Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 6.975
Filtrar
1.
Sci Rep ; 12(1): 13826, 2022 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-35970916

RESUMO

This study assessed the regional diversity of the human cranial form by using geometric homologous models based on scanned data from 148 ethnic groups worldwide. This method adopted a template-fitting technique for a nonrigid transformation via the iterative closest point algorithm to generate the homologous meshes. Through the application of principal component analysis to 342 sampled homologous models, the largest variation was detected in overall size, and small South Asian crania were clearly verified. The next greatest diversity was found in the length/breadth proportion of the neurocranium, which showed the contrast between the elongated crania of Africans and the globular crania of Northeast Asians. Notably, this component was slightly correlated with the facial profile. Well-known facial features, such as the forward projection of the cheek among Northeast Asians and compaction of the European maxilla, were reconfirmed. These facial variations were highly correlated with the calvarial outline, particularly the degree of frontal and occipital inclines. An allometric pattern was detected in facial proportions in relation to overall cranial size; in larger crania, the facial profiles tend to be longer and narrower, as demonstrated among many American natives and Northeast Asians. Although our study did not include data on environmental variables that are likely to affect cranial morphology, such as climate or dietary conditions, the large datasets of homologous cranial models will be usefully available for seeking various attributions to phenotypic skeletal characteristics.


Assuntos
Face , Crânio , Pesos e Medidas Corporais , Clima , Face/anatomia & histologia , Humanos , Análise de Componente Principal , Crânio/anatomia & histologia
2.
Surg Radiol Anat ; 44(7): 1029-1036, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-35840762

RESUMO

PURPOSE: The aim of our study was to determine the variations of the anterior branches of the external carotid artery (ECA) and investigate the morphometric and geometric features of the anterior branches of the ECA and carotid bifurcation (CB). METHODS: A total of 563 ECAs were included from 288 patients in the study. Classification and exit angles of anterior branches of ECA and determination of vertebral levels of CB and anterior branches were performed. RESULTS: The anterior branch variants of the ECA were observed in 8 different subgroups. The most common variations were type Ia 42.3% (n = 120) on the right and type Ib 40.9% (n = 114) on the left. When looking at the vertebral levels, CB was detected at C4 level in 32.9% of total ECAs (n = 185), STA was at C4 level in 33.4% of total ECAs (n = 188), LA was at C3 level in 50.1% of total ECAs (n = 282), and FA was at C2 level in 37.3% of total ECAs. The mean CB angle in all cases was 59.93° ± 16.04. In the anterior branches of the ECA in cases belonging to the Type I group, the widest angle belonged to FA (R = 116.88 ± 27.04°, L = 110.32° ± 25.94). CONCLUSION: In conclusion, a new classification of the variations of the anterior branches of the ECA was made on the basis of the CTA images to gain more practicality in surgical procedures. This study revealed for the first time the angular and level relationship between CB and ECA anterior branches.


Assuntos
Artéria Carótida Externa , Estenose das Carótidas , Pesos e Medidas Corporais , Artérias Carótidas , Artéria Carótida Externa/diagnóstico por imagem , Angiografia por Tomografia Computadorizada , Humanos , Pescoço
3.
Niger J Clin Pract ; 25(5): 653-663, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-35593609

