Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 212
Filtrar
1.
Environ Health Prev Med ; 24(1): 61, 2019 Oct 22.
Artigo em Inglês | MEDLINE | ID: mdl-31640568

RESUMO

BACKGROUND: Chemical intolerance (CI) is a chronic condition characterized by recurring and severe symptoms triggered by exposure to low levels of odorous or pungent substances. The etiology of CI has been a controversial subject for a long time. The aim of this review is to summarize findings on the neurological processing of sensory information during and after exposure to low levels of odorous or pungent substances in individuals with CI, focusing on the brain function and networks. METHODS: Scientific studies on CI published between 2000 and 2019 in academic peer-reviewed journals were systematically searched using medical and scientific literature databases. Only peer-reviewed articles reporting original research from experimental human studies directly associated with CI, and involving related neurological responses or brain imaging after exposure to odorous or pungent substances (i.e., in chemical provocation tests), were considered. RESULTS: Forty-seven studies were found to be eligible for a full-text review. Twenty-three studies met the selection criteria and were included in this review. Evidence indicated that differences between subjects with CI and healthy controls were observed by brain imaging during and after exposure to odorous or pungent substances. Differences in brain imaging were also observed between initial exposure and after exposure to these substances. Neurological processing of sensory information after exposure to extrinsic stimuli in the limbic system and related cortices were altered in subjects with CI. A previous documentable exposure event was likely to be involved in this alteration. CONCLUSIONS: This review documents consistent evidence for the altered neurological processing of sensory information in individuals with CI. Further neurophysiological research exploring the processing of extrinsic stimuli and cognition of sensation through the limbic system and related cortices in CI, and the appearance of symptoms in individuals with CI, are required.


Assuntos
Encéfalo/fisiopatologia , Substâncias Perigosas , Sensibilidade Química Múltipla/fisiopatologia , Sensibilidade Química Múltipla/psicologia , Percepção Olfatória/fisiologia , Encéfalo/diagnóstico por imagem , Encéfalo/fisiologia , Suscetibilidade a Doenças , Exposição Ambiental , Humanos , Sensibilidade Química Múltipla/diagnóstico por imagem , Odorantes , Condutos Olfatórios/diagnóstico por imagem , Condutos Olfatórios/fisiopatologia , Transtornos Psicofisiológicos/diagnóstico por imagem , Transtornos Psicofisiológicos/fisiopatologia , Transtornos Psicofisiológicos/psicologia
2.
Ideggyogy Sz ; 72(5-6): 165-170, 2019 May 30.
Artigo em Inglês | MEDLINE | ID: mdl-31241260

RESUMO

Background and purpose: Two trait-like characteristics, somatosensory amplification and absorption, have been associated with symptom reports and idiopathic environmental intolerances in past research. Purpose - As the two constructs are not connected with each other, their independent contribution to symptom reports and electromagnetic hypersensitivity, as well as their interaction can be expected. Methods: On-line questionnaire. Patients - 506 college students completed an on-line questionnaire assessing absorption, somatosensory amplification, negative affect, somatic symptoms, and electromagnetic hypersensitivity. Results: Somatosensory amplification (ß = 0.170, p < 0.001) and absorption (ß = 0.128, p < 0.001) independently contributed to somatic symptoms after controlling for gender and negative affect (R2 = 0.347, p < 0.001). Similarly, somatosensory amplification (OR = 1.082, p < 0.05) and absorption (OR = 1.079, p < 0.01) independently contributed to electromagnetic hypersensitivity after controlling for somatic symptoms, gender, and negative affect (Nagelkerke R2 = 0.134, p < 0.001). However, no interaction effects were found. Conclusion: Somatosensory amplification and absorption independently contribute to symptom reports and electromagnetic hypersensitivity. Conclusion - The findings suggest that psychological mechanisms underlying symptom reports and electromagnetic hypersensitivity might be heterogeneous.


Assuntos
Ansiedade/psicologia , Campos Eletromagnéticos/efeitos adversos , Sensibilidade Química Múltipla/diagnóstico , Distúrbios Somatossensoriais/psicologia , Estudantes/psicologia , Ansiedade/complicações , Ansiedade/fisiopatologia , Humanos , Sensibilidade Química Múltipla/etiologia , Sensibilidade Química Múltipla/psicologia , Transtornos Somatoformes/psicologia , Distúrbios Somatossensoriais/complicações , Distúrbios Somatossensoriais/fisiopatologia , Inquéritos e Questionários
3.
Int Arch Occup Environ Health ; 91(8): 923-935, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30088144

RESUMO

PURPOSE: Multiple chemical sensitivity (MCS) also known as idiopathic environmental intolerance/illness (IEI) encompasses a cohort of subjective symptoms characterized by susceptibility to a wide spectrum of environmental compounds, causing symptoms involving various organs and a decrease in quality of life. The aim of this systematic review is to summarize evidence about MCS, with focus on indexed studies analyzing sensory pathway-related disorders. METHODS: Medical databases were searched for English language articles related to the topic, published between 1965 and 2017 in academic, peer-reviewed journals. Particular focus was concentrated on articles depicting disturbances involving sensory organs. References of the relevant articles were examined to identify additional significant documents. RESULTS: Fifty-eight studies were eligible for full text review. Of these, 34 studies met the selection criteria and were included in this analysis. Many variables, such as different diagnostic criteria, lack of homogeneous symptom questionnaires and the general incidence of personality traits in control subjects, biased studies as confounding factors. However, moderate evidences show that sensory pathways are somewhat altered, especially with respect to information processing in the limbic system and related cortical areas. Recent studies suggested the presence, in MCS cohorts, of attention bias, sensitization and limbic kindling, as well as recently revealed subclinical organic alterations along sensory pathways. CONCLUSIONS: Evidences are consistent with MCS/IEI to be the result of a neural altered processing of sensorial ascending pathways, which combined with peculiar personality traits constitutes the underpinning of a multisensory condition needing multidisciplinary clinical approach.


Assuntos
Sensibilidade Química Múltipla/psicologia , Transtornos da Percepção/psicologia , Humanos , Transtornos da Percepção/complicações , Personalidade
4.
Environ Res ; 166: 409-417, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-29936289

RESUMO

While there has been consistent evidence that symptoms reported by individuals who suffer from Idiopathic Environmental Intolerance attributed to Electromagnetic Fields (IEI-EMF) are not caused by EMF and are more closely associated with a nocebo effect, whether this response is specific to IEI-EMF sufferers and what triggers it, remains unclear. The present experiment tested whether perceived EMF exposure could elicit symptoms in healthy participants, and whether viewing an 'alarmist' video could exacerbate a nocebo response. Participants were randomly assigned to watch either an alarmist (N = 22) or control video (N = 22) before completing a series of sham and active radiofrequency (RF) EMF exposure provocation trials (2 open-label, followed by 12 randomized, double-blind, counterbalanced trials). Pre- and post-video state anxiety and risk perception, as well as belief of exposure and symptom ratings during the open-label and double-blind provocation trials, were assessed. Symptoms were higher in the open-label RF-ON than RF-OFF trial (p < .001). No difference in either symptoms (p = .183) or belief of exposure (p = .144) was observed in the double-blind trials. Participants who viewed the alarmist video had a significant increase in symptoms (p = .041), state anxiety (p < .01) and risk perception (p < .001) relative to the control group. These results reveal the crucial role of awareness and belief in the presentation of symptoms during perceived exposure to EMF, showing that healthy participants exhibit a nocebo response, and that alarmist media reports emphasizing adverse effects of EMF also contribute to a nocebo response.


Assuntos
Campos Eletromagnéticos/efeitos adversos , Sensibilidade Química Múltipla/psicologia , Efeito Nocebo , Método Duplo-Cego , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Ondas de Rádio , Sugestão , Gravação em Vídeo
5.
J Occup Environ Med ; 60(2): 138-146, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29111991

RESUMO

OBJECTIVE: Systematic bibliography analysis of about the last 17 years on multiple chemical sensitivity (MCS) was carried out in order to detect new diagnostic and epidemiological evidence. The MCS is a complex syndrome that manifests as a result of exposure to a low level of various common contaminants. The etiology, diagnosis, and treatment are still debated among researchers. METHOD: Querying PubMed, Web of Science, Scopus, Cochrane library, both using some specific MESH terms combined with MESH subheadings and through free search, even by Google. RESULTS: The studies were analyzed by verifying 1) the typology of study design; 2) criteria for case definition; 3) presence of attendances in the emergency departments and hospital admissions, and 4) analysis of the risk factors. OUTLOOK: With this review, we give some general considerations and hypothesis for possible future research.


Assuntos
Sensibilidade Química Múltipla/diagnóstico , Sensibilidade Química Múltipla/epidemiologia , Serviço Hospitalar de Emergência , Hospitalização , Humanos , Estudos Longitudinais , Sensibilidade Química Múltipla/fisiopatologia , Sensibilidade Química Múltipla/psicologia , Estudos Observacionais como Assunto , Fatores de Risco
6.
Med Anthropol Q ; 32(2): 214-232, 2018 06.
Artigo em Inglês | MEDLINE | ID: mdl-28726292

RESUMO

Sufferers of medically unexplained conditions that are not observable in the clinic can experience multiple layers of invisibility: a lack of biomedical diagnosis; legal skepticism; political disinterest; and a loss of their prior social identity. For those with environmental sensitivities, this is compounded by literal hiddenness due to often being housebound. Drawing on an online survey of people with multiple chemical sensitivity, this article examines how the everyday experience of invisibility is mitigated by engaging with other patients online. Respondents used online forums to undertake various forms of "visibility work," including attempts to crystallize their suffering into something recognizable medically, legally, and politically, and to reconstruct an identity considered valid and deserving-although the therapeutic potential of online support was contingent on intra-group politics. This study demonstrates that online forums allow biomedicine's "invisible others" to struggle for alternative forms of recognition beyond the clinical gaze.


Assuntos
Internet , Sensibilidade Química Múltipla/psicologia , Sensibilidade Química Múltipla/terapia , Grupos de Autoajuda , Identificação Social , Adulto , Idoso , Antropologia Médica , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
7.
Environ Res ; 156: 265-271, 2017 07.
Artigo em Inglês | MEDLINE | ID: mdl-28371755

RESUMO

People suffering from idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) experience numerous non-specific symptoms that they attribute to EMF. The cause of this condition remains vague and evidence shows that psychological rather than bioelectromagnetic mechanisms are at work. We hypothesized a role of media reports in the etiology of IEI-EMF and investigated how somatosensory perception is affected. 65 healthy participants were instructed that EMF exposure can lead to enhanced somatosensory perception. Participants were randomly assigned to watch either a television report on adverse health effects of EMF or a neutral report. During the following experiment, participants rated stimulus intensities of tactile (electric) stimuli while being exposed to a sham WiFi signal in 50% of the trials. Sham WiFi exposure led to increased intensity ratings of tactile stimuli in the WiFi film group, especially in participants with higher levels of somatosensory amplification. Participants of the WiFi group reported more anxiety concerning WiFi exposure than the Control group and tended to perceive themselves as being more sensitive to EMF after the experiment compared to before. Sensational media reports can facilitate enhanced perception of tactile stimuli in healthy participants. People tending to perceive bodily symptoms as intense, disturbing, and noxious seem most vulnerable. Receiving sensational media reports might sensitize people to develop a nocebo effect and thereby contribute to the development of IEI-EMF. By promoting catastrophizing thoughts and increasing symptom-focused attention, perception might more readily be enhanced and misattributed to EMF.


Assuntos
Ansiedade/epidemiologia , Campos Eletromagnéticos/efeitos adversos , Sintomas Inexplicáveis , Sensibilidade Química Múltipla/psicologia , Tato , Tecnologia sem Fio , Adolescente , Adulto , Ansiedade/etiologia , Feminino , Alemanha/epidemiologia , Humanos , Masculino , Distribuição Aleatória , Televisão , Adulto Jovem
8.
Psychiatry Res ; 249: 187-194, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28113122

RESUMO

Idiopathic Environmental Intolerance (IEI) has been associated with psychogenic factors and an increased number of comorbid psychiatric disorders such as depression and anxiety disorder. The purpose of the current study was to examine a possible overlap of psychological and somatic symptoms between subjects with IEI and patients with major depression and schizophrenia as well as to specify characteristic differences. The different symptom clusters included symptoms of chemical intolerance, neurotoxicity and psychological distress as well as measurements of mental health such as anxiety, depression, somatoform symptoms, and schizophrenia-specific disturbances in cognitive domains. IEI patients reported higher overall levels in physical symptoms such as chemical intolerance, neurotoxicity and somatic symptoms not attributable to an organic cause. Schizophrenia patients showed higher overall levels in self-experienced disturbances in several schizophrenia-specific cognitive domains, whereas general psychological distress, anxiety and depression were rated highest by patients with major depression. Importantly, the groups markedly differed in the shapes of profiles of various symptom clusters. Our results provide evidence that IEI patients can be distinguished on the phenomenological level from patients with major depression or schizophrenia, and that distinct domains of psychological and somatic symptoms are particularly problematic in specific diagnostic groups.


Assuntos
Transtorno Depressivo Maior/complicações , Sensibilidade Química Múltipla/complicações , Transtornos Somatoformes/complicações , Adulto , Ansiedade/complicações , Ansiedade/diagnóstico , Ansiedade/psicologia , Depressão/complicações , Depressão/diagnóstico , Depressão/psicologia , Transtorno Depressivo Maior/diagnóstico , Transtorno Depressivo Maior/psicologia , Feminino , Humanos , Masculino , Sintomas Inexplicáveis , Pessoa de Meia-Idade , Sensibilidade Química Múltipla/diagnóstico , Sensibilidade Química Múltipla/psicologia , Transtornos Somatoformes/diagnóstico , Transtornos Somatoformes/psicologia , Avaliação de Sintomas
9.
PLoS One ; 11(12): e0168006, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27936122

RESUMO

Multiple chemical sensitivity (MCS) is a disorder characterized by nonspecific and recurrent symptoms from various organ systems associated with exposure to low levels of chemicals. Patients with MCS process odors differently than controls do. Previously, we suggested that this odor processing was associated with increased regional cerebral blood flow (rCBF) in the prefrontal area during olfactory stimulation using near-infrared spectroscopic (NIRS) imaging. The aim of this study was to investigate the association of odor thresholds and changes in rCBF during olfactory stimulation at odor threshold levels in patients with MCS. We investigated changes in the prefrontal area using NIRS imaging and a T&T olfactometer during olfactory stimulation with two different odorants (sweet and fecal) at three concentrations (zero, odor recognition threshold, and normal perceived odor level) in 10 patients with MCS and six controls. The T&T olfactometer threshold test and subjective assessment of irritating and hedonic odors were also performed. The results indicated that the scores for both unpleasant and pungent odors were significantly higher for those for sweet odors at the normal perceived level in patients with MCS than in controls. The brain responses at the recognition threshold (fecal odor) and normal perceived levels (sweet and fecal odors) were stronger in patients with MCS than in controls. However, significant differences in the odor detection and recognition thresholds and odor intensity score between the two groups were not observed. These brain responses may involve cognitive and memory processing systems during past exposure to chemicals. Further research regarding the cognitive features of sensory perception and memory due to past exposure to chemicals and their associations with MCS symptoms is needed.


Assuntos
Circulação Cerebrovascular , Sensibilidade Química Múltipla/fisiopatologia , Odorantes , Córtex Pré-Frontal/irrigação sanguínea , Limiar Sensorial , Adulto , Idoso , Estudos de Casos e Controles , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Sensibilidade Química Múltipla/psicologia , Olfatometria , Espectroscopia de Luz Próxima ao Infravermelho
10.
J Psychosom Res ; 84: 8-12, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27095153

RESUMO

OBJECTIVE: Need for better understanding of the etiology of idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) motivated the present study of psychological symptoms and health-related quality of life (HRQoL) in person who attribute health problems to electromagnetic fields. METHODS: Participants with IEI-EMF (n=114) and a population-based sample of referents (n=104) were investigated with six subscales of the Symptom Checklist 90 (SCL-90) to assess psychological symptoms, and with eight subscales of the Short Form (36) Health Survey (SF-36) to assess HRQoL. RESULTS: Significantly higher scores were found on obsessive/compulsive behavior, interpersonal hypersensitivity, hostility, phobic anxiety, paranoid thoughts in the IEI-EMF group compared to referents, whereas only a tendency of such a difference was found for psychotism. Furthermore, poorer HRQoL in the IEI-EMF group, compared to referents, were found regarding physical and social functioning, physical and emotional role limitations, general health, vitality, bodily pain, and mental health. Significant correlation with moderate to strong effect sizes were found between several of the SCL-90 and SF-36 subscales. CONCLUSION: The results suggest that IEI-EMF is associated with various types of psychological symptoms and with poor HRQoL. Clinical implications include theoretical support for cognitive behavioral therapy, and, although further research is needed, that attention should be directed towards feelings of inferiority and uneasiness in relationships as well as anger, hostility and resentment towards other people.


Assuntos
Campos Eletromagnéticos , Sensibilidade Química Múltipla/psicologia , Qualidade de Vida , Adulto , Ira , Ansiedade/etiologia , Transtorno da Personalidade Compulsiva/psicologia , Emoções , Feminino , Nível de Saúde , Inquéritos Epidemiológicos , Hostilidade , Humanos , Masculino , Pessoa de Meia-Idade , Sensibilidade Química Múltipla/etiologia , Transtornos Paranoides/etiologia , Transtornos Fóbicos/etiologia , Adulto Jovem
11.
Scand J Psychol ; 57(2): 136-43, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26861662

RESUMO

Body focus is often considered an undesirable characteristic from medical point of view as it amplifies symptoms and leads to higher levels of health anxiety. However, it is connected to mindfulness, well-being and the sense of self in psychotherapy. The current study aimed to investigate the contribution of various body focus related constructs to acute and chronic generation and maintenance of medically unexplained symptoms (MUS). Thirty-six individuals with idiopathic environmental intolerance to electromagnetic fields (IEI-EMF) and 36 controls were asked to complete questionnaires assessing negative affect, worries about harmful effects of EMFs, health anxiety (HA), body awareness, and somatosensory amplification (SSA), and to report experienced symptoms evoked by a sham magnetic field. Body awareness, HA, SSA, and EMF-related worries showed good discriminative power between individuals with IEI-EMF and controls. Considering all variables together, SSA was the best predictor of IEI-EMF. In the believed presence of a MF, people with IEI-EMF showed higher levels of anxiety and reported more symptoms than controls. In the IEI-EMF group, actual symptom reports were predicted by HA and state anxiety, while a reverse relationship between symptom reports and HA was found in the control group. Our findings show that SSA is a particularly important contributor to IEI-EMF, probably because it is the most comprehensive factor in its aetiology. IEI-EMF is associated with both a fear-related monitoring of bodily symptoms and a non-evaluative body focus. The identification of dispositional body focus may be relevant for the management of MUS.


Assuntos
Ansiedade/psicologia , Atitude Frente a Saúde , Conscientização , Campos Eletromagnéticos , Sintomas Inexplicáveis , Sensibilidade Química Múltipla/psicologia , Feminino , Corpo Humano , Humanos , Masculino , Inquéritos e Questionários
12.
Med. clín (Ed. impr.) ; 146(3): 108-111, feb. 2016. tab
Artigo em Espanhol | IBECS | ID: ibc-147821

RESUMO

Introducción y objetivo: La sensibilidad química múltiple (.SQM) es un trastorno multisistémico de etiología controvertida que afecta a algunos sujetos al exponerse a productos químicos a concentraciones no perjudiciales. El objetivo de este trabajo es describir las características epidemiológicas, clínicas y psicológicas de una muestra de pacientes con SQM, para un posterior tratamiento grupal específico. Pacientes y método: Estudio descriptivo de los pacientes diagnosticados de SQM en una unidad de toxicología, mediante la administración del cuestionario Quick Environmental Exposure and Sensitivity Inventory, junto con la entrevista estructurada SCID-II, la escala de ansiedad HAS y el test de personalidad tipo A, PCTA. Resultados: Se incluyeron 73 pacientes, con una edad media de 52,6 años (rango 33-77; DE 9,29), siendo 66 mujeres (90,4%). El 53% estaban clasificados como grado i-ii y ii. Sesenta y un pacientes (83%) presentaron algún tipo de comorbilidad, fundamentalmente dolor crónico, fibromialgia y fatiga crónica, con niveles de ansiedad mayores (puntuación media 19,2), predominio de rasgos de personalidad fóbico-evitativo y patrón de conducta tipo A (31,1%). Conclusiones: La SQM afecta principalmente a mujeres de mediana edad, con comorbilidades (dolor crónico, fibromialgia y fatiga crónica), elevada ansiedad y conductas de evitación. Este análisis previo debería ayudar a ofrecer un abordaje psicoterapéutico específico a estos pacientes (AU)


Introduction and objective: Multiple chemical sensitivity (MCS) is a multisystem disorder of controversial etiology, affecting some subjects when exposed to chemicals at no harmful concentrations. The objective of this paper is to describe the epidemiological, clinical and psychological features of a sample of patients with MCS for further specific group treatment. Patiens and method: Descriptive study of patients diagnosed with MCS in a toxicology unit. We administered the Quick Environmental Exposure and Sensitivity Inventory, the structured interview SCID-II, the anxiety scale HAS and the type A personality test, PCTA. Results: Seventy-three patients were included. The mean age was 52,6 years (range 33-77; SD 9.29). Sixty-six were females (90.4%). Fifty-three percent were classified as i-ii and ii grade. Sixty-one patients (83%) presented some type of comorbidity, mainly chronic pain, fibromyalgia and chronic fatigue. They exhibited higher levels of anxiety (average score of 19.2), prevalence of phobic-avoidant traits of personality and type A behavior in 31.1%. Conclusions: MCS affects middle-aged women with comorbidities (chronic pain, fibromyalgia and chronic fatigue) and high anxiety and avoidance behaviors. This preliminary analysis should help provide a specific therapeutic approach to these patients (AU)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Sensibilidade Química Múltipla/complicações , Sensibilidade Química Múltipla/epidemiologia , Sensibilidade Química Múltipla/psicologia , Exposição a Produtos Químicos , Testes de Personalidade/estatística & dados numéricos , Inquéritos e Questionários , Ansiedade/epidemiologia , Transtornos de Ansiedade/epidemiologia , Transtornos de Ansiedade/psicologia , Escala de Ansiedade Manifesta/estatística & dados numéricos , Escala de Ansiedade Manifesta/normas , Comorbidade
13.
Med Clin (Barc) ; 146(3): 108-11, 2016 Feb 05.
Artigo em Espanhol | MEDLINE | ID: mdl-26654553

RESUMO

INTRODUCTION AND OBJECTIVE: Multiple chemical sensitivity (MCS) is a multisystem disorder of controversial etiology, affecting some subjects when exposed to chemicals at no harmful concentrations. The objective of this paper is to describe the epidemiological, clinical and psychological features of a sample of patients with MCS for further specific group treatment. PATIENS AND METHOD: Descriptive study of patients diagnosed with MCS in a toxicology unit. We administered the Quick Environmental Exposure and Sensitivity Inventory, the structured interview SCID-II, the anxiety scale HAS and the type A personality test, PCTA. RESULTS: Seventy-three patients were included. The mean age was 52,6 years (range 33-77; SD 9.29). Sixty-six were females (90.4%). Fifty-three percent were classified as i-ii and ii grade. Sixty-one patients (83%) presented some type of comorbidity, mainly chronic pain, fibromyalgia and chronic fatigue. They exhibited higher levels of anxiety (average score of 19.2), prevalence of phobic-avoidant traits of personality and type A behavior in 31.1%. CONCLUSIONS: MCS affects middle-aged women with comorbidities (chronic pain, fibromyalgia and chronic fatigue) and high anxiety and avoidance behaviors. This preliminary analysis should help provide a specific therapeutic approach to these patients.


Assuntos
Sensibilidade Química Múltipla/epidemiologia , Determinação da Personalidade , Adulto , Distribuição por Idade , Idoso , Ansiedade/epidemiologia , Candidíase Vulvovaginal/epidemiologia , Dor Crônica/epidemiologia , Comorbidade , Síndrome de Fadiga Crônica/epidemiologia , Feminino , Fibromialgia/epidemiologia , Hábitos , Humanos , Entrevista Psicológica , Estilo de Vida , Masculino , Pessoa de Meia-Idade , Sensibilidade Química Múltipla/psicologia , Polimedicação , Índice de Gravidade de Doença , Distribuição por Sexo
14.
J Psychosom Res ; 79(6): 628-34, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26311155

RESUMO

OBJECTIVE: Multiple chemical sensitivity (MCS) is a medically unexplained condition characterized by symptoms from multiple organ systems following the perception of common odorants. The condition can cause severe functional impairment for afflicted individuals. The aim of this study was to assess the effects of mindfulness-based cognitive therapy (MBCT) for individuals with MCS. METHODS: The intention-to-treat sample (ITT) included 69 individuals who had been randomized to either MBCT or treatment as usual (TAU). The primary outcome measure was the Quick Environmental Exposure and Sensitivity Inventory (QEESI), which measures the following aspects of MCS: impact of MCS on daily life, symptoms, and reactions following chemical exposures. Secondary outcome measures included the Brief Illness Perception Questionnaire (BIPQ) and the anxiety and depression subscales of the symptom checklist 92 (SCL-92). Participants were assessed at baseline and post treatment, and at follow-up periods of 6- and 12-months. RESULTS: We found no effect of MBCT on the primary outcome, nor did we find an effect on levels of depression or anxiety. We did, however, find positive changes in illness perceptions, which were sustained at 12-month follow-up. Dropout rates were low, suggesting MBCT was well received and regarded as an acceptable intervention by individuals with MCS. CONCLUSIONS: Overall, these results suggest that MBCT does not change overall illness status in individuals with MCS, but that MBCT positively changes emotional and cognitive representations. Possible explanations for these results are discussed.


Assuntos
Terapia Cognitivo-Comportamental/métodos , Atenção Plena , Sensibilidade Química Múltipla/terapia , Adulto , Ansiedade/psicologia , Ansiedade/terapia , Transtornos de Ansiedade , Cognição , Depressão/psicologia , Depressão/terapia , Transtorno Depressivo , Emoções , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Sensibilidade Química Múltipla/psicologia , Aceitação pelo Paciente de Cuidados de Saúde , Inquéritos e Questionários , Fatores de Tempo , Adulto Jovem
16.
Int J Behav Med ; 22(6): 755-63, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25778471

RESUMO

BACKGROUND: Among people with idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF), a better than random detection ability for a 50-Hz 0.5-mT magnetic field (MF) and a propensity to experience more symptoms than controls was reported in a previous study. PURPOSE: The current study aimed to replicate and clarify these results using a modified experimental design. METHOD: Participants of the provocation experiment were 49 individuals with self-reported IEI-EMF and 57 controls. They completed the questionnaires (symptom expectations, Somatosensory Amplification Scale--SSAS, radiation subscale of the Modern Health Worries Scale--MHWS Radiation) and attempted to detect the presence of the MF directed to their right arm in 20 subsequent 1-min sessions. Symptom reports were registered after each session. RESULTS: Individuals with IEI-EMF as opposed to the control group showed a higher than random detection performance (d' index of signal detection theory), while no difference in their bias (ß index) toward the presence of the MF was found. Predictors of reported symptoms were self-reported IEI-EMF and believed as opposed to actual presence of the MF. People with IEI-EMF reported significantly more symptoms particularly in the believed presence of the MF. IEI-EMF was closely related to MHWS Radiation and SSAS scores. CONCLUSION: People with IEI-EMF might be able to detect the presence of the MF to a small extent; however, their symptom reports are connected to perceived exposure.


Assuntos
Campos Eletromagnéticos/efeitos adversos , Sensibilidade Química Múltipla , Adulto , Ansiedade/fisiopatologia , Exposição Ambiental/efeitos adversos , Feminino , Área de Dependência-Independência , Humanos , Masculino , Sensibilidade Química Múltipla/diagnóstico , Sensibilidade Química Múltipla/etiologia , Sensibilidade Química Múltipla/psicologia , Autorrelato , Inquéritos e Questionários
17.
J Psychosom Res ; 78(5): 509-14, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25758214

RESUMO

OBJECTIVE: Chemical intolerance (CI) is characterised by negative health effects attributed to a heightened responsiveness to common airborne chemicals. This longitudinal study explored the hypothesised role of negative affect in the development and persistence of CI in a general population. METHODS: A general population sample aged 19 to 72 years was examined in 2006-2008 and again in 2011-2012. Longitudinal data on CI were analysed with the purpose of examining baseline negative affect as a risk factor for having developed CI at 5-year follow-up and for reporting persistent CI. Participants were classified as reporting no signs of CI, having symptoms of CI and as being a likely CI case based on self-reported reactions to 11 common chemical exposures, symptoms related to chemical exposures and daily life adjustments attributed to reactions when exposed to chemicals. RESULTS: A total of 69.4% of the participants who had reported CI at baseline also reported CI at follow-up. In participants with no baseline CI, 15.5% reported CI at follow-up and 18.1% reported symptoms related to chemicals but no daily life adjustments. Baseline negative affect was positively and statistically significantly associated with both development and persistence of CI. CONCLUSIONS: Initial reports of CI were found to be persistent over time, and a considerable proportion of the participants with no CI at baseline reported having developed CI after 5 years. The positive association between negative affect and CI at the 5-year follow-up supports negative affect as a possible risk factor for CI.


Assuntos
Sensibilidade Química Múltipla/psicologia , Negativismo , Ajustamento Social , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Fatores de Risco , Autorrelato
18.
Iran J Allergy Asthma Immunol ; 14(1): 19-27, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25530135

RESUMO

The aetiology behind odor-related chronic somatic symptoms (O-RCSS) is unknown, although both immunological and psychiatric causes have been suggested. The aim of this study was to investigate the occurrence of self-reported asthma and hay fever and psychiatric symptoms in individuals having O-RCSS compared to individuals with similar chronic somatic symptoms (CSS) which were not odors-related, and also compared to healthy controls. Data from the Hordaland Health Study were used. 13,799 individuals, 40-45 years, answered a questionnaire including 16 questions related to somatic symptoms. They also indicated if the symptoms were odor-related, and answered questions about asthma and hay fever. Anxiety and depression were measured with the Hospital Anxiety and Depression Scale. 38 (0.6%) men and 106 (1.4%) women had O-RCSS, whereas 88 (1.5%) men and 192 (2.5%) women had CSS. Adjusted logistic regression analyses showed increased odds of self-reported asthma in those with O-RCSS compared to those with CSS (males: 3.81, 1.06-13.8, females: 2.60, 1.05-6.93) and compared to male and female controls (3.56, 1.89-6.68 and 4.81, 1.92-12.1 respectively). Increased odds of self-reported hay fever were in addition seen in females with O-RCSS. There were no differences in psychiatric symptoms between individuals with O-RCSS and CSS, although individuals in both groups showed increased odds compared to male and female controls. Increased occurrence of self-reported asthma was exclusively found among male and females with O-RCSS, compared to CSS and controls. Increased occurrence of psychiatric symptoms was seen both in individuals with O-RCSS and CSS.


Assuntos
Asma/complicações , Sensibilidade Química Múltipla/complicações , Odorantes , Rinite Alérgica Sazonal/complicações , Adulto , Asma/epidemiologia , Asma/psicologia , Depressão/complicações , Depressão/epidemiologia , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Sensibilidade Química Múltipla/epidemiologia , Sensibilidade Química Múltipla/psicologia , Noruega/epidemiologia , Rinite Alérgica Sazonal/epidemiologia , Rinite Alérgica Sazonal/psicologia , Autorrelato
19.
Environ Health Prev Med ; 20(2): 123-9, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25500796

RESUMO

OBJECTIVE: This study was designed to determine the correlation between mental health and multiple chemical sensitivity (MCS). METHOD: The present study was conducted at two companies in 2011; both in Kyushu, Japan. The "subjective symptoms" subscale of the "Self-diagnosis Checklist for Assessment of Workers' Accumulated Fatigue" was used as a mental health subscale. To determine if multiple chemical exposure has an impact on mental health, we composed an original path model using structural equation analysis. RESULT: Our final path model can be regarded as good: CMIN/DF = 1.832, CFI = 0.996, and RMSEA = 0.038, AIC = 71.158. As expected, chemical sensitivity and other chemical sensitivity scores predicted the health effects of multiple chemical exposure (ß = 0.19, 0.64). Mental health was predicted by symptom severity and life impact (ß = 0.56 and 0.12), which were both affected by multiple chemical exposure (ß = 0.38 and 0.89, respectively). CONCLUSION: As far as we are aware, this is the first study using path analysis to explore whether MCS can indicate mental health in worker populations worldwide, and we found a significant causal relationship between them. This could indicate that more focus should be placed on the impact of MCS on mental health in future investigations.


Assuntos
Indústria Manufatureira , Saúde Mental , Sensibilidade Química Múltipla/epidemiologia , Sensibilidade Química Múltipla/psicologia , Exposição Ocupacional , Adulto , Automóveis , Indústria Editorial , Feminino , Humanos , Japão/epidemiologia , Masculino , Saúde Mental/estatística & dados numéricos , Pessoa de Meia-Idade , Sensibilidade Química Múltipla/etiologia , Índice de Gravidade de Doença , Inquéritos e Questionários
20.
Psiquiatr. biol. (Internet) ; 21(3): 119-121, sept.-dic. 2014.
Artigo em Espanhol | IBECS | ID: ibc-129793

RESUMO

Se define la sensibilidad química múltiple (SQM) como un conjunto de manifestaciones clínicas súbitas ante la exposición a productos químicos a bajas dosis que previamente eran bien toleradas. No existe ninguna prueba analítica, ni exploración complementaria específica de confirmación diagnóstica, y la exploración física es normal. Aunque existe frecuentemente comorbilidad asociada depresiva, en la actualidad la mayoría de los estudios no consideran la SQM como una enfermedad psiquiátrica. No cumple ningún criterio DSM-V o CIE-10, y no se puede incluir como trastorno afectivo, somatomorfo, adaptativo o de la personalidad. Se presenta el caso clínico de una paciente diagnosticada de SQM que ha experimentado importante mejoría de los síntomas propios de este trastorno con medicación antidepresiva —tipo ISRS—, permitiendo entrenamiento conductual de afrontamiento ampliamente considerado contraindicado en estos cuadros (AU)


Multiple chemical sensitivity is defined as a set of sudden clinical manifestations on low level exposure to certain chemical previously well-tolerated products. There is no specific analytical test, or complementary examination to confirm the diagnosis, and the physical examination reveals nothing. Although comorbidity is often associated with depression, at present most studies do not consider multiple chemical sensitivity as a psychiatric illness. It does not fulfil the DSM-V or ICD-10 criteria, and may not be included as an affective, somatoform, adaptive or personality disorder. We present the case of a patient diagnosed with multiple chemical sensitivity who has shown a great improvement in these symptoms associated to the disorder with antidepressant medications — selective serotonin reuptake inhibitors (SSRIs), allowing gradual behavioural training of desensitisation, normally considered to be contraindicated in these diseases (AU)


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Sensibilidade Química Múltipla/diagnóstico , Sensibilidade Química Múltipla/tratamento farmacológico , Sensibilidade Química Múltipla/psicologia , Antidepressivos/uso terapêutico , Transtorno da Personalidade Antissocial/complicações , Transtorno da Personalidade Antissocial/diagnóstico , Paroxetina/uso terapêutico , Comorbidade , Psicopatologia/métodos , Psicopatologia/tendências , Qualidade de Vida
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA