Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 31.335
Filtrar
1.
Psychiatr Danub ; 31(3): 355-357, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31596829

RESUMO

We aimed to compare processing speed (PS) and its subcomponents in schizophrenia (SC) and schizoaffective disorder (SA). Thirty-five patients were divided into two groups (SC=18; SA=17). PS tasks from the MATRICS Consensus Cognitive Battery Central/South America version were used. Additional PS subcomponents were analyzed (i.e., behavioral execution, response processing, and accuracy). SA obtained significant higher scores than SC in response processing, verbal fluency and the PS general domain. Our results indicate that PS is a potential cognitive marker to differentiate between SC and SA. Further research with larger samples must be conducted.


Assuntos
Transtornos Cognitivos/fisiopatologia , Transtornos Cognitivos/psicologia , Transtornos Psicóticos/fisiopatologia , Transtornos Psicóticos/psicologia , Esquizofrenia/fisiopatologia , Psicologia do Esquizofrênico , Transtornos Cognitivos/complicações , Humanos , Testes Neuropsicológicos , Projetos Piloto , Transtornos Psicóticos/complicações , Esquizofrenia/complicações
2.
Psychiatr Hung ; 34(3): 287-299, 2019.
Artigo em Húngaro | MEDLINE | ID: mdl-31570660

RESUMO

Rapid development in information technology has been observed recently and has led to valuable developments also in healthcare. 3D-bio-printing or the virtual simulations that help the acquisition of anatomical and pathological knowledge and testing the acquired knowledge are just some of the examples. This progress can be recognized also in psychiatry. One of the most spectacular ways of using these technologies in psychiatry might be the therapeutic techniques associated with Virtual Reality (VR) simulations, which are currently available for anxiety disorders, eating disorders and addictions. A research team of the Psychiatric and Psychotherapeutic Department of the Semmelweis University has developed a Virtual Reality-based intervention that fits in with this perspective. The intervention mainly aims at Theory of Mind deficit and pragmatic language impairment in schizophrenia. In this article the current status of our research team's work will be presented. The article reviews the literature that provides the basis for the development, leads the reader through the main stages of the development process, and finally the program itself will be introduced. Process and mechanism of change associated with the intervention and the potential risks of the use of VR will also be discussed.


Assuntos
Esquizofrenia/terapia , Psicologia do Esquizofrênico , Teoria da Mente , Realidade Virtual , Humanos , Psiquiatria/métodos
3.
Psychiatr Danub ; 31(Suppl 3): 261-264, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31488738

RESUMO

BACKGROUND: Schizophrenia can be interpreted as a pathology involving the neocortex whose cognitive dysfunctions represent a central and persistent characteristic of the disease, as well as one of the more important symptoms in relation to the impairment of psychosocial functioning and the resulting disabilities. Given the implication of cognitive functions in everyday life, they can better predict the degree of schizophrenia. The study proposes to use Machine Learning techniques to identify the specific cognitive deficits of schizophrenia that mostly characterize the disorder, as well as to develop a predictive system that can diagnose the presence of schizophrenia based on neurocognitive tests. BACKGROUND: The study employs a dataset of neurocognitive assessments carried out on 201 people (86 schizophrenic patients and 115 healthy patients) recruited by the Neuroscience Group of the University of Bari "A. Moro". A data analysis process has been carried out, with the aim of selecting the most relevant features as well as to prepare data for training a number of "off-the-shelf" machine learning methods (Decision Tree, Random Forest, Logistic Regression, k-Nearest Neighbor, Neural Network, Support Vector Machine), which have been evaluated in terms of classification accuracy according to stratified 20-fold cross-validation. RESULTS: Among all variables, 14 were selected as the most influential for the classification problem. The variables with greater influence are related to working memory, executive functions, attention, verbal fluency, memory. The best algorithms turned out to be Support Vector Machine (SVM) and Neural Network, showing an accuracy of 87.8% and 84.8% on a test set. CONCLUSIONS: Machine Learning provides "cheap" and non-invasive methods that potentially enable early intervention with specific rehabilitation interventions. The results suggest the need to integrate a thorough neuropsychological evaluation into the more general diagnostic evaluation of patients with schizophrenia disorder.


Assuntos
Transtornos Cognitivos/complicações , Transtornos Cognitivos/diagnóstico , Disfunção Cognitiva/complicações , Disfunção Cognitiva/diagnóstico , Aprendizado de Máquina , Esquizofrenia/complicações , Esquizofrenia/diagnóstico , Cognição , Humanos , Testes Neuropsicológicos , Psicologia do Esquizofrênico
4.
Psychiatr Danub ; 31(Suppl 3): 517-519, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31488783

RESUMO

BACKGROUND: In the literature we can find evidence that sex hormones are involved the alterations of cognition in schizophrenic patients. Another factor, which may have an impact on cognitive domains in this clinical group inflammatory processes. The objective of this review was to explore studies, in which the role of both immunological factors and sex hormones on cognitive functions in schizophrenia are analyzed. METHODS: The search of papers covering this topic in PubMed and Google Scholar was performed. RESULTS: Endocrine factors like: testosteron, estrogen, as well as immunomodulatory are observed to play a role in cognitive functioning in schizophrenia. CONCLUSIONS: More studies are necessary to confirm these possible co-relations.


Assuntos
Transtornos Cognitivos , Cognição , Hormônios Esteroides Gonadais , Inflamação , Esquizofrenia , Psicologia do Esquizofrênico , Transtornos Cognitivos/complicações , Transtornos Cognitivos/metabolismo , Transtornos Cognitivos/patologia , Hormônios Esteroides Gonadais/metabolismo , Humanos , Inflamação/metabolismo , Esquizofrenia/complicações , Esquizofrenia/metabolismo , Esquizofrenia/patologia
5.
Psychiatr Danub ; 31(Suppl 3): 524-529, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31488785

RESUMO

BACKGROUND: Environment and culture are shown to be an important factor influencing characteristics of psychotic symptoms. Content of hallucinations and delusions is a projection of internal processes on external world. Religion plays a central role to lives of many people, but in schizophrenia religious experience and spirituality is confounded by psychotic symptoms. The aim of this study was to find how content of hallucinations and delusions interact with cultural conditions, that were changing over the decades. SUBJECTS AND METHODS: 100 of case histories from 2012 were randomly selected. From the medical record, content of hallucinations and delusion was extracted and categorized. Data from 2012 was compared with previous study by the authors, obtaining perspective of 80 years of history in the one hospital. RESULTS: Religious content of delusions and hallucinations appeared in 26% of patients. Diversity of the religious and spiritual themes in schizophrenia has been gradually decreasing. Many minor religious entities and figures such as "saints" and "angels" disappeared in 2012. Although, occurrence of contact with God and other religious figures was similar as in previous years, number of "visions" abruptly decreased. All of the religious content was culture-specific. CONCLUSIONS: Religious topics express general plasticity over a time, following cultural changes in society.


Assuntos
Evolução Cultural , Delusões/psicologia , Alucinações/psicologia , Religião e Psicologia , Esquizofrenia/complicações , Psicologia do Esquizofrênico , Delusões/complicações , Alucinações/complicações , Humanos
6.
Psychiatr Danub ; 31(Suppl 3): 543-548, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31488788

RESUMO

BACKGROUND: The attitudes of schizophrenic patients toward medications directly impact the treatment compliance. Although noncompliance represents a serious concern in long-term schizophrenia treatment, a detailed information on the factors that impair compliance is still limited. The present study aims to assess the factors related to noncompliance with antipsychotics agents, in long-term treated chronic paranoid schizophrenia patients. SUBJECTS AND METHODS: Two groups of such patients (total number n=162) were analyzed and compared: 1). patients with symptomatic remission on haloperidol (n=32), clozapine (n=40) or olanzapine (n=45), and 2). drug resistant patients (n=45). The mean duration of the disease was 19.3 years. RESULTS: Altogether, in our patient sample, a better drug attitude was found in the olanzapine and clozapine groups. Our findings have also revealed that worse attitude toward antipsychotics correlated with an earlier onset of schizophrenia, younger patient age, shorter duration of the disease, higher burden of symptoms, treatment with a typical antipsychotics, and higher severity of akathisia. CONCLUSION: Our results suggest that detecting factors that influence the patient's attitude toward medications might be helpful for designing targeted educational strategies in chronic schizophrenia patients (particularly those with the high risk of noncompliance), and further trials are warranted to explore this topic.


Assuntos
Antipsicóticos/administração & dosagem , Antipsicóticos/uso terapêutico , Cooperação do Paciente , Esquizofrenia/tratamento farmacológico , Psicologia do Esquizofrênico , Clozapina/administração & dosagem , Clozapina/uso terapêutico , Haloperidol/administração & dosagem , Haloperidol/uso terapêutico , Humanos , Olanzapina/administração & dosagem , Olanzapina/uso terapêutico , Cooperação do Paciente/psicologia , Cooperação do Paciente/estatística & dados numéricos , Fatores de Risco
7.
Hu Li Za Zhi ; 66(5): 20-25, 2019 Oct.
Artigo em Chinês | MEDLINE | ID: mdl-31549377

RESUMO

Schizophrenia is a basic self-disturbance that in its early stages causes the sufferer discomfort toward feelings of self. Therefore, fragility or abnormality with regard to sense of self was a core observation of early schizophrenia theory. Rather than body-image-related depression or anorexia, disturbed body experience is the main factor affecting body image in patients with schizophrenia. This is a concept that has been discussed in the literature in recent years. This article will introduce the body self model, discuss the schizophrenic symptoms that influence experienced body disturbances and reduce body self-functions, and explore the relationship between body identity and body image. In order to improve the body image of patients with schizophrenia, it is necessary to conduct assessments and interventions that enhance the sense of body identity.


Assuntos
Imagem Corporal/psicologia , Esquizofrenia/enfermagem , Psicologia do Esquizofrênico , Humanos
8.
Artigo em Russo | MEDLINE | ID: mdl-31464284

RESUMO

AIM: To establish an effect of alcohol dependence on the cognitive functions of patients with schizophrenia. MATERIAL AND METHODS: One hundred patients with paranoid schizophrenia were examined. Half of them had a co-occurring diagnosis of alcohol dependence syndrome. Memory, attention, thinking were studied. Comparisons were made between groups, depending on the presence of the addictive disorder. RESULTS: Attention and short-term memory are at the low border of normal values in both groups. No significant between-group differences were found. In Benton test, errors characteristic of schizophrenia were more frequent in the main group. 'Organic' errors were prevalent in the control group. Mild thinking disorders of organic type were significantly more frequent in the main group. CONCLUSION: Co-occurring alcohol dependence does not significantly influence intelligence but significant organic stigmas contribute to the structure of the cognitive profile of patients. The prevalence of organic disturbances in the structure of thinking in patients with co-occurring alcohol abuse was revealed. The best indicators of attention were demonstrated by patients with attack-like schizophrenia without substance abuse. This suggests that the influence of the alcohol factor differs in continuous and attack-like progressive schizophrenia.


Assuntos
Alcoolismo , Transtornos Cognitivos , Psicologia do Esquizofrênico , Alcoolismo/psicologia , Cognição , Transtornos Cognitivos/complicações , Comorbidade , Humanos , Memória de Curto Prazo
10.
Artigo em Russo | MEDLINE | ID: mdl-31317883

RESUMO

At the modern level of knowledge, classification of asthenic deficit as an independent psychopathological category and, in general terms, as the classification of asthenic symptomatic complexes of negative symptoms within schizophrenia and schizophrenia spectrum disorders is the subject of discussion. Studies of recent decades have shown that asthenia cannot be considered as a separate deficient monosyndrome, does not fit into the framework of negative disorders and is excluded from the block of scales of negative symptoms (SANS, PANSS, BNSS, CAINS). The authors suggest a working hypothesis that asthenia symptomatic complexes within schizophrenia are not comparable either in nature or in their psychopathological structure with primary deficiency disorders determined by the disease process. However, at the same time schizoasthenia, acting as a manifestation of the coenesthesiopathic hypochondriacal register, i.e. essentially in the space of positive disorders, is formed in close dependence on negative symptoms and is thus one of the markers of the already formed defect.


Assuntos
Esquizofrenia , Psicologia do Esquizofrênico , Astenia , Biomarcadores , Humanos , Escalas de Graduação Psiquiátrica , Psicopatologia
11.
Nord J Psychiatry ; 73(6): 317-322, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31215824