RESUMO

Background: The female breast is a symbol of femininity and aesthetics having a great psychosocial impact on the woman's sense of wellbeing and self-esteem. To optimize satisfaction of patients in cosmetic and reconstructive breast surgeries, there is a need to define the dominant breast size and shape that connotes feminine attractiveness. This necessitates the knowledge of ideal data for normal nulliparous female breast parameters and volume for various body sizes in the particular population, nationality, and race. Aim: To establish reference data for normal breast parameters and volumes for the various body sizes amongst the Nigerian population and to determine their relationships with other body parameters. Patients and Methods: A total of 528 breasts from 264 Nigerian undergraduate post-menarcheal nulliparous students of the University of Nigeria Enugu Campus aged between 17 and 29 years were measured. Thirty-one (31) anthropomorphic parameters and five body size anthropometric indicators were measured. Data obtained were analyzed using Statistical Package for Social Sciences (SPSS) version 21(IBM) and were summarized using various descriptive statistics tools. Results: The mean nipple-nipple distance is 23.37 ± 3.10. The mean left Midclavicle-nipple Length (22.17 ± 3.5 cm) is significantly (P = 0.04) higher than the right (21.79 ± 3.3 cm) just as the mean left (12.60 ± 2.5) medial radius is significantly (P = 0.0001) longer than the right (12.45 ± 2.4 cm). The mean left nipple projection (0.37 ±0.2 cm) and left vertical surface dimension (32.27 ± 5.7 cm) are significantly (P > 0.05) longer than the right (0.33 ±0.2) and (31.76 ± 5.2 cm). Also the mean volume for the left breast (605.26 ± 280.52 cm) is significantly (0.0001) higher than that of the right breast (592.53 ± 278.69). Breast volume correlated well with most of the breast parameters, BMI, and other anthropometric variables. Most breasts were ptotic (51%, 55%), especially the left breasts. Breast dimensions were asymmetrical in >50% of subjects, where the left breasts were seen to have slightly greater breast dimensions than right. Conclusion: Breast values and related body size parameters were noted to be comparatively higher than earlier reported values mostly for the Asian population.


Assuntos
Mamoplastia , Adolescente , Adulto , Tamanho Corporal , Pesos e Medidas Corporais , Feminino , Humanos , Mamoplastia/métodos , Nigéria , Mamilos/cirurgia , Adulto Jovem
4.
Surg Radiol Anat ; 44(6): 925-932, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35543750

RESUMO

PURPOSE: The computed tomography (CT) study investigates the olfactory fossa (OF) morphometry and morphology. METHODS: Fifty Greek adult dried skulls were macroscopically investigated for the detection of the OF morphological patterns and after a multiplanar CT reconstruction, the OF morphometry was accurately calculated using a digital ruler. RESULTS: Types I and II surface contour patterns were the most frequently identified (36 and 32%), followed by types III, IV, and V (16, 12, and 4%). Crista galli mean length, height, and width were 19.46 ± 2.34 mm, 12.69 ± 2.7 mm, and 5.18 ± 1.11 mm. The OF mean maximum length was 22.29 ± 2.16 mm on the right and 22.10 ± 2.44 mm on the left side, and symmetry was detected. The OF median values of the maximum depth for its anterior, middle, and posterior third were 4.91 mm, 4.72 mm, and 2.78 mm on the right and 4.55 mm, 4.75 mm, and 2.55 mm on the left side. Symmetry was observed in any third of the OF. The OF median values of the surface maximum width for the anterior, middle, and posterior thirds were 9.29 mm, 11.48 mm, and 13.07 mm. A significant gradual increase of the OF surface maximum width was detected in the anteroposterior direction in the total sample (p < 0.001), with the highest value (23.12 mm) in the posterior third. A significant (p < 0.001) very strong (rs = -0.798) and a moderate (rs = -0.524) negative linear correlation in the OF anterior and middle third were, respectively, identified between its maximum depth and width. No gender impact was identified. CONCLUSIONS: The study helps to familiarize with the calculation of the OF dimensions and simplifies the understanding of its complex anatomy, to reach successful surgical planning and minimize perioperative complications.


Assuntos
Osso Etmoide , Tomografia Computadorizada por Raios X , Adulto , Pesos e Medidas Corporais , Osso Etmoide/anatomia & histologia , Humanos
5.
Surg Radiol Anat ; 44(6): 933-940, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35546361

RESUMO

OBJECTIVE: To reveal the anatomical relationships of the ethmoid roof on CT in pediatric case group. METHODS: We measured the depth of olfactory fossa (DOF), the width of olfactory fossa (WOF), the angle between lateral lamella and cribriform plate (LLCPA), the width of the olfactory cleft (WOC), the length of lateral lamella (LLL), orbital roof fovea to ethmoidal distance (ORFED) and orbital roof to cribriform plate distance (ORCPD) and we determined Keros and LLCPA types from paranasal sinus CT of subjects under 16 years of age retrospectively. RESULTS: The incidence of Keros type I was higher in females and Keros Type II in males. The ORCPD, DOF and LLL values were found to be higher in 13-16 years age group and WOF and LLCPA in 4-6 years age group. The prevalence of Keros type II was higher in the 13-16 age group, and Keros type I was higher in other age groups. LLCPA type A was the most frequent in all age groups and in both sexes. There was a positive correlation between age and ORCPD, DOF, LLL, and a negative correlation with ORFED, WOF, LLCPA. Olfactory fossa width and depth had a negative correlation. LLCPA had a positive correlation with WOF and a negative correlation with DOF. There was a positive correlation between LLCPA and LLL. DOF and LLL had a positive correlation too. CONCLUSIONS: Paranasal sinus CT provides useful information about frontal skull base anatomic relations before sinus surgery in pediatric cases.


Assuntos
Osso Etmoide , Base do Crânio , Pesos e Medidas Corporais , Criança , Pré-Escolar , Osso Etmoide/diagnóstico por imagem , Seio Etmoidal/diagnóstico por imagem , Feminino , Humanos , Masculino , Estudos Retrospectivos , Base do Crânio/anatomia & histologia , Tomografia Computadorizada por Raios X/métodos
7.
Int. j. cardiovasc. sci. (Impr.) ; 35(2): 191-201, Mar.-Apr. 2022. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1364978

RESUMO

Abstract Background Physical Fitness Tests (PFTs) are part of military routines and are usually administered to applicants for the Brazilian corps member, including the civil police. Objective To identify in the literature, scientific articles aimed at assessing physical fitness of police and military personnel in Brazil, using PFTs. Methods This was a systematic review, using the PRISMA systematization, using the following search keywords "police", "military", "physical fitness test" and " PFT", in English and Portuguese. The databases used were ScienceDirect, PubMed, BVS (Lilacs) and Scielo. Only original works performed with police and military personnel in Brazil were selected, through the application of inclusion and exclusion criteria. Results After the screening process, 11 articles were selected from a total of 1,487. Conclusions The data collected from the selected articles suggest that older age is related to a decrease in physical fitness, and better performance in the tests is related to a lower risk of comorbidities. Although high-intensity training improves physical fitness and anthropometric data, it is associated with injury rates; physically active lifestyle is associated with better flexibility.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Adulto Jovem , Aptidão Física , Polícia , Teste de Esforço/métodos , Militares , Pesos e Medidas Corporais , Brasil , Exercício Físico , Comorbidade , Fatores de Risco , Fatores Etários , Saúde Militar , Estilo de Vida
8.
PLoS One ; 17(3): e0265255, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35271672

RESUMO

Traditional body measurement techniques are commonly used to assess physical health; however, these approaches do not fully represent the complex shape of the human body. Three-dimensional (3D) imaging systems capture rich point cloud data that provides a representation of the surface of 3D objects and have been shown to be a potential anthropometric tool for use within health applications. Previous studies utilising 3D imaging have only assessed body shape based on combinations and relative proportions of traditional body measures, such as lengths, widths and girths. Geometric morphometrics (GM) is an established framework used for the statistical analysis of biological shape variation. These methods quantify biological shape variation after the effects of non-shape variation-location, rotation and scale-have been mathematically held constant, otherwise known as the Procrustes paradigm. The aim of this study was to determine whether shape measures, identified using geometric morphometrics, can provide additional information about the complexity of human morphology and underlying mass distribution compared to traditional body measures. Scale-invariant features of torso shape were extracted from 3D imaging data of 9,209 participants form the LIFE-Adult study. Partial least squares regression (PLSR) models were created to determine the extent to which variations in human torso shape are explained by existing techniques. The results of this investigation suggest that linear combinations of body measures can explain 49.92% and 47.46% of the total variation in male and female body shape features, respectively. However, there are also significant amounts of variation in human morphology which cannot be identified by current methods. These results indicate that Geometric morphometric methods can identify measures of human body shape which provide complementary information about the human body. The aim of future studies will be to investigate the utility of these measures in clinical epidemiology and the assessment of health risk.


Assuntos
Pesos e Medidas Corporais , Tronco , Adulto , Antropometria , Feminino , Humanos , Imageamento Tridimensional , Masculino , Matemática
9.
BMC Vet Res ; 18(1): 97, 2022 Mar 11.
Artigo em Inglês | MEDLINE | ID: mdl-35277171

RESUMO

BACKGROUND: Sheep (Ovis aries) have been largely used as animal models in a multitude of specialties in biomedical research. The similarity to human brain anatomy in terms of brain size, skull features, and gyrification index, gives to ovine as a large animal model a better translational value than small animal models in neuroscience. Despite this evidence and the availability of advanced imaging techniques, morphometric brain studies are lacking. We herein present the morphometric ovine brain indexes and anatomical measures developed by two observers in a double-blinded study and validated via an intra- and inter-observer analysis. RESULTS: For this retrospective study, T1-weighted Magnetic Resonance Imaging (MRI) scans were performed at 1.5 T on 15 sheep, under general anaesthesia. The animals were female Ovis aries, in the age of 18-24 months. Two observers assessed the scans, twice time each. The statistical analysis of intra-observer and inter-observer agreement was obtained via the Bland-Altman plot and Spearman rank correlation test. The results are as follows (mean ± Standard deviation): Indexes: Bifrontal 0,338 ± 0,032 cm; Bicaudate 0,080 ± 0,012 cm; Evans' 0,218 ± 0,035 cm; Ventricular 0,241 ± 0,039 cm; Huckman 1693 ± 0,174 cm; Cella Media 0,096 ± 0,037 cm; Third ventricle ratio 0,040 ± 0,007 cm. Anatomical measures: Fourth ventricle length 0,295 ± 0,073 cm; Fourth ventricle width 0,344 ± 0,074 cm; Left lateral ventricle 4175 ± 0,275 cm; Right lateral ventricle 4182 ± 0,269 cm; Frontal horn length 1795 ± 0,303 cm; Interventricular foramen left 1794 ± 0,301 cm; Interventricular foramen right 1,78 ± 0,317 cm. CONCLUSIONS: The present study provides baseline values of linear indexes of the ventricles in the ovine models. The acquisition of these data contributes to filling the knowledge void on important anatomical and morphological features of the sheep brain.


Assuntos
Ventrículos do Coração , Imageamento por Ressonância Magnética , Animais , Pesos e Medidas Corporais/veterinária , Feminino , Imageamento por Ressonância Magnética/métodos , Imageamento por Ressonância Magnética/veterinária , Estudos Retrospectivos , Ovinos
11.
Sci Rep ; 12(1): 5259, 2022 03 28.
Artigo em Inglês | MEDLINE | ID: mdl-35347174

RESUMO

The sphenoid has a complicated shape, and its morphogenesis during early development remains unknown. We aimed to elucidate the detailed morphogenesis of the sphenoid and to visualize it three-dimensionally using histological section (HS) and phase-contrast X-ray CT (PCX-CT). We examined 54 specimens using HS and 57 specimens using PCX-CT, and summarized the initial morphogenesis of the sphenoid during Carnegie stage (CS) 17 to 23. The 3D models reconstructed using PCX-CT demonstrated that some neural foramina have the common process of "neuro-advanced" formation and revealed that shape change in the anterior sphenoid lasts longer than that of the posterior sphenoid, implying that the anterior sphenoid may have plasticity to produce morphological variations in the human face. Moreover, we measured the cranial base angle (CBA) in an accurate midsagittal section acquired using PCX-CT and found that the CBA against CS was largest at CS21. Meanwhile, CBA against body length showed no striking peak, suggesting that the angulation during the embryonic period may be related to any developmental events along the progress of stages rather than to a simple body enlargement. Our study elucidated the normal growth of the embryonic sphenoid, which has implications for the development and evolution of the human cranium.


Assuntos
Pesos e Medidas Corporais , Base do Crânio , Cabeça , Humanos , Morfogênese , Radiografia
12.
Growth Horm IGF Res ; 63: 101457, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-35334425

RESUMO

This is the story of a giant who lived in Abruzzo 200 years ago. He became a symbol for his people and a strong resilience generator. Gigantism, in the history of humanity has always attracted attention, albeit passing over the centuries from myth, from divinity to the freak phenomenon, the freak of nature that becomes a spectacle to show off. The attraction for understanding the pathophysiological mechanisms underlying gigantism developed by the end of 19th century. Increased levels of growth hormone (GH) or insulin-like growth hormone 1 (IGF1) causes overgrowth in pituitary gigantism. The imposing size of the body, in our imagination, represents strength and health, reason why in our imagination it almost becomes a divine mythical image. The story of the Acciano's Giant represents a cultural heritage that passes from one generation to the next, that contributes in giving a sense of identity and continuity. It provides a link from past to present and to the future. Encourages a sense of identity and responsibility contributing to social cohesion, helping individuals to feel members of one community. A disease, represented by the Giant, has become a symbol capable of bringing the community together and giving it the strength to react to environment, nature and history. This is a lesson that teaches us the sense of community.


Assuntos
Gigantismo , Hormônio do Crescimento Humano , Pesos e Medidas Corporais , Hormônio do Crescimento , Humanos , Masculino
13.
Chemosphere ; 295: 133947, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-35151700

RESUMO

Morphological characteristics are the leading indicators of the health status of birds. To explore the effects of heavy metals on bird morphometry in natural populations, tree sparrows (Passer montanus) were studied in a polluted site [Baiyin (BY)] and a relatively unpolluted site [Liujiaxia (LJX)]. This study aimed to examine whether morphological variables, the fluctuating asymmetry (FA) of the wing, tarsus, and toe length, were associated with heavy metals (Cu, Zn, Pb, and Cd) and Ca levels in different tissues and feces of adults and nestlings. Results showed that adults collected from BY contained relatively higher heavy metal concentrations and lower Ca concentrations in different tissues than those from LJX. Smaller body sizes and higher FA levels of adults and nestlings were found in BY than in LJX. Although higher heavy metal concentrations in some tissues were associated with smaller morphological characteristics of adults, the effects were not obvious in nestlings. The most correlated heavy metal with as many characteristics was heavy metal in primary feather in both sites, and the most affected characteristic was body mass in BY. The FA values of adults and nestlings in BY were positively affected by heavy metal concentrations in different tissues and feces. The growth rate of wing and tarsus length of nestlings in BY were negatively affected by the FA values of wing and tarsus length, respectively. Taken together, environmental metal pollution might affect the morphological characteristics of tree sparrows. These findings suggest that the morphological characteristics of tree sparrows, especially FA, can be used as indicators of metal pollution, underscoring the importance of measuring morphological characteristics in avian ecotoxicology field studies.


Assuntos
Metais Pesados , Pardais , Animais , Pesos e Medidas Corporais , Monitoramento Ambiental/métodos , Poluição Ambiental/análise , Plumas/química , Metais Pesados/análise , Metais Pesados/toxicidade
14.
Sci Rep ; 12(1): 2551, 2022 02 15.
Artigo em Inglês | MEDLINE | ID: mdl-35169240

RESUMO

Shorter people are at risk for cardiovascular disease (CVD), but data remain limited. This study sought to determine whether height loss is associated with an increased incidence of CVD. From the Korean National Health Insurance Service-Senior database (2002-2015), data of 134,952 individuals with available information on height loss was obtained. Height loss as percentages was measured 3-5 years from the baseline height. To assess hazard ratios for CVD incidence, multivariable Cox proportional hazard regression models were used before and after applying propensity score matching. The unmatched cohort consisted of 109,546 participants without height loss (< 1%): 20,208 participants with 1-2% height loss, and 5126 participants with ≥ 2% height loss. During a median follow-up period of 6.5 years (interquartile range, 3.7-8.5 years), 21,921 were newly diagnosed with CVD. Adults with height loss of > 2% had a greater risk of incident CVD than those with no height loss. This finding was statistically significant both in the original- and propensity score-matched cohorts. The increased risk for ischemic stroke was significant in the male subgroups, in line with degree of height loss. Overall, height loss is associated with an increased risk of subsequent ischemic stroke in Korean men.


Assuntos
Pesos e Medidas Corporais , Doenças Cardiovasculares/epidemiologia , Idoso , Estudos de Coortes , Feminino , Humanos , Incidência , Masculino , República da Coreia/epidemiologia , Fatores de Risco
15.
Comput Math Methods Med ; 2022: 5600804, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35126628

RESUMO

BACKGROUND: Lymphedema is a common complication of breast cancer treatment, affecting 1/5 of breast cancer survivors, but there is no reliable way to detect subclinical lymphedema. OBJECTIVE: The purpose of this study was to determine the feasibility and reliability of using an oversleeve as a postoperative limb volume measurement tool in breast cancer patients. METHODS: Fifty patients were analyzed based on inclusion criteria. A body volume measurement kit was designed based on the drainage volume method and the circumference measurement method. Twenty-two normal healthy people were measured by the drainage volume (LV) and oversleeve measuring limb volume (OMLV) methods, so as to verify the accuracy of OMLV. Twenty-eight patients with lymphedema diagnosed by the circumdiameter measurement (CDM) method were measured with OMLV for comparison. The difference in measurements between OMLV and CDM was compared in 50 patients with early lymphedema diagnosed by the LV method. RESULTS: There was no significant difference between the sleeve method and the drainage volume method in the normal population (P = 0.74). All patients with lymphedema diagnosed by CDM met the diagnostic criteria by the OMLV method. In patients with early lymphedema diagnosed by LV, the diagnostic rate with OMLV was significantly higher than that with CDM (P = 0.008). CONCLUSION: Similar to LV in the diagnosis of lymphedema, OMLV can effectively improve the diagnostic rate of early lymphedema, providing a new option for the diagnosis and treatment of lymphedema.


Assuntos
Pesos e Medidas Corporais/instrumentação , Linfedema Relacionado a Câncer de Mama/patologia , Neoplasias da Mama/patologia , Extremidade Superior/patologia , Adulto , Idoso , Pesos e Medidas Corporais/métodos , Pesos e Medidas Corporais/estatística & dados numéricos , Linfedema Relacionado a Câncer de Mama/diagnóstico , Neoplasias da Mama/cirurgia , Biologia Computacional , Feminino , Humanos , Pessoa de Meia-Idade , Tamanho do Órgão , Valores de Referência , Têxteis
16.
Braz J Biol ; 84: e257023, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35195173

RESUMO

The present study examines the correlations between fifteen morphometric and ten meristic characters and total length (TL) of males, females, and combined sexes of Alepes vari (Cuvier, 1833) collected from Karachi fish harbor, West Wharf of Karachi Coast. Statistical analyses of linear regression relationships show mostly strong correlations (r≥0.70; p<0.05) between total length (TL) and most morphometric characters in males, females, and combined sexes, except the height of pectoral-fin (PFH), and pelvic-fin base length (PelFL); whereas, meristic characters were found to be constant and indicate weak or negative type correlations (r≤0.50; p>0.05) with total length (TL). Hence, according to our present results, there is a direct relationship between the total length of fish and all morphometric characters, which were found to be the best indicators of positive allometric pattern growth in fish. Moreover, analysis of the 2-sample t-test revealed (t-test; p>0.05) that no sexual dimorphism was reported in Alepes vari. Thus, our present study could be valuable in systematic classification, sexual dimorphism, and management of this species on the Karachi coast.


Assuntos
Pesos e Medidas Corporais , Peixes , Animais , Feminino , Masculino , Caracteres Sexuais
17.
PLoS One ; 17(1): e0249803, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35100275

RESUMO

Participation in women's rugby league has been growing since the foundation of the English women's rugby league Super League in 2017. However, the evidence base to inform women's rugby league remains sparse. This study provides the largest quantification of anthropometric and physical qualities of women's rugby league players to date, identifying differences between positions (forwards & backs) and playing level (Women's Super League [WSL] vs. International). The height, weight, body composition, lower body strength, jump height, speed and aerobic capacity of 207 players were quantified during the pre-season period. Linear mixed models and effects sizes were used to determine differences between positions and levels. Forwards were significantly (p < 0.05) heavier (forwards: 82.5 ± 14.8kg; backs: 67.7 ± 9.2kg) and have a greater body fat % (forwards: 37.7 ± 6.9%; backs: 30.4 ± 6.3%) than backs. Backs had significantly greater lower body power measured via jump height (forwards: 23.5 ± 4.4cm; backs: 27.6 ± 4.9cm), speed over 10m (forwards: 2.12 ± 0.14s; backs: 1.98 ± 0.11s), 20m (forwards: 3.71 ± 0.27s; backs: 3.46 ± 0.20s), 30m (forwards: 5.29 ± 0.41s; backs: 4.90 ± 0.33s), 40m (forwards: 6.91 ± 0.61s; backs: 6.33 ± 0.46s) and aerobic capacity (forwards: 453.4 ± 258.8m; backs: 665.0 ± 298.2m) than forwards. Additionally, international players were found to have greater anthropometric and physical qualities in comparison to their WSL counterparts. This study adds to the limited evidence base surrounding the anthropometric and physical qualities of elite women's rugby league players. Comparative values for anthropometric and physical qualities are provided which practitioners may use to evaluate the strengths and weaknesses of players, informing training programs to prepare players for the demands of women's rugby league.


Assuntos
Pesos e Medidas Corporais/estatística & dados numéricos , Aptidão Física , Adulto , Composição Corporal , Estatura , Peso Corporal , Feminino , Humanos , Força Muscular , Corrida , Adulto Jovem
18.
Plast Reconstr Surg ; 149(2): 248e-253e, 2022 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-35077422

RESUMO

BACKGROUND: Left clefts occur twice as frequently as right ones. The sidedness has been suggested to influence certain outcomes. Some surgeons consider a right cleft more challenging to repair. This is often attributed to their reduced prevalence. The authors question whether this may be caused by morphologic differences. The authors' hypothesis is that there are anthropometric differences between left and right complete cleft lips. METHODS: Patients with complete unilateral cleft lip, with or without cleft palate, operated on at the age of 3 to 6 months, between 2000 and 2018, by a single surgeon, were included. Eight standardized anthropometric measurements of the cleft lip, collected just before cleft lip repair, compare lip and vermillion dimensions and ratios between left and right clefts. RESULTS: One hundred thirty-nine left and 80 right unilateral cleft lips were compared. A significant difference was found between left and right clefts for cleft-side to non-cleft-side ratios comparing the lateral lip element vertical heights and vermillion heights. CONCLUSIONS: Patients with right cleft lips have a greater degree of lateral lip element hypoplasia, demonstrating greater deficiencies of lateral lip element vertical height and vermillion height when compared to patients with left clefts. This has clinical implications for preoperative assessment, choice of surgical technique, and postoperative and long-term outcomes.


Assuntos
Fenda Labial/patologia , Fissura Palatina/patologia , Pesos e Medidas Corporais , Fenda Labial/cirurgia , Fissura Palatina/cirurgia , Feminino , Humanos , Lactente , Masculino , Período Pré-Operatório , Estudos Retrospectivos
19.
Eur J Clin Pharmacol ; 78(3): 393-403, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35059757

RESUMO

BACKGROUND: This cross-sectional research was undertaken to determine the serum levels of asprosin, a novel white adipose tissue-derived glucogenic adipokine, in epileptic patients on valproic acid treatment. METHODS: Sixty-six patients diagnosed with idiopathic tonic-clonic generalized epilepsy were divided into three groups: those treated with valproic acid (n = 22), those treated with lamotrigine (n = 22), and twenty-two newly diagnosed or untreated patients. A control group was twenty-two, healthy volunteers with a similar distribution of gender and age. Body mass index (BMI) and fasting serum levels of asprosin, glucose, glycohemoglobin (HbA1c), insulin, and lipid profile were measured for both patients and control groups. Additionally, homeostasis model assessment for insulin resistance (HOMA-IR) was also calculated for the investigated groups. RESULTS: The mean BMI values and fasting serum levels of glucose, HbA1c, insulin, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglyceride were much higher in subjects treated with valproic acid than those in the other study groups. Furthermore, a higher number of participants in the valproic acid group fulfilled the insulin resistance criterion (defined as HOMA-IR > 2.5) compared with those in other study groups. The mean fasting serum asprosin concentration was also significantly higher in the valproic acid group than in other study groups. This was while the values of the study parameters were comparable in the healthy, un-treated, and lamotrigine groups. CONCLUSIONS: Our finding suggested that elevated asprosin level might be one of the pathological mechanisms involved in the development of obesity, insulin resistance, and metabolic disturbances related to valproic acid treatment.


Assuntos
Anticonvulsivantes/farmacologia , Epilepsia Tônico-Clônica/tratamento farmacológico , Fibrilina-1/efeitos dos fármacos , Lamotrigina/farmacologia , Ácido Valproico/farmacologia , Adulto , Anticonvulsivantes/uso terapêutico , Glicemia , Índice de Massa Corporal , Pesos e Medidas Corporais , Estudos Transversais , Feminino , Hemoglobina A Glicada , Humanos , Insulina/sangue , Lamotrigina/uso terapêutico , Lipídeos/sangue , Masculino , Ácido Valproico/uso terapêutico
20.
Gene ; 819: 146220, 2022 Apr 20.
Artigo em Inglês | MEDLINE | ID: mdl-35093446

RESUMO

The SMAD1 and SMAD5 genes belong to mothers against decapentaplegic proteins family, which participate in the BMP pathway to control skeletal myogenesis and growth. In the present study, we analyzed the associations between polymorphisms of SMAD1 and SMAD5 genes promoter and important economical traits in Qinchuan cattle. Four SNPs in the SMAD1 gene promoter and three SNPs in the SMAD5 promoter were identified by sequencing of 448 Qinchuan cattles. Allelic and frequency analyses of these SNPs resulted in eight haplotypes both in the promoters of the two genes promoter and identified potential cis-regulatory transcription factor (TF) components. In addition, correlation analysis showed that cattle SMAD1 promoter activity of individuals with Hap4 (P < 0.01) was stronger than that of individuals with Hap2. while the transcriptional activity of individuals with Hap3 within SMAD5 gene promoter was significantly (P < 0.01) higher followed by H2. Uniformly, diplotypes H4-H6 of SMAD1 gene and H1-H3 of SMAD5 gene performed significant (P < 0.01) associations with body measurement and improved carcass quality traits. All these results have indicated that polymorphisms in SMAD1 and SMAD5 genes promoter could impact the transcriptional regulation and then affect muscle content in beef cattle. Moreover, both the SMAD1 and SMAD5 genes were expressed ubiquitously in 10 tissues and had higher expression in the longissimus thoracis tissue from 6-month-old and 12-month-old cattle than in cattle of other ages. We can conclude that SMAD1 and SMAD5 genes may play an important role in muscle growth and development, and the variants mapped within SMAD1 and SMAD5 genes can be utilized in molecular marker-assisted selection for cattle carcass quality and body measurement traits in breed improvement programs of Qinchuan cattle.


Assuntos
Bovinos/genética , Bovinos/metabolismo , Estudos de Associação Genética , Polimorfismo de Nucleotídeo Único , Regiões Promotoras Genéticas , Proteína Smad1/genética , Proteína Smad5/genética , Alelos , Animais , Tamanho Corporal/genética , Pesos e Medidas Corporais , Genótipo , Haplótipos , Proteína Smad1/metabolismo , Proteína Smad5/metabolismo
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...