PLoS One ; 15(5): e0232947, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32469959

RESUMO

OBJECTIVE: To compare relative efficacy of different antibiotic therapies either with or without the addition of corticosteroids among adult patients with acute bacterial meningitis on all-cause mortality, neurological complications and any hearing loss. METHODS: We searched nine databases from inception to 8 February 2018 for randomized controlled trials evaluating pharmacological interventions and clinical outcomes in adult bacterial meningitis. An updated search from 9 February to 9 March 2020 was performed, and no new studies met the inclusion criteria. Study quality was assessed using the revised Cochrane Risk of Bias Tool. The Grading of Recommendations Assessment, Development and Evaluation system was used for quality of evidences evaluation. Meta-analyses were conducted to estimate the risk ratio with 95% confidence interval for both direct and indirect comparisons on the primary outcomes of all-cause mortality, neurologic sequelae and any hearing loss. The study was registered in PROSPERO (CRD42018108062). RESULTS: Nine RCTs were included in systematic review, involving 1,002 participants with a mean age ranging between 25.3 to 50.56 years. Six RCTs were finally included in the network-meta analysis. No significant difference between treatment was noted in meta-analysis. Network meta-analysis suggests that corticosteroids in combination with antibiotic therapy was more effective in reducing the risk of any hearing loss compared to mono antibiotic therapy (RR 0.64; 95%CI, 0.45 to 0.91, 4 RCTs, moderate certainty of evidence). Numerical lower risk of mortality and neurological complications was also shown for adjunctive corticosteroids in combination with antibiotic therapy versus mono antibiotic therapy (RR 0.65; 95%CI, 0.42 to 1.02, 6 RCTs, moderate certainty of evidence; RR 0.75; 95%CI, 0.47 to 1.18, 6 RCTs, moderate certainty of evidence). No differences were noted in the adverse events between different therapies. The overall certainty of evidence was moderate to very low for all primary outcomes examined. CONCLUSIONS: Results of this study suggest that corticosteroids therapy in combination with antibiotic is more effective than mono antibiotic therapy in reducing the risk of any hearing loss in adult patients with acute bacterial meningitis. More well-design RCTs to investigate relative effective treatments in acute bacterial meningitis particularly in adult population should be mandated to aid clinicians in treatment recommendations.


Assuntos
Corticosteroides/uso terapêutico , Antibacterianos/uso terapêutico , Meningites Bacterianas/tratamento farmacológico , Adulto , Idoso , Quimioterapia Combinada/métodos , Feminino , Perda Auditiva/complicações , Humanos , Masculino , Pessoa de Meia-Idade , Metanálise em Rede , Resultado do Tratamento
7.
Otolaryngol Head Neck Surg ; 163(1): 91-93, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32366178

RESUMO

COVID-19 is a rapidly growing global pandemic caused by a novel coronavirus. With no vaccine or definitive treatment, public health authorities have recommended a strategy of "social distancing," reducing individual interaction, canceling elective procedures, and limiting nonessential services. Health care providers must determine what procedures are considered "elective," balancing risk of treatment delays with that of coronavirus exposure to patient, family, and providers. Given critical periods for language development and the long-term impact of auditory deprivation, some audiologic and otologic services should be considered essential. In this article, we describe the experience of a quaternary referral pediatric hospital in Seattle, the epicenter of COVID-19 in the United States, and share strategies for risk minimization employed by Seattle Children's Hospital. We hope that this work can be a reference for other centers continuing care for children who are deaf and hard of hearing during the COVID-19 and future resource-limiting crises.


Assuntos
Betacoronavirus , Infecções por Coronavirus/complicações , Surdez/terapia , Transmissão de Doença Infecciosa/prevenção & controle , Perda Auditiva/terapia , Otolaringologia/métodos , Pandemias , Pneumonia Viral/complicações , Criança , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/transmissão , Surdez/complicações , Perda Auditiva/complicações , Humanos , Pneumonia Viral/epidemiologia , Pneumonia Viral/transmissão , Saúde Pública
8.
J Laryngol Otol ; 134(5): 387-397, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32468973

RESUMO

BACKGROUND: Hearing loss affects over 1.3 billion individuals worldwide, with the greatest burden among adults. Little is known regarding the association between adult-onset hearing loss and employment. METHODS: Seven databases (PubMed, Embase, Cochrane Library, ABI/Inform Collection, Business Source Ultimate, Web of Science and Scopus) were searched through to October 2018. The key word terms used related to hearing loss and employment, excluding paediatric or congenital hearing loss and deaf or culturally deaf populations. RESULTS: The initial search resulted in 13 144 articles. A total of 7494 articles underwent title and abstract screening, and 243 underwent full-text review. Twenty-five articles met the inclusion criteria. Studies were set in 10 predominantly high-income countries. Seven of the 25 studies analysed regionally or nationally representative datasets and controlled for key variables. Six of these seven studies reported associations between hearing loss and employment. CONCLUSION: The highest quality studies currently available indicate that adult-onset hearing loss is associated with unemployment. However, considerable heterogeneity exists, and more rigorous studies that include low- and middle-income countries are needed.


Assuntos
Efeitos Psicossociais da Doença , Emprego/estatística & dados numéricos , Perda Auditiva/complicações , Adulto , Idoso , Idoso de 80 Anos ou mais , Emprego/economia , Perda Auditiva/economia , Humanos , Pessoa de Meia-Idade , Pensões/estatística & dados numéricos , Pessoas com Deficiência Auditiva/estatística & dados numéricos , Desemprego/estatística & dados numéricos
9.
BMC Med Genet ; 21(1): 68, 2020 03 31.
Artigo em Inglês | MEDLINE | ID: mdl-32234020

RESUMO

BACKGROUND: The TWNK gene encodes the twinkle protein, which is a mitochondrial helicase for DNA replication. The dominant TWNK variants cause progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 3, while the recessive variants cause mitochondrial DNA depletion syndrome 7 and Perrault syndrome 5. Perrault syndrome is characterized by sensorineural hearing loss in both males and females and gonadal dysfunction in females. Patients with Perrault syndrome may present early-onset cerebellar ataxia, whereas middle-age-onset cerebellar ataxia caused by TWNK variants is rare. CASE PRESENTATION: A Japanese female born to consanguineous parents presented hearing loss at age 48, a staggering gait at age 53, and numbness in her distal extremities at age 57. Neurological examination revealed sensorineural hearing loss, cerebellar ataxia, decreased deep tendon reflexes, and sensory disturbance in the distal extremities. Laboratory tests showed no abnormal findings other than a moderate elevation of pyruvate concentration levels. Brain magnetic resonance imaging revealed mild cerebellar atrophy. Using exome sequencing, we identified a homozygous TWNK variant (NM_021830: c.1358G>A, p.R453Q). CONCLUSIONS: TWNK variants could cause middle-age-onset cerebellar ataxia. Screening for TWNK variants should be considered in cases of cerebellar ataxia associated with deafness and/or peripheral neuropathy, even if the onset is not early.


Assuntos
Ataxia Cerebelar/genética , DNA Helicases/genética , Proteínas Mitocondriais/genética , Ataxia Cerebelar/complicações , Ataxia Cerebelar/diagnóstico , Consanguinidade , Feminino , Marcha Atáxica/complicações , Marcha Atáxica/diagnóstico , Marcha Atáxica/genética , Disgenesia Gonadal 46 XX/diagnóstico , Disgenesia Gonadal 46 XX/genética , Perda Auditiva/complicações , Perda Auditiva/diagnóstico , Perda Auditiva/genética , Perda Auditiva Neurossensorial/diagnóstico , Perda Auditiva Neurossensorial/genética , Homozigoto , Humanos , Japão , Transtornos de Início Tardio/diagnóstico , Transtornos de Início Tardio/genética , Pessoa de Meia-Idade , Mutação , Linhagem
11.
J Laryngol Otol ; 134(5): 398-403, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32308176

RESUMO

OBJECTIVES: To evaluate the surgical techniques, approaches, audiological outcomes and complications of endoscopic stapes surgery. METHODS: Systematic searches of the literature were performed in PubMed, Web of Science and Scopus databases, to identify studies of patients who underwent stapes surgery using endoscopic approaches and studies reporting objective post-operative hearing outcomes. The following information was extracted: surgery duration, complications, surgical technique and audiometric results. RESULTS: Fourteen studies were selected for appraisal, which included a total of 282 ears subjected to endoscopic stapes surgery. Endoscopic stapes surgery seems to provide adequate visualisation of the middle-ear structures, thereby allowing less invasive surgery and potentially equivalent audiological outcomes as compared with a traditional microscopic approach. Other advantages of endoscopic stapes surgery include decreased surgery time, a reduced need for drilling, and auditory results comparable to those of microscopic techniques. CONCLUSION: Studies have shown that endoscopic stapes surgery has similar surgical and functional advantages as compared with microscopic surgery.


Assuntos
Endoscopia/métodos , Microcirurgia/métodos , Cirurgia do Estribo/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Perda Auditiva/complicações , Perda Auditiva/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Duração da Cirurgia , Otosclerose/complicações , Otosclerose/cirurgia , Complicações Pós-Operatórias/etiologia , Resultado do Tratamento , Adulto Jovem
12.
Acta otorrinolaringol. esp ; 71(1): 45-55, ene.-feb. 2020. graf
Artigo em Espanhol | IBECS | ID: ibc-192435

RESUMO

El objetivo del presente documento es contribuir a la mejora del manejo de la hipoacusia unilateral y de la hipoacusia asimétrica en la infancia. Las sorderas unilaterales afectan a uno por mil de los recién nacidos, aumentando su prevalencia con la edad, debido a los casos de aparición diferida o adquirida. Aunque se ha minimizado el impacto de estas sorderas sobre el desarrollo y los aprendizajes del niño, si no son tratadas provocan secuelas sobre el desarrollo del habla y del lenguaje, así como en el desarrollo global, afectando a la calidad de vida del niño y de su familia. El resultado del trabajo de revisión llevado a cabo se plasma en la formulación de unas recomendaciones orientadas a la mejora clínica diagnóstica y terapéutica de la hipoacusia unilateral y de la hipoacusia asimétrica


The aim of this document is to improve the management and the treatment of unilateral or asymmetrical hearing loss in children. One in one thousand newborn infants has unilateral hearing loss and this prevalence increases with age, due to cases of acquired and delayed-onset hearing loss. Although the impact on the development and learning processes of children of these kinds of hearing loss have usually been minimized, if they are not treated they will impact on language and speech development, as well as overall development, affecting the quality of life of the child and his/her family. The outcomes of the review are expressed as recommendations aimed at clinical diagnosis and therapeutic improvement for unilateral or asymmetrical hearing los


Assuntos
Humanos , Criança , Perda Auditiva Unilateral/diagnóstico , Perda Auditiva Unilateral/terapia , Qualidade de Vida , Perda Auditiva/complicações , Desenvolvimento Infantil , Transtornos da Articulação/complicações , Desempenho Acadêmico , Implantes Cocleares , Diagnóstico Precoce
13.
PLoS One ; 15(1): e0228172, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31978130

RESUMO

Studies have identified prior conditions associated with late-onset Alzheimer's disease dementia (LOAD), but all prior diseases have rarely been screened simultaneously in the literature. Our objective in the present study was to identify prior conditions associated with LOAD and construct pathways for them. We conducted a population-based matched case-control study based on data collected in the National Health Insurance Research database of Taiwan and the Catastrophic Illness Certificate database for the years 1997-2013. Prior diseases definitions were based on the first three digits of the codes listed in the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM). Inclusion criteria required that each ICD-code existed for at least 1 year and incurred at least 2 outpatient visits or inpatient diagnosis. The case group comprised 4,600 patients newly diagnosed with LOAD in 2007-2013. The LOAD patients were matched by sex and age to obtain 4,600 controls. Using stepwise multivariate logistic regression analysis, diseases were screened for 1, 2 …, 9 years prior to the first diagnosis of LOAD. Path analysis was used to construct pathways between prior diseases and LOAD. Our results revealed that the following conditions were positively associated with the incidence of LOAD: anxiety (ICD-code 300), functional digestive disorder (ICD code 564), psychopathology-specific symptoms (ICD-code 307), disorders of the vestibular system (ICD-code 386), concussion (ICD-code 850), disorders of the urethra and urinary tract (ICD-code 599), disorders of refraction and accommodation (ICD-code 367), and hearing loss (ICD-code 389). A number of the prior diseases have previously been described in the literature in a manner identical to that in the present study. Our study supports the assertion that mental, hearing, vestibular system, and functional digestive disorders may play an important role in the pathogenesis of LOAD.


Assuntos
Doença de Alzheimer/diagnóstico , Idoso , Idoso de 80 Anos ou mais , Doença de Alzheimer/epidemiologia , Doença de Alzheimer/etiologia , Ansiedade/complicações , Ansiedade/diagnóstico , Estudos de Casos e Controles , Bases de Dados Factuais , Doenças do Sistema Digestório/complicações , Doenças do Sistema Digestório/diagnóstico , Feminino , Perda Auditiva/complicações , Perda Auditiva/diagnóstico , Humanos , Incidência , Transtornos de Início Tardio , Masculino , Taiwan/epidemiologia , Doenças Uretrais/complicações , Doenças Uretrais/diagnóstico
14.
BMC Med Genet ; 21(1): 13, 2020 01 14.
Artigo em Inglês | MEDLINE | ID: mdl-31937257

RESUMO

BACKGROUND: Mutations of the WFS1 gene are responsible for most cases of Wolfram syndrome (WS), a rare, recessively inherited neurodegenerative disorder characterized by juvenile-onset non-autoimmune diabetes mellitus and optic atrophy. Variants of WFS1 are also associated with non-syndromic hearing loss and type-2 diabetes mellitus (T2DM). Our study adds to literature significant associations between WS and T2DM. CASE PRESENTATION: In this study, we analyzed the clinical and genetic data of two families with high prevalence of WS and T2DM. Genetic linkage analysis and DNA sequencing were exploited to identify pathogenic variants. One novel pathogenic variant (c.2243-2244insC) and one known pathogenic (c.1232_1233delCT) (frameshift) variant were identified in exon eight of WFS1 gene. CONCLUSIONS: The mutational and phenotypic spectrum of WS is broadened by our report of novel WFS1 mutation. Our results reveal the value of molecular analysis of WFS1 in the improvement of clinical diagnostics for WS. This study also confirms the role of WFS1 in T2DM.


Assuntos
Diabetes Mellitus Tipo 2/genética , Testes Genéticos , Proteínas de Membrana/genética , Síndrome de Wolfram/genética , Adulto , Criança , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/patologia , Éxons/genética , Feminino , Mutação da Fase de Leitura/genética , Ligação Genética , Predisposição Genética para Doença , Perda Auditiva/complicações , Perda Auditiva/genética , Perda Auditiva/patologia , Humanos , Irã (Geográfico)/epidemiologia , Masculino , Atrofia Óptica/complicações , Atrofia Óptica/genética , Atrofia Óptica/patologia , Linhagem , Fenótipo , Mutação Puntual/genética , Síndrome de Wolfram/complicações , Síndrome de Wolfram/patologia , Adulto Jovem
15.
Int J Pediatr Otorhinolaryngol ; 131: 109862, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31927148

RESUMO

OBJECTIVES: To evaluate the association between torticollis and enlarged vestibular aqueduct (EVA). METHODS: An online/phone survey was administered to parents of 133 children diagnosed with the following disorders: EVA, GJB2 (Connexin 26) mutations associated congenital hearing loss and epistaxis (control). The survey included questions regarding symptoms of torticollis, vertigo, and hearing loss. RESULTS: Patients with EVA had a 10-fold greater odds of having torticollis than controls (31% vs. 4%; OR = 10.6; 95% CI: 2.9, 39.2). No patients with GJB2 had a reported history of torticollis. Torticollis preceded the diagnosis of hearing loss in most (87%) patients with EVA who had a reported history of torticollis. EVA patients were more likely to have reported motor delay than controls (40% vs. 15%; p = 0.002). EVA patients with prior torticollis (80%; 12/15) were more likely to have balance impairment than EVA patients without prior torticollis (12%; 4/33; p < 0.001). Twelve patients had a reported history of paroxysmal torticollis, all of whom had EVA. CONCLUSION: Torticollis in infants may be a marker of EVA. Infants with torticollis should be monitored closely for hearing loss and motor delay, especially when the torticollis is paroxysmal.


Assuntos
Perda Auditiva Neurossensorial/complicações , Perda Auditiva/congênito , Torcicolo/complicações , Aqueduto Vestibular/anormalidades , Estudos de Casos e Controles , Conexina 26 , Conexinas/genética , Feminino , Perda Auditiva/complicações , Humanos , Lactente , Masculino , Mutação , Estudos Retrospectivos , Vertigem/etiologia
16.
Int J Pediatr Otorhinolaryngol ; 130: 109813, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31891830

RESUMO

Monitoring the effects of Hearing Loss on Quality of Life, which is frequently seen on children and causes inefficiency in speech, education, and social development, is not only important for listening skills, using hearing devices, and linguistic and speech skills but also important for the treatment. And, if no treatment possible, then it is also critical for rehabilitation with different equipment. By making use of the Quality of Life Questionnaire, developed by Streufert at University of Washington in 2008 to Turkish and Turkish culture, this study was conducted in order to assess the effect of hearing loss of children between the age of 7 and 12 on their quality of life, as well as determining the effects of the hearing loss-related variables on the quality of life. The study was carried out on 115 kids between the ages of 7 and 12; 35 with unilateral HL, 45 with bilateral HL, and 35 of them without any hearing loss. The questionnaire was named ISYAK (Isitme Kayiplilar için Yasam Kalitesi Ölçegi - as with Turkish initials - Quality of Life Questionnaire for Hearing Loss). If the ISYAK was confirmed on the sample in Turkish culture was examined by using Confirmatory Factor Analysis (CFA). In addition to CFA, the data obtained from the ISYAK and Quality of Life Scale for Children (ÇIYKÖ) were compared by using variance analysis, and it was determined that there were significant differences between the normally hearing children and the children having hearing loss in terms of school, physical activity scores of ÇIYKÖ and all the dimensions of ISYAK (environment, activity, emotions). In conclusion, besides the general similarities with the results obtained from the study on developing ISYAK, differences were observed in the demographic variables. The statistical analyses conducted on ISYAK showed that ISYAK can be used both in clinical and as well as in rehabilitation centers as a special questionnaire for determining the quality of life for the kids with hearing loss with reliable and valid results.


Assuntos
Perda Auditiva/psicologia , Qualidade de Vida , Fatores Etários , Criança , Feminino , Perda Auditiva/complicações , Testes Auditivos , Humanos , Idioma , Masculino , Inquéritos e Questionários , Turquia
17.
J Plast Surg Hand Surg ; 54(1): 6-13, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31393744

RESUMO

Internationally adopted children (IAC) with a cleft lip and/or palate (CL/P) tend to arrive with un-operated palates at an age at which their Swedish-born peers have completed their primary palate surgery. Our aim of the present study was to analyze surgical, speech and hearing outcomes of IAC at age 5 and compare with those of a matched group of Swedish-born children. Fifty children with CL/P born in 1994-2005 participated in the study. Twenty-five IAC were matched according to age, sex and cleft type with 25 Swedish-born children. Audio recordings were perceptually analyzed by two experienced, blinded speech-language pathologists. Hearing and speech statuses were evaluated on the same day for all children. Surgical timing and complications as in fistulas and requirement for secondary velopharyngeal (VP) surgery, speech evaluation results, and present hearing status were analyzed for all children of age 5 years. Results showed that primary palatal surgery was delayed by a mean of 21 months in IAC. IAC had a higher prevalence of velopharyngeal impairment that was statistically significant, a higher fistula rate, and experienced more secondary surgery than Swedish-born peers. Hearing loss due to middle ear disease was slightly more common among IAC, whereas the rate of treatment with tympanostomy tubes was similar between the two groups. In conclusion, IAC with CL/P represent a challenge for CL/P teams because of the heterogeneous nature of the patient group and difficulties associated with delayed treatment, and the results show the importance of close follow-up over time.


Assuntos
Criança Adotada , Fenda Labial/cirurgia , Fissura Palatina/cirurgia , Pré-Escolar , Fenda Labial/complicações , Fissura Palatina/complicações , Feminino , Perda Auditiva/complicações , Humanos , Internacionalidade , Masculino , Ventilação da Orelha Média/estatística & dados numéricos , Fístula Bucal/complicações , Reoperação/estatística & dados numéricos , Suécia , Tempo para o Tratamento , Insuficiência Velofaríngea/complicações
18.
Am J Otolaryngol ; 41(2): 102377, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31864727

RESUMO

BACKGROUND: Hearing loss and hearing handicap may contribute to cognitive impairment and dementia. The purpose of this study was to analyze the association between hearing loss and hearing handicap with dementia in an Asian memory clinic parents. METHODS: This study includes the data obtained from patients with mild dementia who attended the National University hospital memory clinic and non-demented healthy subjects among spouses and caregivers who are non-genetically related to our patients. All participants underwent comprehensive physical, medical, neuropsychological and audiological assessments (i.e. pure tone audiometry - PTA). Disabling hearing loss was defined as a hearing loss of >40 dB in the better ear on PTA. Amsterdam Inventory for Auditory Disability and Handicap (AIADH) questionnaire was administered through the verbal interview to measure their hearing handicap score. Linear regression models were used to investigate the association between hearing loss and hearing handicap with dementia. Mean differences (ß) with 95% confidence intervals (CI) were calculated. RESULTS: 91 participants (65-90 years old) were recruited for this study; 39 of them were patients with dementia and 52 were non-demented healthy controls. 48.7% of the patients with dementia had disabling hearing loss, which is higher than the non-demented controls (25.0%) (p = 0.019). The significant association between hearing handicap (as measured by AIADH) and dementia was observed, which was independent of demographic factors and audiology related history and PTA average (ß = -6.40; 95% CI =0.11.99, -0.81, p = 0.025). There was no independent association between hearing loss and dementia (p > 0.05). CONCLUSION: A significant association between hearing handicap and dementia was found. The mechanism of this association requires further research and may involve higher order central processing disorder.


Assuntos
Demência/etiologia , Pessoas com Deficiência , Perda Auditiva/complicações , Idoso , Grupo com Ancestrais do Continente Asiático , Demência/epidemiologia , Feminino , Perda Auditiva/diagnóstico , Perda Auditiva/epidemiologia , Humanos , Masculino , Inquéritos e Questionários
19.
Otol Neurotol ; 41(1): 25-32, 2020 01.
Artigo em Inglês | MEDLINE | ID: mdl-31634278

RESUMO

OBJECTIVE: The purpose of the present study was to estimate the risk of mortality in hearing loss subjects in accordance with the cause of death. STUDY DESIGN: A longitudinal follow up study. SETTING: Data from the Korean National Health Insurance Service-National Sample Cohort were collected from a period between 2002 and 2013. PATIENTS AND INTERVENTION: The 4,606 severe and 1,007 profound hearing loss participants with 40 or more years old were 1:4 matched with control participants, respectively, for age, sex, income, and region of residence. The causes of death were grouped into 12 classifications. MAIN OUTCOME MEASURES: The ratio of mortality was compared between the hearing loss and control group using a χ test or Fisher's exact test. In a Cox-proportional hazard model, age, sex, income, region of residence, and past medical histories were considered confounders. RESULTS: The severe and profound hearing loss groups showed 4.07 (95% CI = 3.71-4.46, p < 0.001) and 4.22 times (95% CI = 3.52-5.05, p < 0.001) higher mortality ratios in the adjusted models, respectively. Both the severe and profound hearing loss groups showed higher mortality by infection, neoplasm, trauma, and metabolic, mental, circulatory, respiratory, and digestive diseases than control groups (p < 0.05). Among various causes of death, death by trauma revealed the highest odds ratios in both the severe and profound hearing loss groups. CONCLUSION: Hearing loss was associated with a significant increase in mortality.


Assuntos
Causas de Morte , Perda Auditiva/mortalidade , Adulto , Idoso , Estudos de Coortes , Feminino , Seguimentos , Perda Auditiva/complicações , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Razão de Chances , Modelos de Riscos Proporcionais
20.
Ig Sanita Pubbl ; 75(4): 297-301, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31887735

RESUMO

A 65-year-old woman affected by chronic pruritus in both ears was referred by her family physician to a private laboratory to undergo an ear swab test for microbiological and cultural examination. During the procedure on the right side, the patient experienced sudden pain, immediately followed by auricular fullness and dizziness. The clinician performing the swab did not perform an otoscopy and did not administer any topical or general medications. A few days later, purulent discharge appeared. Follow-up showed tympanic membrane perforation and mixed severe hearing loss. Indications for ear swab tests are currently unclear, and complications deriving from this apparently simple procedure are seldom reported.


Assuntos
Perda Auditiva/complicações , Jurisprudência , Erros Médicos , Otite Média/complicações , Perfuração da Membrana Timpânica , Idoso , Feminino , Humanos , Ruptura Espontânea
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA