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Stud Health Technol Inform ; 281: 1104-1105, 2021 May 27.
Artigo em Inglês | MEDLINE | ID: mdl-34042858


For a research project on mass spectrometry, a streamlined, harmonized and robust analytical pipeline is built to predict tumor recurrence. By means of standardization all steps from sample collection, analysis, proteome, and metabolome analysis are harmonized. Challenges like non-central identificators and distributed data are overcome with a centralized high-performant IT-platform in combination with a pseudonymization service and harmonization.

Gerenciamento de Dados , Análise de Sistemas , Espectrometria de Massas , Padrões de Referência , Relatório de Pesquisa
Stud Health Technol Inform ; 279: 62-69, 2021 May 07.
Artigo em Inglês | MEDLINE | ID: mdl-33965920


In healthcare studies, the analysis of claims data is gaining an increasingly important role. Observational studies should be reported in a manner that promotes internal and external validity assessment, with the exact and standardized description of items. Several international guidelines and checklists for reporting on secondary data are available. The aim of this work was to analyse the applicability of reporting guidelines especially for claims data. The STROSA-2 guidelines recommendations were evaluated by means of a report on a study on triptan medications in Austria. Six items were identified which could be expanded to support complete and transparent report on Austrian claims data. Therefore, we would suggest to add some details in the STROSA-2 guidelines concerning study design, legal foundations, data protection, data flow, descriptive results and risk of bias. The guidelines for reporting on Austrian claims data were successfully compiled with additional items. New guidelines should be further processed and tested with strong recommendations to focus on data limitations and legal aspects.

Lista de Checagem , Relatório de Pesquisa , Áustria , Atenção à Saúde , Projetos de Pesquisa
Z Evid Fortbild Qual Gesundhwes ; 163: 76-84, 2021 Jun.
Artigo em Alemão | MEDLINE | ID: mdl-34023244


BACKGROUND: Although several tools to evaluate the credibility of health care guidelines exist, guidance on practical steps for developing guidelines is lacking. We systematically compiled a comprehensive checklist of items linked to relevant resources and tools that guideline developers could consider, without the expectation that every guideline would address each item. METHODS: We searched data sources, including manuals of international guideline developers, literature on guidelines for guidelines (with a focus on methodology reports from international and national agencies, and professional societies) and recent articles providing systematic guidance. We reviewed these sources in duplicate, extracted items for the checklist using a sensitive approach and developed overarching topics relevant to guidelines. In an iterative process, we reviewed items for duplication and omissions and involved experts in guideline development for revisions and suggestions for items to be added. RESULTS: We developed a checklist with 18 topics and 146 items and a webpage to facilitate its use by guideline developers. The topics and included items cover all stages of the guideline enterprise, from the planning and formulation of guidelines, to their implementation and evaluation. The final checklist includes links to training materials as well as resources with suggested methodology for applying the items. INTERPRETATION: The checklist will serve as a resource for guideline developers. Consideration of items on the checklist will support the development, implementation and evaluation of guidelines. We will use crowdsourcing to revise the checklist and keep it up to date.

Lista de Checagem , Atenção à Saúde , Alemanha , Relatório de Pesquisa
AMA J Ethics ; 23(3): E271-275, 2021 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-33818380


The Flexner Report damaged and marginalized historically Black medical schools, which today produce more than their fair share of Black medical graduates. As physicians, graduates of Black medical schools have confronted head-on the inequities of American responses to COVID-19 that the pandemic has laid bare to the world. Black physicians' leadership roles in American health care and in American communities have informed the reimagination of health care and medical education as just and inclusive.

Afro-Americanos/educação , Racismo/história , Relatório de Pesquisa , Faculdades de Medicina/história , História do Século XX , Humanos
Health Qual Life Outcomes ; 19(1): 130, 2021 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-33892744


BACKGROUND: The number of research articles on health-related quality of life (HRQoL) has been strikingly increasing. This study aimed to explore the general trends and hotspots of HRQoL. METHODS: Based on the Web of Science database, research on HRQoL published between 2000 and 2019 were identified. A bibliometric analysis was performed based on the number of articles, citations, published journals, authors' addresses, and keywords. Descriptive analysis, visualization of geographic distribution and keyword clustering analysis were applied to the collected data. RESULTS: The annual number of articles showed growth over the past twenty years, but the annual total citations and annual citations per article were both in decreasing trends. Articles about HRQoL were more likely to be published in journals of multi-subject categories. The HRQoL research was mainly distributed across North America and Europe throughout the twenty years and ushered in a vigorous development worldwide after 2015. Cooperation strength between domestic institutions was much greater than that of international institutions. HRQoL research had six concentrated clusters: HRQoL, Depression, Obesity, Disability, Oncology, Fatigue. CONCLUSION: This study provided an overall perspective of global research trends and hotspots in HRQoL, and a potential insight for future research. HRQoL research had experienced significant increasing development during 2000-2019, especially the HRQoL measurement instruments, however, there were significant regional disparities in scientific output in HRQoL.

Bibliometria , Pesquisa Biomédica/estatística & dados numéricos , Pesquisa Biomédica/tendências , Publicações Periódicas como Assunto/estatística & dados numéricos , Publicações Periódicas como Assunto/tendências , Qualidade de Vida/psicologia , Relatório de Pesquisa/tendências , Europa (Continente) , Previsões , Humanos , América do Norte
Int J Surg ; 88: 105918, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33789825


The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, first published in 2009 [1], was developed in an attempt to increase the clarity, transparency, quality and value of these reports [2]. The 27-item checklist and four-phase flow diagram have become the hallmark of academic rigour in the publication of systematic reviews and meta-analyses, having been cited by over 60,000 papers [3]. These are frequently endorsed by journals in their 'Instructions to Authors' [4]. Developments in the methodology and terminology used when conducting systematic reviews [5], alongside the identification of limitations responsible for poor adherence, such as the use of ambiguous wording [6], have warranted an update to the PRISMA statement. The PRISMA 2020 statement, therefore, is intended to reflect this recent evolution in the identification, selection, appraisal and synthesis of research [7]. Here, we present an interpretive analysis of the updated statement, with a view towards encouraging its adoption by both journals and authors in the pursuit of advancing evidence-based medicine.

Guias como Assunto , Relatório de Pesquisa/normas , Revisões Sistemáticas como Assunto , Lista de Checagem , Humanos , Editoração
Int J Surg ; 88: 105906, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33789826


The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology have necessitated an update to the guideline. The PRISMA 2020 statement replaces the 2009 statement and includes new reporting guidance that reflects advances in methods to identify, select, appraise, and synthesise studies. The structure and presentation of the items have been modified to facilitate implementation. In this article, we present the PRISMA 2020 27-item checklist, an expanded checklist that details reporting recommendations for each item, the PRISMA 2020 abstract checklist, and the revised flow diagrams for original and updated reviews.

Guias como Assunto , Relatório de Pesquisa/normas , Revisões Sistemáticas como Assunto , Lista de Checagem , Humanos , Editoração
Cardiovasc Diabetol ; 20(1): 75, 2021 03 31.
Artigo em Inglês | MEDLINE | ID: mdl-33789663


The 6th Cardiovascular Outcome Trial (CVOT) Summit "Cardiovascular and Renal Outcomes 2020" was the first to be held virtually on October 29-30, 2020. As in previous years, this summit served as reference meeting for in-depth discussions on the topic of recently completed and presented major outcome trials. This year, focus was placed on the outcomes of VERTIS-CV, EMPEROR-Reduced, DAPA-CKD, and FIDELIO-DKD. Trial implications for diabetes management and the impact on new treatment algorithms were highlighted for diabetologists, cardiologists, endocrinologists, nephrologists, and general practitioners. Discussion evolved from major outcome trials using SGLT-2 inhibitors for treatment and prevention of heart failure and chronic kidney disease in people with and without diabetes, to additional therapy options for chronic kidney disease with a novel mineralocorticoid receptor antagonist. Furthermore, challenges in diabetes management like COVID-19 and obesity, as well as novel treatment strategies and guidelines, were discussed.The 7th Cardiovascular Outcome Trial Summit will be held virtually on November, 18-19, 2021 ( ).

COVID-19/epidemiologia , Doenças Cardiovasculares/epidemiologia , Ensaios Clínicos como Assunto/métodos , Congressos como Assunto/tendências , Insuficiência Renal Crônica/epidemiologia , Relatório de Pesquisa/tendências , COVID-19/terapia , Doenças Cardiovasculares/terapia , Diabetes Mellitus Tipo 2/epidemiologia , Diabetes Mellitus Tipo 2/terapia , Humanos , Rim/efeitos dos fármacos , Rim/fisiologia , Antagonistas de Receptores de Mineralocorticoides/administração & dosagem , Insuficiência Renal Crônica/terapia , Inibidores do Transportador 2 de Sódio-Glicose/administração & dosagem , Resultado do Tratamento
Artigo em Japonês | MEDLINE | ID: mdl-33883377
Nursing (Säo Paulo) ; 24(275): 5496-5505, abr.-2021.
Artigo em Português | LILACS, BDENF - Enfermagem | ID: biblio-1223897


Objetivo: descrever a experiência de uma atividade lúdica para reflexão da técnica de higienização das mãos entre profissionais de enfermagem frente ao atendimento de paciente com Coronavírus. Método: trata-se do estudo de um relato de experiência profissional sobre uma atividade educativa realizada com 25 profissionais que estão na linha de frente do COVID-19. Resultado: os participantes perceberam as falhas durante o procedimento de higienização das mãos e foram esclarecidos sobres as principais dúvidas sobre a técnica correta, tempo de fricção, quantidade de sabão a ser utilizado, fazendo com que suas práticas fossem postas à prova. Conclusão: a educação permanente é primordial para incentivar e realizar as técnicas adequadas, principalmente as que se referem às barreiras de exposição ao vírus. O aumento da qualidade na higienização das mãos, exige investimento na educação continuada para os profissionais de saúde e mudanças dos aspectos relacionados às crenças e à cultura desses profissionais.(AU)

Objective: to describe the experience of a playful activity to reflect on the hand hygiene technique among nursing professionals regarding the care of patients with Coronavirus. Method: this is a study of a professional experience report about an educational activity carried out with 25 professionals who are on the front line of COVID-19. Result: the participants realized the flaws during the hand hygiene procedure and were clarified about the main doubts about the correct technique, friction time, amount of soap to be used, causing their practices to be put to the test. Conclusion: the permanent education is essential to encourage and carry out appropriate techniques, mainly those related to the barriers of exposure to the virus. The increasing in quality of hand hygiene requires investment in continuing education for health professionals and changes in the aspects related to the beliefs and culture of these professionals.(AU)

Objetivo: describir la experiencia de una actividad lúdica para reflexión sobre la técnica de higienización de las manos entre profesionales de enfermería en relación al cuidado de pacientes con Coronavirus. Método: se trata de un estudio de un informe de experiencia profesional sobre una actividad educativa realizada con 25 profesionales que se encuentran en la primera línea del COVID-19. Resultado: los participantes se notaron las fallas durante el procedimiento de higienización de las manos y se aclararon las principales dudas sobre la técnica correcta, tiempo de fricción, cantidad de jabón a utilizar, haciendo con que sus prácticas sean puestas a prueba. Conclusión: la educación permanente es fundamental para incentivar y realizar las técnicas adecuadas, principalmente aquellos que se refieren a barreras de exposición al virus. El incremento de la calidad de la higienización de las manos requiere inversiones en educación continua para los profesionales de la salud y cambios en los aspectos relacionados con las creencias y la cultura de estos profesionales.(AU)

Humanos , Jogos e Brinquedos , Educação em Saúde/métodos , Infecções por Coronavirus/prevenção & controle , Higiene das Mãos , Profissionais de Enfermagem , Relatório de Pesquisa , Pandemias
Nursing (Säo Paulo) ; 24(275): 5506-5513, abr.-2021.
Artigo em Português | LILACS, BDENF - Enfermagem | ID: biblio-1223905


Este artigo tem como objetivo relatar a elaboração de um Planejamento Estratégico Situacional (PES) realizado por profissionais residentes. Trata-se de um relato de experiência onde os encontros realizados para a elaboração do PES iniciou no dia 1 de outubro de 2016 e se deu até 31 de janeiro de 2017. Os dados foram coletados nos meses de outubro a novembro de 2016 em seis momentos, utilizou como metodologias as estratégias de rodas de conversa e exposição dialogada. O alto índice de pacientes com hipertensão arterial e diabetes mellitus foi o resulto encontrado, tendo como discursão a garantia do acompanhamento integral deste público supracitado e a baixa adesão as consultas de hipertensão arterial e diabetes mellitus. Para os profissionais residentes a realização do PES foi essencial para formação profissional, visto que essa ferramenta de trabalho despertou uma reflexão sobre as formas de assistência prestada pelos profissionais da Atenção Básica.(AU)

This article aims to report the development of a Situational Strategic Planning (PES) carried out by resident professionals. This is an experience report where the meetings held for the preparation of the PES started on October 1, 2016 and took place until January 31, 2017. Data were collected from October to November 2016 in six moments , used as methodologies the strategies of conversation circles and dialogued exposition. The high rate of patients with arterial hypertension and diabetes mellitus was the result found, having as a discourse the guarantee of full monitoring of this aforementioned public and the low adherence to hypertension and diabetes mellitus consultations. For resident professionals, the performance of the PES was essential for professional training, since this work tool aroused a reflection on the forms of assistance provided by Primary Care professionals.(AU)

Este artículo tiene como objetivo informar del desarrollo de una Planificación Estratégica Situacional (PES) realizada por profesionales residentes. Se trata de un relato de experiencia donde las reuniones realizadas para la elaboración del PES comenzaron el 1 de octubre de 2016 y se llevaron a cabo hasta el 31 de enero de 2017. Se recolectaron datos de octubre a noviembre de 2016 en seis momentos, se utilizaron como metodologías las estrategias de los círculos de conversación y exposición dialogada. La alta tasa de pacientes con hipertensión arterial y diabetes mellitus fue el resultado encontrado, teniendo como discurso la garantía de un seguimiento completo de este público mencionado y la baja adherencia a las consultas de hipertensión arterial y diabetes mellitus. Para los profesionales residentes, la actuación de los SPE fue fundamental para la formación profesional, ya que esta herramienta de trabajo suscitó una reflexión sobre las formas de atención que prestan los profesionales de Atención Primaria.(AU)

Humanos , Atenção Primária à Saúde , Planejamento Estratégico , Centros de Saúde , Saúde da Família , Encaminhamento e Consulta , Relatório de Pesquisa
Pharm. pract. (Granada, Internet) ; 19(1): 0-0, ene.-mar. 2021. tab
Artigo em Inglês | IBECS | ID: ibc-ET2-8306


Scholarly publishing is in a crisis, with the many stakeholders complaining about different aspects of the system. Authors want fast publication times, high visibility and publications in high-impact journals. Readers want freely accessible, high-quality articles. Peer reviewers want recognition for the work they perform to ensure the quality of the published articles. However, authors, peer reviewers, and readers are three different roles played by the same group of individuals, the users of the scholarly publishing system-and this system could work based on a collaborative publishing principle where "nobody pays, and nobody gets paid"

No disponible

Humanos , Autoria/normas , Pesquisa Biomédica/normas , Revisão por Pares/normas , Publicação de Acesso Aberto/normas , Comportamento Cooperativo , Publicações Periódicas como Assunto/normas , Relatório de Pesquisa/normas , Publicação Periódica , Sistemas de Avaliação das Publicações
CMAJ Open ; 9(1): E295-E301, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33785477


BACKGROUND: The quality of case reports, which are often the first reported evidence for a disease, may be negatively affected by a rush to publication early in a pandemic. We aimed to determine the completeness of reporting (COR) for case reports published on coronavirus disease 2019 (COVID-19). METHODS: We conducted a systematic search of the PubMed database for all single-patient case reports of confirmed COVID-19 published from Jan. 1 to Apr. 24, 2020. All included case reports were assessed for adherence to the CARE (Case Report) 31-item checklist, which was used to create a composite COR score. The primary outcome was the mean COR score assessed by 2 independent raters. Secondary outcomes included whether there was a change in overall COR score with certain publication factors (e.g., publication date) and whether there was a linear relation between COR and citation count and between COR scores and social media attention. RESULTS: Our search identified 196 studies that were published in 114 unique journals. We found that the overall mean COR score was 54.4%. No one case report included all of the 31 CARE checklist items. There was no significant correlation between COR with either citation count or social media attention. INTERPRETATION: We found that the overall COR for case reports on COVID-19 was poor. We suggest that journals adopt common case-reporting standards to improve reporting quality.

COVID-19/epidemiologia , Lista de Checagem/normas , Editoração/normas , Relatório de Pesquisa/normas , Bibliografia de Medicina , Bibliometria , COVID-19/diagnóstico , COVID-19/virologia , Gerenciamento de Dados , Estudos Epidemiológicos , Ética , Fidelidade a Diretrizes , Humanos , Avaliação de Resultados em Cuidados de Saúde , Relatório de Pesquisa/tendências , SARS-CoV-2/genética , SARS-CoV-2/isolamento & purificação , Mídias Sociais/estatística & dados numéricos
GMS J Med Educ ; 38(2): Doc36, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33763521


Aim: The seminar program of the KWBW Verbundweiterbildungplus® is offered by the Competence Center for Postgraduate Medical Education in Baden-Württemberg (KWBW) for physicians specializing in general practice (GP trainees). Attendance is a voluntary one comprised of 48 curricular units of 45 minutes each per GP trainee. This seminar program is meant to be attended in parallel to the postgraduate medical education in clinic or practice. The intention behind this project was to develop objectives, topics and a feasible structure for a seminar curriculum while taking time and financial constraints into account. Method: The Kern cycle was applied in an open, modified nominal group consensus technique in the form of an iterative process. Participating were 17 experts from the departments of general practice at the universities in Freiburg, Heidelberg, Tuebingen and Ulm, plus a pediatrician. Results: The main objective was defined as empowering GP trainees to independently provide high-quality primary care, including in rural areas. A basic curriculum was defined based on relevant frameworks, such as the 2018 Model Regulation for Postgraduate Medical Training (Musterweiterbildungsordnung/MWBO) and the Competency-based Curriculum General Practice (KCA). Overall, the seminar curriculum has 62 basic modules with 2 curricular units each (e.g. Basic Principles of General Practice, Chest Pain, Billing) and another 58 two-unit modules on variable topics (e.g. digitalization, travel medicine) adding up to 240 (124+116) curricular units. A blueprint with a rotation schedule for all of the teaching sites in Baden-Württemberg allows regular attendance by n=400 GP trainees over a period of five years, with individual variability in terms of program length. Conclusion: The model entails a five-year, flexible program to accompany the postgraduate medical education in general practice which can also be implemented in multicenter programs and those with high enrollments. The model's focus is on acquisition of core competencies for general practice. Despite the current shift to eLearning seminars due to SARS-CoV, the program's implementation is being continued, constantly evaluated, and used to further develop the KWBW Verbundweiterbildungplus® program.

Competência Clínica , Currículo , Educação de Pós-Graduação em Medicina , Medicina Geral/educação , Clínicos Gerais/educação , Universidades , Alemanha , Humanos , Relatório de Pesquisa
Mycopathologia ; 186(2): 155-162, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-33704625


The 2020 COVID-19 pandemic had a profound impact on the publishing landscape. The 'pre-peer-review' publication model is likely to become common as a lag in publishing is not acceptable in a pandemic or other time! Mycopathologia is well placed to adopt such changes with its improved editorial processes, article formats, author engagements, and published articles' access and citation. Mycopathologia had an improved journal impact factor and article downloads in 2018-2019. A limited sampling suggested a slight decrease in the total submissions in 2019 (352 articles) compared to 2018 (371 articles). However, the acceptance rate improved to 30% in 2019 from 19% in 2018. Nearly half of all submissions in 2019 were rejected before peer-review or transferred to other Springer Nature journals. The published articles were contributed from 34 different countries, with authors from China, the USA, and Brazil among the top three contributors. An enhanced editorial oversight allowed peer-reviewers to focus on fewer articles that were well-matched to their expertise, which led to lower rejection rates post-peer-review. The introduction of MycopathologiaGENOME and MycopathologiaIMAGE article types received a good reception with notable downloads and citations.

COVID-19 , Micologia , Patologia , Revisão da Pesquisa por Pares/normas , Publicações Periódicas como Assunto/estatística & dados numéricos , Publicações Periódicas como Assunto/normas , Relatório de Pesquisa/normas , Guias como Assunto , Humanos , Fator de Impacto de Revistas , Pandemias , SARS-CoV-2