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1.
Artigo em Chinês | MEDLINE | ID: mdl-33794620

RESUMO

Chronic subjective tinnitus is an auditory phantom phenomenon perceived by patients only, with no external sound source. It's a common disease and it lacks effective treatments. Sound therapy is an optional treatment which proved to reduce the tinnitus loudness and the negative effects on life. After decades of development, a wide variety of acoustic therapies have been produced, but seldom are likely to thoroughly cure tinnitus. In recent years, some new acoustic treatments based on the hypothesis of mechanisms of tinnitus, are expected to alleviate or even eliminate tinnitus.


Assuntos
Zumbido , Estimulação Acústica , Humanos , Som , Zumbido/terapia , Resultado do Tratamento
2.
Medicine (Baltimore) ; 100(11): e23576, 2021 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-33725923

RESUMO

ABSTRACT: Short-term immobilization leads to fatty muscular degeneration, which is associated with various negative health effects. Based on literature showing very high correlations between MRI Dixon fat fraction and Speed-of-Sound (SoS), we hypothesized that we can detect short-term-immobilization-induced differences in SoS.Both calves of 10 patients with a calf cast on one side for a mean duration of 41 ±â€Š26 days were examined in relaxed position using a standard ultrasound machine. Calf perimeters were measured for both sides. A flat Plexiglas-reflector, placed vertically on the opposite side of the probe with the calf in-between, was used as a timing reference for SoS. SoS was both manually annotated by two readers and assessed by an automatic annotation algorithm. The thickness values of the subcutaneous fat and muscle layers were manually read from the B-mode images. Differences between the cast and non-cast calves were calculated with a paired t test. Correlation analysis of SoS and calf perimeter was performed using Pearson's correlation coefficient.Paired t test showed significant differences between the cast and non-cast side for both SoS (P < .01) and leg perimeter (P < .001). SoS was reduced with the number of days after cast installment (r = -0.553, P = .097). No significant differences were found for muscle layer thickness, subcutaneous fat layer thickness, mean fat echo intensity, or mean muscle echo intensity.Short-term-immobilization led to a significant reduction in SoS in the cast calf compared to the healthy calf, indicating a potential role of SoS as a biomarker in detecting immobilization-induced fatty muscular degeneration not visible on B-mode ultrasound.


Assuntos
Traumatismos da Perna/diagnóstico por imagem , Músculo Esquelético/diagnóstico por imagem , Atrofia Muscular/diagnóstico por imagem , Restrição Física/efeitos adversos , Ultrassonografia/métodos , Adulto , Idoso , Moldes Cirúrgicos/efeitos adversos , Feminino , Humanos , Perna (Membro)/diagnóstico por imagem , Perna (Membro)/fisiopatologia , Traumatismos da Perna/fisiopatologia , Traumatismos da Perna/terapia , Masculino , Pessoa de Meia-Idade , Músculo Esquelético/fisiopatologia , Atrofia Muscular/etiologia , Projetos Piloto , Estudos Prospectivos , Reprodutibilidade dos Testes , Som , Adulto Jovem
3.
Undersea Hyperb Med ; 48(1): 59-72, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33648035

RESUMO

It is widely accepted that bubbles are a necessary but insufficient condition for the development of decompression sickness. However, open questions remain regarding the precise formation and behavior of these bubbles after an ambient pressure reduction (decompression), primarily due to the inherent difficulty of directly observing this phenomenon in vivo. In decompression research, information about these bubbles after a decompression is gathered via means of ultrasound acquisitions. The ability to draw conclusions regarding decompression research using ultrasound is highly influenced by the variability of the methodologies and equipment utilized by different research groups. These differences play a significant role in the quality of the data and thus the interpretation of the results. The purpose of this review is to provide a technical overview of the use of ultrasound in decompression research, particularly Doppler and brightness (B)-mode ultrasound. Further, we will discuss the strengths and limitations of these technologies and how new advancements are improving our ability to understand bubble behavior post-decompression.


Assuntos
Pesquisa Biomédica/métodos , Doença da Descompressão/diagnóstico por imagem , Ecocardiografia Doppler/métodos , Ultrassonografia Doppler/métodos , Descompressão , Doença da Descompressão/etiologia , Mergulho/fisiologia , Ecocardiografia Doppler/tendências , Embolia Aérea/diagnóstico por imagem , Embolia Aérea/etiologia , Humanos , Design de Software , Som , Transdutores , Ultrassonografia Doppler/instrumentação , Ultrassonografia Doppler/tendências
4.
Mar Pollut Bull ; 165: 112129, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33588103

RESUMO

Noise pollution is an anthropogenic stressor that is increasingly recognized for its negative impact on the physiology, behavior and fitness of marine organisms. Driven by the recent expansion of maritime shipping, artisanal fishing and tourism (e.g., motorboats used for recreational purpose), underwater noise increased greatly on coral reefs. In this review, we first provide an overview on how reef organisms sense and use sound. Thereafter we review the current knowledge on how underwater noise affects different reef organisms. Although the majority of available examples are limited to few fish species, we emphasize how the impact of noise differs based on an organisms' acoustic sensitivity, mobility and developmental stage, as well as between noise type, source and duration. Finally, we highlight measures available to governments, the shipping industry and individual users and provide directions for polices and research aimed to manage this global issue of noise emission on coral reefs.


Assuntos
Antozoários , Recifes de Corais , Animais , Ecossistema , Peixes , Ruído/efeitos adversos , Navios , Som
5.
Nat Commun ; 12(1): 1040, 2021 02 15.
Artigo em Inglês | MEDLINE | ID: mdl-33589613

RESUMO

Animals exhibit innate defense behaviors in response to approaching threats cued by the dynamics of sensory inputs of various modalities. The underlying neural circuits have been mostly studied in the visual system, but remain unclear for other modalities. Here, by utilizing sounds with increasing (vs. decreasing) loudness to mimic looming (vs. receding) objects, we find that looming sounds elicit stereotypical sequential defensive reactions: freezing followed by flight. Both behaviors require the activity of auditory cortex, in particular the sustained type of responses, but are differentially mediated by corticostriatal projections primarily innervating D2 neurons in the tail of the striatum and corticocollicular projections to the superior colliculus, respectively. The behavioral transition from freezing to flight can be attributed to the differential temporal dynamics of the striatal and collicular neurons in their responses to looming sound stimuli. Our results reveal an essential role of the striatum in the innate defense control.


Assuntos
Córtex Auditivo/fisiologia , Corpo Estriado/fisiologia , Reação de Fuga/fisiologia , Reação de Congelamento Cataléptica/fisiologia , Instinto , Estimulação Acústica , Animais , Córtex Auditivo/anatomia & histologia , Percepção Auditiva/fisiologia , Corpo Estriado/anatomia & histologia , Sinais (Psicologia) , Feminino , Masculino , Camundongos , Camundongos Endogâmicos C57BL , Camundongos Transgênicos , Neurônios/citologia , Neurônios/fisiologia , Som , Colículos Superiores/anatomia & histologia , Colículos Superiores/fisiologia
6.
PLoS One ; 16(2): e0246328, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33544744

RESUMO

To investigate if the anxiety associated with coronavirus disease 2019 (COVID-19) is a promoting factor to tinnitus. A retrospective research design collected from 188 tinnitus patients, was used to compare the clinical characteristics of tinnitus between the patients in 2020 under pandemic pressure and those from the matching period in 2019. While anxiety was quantified using the Zung's Self-rating Anxiety Scale (SAS), tinnitus severity was evaluated using the Tinnitus Handicap Inventory (THI) questionnaire and the test of tinnitus loudness (TL). The assessments were repeated after the sound therapy plus educational counselling (STEC) for 38 patients in 2020 and 58 patients in 2019 and compared with EC alone therapy for 42 patients in 2020 and 17 patients in 2019. A large increase in anxiety was evident in 2020 in both case rate and SAS. The treatment of both methods was less effective in 2020. SAS, THI and TL were all deteriorated after the EC alone treatment in 2020, while an improvement was seen in 2019. This suggests that EC alone could not counteract the stress by COVID-19 at all, and the stress, if not managed well, can significantly increase the severity of tinnitus and associated anxiety. By using the EC subgroup in virtual control, we conclude that anxiety can serve as a promoting factor to tinnitus. We believe that this is the first study report that confirm the causative/promotive role of anxiety on tinnitus during COVID-19 pandemic.


Assuntos
Ansiedade/complicações , Zumbido/complicações , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Índice de Gravidade de Doença , Som , Inquéritos e Questionários , Zumbido/diagnóstico , Zumbido/terapia
7.
Behav Processes ; 185: 104357, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33592283

RESUMO

Synchronous behaviours occur when two or more animals display the same behaviour at the same time. However, the mechanisms underlying this synchrony are not well understood. In this study, we carried out an experiment to determine whether or not Bottlenose dolphins use acoustic cues when performing a known synchronised exercise. For this, we recorded three dolphins while they performed requested aerial jumps both individually or synchronously in pairs, with a hydrophone array and a 360° underwater video camera allowing the identification of the subject emitting vocalisations. Results indicated that in pairs, dolphins synchronised their jumps 100% of the time. Whether they jumped alone or in pairs, they produced click trains before and after 92% of jumps. No whistles or burst-pulsed sounds were emitted by the animals during the exercise. The acoustic localisation process allowed the successful identification of the vocalising subject in 19.8% of all cases (N = 141). Our study showed that in all (n = 28) but one successful localisations, the click trains were produced by the same individual. It is worth noting that this individual was the oldest female of the group. This paper provides evidence suggesting that during synchronous behaviours, dolphins use acoustic cues, and more particularly click trains, to coordinate their movements; possibly by eavesdropping on the clicks or echoes produced by one individual leading the navigation.


Assuntos
Golfinho Nariz-de-Garrafa , Ecolocação , Acústica , Animais , Feminino , Humanos , Som , Espectrografia do Som , Vocalização Animal
8.
Nat Commun ; 12(1): 314, 2021 01 12.
Artigo em Inglês | MEDLINE | ID: mdl-33436635

RESUMO

Detecting the direction of frequency modulation (FM) is essential for vocal communication in both animals and humans. Direction-selective firing of neurons in the primary auditory cortex (A1) has been classically attributed to temporal offsets between feedforward excitatory and inhibitory inputs. However, it remains unclear how cortical recurrent circuitry contributes to this computation. Here, we used two-photon calcium imaging and whole-cell recordings in awake mice to demonstrate that direction selectivity is not caused by temporal offsets between synaptic currents, but by an asymmetry in total synaptic charge between preferred and non-preferred directions. Inactivation of cortical somatostatin-expressing interneurons (SOM cells) reduced direction selectivity, revealing its cortical contribution. Our theoretical models showed that charge asymmetry arises due to broad spatial topography of SOM cell-mediated inhibition which regulates signal amplification in strongly recurrent circuitry. Together, our findings reveal a major contribution of recurrent network dynamics in shaping cortical tuning to behaviorally relevant complex sounds.


Assuntos
Córtex Auditivo/fisiologia , Rede Nervosa/fisiologia , Animais , Potenciais Pós-Sinápticos Excitadores , Interneurônios/metabolismo , Camundongos Endogâmicos C57BL , Modelos Biológicos , Dinâmica não Linear , Somatostatina/metabolismo , Som , Sinapses/metabolismo
9.
Artigo em Inglês | MEDLINE | ID: mdl-33440710

RESUMO

In public, the role of a fire alarm is to induce a person to a certain recognition of potential danger, resulting in that person taking appropriate evacuation action. Unfortunately, the sound of the fire alarm is not internationally standardized yet, except for recommending the use of a signal with a regular temporal pattern (or T-3 pattern). To identify the effective alarm sound, the present study investigated a relationship between acoustic characteristics of the fire alarm and its subjective psychoacoustic recognition and objective electroencephalography (EEG) responses for 50 young and older listeners. As the stimuli, six different types of alarms were applied: bell, slow whoop, T-3 520 Hz, T-3 3100 Hz, and two simulated T-3 sounds (i.e., 520 and 3100 Hz) to which older adults with age-related hearing loss seemed to hear. While listening to the sounds, the EEG was recorded by each individual. The psychoacoustic recognition was also evaluated by using a questionnaire consisting of three subcategories, i.e., arousal, urgency, and immersion. The subjective responses resulted in a statistically significant difference between the types of sound. In particular, the fire alarms had acoustic features of high frequency or gradually increased frequencies such as T-3 3100 Hz, bell, and slow whoop, representing effective sounds to induce high arousal and urgency, although they also showed a limitation in being widely transmitted and vulnerable to background noise environment. Interestingly, there was a meaningful interaction effect between the sounds and age groups for the urgency and immersion, indicating that the bell was quite highly recognized in older adults. In general, EEG data showed that alpha power was decreased and gamma power was increased in all sounds, which means a relationship with negative emotions such as high arousal and urgency. Based on the current findings, we suggest using fire alarm sounds with acoustic features of high frequencies in indoor and/or public places.


Assuntos
Percepção Auditiva , Som , Estimulação Acústica , Idoso , Encéfalo , Humanos , Psicoacústica , Reconhecimento Psicológico
10.
Environ Pollut ; 270: 116184, 2021 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-33360067

RESUMO

Anthropogenic noise underwater is increasingly recognized as a pollutant for marine ecology, as marine life often relies on sound for orientation and communication. However, noise may not only interfere with processes mediated through sound, but also have effects across sensory modalities. To understand the mechanisms of the impact of anthropogenic sound to its full extent, we also need to study cross-sensory interference. To study this, we examined the effect of boat sound playbacks on olfactory-mediated food finding behaviour of shore crabs. We utilized opaque T-mazes with a consistent water flow from both ends towards the starting zone, while one end contained a dead food item. In this way, there were no visual or auditory cues and crabs could only find the food based on olfaction. We did not find an overall effect of boat sound on food finding success, foraging duration or walking distance. However, after excluding deviant data from one out of the six different boat stimuli, we found that crabs were faster to reach the food during boat sound playbacks. These results, with and without the deviant data, seem to contradict an earlier field study in which fewer crabs aggregated around a food source during elevated noise levels. We hypothesise that this difference could be explained by a difference in hunger level, with the current T-maze crabs being hungrier than the free-ranging crabs. Hunger level may affect the motivation to find food and the decision to avoid or take risks, but further research is needed to test this. In conclusion, we did not find unequivocal evidence for a negative impact of boat sound on the processing or use of olfactory cues. Nevertheless, the distinct pattern warrants follow up and calls for even larger replicate samples of acoustic stimuli for noise exposure experiments.


Assuntos
Braquiúros , Animais , Ruído , Navios , Olfato , Som
11.
Methods Mol Biol ; 2202: 189-197, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-32857356

RESUMO

The most common way to demonstrate the reactive oxygen species (ROS)-mediated pathways in photodynamic therapy (PDT) and in sonodynamic therapy (SDT) is the use of specific ROS inhibitors. We present a general method to establish the relative efficiency of different sonosensitizers which produce the same ROS. To demonstrate it, we use peroxides as sonosensitizers which produce singlet molecular oxygen. The method is easily generalized by all types of ROS.


Assuntos
Estimulação Acústica/métodos , Fotoquimioterapia/métodos , Espécies Reativas de Oxigênio/análise , Apoptose , Humanos , Oxigênio Singlete/análise , Oxigênio Singlete/metabolismo , Som
12.
Acta Psychol (Amst) ; 213: 103236, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33360343

RESUMO

Sketching while narrating is effective for eliciting information and veracity cues in single interviews. In the current research, we tested this technique in multiple interviews. Participants were interviewed three times over three weeks about a genuine (truth tellers) or a fabricated (lie tellers) memorable event. They sketched while narrating in Week 1, Week 2, Weeks 1 and 2, or not at all (verbal statement only). Statements were coded for total, core, peripheral, and common knowledge details, self-handicapping strategies, complications, plausibility, and proportions of complications and core details. In the third interview and across interviews, the Sketch instruction resulted in a higher proportion of core details. Truth tellers reported more total and core details and complications and fewer common knowledge details and exhibited a higher proportion of complications than lie tellers. Truth tellers' stories also sounded more plausible than lie tellers' stories. The interaction effects were not significant. Thus, sketching while narrating seemed to have a similar effect on truth tellers and lie tellers in the current study.


Assuntos
Decepção , Detecção de Mentiras , Sinais (Psicologia) , Humanos , Som
13.
Proc Biol Sci ; 287(1941): 20202337, 2020 12 23.
Artigo em Inglês | MEDLINE | ID: mdl-33323086

RESUMO

Music plays a more important role in our life than just being an entertainment. For example, it can be used as an anti-anxiety therapy of human and animals. However, the unsafe listening of loud music triggers hearing loss in millions of young people and professional musicians (rock, jazz and symphony orchestra) owing to exposure to damaging sound levels using personal audio devices or at noisy entertainment venues including nightclubs, discotheques, bars and concerts. Therefore, it is important to understand how loud music affects us. In this pioneering study on healthy mice, we discover that loud rock music below the safety threshold causes opening of the blood-brain barrier (OBBB), which plays a vital role in protecting the brain from viruses, bacteria and toxins. We clearly demonstrate that listening to loud music during 2 h in an intermittent adaptive regime is accompanied by delayed (1 h after music exposure) and short-lasting to (during 1-4 h) OBBB to low and high molecular weight compounds without cochlear and brain impairments. We present the systemic and molecular mechanisms responsible for music-induced OBBB. Finally, a revision of our traditional knowledge about the BBB nature and the novel strategies in optimizing of sound-mediated methods for brain drug delivery are discussed.


Assuntos
Barreira Hematoencefálica/fisiologia , Música , Adolescente , Animais , Feminino , Nível de Saúde , Humanos , Masculino , Camundongos , Ruído , Som
14.
Int J Mol Sci ; 22(1)2020 Dec 25.
Artigo em Inglês | MEDLINE | ID: mdl-33375749

RESUMO

Mechanical vibrations seem to affect the behaviour of different cell types and the functions of different organs. Pressure waves, including acoustic waves (sounds), could affect cytoskeletal molecules via coherent changes in their spatial organization and mechano-transduction signalling. We analyzed the sounds spectra and their fractal features. Cardiac muscle HL1 cells were exposed to different sounds, were stained for cytoskeletal markers (phalloidin, beta-actin, alpha-tubulin, alpha-actinin-1), and studied with multifractal analysis (using FracLac for ImageJ). A single cell was live-imaged and its dynamic contractility changes in response to each different sound were analysed (using Musclemotion for ImageJ). Different sound stimuli seem to influence the contractility and the spatial organization of HL1 cells, resulting in a different localization and fluorescence emission of cytoskeletal proteins. Since the cellular behaviour seems to correlate with the fractal structure of the sound used, we speculate that it can influence the cells by virtue of the different sound waves' geometric properties that we have photographed and filmed. A theoretical physical model is proposed to explain our results, based on the coherent molecular dynamics. We stress the role of the systemic view in the understanding of the biological activity.


Assuntos
Estimulação Acústica , Modelos Teóricos , Som , Biomarcadores , Células Cultivadas , Imunofluorescência , Mecanotransdução Celular , Microscopia Confocal , Projetos Piloto , Tubulina (Proteína)/metabolismo
15.
Mar Pollut Bull ; 160: 111646, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-33181928

RESUMO

The seabed off North West Europe contains much unexploded ordnance (UXO), posing a hazard to offshore developments such as windfarms. The typical removal method is through high-order detonation of a donor charge placed adjacent to the UXO. This method poses a risk of injury or death to marine mammals and other fauna from the high sound levels produced. This paper describes a controlled field experiment to compare the sound produced by high-order detonations with a low-order disposal method called deflagration, which uses a shaped charge of modest size, is less energetic, and offers reduced environmental impact from lower acoustic output. The results demonstrate a substantial reduction over high order detonation, with the peak sound pressure level and sound exposure level being more than 20 dB lower for the deflagration, and with the acoustic output depending only on the size of the shaped charge (rather than the size of the UXO).


Assuntos
Acústica , Som , Europa (Continente)
16.
Mar Pollut Bull ; 160: 111660, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-33181937

RESUMO

The article presents the results from a research project investigating acoustic climate changes in the Gdansk Deep based on data extending from 1902 to 2019. This part of the southern Gotland Basin, is rarely discussed in the scientific literature. The speed of sound in the seawater is a function of temperature, salinity, and depth. In such shallow sea as Baltic Sea, the impact of depth is not substantial. The other two factors shape the hydroacoustic conditions. In the upper layer of seawater, the dominating factor is heat exchange at the water-atmosphere interface. The observed climate warming is reflected in the water temperature rise, which results in an increased speed of sound in the upper water layer. After years of sporadic salty inflows from the North Sea, the frequency of the phenomenon has increased since 2014. As a result, the salinity at the bottom exceeds values typical for that area.


Assuntos
Mudança Climática , Água do Mar , Países Bálticos , Mar do Norte , Oceanos e Mares , Som
17.
Mar Pollut Bull ; 160: 111664, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-33181939

RESUMO

Although down-the-hole (DTH) pile driving is increasingly used for in-water pile installation, the characteristics of underwater noise from DTH pile driving is largely undocumented and unstudied. This study presents a comprehensive analysis of the noise characteristics during DTH pile driving of two steel pipe piles in shallow waters off southeast Alaska. The results showed that single-strike sound exposure levels measured at 10 m were 147 and 145 dB re 1 µPa2s with a total of 21,742 and 38,631 hammer strikes, with cumulative sound exposure levels to install each pile at 192 and 191 dB re 1 µPa2s, respectively. Though noise levels from a single strike was lower than impact pile driving of a similar pile, the cumulative sound exposure levels are likely comparable due to the much higher striking rate.


Assuntos
Ruído , Som , Alaska , Ilhas , Espectrografia do Som
18.
Mar Pollut Bull ; 160: 111680, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-33181953

RESUMO

Anthropogenic sound can affect fish behaviour and physiology which may affect their well-being. However, it remains a major challenge to translate such effects to consequences for fitness at an individual and population level. For this, energy budget models have been developed, but suitable data to parametrize these models are lacking. A first step towards such parametrization concerns the objective quantification of behavioural states at high resolution. We experimentally exposed individual Atlantic cod (Gadus morhua) in a net pen to the playback of seismic airgun sounds. We demonstrated that individual cod in the net pen did not change their swimming patterns immediately at the onset of the sound exposure. However, several individuals changed their time spent in three different behavioural states during the 1 h exposure. This may be translated to changes in energy expenditure and provide suitable input for energy budget models that allow predictions about fitness and population consequences.


Assuntos
Gadus morhua , Animais , Comportamento Animal , Metabolismo Energético , Humanos , Som , Natação
19.
Nat Commun ; 11(1): 4939, 2020 10 02.
Artigo em Inglês | MEDLINE | ID: mdl-33009390

RESUMO

Acoustic communication is enabled by the evolution of specialised hearing and sound producing organs. In this study, we performed a large-scale macroevolutionary study to understand how both hearing and sound production evolved and affected diversification in the insect order Orthoptera, which includes many familiar singing insects, such as crickets, katydids, and grasshoppers. Using phylogenomic data, we firmly establish phylogenetic relationships among the major lineages and divergence time estimates within Orthoptera, as well as the lineage-specific and dynamic patterns of evolution for hearing and sound producing organs. In the suborder Ensifera, we infer that forewing-based stridulation and tibial tympanal ears co-evolved, but in the suborder Caelifera, abdominal tympanal ears first evolved in a non-sexual context, and later co-opted for sexual signalling when sound producing organs evolved. However, we find little evidence that the evolution of hearing and sound producing organs increased diversification rates in those lineages with known acoustic communication.


Assuntos
Acústica , Evolução Biológica , Gafanhotos/classificação , Gafanhotos/genética , Filogenia , Vocalização Animal , Animais , Teorema de Bayes , Genoma Mitocondrial , Gafanhotos/anatomia & histologia , Audição/fisiologia , Modelos Biológicos , Som , Fatores de Tempo , Transcriptoma/genética
20.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 208-212, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33017966

RESUMO

Identifying the presence of sputum in the lung is essential in detection of diseases such as lung infection, pneumonia and cancer. Cough type classification (dry/wet) is an effective way of examining presence of lung sputum. This is traditionally done through physical exam in a clinical visit which is subjective and inaccurate. This work proposes an objective approach relying on the acoustic features of the cough sound. A total number of 5971 coughs (5242 dry and 729 wet) were collected from 131 subjects using Smartphone. The data was reviewed and annotated by a novel multi-layer labeling platform. The annotation kappa inter-rater agreement score is measured to be 0.81 and 0.37 for 1st and 2nd layer respectively. Sensitivity and specificity values of 88% and 86% are measured for classification between wet and dry coughs (highest across the literature).


Assuntos
Tosse , Pneumonia , Tosse/diagnóstico , Humanos , Sensibilidade e Especificidade , Som , Escarro
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