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1.
Braz. j. biol ; 84: e248946, 2024. tab, mapas, ilus
Artigo em Inglês | LILACS-Express | LILACS, VETINDEX | ID: biblio-1364502

RESUMO

Environmental pollutants may often alter the genetic components of natural populations. In this study, heavy metals and genetic diversity in land snail (Achatina achatina) from three populations of south-western Nigeria were investigated, using the Atomic Absorption Spectrometry and DNA Sequencing technology respectively. Metal analysis revealed that the snails accumulated lead (Pb) and nickel (Ni) in high concentrations in two of the three states, while cadmium (Cd) was the least detected. Editing and alignment of the sequences of all snail accessions generated a range of 384bp to 419 bp. Analysis of Molecular Variance (AMOVA) in all 18 accessions was low at only 16%. The query coverage (QC) ranged between 96% and 100%, with 14 (77.8%) of the 18 accessions showing 100% identity. Pairwise comparison of the accessions studied also showed a high genetic similarity. The unweighted pair group method with arithmetic mean (UPGMA) generated two main clusters. Cluster I was unique and contain one sample (AaOy06) while the other cluster are very closely related and can be further sub-divided into sub-clusters. The similarity index of between the clusters is 0.5357. The close similarity among the accessions may be due to the geographical proximity of the three states. The uniqueness of accession AaOy06 in comparison to other accessions might be due to the negative influence of heavy metal, particularly lead. The determination of evolutionary relationships among snail populations may be useful towards the breeding efforts of the species in Nigeria.


Os poluentes ambientais podem frequentemente alterar os componentes genéticos das populações naturais. Neste estudo, metais pesados e diversidade genética em caramujos terrestres (Achatina achatina) de três populações do sudoeste da Nigéria foram investigados, usando a tecnologia de espectrometria de absorção atômica e sequenciamento de DNA, respectivamente. A análise dos metais revelou que os caramujos acumularam chumbo (Pb) e níquel (Ni) em altas concentrações em dois dos três estados, enquanto o cádmio (Cd) foi o menos detectado. A edição e o alinhamento das sequências de todos os acessos de caramujos geraram uma faixa de 384pb a 419pb. A análise de variância molecular (AMOVA) em todos os 18 acessos foi baixa em apenas 16%. A cobertura da consulta (QC) variou entre 96% e 100%, com 14 (77,8%) dos 18 acessos apresentando 100% de identidade. A comparação pareada dos acessos estudados também mostrou alta similaridade genética. O método de grupo de pares não ponderados com média aritmética (UPGMA) gerou dois clusters principais. O cluster I era único e contém uma amostra (AaOy06), enquanto o outro cluster está intimamente relacionado e pode ser subdividido em subclusters. O índice de similaridade entre os clusters é 0,5357. A grande semelhança entre os acessos pode ser devido à proximidade geográfica dos três estados. A singularidade do acesso AaOy06 em comparação com outros acessos pode ser devido à influência negativa de metais pesados, particularmente chumbo. A determinação das relações evolutivas entre as populações de caramujos pode ser útil para os esforços de reprodução da espécie na Nigéria.


Assuntos
Animais , Caramujos , Variação Genética , Metais Pesados , Poluentes Ambientais
2.
Food Chem ; 399: 133970, 2023 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-35998499

RESUMO

Lateral flow immunoassays (LFIAs) are routine methods for rapid foodborne pollutants screening, with detection limits that are closely associated with the label probes used. The exploitation of high performance and robust probe is highly desirable, and remains a great challenge. Herein, we reported an emerging fluorescent nanobeads i.e. carbon-dots (CD) covalently incorporated mesoporous silicon nanoparticles (CD-MSNs) for LFIAs. CD-MSNs revealed brighter fluorescence, larger particle size and more modification sites in comparison with those of single CD. After bio-functionalisation, CD-MSNs probes were introduced to construct LFIA test strips, and designed for ultrasensitive detection of aflatoxin B1 (AFB1) and Staphylococcus aureus (S. aureus), two representative foodborne pollutants, based on the competitive and sandwich models, respectively. Very competitive quantitative detection limits i.e. 0.05 ng/mL and 102 cfu/mL were correspondingly obtained. Additionally, the test strips were successfully applied to rapidly and accurately screen AFB1 and S. aureus in food samples, highlighting their practicality.


Assuntos
Poluentes Ambientais , Nanopartículas , Aflatoxina B1/análise , Carbono , Corantes Fluorescentes , Imunoensaio/métodos , Limite de Detecção , Silício , Staphylococcus aureus
3.
Food Chem ; 399: 133958, 2023 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-36027812

RESUMO

The aim of study was to optimize an QuEChERS extraction procedure for simultaneous determination of organic pollutants in aquaculture products. The QuEChERS extracts were measured using LC-HRMS. The target contaminants include 32 pesticides and 20 pharmaceuticals which have not been regulated for the products in Korea. The method was validated according to CODEX guideline (CAC/GL 71-2009). LOD and LOQ for all analytes ranged from 0.1 to 2 µg/kg and from 0.5 to 5 µg/kg, respectively. Intra-day (n = 5) and inter-day (n = 9) accuracy and precision were evaluated with the guideline. The validated method was applied to aquaculture products (n = 303). As a result, 14 pesticides and 8 pharmaceuticals were quantified. Fluxapyroxad, a fungicide frequently detected in domestic surface waters, was found with relatively higher concentration in 17 out of 23 species. It proves that a hydrophobic inland contaminant can be accumulated in the aquaculture products.


Assuntos
Poluentes Ambientais , Resíduos de Praguicidas , Praguicidas , Aquicultura , Poluentes Ambientais/análise , Resíduos de Praguicidas/análise , Praguicidas/análise , Preparações Farmacêuticas/análise , Espectrometria de Massas em Tandem/métodos
4.
Braz. j. biol ; 83: e248910, 2023. tab, graf
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1339342

RESUMO

Abstract This study determines the associations among serum lipid profiles, risk of cardiovascular disease, and persistent organic pollutants. Using Gas chromatography technique, the intensity of toxic pollutant residues in serum samples of Hypertensive patients were measured. Based on statistical analysis, the effects of different covariates namely pesticides, age, systolic blood pressure, diastolic blood pressure, and lipid profile duration was checked using the logistic regression model. Statistical computation was performed on SPSS 22.0. The P-values of F-Statistic for each lipid profile class are greater than 0.01 (1%), therefore we cannot reject the null hypothesis for all cases. The estimated coefficients, their standard errors, Wald Statistic, and odds ratio of the binary logistic regression model for different lipid profile parameters indicate if pesticides increase then the logit value of different lipid profile parameters changes from -0.46 to -0.246 except LDL which increases by 0.135. The study reports a significantly increased threat of cardiovascular disease with increased concentrations of toxic pollutants.


Resumo Este estudo determina as associações entre o perfil lipídico sérico, o risco de doença cardiovascular e os poluentes orgânicos persistentes. Por meio da técnica de cromatografia gasosa, mediu-se a intensidade dos resíduos de poluentes tóxicos em amostras de soro de pacientes hipertensos. Com base na análise estatística, os efeitos de diferentes covariáveis ​​- ou seja, pesticidas, idade, pressão arterial sistólica, pressão arterial diastólica e duração do perfil lipídico - foram verificados usando o modelo de regressão logística. O cálculo estatístico foi realizado no SPSS 22.0. Os valores P da estatística F para cada classe de perfil lipídico são maiores que 0,01 (1%), portanto não podemos rejeitar a hipótese nula para todos os casos. Os coeficientes estimados, seus erros padrão, estatística de Wald e odds ratio do modelo de regressão logística binária para diferentes parâmetros do perfil lipídico indicam se os pesticidas aumentam, então o valor logit de diferentes parâmetros do perfil lipídico muda de -0,46 para -0,246, exceto LDL, que aumenta em 0,135. O estudo relata um aumento significativo da ameaça de doença cardiovascular com aumento das concentrações de poluentes tóxicos.


Assuntos
Humanos , Praguicidas , Poluentes Ambientais , Poluentes Orgânicos Persistentes , Lipídeos , Lipoproteínas
5.
Comput Math Methods Med ; 2022: 2152615, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36060653

RESUMO

Food is easy to be contaminated because of its complex composition. Therefore, in order to protect people from potential food contaminants, it is very necessary to test for various contaminants in food. Liquid chromatography is widely used in the field of food safety detection. In addition, with the development of liquid chromatography technology, more and more new instruments are combined with liquid chromatography. Compared with traditional liquid chromatography, combined liquid chromatography has great advantages in efficiency and operation. Therefore, it is rapidly promoted in the field of food safety testing. In this paper, the results of the determination of three kinds of food pollutants by different liquid chromatography methods are reviewed, and the indexes are compared and analyzed.


Assuntos
Poluentes Ambientais , Cromatografia Líquida , Humanos
6.
Eur J Dermatol ; 32(3): 305-311, 2022 05 01.
Artigo em Inglês | MEDLINE | ID: mdl-36065535

RESUMO

Short- and long-term exposure to atmospheric pollution has significant health effects. The skin is the organ directly in contact with pollutants and is responsible for protection of the organism. Particulate matter (PM) such as polycyclic aromatic hydrocarbons (PAHs) are the basis of certain pulmonary as well as dermatological complications. Pollution exacerbates certain illnesses such as atopic dermatitis and cancer, and it may also participate in delaying wound healing and in the occurrence of chronic ailments such as diabetes. The aryl hydrocarbon receptor (AhR) transcription factor, at the core of these responses to pollutants, is expressed by all cells of the skin. The AhR is subject to tight regulation that depends on its ligand. Pollutants act in a deleterious manner via the AhR, influencing the behaviour of keratinocytes as well as fibroblasts. Natural ligands, on the other hand, allow the noxious effects of pollution to be countered. This non-systematic review of the literature shows that modulation of AhR appears to be an excellent therapeutic approach to improve or stop the cutaneous problems linked to pollution.


Assuntos
Dermatite Atópica , Poluentes Ambientais , Receptores de Hidrocarboneto Arílico , Fatores de Transcrição Hélice-Alça-Hélice Básicos , Dermatite Atópica/metabolismo , Poluentes Ambientais/toxicidade , Humanos , Queratinócitos/efeitos dos fármacos , Queratinócitos/metabolismo , Receptores de Hidrocarboneto Arílico/fisiologia , Pele/efeitos dos fármacos , Pele/metabolismo
7.
Environ Health ; 21(1): 81, 2022 Sep 06.
Artigo em Inglês | MEDLINE | ID: mdl-36068579

RESUMO

RATIONALE: Studies examining the association of short-term air pollution exposure and daily deaths have typically been limited to cities and used citywide average exposures, with few using causal models. OBJECTIVES: To estimate the associations between short-term exposures to fine particulate matter (PM2.5), ozone (O3), and nitrogen dioxide (NO2) and all-cause and cause-specific mortality in multiple US states using census tract or address exposure and including rural areas, using a double negative control analysis. METHODS: We conducted a time-stratified case-crossover study examining the entire population of seven US states from 2000-2015, with over 3 million non-accidental deaths. Daily predictions of PM2.5, O3, and NO2 at 1x1 km grid cells were linked to mortality based on census track or residential address. For each pollutant, we used conditional logistic regression to quantify the association between exposure and the relative risk of mortality conditioning on meteorological variables, other pollutants, and using double negative controls. RESULTS: A 10 µg/m3 increase in PM2.5 exposure at the moving average of lag 0-2 day was significantly associated with a 0.67% (95%CI: 0.34-1.01%) increase in all-cause mortality. 10 ppb increases in NO2 or O3 exposure at lag 0-2 day were marginally associated with and 0.19% (95%CI: -0.01-0.38%) and 0.20 (95% CI-0.01, 0.40), respectively. The adverse effects of PM2.5 persisted when pollution levels were restricted to below the current global air pollution standards. Negative control models indicated little likelihood of omitted confounders for PM2.5, and mixed results for the gases. PM2.5 was also significantly associated with respiratory mortality and cardiovascular mortality. CONCLUSIONS: Short-term exposure to PM2.5 and possibly O3 and NO2 are associated with increased risks for all-cause mortality. Our findings delivered evidence that risks of death persisted at levels below currently permissible.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Poluentes Ambientais , Ozônio , Poluentes Atmosféricos/análise , Poluição do Ar/efeitos adversos , Poluição do Ar/análise , Estudos Cross-Over , Exposição Ambiental/efeitos adversos , Exposição Ambiental/análise , Poluentes Ambientais/análise , Humanos , Modelos Logísticos , Dióxido de Nitrogênio/efeitos adversos , Dióxido de Nitrogênio/análise , Ozônio/análise , Material Particulado/análise
8.
J Environ Manage ; 320: 115871, 2022 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-36056490

RESUMO

In this study, we i) assessed the occurrence of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in sediments, pore water, and bulk water from three different areas in Lake Neusiedl, Austria, and ii) investigated mechanisms regulating adsorption and remobilization of these substances under different conditions via multiple lab-scale experiments. The adsorption capacity was mainly influenced by sediments' organic matter content, oxide composition, and pre-loading. Results suggest that a further increase of PFAS-concentrations in the open lake can be partly buffered by sediment transport to the littoral zone and adsorption to sediments in the extended reed belt. But, under current conditions, the conducted experiments revealed a real risk for mobilization of PFOS and PFOA from reed belt sediments that may lead to their transport back into the lake. The amount of desorbed PFAS is primarily dependent on water/sediment- or pore water/water-ratios and the concentration gradient. In contrast, water matrix characteristics and oxygen levels played a minor role in partitioning. The highest risk for remobilizing PFOS and PFOA was observed in experiments with sediments taken near the only major tributary to the lake (river Wulka), which had the highest pre-loading. The following management advice for water transport between high and low polluted areas can be derived based on the results. First, to reduce emissions into Lake waters from polluted tributaries like the Wulka river, we recommend diffuse pathways through the reed belt in the lake's littoral to reduce pollutant transport into the Lake and avoid high local sediment loadings. Second, water exchange with dried-up areas with probable higher loadings should be carefully handled and monitored to avoid critical back transport in the open lake. And third, general work in the reed belt or generally in the reed should be accompanied by monitoring to prevent uncontrolled remobilization in the future.


Assuntos
Ácidos Alcanossulfônicos , Poluentes Ambientais , Fluorcarbonetos , Poluentes Químicos da Água , Adsorção , Caprilatos , Monitoramento Ambiental/métodos , Fluorcarbonetos/análise , Sedimentos Geológicos , Lagos , Água , Poluentes Químicos da Água/análise
9.
Nihon Yakurigaku Zasshi ; 157(5): 352-355, 2022.
Artigo em Japonês | MEDLINE | ID: mdl-36047152

RESUMO

The epidermal growth factor receptor (EGFR) is the most extensively examined receptor tyrosine kinase. Several EGFR mutations and modifications have been shown to induce self-activation, which plays a central role in carcinogenesis. Recently, environmental chemicals such as PM2.5 can also activate EGFR and become risk factors for cancer. Although, the detailed mechanism remains unknown. In this study, we focused on 1,2-naphthoquinone (1,2-NQ) which is a secondary metabolite of naphthalene. Humans are exposed to 1,2-NQ through the combustion of fossil and diesel fuel and from tobacco smoke and PM2.5. Here, we demonstrate that 1,2-NQ is a novel EGFR-specific activator. We found that 1,2-NQ forms a covalent bond called N-arylation with EGFR Lys80 which is in the extracellular domain by LC-MS/MS. This modification activates the EGFR-Akt signaling pathway, which inhibits serum deprivation-induced apoptosis in A549 cells. Our study reveals an original mode of EGFR activation via covalent binding. We propose the correlation between EGFR activation without ligands and environmental pollutant-associated diseases such as cancer.


Assuntos
Poluentes Ambientais , Cromatografia Líquida , Poluentes Ambientais/toxicidade , Receptores ErbB/genética , Receptores ErbB/metabolismo , Humanos , Naftoquinonas , Material Particulado , Fosforilação , Transdução de Sinais , Espectrometria de Massas em Tandem
10.
Wei Sheng Yan Jiu ; 51(4): 610-616, 2022 Jul.
Artigo em Chinês | MEDLINE | ID: mdl-36047267

RESUMO

OBJECTIVE: To measure polychlorinated biphenyls(PCBs) concentrations in serum of some reproductive aged men in Wuhan and explore the influencing factors of PCBs exposure. METHODS: Based on a cross-sectional study in 2013 on the association between exposure to environmental pollutants and adverse male reproductive health, which was conducted in Wuhan. Levels of dioxins-like PCBs(dl-PCBs) and non-dioxin-like PCBs(ndl-PCBs) in 101 serum samples of men with childbearing age were analyzed via high-resolution gas chromatograph tandem high-resolution mass spectrometer(HRGC-HRMS) method. Multiple linear regression models were used to analyze the associations between PCBs levels and influencing factors. RESULTS: Total concentrations of twelve dl-PCBs(Σdl-PCBs) were in range of 177.85-7271.48 pg/g lipid, the median value was 1530.71 pg/g lipid, and CB-118 was the predominant congener. For six ndl-PCBs, total concentrations(Σndl-PCBs) were in range of 1463.23-40561.47 pg/g lipid, the median value was 5498.37 pg/g lipid, and CB-153 was the predominant congener. The World Health Organization toxicity equivalent(WHO_(2005)-TEQ) of dl-PCBs(ΣTEQ_(dl-PCBs)) were 0.02-162.29 pg TEQ/g lipid, the median value was 1.77 pg TEQ/g lipid. The age was positively correlated with Σmono-ortho PCBs(ß=0.01, 95%CI 0.00-0.02), ΣTEQ_(mono-ortho PCBs)(ß=0.01, 95%CI 0.00-0.02) and Σndl-PCBs(ß=0.02, 95%CI 0.00-0.03). Men who drank alcohol tend to show higher exposure to ΣTEQ_(dl-PCBs)(ß=0.56, 95%CI 0.13-1.00) than those did not drink alcohol. And higher levels of Σndl-PCBs(ß=0.15, 95%CI 0.04-0.26) was found in the men who reside in urban areas as compared to rural one. CONCLUSION: There were PCBs exposure in some reproductive aged men in Wuhan. Age, drink alcohol status, and residence were influencing factors on PCBs.


Assuntos
Benzofuranos , Dioxinas , Poluentes Ambientais , Bifenilos Policlorados , Dibenzodioxinas Policloradas , Adulto , Benzofuranos/análise , Estudos Transversais , Dibenzofuranos Policlorados , Dioxinas/análise , Poluentes Ambientais/análise , Humanos , Lipídeos , Masculino , Bifenilos Policlorados/análise , Dibenzodioxinas Policloradas/análise
14.
J Environ Public Health ; 2022: 3792356, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36120158

RESUMO

In recent years, the economy of enterprises has developed rapidly. Most enterprises focus on economic interests and ignore the occupational health of employees, resulting in an increase in the occupational morbidity rate of employees. Occupational insecurity of corporate employees will reduce the work efficiency of employees. In turn, it will affect the economic development of the enterprise. Paying attention to the occupational health and safety development of corporate employees is a necessary measure for corporate economic development. The main reasons that endanger the occupational health of employees are the unreasonable discharge of pollutants and the substandard treatment of pollutants. The sustainable environmental strategy of enterprise development can well control the risk factors that endanger the occupation of enterprise employees, and it is conducive to the health and safety development of enterprise employees and enterprises. This paper studied the impact of sustainable environmental factors on the occupational health and safety development of enterprise employees through the fuzzy analytic hierarchy process and analyzed the impact on the occupation of enterprise employees according to the larger influencing factors. The experimental results showed that heavy metal wastewater, dust, hydrogen sulfide gas, and high-temperature radiation are the four most weighted impact indicators. Different concentrations of these four indicators are tested; when the concentration value of these impact indicators is low, it has little impact on the occupational safety and development of enterprise employees. However, when the concentration increases, the occupational safety and development of enterprise employees are seriously reduced. When the safety is the lowest, it is only 20%, and the development is only 23%. Carrying out sustainable environmental development can reduce the discharge of industrial waste; hence, while protecting the environment, the occupational health and safety and development potential of employees can be improved.


Assuntos
Poluentes Ambientais , Sulfeto de Hidrogênio , Saúde do Trabalhador , Poeira , Humanos , Resíduos Industriais , Gestão da Segurança , Águas Residuárias
15.
Chempluschem ; 87(9): e202200182, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-36100557

RESUMO

Urban gardening is becoming increasingly popular. Air pollution, which is a major concern in cities might, however, threaten food safety and thus must be assessed. Health risks arise particularly from toxic persistent organic pollutants such as Polycyclic Aromatic Hydrocarbons (PAHs) which are formed by incomplete combustion. A first assessment of crop contamination in two different atmospheric environments in the urban area of Nice reveals a predominance of light PAHs. These pollutants present in the gaseous phase, seem to bioaccumulate while heavy PAHs are absent in vegetation. By understanding the PAH sources and their behavior in the atmosphere but also by analyzing the spatial and temporal data since the European directive in 2004, a link between concentrations found in vegetables grown in experimental gardens and PAH cadastral emission data is presented. The first results could be used as a possible guidance for urban agriculture.


Assuntos
Poluentes Atmosféricos , Poluentes Ambientais , Hidrocarbonetos Policíclicos Aromáticos , Poluentes Atmosféricos/análise , Transporte Biológico , Monitoramento Ambiental/métodos , Hidrocarbonetos Policíclicos Aromáticos/análise
16.
World J Microbiol Biotechnol ; 38(12): 222, 2022 Sep 14.
Artigo em Inglês | MEDLINE | ID: mdl-36100774

RESUMO

Intestinal peristalsis is essential for gastrointestinal function, which could maintain the appropriate progression and digestion of food and reduce bacterial aggregation through mixing function. Even though certain ingredients of foodstuff are known to increase or decrease intestinal peristalsis, the role of environmental pollutants on intestinal peristalsis is relatively unknown. Therefore, the effects of four typical environmental pollutants (oxytetracycline, arsenic, polychlorinated biphenyls and chlorpyrifos) on intestinal peristalsis in the zebrafish model and then tested the recovery effect of the constipation-resistant probiotic. The results showed that 4-day environmental pollutants exposures on the zebrafish embryos at 1 day post fertilization clearly decreased the intestinal peristalsis through decreasing the serotonin (5-HT) production and down-regulating the expression of key genes involved in 5-HT synthesis. Pollutants-evoked change of gut motility could be normalized in the presence of Lactobacillus rhamnosus GG (LGG) via increasing 5-HT secretion. Exogenous 5-hydroxytryptophan (100 µg/L) could also rescue the dysfunction of gut motility in pollutants-treated zebrfish. The data identified that LGG normalized disorder of intestinal peristalsis induced by environmental pollutants through increasing 5-HT level. The stimulant effect of LGG on peristalsis may be associated with 5-HT system, which could provide references for the application of probiotics in regulation of gut dysmotility.


Assuntos
Poluentes Ambientais , Lactobacillus rhamnosus , Animais , Poluentes Ambientais/metabolismo , Poluentes Ambientais/toxicidade , Lactobacillus rhamnosus/genética , Lactobacillus rhamnosus/metabolismo , Larva , Serotonina/metabolismo , Peixe-Zebra
17.
Ecotoxicol Environ Saf ; 241: 113837, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-36068761

RESUMO

Evidence of the influence of prenatal phthalate exposure on childhood longitudinal obesity markers is limited. Nested on the Ma'anshan birth cohort study, 990 mother-daughter pairs were included. Seven phthalate metabolites were determined in urine collected in each trimester. Each child underwent a physical examination from birth to 6 years of age twelve times. Latent class growth models were used to identify three trajectories of girls' body mass index (BMI). Logistic regression, quantile g-computation and Bayesian kernel machine regression models analyzed the relationships of prenatal exposure to individual and mixed phthalates with girls' body mass index (BMI) trajectory. Compared to the "lowest trajectory" class, prenatal average concentrations of mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP, ORcrude = 2.095, 95 % CI = 1.014-4.328) and di(2-ethylhexyl) phthalate (DEHP, ORcrude = 2.336, 95 % CI = 1.022-5.338) during pregnancy were associated with an increased probability of being in the "highest trajectory" class. The average concentration of DEHP (ORcrude = 1.879, 95 % CI = 1.002-3.522) was associated with an increased probability of being in the "moderate trajectory" class. Stratified analyses by trimester of pregnancy mainly showed that third-trimester exposure to monoethyl phthalate (MEP, ORadjusted = 1.584, 95 % CI = 1.094-2.292), mono(2-ethyl-5-oxohexyl) phthalate (MEOHP, ORadjusted = 2.885, 95 % CI = 1.367-6.088), MEHHP (ORadjusted = 2.425, 95 % CI = 1.335-4.407), DEHP (ORadjusted = 2.632, 95 % CI = 1.334-5.193) and high molecular weight phthalate (ORadjusted = 2.437, 95 % CI = 1.239-4.792) was associated with an increased probability of being in the "highest trajectory" class. However, the mixture of phthalates was not significantly related to the girl's BMI trajectory. In conclusion, in utero exposure to phthalates, including MEP and DEHP metabolites (MEHHP and MEOHP), was significantly associated with early childhood high BMI trajectories in girls. The third trimester of pregnancy seemed to be the window of vulnerability to phthalate exposure for girls' high BMI trajectory at periods of prenatal development. No evidence supported a significant relationship between combined exposure to phthalate metabolites and girls' high BMI trajectory.


Assuntos
Dietilexilftalato , Poluentes Ambientais , Ácidos Ftálicos , Teorema de Bayes , Índice de Massa Corporal , Criança , Pré-Escolar , Estudos de Coortes , Dietilexilftalato/toxicidade , Exposição Ambiental/análise , Poluentes Ambientais/análise , Feminino , Humanos , Lactente , Recém-Nascido , Ácidos Ftálicos/urina , Gravidez , Vitaminas
18.
Bioengineered ; 13(6): 14730-14748, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-36098071

RESUMO

The increased antibiotic consumption and their improper management led to serious antibiotic pollution and its exposure to the environment develops multidrug resistance in microbes against antibiotics. The entry rate of antibiotics to the environment is much higher than its exclusion; therefore, efficient removal is a high priority to reduce the harmful impact of antibiotics on human health and the environment. Recent developments in cost-effective and efficient biochar preparation are noticeable for their effective removal. Moreover, biochar engineering advancements enhanced biochar remediation performance several folds more than in its pristine forms. Biochar engineering provides several new interactions and bonding abilities with antibiotic pollutants to increase remediation efficiency. Especially heteroatoms-doping significantly increased catalysis of biochar. The main focus of this review is to underline the crucial role of biochar in the abatement of emerging antibiotic pollutants. A detailed analysis of both native and engineered biochar is provided in this article for antibiotic remediation. There has also been discussion of how biochar properties relate to feedstock, production conditions and manufacturing technologies, and engineering techniques. It is possible to produce biochar with different surface functionalities by varying the feedstock or by modifying the pristine biochar with different chemicals and preparing composites. Subsequently, the interaction of biochar with antibiotic pollutants was compared and reviewed. Depending on the surface functionalities of biochar, they offer different types of interactions e.g., π-π stacking, electrostatic, and H-bonding to adsorb on the biochar surface. This review demonstrates how biochar and related composites have optimized for maximum removal performance by regulating key parameters. Furthermore, future research directions and opportunities for biochar research are discussed.


Assuntos
Poluentes Ambientais , Adsorção , Antibacterianos , Carvão Vegetal/química , Humanos
19.
J Mol Model ; 28(10): 318, 2022 Sep 16.
Artigo em Inglês | MEDLINE | ID: mdl-36109369

RESUMO

Carbon nanotubes have several applications including the removal of pollutants via adsorption. Many studies were carried out in order to evaluate how the functionalization of these materials improves the efficiency of the process. However, a better understanding of the mechanisms involved in adsorption on nanotubes is still needed. In this work it was evaluated how the oxidation of nanotubes influences the adsorption of a model molecule (methylene blue). For this purpose, a realistic model described on the grand canonical ensemble was used. In this approach, the experimental isotherms were adjusted and provided relevant information about the process, such as the number of layers and the orientation of the adsorbed molecules. In addition, since the treatment is based on statistical mechanics, it was possible to calculate the configurational entropy and Gibbs free energy of the process.


Assuntos
Poluentes Ambientais , Nanotubos de Carbono , Adsorção , Azul de Metileno
20.
Sci Rep ; 12(1): 15499, 2022 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-36109538

RESUMO

The jeopardy of the synthetic dyes effluents on human health and the environment has swiftly aggravated, threatening human survival. Hence, sustained studies have figured out the most acceptable way to eliminate this poisonous contaminant. Thereby, our investigation aimed to fabricate montmorillonite/magnetic NiFe2O4@amine-functionalized chitosan (MMT-mAmCs) composite as a promising green adsorbent to remove the cationic methylene blue (MB) and crystal violet (CV) dyes from the wastewater in neutral conditions. Interestingly, MMT-mAmCs composite carries high negative charges at a wide pH range from 4 to 11 as clarified from zeta potential measurements, asserting its suitability to adsorb the cationic contaminants. In addition, the experimental study confirmed that the optimum pH to adsorb both MB and CV was pH 7, inferring the ability of MMT-mAmCs to adsorb both cationic dyes in simple process conditions. Furthermore, the ferromagnetic behavior of the MMT-mAmCs composite is additional merit to our adsorbent that provides facile, fast, and flawless separation. Notably, the as-fabricated composite revealed an auspicious adsorbability towards the adsorptive removal of MB and CV, since the maximum adsorption capacity of MB and CV were 137 and 118 mg/g, respectively. Moreover, the isotherm and kinetic investigatins depicted that the adsorption of both cationic dyes fitted Langmuir and Pseudo 2nd order models, respectively. Besides, the advanced adsorbent preserved satisfactory adsorption characteristics with maximal removal efficacy exceeding 87% after reuse for ten consecutive cycles. More importantly, MMT-mAmCs efficiently adsorbed MB and CV from real agricultural water, Nile river water and wastewater samples at the neutral pH medium, reflecting its potentiality to be a superb reusable candidate for adsorptive removal cationic pollutants from their aquatic media.


Assuntos
Quitosana , Poluentes Ambientais , Purificação da Água , Aminas , Bentonita/química , Cátions , Corantes/química , Violeta Genciana , Humanos , Azul de Metileno/química , Compostos Organometálicos , Águas Residuárias/química , Água
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