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1.
Mar Pollut Bull ; 150: 110792, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31910530

RESUMO

Pile driving occurs during construction of marine platforms, including offshore windfarms, producing intense sounds that can adversely affect marine animals. We quantified how a commercially and economically important squid (Doryteuthis pealeii: Lesueur 1821) responded to pile driving sounds recorded from a windfarm installation within this species' habitat. Fifteen-minute portions of these sounds were played to 16 individual squid. A subset of animals (n = 11) received a second exposure after a 24-h rest period. Body pattern changes, inking, jetting, and startle responses were observed and nearly all squid exhibited at least one response. These responses occurred primarily during the first 8 impulses and diminished quickly, indicating potential rapid, short-term habituation. Similar response rates were seen 24-h later, suggesting squid re-sensitized to the noise. Increased tolerance of anti-predatory alarm responses may alter squids' ability to deter and evade predators. Noise exposure may also disrupt normal intraspecific communication and ecologically relevant responses to sound.


Assuntos
Decapodiformes , Ruído , Estimulação Acústica , Animais , Ecossistema , Som
2.
Adv Exp Med Biol ; 1232: 113-119, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31893402

RESUMO

The prefrontal cortex (PFC) is sensitive to the stress exposure and involved in stress coping. And the effects of gum chewing on the stress have been studied using NIRS. However, when measuring NIRS on PFC during gum chewing, blood flows in shallow tissues (scalp, skin, muscle) might be affected. A NIRS used in the present study first, which has a short distance (1 cm) and the usual (3 cm) source-detector (S-D) regression, can allow eliminating shallow tissues effect of gum chewing. The aim of this study was to investigate the hypothesis that gum chewing activates the right prefrontal cortex (PFC) in stress coping against negative sounds (NS) from the International Affective Digitized Sounds-2 (IADS) as a mental stress task. NS showed activation in the right PFC. There was a significant difference between NS, and NS with Gum, where NS with Gum showed an increased PFC activity, increased alpha wave appearance rate, a higher value in heart rate level, and a higher VAS score indicating 'pleasant'. Gum chewing activated right PFC activity while exposed to negative sounds from IADS as a mental stress task.


Assuntos
Goma de Mascar , Mastigação , Som , Estresse Psicológico , Adaptação Psicológica , Adulto , Feminino , Humanos , Masculino , Córtex Pré-Frontal/fisiologia , Córtex Pré-Frontal/efeitos da radiação , Som/efeitos adversos , Estresse Psicológico/terapia , Adulto Jovem
3.
Pharm Res ; 37(3): 38, 2020 Jan 21.
Artigo em Inglês | MEDLINE | ID: mdl-31965333

RESUMO

PURPOSE: Asthma is a prevalent lung disorder that cause heavy burdens globally. Inhalation medicaments can relieve symptoms, improve lung function and, thus, the quality of life. However, it is well-documented that patients often do not get the prescribed dose out of an inhaler and the deposition of drug is suboptimal, due to incorrect handling of the device and wrong inhalation technique. This study aims to design and fabricate an acoustic dry powder inhaler (ADPI) for monitoring inhalation flow and related drug administration in order to evaluate whether the patient receives the complete dose out of the inhaler. METHODS: The devices were fabricated using 3D printing and the impact of the acoustic element geometry and printing resolution on the acoustic signal was investigated. Commercial Foradil (formoterol fumarate) capsules were used to validate the availability of the ADPI for medication dose tracking. The acoustic signal was analysed with Partial-Least-Squares (PLS) regression. RESULTS: Indicate that specific acoustic signals could be generated at different air flow rates using a passive acoustic element with specific design features. This acoustic signal could be correlated with the PLS model to the air flow rate. A more distinct sound spectra could be acquired at higher printing resolution. The sound spectra from the ADPI with no capsule, a full capsule and an empty capsule are different which could be used for medication tracking. CONCLUSIONS: This study shows that it is possible to evaluate the medication quality of inhaled medicaments by monitoring the acoustic signal generated during the inhalation process.


Assuntos
Asma/tratamento farmacológico , Broncodilatadores/química , Inaladores de Pó Seco/instrumentação , Fumarato de Formoterol/química , Impressão Tridimensional , Acústica , Administração por Inalação , Asma/fisiopatologia , Broncodilatadores/administração & dosagem , Sistemas de Liberação de Medicamentos/instrumentação , Desenho de Equipamento/instrumentação , Fumarato de Formoterol/administração & dosagem , Humanos , Análise dos Mínimos Quadrados , Pulmão/metabolismo , Monitorização Fisiológica/instrumentação , Pós/química , Pós/farmacologia , Análise de Regressão , Som
5.
Water Res ; 169: 115187, 2020 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-31671294

RESUMO

There is a pressing need for efficient biological treatment systems for the removal of organic compounds in greywater given the rapid increase in household wastewater produced as a consequence of rapid urbanisation. Moreover, proper treatment of greywater allows its reuse that can significantly reduce the demand for freshwater supplies. Herein, we demonstrate the possibility of enhancing the removal efficiency of solid contaminants from greywater using MHz-order surface acoustic waves (SAWs). A key distinction of the use of these high frequency surface acoustic waves, compared to previous work on its lower frequency (kHz order) bulk ultrasound counterpart for wastewater treatment, is the absence of cavitation, which can inflict considerable damage on bacteria, thus limiting the intensity and duration, and hence the efficiency enhancement, associated with the acoustic exposure. In particular, we show that up to fivefold improvement in the removal efficiency can be obtained, primarily due to the ability of the acoustic pressure field in homogenizing and reducing the size of bacterial clusters in the sample, therefore providing a larger surface area that promotes greater bacteria digestion. Alternatively, the SAW exposure allows the reduction in the treatment duration to achieve a given level of removal efficiency, thus facilitating higher treatment rates and hence processing throughput. Given the low-cost of the miniature chipscale platform, these promising results highlight its possibility for portable greywater treatment for domestic use or for large-scale industrial wastewater processing through massive parallelization.


Assuntos
Eliminação de Resíduos Líquidos , Águas Residuárias , Bactérias , Som
7.
J Environ Manage ; 253: 109722, 2020 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-31666215

RESUMO

Improvement of the sound environment is essential for improving the overall quality of the urban environment and for reflecting the characteristics of a city. Unfortunately, some soundscapes in cities are gradually being destroyed by the rapid development. Therefore, it would appear that the preservation of soundscapes is as necessary and crucial as noise control in cities. In this paper two field studies were carried out at two stages to explore the types and characteristics of urban soundscapes that should be preserved, based on the example of Tianjin, China. At stage one, 2504 respondents participated in social surveys to recommend the soundscapes worthy of preservation in the city. At stage two, a group soundscape walk with twenty-three participants was carried out to explore the characteristics of soundscapes worthy of preservation suggested by the respondents at the first stage. The following results were obtained: (1) regarding the attitude towards the urgency of soundscape preservation, 79% of the respondents thought it was urgent or very urgent, with an average score of 4.04 (five-point numeric scale was used and five meant very urgent). (2) The majority of soundscapes worthy of preservation were located in urban parks and historic districts with respective proportions of 66% and 20%. The top three sound source categories of these soundscapes were social/communal sounds (talking, bells, laughter, and sounds from human activities), animal sounds (birdsong and sounds from non-domesticated animals) and water sounds. (3) Relaxation, vibrancy, representativeness, strength, and richness were principal characteristics of the soundscapes worthy of preservation. (4) Based on their characteristics, these soundscapes were classified into five clusters using hierarchical cluster analysis (HCA). They were clusters of relaxing nature soundscape, vibrant nature soundscape, vibrant human activity soundscape, culture-related soundscape and traditional soundscape. The dominant characteristic of each cluster was driven by its sound mark rather than the dominant sound.


Assuntos
Parques Recreativos , Som , Animais , Atitude , China , Cidades , Humanos
8.
J Sci Food Agric ; 100(1): 431-440, 2020 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-31598969

RESUMO

BACKGROUND: Sound waves are emerging as a potential biophysical alternative to traditional methods for enhancing plant growth and phytochemical contents. However, little information is available on the improvement of the concentration of functional metabolites like flavonoids in sprouts using sound waves. In this study, different frequencies of sound waves with short and long exposure times were applied to three important varieties to improve flavonoid content. The aim of this study was to investigate the effect of sound waves on flavonoid content on the basis of biochemical and molecular characteristics. RESULTS: We examined the effects of various sound wave treatments (250 Hz to 1.5 kHz) on flavonoid production in alfalfa (Medicago sativa), broccoli (Brassica oleracea) and red young radish (Raphanus sativus). The results showed that sound wave treatments differentially altered the total flavonoid contents depending upon the growth stages, species and frequency of and exposure time to sound waves. Sound wave treatments of alfalfa (250 Hz), broccoli sprouts (800 Hz) and red young radish sprouts (1 kHz) increased the total flavonoid content by 200%, 35% and 85%, respectively, in comparison with untreated control. Molecular analysis showed that sound waves induce the expression of genes of the flavonoid biosynthesis pathway, which positively corresponds to the flavonoid content. Moreover, the sound wave treatment significantly improves the antioxidant efficiency of sprouts. CONCLUSIONS: The significant improvement of flavonoid content in sprouts with sound waves makes their use a potential and promising technology for the production of agriculture-based functional foods. © 2019 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.


Assuntos
Brassica/efeitos da radiação , Flavonoides/química , Medicago sativa/efeitos da radiação , Raphanus/efeitos da radiação , Brassica/química , Brassica/crescimento & desenvolvimento , Medicago sativa/química , Medicago sativa/crescimento & desenvolvimento , Raphanus/química , Raphanus/crescimento & desenvolvimento , Som
9.
Sci Total Environ ; 707: 135403, 2020 Mar 10.
Artigo em Inglês | MEDLINE | ID: mdl-31864000

RESUMO

There has been a body of research examining the sounds produced in landscapes. These sounds are commonly defined as soundscapes, however, the term is often used in different contexts. To understand the various meanings attributed to soundscapes, we identified how soundscapes are represented in the scientific literature and identified current knowledge gaps in soundscape research focusing on terrestrial environments. We conducted a quantitative review of published papers with the keyword soundscape available at Web of Science and Scopus databases. A total of 1309 abstracts and a subset of about 5% (N = 68) complete papers and reviews published from 1985 to 2017 were read and analysed, identifying types of sound, types of environment and focal species studied, as well as study regions and climates. By identifying the current focus of research, we also identified gaps and research opportunities. Research was biased towards temperate regions, terrestrial environments, and the impacts on humans in urban areas. Although most of the world's biodiversity is concentrated in tropical wilderness areas, these regions had fewer studies attributed to them. Given the importance of tropical landscapes for biodiversity conservation, we strongly suggest that more research should be undertaken in the tropics, with a particular focus on wildlife in these regions. Furthermore, soundscape research (methods and tools) should increasingly target the anthropogenic impacts on wildlife, including behavioural and physiological changes, alongside the current focus on human-sound interactions and the approach used by bioacoustics methods.


Assuntos
Animais Selvagens , Animais , Biodiversidade , Aves , Clima , Humanos , Som
10.
Vet J ; 253: 105380, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31685138

RESUMO

Cough is an important respiratory protective mechanism, which when persistent also contributes to disease pathology. It is therefore both a marker for and a target of therapeutic intervention. In dogs, assessment of cough is subjective, generally based on owner's perceptions of clinical signs. In humans, acoustic cough monitoring provides objective data on cough frequency by examining acoustic waveforms. We hypothesized that healthy mesocephalic dogs would demonstrate characteristic cough waveforms which could be distinguished from other acoustic behaviors (AB); whine, bark, growl, lick, drink, chew and throat-clear. Data were obtained from 10 healthy employee-owned dogs. Acoustic behaviors were recorded using a CTA-laryngeal-microphone and analyzed using RavenPro bioacoustics software for nine objective acoustic parameters (AP). Similarity between AB were assessed using a one-way analysis of similarity (ANOSIM) with a P<0.001 significance level. Inter- and intra-group statistical analysis was performed using a one-way ANOVA on ranks with P<0.05 significance level. With the exception of throat-clear, cough was dissimilar to every other evaluated AB (P<0.0001), with significant differences in one or more of the analyzed waveform parameters (P<0.001 for each). No between-subject differences were identified between cough and throat-clear groups for any parameter. All other behaviors showed statistically significant within-group variation (P<0.001). Cough and throat-clear (a clinically similar mechanism to protect the airways) have repeatable acoustic features that are distinguishable from other common AB and are consistent between dogs. Acoustic monitoring may provide an objective means for evaluating cough frequency and intensity in dogs with respiratory disease and assessing response to therapeutic intervention.


Assuntos
Tosse/veterinária , Doenças do Cão/diagnóstico , Cães/fisiologia , Animais , Tosse/diagnóstico , Feminino , Masculino , Reprodutibilidade dos Testes , Índice de Gravidade de Doença , Som
11.
Int J Prosthodont ; 32(6): 475-481, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31664263

RESUMO

PURPOSE: To determine the effectiveness of anterior repositioning splint (ARS) therapy on elimination of temporomandibular joint (TMJ) sounds in patients with internal derangement. MATERIALS AND METHODS: A total of 26 patients with 44 TMJs with internal derangement according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) were selected. These patients used an ARS for 6 weeks. The sounds of both the right and left TMJs were recorded with a specifically developed sound recording system before and after ARS therapy. The evaluation of sound was performed using evolutionary spectral analysis on the program MATLAB. Parameters such as sound type, amplitude, duration, and energy were evaluated in a time-frequency analysis. Changes in mean amplitude levels of opening/closing TMJ sounds before therapy and 6 weeks after insertion of splints were compared using paired-samples t test. The level of significance was set at 5%. RESULTS: The patients showed a decrease in the mean amplitude and energy values of opening/closing sounds after 6 weeks of ARS use (P < .05). According to evolutionary spectral analysis, the use of ARS was efficient for 7 of 19 right joints (37%) and 11 of 25 left joints (44%). CONCLUSION: The results suggest that the use of 6-week ARS reduced amplitude and energy parameters of TMJ sounds; however, it did not completely eliminate TMJ sounds.


Assuntos
Luxações Articulares , Transtornos da Articulação Temporomandibular , Humanos , Som , Contenções , Disco da Articulação Temporomandibular
12.
PLoS Biol ; 17(10): e3000449, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31574079

RESUMO

Humans and other animals effortlessly identify natural sounds and categorize them into behaviorally relevant categories. Yet, the acoustic features and neural transformations that enable sound recognition and the formation of perceptual categories are largely unknown. Here, using multichannel neural recordings in the auditory midbrain of unanesthetized female rabbits, we first demonstrate that neural ensemble activity in the auditory midbrain displays highly structured correlations that vary with distinct natural sound stimuli. These stimulus-driven correlations can be used to accurately identify individual sounds using single-response trials, even when the sounds do not differ in their spectral content. Combining neural recordings and an auditory model, we then show how correlations between frequency-organized auditory channels can contribute to discrimination of not just individual sounds but sound categories. For both the model and neural data, spectral and temporal correlations achieved similar categorization performance and appear to contribute equally. Moreover, both the neural and model classifiers achieve their best task performance when they accumulate evidence over a time frame of approximately 1-2 seconds, mirroring human perceptual trends. These results together suggest that time-frequency correlations in sounds may be reflected in the correlations between auditory midbrain ensembles and that these correlations may play an important role in the identification and categorization of natural sounds.


Assuntos
Potenciais de Ação/fisiologia , Mesencéfalo/fisiologia , Modelos Neurológicos , Rede Nervosa/fisiologia , Neurônios/fisiologia , Reconhecimento Fisiológico de Modelo/fisiologia , Estimulação Acústica/métodos , Animais , Eletrodos Implantados , Eletrofisiologia , Feminino , Mesencéfalo/anatomia & histologia , Rede Nervosa/anatomia & histologia , Neurônios/citologia , Coelhos , Som , Técnicas Estereotáxicas
13.
Nat Rev Genet ; 20(12): 703, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31578467
14.
Nat Commun ; 10(1): 4592, 2019 10 09.
Artigo em Inglês | MEDLINE | ID: mdl-31597928

RESUMO

Across vertebrates, progressive changes in vocal behavior during postnatal development are typically attributed solely to developing neural circuits. How the changing body influences vocal development remains unknown. Here we show that state changes in the contact vocalizations of infant marmoset monkeys, which transition from noisy, low frequency cries to tonal, higher pitched vocalizations in adults, are caused partially by laryngeal development. Combining analyses of natural vocalizations, motorized excised larynx experiments, tensile material tests and high-speed imaging, we show that vocal state transition occurs via a sound source switch from vocal folds to apical vocal membranes, producing louder vocalizations with higher efficiency. We show with an empirically based model of descending motor control how neural circuits could interact with changing laryngeal dynamics, leading to adaptive vocal development. Our results emphasize the importance of embodied approaches to vocal development, where exploiting biomechanical consequences of changing material properties can simplify motor control, reducing the computational load on the developing brain.


Assuntos
Callithrix/fisiologia , Laringe/fisiologia , Prega Vocal/fisiologia , Vocalização Animal/fisiologia , Algoritmos , Animais , Animais Recém-Nascidos , Callithrix/crescimento & desenvolvimento , Feminino , Laringe/crescimento & desenvolvimento , Masculino , Modelos Biológicos , Ruído , Som , Prega Vocal/crescimento & desenvolvimento
15.
Sensors (Basel) ; 19(20)2019 Oct 16.
Artigo em Inglês | MEDLINE | ID: mdl-31623215

RESUMO

Current cochlear implant (CI) systems provide substantial benefits for patients with severe hearing loss. However, they do not allow for 24/7 hearing, mainly due to the external parts that cannot be worn in all everyday situations. One of the key missing parts for a totally implantable CI (TICI) is the microphone, which thus far has not been implantable. The goal of the current project was to develop a concept for a packaging technology for state-of-the-art microelectromechanical systems (MEMS) microphones that record the liquid-borne sound inside the inner ear (cochlea) as a microphone signal input for a TICI. The packaging concept incorporates requirements, such as biocompatibility, long-term hermeticity, a high sensing performance and a form factor that allows sensing inside the human cochlea and full integration into the existing CI electrode array. The present paper (1) describes the sensor packaging concept and the corresponding numerical and experimental design verification process and (2) gives insight into new engineering solutions for sensor packaging. Overall, a packaging concept was developed that enables MEMS microphone technology to be used for a TICI system.


Assuntos
Implantes Cocleares , Orelha Interna/fisiopatologia , Auxiliares de Audição , Sistemas Microeletromecânicos , Humanos , Modelos Teóricos , Desenho de Prótese/métodos , Som , Transdutores
16.
PLoS Comput Biol ; 15(10): e1007430, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31626624

RESUMO

Perception of vocalizations and other behaviorally relevant sounds requires integrating acoustic information over hundreds of milliseconds. Sound-evoked activity in auditory cortex typically has much shorter latency, but the acoustic context, i.e., sound history, can modulate sound evoked activity over longer periods. Contextual effects are attributed to modulatory phenomena, such as stimulus-specific adaption and contrast gain control. However, an encoding model that links context to natural sound processing has yet to be established. We tested whether a model in which spectrally tuned inputs undergo adaptation mimicking short-term synaptic plasticity (STP) can account for contextual effects during natural sound processing. Single-unit activity was recorded from primary auditory cortex of awake ferrets during presentation of noise with natural temporal dynamics and fully natural sounds. Encoding properties were characterized by a standard linear-nonlinear spectro-temporal receptive field (LN) model and variants that incorporated STP-like adaptation. In the adapting models, STP was applied either globally across all input spectral channels or locally to subsets of channels. For most neurons, models incorporating local STP predicted neural activity as well or better than LN and global STP models. The strength of nonlinear adaptation varied across neurons. Within neurons, adaptation was generally stronger for spectral channels with excitatory than inhibitory gain. Neurons showing improved STP model performance also tended to undergo stimulus-specific adaptation, suggesting a common mechanism for these phenomena. When STP models were compared between passive and active behavior conditions, response gain often changed, but average STP parameters were stable. Thus, spectrally and temporally heterogeneous adaptation, subserved by a mechanism with STP-like dynamics, may support representation of the complex spectro-temporal patterns that comprise natural sounds across wide-ranging sensory contexts.


Assuntos
Córtex Auditivo/fisiologia , Percepção Auditiva/fisiologia , Estimulação Acústica , Potenciais de Ação/fisiologia , Adaptação Fisiológica/fisiologia , Animais , Feminino , Furões , Masculino , Modelos Neurológicos , Modelos de Interação Espacial , Plasticidade Neuronal , Neurônios/fisiologia , Ruído , Som
18.
Complement Ther Med ; 46: 62-68, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31519289

RESUMO

BACKGROUND: Tinnitus is the perception of sound when no external sound source is present. In some cases, this perception coincides with, or results in, stress. Tinnitus-related distress has been associated with increased levels of cortisol and elevated levels of sympathetic tone. Our primary hypothesis was that short-term sound exposure would reduce tinnitus perception and various physiological measures of stress. A secondary hypothesis was that a self-selected nature sound would reduce physiological markers of stress more than broadband noise. METHODS: Twenty-one participants with constant bothersome tinnitus underwent an audiological assessment. Measurements of blood pressure, heart rate, salivary cortisol and cortisone concentrations, and tinnitus ratings were carried out three times: prior to and, in a counterbalance order, after 30 min of broadband noise and after 30 min of a self-selected nature sound (from: ocean waves, stream, rain or shower sounds). RESULTS: Findings revealed significant reductions in blood pressure measurements following broadband noise. None of the other stress measures demonstrated a statistically significant change. Both broadband noise and nature sounds elicited significant improvements in ratings of tinnitus. CONCLUSIONS: While both sound types had a positive impact on many dimensions of tinnitus, only the broadband noise was associated with a reduction in blood pressure. These results are consistent with a complex interaction between sound and tinnitus and suggest a multifactorial basis to sound therapy that includes a reduction in arousal.


Assuntos
Biomarcadores/metabolismo , Som/efeitos adversos , Zumbido/metabolismo , Zumbido/fisiopatologia , Adulto , Idoso , Pressão Sanguínea/fisiologia , Feminino , Humanos , Hidrocortisona/metabolismo , Masculino , Pessoa de Meia-Idade , Adulto Jovem
19.
Artigo em Chinês | MEDLINE | ID: mdl-31550758

RESUMO

Objective: To study the response characteristics of the posterior intralaminar nucleus (PIN) of auditory thalamus in VGluT2-Cre transgenic adult mice when exposed to white noise and 10K pure tone stimulation. Methods: All adult male Vglut2-Cre mice (8-12 weeks) were used in this study between Oct, 2017 and Oct, 2018. Using the calcium signal fiber photometry method, optic fiber was employed to locate on PIN by injecting AAV-hSyn-DIO-GCaMP6m virus, and thereafter, the activity of the target cluster neurons during different acoustic stimuli was recorded. Matlab was used for data processing and statistical analysis. Results: (1)In both white noise and 10 kHz pure tone as a continuous three-second stimulation, the peak amplitude of calcium signal activity generated in PIN by white noise was superior to that of pure tone, the statistic result showed significantly difference (n=6, t=2.404, P=0.037 1) . (2)In addition, when white noise and 10K pure tone played as consecutive 3 or 5 pips within three-second stimulation, the stimulus-following ability in a consecutive 3 pulses play within 3 seconds was far better than a consecutive 5 pips play within 3 seconds (in both white noise and 10 kHz pure tone), yet consecutive 3 pips play showed greater signal attenuation speed than that in consecutive 5 pips play, the statistic result showed significantly difference (n=6, t=2.748 P=0.033 4) .(3)Regardless of the intra-group comparisons between white noise and 10 kHz pure tone stimulation, PIN showed better signal response in a consecutive 3 pips play than consecutive 5 pips play or a continuous three-second stimulation. When came to the statistical analysis, the acoustic response degree of a continuous three-second stimulation was an intermediate between two others, both consecutive 3 or 5 pips play showed significantly difference. Conclusions: The results suggest that under the same acoustic intensity, VGluT2-Cre transgenic adult mice's PIN shows greater signal response in white noise than pure tone. PIN shows greater signal attenuation to repetition play of 10 kHz pure tone, which implies PIN shows stronger adaptation to 10 kHz pure tone than to white noise. Lastly, PIN is more responsive to a complex sound information (white noise) than to simple sound information (pure tone).


Assuntos
Acústica , Neurônios , Tálamo , Estimulação Acústica , Animais , Limiar Auditivo , Masculino , Camundongos , Camundongos Transgênicos , Neurônios/fisiologia , Som , Tálamo/fisiologia
20.
Dokl Biochem Biophys ; 487(1): 247-250, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31559590

RESUMO

According to the results of theoretical and experimental analysis of the characteristics of the propagation of acoustic vibrations in the respiratory system, it is necessary to determine the resonant frequency of the respiratory tract to increase the vital capacity of the lungs by opening reserve alveoli by acoustic stimulation of the respiratory system and then to affect the respiratory system with scanning tonal sounds in the maximum sound absorption range (at a level of ±3 dB of the maximum absorption coefficient value).


Assuntos
Absorção Fisico-Química , Estimulação Acústica , Pulmão/fisiologia , Modelos Biológicos , Som , Pulmão/efeitos da radiação
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