RESUMO

Background: Understanding the etiology of violence in patients with schizophrenia is an issue of great clinical and public importance. Although personality traits are an important aspect in determining complex behaviors of schizophrenia patients, there is a lack of research on the relationship between personality traits and violence, especially homicidal behavior, in this population. Aim: We aimed to compare temperament and character dimensions between homicidal and other mostly violent forensic patients with schizophrenia, and to determine which temperament and character dimensions are associated with homicidal behavior in these patients. Methods: We recruited 71 male forensic schizophrenia patients without concomitant substance dependence and antisocial personality disorder. The patients were divided into two groups according to trial documentation as: (1) Homicide and attempted homicide group (N 30; 42%), and (2) Other offenses group (N 41; 58%). Patients were assessed by means of the Temperament and Character Inventory and the Positive and Negative Syndrome Scale. Differences between groups were tested with t-test. Results: The two groups of patients were similar in their PANSS scores, but the homicidal men were significantly more likely to show higher harm avoidance (HA) scores than the less violent comparison men (t = 2,876, df-69, p = 0.005). Conclusions: Our results indicate that forensic schizophrenic patients with higher HA scores would show a greater risk of homicidal violence. Improved understanding of personality traits associated with such behavior is needed in order to prevent homicidal behavior. Importance of these results suggests that further study is needed.


Assuntos
Caráter , Homicídio/psicologia , Esquizofrenia , Psicologia do Esquizofrênico , Temperamento , Adulto , Agressão , Criminosos/psicologia , Redução do Dano , Humanos , Masculino , Inventário de Personalidade , Violência
12.
Psychopharmacology (Berl) ; 236(5): 1471-1489, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-31197432

RESUMO

Schizophrenia and autism spectrum disorder have long been associated with elevated levels of various small phenolic molecules (SPMs). In turn, the gut microbiota (GMB) has been implicated in the kinetics of many of these analytes. Unfortunately, research into the possible relevance of GMB-mediated SPMs to neuropsychiatry continues to be limited by heterogeneous study design, numerous sources of variance and technical challenges. Some SPMs have multiple structural isomers and most have conjugates. Without specialized approaches, SPMs can be incorrectly assigned or inaccurately quantified. In addition, SPM levels can be affected by dietary polyphenol or protein consumption and by various medications and diseases. Nonetheless, heterotypical excretion of various SPMs in association with schizophrenia or autism continues to be reported in independent samples. Recent studies in human cerebrospinal fluid demonstrate the presence of many SPMs A large number of these are bioactive in experimental models. Whether such mechanisms are relevant to the human brain in health or disease is not known. Systematic metabolomic and microbiome studies of well-characterized populations, an appreciation of multiple confounds, and implementation of standardized approaches across platforms and sites are needed to delineate the potential utility of the phenolic interactome in neuropsychiatry.


Assuntos
Transtorno do Espectro Autista/metabolismo , Encéfalo/metabolismo , Microbioma Gastrointestinal/fisiologia , Fenóis/metabolismo , Esquizofrenia/metabolismo , Transtorno do Espectro Autista/psicologia , Encéfalo/efeitos dos fármacos , Microbioma Gastrointestinal/efeitos dos fármacos , Humanos , Polifenóis/administração & dosagem , Polifenóis/metabolismo , Psicologia do Esquizofrênico
13.
Georgian Med News ; (289): 120-126, 2019 Apr.
Artigo em Russo | MEDLINE | ID: mdl-31215892

RESUMO

The aim of the study was to determine the level of intelligence in people with schizophrenia from childhood and adolescence. It is noteworthy that such studies were not conducted in Georgia. A total of 250 schizophrenic patients under the age of 45 who had the disease started before the age of 18 and who were treated in a psychiatric institution were examined. The study analyzed the obtained data on the level of intelligence from the point of view of age, sex, age of onset of the disease and its type, diagnosis and education. As a result of the study, it was found that a high premorbidal intellectual level contributes to combating the symptoms of the disease, high motivation, less resistance to the conducted drug and other treatment methods, the desire to cooperate with specialists, which helps maintain the level of functioning, including the desire to get an education. No correlation was discovered between the type of disease (negative or positive symptoms) and the IQ (intelligence quotient). To maintain the daily functioning of schizophrenic patients, it is very important to maintain intellectual abilities at the onset of the disease, for which, along with pharmacological treatment, it is necessary to provide cognitive exercises and psychosocial support.


Assuntos
Inteligência , Esquizofrenia , Psicologia do Esquizofrênico , Adolescente , Adulto , Criança , Humanos , Testes de Inteligência , Adulto Jovem
14.
Psychiatr Danub ; 31(Suppl 2): 143-147, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31158114

RESUMO

The perception of reward exerts a powerful influence on human behavior. While anhedonia might occur in healthy individuals, its prevalence and severity are much higher in psychiatric patients, particularly those with depression and schizophrenia. Anhedonia is a negative symptom, and presumably a trait marker in schizophrenia. Recent research confirmed that anhedonia is a complex construct, consisting of anticipatory, consummatory, and reward learning components. In general, schizophrenia patients show anticipation deficits, and a substantial portion of them have physical (PA) and social anhedonia (SA). The relationship between anhedonia and psychopathology appears bidirectional. While gene-environment interactions affect reward circuity, anhedonia modulates clinical features, such as suicidality and nicotine consumption. Future clinical research employing longitudinal designs may shed more light on the dynamics and treatment of anhedonia in schizophrenia.


Assuntos
Anedonia , Esquizofrenia , Depressão , Humanos , Recompensa , Psicologia do Esquizofrênico
15.
Psychiatr Danub ; 31(Suppl 2): 181-184, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31158119

RESUMO

This article reviews cognitive models of positive and negative symptoms of schizophrenia, as well as basic principles of cognitive behavioural therapy (CBT) for hallucinations, delusions and negative symptoms. Cognitive models of schizophrenia posit that individuals' view of the self is influenced by a combination of genetic vulnerability, early childhood experience and environmental stressors later in the life, and that these factors determine how internal and external experiences are interpreted. Cognitive behavioural therapy for schizophrenia is based on the basic principles of CBT and establishes connection between thoughts, emotions and behaviour. Treatment focuses on the meaning the individual attributes to psychotic experience, his or her understanding of it and ways of coping with symptoms, and is intended to reduce the distress caused by psychotic experience and correct thoughts and assumptions that are incompatible with objective evidence. The latest contradictory data on the efficacy of CBT for schizophrenia point to the need to use protocols that are tailored to specific symptoms and subgroups of patients based on the stage of illness, level of neurocognitive impairment and severity of the disorder, and manual-based in order to ensure fidelity of implementation.


Assuntos
Delusões , Alucinações , Esquizofrenia , Psicologia do Esquizofrênico , Cognição , Terapia Cognitivo-Comportamental , Feminino , Humanos , Esquizofrenia/complicações , Esquizofrenia/terapia
16.
J Forensic Leg Med ; 66: 8-24, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31176280

RESUMO

The present paper aims to describe a case of a schizophrenia spectrum disorder relapse leading to attempted murder, review literature, and investigate the epidemiological data and expression of violent behavior among Capgras-related incidents. 109 case reports deriving from various scientific areas dating from 1971 to 2017 were evaluated and juxtaposed with an equivalent comparison group of random psychiatry inpatients, who were examined for the same variables. Quantitative and qualitative differences were observed between samples. High level of interpersonal violence was disclosed among Capgras-related incidents, especially towards the main care-givers, with higher propensity among male patients. Homicidal behavior was also expressed in higher levels among male patients experiencing the Capgras delusion. A multidisciplinary approach is vital for the optimal management of these incidents. Further research on the pathophysiology of Capgras delusion with the utilization of functional imaging techniques is of exceptional significance for the understanding of issues of neuroscience.


Assuntos
Síndrome de Capgras/psicologia , Homicídio , Psicologia do Esquizofrênico , Adulto , Distribuição por Idade , Cuidadores , Psiquiatria Legal , Humanos , Masculino , Doenças Neurodegenerativas/complicações , Doenças Neurodegenerativas/psicologia , Neuroimagem , Distribuição por Sexo , Violência
17.
Saudi Med J ; 40(5): 475-482, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-31056625

RESUMO

OBJECTIVES: To investigate the relationship between suicide attempts and demographic-clinical variables and to assess the methods used in suicide attempts by comparing schizophrenia patients with and without suicide attempts. METHODS: A retrospective study with a total of 223 schizophrenia patients aged 18-65 years that were admitted to the Department of Psychiatry, Selcuk University and the Beyhekim Psychiatric Clinic Konya Training and Research Hospital, Konya, Turkey, between January 2014 and January 2018. The data collection forms created by researchers were completed using hospital medical records. Results: It was determined that 40.8% of schizophrenia patients attempted suicide at least once and that 39.6% of schizophrenia patients who attempted suicide had recurrent suicide attempts. Those with suicide attempts had a significantly longer mean duration of untreated psychosis and a higher total number of hospitalizations compared to those without suicide attempts. In addition, the use of depot antipsychotic drugs was significantly lower in those with suicide attempts. There was a statistically significant difference in the presence of traumatic life events between those with and without suicide attempts. Conclusion: Suicidal behavior is an important problem in schizophrenia. Identifying risk factors and high-risk individuals will guide us in the development of preventive interventions.


Assuntos
Esquizofrenia , Psicologia do Esquizofrênico , Tentativa de Suicídio/psicologia , Tentativa de Suicídio/estatística & dados numéricos , Adolescente , Adulto , Idoso , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Acontecimentos que Mudam a Vida , Masculino , Pessoa de Meia-Idade , Transtornos Psicóticos , Estudos Retrospectivos , Tentativa de Suicídio/prevenção & controle , Fatores de Tempo , Turquia/epidemiologia , Adulto Jovem
18.
An. psicol ; 35(2): 204-213, mayo 2019. tab
Artigo em Inglês | IBECS | ID: ibc-181690

RESUMO

The chronic phase of schizophrenia is characterized by illness progression and patients encountering difficulties to return to premorbid level of functioning. The objective of this study was to describe the characteristics of a sample of patients with chronic schizophrenia, as well to assess differences between patients under and over 45 years of age. In a clinical sample of 77 chronic schizophrenia patients, we assessed basic symptoms, cognitive performance, social functioning and quality of life. All participants obtained very high scores in residual symptoms, and no differences in sociodemographic or clinical characteristics between the age groups were found. Younger patients had better cognitive performance and older patients obtained better scores for social functioning and quality of life. Number of psychotropic drugs, verbal learning delayed of SCIP, errors in WCST, Similarities and Digit Symbol Coding of WAIS were the most important variables to predict global functioning of patients over 45 years old. Increasing our understanding of differences in characteristics of the chronic phase of the illness and the profile of functioning at different ages, may help us design intervention strategies to improve adaptation in young and middle-aged patients with chronic schizophrenia


La fase crónica de la esquizofrenia se caracteriza por la progresión de la enfermedad y por las dificultades que presentan los pacientes para volver al nivel de funcionamiento premórbido. El objetivo de este estudio fue describir las características de una muestra de pacientes con esquizofrenia crónica, y conocer las diferencias entre los pacientes menores y mayores de 45 años. En una muestra clínica de 77 pacientes con esquizofrenia crónica, se han evaluado síntomas básicos, el rendimiento cognitivo, el funcionamiento social y la calidad de vida. Todos los participantes obtuvieron puntuaciones muy altas en los síntomas residuales, y no se encontraron diferencias en las características sociodemográficas o clínicas entre los grupos de edad. Los resultados señalan que los pacientes más jóvenes tienen mejor rendimiento cognitivo, y los mayores, mejor funcionamiento social y calidad de vida. El número de fármacos utilizados, los valores en la escala de aprendizaje verbal diferido del SCIP, los errores en WCST, los subtests de Semejanzas y Dígitos del WAIS fueron las variables que mejor pronostican el funcionamiento global de los pacientes mayores de 45 años. Por lo tanto, aumentar nuestra comprensión de las características de la fase crónica de la enfermedad y el perfil de funcionamiento en función de la edad, puede ayudarnos a diseñar estrategias de intervención para mejorar la adaptación en pacientes jóvenes y de mediana edad con esquizofrenia crónica


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Esquizofrenia/terapia , Psicologia do Esquizofrênico , Psicometria/métodos , Memória de Curto Prazo/classificação , Compreensão , Função Executiva , Resultado do Tratamento , Autorrelato/estatística & dados numéricos , Progressão da Doença , Efeito Idade , Doença Crônica/tendências
19.
Artigo em Russo | MEDLINE | ID: mdl-31089088

RESUMO

AIM: To identify main clinical and psychopathological models of remission in the initial stage of schizophrenia which were correlated with subsequent clinical and social prognosis. MATERIAL AND METHODS: The sample consisted of 116 patients diagnosed with paroxysmal-progressive schizophrenia (ICD-10 items F20.01-F20.09) in remission after the first or second episode. Clinical-psychopathological, psychometric (SPI-A), statistical methods were used. The separation of remissions in the initial stage of schizophrenia was based on the principle of longitudinal observation with estimation of correlations between deficit disorders and positive symptoms. RESULTS AND CONCLUSION: Depending on the predominance of one of the factors of the deficit symptom complex, the following modules were identified: remissions with domination of deficit expression factor and remissions with deficit apathy factor, which were correlated with the clinical and social prognosis.


Assuntos
Esquizofrenia , Psicologia do Esquizofrênico , Humanos , Prognóstico , Psicometria , Psicopatologia , Esquizofrenia/diagnóstico
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA